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Holger Kirchner

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D Juhl; C Mosel; F Nawroth; A-M Funke; S M Dadgar; H Hagenström; Holger Kirchner; H Hennig
Detection of herpes simplex virus DNA in plasma of patients with primary but not with recurrent infection: implications for transfusion medicine?
Isabel Dorn; Pamela Lazar-Karsten; Stefanie Boie; Julika Ribbat; Dirk Hartwig; Birgit Driller; Holger Kirchner; Peter Schlenke
In vitro proliferation and differentiation of human CD34+ cells from peripheral blood into mature red blood cells with two different cell culture systems.
K B Faust; Doreen Finke; K Klempt-Giessing; K Randers; B Zachrau; Peter Schlenke; Holger Kirchner; Siegfried Goerg
Antigen-induced B cell apoptosis is independent of complement C4.

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2010: D Juhl; C Mosel; F Nawroth; A-M Funke; S M Dadgar; H Hagenström; Holger Kirchner; H Hennig
Detection of herpes simplex virus DNA in plasma of patients with primary but not with recurrent infection: implications for transfusion medicine?
Transfusion medicine (Oxford, England) 2010;20(1):38-47.
2008: Isabel Dorn; Pamela Lazar-Karsten; Stefanie Boie; Julika Ribbat; Dirk Hartwig; Birgit Driller; Holger Kirchner; Peter Schlenke
In vitro proliferation and differentiation of human CD34+ cells from peripheral blood into mature red blood cells with two different cell culture systems.
Transfusion 2008;48(6):1122-32.
2007: K B Faust; Doreen Finke; K Klempt-Giessing; K Randers; B Zachrau; Peter Schlenke; Holger Kirchner; Siegfried Goerg
Antigen-induced B cell apoptosis is independent of complement C4.
Clinical and experimental immunology 2007;150(1):132-9.
2007: Doreen Finke; Katharina Randers; Robert Hoerster; Holger Hennig; Rainer Zawatzky; Tony Marion; Christian Brockmann; Katja Klempt-Giessing; Kirsten Jacobsen; Holger Kirchner; Siegfried Goerg
Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.
European journal of immunology 2007;37(6):1702-9.
2007: Uta Fernekorn; Eugene C Butcher; Jochen Behrends; Christian M Karsten; Astrid Röbke; Torsten J Schulze; Holger Kirchner; Andrea Kruse
Selectin, platelet plays a critical role in granulocyte access to the pregnant mouse uterus under physiological and pathological conditions.
Biology of reproduction 2007;76(4):645-53.
2006: Malte Ziemann; Dagmar Steppat; Christian Brockmann; Gesa Washington; Holger Kirchner; Peter Schlenke
Selection of whole-blood donors for hemoglobin testing by use of historical hemoglobin values.
Transfusion 2006;46(12):2176-83.
2006: Jens Atzpodien; Holger Kirchner; U Rebmann; M Soder; U Gertenbach; Michael Siebels; Jan Roigas; R Raschke; S Salm; B Schwindl; S C Müller; S Hauser; C Leiber; Edith Huland; Hans Heinzer; S Siemer; Bernd Metzner; Hans Heynemann; P Fornara; Martina Reitz
Interleukin-2/interferon-alpha2a/13-retinoic acid-based chemoimmunotherapy in advanced renal cell carcinoma: results of a prospectively randomised trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN).
British journal of cancer 2006;95(4):463-9.
2006: Dirk Hartwig; C Schütte; JM Warnecke; Isabel Dorn; Holger Hennig; Holger Kirchner; Peter Schlenke
The large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon-alpha-stimulated host cells.
Journal of viral hepatitis 2006;13(3):150-7.
2004: Berit Zachrau; Doreen Finke; Katja Kropf; Hans-Juergen Gosink; Holger Kirchner; Siegfried Goerg
Antigen localization within the splenic marginal zone restores humoral immune response and IgG class switch in complement C4-deficient mice.
International immunology 2004;16(12):1685-90.
2004: Dirk Hartwig; Lutz Schoeneich; Jobst Greeve; Claudia Schütte; Isabel Dorn; Holger Kirchner; Holger Hennig
Interferon-alpha stimulation of liver cells enhances hepatitis delta virus RNA editing in early infection.
Journal of hepatology 2004;41(4):667-72.
2004: Jörg-Matthias Brand; Birgit Meller; Katharina von Hof; Jürgen Luhm; M Bähre; Holger Kirchner; Christoph Frohn
Kinetics and organ distribution of allogeneic natural killer lymphocytes transfused into patients suffering from renal cell carcinoma.
Stem cells and development 2004;13(3):307-14.
2004: Gerhard Heil; Jürgen Krauter; A Raghavachar; Lothar Bergmann; Dieter Hoelzer; W Fiedler; M Lübbert; L Noens; G Schlimok; Renate Arnold; Holger Kirchner; Arnold Ganser
Risk-adapted induction and consolidation therapy in adults with de novo AML aged
Annals of hematology 2004;83(6):336-44.

2004: Dirk Hartwig; Isabel Dorn; Holger Kirchner; Peter Schlenke
Recommendations for optimized settings of the Amicus Crescendo cell separator for the collection of CD34+ progenitor cells.
Transfusion 2004;44(5):758-63.
2004: Jörg-Matthias Brand; Christoph Frohn; Katharina Cziupka; Christian Brockmann; Holger Kirchner; Jürgen Luhm
Prolactin triggers pro-inflammatory immune responses in peripheral immune cells.
European cytokine network 2004;15(2):99-104.
2004: Jens Atzpodien; Holger Kirchner; U Jonas; L Bergmann; H Schott; Hans Heynemann; P Fornara; S A Loening; Jan Roigas; S C Müller; Heinrich Bodenstein; S Pomer; Bernd Metzner; U Rebmann; Ralph Oberneder; Michael Siebels; Thomas Wandert; T Puchberger; Martina Reitz
Interleukin-2- and interferon alfa-2a-based immunochemotherapy in advanced renal cell carcinoma: a Prospectively Randomized Trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(7):1188-94.
2004: Michael Müller-Steinhardt; Lutz Fricke; Brigitte Müller; Brigitte Ebel; Holger Kirchner; Christoph Härtel
Cooperative influence of the interleukin-6 promoter polymorphisms -597, -572 and -174 on long-term kidney allograft survival.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(3):402-6.
2004: Birgit Meller; Christoph Frohn; Jörg-Matthias Brand; Isabel Lauer; Lutz F Schelper; Katharina von Hof; Holger Kirchner; Eckart Richter; Manfred Baehre
Monitoring of a new approach of immunotherapy with allogenic (111)In-labelled NK cells in patients with renal cell carcinoma.
European journal of nuclear medicine and molecular imaging 2004;31(3):403-7.
2004: Detlef E Dietrich; Ute Hauser; Marion Peters; Yuanyuan Zhang; Martin Wiesmann; Mark Hasselmann; Sebastian Rudolf; Oliver Jüngling; Holger Kirchner; Thomas F Münte; Volker Arolt; Hinderk M Emrich; Sönke Johannes; Matthias Rothermundt
Target evaluation processing and serum levels of nerve tissue protein S100B in patients with remitted major depression.
Neuroscience letters 2004;354(1):69-73.
2004: Sebastian Rudolf; Peter Schlenke; Andreas Broocks; Marion Peters; Matthias Rothermundt; Volker Arolt; Holger Kirchner
Search for atypical lymphocytes in schizophrenia.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2004;5(1):33-7.
2004: Christoph Härtel; Nina Schumacher; Lutz Fricke; Brigitte Ebel; Holger Kirchner; Michael Müller-Steinhardt
Sensitivity of whole-blood T lymphocytes in individual patients to tacrolimus (FK 506): impact of interleukin-2 mRNA expression as surrogate measure of immunosuppressive effect.
Clinical chemistry 2004;50(1):141-51.
2003: Jörg-Matthias Brand; Christoph Frohn; Jürgen Luhm; Holger Kirchner; Peter Schmucker
Early alterations in the number of circulating lymphocyte subpopulations and enhanced proinflammatory immune response during opioid-based general anesthesia.
Shock (Augusta, Ga.) 2003;20(3):213-7.
2003: Volker Arolt; Marion Peters; Andreas Erfurth; Martin Wiesmann; Ulrich Missler; Sebastian Rudolf; Holger Kirchner; Matthias Rothermundt
S100B and response to treatment in major depression: a pilot study.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(4):235-9.
2003: Christoph Frohn; Lutz Dümbgen; Jörg-Matthias Brand; Siegfried Görg; Jürgen Luhm; Holger Kirchner
Probability of anti-D development in D- patients receiving D+ RBCs.
Transfusion 2003;43(7):893-8.
2003: Holger Hennig; Nikolaus Osterrieder; Michael Müller-Steinhardt; Hanns-Martin Teichert; Holger Kirchner; Klaus-Peter Wandinger
Detection of Marek's disease virus DNA in chicken but not in human plasma.
Journal of clinical microbiology 2003;41(6):2428-32.
2003: Arne Aue; Holger Hennig; Sabine Krüger; Barbara Closius; Holger Kirchner; Michael Seyfarth
Immunity against diphtheria and tetanus in German blood donors.
Medical microbiology and immunology 2003;192(2):93-7.
2003: Christoph Härtel; Hans-Joerg Hammers; Peter Schlenke; Lutz Fricke; Nina Schumacher; Holger Kirchner; Michael Müller-Steinhardt
Individual variability in cyclosporin A sensitivity: the assessment of functional measures on CD28-mediated costimulation of human whole blood T lymphocytes.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2003;23(2):91-9.
2002: Christoph Härtel; Lutz Fricke; Nina Schumacher; Holger Kirchner; Michael Müller-Steinhardt
Delayed cytokine mRNA expression kinetics after T-lymphocyte costimulation: a quantitative measure of the efficacy of cyclosporin A-based immunosuppression.
Clinical chemistry 2002;48(12):2225-31.
2002: Christoph Frohn; Maike Höppner; Peter Schlenke; Holger Kirchner; Petra Koritke; Jürgen Luhm
Anti-myeloma activity of natural killer lymphocytes.
British journal of haematology 2002;119(3):660-4.
2002: Michael Müller-Steinhardt; Christoph Härtel; Brigitte Müller; Holger Kirchner; Lutz Fricke
The interleukin-6 -174promoter polymorphism is associated with long-term kidney allograft survival.
Kidney international 2002;62(5):1824-7.
2002: Tobias Breidthardt; Christoph Frohn; Jürgen Luhm; Holger Kirchner; Jörg-Matthias Brand
Prolactin induces enhanced interferon gamma release in peripheral whole blood after stimulation with either PHA or LPS.
Immunobiology 2002;206(4):424-31.
2002: Holger Hennig; Ines Puchta; Jürgen Luhm; Peter Schlenke; Siegfried Goerg; Holger Kirchner
Frequency and load of hepatitis B virus DNA in first-time blood donors with antibodies to hepatitis B core antigen.
Blood 2002;100(7):2637-41.
2002: Jürgen Luhm; Jörg-Matthias Brand; Petra Koritke; Maike Höppner; Holger Kirchner; Christoph Frohn
Large-scale generation of natural killer lymphocytes for clinical application.
Journal of hematotherapy & stem cell research 2002;11(4):651-7.
2002: Dirk Hartwig; F Schläger; Peter Bucsky; Holger Kirchner; Peter Schlenke
Successful long-term erythrocytapheresis therapy in a patient with symptomatic sickle-cell disease using an arterio-venous fistula.
Transfusion medicine (Oxford, England) 2002;12(1):75-7.
2002: Michael Müller-Steinhardt; Holger Hennig; Holger Kirchner; Peter Schlenke
Prestorage WBC filtration of RBC units with soft-shell filters: filtration performance and impact on RBCs during storage for 42 days.
Transfusion 2002;42(2):153-8.
2002: Sebastian Rudolf; Marion Peters; Matthias Rothermundt; Volker Arolt; Holger Kirchner
The influence of typical and atypical neuroleptic drugs in the production of interleukin-2 and interferon-gamma in vitro.
Neuropsychobiology 2002;46(4):180-5.
2001: S Sheikhzadeh; Hans-Joerg Hammers; Dirk Hartwig; Holger Kirchner; Peter Schlenke
Improvement of the precision in CFU-GM and BFU-E counting by flow cytometry-based standardization of short-term culture assays.
Journal of hematotherapy & stem cell research 2001;10(6):881-5.
2001: Sabine Krüger; Michael Müller-Steinhardt; Holger Kirchner; Burkhard Kreft
A 5-year follow-up on antibody response after diphtheria and tetanus vaccination in hemodialysis patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2001;38(6):1264-70.
2001: Jens Atzpodien; Holger Kirchner; Hans-Jochen Illiger; Bernd Metzner; D Ukena; H Schott; P J Funke; Martin Gramatzki; S Jürgenson; Thomas Wandert; T Patzelt; Martina Reitz
IL-2 in combination with IFN- alpha and 5-FU versus tamoxifen in metastatic renal cell carcinoma: long-term results of a controlled randomized clinical trial.
British journal of cancer 2001;85(8):1130-6.
2001: Jörg-Matthias Brand; Peter Schmucker; Tobias Breidthardt; Holger Kirchner
Upregulation of IFN-gamma and soluble interleukin-2 receptor release and altered serum cortisol and prolactin concentration during general anesthesia.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2001;21(10):793-6.
2001: Holger Hennig; Jürgen Luhm; Dirk Hartwig; Harald Klüter; Holger Kirchner
A novel RT-PCR for reliable and rapid HCV RNA screening of blood donations.
Transfusion 2001;41(9):1100-6.
2001: Matthias Rothermundt; Volker Arolt; Martin Wiesmann; Ulrich Missler; Marion Peters; Sebastian Rudolf; Holger Kirchner
S-100B is increased in melancholic but not in non-melancholic major depression.
Journal of affective disorders 2001;66(1):89-93.
2001: Michael Müller-Steinhardt; N Kock; Christoph Härtel; Holger Kirchner; Jürgen Steinhoff
Production of monokines in patients under polysulphone haemodiafiltration is influenced by the ultrafiltration flow rate.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2001;16(9):1830-7.
2001: Matthias Rothermundt; Ulrich Missler; Volker Arolt; M Peters; J Leadbeater; Martin Wiesmann; Sebastian Rudolf; Klaus-Peter Wandinger; Holger Kirchner
Increased S100B blood levels in unmedicated and treated schizophrenic patients are correlated with negative symptomatology.
Molecular psychiatry 2001;6(4):445-9.
2001: Christoph Frohn; Lutz Fricke; J C Puchta; Holger Kirchner
The effect of HLA-C matching on acute renal transplant rejection.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2001;16(2):355-60.
2001: Wolfram J Jabs; Holger Hennig; M Kittel; Klaus Pethig; F Smets; Peter Bucsky; Holger Kirchner; Hans-Joachim Wagner
Normalized quantification by real-time PCR of Epstein-Barr virus load in patients at risk for posttransplant lymphoproliferative disorders.
Journal of clinical microbiology 2001;39(2):564-9.
2001: Hans Hoerauf; Harald Klüter; E Joachimmeyer; Johann Roider; Carsten Framme; P Schlenke; Holger Kirchner; H Lagua
Results of vitrectomy and the no-touch-technique using autologous adjuvants in macular hole treatment.
International ophthalmology 2001;24(3):151-9.
2001: Matthias Rothermundt; Volker Arolt; J Fenker; H Gutbrodt; M Peters; Holger Kirchner
Different immune patterns in melancholic and non-melancholic major depression.
European archives of psychiatry and clinical neuroscience 2001;251(2):90-7.
2000: H Hagenström; Peter Schlenke; Holger Hennig; Holger Kirchner; Harald Klüter
Quantification of platelet-associated IgG for differential diagnosis of patients with thrombocytopenia.
Thrombosis and haemostasis 2000;84(5):779-83.
2000: Matthias Rothermundt; Volker Arolt; J Leadbeater; M Peters; Sebastian Rudolf; Holger Kirchner
Cytokine production in unmedicated and treated schizophrenic patients.
Neuroreport 2000;11(15):3385-8.
2000: Wolfram J Jabs; Hans-Joachim Wagner; Peter Schlenke; Holger Kirchner
The primary and memory immune response to Epstein-Barr virus infection in vitro is characterized by a divergent production of IL-1beta/IL-6 and IL-10.
Scandinavian journal of immunology 2000;52(3):304-8.
2000: K Oevermann; Jan Buer; Reinhard Hoffmann; Anke Franzke; Andres J Schrader; T Patzelt; Holger Kirchner; Jens Atzpodien
Capecitabine in the treatment of metastatic renal cell carcinoma.
British journal of cancer 2000;83(5):583-7.
2000: Hans-Joerg Hammers; Holger Kirchner; Peter Schlenke
Ultraviolet-induced detection of halogenated pyrimidines: simultaneous analysis of DNA replication and cellular markers.
Cytometry 2000;40(4):327-35.
2000: Klaus-Peter Wandinger; Wolfram J Jabs; A Siekhaus; Stefanie Bubel; Peter Trillenberg; H Wagner; Karl Wessel; Holger Kirchner; Holger Hennig
Association between clinical disease activity and Epstein-Barr virus reactivation in MS.
Neurology 2000;55(2):178-84.
2000: Hans-Joachim Wagner; Wolfram J Jabs; F Smets; M Wessel; Lars Fischer; G Offner; Holger Kirchner; Peter Bucsky
Real-time polymerase chain reaction (RQ-PCR) for the monitoring of Epstein-Barr virus (EBV) load in peripheral blood mononuclear cells.
Klinische Pädiatrie 2000;212(4):206-10.
2000: Christoph Frohn; Christian Doehn; Christoph Durek; Andreas Böhle; Peter Schlenke; Dieter Jocham; Holger Kirchner
Feasibility of the adoptive transfusion of allogenic human leukocyte antigen-matched natural killer cells in patients with renal cell carcinoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(4):499-504.
2000: L Alvarez-Ossorio; Holger Kirchner; Harald Klüter; Peter Schlenke
Low ferritin levels indicate the need for iron supplementation: strategy to minimize iron-depletion in regular blood donors.
Transfusion medicine (Oxford, England) 2000;10(2):107-12.
2000: Volker Arolt; Matthias Rothermundt; Klaus-Peter Wandinger; Holger Kirchner
Decreased in vitro production of interferon-gamma and interleukin-2 in whole blood of patients with schizophrenia during treatment.
Molecular psychiatry 2000;5(2):150-8.
2000: C Hennig; Lothar Rink; U Fagin; Wolfram J Jabs; Holger Kirchner
The influence of naturally occurring heterophilic anti-immunoglobulin antibodies on direct measurement of serum proteins using sandwich ELISAs.
Journal of immunological methods 2000;235(1-2):71-80.
2000: Holger Hennig; Peter Schlenke; Holger Kirchner; I Bauer; B Schulte-Kellinghaus; H Bludau
Evaluation of newly developed microparticle enzyme immunoassays for the detection of HCV antibodies.
Journal of virological methods 2000;84(2):181-90.
2000: D Viemann; Peter Schlenke; Hans-Joerg Hammers; Holger Kirchner; Andrea Kruse
Differential expression of the B cell-restricted molecule CD22 on neonatal B lymphocytes depending upon antigen stimulation.
European journal of immunology 2000;30(2):550-9.
2000: Tobias Strunk; Stefanie Bubel; Beate Mascher; Peter Schlenke; Holger Kirchner; Klaus-Peter Wandinger
Increased numbers of CCR5+ interferon-gamma- and tumor necrosis factor-alpha-secreting T lymphocytes in multiple sclerosis patients.
Annals of neurology 2000;47(2):269-73.
2000: Burkhard Kreft; A Fischer; Sabine Krüger; K Sack; Holger Kirchner; Lothar Rink
The impaired immune response to diphtheria vaccination in elderly chronic hemodialysis patients is related to zinc deficiency.
Biogerontology 2000;1(1):61-6.
2000: Peter Schlenke; Christoph Frohn; M M Steinhardt; Holger Kirchner; Harald Klüter
Clinically relevant hypokalaemia, hypocalcaemia, and loss of hemoglobin and platelets during stem cell apheresis.
Journal of clinical apheresis 2000;15(4):230-5.
2000: Peter Schlenke; Christoph Frohn; Holger Hennig; K Weber; Jens Kisro; M Saballus; Holger Kirchner; Harald Klüter
Collection efficiencies of CD34+ progenitor cells and mononuclear cells in leukapheresis products quantified by flow cytometry and calculated on the basis of a new formula.
Vox sanguinis 2000;78(4):242-9.
1999: Harald Klüter; Stefanie Bubel; Holger Kirchner; D Wilhelm
Febrile and allergic transfusion reactions after the transfusion of white cell-poor platelet preparations.
Transfusion 1999;39(11-12):1179-84.
1999: Jürgen Krauter; Arnold Ganser; Lothar Bergmann; A Raghavachar; Dieter Hoelzer; M Lübbert; G Schlimok; Renate Arnold; Holger Kirchner; M Port; Gerhard Heil
Association between structural and numerical chromosomal aberrations in acute myeloblastic leukemia: a study by RT-PCR and FISH in 447 patients with de-novo AML.
Annals of hematology 1999;78(6):265-9.
1999: Wolfram J Jabs; M Paulsen; Hans-Joachim Wagner; Holger Kirchner; H Klüter
Analysis of Epstein-Barr virus (EBV) receptor CD21 on peripheral B lymphocytes of long-term EBV- adults.
Clinical and experimental immunology 1999;116(3):468-73.
1999: Christoph Härtel; Gregor Bein; Holger Kirchner; Harald Klüter
A human whole-blood assay for analysis of T-cell function by quantification of cytokine mRNA.
Scandinavian journal of immunology 1999;49(6):649-54.
1999: Wolfram J Jabs; C Hennig; Rainer Zawatzky; Holger Kirchner
Failure to detect antiviral activity in serum and plasma of healthy individuals displaying high activity in ELISA for IFN-alpha and IFN-beta.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999;19(5):463-9.
1999: Reinhard Hoffmann; Anke Franzke; Jan Buer; Saadettin Sel; K Oevermann; Anette Duensing; M Probst; Stefan Duensing; Holger Kirchner; Arnold Ganser; Jens Atzpodien
Prognostic impact of in vivo soluble cell adhesion molecules in metastatic renal cell carcinoma.
British journal of cancer 1999;79(11-12):1742-5.
1999: A Woywodt; Diether Ludwig; P Neustock; A Kruse; K Schwarting; Günter Jantschek; Holger Kirchner; Eduard F Stange
Mucosal cytokine expression, cellular markers and adhesion molecules in inflammatory bowel disease.
European journal of gastroenterology & hepatology 1999;11(3):267-76.
1999: Anke Franzke; Dietrich Peest; Michael Probst-Kepper; Jan Buer; Gabriele I Kirchner; Georg Brabant; Holger Kirchner; Arnold Ganser; Jens Atzpodien
Autoimmunity resulting from cytokine treatment predicts long-term survival in patients with metastatic renal cell cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(2):529-33.
1999: S Gehring; Hans Hoerauf; Horst Laqua; Holger Kirchner; Harald Klüter
Preparation of autologous platelets for the ophthalmologic treatment of macular holes.
Transfusion 1999;39(2):144-8.
1998: Hans-Joachim G Siemens; Harald Klüter; Sabine Brückner; Holger Kirchner; Hugo A Katus; T Wagner
Evaluation of two new integrated adapters for blood drawing in closed blood bag systems: influence on different molecular coagulation markers.
Transfusion medicine (Oxford, England) 1998;8(4):325-32.
1998: Peter Schlenke; Christoph Frohn; Harald Klüter; M Saballus; Hans-Joerg Hammers; S R Zajac; Holger Kirchner
Evaluation of a flow cytometric method for simultaneous leukocyte phenotyping and quantification by fluorescent microspheres.
Cytometry 1998;33(3):310-7.
1998: Jürgen Krauter; W Peter; U Pascheberg; Barbara Heinze; Lothar Bergmann; Dieter Hoelzer; M Lübbert; G Schlimok; Renate Arnold; Holger Kirchner; M Port; Arnold Ganser; Gerhard Heil
Detection of karyotypic aberrations in acute myeloblastic leukaemia: a prospective comparison between PCR/FISH and standard cytogenetics in 140 patients with de novo AML.
British journal of haematology 1998;103(1):72-8.
1998: Reinhard Hoffmann; I Müller; Karsten Neuber; S Lassmann; Jan Buer; M Probst; K Oevermann; Anke Franzke; Holger Kirchner; Arnold Ganser; Jens Atzpodien
Risk and outcome in metastatic malignant melanoma patients receiving DTIC, cisplatin, BCNU and tamoxifen followed by immunotherapy with interleukin 2 and interferon alpha2a.
British journal of cancer 1998;78(8):1076-80.
1998: Christoph Frohn; Peter Schlenke; Brigitte Ebel; C Dannenberg; Gregor Bein; Holger Kirchner
DNA typing for natural killer cell inhibiting HLA-Cw groups NK1 and NK2 by PCR-SSP.
Journal of immunological methods 1998;218(1-2):155-60.
1998: Holger Hennig; Karl Wessel; P Sondermeijer; Holger Kirchner; Klaus-Peter Wandinger
Lack of evidence for Marek's disease virus genomic sequences in leukocyte DNA from multiple sclerosis patients in Germany.
Neuroscience letters 1998;250(2):138-40.
1998: Gabriele I Kirchner; Anke Franzke; Jan Buer; W Beil; Michael Probst-Kepper; F Wittke; K Overmann; S Lassmann; Reinhard Hoffmann; Holger Kirchner; Arnold Ganser; Jens Atzpodien
Pharmacokinetics of recombinant human interleukin-2 in advanced renal cell carcinoma patients following subcutaneous application.
British journal of clinical pharmacology 1998;46(1):5-10.
1998: S Korte; Volker Arolt; M Peters; C Weitzsch; Matthias Rothermundt; Holger Kirchner
Increased serum neopterin levels in acutely ill and recovered schizophrenic patients.
Schizophrenia research 1998;32(1):63-7.
1998: Klaus-Peter Wandinger; Karl Wessel; Peter Trillenberg; N Heindl; Holger Kirchner
Effect of high-dose methylprednisolone administration on immune functions in multiple sclerosis patients.
Acta neurologica Scandinavica 1998;97(6):359-65.
1998: Lothar Rink; Irem Cakman; Holger Kirchner
Altered cytokine production in the elderly.
Mechanisms of ageing and development 1998;102(2-3):199-209.
1998: Jörg-Matthias Brand; Holger Kirchner; C Poppe; Peter Schmucker
[Cytokine release and changes in mononuclear cells in peripheral blood under the influence of general anesthesia].
Der Anaesthesist 1998;47(5):379-86.
1998: Michael Müller-Steinhardt; Holger Kirchner; Harald Klüter
Impact of storage at 22 degrees C and citrate anticoagulation on the cytokine secretion of mononuclear leukocytes.
Vox sanguinis 1998;75(1):12-7.
1998: Karin Janetzko; R Böcher; Karl Klotz; Holger Kirchner; Harald Klüter
Effects of blood donation on the physical fitness and hemorheology of healthy elderly donors.
Vox sanguinis 1998;75(1):7-11.
1998: Matthias Rothermundt; Volker Arolt; C Weitzsch; D Eckhoff; Holger Kirchner
Immunological dysfunction in schizophrenia: a systematic approach.
Neuropsychobiology 1998;37(4):186-93.
1998: L Alvarez-Ossorio; M Johannsen; R Alvarez-Ossorio; W Nicklas; Holger Kirchner; Lothar Rink
Cytokine induction by Mycoplasma arthritidis-derived superantigen (MAS), but not by TSST-1 or SEC-3, is correlated to certain HLA-DR types.
Scandinavian journal of immunology 1998;47(1):43-7.
1997: Christoph Frohn; Peter Schlenke; Holger Kirchner
The repertoire of HLA-Cw-specific NK cell receptors CD158 a/b (EB6 and GL183) in individuals with different HLA phenotypes.
Immunology 1997;92(4):567-70.
1997: Michael Müller-Steinhardt; Karin Janetzko; R Kandler; Jocelyne Flament; Holger Kirchner; Harald Klüter
Impact of various red cell concentrate preparation methods on the efficiency of prestorage white cell filtration and on red cells during storage for 42 days.
Transfusion 1997;37(11-12):1137-42.
1997: U Fagin; Ulrich Hahn; J Grötzinger; B Fleischer; D Gerlach; F Buck; Axel Wollmer; Holger Kirchner; Lothar Rink
Exclusion of bioactive contaminations in Streptococcus pyogenes erythrogenic toxin A preparations by recombinant expression in Escherichia coli.
Infection and immunity 1997;65(11):4725-33.
1997: Mathias W Hornef; Gregor Bein; D Wilhelm; Lutz Fricke; Holger Kirchner
ICAM-1, soluble-CD23, and interleukin-10 concentrations in serum in renal-transplant recipients with Epstein-Barr virus reactivation.
Clinical and diagnostic laboratory immunology 1997;4(5):545-9.
1997: Lothar Rink; W Nicklas; L Alvarez-Ossorio; U Fagin; Holger Kirchner
Microbial superantigens stimulate T cells by the superantigen bridge and independently by a cytokine pathway.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1997;17(8):489-99.
1997: Irem Cakman; Holger Kirchner; Lothar Rink
Zinc supplementation reconstitutes the production of interferon-alpha by leukocytes from elderly persons.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1997;17(8):469-72.
1997: Burkhard Kreft; M Klouche; R Kreft; Holger Kirchner; K Sack
Low efficiency of active immunization against diphtheria in chronic hemodialysis patients.
Kidney international 1997;52(1):212-6.
1997: Klaus-Peter Wandinger; Karl Wessel; P Neustock; A Siekhaus; Holger Kirchner
Diminished production of type-I interferons and interleukin-2 in patients with multiple sclerosis.
Journal of the neurological sciences 1997;149(1):87-93.
1997: Jörg-Matthias Brand; Holger Kirchner; C Poppe; Peter Schmucker
The effects of general anesthesia on human peripheral immune cell distribution and cytokine production.
Clinical immunology and immunopathology 1997;83(2):190-4.
1997: Jürgen Luhm; Holger Kirchner; Lothar Rink
One-way synergistic effect of low superantigen concentrations on lipopolysaccharide-induced cytokine production.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1997;17(4):229-38.
1997: Harald Klüter; Peter Schlenke; Michael Müller-Steinhardt; M Paulsen; Holger Kirchner
Impact of buffy coat storage on the generation of inflammatory cytokines and platelet activation.
Transfusion 1997;37(4):362-7.
1997: L Alvarez-Ossorio; M Johannsen; Martin Russlies; Holger Kirchner; Lothar Rink
HLA-dependent heterogeneous T cell response to Mycoplasma arthritidis-derived superantigen (MAS).
Medical microbiology and immunology 1997;185(4):245-51.
1997: Volker Arolt; C Weitzsch; Iris Wilke; A Nolte; M Pinnow; Matthias Rothermundt; Holger Kirchner
Production of interferon-gamma in families with multiple occurrence of schizophrenia.
Psychiatry research 1997;66(2-3):145-52.
1997: Michael Müller-Steinhardt; Karin Janetzko; Holger Kirchner; Harald Klüter
[Effect of whole blood preparation and leukocyte filtration on storage of erythrocyte concentrates over 42 days].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1997;34():53-7.
1997: Holger Hennig; Reinhard H Dennin; D Haase; Holger Kirchner
[HBV-DNA positive findings in HBsAg negative blood donors and patients].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1997;34():26-30.
1997: Harald Klüter; D Wilhelm; Stefanie Bubel; A Fiebelkorn; Holger Kirchner
[Cytokines and chemokines as inducers of nonhemolytic transfusion reactions after thrombocyte transfusion].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1997;34():100-4.
1997: Jörg-Matthias Brand; P Neustock; A Kruse; L Alvarez-Ossorio; A Schnabel; Holger Kirchner
Stimulation of whole blood cultures in patients with ankylosing spondylitis by a mitogen derived from Mycoplasma arthritidis (MAS) and other mitogens.
Rheumatology international 1997;16(5):207-11.
1996: Matthias Rothermundt; Volker Arolt; C Weitzsch; D Eckhoff; Holger Kirchner
Production of cytokines in acute schizophrenic psychosis.
Biological psychiatry 1996;40(12):1294-7.
1996: J Altstaedt; Holger Kirchner; Lothar Rink
Cytokine production of neutrophils is limited to interleukin-8.
Immunology 1996;89(4):563-8.
1996: M Deckert; Anke Franzke; Jan Buer; M Probst; Stefan Duensing; E Lopez-Haenninen; Holger Kirchner; H Poliwoda; Jens Atzpodien
Linomide and interleukin-2 in patients with advanced renal cell carcinoma.
Cancer biotherapy & radiopharmaceuticals 1996;11(5):319-24.
1996: P Anton; Holger Kirchner; Udo Jonas; Jens Atzpodien
Cytokines and tumor vaccination.
Cancer biotherapy & radiopharmaceuticals 1996;11(5):315-8.
1996: Lothar Rink; W Nicklas; Jürgen Luhm; R Kruse; Holger Kirchner
Induction of a proinflammatory cytokine network by Mycoplasma arthritidis-derived superantigen (MAS).
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1996;16(10):861-8.
1996: Nele Wellinghausen; Andra B Schromm; Ulrich Seydel; Klaus Brandenburg; Jürgen Luhm; Holger Kirchner; Lothar Rink
Zinc enhances lipopolysaccharide-induced monokine secretion by alteration of fluidity state of lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(7):3139-45.
1996: A Seidel; Volker Arolt; M Hunstiger; Lothar Rink; A Behnisch; Holger Kirchner
Major depressive disorder is associated with elevated monocyte counts.
Acta psychiatrica Scandinavica 1996;94(3):198-204.
1996: Holger Hackstein; G Jahn; Holger Kirchner; Gregor Bein
Fluorescence in situ hybridization with cosmid clones for the detection of human cytomegalovirus DNA in peripheral blood leukocytes.
Histochemistry and cell biology 1996;106(2):229-34.
1996: Nele Wellinghausen; A Fischer; Holger Kirchner; Lothar Rink
Interaction of zinc ions with human peripheral blood mononuclear cells.
Cellular immunology 1996;171(2):255-61.
1996: Harald Klüter; L Dörges; E Maass; T Wagner; H Bartels; Holger Kirchner
In-vivo evaluation of random donor platelet concentrates from pooled buffy coats.
Annals of hematology 1996;73(2):85-9.
1996: I Cakman; J Rohwer; R M Schütz; Holger Kirchner; Lothar Rink
Dysregulation between TH1 and TH2 T cell subpopulations in the elderly.
Mechanisms of ageing and development 1996;87(3):197-209.
1996: Stefanie Bubel; D Wilhelm; M Entelmann; Holger Kirchner; Harald Klüter
Chemokines in stored platelet concentrates.
Transfusion 1996;36(5):445-9.
1996: Wolfram J Jabs; Hans-Joachim Wagner; P Neustock; Harald Klüter; Holger Kirchner
Immunologic properties of Epstein-Barr virus-seronegative adults.
The Journal of infectious diseases 1996;173(5):1248-51.
1996: U Kunter; Jan Buer; M Probst; Stefan Duensing; Iris Dallmann; Jens Grosse; Holger Kirchner; E M Schluepen; Matthias Volkenandt; Arnold Ganser; Jens Atzpodien
Peripheral blood tyrosinase messenger RNA detection and survival in malignant melanoma.
Journal of the National Cancer Institute 1996;88(9):590-4.
1996: G Anastassiou; Stefan Duensing; Gustav Steinhoff; U Zorn; Jens Grosse; Iris Dallmann; Holger Kirchner; Arnold Ganser; Jens Atzpodien
Platelet endothelial cell adhesion molecule-1 (PECAM-1): a potential prognostic marker involved in leukocyte infiltration of renal cell carcinoma.
Oncology 1996;53(2):127-32.
1996: Karin Janetzko; R Böcher; K F Klotz; Holger Kirchner; Harald Klüter
[Blood donation after reaching 65 years of age].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1996;33():76-80.
1996: Holger Hackstein; K Böttcher; H Merz; Holger Kirchner; Gregor Bein
[Blood leukocytes are not a primary latent site of cytomegalovirus].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1996;33():235-40.
1996: Holger Hennig; D Haase; Holger Kirchner
[Prevalence of hepatitis C virus in blood donors and comparison of 4 different anti-HCV differentiation tests].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1996;33():231-4.
1996: Harald Klüter; K Fehlau; S Panzer; Holger Kirchner; Gregor Bein
Rapid typing for human platelet antigen systems-1, -2, -3 and -5 by PCR amplification with sequence-specific primers.
Vox sanguinis 1996;71(2):121-5.
1996: I Wilke; Volker Arolt; Matthias Rothermundt; C Weitzsch; M Hornberg; Holger Kirchner
Investigations of cytokine production in whole blood cultures of paranoid and residual schizophrenic patients.
European archives of psychiatry and clinical neuroscience 1996;246(5):279-84.
1996: Holger Hackstein; Holger Kirchner; G Jahn; Gregor Bein
The intracellular localization of human cytomegalovirus DNA in peripheral blood leukocytes during active infections by high-resolution fluorescence in situ hybridization.
Archives of virology 1996;141(7):1293-305.
1996: Lothar Rink; Jürgen Luhm; M Koester; Holger Kirchner
Induction of a cytokine network by superantigens with parallel TH1 and TH2 stimulation.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1996;16(1):41-7.
1996: A Seidel; Volker Arolt; M Hunstiger; Lothar Rink; A Behnisch; Holger Kirchner
Increased CD56+ natural killer cells and related cytokines in major depression.
Clinical immunology and immunopathology 1996;78(1):83-5.
1996: Stefan Duensing; E van den Berg-de Ruiter; S Störkel; Holger Kirchner; E L Hänninen; Jan Buer; H Poliwoda; Jens Atzpodien
Cytogenetic studies in renal cell carcinoma patients receiving low-dose recombinant interleukin-2-based immunotherapy.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1996;17(1):27-33.
1996: E Lopez Hänninen; Holger Kirchner; Jens Atzpodien
Interleukin-2 based home therapy of metastatic renal cell carcinoma: risks and benefits in 215 consecutive single institution patients.
The Journal of urology 1996;155(1):19-25.
1995: Hans-Joachim Wagner; Harald Klüter; A Kruse; Peter Bucsky; Mathias W Hornef; Holger Kirchner
Determination of the number of Epstein-Barr virus genomes in whole blood and red cell concentrates.
Transfusion medicine (Oxford, England) 1995;5(4):297-302.
1995: Harald Klüter; Peter Vieregge; H Stolze; Holger Kirchner
Defective production of interleukin-2 in patients with idiopathic Parkinson's disease.
Journal of the neurological sciences 1995;133(1-2):134-9.
1995: Hans-Joachim Wagner; Mathias W Hornef; Jaap Middeldorp; Holger Kirchner
Characteristics of viral protein expression by Epstein-Barr virus-infected B cells in peripheral blood of patients with infectious mononucleosis.
Clinical and diagnostic laboratory immunology 1995;2(6):696-9.
1995: M Klouche; A R Bradwell; D Wilhelm; Holger Kirchner
Subclass typing of IgG paraproteins by immunofixation electrophoresis.
Clinical chemistry 1995;41(10):1475-9.
1995: Mathias W Hornef; Gregor Bein; Lutz Fricke; Jürgen Steinhoff; Hans-Joachim Wagner; W Hinderer; H H Sonneborn; Holger Kirchner
Coincidence of Epstein-Barr virus reactivation, cytomegalovirus infection, and rejection episodes in renal transplant recipients.
Transplantation 1995;60(5):474-80.
1995: M Klouche; Dagmar Lühmann; Holger Kirchner
Low prevalence of diphtheria antitoxin in children and adults in northern Germany.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1995;14(8):682-5.
1995: C Driessen; K Hirv; Nele Wellinghausen; Holger Kirchner; Lothar Rink
Influence of serum on zinc, toxic shock syndrome toxin-1, and lipopolysaccharide-induced production of IFN-gamma and IL-1 beta by human mononuclear cells.
Journal of leukocyte biology 1995;57(6):904-8.
1995: Jens Atzpodien; E Lopez Hänninen; Holger Kirchner; Anke Franzke; A Körfer; Matthias Volkenandt; Stefan Duensing; A Schomburg; S Chaitchik; H Poliwoda
Chemoimmunotherapy of advanced malignant melanoma: sequential administration of subcutaneous interleukin-2 and interferon-alpha after intravenous dacarbazine and carboplatin or intravenous dacarbazine, cisplatin, carmustine and tamoxifen.
European journal of cancer (Oxford, England : 1990) 1995;31A(6):876-81.
1995: A Seidel; Volker Arolt; M Hunstiger; Lothar Rink; A Behnisch; Holger Kirchner
Cytokine production and serum proteins in depression.
Scandinavian journal of immunology 1995;41(6):534-8.
1995: M Tietze; Harald Klüter; M Troch; Holger Kirchner
Immune responsiveness in orthopedic surgery patients after transfusion of autologous or allogeneic blood.
Transfusion 1995;35(5):378-83.
1995: M Hornberg; Volker Arolt; I Wilke; A Kruse; Holger Kirchner
Production of interferons and lymphokines in leukocyte cultures of patients with schizophrenia.
Schizophrenia research 1995;15(3):237-42.
1995: Jan Buer; R Hilse; Iris Dallmann; Jens Grosse; Holger Kirchner; U Zorn; E L Hänninen; Anke Franzke; Stefan Duensing; H Poliwoda
Lymphocyte-conditioned medium in combination with interleukin-2 effectively induces antitumour autoimmunity by adoptive transfer of short activated killer (SHAK) cells.
Cytokines and molecular therapy 1995;1(1):39-46.
1995: Mathias W Hornef; Hans-Joachim Wagner; A Kruse; Holger Kirchner
Cytokine production in a whole-blood assay after Epstein-Barr virus infection in vivo.
Clinical and diagnostic laboratory immunology 1995;2(2):209-13.
1995: P Neustock; A Kruse; G Bein; S Nissen; Holger Kirchner
Failure to detect type 1 interferon production in human umbilical cord vein endothelial cells after viral exposure.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995;15(2):129-35.
1995: Jens Atzpodien; E Lopez Hänninen; Holger Kirchner; H Bodenstein; M Pfreundschuh; U Rebmann; Bernd Metzner; Hans-Jochen Illiger; G Jakse; T Niesel
Multiinstitutional home-therapy trial of recombinant human interleukin-2 and interferon alfa-2 in progressive metastatic renal cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(2):497-501.
1995: C Driessen; K Hirv; Holger Kirchner; Lothar Rink
Divergent effects of zinc on different bacterial pathogenic agents.
The Journal of infectious diseases 1995;171(2):486-9.
1995: C Driessen; K Hirv; Holger Kirchner; Lothar Rink
Zinc regulates cytokine induction by superantigens and lipopolysaccharide.
Immunology 1995;84(2):272-7.
1995: S Görg; C Niederstadt; M Klouche; PM Rob; Jürgen Steinhoff; Holger Kirchner; K Sack
[Intestinal vasculitis and glomerulonephritis in hepatitis C- associated cryoglobulinemia].
Immunität und Infektion 1995;23(1):29-31.
1995: Mathias W Hornef; Hans-Joachim Wagner; Lutz Fricke; Gregor Bein; Holger Kirchner
Immunocytochemical detection of Epstein-Barr virus antigens in peripheral B lymphocytes after renal transplantation.
Transplantation 1995;59(1):138-40.
1995: G Anastassiou; Stefan Duensing; Gustav Steinhoff; Holger Kirchner; Arnold Ganser; Jens Atzpodien
In vivo distribution of integrins in renal cell carcinoma: integrin-phenotype alteration in different degrees of tumor differentiation and VLA-2 involvement in tumor metastasis.
Cancer biotherapy 1995;10(4):287-92.
1995: D Wilhelm; Harald Klüter; M Klouche; Holger Kirchner
Impact of allergy screening for blood donors: relationship to nonhemolytic transfusion reactions.
Vox sanguinis 1995;69(3):217-21.
1995: M Meffert; A Schomburg; E L Hänninen; T Menzel; S Vocke; Iris Dallmann; Jens Grosse; Stefan Duensing; Jan Buer; Holger Kirchner
In vivo tumor necrosis factor-alpha as indicator of biologic and clinical response to low-dose SC recombinant interleukin 2.
Anticancer research 1995;15(1):127-32.
1995: J Hein; K Böttcher; R Grundmann; Holger Kirchner; Gregor Bein
Low resolution DNA typing of the HLA-B5 cross-reactive group by nested PCR-SSP.
Tissue antigens 1995;45(1):27-35.
1995: Jens Atzpodien; Holger Kirchner; Stefan Duensing; E Lopez Hänninen; Anke Franzke; Jan Buer; M Probst; P Anton; H Poliwoda
Biochemotherapy of advanced metastatic renal-cell carcinoma: results of the combination of interleukin-2, alpha-interferon, 5-fluorouracil, vinblastine, and 13-cis-retinoic acid.
World journal of urology 1995;13(3):174-7.
1995: Holger Kirchner; P Anton; Jens Atzpodien
Adjuvant treatment of locally advanced renal cancer with autologous virus-modified tumor vaccines.
World journal of urology 1995;13(3):171-3.
1995: Harald Klüter; Michael Müller-Steinhardt; S Danzer; D Wilhelm; Holger Kirchner
Cytokines in platelet concentrates prepared from pooled buffy coats.
Vox sanguinis 1995;69(1):38-43.
1994: S G Danzer; C A Campo; B Kunze; Holger Kirchner; Lothar Rink
Identification of HLA-DRB1 and HLA-DQB1 identical individuals by a cytokine-based mixed lymphocyte culture.
Lymphokine and cytokine research 1994;13(5):303-8.
1994: M Klouche; D Wilhelm; Holger Kirchner
[Cytokines, immunoglobulins, and IgG subclasses in patients with IgG plasmacytomas].
Immunität und Infektion 1994;22(4):149-51.
1994: D Wilhelm; M Klouche; S Görg; Holger Kirchner
Expression of sCD23 in atopic and nonatopic blood donors: correlation with age, total serum IgE, and allergic symptoms.
Allergy 1994;49(7):521-5.
1994: Jens Atzpodien; E Lopez Hänninen; Holger Kirchner; J Knüver-Hopf; H Poliwoda
Human antibodies to recombinant interleukin-2 in patients with hypernephroma.
Journal of interferon research 1994;14(4):177-8.
1994: Jan Buer; Holger Kirchner; A Schomburg; Andreas Schüler; M Manns; E Lopez-Hänninen; Stefan Duensing; H Poliwoda; Jens Atzpodien
Cytokine-based biotherapy of gastrointestinal tumors.
The Clinical investigator 1994;72(7):526-34.
1994: U Zorn; Iris Dallmann; Jens Grosse; Holger Kirchner; H Poliwoda; Jens Atzpodien
Soluble interleukin 2 receptors abrogate IL-2 induced activation of peripheral mononuclear cells.
Cytokine 1994;6(4):358-64.
1994: Stefan Duensing; Iris Dallmann; Jens Grosse; Jan Buer; E Lopez Hänninen; M Deckert; S Störkel; Holger Kirchner; H Poliwoda; Jens Atzpodien
Immunocytochemical detection of P-glycoprotein: initial expression correlates with survival in renal cell carcinoma patients.
Oncology 1994;51(4):309-13.
1994: A Woywodt; P Neustock; A Kruse; K Schwarting; Diether Ludwig; Eduard F Stange; Holger Kirchner
Cytokine expression in intestinal mucosal biopsies. In situ hybridisation of the mRNA for interleukin-1 beta, interleukin-6 and tumour necrosis factor-alpha in inflammatory bowel disease.
European cytokine network 1994;5(4):387-95.
1994: S G Danzer; Holger Kirchner; Lothar Rink
Cytokine interactions in human mixed lymphocyte culture.
Transplantation 1994;57(11):1638-42.
1994: M Klouche; S Görg; D Wilhelm; Holger Kirchner
[Sex and age-dependent gaps in tetanus immunization].
Deutsche medizinische Wochenschrift (1946) 1994;119(23):827-32.
1994: Hans-Joachim Wagner; Mathias W Hornef; H M Teichert; Holger Kirchner
Sex difference in the serostatus of adults to the Epstein-Barr virus.
Immunobiology 1994;190(4-5):424-9.
1994: Dörthe M Katschinski; P Neustock; Harald Klüter; Holger Kirchner
Influence of various factors on interferon-alpha production in cultures of human leukocytes.
Journal of interferon research 1994;14(3):105-10.
1994: A Schomburg; Holger Kirchner; E Lopez-Hänninen; T Menzel; P Rudolph; A Körfer; M Fenner; H Poliwoda; Jens Atzpodien
Hepatic and serologic toxicity of systemic interleukin-2 and/or interferon-alpha. Evidence of a risk-benefit advantage of subcutaneous therapy.
American journal of clinical oncology 1994;17(3):199-209.
1994: Jens Atzpodien; Holger Kirchner; E L Hänninen; T Menzel; M Deckert; Anke Franzke; A Schomburg; H Poliwoda
Treatment of metastatic colorectal cancer patients with 5-fluorouracil in combination with recombinant subcutaneous human interleukin-2 and alpha-interferon.
Oncology 1994;51(3):273-5.
1994: B St Pierre; P Neustock; U Schramm; D Wilhelm; Holger Kirchner; G Bein
Seasonal breakdown of polymerase chain reaction.
Lancet 1994;343(8898):673.
1994: Lothar Rink; W Nicklas; L Alvarez-Ossorio; M Koester; Holger Kirchner
Differential induction of tumor necrosis factor alpha in murine and human leukocytes by Mycoplasma arthritidis-derived superantigen.
Infection and immunity 1994;62(2):462-7.
1994: C Driessen; K Hirv; Lothar Rink; Holger Kirchner
Induction of cytokines by zinc ions in human peripheral blood mononuclear cells and separated monocytes.
Lymphokine and cytokine research 1994;13(1):15-20.
1994: Michael Müller-Steinhardt; Harald Klüter; Holger Kirchner
[Lymphocyte interactions in platelet concentrates from buffy coats. Determination of proliferating cells using Ki-67 antibodies].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1994;32():66-8.
1994: Harald Klüter; M Klinger; M Bauhaus; Holger Kirchner
[Effect of leukocyte contamination on storage of platelet concentrates from buffy coats].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1994;32():61-5.
1994: Hans-Joachim Wagner; Harald Klüter; A Kruse; Holger Kirchner
[Relevance of transmission of Epstein-Barr virus through blood transfusion].
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1994;32():138-41.
1994: D Wilhelm; A Fiebelkorn; S Görg; M Klouche; Harald Klüter; Holger Kirchner
Immediate-type hypersensitivity reactions after platelet transfusion.
Beiträge zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine 1994;32():448-52.
1994: Gregor Bein; D Haase; J Schult; Thomas Eiermann; Holger Kirchner
Semiautomated HLA-DQB1 typing by fluorescent dye photometry of amplified DNA on microtiter plates.
Human immunology 1994;39(1):1-8.
1994: U Zorn; Iris Dallmann; Jens Grosse; Holger Kirchner; H Poliwoda; Jens Atzpodien
Induction of cytokines and cytotoxicity against tumor cells by Newcastle disease virus.
Cancer biotherapy 1994;9(3):225-35.
1993: Jens Atzpodien; Holger Kirchner; E L Hänninen; A Körfer; M Fenner; T Menzel; M Deckert; Anke Franzke; U Jonas; H Poliwoda
European studies of interleukin-2 in metastatic renal cell carcinoma.
Seminars in oncology 1993;20(6 Suppl 9):22-6.
1993: M Ackermann; Holger Kirchner; Jens Atzpodien
Low dose megestrol acetate can abrogate cachexia in advanced tumor patients receiving systemic interferon-alpha and/or interleukin-2 based antineoplastic therapy.
Anti-cancer drugs 1993;4(5):585-7.
1993: D Wilhelm; M Klouche; A Fiebelkorn; S Görg; Harald Klüter; Holger Kirchner
Non-haemolytic transfusion reactions after platelet substitution.
Lancet 1993;342(8867):364.
1993: J Sindermann; A Kruse; H J Frercks; R M Schütz; Holger Kirchner
Investigations of the lymphokine system in elderly individuals.
Mechanisms of ageing and development 1993;70(1-2):149-59.
1993: A Bitsch; Holger Kirchner; Reinhard H Dennin; J Hoyer; Lutz Fricke; Jürgen Steinhoff; K Sack; Gregor Bein
The long persistence of CMV DNA in the blood of renal transplant patients after recovery from CMV infection.
Transplantation 1993;56(1):108-13.
1993: P Neustock; Jörg-Matthias Brand; A Kruse; Holger Kirchner
Cytokine production of the human monocytic cell line Mono Mac 6 in comparison to mature monocytes in peripheral blood mononuclear cells.
Immunobiology 1993;188(3):293-302.
1993: A Kruse; P Neustock; M Reuter; Holger Kirchner
T-cell surface molecule expression and interferon-gamma production in human cord blood.
Journal of interferon research 1993;13(3):221-5.
1993: A Bitsch; Gregor Bein; J Hoyer; Holger Kirchner
[Diagnosis of cytomegalovirus infections in immunosuppressed patients: the role of PCR].
Immunität und Infektion 1993;21 Suppl 1():51-2.
1993: P Neustock; A Kruse; S Bock; B St Pierre; Holger Kirchner
Deficient interferon-alpha response of newborns in comparison to adults.
Lymphokine and cytokine research 1993;12(2):109-14.
1993: S Görg; M Klouche; D Wilhelm; Holger Kirchner
[Interferon alpha antibodies show no cross reactions with typical autoantibodies].
Immunität und Infektion 1993;21 Suppl 1():54-6.
1993: A Bitsch; Holger Kirchner; R Dupke; Gregor Bein
Cytomegalovirus transcripts in peripheral blood leukocytes of actively infected transplant patients detected by reverse transcription-polymerase chain reaction.
The Journal of infectious diseases 1993;167(3):740-3.
1993: J O Funk; A Kruse; P Neustock; Holger Kirchner
Helium-neon laser irradiation induces effects on cytokine production at the protein and the mRNA level.
Experimental dermatology 1993;2(2):75-83.
1993: A Schomburg; Holger Kirchner; Jens Atzpodien
Renal, metabolic, and hemodynamic side-effects of interleukin-2 and/or interferon alpha: evidence of a risk/benefit advantage of subcutaneous therapy.
Journal of cancer research and clinical oncology 1993;119(12):745-55.
1993: Gregor Bein; A Bitsch; J Hoyer; Jürgen Steinhoff; Lutz Fricke; H Machnik; Reinhard H Dennin; Holger Kirchner
A longitudinal prospective study of cytomegalovirus pp65 antigenemia in renal transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation 1993;6(4):185-90.
1993: A Schomburg; Holger Kirchner; Jens Atzpodien
Hematotoxicity of interleukin-2 in man: clinical effects and comparison of various treatment regimens.
Acta haematologica 1993;89(3):119-31.
1993: R Gläser; Thomas Eiermann; Lutz Fricke; Holger Kirchner; Gregor Bein
HLA DNA preorgan retrieval donor typing in renal transplantation.
Vox sanguinis 1993;65(4):300-2.
1993: Jens Atzpodien; Holger Kirchner; A Körfer; M Hadam; A Schomburg; T Menzel; M Deckert; Anke Franzke; Matthias Volkenandt; Iris Dallmann
Expansion of peripheral blood natural killer cells correlates with clinical outcome in cancer patients receiving recombinant subcutaneous interleukin-2 and interferon-alpha-2.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1993;14(6):354-9.
1993: Jens Atzpodien; Holger Kirchner; E L Hänninen; M Deckert; M Fenner; H Poliwoda
Interleukin-2 in combination with interferon-alpha and 5-fluorouracil for metastatic renal cell cancer.
European journal of cancer (Oxford, England : 1990) 1993;29A Suppl 5():S6-8.
1993: D Wilhelm; Holger Kirchner
T cells and their role in allergies.
Experimental and clinical immunogenetics 1993;10(4):208-18.
1993: E Lopez Hanninen; M Fenner; Holger Kirchner; M Deckert; Stefan Duensing; T Menzel; H Poliwoda; Jens Atzpodien
Limited efficacy of interferon-alpha and vinblastine as second line biochemotherapy regimen in patients with progressive metastatic renal cell carcinoma.
Cancer biotherapy 1993;8(4):301-6.
1993: Jens Atzpodien; Holger Kirchner; P de Mulder; H Bodenstein; T Oliver; P A Palmer; C R Franks; H Poliwoda
Subcutaneous recombinant interleukin-2 and alpha-interferon in patients with advanced renal cell carcinoma: results of a multicenter Phase II Study.
Cancer biotherapy 1993;8(4):289-300.
1993: T Menzel; A Schomburg; A Körfer; M Hadam; M Meffert; Iris Dallmann; S Casper; Holger Kirchner; H Poliwoda; Jens Atzpodien
Clinical and preclinical evaluation of recombinant PEG-IL-2 in human.
Cancer biotherapy 1993;8(3):199-212.
1993: P A Palmer; Jens Atzpodien; T Philip; Sylvie Negrier; Holger Kirchner; H Von der Maase; Poul F Geertsen; P Evers; E Loriaux; R Oskam
A comparison of 2 modes of administration of recombinant interleukin-2: continuous intravenous infusion alone versus subcutaneous administration plus interferon alpha in patients with advanced renal cell carcinoma.
Cancer biotherapy 1993;8(2):123-36.
1993: C Schneekloth; A Körfer; M Hadam; E Lopez Hänninen; T Menzel; A Schomburg; Iris Dallmann; Holger Kirchner; H Poliwoda; Jens Atzpodien
Low-dose interleukin-2 in combination with interferon-alpha effectively modulates biological response in vivo.
Acta haematologica 1993;89(1):13-21.
1993: A Schomburg; Holger Kirchner; M Fenner; T Menzel; H Poliwoda; Jens Atzpodien
Lack of therapeutic efficacy of tamoxifen in advanced renal cell carcinoma.
European journal of cancer (Oxford, England : 1990) 1993;29A(5):737-40.
1992: Gregor Bein; R Gläser; Thomas Eiermann; J Hoyer; D Haase; Holger Kirchner
Molecular matching in renal transplantation.
Transplantation proceedings 1992;24(6):2475-7.
1992: Stefan Duensing; M Hadam; A Körfer; A Schomburg; T Menzel; Jens Grosse; Holger Kirchner; H Poliwoda; Jens Atzpodien
Pretreatment natural killer antigen density correlates to clinical response in tumor patients receiving long-term subcutaneous recombinant interleukin-2 and recombinant interferon-alpha.
Molecular biotherapy 1992;4(4):170-3.
1992: Jörg-Matthias Brand; Holger Kirchner; P Neustock; A Kruse
Induction of cytokines in human whole blood cultures by a mitogen derived from Mycoplasma arthritidis and by staphylococcal enterotoxin B.
Immunobiology 1992;186(3-4):246-53.
1992: H J Wagner; Gregor Bein; A Bitsch; Holger Kirchner
Detection and quantification of latently infected B lymphocytes in Epstein-Barr virus-seropositive, healthy individuals by polymerase chain reaction.
Journal of clinical microbiology 1992;30(11):2826-9.
1992: A Bitsch; Holger Kirchner; R Dupke; Gregor Bein
Failure to detect human cytomegalovirus DNA in peripheral blood leukocytes of healthy blood donors by the polymerase chain reaction.
Transfusion 1992;32(7):612-7.
1992: A Schomburg; T Menzel; M Hadam; Stefan Duensing; A Körfer; Holger Kirchner; H Poliwoda; Jens Atzpodien
Biologic and therapeutic efficacy of mafosfamide in patients with metastatic renal cell carcinoma.
Molecular biotherapy 1992;4(2):58-65.
1992: P A Palmer; J Vinke; T Philip; Sylvie Negrier; Jens Atzpodien; Holger Kirchner; R Oskam; C R Franks
Prognostic factors for survival in patients with advanced renal cell carcinoma treated with recombinant interleukin-2.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1992;3(6):475-80.
1992: A Schomburg; T Menzel; A Körfer; G Heer; Iris Dallmann; Holger Kirchner; H Poliwoda; Jens Atzpodien
In vivo and ex vivo antitumor activity in patients receiving low-dose subcutaneous recombinant interleukin-2.
Natural immunity 1992;11(3):133-43.
1992: I Rutenfranz; A Kruse; L Rink; Björn E. Wenzel; H Arnholdt; Holger Kirchner
In situ hybridization of the mRNA for interferon-gamma, interferon-alpha E, interferon-beta, interleukin-1 beta and interleukin-6 and characterization of infiltrating cells in thyroid tissues.
Journal of immunological methods 1992;148(1-2):233-42.
1992: Lothar Rink; A Kruse; W Nicklas; J Hoyer; Holger Kirchner
Induction of cytokines in human peripheral blood and spleen cells by the Mycoplasma arthritidis-derived superantigen.
Lymphokine and cytokine research 1992;11(2):105-8.
1992: A Kruse; L Rink; I Rutenfranz; B Kolanczyk; Holger Kirchner
Interferon and lymphokine production by human placental and cord blood cells.
Journal of interferon research 1992;12(2):113-7.
1992: Gregor Bein; R Gläser; Holger Kirchner
Rapid HLA-DRB1 genotyping by nested PCR amplification.
Tissue antigens 1992;39(2):68-73.
1992: Lothar Rink; Holger Kirchner
Mycoplasma arthritidis-derived superantigen.
Chemical immunology 1992;55():137-45.
1992: Michael Müller-Steinhardt; Harald Klüter; Holger Kirchner
[Differentiation of leukocytes in thrombocyte concentrates by APAAP staining].
Beiträge zur Infusionstherapie = Contributions to infusion therapy 1992;30():127-30.
1991: E L Hänninen; A Körfer; M Hadam; C Schneekloth; Iris Dallmann; T Menzel; Holger Kirchner; H Poliwoda; Jens Atzpodien
Biological monitoring of low-dose interleukin 2 in humans: soluble interleukin 2 receptors, cytokines, and cell surface phenotypes.
Cancer research 1991;51(23 Pt 1):6312-6.
1991: Jens Atzpodien; H Poliwoda; Holger Kirchner
alpha-Interferon and interleukin-2 in renal cell carcinoma: studies in nonhospitalized patients.
Seminars in oncology 1991;18(5 Suppl 7):108-12.
1991: I Rutenfranz; A Kruse; Holger Kirchner
In situ hybridization of interferon-gamma producing peripheral blood mononuclear cells.
Scandinavian journal of immunology 1991;34(2):169-78.
1991: Jens Atzpodien; A Körfer; M Hadam; A Schomburg; T Menzel; Iris Dallmann; H Poliwoda; Holger Kirchner
Diminished expression of interleukin-2 receptors in vivo after prior chemotherapy in advanced cancer patients receiving recombinant interleukin-2.
Molecular biotherapy 1991;3(2):60-2.
1991: Holger Kirchner; A Körfer; P Evers; M M Szamel; J Knüver-Hopf; Harald Mohr; C R Franks; U Pohl; K Resch; M Hadam
The development of neutralizing antibodies in a patient receiving subcutaneous recombinant and natural interleukin-2.
Cancer 1991;67(7):1862-4.
1991: Gregor Bein; A Bitsch; J Hoyer; Holger Kirchner
The detection of human cytomegalovirus immediate early antigen in peripheral blood leucocytes.
Journal of immunological methods 1991;137(2):175-80.
1991: Jens Atzpodien; Holger Kirchner
The out-patient use of recombinant human interleukin-2 and interferon alfa-2b in advanced malignancies.
European journal of cancer (Oxford, England : 1990) 1991;27 Suppl 4():S88-91; discussion S92.
1990: Holger Kirchner; A Körfer; P A Palmer; P Evers; W De Riese; J Knüver-Hopf; M Hadam; U Goldman; C R Franks; H Poliwoda
Subcutaneous interleukin-2 and interferon-alpha 2b in patients with metastatic renal cell cancer: the German outpatient experience.
Molecular biotherapy 1990;2(3):145-54.
1990: I Rutenfranz; A Bauer; Holger Kirchner
Interferon gamma encapsulated into liposomes enhances the activity of monocytes and natural killer cells and has antiproliferative effects on tumor cells in vitro.
Blut 1990;61(1):30-7.
1990: I Rutenfranz; A Bauer; Holger Kirchner
Pharmacokinetic study of liposome-encapsulated human interferon-gamma after intravenous and intramuscular injection in mice.
Journal of interferon research 1990;10(3):337-41.
1990: Jens Atzpodien; Holger Kirchner
Cancer, cytokines, and cytotoxic cells: interleukin-2 in the immunotherapy of human neoplasms.
Klinische Wochenschrift 1990;68(1):1-11.
1990: H Link; J Seidel; M Stoll; Holger Kirchner; C Linderkamp; Mathias Freund; P Bucsky; K Welte; Hansjörg Riehm; S Burdach
Regeneration of granulopoiesis with recombinant human granulocyte-macrophage colony-stimulating factor after bone marrow transplantation.
Haematology and blood transfusion 1990;33():741-6.
1989: Jens Atzpodien; C Bührer; S C Gulati; David Wisniewski; S Oz; Holger Kirchner; Thomas Benter; H Poliwoda; Karl Welte; Bayard Clarkson
Induction of nonspecific cell-mediated cytotoxicity: a multisignal event and its cellular regulation.
Haematology and blood transfusion 1989;32():273-80.
1989: A Körfer; Holger Kirchner; C Schneekloth; C Bührer; David Wisniewski; S Gulati; Bayard Clarkson; R Knowles; H Poliwoda; Jens Atzpodien
Immunophenotypic demonstration of two natural killer surface markers, H25 and H366, on fresh human leukemic cells.
Acta haematologica 1989;82(4):193-6.
1988: H Link; Mathias Freund; Holger Kirchner; M Stoll; H Schmid; P Bucsky; J Seidel; G Schulz; Reinhold E Schmidt; Hansjörg Riehm
Recombinant human granulocyte-macrophage colony stimulating factor (rh GM-CSF) after bone marrow transplantation.
Behring Institute Mitteilungen 1988;(83):313-9.