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Thomas Kirchner

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Stefan Boeck; Rosalind Egg; Clara Goritschan; Michael Haas; Andreas Jung; Thomas Kirchner; Rüdiger P Laubender; Dominik P Modest; Jens Neumann; Steffen Ormanns; Volker Heinemann
KRAS mutation status is not predictive for objective response to anti-EGFR treatment with erlotinib in patients with advanced pancreatic cancer.
Stefan Boeck; M R Clemens; R Egg; L Fischer von Weikersthal; Thomas Gauler; M Geissler; C Goritschan; T F Greten; Andreas Jung; Thomas Kirchner; S Klein; G Kojouharoff; R P Laubender; U Mansmann; Angela Märten; J Neumann; Ursula Vehling-Kaiser; C Winkelmann; M Barner; Volker Heinemann
EGFR pathway biomarkers in erlotinib-treated patients with advanced pancreatic cancer: translational results from the randomised, crossover phase 3 trial AIO-PK0104.
Sebastian Stintzing; Andreas Wollenberg; Clemens Giessen; Andreas Jung; Christine Kapaun; Thomas Kirchner; Rüdiger Paul Laubender; Dominik Paul Modest; Nicolas Moosmann; Jens Neumann; Volker Heinemann
Prognostic value of cetuximab-related skin toxicity in metastatic colorectal cancer patients and its correlation with parameters of the epidermal growth factor receptor signal transduction pathway: results from a randomized trial of the GERMAN AIO CRC Study Group.

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2013: Stefan Boeck; Rosalind Egg; Clara Goritschan; Michael Haas; Andreas Jung; Thomas Kirchner; Rüdiger P Laubender; Dominik P Modest; Jens Neumann; Steffen Ormanns; Volker Heinemann
KRAS mutation status is not predictive for objective response to anti-EGFR treatment with erlotinib in patients with advanced pancreatic cancer.
Journal of gastroenterology 2013;48(4):544-8.
2013: Stefan Boeck; M R Clemens; R Egg; L Fischer von Weikersthal; Thomas Gauler; M Geissler; C Goritschan; T F Greten; Andreas Jung; Thomas Kirchner; S Klein; G Kojouharoff; R P Laubender; U Mansmann; Angela Märten; J Neumann; Ursula Vehling-Kaiser; C Winkelmann; M Barner; Volker Heinemann
EGFR pathway biomarkers in erlotinib-treated patients with advanced pancreatic cancer: translational results from the randomised, crossover phase 3 trial AIO-PK0104.
British journal of cancer 2013;108(2):469-76.
2013: Sebastian Stintzing; Andreas Wollenberg; Clemens Giessen; Andreas Jung; Christine Kapaun; Thomas Kirchner; Rüdiger Paul Laubender; Dominik Paul Modest; Nicolas Moosmann; Jens Neumann; Volker Heinemann
Prognostic value of cetuximab-related skin toxicity in metastatic colorectal cancer patients and its correlation with parameters of the epidermal growth factor receptor signal transduction pathway: results from a randomized trial of the GERMAN AIO CRC Study Group.
International journal of cancer. Journal international du cancer 2013;132(1):236-45.
2012: Lydia Kriegl; Thomas Kirchner; Michael Vieth; Antje Menssen
Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer.
Oncotarget 2012;3(10):1182-93.
2012: Stefanie Jaitner; Thomas Brabletz; Hermann Herbst; Elke Hiendlmeyer; Thomas Kirchner; Jana A Reiche; Achim J Schäffauer; Andreas Jung
Human telomerase reverse transcriptase (hTERT) is a target gene of β-catenin in human colorectal tumors.
Cell cycle (Georgetown, Tex.) 2012;11(17):3331-8.
2012: Pamela Zengel; Gerald Assmann; Andreas Jung; Thomas Kirchner; Martin Mollenhauer; Karl Sotlar; Stephan Ihrler
Cancer of unknown primary originating from oropharyngeal carcinomas are strongly correlated to HPV positivity.
Virchows Archiv : an international journal of pathology 2012;461(3):283-90.
2012: Claus Schäfer; Hendrik Seeliger; Andreas Ziesch; Gerald Assmann; Dominik C Bader; Christiane Bruns; Denise Buchner; Enrico N De Toni; Burkhard Göke; Yang Guo; Andreas Jung; Thomas Kirchner; Rüdiger P Laubender; Stephanie Ochs; Andreas Palagyi; Eike Gallmeier
Heat shock protein 27 as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma.
Journal of cellular and molecular medicine 2012;16(8):1776-91.
2012: Christoph Walz; Marion Subklewe; Michael Flaig; Hans-Peter Horny; Thomas Kirchner; Andreas Reiter; Karl Sotlar
Advanced systemic mastocytosis as a mimicker of metastatic clear cell renal cell carcinoma.
Leukemia research 2012;36(6):799-801.
2012: Christoph Weiler; Pamela Zengel; Johannes Zenk; Abbas Agaimy; Thomas Kirchner; Stephan Ihrler
Nonsebaceous lymphadenoma of salivary glands: proposed development from intraparotid lymph nodes and risk of misdiagnosis.
Virchows Archiv : an international journal of pathology 2012;460(5):467-72.
2012: Claudia Schuster; Kai Tran; Claudia Wolff; Karl-Friedrich Becker; Daniela Berg; Claudius Faber; Heinz Höfler; Thomas Kirchner; Sibylle Liebmann; Katharina Malinowsky; Jens Neumann; Simone Reu; Christina Schott; Falk Hlubek
Antibody validation by combining immunohistochemistry and protein extraction from formalin-fixed paraffin-embedded tissues.
Histopathology 2012;60(6B):E37-50.
2012: David Horst; Thomas Kirchner; Teppei Morikawa; Shuji Ogino; Justina Chen; Ramesh A Shivdasani
Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling.
Cancer research 2012;72(6):1547-56.
2012: Abdelhamid Beji; Jutta Engel; David Horst; Thomas Kirchner; Axel Ullrich
Toward the prognostic significance and therapeutic potential of HER3 receptor tyrosine kinase in human colon cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(4):956-68.
2012: J Neumann; S Reu; Thomas Kirchner
[Prognostic marker profiles for risk of distant metastases in colorectal cancer].
Der Pathologe 2012;33(1):39-44.
2012: S Reu; J Neumann; Thomas Kirchner
[Gastrointestinal mixed adenoneuroendocrine carcinomas. An attempt at classification of mixed cancers].
Der Pathologe 2012;33(1):31-8.
2012: Thomas Kirchner
[Gastrointestinal tumors].
Der Pathologe 2012;33(1):4.
2012: Jens Neumann; Lydia Kriegl; Susanne Maatz; Jutta Engel; David Horst; Andreas Jung; Thomas Kirchner
A simple immunohistochemical algorithm predicts the risk of distant metastases in right-sided colon cancer.
Histopathology 2012;60(3):416-26.
2012: S Reu; J Neumann; Thomas Kirchner
[Mucinous neoplasms of the vermiform appendix, Pseudomyxoma peritonei, and the new WHO classification].
Der Pathologe 2012;33(1):24-30.
2012: Tobias Vogler; Jutta Engel; David Horst; Thomas Kirchner; Lydia Kriegl; Sabine Sagebiel; Achim J Schäffauer; Andreas Jung
The expression pattern of aldehyde dehydrogenase 1 (ALDH1) is an independent prognostic marker for low survival in colorectal tumors.
Experimental and molecular pathology 2012;92(1):111-7.
2012: Clemens Giessen; Anno Graser; Volker Heinemann; Bruno Huber; Thomas Kirchner; Doris Mayr; Johannes R Bogner; Dorit Di Gioia; Hans Roland Duerr; Roswitha Forstpointner; Andreas Rosenwald; Bettina Seppi; Helmut Ostermann
Primary effusion lymphoma (PEL) without effusion: a patient case report of a PEL solid variant.
Journal of clinical pathology 2012;65(2):189-90.
2012: Lydia Kriegl; Antonia Rizzani; Eike Gallmeier; Alexander L Gerbes; Burkhard Göke; Heiko Hermeking; David Horst; Rene Jackstadt; Andreas Jung; Thomas Kirchner; Enrico N De Toni
Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer.
PloS one 2012;7(12):e51654.
2011: Christoph Weiler; Pamela Zengel; Orlando Guntinas-Lichius; John D Harrison; Thomas Kirchner; Stephan Schwarz; Jacqueline E van der Wal; Stephan Ihrler
Carcinoma ex pleomorphic adenoma with special reference to the prognostic significance of histological progression: a clinicopathological investigation of 41 cases.
Histopathology 2011;59(4):741-50.
2011: Dominik P Modest; Jens Neumann; Christoph Schulz; Hans-Joachim Stemmler; Sebastian Stintzing; Philipp Aubele; Stefan Boeck; Clemens Giessen; Michael Haas; Andreas Jung; Thomas Kirchner; Ruediger P Laubender; Volker Heinemann
Clinical characterization of patients with metastatic colorectal cancer depending on the KRAS status.
Anti-cancer drugs 2011;22(9):913-8.
2011: Ossia M Eichhoff; Laurence Denat; Reinhard Dummer; Thomas Kirchner; Lydia Kriegl; Lionel Larue; Ashani T Weeraratna; Daniel S Widmer; Mai Xu; Marie C Zipser; Keith Hoek
Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching.
Pigment cell & melanoma research 2011;24(4):631-42.
2011: Lydia Kriegl; Jens Neumann; Simone Reu; Michael Vieth; Florian R Greten; Andreas Jung; Thomas Kirchner
Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011;24(7):1015-22.
2011: C Faber; D Horst; Falk Hlubek; Thomas Kirchner
Overexpression of Dicer predicts poor survival in colorectal cancer.
European journal of cancer (Oxford, England : 1990) 2011;47(9):1414-9.
2011: Jens Neumann; Thomas Kirchner; Lydia Kriegl; Raquel Mejias Luque; Fiorina Bahr; Jutta Engel; Markus Gerhard; David Horst; Andreas Jung
SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer.
BMC cancer 2011;11():518.
2011: Claudia Schuster; Jan Budczies; Claudius Faber; Thomas Kirchner; Falk Hlubek
MicroRNA expression profiling of specific cells in complex archival tissue stained by immunohistochemistry.
Laboratory investigation; a journal of technical methods and pathology 2011;91(1):157-65.
2010: Jutta Maria Nagel; Lydia Kriegl; David Horst; Jutta Engel; Shiva Gautam; Christos S Mantzoros; Thomas Kirchner; Burkhard Göke; Frank T Kolligs
γ-Catenin is an independent prognostic marker in early stage colorectal cancer.
International journal of colorectal disease 2010;25(11):1301-9.
2010: Andreas Jung; S Jaitner; A J Schäffauer; Thomas Kirchner
[mRNA quantification. The next challenge in routine diagnostics].
Der Pathologe 2010;31 Suppl 2():280-4.
2010: Stephan Ihrler; Christian Rath; Pamela Zengel; Thomas Kirchner; John D Harrison; Christoph Weiler
Pathogenesis of sialadenosis: possible role of functionally deficient myoepithelial cells.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2010;110(2):218-23.
2010: Eugenia Lesina; Petra Dames; Andreas Flemmer; Kerstin Hajek; Thomas Kirchner; Iris Bittmann; Carsten Rudolph
CpG-free plasmid DNA prevents deterioration of pulmonary function in mice.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2010;74(3):427-34.
2010: Thomas Kirchner; Andreas Jung
[Pathological diagnosis for individualized therapy of colorectal cancer].
Der Pathologe 2010;31(1):16-21.
2010: Lydia Kriegl; David Horst; Jana Anni Reiche; Jutta Engel; Thomas Kirchner; Andreas Jung
LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer.
Journal of translational medicine 2010;8():123.
2010: Silvio K Scheel; Marc Porzner; Sabine Pfeiffer; Steffen Ormanns; Thomas Kirchner; Andreas Jung
Mutations in the WTX-gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers.
BMC cancer 2010;10():413.
2009: Doris Mayr; Sibylle Heim; Kerstin Weyrauch; Evelyn Zeindl-Eberhart; Anne Kunz; Jutta Engel; Thomas Kirchner
Chromogenic in situ hybridization for Her-2/neu-oncogene in breast cancer: comparison of a new dual-colour chromogenic in situ hybridization with immunohistochemistry and fluorescence in situ hybridization.
Histopathology 2009;55(6):716-23.
2009: David Horst; Silvio K Scheel; Sibylle Liebmann; Jens Neumann; Susanne Maatz; Thomas Kirchner; Andreas Jung
The cancer stem cell marker CD133 has high prognostic impact but unknown functional relevance for the metastasis of human colon cancer.
The Journal of pathology 2009;219(4):427-34.
2009: Stephan Ihrler; S Schwarz; P Zengel; O Guntinas-Lichius; Thomas Kirchner; Christoph Weiler
[Pleomorphic adenoma: pitfalls and clinicopathological forms of progression].
Der Pathologe 2009;30(6):446-56.
2009: David Horst; Jan Budczies; Thomas Brabletz; Thomas Kirchner; Falk Hlubek
Invasion associated up-regulation of nuclear factor kappaB target genes in colorectal cancer.
Cancer 2009;115(21):4946-58.
2009: David Horst; Lydia Kriegl; Jutta Engel; Thomas Kirchner; Andreas Jung
Prognostic significance of the cancer stem cell markers CD133, CD44, and CD166 in colorectal cancer.
Cancer investigation 2009;27(8):844-50.
2009: David Horst; Lydia Kriegl; Jutta Engel; Andreas Jung; Thomas Kirchner
CD133 and nuclear beta-catenin: the marker combination to detect high risk cases of low stage colorectal cancer.
European journal of cancer (Oxford, England : 1990) 2009;45(11):2034-40.
2009: David Horst; Simone Reu; Lydia Kriegl; Jutta Engel; Thomas Kirchner; Andreas Jung
The intratumoral distribution of nuclear beta-catenin is a prognostic marker in colon cancer.
Cancer 2009;115(10):2063-70.
2009: Volker Heinemann; Sebastian Stintzing; Thomas Kirchner; Stefan Boeck; Andreas Jung
Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR.
Cancer treatment reviews 2009;35(3):262-71.
2009: Claudius Faber; Thomas Kirchner; Falk Hlubek
The impact of microRNAs on colorectal cancer.
Virchows Archiv : an international journal of pathology 2009;454(4):359-67.
2009: Jens Neumann; Evelyn Zeindl-Eberhart; Thomas Kirchner; Andreas Jung
Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancer.
Pathology, research and practice 2009;205(12):858-62.
2009: Christoph Weiler; Simone Reu; Pamela Zengel; Thomas Kirchner; Stephan Ihrler
Obligate basal cell component in salivary oncocytoma facilitates distinction from acinic cell carcinoma.
Pathology, research and practice 2009;205(12):838-42.
2009: Stella Wassermann; Silvio Scheel; Elke Hiendlmeyer; Richard Palmqvist; David Horst; Falk Hlubek; Angela Haynl; Lydia Kriegl; Simone Reu; Susanne Merkel; Thomas Brabletz; Thomas Kirchner; Andreas Jung
p16INK4a is a beta-catenin target gene and indicates low survival in human colorectal tumors.
Gastroenterology 2009;136(1):196-205.e2.
2008: Thomas Kirchner; S Reu
[Development of molecular-pathologic entities of colorectal cancer].
Der Pathologe 2008;29 Suppl 2():264-9.
2008: D Horst; L Kriegl; J Engel; Thomas Kirchner; Andreas Jung
CD133 expression is an independent prognostic marker for low survival in colorectal cancer.
British journal of cancer 2008;99(8):1285-9.
2008: Roland S Croner; Thomas Förtsch; Wolfgang M Brückl; Franz Rödel; Claus Rödel; Thomas Papadopoulos; Thomas Brabletz; Thomas Kirchner; Martin Sachs; Jürgen Behrens; Ludger Klein-Hitpass; Michael Stürzl; Werner Hohenberger; berthold lausen
Molecular signature for lymphatic metastasis in colorectal carcinomas.
Annals of surgery 2008;247(5):803-10.
2008: Simone Spaderna; Otto Schmalhofer; Mandy Wahlbuhl; Arno Dimmler; Katja Bauer; Aneesa Sultan; Falk Hlubek; Andreas Jung; Dennis Strand; Andreas Eger; Thomas Kirchner; Jürgen Behrens; Thomas Brabletz
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer.
Cancer research 2008;68(2):537-44.
2007: Falk Hlubek; Thomas Brabletz; Jan Budczies; Sabine Pfeiffer; Andreas Jung; Thomas Kirchner
Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer.
International journal of cancer. Journal international du cancer 2007;121(9):1941-8.
2007: Falk Hlubek; Simone Spaderna; Otto Schmalhofer; Andreas Jung; Thomas Kirchner; Thomas Brabletz
Wnt/FZD signaling and colorectal cancer morphogenesis.
Frontiers in bioscience : a journal and virtual library 2007;12():458-70.
2006: Simone Spaderna; Otto Schmalhofer; Falk Hlubek; Geert Berx; Andreas Eger; Susanne Merkel; Andreas Jung; Thomas Kirchner; Thomas Brabletz
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer.
Gastroenterology 2006;131(3):830-40.
2006: Falk Hlubek; S Pfeiffer; Jan Budczies; Simone Spaderna; Andreas Jung; Thomas Kirchner; Thomas Brabletz
Securin (hPTTG1) expression is regulated by beta-catenin/TCF in human colorectal carcinoma.
British journal of cancer 2006;94(11):1672-7.
2005: Katharina Beiter; Elke Hiendlmeyer; Thomas Brabletz; Falk Hlubek; Angela Haynl; Claudia Knoll; Thomas Kirchner; Andreas Jung
beta-Catenin regulates the expression of tenascin-C in human colorectal tumors.
Oncogene 2005;24(55):8200-4.
2005: Thomas Brabletz; Andreas Jung; Simone Spaderna; Falk Hlubek; Thomas Kirchner
Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression.
Nature reviews. Cancer 2005;5(9):744-9.
2005: Tilman Rau; Arno Dimmler; Manuela Häfner; Thomas Brabletz; Thomas Kirchner; Gerhard Faller
Aberrant expression of TTF-1 and forkhead factor HFH-4 in atrophic gastritis and ciliated metaplasia suggests gastric broncho-pulmonary transdetermination.
The Journal of pathology 2005;206(4):383-7.
2005: Roland S Croner; Thomas Foertsch; Wolfgang M Brueckl; Klaus Guenther; Renate Siebenhaar; Christian Stremmel; Klaus E Matzel; Thomas Papadopoulos; Thomas Kirchner; Jürgen Behrens; Ludger Klein-Hitpass; Michael Stuerzl; Werner Hohenberger; Bertram Reingruber
Common denominator genes that distinguish colorectal carcinoma from normal mucosa.
International journal of colorectal disease 2005;20(4):353-62.
2005: Wolfgang M Brueckl; Jens Grombach; Axel Wein; Stefan Ruckert; Marc Porzner; Wolfgang Dietmaier; Petra Rümmele; Roland S Croner; Frank Boxberger; Thomas Kirchner; Werner Hohenberger; Eckhart Hahn; Andreas Jung
Alterations in the tissue inhibitor of metalloproteinase-3 (TIMP-3) are found frequently in human colorectal tumours displaying either microsatellite stability (MSS) or instability (MSI).
Cancer letters 2005;223(1):137-42.
2005: Wolfgang M Brueckl; Wolfgang G Ballhausen; Thomas Förtsch; Klaus Günther; Wolfgang Fiedler; Bernhard Gentner; Roland S Croner; Frank Boxberger; Thomas Kirchner; Eckhart Hahn; Werner Hohenberger; Axel Wein
Genetic testing for germline mutations of the APC gene in patients with apparently sporadic desmoid tumors but a family history of colorectal carcinoma.
Diseases of the colon and rectum 2005;48(6):1275-81.
2005: Sebastian Stintzing; Peter U Heuschmann; Letterio Barbera; Matthias Ocker; Andreas Jung; Thomas Kirchner; Daniel Neureiter
Overexpression of MMP9 and tissue factor in unstable carotid plaques associated with Chlamydia pneumoniae, inflammation, and apoptosis.
Annals of vascular surgery 2005;19(3):310-9.
2005: E Wolf; H Harms; J Winkler; U Reulbach; Thomas Kirchner; G Niedobitek; I Baumann
Terminal deoxynucleotidyl transferase-positive cells in trephine biopsies following bone marrow or peripheral stem cell transplantation reflect vigorous B-cell generation.
Histopathology 2005;46(4):442-50.
2005: Daniel Neureiter; Steffen Zopf; Arno Dimmler; Sebastian Stintzing; Eckhart Hahn; Thomas Kirchner; Christoph Herold; Matthias Ocker
Different capabilities of morphological pattern formation and its association with the expression of differentiation markers in a xenograft model of human pancreatic cancer cell lines.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2005;5(4-5):387-97.
2005: Thomas Brabletz; Falk Hlubek; Simone Spaderna; Otto Schmalhofer; Elke Hiendlmeyer; Andreas Jung; Thomas Kirchner
Invasion and metastasis in colorectal cancer: epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and beta-catenin.
Cells, tissues, organs 2005;179(1-2):56-65.
2004: Thomas Brabletz; Simone Spaderna; Jochen Kolb; Falk Hlubek; Gerhard Faller; Christiane J Bruns; Andreas Jung; Jens Nentwich; Isabelle Duluc; Claire Domon-Dell; Thomas Kirchner; Jean-Noel Freund
Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression.
Cancer research 2004;64(19):6973-7.
2004: Gerhard Faller; Arno Dimmler; Tilman Rau; Simone Spaderna; Falk Hlubek; Andreas Jung; Thomas Kirchner; Thomas Brabletz
Evidence for acid-induced loss of Cdx2 expression in duodenal gastric metaplasia.
The Journal of pathology 2004;203(4):904-8.
2004: Richard Strauss; Daniel Neureiter; Bert Westenburger; Markus Wehler; Thomas Kirchner; Eckhart Hahn
Multifactorial risk analysis of bone marrow histiocytic hyperplasia with hemophagocytosis in critically ill medical patients--a postmortem clinicopathologic analysis.
Critical care medicine 2004;32(6):1316-21.
2004: Elke Hiendlmeyer; Susanne Regus; Stella Wassermann; Falk Hlubek; Angela Haynl; Arno Dimmler; Claudia Koch; Claudia Knoll; Moniek van Beest; Ute Reuning; Thomas Brabletz; Thomas Kirchner; Andreas Jung
Beta-catenin up-regulates the expression of the urokinase plasminogen activator in human colorectal tumors.
Cancer research 2004;64(4):1209-14.
2004: Wolfgang M Brueckl; Elvira Heinze; Catrin Milsmann; Axel Wein; Corinna Koebnick; Andreas Jung; Roland S Croner; Thomas Brabletz; Klaus Günther; Thomas Kirchner; Eckhart Hahn; Werner Hohenberger; Heinz Becker; Bertram Reingruber
Prognostic significance of microsatellite instability in curatively resected adenocarcinoma of the small intestine.
Cancer letters 2004;203(2):181-90.
2004: Falk Hlubek; Simone Spaderna; Andreas Jung; Thomas Kirchner; Thomas Brabletz
Beta-catenin activates a coordinated expression of the proinvasive factors laminin-5 gamma2 chain and MT1-MMP in colorectal carcinomas.
International journal of cancer. Journal international du cancer 2004;108(2):321-6.
2004: Maike Buettner; Arno Dimmler; Achim Magener; Thomas Brabletz; Manfred Stolte; Thomas Kirchner; Gerhard Faller
Gastric PDX-1 expression in pancreatic metaplasia and endocrine cell hyperplasia in atrophic corpus gastritis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(1):56-61.
2003: Arno Dimmler; Thomas Brabletz; Falk Hlubek; Manuela Häfner; Tilman Rau; Thomas Kirchner; Gerhard Faller
Transcription of sonic hedgehog, a potential factor for gastric morphogenesis and gastric mucosa maintenance, is up-regulated in acidic conditions.
Laboratory investigation; a journal of technical methods and pathology 2003;83(12):1829-37.
2003: N A C S Wong; Hermann Herbst; K Herrmann; Thomas Kirchner; Andrew S Krajewski; Moganaden Moorghen; F Niedobitek; N Rooney; N A Shepherd; Gerald Niedobitek
Epstein-Barr virus infection in colorectal neoplasms associated with inflammatory bowel disease: detection of the virus in lymphomas but not in adenocarcinomas.
The Journal of pathology 2003;201(2):312-8.
2003: Arno Dimmler; G Seitz; W Hohenberger; Thomas Kirchner; Gerhard Faller
Late pulmonary metastasis in uterine PEComa.
Journal of clinical pathology 2003;56(8):627-8.
2003: Dieter Schwab; Susanna Müller; Thomas Aigner; Daniel Neureiter; Thomas Kirchner; Eckhart Hahn; Martin Raithel
Functional and morphologic characterization of eosinophils in the lower intestinal mucosa of patients with food allergy.
The American journal of gastroenterology 2003;98(7):1525-34.
2003: Daniel Neureiter; Peter U Heuschmann; Sebastian Stintzing; Peter L Kolominsky-Rabas; Letterio Barbera; Andreas Jung; Matthias Ocker; Matthias Maass; Gerhard Faller; Thomas Kirchner
Detection of Chlamydia pneumoniae but not of Helicobacter pylori in symptomatic atherosclerotic carotids associated with enhanced serum antibodies, inflammation and apoptosis rate.
Atherosclerosis 2003;168(1):153-62.
2003: Wolfgang M Brueckl; C Moesch; Thomas Brabletz; Corinna Koebnick; C Riedel; Andreas Jung; Susanne Merkel; Stefan Schaber; Frank Boxberger; Thomas Kirchner; Werner Hohenberger; Eckhart Hahn; Axel Wein
Relationship between microsatellite instability, response and survival in palliative patients with colorectal cancer undergoing first-line chemotherapy.
Anticancer research 2003;23(2C):1773-7.
2003: Thomas Brabletz; Thomas Kirchner
[Morphogenetic aspects of colorectal cancer].
Der Pathologe 2003;24(1):44-8.
2003: Susanna Müller; D Schwab; Thomas Aigner; Thomas Kirchner
[Allergy-associated colitis. Characterization of an entity and its differential diagnoses].
Der Pathologe 2003;24(1):28-35.
2003: Gerhard Faller; R Berndt; F Borchard; Christian Ell; K-H Fuchs; Helene Geddert; Liebwin Gossner; T Günther; Thomas Kirchner; H K Koch; C Langner; J Lüttges; A May; Susanna Müller; G Oberhuber; G Seitz; Manfred Stolte; Andrea Tannapfel; M Vieth; A Walch; Josef Rüschoff
[Histopathological diagnosis of Barrett's mucosa and associated neoplasias. Results of a consensus conference of the Working Group for "Gastroenterological Pathology of the German Society for Pathology" on 22 September 2001].
Der Pathologe 2003;24(1):9-14.
2002: Nicole Reiche; Andreas Jung; Thomas Brabletz; Tanja Vater; Thomas Kirchner; Gerhard Faller
Generation and characterization of human monoclonal scFv antibodies against Helicobacter pylori antigens.
Infection and immunity 2002;70(8):4158-64.
2002: Thomas Brabletz; Andreas Jung; Thomas Kirchner
Beta-catenin and the morphogenesis of colorectal cancer.
Virchows Archiv : an international journal of pathology 2002;441(1):1-11.
2002: Stephan Söder; L Hambach; R Lissner; Thomas Kirchner; Thomas Aigner
Ultrastructural localization of type VI collagen in normal adult and osteoarthritic human articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(6):464-70.
2002: Stefan Ruckert; Elke Hiendlmeyer; Wolfgang M Brueckl; Ursula Oswald; Kurt Beyser; Wolfgang Dietmaier; Angela Haynl; Claudia Koch; Josef Rüschoff; Thomas Brabletz; Thomas Kirchner; Andreas Jung
T-cell factor-4 frameshift mutations occur frequently in human microsatellite instability-high colorectal carcinomas but do not contribute to carcinogenesis.
Cancer research 2002;62(11):3009-13.
2002: Thomas Aigner; Susanna Müller; Daniel Neureiter; Duane M Illstrup; Thomas Kirchner; Johannes Björnsson
Prognostic relevance of cell biologic and biochemical features in conventional chondrosarcomas.
Cancer 2002;94(8):2273-81.
2002: Cornelius Schörle; Carrie Y Inwards; KK Unni; Thomas Kirchner; Thomas Aigner
[Characterisation and differentiation of chondroblastomas and chondromyxoidfibromas - presence and expression of collagen types I and II].
Zeitschrift für Orthopädie und ihre Grenzgebiete 2002;140(2):208-13.
2002: Leonard M Holbach; Fernando Colombo; Ursula Schlötzer-Schrehardt; Thomas Kirchner
Solitary fibrous tumor of the orbit presenting 20 years after Hodgkin's disease.
Orbit (Amsterdam, Netherlands) 2002;21(1):49-54.
2002: Andreas Jung; Stefan Ruckert; P Frank; Thomas Brabletz; Thomas Kirchner
7-Deaza-2'-deoxyguanosine allows PCR and sequencing reactions from CpG islands.
Molecular pathology : MP 2002;55(1):55-7.
2002: Irith Baumann; Wasilis Kolowos; Reinhard E Voll; Bernhard Manger; Udo S Gaipl; Winfried Neuhuber; Thomas Kirchner; Joachim R Kalden; Martin Herrmann
Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus.
Arthritis and rheumatism 2002;46(1):191-201.
2002: Gerhard Faller; Klaus-Michael Keller; Dirk Claeys; Stephan Buderus; Doris Kühlwein; Nicole Reiche; Thomas Kirchner
Prevalence and specificity of antigastric autoantibodies in adolescents infected with Helicobacter pylori.
The Journal of pediatrics 2002;140(1):68-74.
2001: Falk Hlubek; Andreas Jung; N Kotzor; Thomas Kirchner; Thomas Brabletz
Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin.
Cancer research 2001;61(22):8089-93.
2001: Andreas Jung; M Schrauder; U Oswald; Claudia Knoll; P Sellberg; Richard Palmqvist; Gerald Niedobitek; Thomas Brabletz; Thomas Kirchner
The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation.
The American journal of pathology 2001;159(5):1613-7.
2001: Thomas Kirchner; S Müller; T Hattori; K Mukaisyo; Thomas Papadopoulos; Thomas Brabletz; Andreas Jung
Metaplasia, intraepithelial neoplasia and early cancer of the stomach are related to dedifferentiated epithelial cells defined by cytokeratin-7 expression in gastritis.
Virchows Archiv : an international journal of pathology 2001;439(4):512-22.
2001: Arno Dimmler; R Gerhards; C Betz; Klaus Günther; Bertram Reingruber; Thomas Horbach; I Baumann; Thomas Kirchner; Werner Hohenberger; Thomas Papadopoulos
Transcription of cytokeratins 8, 18, and 19 in bone marrow and limited expression of cytokeratins 7 and 20 by carcinoma cells: inherent limitations for RT-PCR in the detection of isolated tumor cells.
Laboratory investigation; a journal of technical methods and pathology 2001;81(10):1351-61.
2001: Wolfgang M Brueckl; J M Preuss; Axel Wein; Andreas Jung; Thomas Brabletz; Rafael Pflüger; Gunther H Wiest; C Wolfl; Thomas Kirchner; Eckhart Hahn; Werner Hohenberger; Klaus Günther
Ki-67 expression and residual tumour (R) classification are associated with disease-free survival in desmoid tumour patients.
Anticancer research 2001;21(5):3615-20.
2001: Thomas Brabletz; Andreas Jung; S Reu; M Porzner; Falk Hlubek; L A Kunz-Schughart; R Knuechel; Thomas Kirchner
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10356-61.
2001: Stephan Söder; Carrie Y Inwards; Susanna Müller; Thomas Kirchner; Thomas Aigner
Cell biology and matrix biochemistry of chondromyxoid fibroma.
American journal of clinical pathology 2001;116(2):271-7.
2001: Thomas Aigner; M Hemmel; Daniel Neureiter; Pia Gebhard; Günther Zeiler; Thomas Kirchner; Louise A McKenna
Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritis human articular knee cartilage: a study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee cartilage.
Arthritis and rheumatism 2001;44(6):1304-12.
2001: S Müller; Daniel Neureiter; Manfred Stolte; C Verbeke; Peter U Heuschmann; Thomas Kirchner; Thomas Aigner
Tenascin: a sensitive and specific diagnostic marker of minimal collagenous colitis.
Virchows Archiv : an international journal of pathology 2001;438(5):435-41.
2001: Angelika Gehrsitz; Louise A McKenna; Stephan Söder; Thomas Kirchner; Thomas Aigner
Isolation of RNA from small human articular cartilage specimens allows quantification of mRNA expression levels in local articular cartilage defects.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2001;19(3):478-81.
2001: D Gottschalk; M Fehn; S Patt; Wolfgang Saeger; Thomas Kirchner; Thomas Aigner
Matrix gene expression analysis and cellular phenotyping in chordoma reveals focal differentiation pattern of neoplastic cells mimicking nucleus pulposus development.
The American journal of pathology 2001;158(5):1571-8.
2001: Falk Hlubek; C Löhberg; J Meiler; Andreas Jung; Thomas Kirchner; Thomas Brabletz
Tip60 is a cell-type-specific transcriptional regulator.
Journal of biochemistry 2001;129(4):635-41.
2001: Frank Sommer; Gerhard Faller; Martin Röllinghoff; Thomas Kirchner; Tak W Mak; Michael Lohoff
Lack of gastritis and of an adaptive immune response in interferon regulatory factor-1-deficient mice infected with Helicobacter pylori.
European journal of immunology 2001;31(2):396-402.
2001: Thomas Kirchner
[A new Approbation Order for teaching medical pathology].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2001;85():60-4.
2001: Gerhard Faller; Thomas Kirchner
[Helicobacter pylori and antigastric autoimmunity].
Der Pathologe 2001;22(1):25-30.
2000: Wolfgang M Brueckl; T Limmert; Thomas Brabletz; Klaus Guenther; Andreas Jung; Kathrin Hermann; Gunther H Wiest; Thomas Kirchner; Werner Hohenberger; Eckhart Hahn; Axel Wein
Mismatch repair deficiency in sporadic synchronous colorectal cancer.
Anticancer research 2000;20(6C):4727-32.
2000: Louise A McKenna; Angelika Gehrsitz; Stephan Söder; Wolfgang Eger; Thomas Kirchner; Thomas Aigner
Effective isolation of high-quality total RNA from human adult articular cartilage.
Analytical biochemistry 2000;286(1):80-5.
2000: Thomas Kirchner; Thomas Brabletz
Patterning and nuclear beta-catenin expression in the colonic adenoma-carcinoma sequence. Analogies with embryonic gastrulation.
The American journal of pathology 2000;157(4):1113-21.
2000: Gerhard Faller; S Ruff; Nicole Reiche; Juergen Hochberger; Eckhart Hahn; Thomas Kirchner
Mucosal production of antigastric autoantibodies in Helicobacter pylori gastritis.
Helicobacter 2000;5(3):129-34.
2000: Gerald Niedobitek; I Baumann; Thomas Brabletz; Renate Lisner; C Winkelmann; G Helm; Thomas Kirchner
Hodgkin's disease and peripheral T-cell lymphoma: composite lymphoma with evidence of Epstein-Barr virus infection.
The Journal of pathology 2000;191(4):394-9.
2000: Karlheinz Trebesius; Klaus Panthel; S Strobel; K Vogt; Gerhard Faller; Thomas Kirchner; M Kist; Jürgen Heesemann; Rainer Haas
Rapid and specific detection of Helicobacter pylori macrolide resistance in gastric tissue by fluorescent in situ hybridisation.
Gut 2000;46(5):608-14.
2000: Thomas Aigner; S Loos; Susanna Müller; L J Sandell; KK Unni; Thomas Kirchner
Cell differentiation and matrix gene expression in mesenchymal chondrosarcomas.
The American journal of pathology 2000;156(4):1327-35.
2000: Gerhard Faller; Thomas Kirchner
Role of antigastric autoantibodies in chronic Helicobacter pylori infection.
Microscopy research and technique 2000;48(6):321-6.
2000: Thomas Brabletz; K Herrmann; Andreas Jung; G Faller; Thomas Kirchner
Expression of nuclear beta-catenin and c-myc is correlated with tumor size but not with proliferative activity of colorectal adenomas.
The American journal of pathology 2000;156(3):865-70.
2000: Stephan Oehler; HG Fassbender; Daniel Neureiter; Carola Meyer-Scholten; Thomas Kirchner; Thomas Aigner
Cell populations involved in pigmented villonodular synovitis of the knee.
The Journal of rheumatology 2000;27(2):463-70.
2000: Thomas Kirchner; Thomas Brabletz
Tumor patterning: analogies of neoplastic morphogenesis with embryogenesis.
Verhandlungen der Deutschen Gesellschaft für Pathologie 2000;84():22-7.
2000: Thomas Brabletz; Andreas Jung; S Dag; S Reu; Thomas Kirchner
[beta-Catenin induces invasive growth by activating matrix metalloproteinases in colorectal carcinoma].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2000;84():175-81.
2000: Gerald Niedobitek; Renate Lisner; Bernd Swoboda; N Rooney; HG Fassbender; Thomas Kirchner; Thomas Aigner; Hermann Herbst
Lack of evidence for an involvement of Epstein-Barr virus infection of synovial membranes in the pathogenesis of rheumatoid arthritis.
Arthritis and rheumatism 2000;43(1):151-4.
1999: Johann Fleischmann; Elisabeth Kremmer; S Müller; Peter Sommer; Thomas Kirchner; Gerald Niedobitek; Friedrich A Grässer
Expression of deoxyuridine triphosphatase (dUTPase) in colorectal tumours.
International journal of cancer. Journal international du cancer 1999;84(6):614-7.
1999: Thomas Aigner; S Loos; Carrie Y Inwards; Roberto Perris; Daniela Perissinotto; KK Unni; Thomas Kirchner
Chondroblastoma is an osteoid-forming, but not cartilage-forming neoplasm.
The Journal of pathology 1999;189(4):463-9.
1999: Johannes Benninger; H Thomas Schneider; Detlef Schuppan; Thomas Kirchner; Eckhart Hahn
Acute hepatitis induced by greater celandine (Chelidonium majus).
Gastroenterology 1999;117(5):1234-7.
1999: Daniel Neureiter; J Böhmer; Thomas Kirchner; Thomas Aigner
Pleomorphic adenomas of the parotid express different mesenchymal phenotypes: demonstration of matrix gene expression products characteristic of the fibroblastic and chondrocytic cell lineages.
Histopathology 1999;35(4):373-9.
1999: Thomas Brabletz; Andreas Jung; S Dag; Falk Hlubek; Thomas Kirchner
beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer.
The American journal of pathology 1999;155(4):1033-8.
1999: Thomas Brabletz; Andreas Jung; Falk Hlubek; C Löhberg; J Meiler; U Suchy; Thomas Kirchner
Negative regulation of CD4 expression in T cells by the transcriptional repressor ZEB.
International immunology 1999;11(10):1701-8.
1999: Peter C Konturek; Piotr Pierzchalski; Stanislaw J Konturek; Holger Meixner; Gerhard Faller; Thomas Kirchner; Eckhart Hahn
Helicobacter pylori induces apoptosis in gastric mucosa through an upregulation of Bax expression in humans.
Scandinavian journal of gastroenterology 1999;34(4):375-83.
1999: Thomas Kirchner; Gerhard Faller
[Helicobacter pylori infections and autoimmunity: the interplay in the pathogenesis of gastritis].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1999;83():56-61.
1999: Gerhard Faller; M Winter; H Steininger; N Lehn; Alexander Meining; E Bayerdörffer; Thomas Kirchner
Decrease of antigastric autoantibodies in Helicobacter pylori gastritis after cure of infection.
Pathology, research and practice 1999;195(4):243-6.
1998: Frank Sommer; Gerhard Faller; Peter C Konturek; Thomas Kirchner; Eckhart Hahn; J Zeus; Martin Röllinghoff; Michael Lohoff
Antrum- and corpus mucosa-infiltrating CD4(+) lymphocytes in Helicobacter pylori gastritis display a Th1 phenotype.
Infection and immunity 1998;66(11):5543-6.
1998: Thomas Aigner; Daniel Neureiter; U Völker; J Belke; Thomas Kirchner
Epithelial-mesenchymal transdifferentiation and extracellular matrix gene expression in pleomorphic adenomas of the parotid salivary gland.
The Journal of pathology 1998;186(2):178-85.
1998: Klaus Günther; Thomas Brabletz; Cornelia Kraus; Otto Dworak; Marc A Reymond; A Jung; Werner Hohenberger; Thomas Kirchner; Ferdinand Köckerling; Wolfgang G Ballhausen
Predictive value of nuclear beta-catenin expression for the occurrence of distant metastases in rectal cancer.
Diseases of the colon and rectum 1998;41(10):1256-61.
1998: Dirk Claeys; Gerhard Faller; Ben J Appelmelk; R Negrini; Thomas Kirchner
The gastric H+,K+-ATPase is a major autoantigen in chronic Helicobacter pylori gastritis with body mucosa atrophy.
Gastroenterology 1998;115(2):340-7.
1998: Thomas Aigner; S Dertinger; Daniel Neureiter; Thomas Kirchner
De-differentiated chondrosarcoma is not a 'de-differentiated' chondrosarcoma.
Histopathology 1998;33(1):11-9.
1998: H Steininger; Gerhard Faller; E Dewald; Thomas Brabletz; Andreas Jung; Thomas Kirchner
Apoptosis in chronic gastritis and its correlation with antigastric autoantibodies.
Virchows Archiv : an international journal of pathology 1998;433(1):13-8.
1998: Ben J Appelmelk; Gerhard Faller; Dirk Claeys; Thomas Kirchner; Christina M.J.E, Vandenbroucke-Grauls
Bugs on trial: the case of Helicobacter pylori and autoimmunity.
Immunology today 1998;19(7):296-9.
1998: Marc A Reymond; Otto Dworak; S Remke; Werner Hohenberger; Thomas Kirchner; Ferdinand Köckerling
DCC protein as a predictor of distant metastases after curative surgery for rectal cancer.
Diseases of the colon and rectum 1998;41(6):755-60.
1998: L Hambach; Daniel Neureiter; Günther Zeiler; Thomas Kirchner; Thomas Aigner
Severe disturbance of the distribution and expression of type VI collagen chains in osteoarthritic articular cartilage.
Arthritis and rheumatism 1998;41(6):986-96.
1998: A Bornemann; Thomas Kirchner
Thymic myoid cell turnover in myasthenia gravis patients and in normal controls.
Virchows Archiv : an international journal of pathology 1998;432(4):357-61.
1998: Gerhard Faller; H Steininger; B Appelmelk; Thomas Kirchner
Evidence of novel pathogenic pathways for the formation of antigastric autoantibodies in Helicobacter pylori gastritis.
Journal of clinical pathology 1998;51(3):244-5.
1998: Gerhard Faller; M Winter; H Steininger; Peter C Konturek; Stanislaw J Konturek; Thomas Kirchner
Antigastric autoantibodies and gastric secretory function in Helicobacter pylori-infected patients with duodenal ulcer and non-ulcer dyspepsia.
Scandinavian journal of gastroenterology 1998;33(3):276-82.
1998: Thomas Aigner; S Oehler; H G Niedobitek; G Fassbender; Thomas Kirchner
[Iron deposits, cell populations and proliferative activity in pigmented villonodular synovitis of the knee joint].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1998;82():327-31.
1998: Thomas Aigner; C C Unni; J Bjornsson; Thomas Kirchner
[Matrix gene expression pattern as indicators of the biology of cartilage-forming tumors].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1998;82():178-83.
1998: Thomas Brabletz; Andreas Jung; Kathrin Hermann; K Günther; Werner Hohenberger; Thomas Kirchner
Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front.
Pathology, research and practice 1998;194(10):701-4.
1997: Gerhard Faller; H Steininger; J Kränzlein; H Maul; T Kerkau; Johannes Hensen; Eckhart Hahn; Thomas Kirchner
Antigastric autoantibodies in Helicobacter pylori infection: implications of histological and clinical parameters of gastritis.
Gut 1997;41(5):619-23.
1997: Thomas Aigner; Daniel Neureiter; S Müller; G Küspert; J Belke; Thomas Kirchner
Extracellular matrix composition and gene expression in collagenous colitis.
Gastroenterology 1997;113(1):136-43.
1997: Thomas Aigner; S Dertinger; SI Vornehm; Jayesh Dudhia; Klaus von der Mark; Thomas Kirchner
Phenotypic diversity of neoplastic chondrocytes and extracellular matrix gene expression in cartilaginous neoplasms.
The American journal of pathology 1997;150(6):2133-41.
1997: H Steininger; R Behrens; Gerhard Faller; C Schindler; Thomas Kirchner
Congenital microvillous atrophy: report of two cases.
General & diagnostic pathology 1997;142(3-4):217-20.
1997: Antje Bornemann; Thomas Aigner; Thomas Kirchner
Spatial and temporal development of the gliovascular tissue in type II lissencephaly.
Acta neuropathologica 1997;93(2):173-7.
1997: Thomas Kirchner; H Steininger; Gerhard Faller
Immunopathology of Helicobacter pylori gastritis.
Digestion 1997;58 Suppl 1():14-6.
1996: Thomas Aigner; S Dertinger; J Belke; Thomas Kirchner
Chondrocytic cell differentiation in clear cell chondrosarcoma.
Human pathology 1996;27(12):1301-5.
1996: Axel Greiner; Thomas Kirchner; German Ott; Alexander Marx; Wolfgang Fischbach; Hans Konrad Müller-Hermelink
Occurrence of multiple lymphoepithelioma-like carcinomas and MALT-type lymphoma in the stomach: detection of EBV in carcinomas but not in lymphoma.
Histopathology 1996;29(1):51-6.
1996: Alexander Marx; A Wilisch; A Schultz; Axel Greiner; Barbara Magi; Vitaliano Pallini; Berthold Schalke; Klaus V Toyka; Wilfred Nix; Thomas Kirchner; Hans Konrad Müller-Hermelink
Expression of neurofilaments and of a titin epitope in thymic epithelial tumors. Implications for the pathogenesis of myasthenia gravis.
The American journal of pathology 1996;148(6):1839-50.
1996: Antje Bornemann; Thomas Kirchner
An immuno-electron-microscopic study of human thymic B cells.
Cell and tissue research 1996;284(3):481-7.
1996: Antje Bornemann; R Pfeiffer; Ernst Beinder; H Wenkel; U Schlicker; R Meyermann; Thomas Kirchner
Three siblings with Walker-Warburg Syndrome.
General & diagnostic pathology 1996;141(5-6):371-5.
1996: Gerhard Faller; H Steininger; M Eck; J Hensen; E G Hann; Thomas Kirchner
Antigastric autoantibodies in Helicobacter pylori gastritis: prevalence, in-situ binding sites and clues for clinical relevance.
Virchows Archiv : an international journal of pathology 1996;427(5):483-6.
1996: A Bornemann; Thomas Kirchner
[Immunoelectron microscopic characterization of myoid cells using anti-desmin and anti-vimentin in normal thymus and thymitis in myasthenia gravis].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1996;80():322.
1996: Thomas Aigner; S I Vornehm; J Belke; Klaus von der Mark; Thomas Kirchner
[Inflammatory cytokine mediated anti-anabolic effects: a potential mechanism in rheumatoid cartilage degeneration].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1996;80():282-7.
1996: A Wilisch; A Schultz; Axel Greiner; Thomas Kirchner; Hans Konrad Müller-Hermelink; Alexander Marx
[Molecular mimicry between neurofilaments and titin as the basis for autoimmunity towards skeletal muscle in paraneoplastic myasthenia gravis].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1996;80():261-6.
1996: H Steininger; Gerhard Faller; E Dewald; Thomas Kirchner
[Apoptosis in chronic gastritis: correlation of glandular apoptosis with antigastric autoantibodies].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1996;80():185-90.
1996: Gerhard Faller; H Steininger; J Kränzlein; H Maul; Thomas Kirchner
[Relevance of antigastric autoantibodies in Helicobacter pylori gastritis].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1996;80():181-4.
1995: H Steininger; U von Streitberg; I Wunder; Gerhard Faller; Thomas Kirchner
Inflammatory, preneoplastic, and neoplastic changes of the gastric mucosa. Examinations by the AgNORT-technique.
General & diagnostic pathology 1995;141(1):15-9.
1995: Jürgen C Becker; Thomas Brabletz; Thomas Kirchner; C T Conrad; Eva-B Bröcker; Ralph A Reisfeld
Negative transcriptional regulation in anergic T cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):2375-8.
1994: German Ott; Thomas Kirchner; Hans Konrad Müller-Hermelink
Monoclonal Epstein-Barr virus genomes but lack of EBV-related protein expression in different types of gastric carcinoma.
Histopathology 1994;25(4):323-9.
1994: Gerhard Faller; J Hensen; P Thierauf; Thomas Kirchner
[Thyrotropin-producing hypophyseal adenoma in a case with congenital thyroid gland hypoplasia].
Der Pathologe 1994;15(4):242-5.
1994: Stefan Ulrich Christl; Wolfgang Scheppach; U Peters; Thomas Kirchner
Cerebral air embolism after gastroduodenoscopy: complication of a duodenocaval fistula.
Gastrointestinal endoscopy 1994;40(3):376-8.
1994: Alexander Marx; D Schömig; A Schultz; Stefan Gattenlöhner; A Jung; Thomas Kirchner; Arthur Melms; Hans Konrad Müller-Hermelink
Distribution of molecules mediating thymocyte-stroma-interactions in human thymus, thymitis and thymic epithelial tumors.
Thymus 1994;23(2):83-93.
1994: Stefan Gattenlöhner; Thomas Brabletz; A Schultz; Alexander Marx; Hans Konrad Müller-Hermelink; Thomas Kirchner
Cloning of a cDNA coding for the acetylcholine receptor alpha-subunit from a thymoma associated with myasthenia [correction of myastenia] gravis.
Thymus 1994;23(2):103-13.
1994: Alexander Marx; D Schömig; A Schultz; A Jung; Stefan Gattenlöhner; Thomas Brabletz; Thomas Kirchner; Hans Konrad Müller-Hermelink
[Thymus-like expression and molecules accessory to division and of thymocyte-stroma interactions in thymomas: a prerequisite for the establishment of an abnormal T-cell repertoire?].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():270-6.
1993: W Fischbach; Z Zidianakis; G Lüke; Thomas Kirchner; Joachim Mössner
DNA mapping of colorectal neoplasms: a flow cytometric study of DNA abnormalities and proliferation.
Gastroenterology 1993;105(4):1126-33.
1993: Alexander Marx; Thomas Kirchner; Axel Greiner; Berthold Schalke; Hans Konrad Müller-Hermelink
Myasthenia gravis-associated thymic epithelial tumors express neurofilaments and are associated with antiaxonal autoimmunity.
Annals of the New York Academy of Sciences 1993;681():107-9.
1993: Hans Konrad Müller-Hermelink; Alexander Marx; K Geuder; Thomas Kirchner
The pathological basis of thymoma-associated myasthenia gravis.
Annals of the New York Academy of Sciences 1993;681():56-65.
1993: G Ott; Thomas Kirchner; S Seidl; Hans Konrad Müller-Hermelink
Primary gastric lymphoma is rarely associated with Epstein-Barr virus.
Virchows Archiv. B, Cell pathology including molecular pathology 1993;64(5):287-91.
1993: Alexander Marx; J Perez; Axel Greiner; A Schulz; Thomas Kirchner; Hans Konrad Müller-Hermelink
[Pathogenesis of autoimmunity in thymoma].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1993;77():282-6.
1992: W Kimura; F Meyer; D Hess; Thomas Kirchner; W Fischbach; Joachim Mössner
Comparison of different treatment modalities in experimental pancreatitis in rats.
Gastroenterology 1992;103(6):1916-24.
1992: Wolfgang Scheppach; H Sommer; Thomas Kirchner; G M Paganelli; P Bartram; Stefan Ulrich Christl; F Richter; Gerda Dusel; H Kasper
Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis.
Gastroenterology 1992;103(1):51-6.
1992: K I Geuder; Alexander Marx; V Witzemann; Berthold Schalke; Thomas Kirchner; Hans Konrad Müller-Hermelink
Genomic organization and lack of transcription of the nicotinic acetylcholine receptor subunit genes in myasthenia gravis-associated thymoma.
Laboratory investigation; a journal of technical methods and pathology 1992;66(4):452-8.
1992: Alexander Marx; Thomas Kirchner; Axel Greiner; Hans Konrad Müller-Hermelink; Berthold Schalke; M Osborn
Neurofilament epitopes in thymoma and antiaxonal autoantibodies in myasthenia gravis.
Lancet 1992;339(8795):707-8.
1992: W Paulus; Thomas Kirchner; M Michaela; Joachim Kühl; Monika Warmuth-Metz; Niels Sörensen; Hans Konrad Müller-Hermelink; Wolfgang Roggendorf
Histiocytic tumor of Meckel's cave. An intracranial equivalent of juvenile xanthogranuloma of the skin.
The American journal of surgical pathology 1992;16(1):76-83.
1992: K I Geuder; Alexander Marx; V Witzemann; Berthold Schalke; Klaus V Toyka; Thomas Kirchner; Hans Konrad Müller-Hermelink
Pathogenetic significance of fetal-type acetylcholine receptors on thymic myoid cells in myasthenia gravis.
Developmental immunology 1992;2(2):69-75.
1992: W Paulus; Wolfgang Roggendorf; Thomas Kirchner
Ki-M1P as a marker for microglia and brain macrophages in routinely processed human tissues.
Acta neuropathologica 1992;84(5):538-44.
1992: Alexander Marx; M Osborn; S Tzartos; K I Geuder; Berthold Schalke; Wilfred Nix; Thomas Kirchner; Hans Konrad Müller-Hermelink
A striational muscle antigen and myasthenia gravis-associated thymomas share an acetylcholine-receptor epitope.
Developmental immunology 1992;2(2):77-84.
1992: Alexander Marx; Thomas Kirchner; Axel Greiner; Berthold Schalke; Hans Konrad Müller-Hermelink
[Neurofilament expression in thymic epithelial tumors and anti-axonal autoantibodies in myasthenia gravis: a model for autoimmunity by abnormal T cell selection].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1992;76():256-61.
1991: B Borisch; K Ellinger; Frank Neipel; Bernhard Fleckenstein; Thomas Kirchner; M Michaela Ott; Hans Konrad Müller-Hermelink
Lymphadenitis and lymphoproliferative lesions associated with the human herpes virus-6 (HHV-6).
Virchows Archiv. B, Cell pathology including molecular pathology 1991;61(3):179-87.
1990: M M Hey; Alfred C Feller; Thomas Kirchner; J Müller; Hans Konrad Müller-Hermelink
Genomic analysis of T-cell receptor and immunoglobulin antigen receptor genes and breakpoint cluster regions in gastrointestinal lymphomas.
Human pathology 1990;21(12):1283-7.
1990: Thomas Papadopoulos; Thomas Kirchner; M Bergmann; Hans Konrad Müller-Hermelink
Primary liposarcoma of the jejunum.
Pathology, research and practice 1990;186(6):803-6; discussion 807-8.
1990: Justus G Müller; Thomas Kirchner; J Pannenbecker; Hans Konrad Müller-Hermelink
[Hepatic capillariasis. Morphology and differential diagnosis].
Der Pathologe 1990;11(5):300-3.
1990: Alexander Marx; R O'Connor; K I Geuder; Florian Hoppe; Berthold Schalke; S Tzartos; I Kalies; Thomas Kirchner; Hans Konrad Müller-Hermelink
Characterization of a protein with an acetylcholine receptor epitope from myasthenia gravis-associated thymomas.
Laboratory investigation; a journal of technical methods and pathology 1990;62(3):279-86.
1990: B Borisch; Thomas Kirchner; Alexander Marx; Hans Konrad Müller-Hermelink
Absence of the Epstein-Barr virus genome in the normal thymus, thymic epithelial tumors, thymic lymphoid hyperplasia in a European population.
Virchows Archiv. B, Cell pathology including molecular pathology 1990;59(6):359-65.
1990: Thomas Kirchner; K I Geuder; Alexander Marx; Hans Konrad Müller-Hermelink
[Nicotinic acetylcholine receptors in tumors with rhabdomyomatous differentiation. Immunohistochemical amd molecular genetic demonstration].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1990;74():409-14.
1990: Alexander Marx; K I Geuder; M Altmannsberger; Edgar Schömig; Thomas Kirchner; Hans Konrad Müller-Hermelink
[Significance of neuronal acetylcholine receptors as differentiation antigens in neuroblastomas and paragangliomas].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1990;74():354-8.
1989: Alexander Marx; Thomas Kirchner; Florian Hoppe; R O'Connor; Berthold Schalke; S Tzartos; Hans Konrad Müller-Hermelink
Proteins with epitopes of the acetylcholine receptor in epithelial cell cultures of thymomas in myasthenia gravis.
The American journal of pathology 1989;134(4):865-77.
1989: Thomas Kirchner; Berthold Schalke; Alexander Marx; Hans Konrad Müller-Hermelink
Evaluation of prognostic features in thymic epithelial tumors.
Thymus 1989;14(1-3):195-203.
1989: K I Geuder; R Schoepfer; Thomas Kirchner; Alexander Marx; Hans Konrad Müller-Hermelink
The gene of the alpha-subunit of the acetylcholine receptor: molecular organisation and transcription in myasthenia-associated thymomas.
Thymus 1989;14(1-3):179-86.
1989: Alexander Marx; R O'Connor; S Tzartos; I Kalies; Thomas Kirchner; Hans Konrad Müller-Hermelink
Acetylcholine receptor epitope in proteins of myasthenia gravis-associated thymomas and non-thymic tissues.
Thymus 1989;14(1-3):171-8.
1989: Thomas Papadopoulos; Thomas Kirchner; Alexander Marx; Hans Konrad Müller-Hermelink
Primary cultures of human thymic epithelial tumors. Morphological and immunocytochemical characterization.
Virchows Archiv. B, Cell pathology including molecular pathology 1989;56(6):363-70.
1988: M Schwermann; W Lechner; C Elsner; Thomas Kirchner
[Pemphigus vulgaris with involvement of duodenum and colon].
Zeitschrift für Hautkrankheiten 1988;63(2):101-4.
1988: Thomas Kirchner; S Tzartos; Florian Hoppe; Berthold Schalke; H Wekerle; Hans Konrad Müller-Hermelink
Pathogenesis of myasthenia gravis. Acetylcholine receptor-related antigenic determinants in tumor-free thymuses and thymic epithelial tumors.
The American journal of pathology 1988;130(2):268-80.
1988: Thomas Kirchner; Florian Hoppe; Alexander Marx; Thomas Papadopoulos; Hans Konrad Müller-Hermelink
[Histogenic and functional markers of epithelial differentiation in thymomas and thymus carcinomas].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1988;72():349-53.
1988: Thomas Kirchner; Florian Hoppe; Berthold Schalke; Hans Konrad Müller-Hermelink
Microenvironment of thymic myoid cells in myasthenia gravis.
Virchows Archiv. B, Cell pathology including molecular pathology 1988;54(5):295-302.
1988: Thomas Kirchner; S Tzartos; Florian Hoppe; Berthold Schalke; H Wekerle; Hans Konrad Müller-Hermelink
Monoclonal antibodies as probes for acetylcholine receptor epitopes in thymuses and thymic epithelial tumors of patients with myasthenia gravis and nonmyasthenic controls.
Annals of the New York Academy of Sciences 1988;540():508-10.
1988: Hans Konrad Müller-Hermelink; Thomas Kirchner; Florian Hoppe; S Demel
Thymic myoid cells--stimulants and/or targets of autoimmune myasthenia gravis.
Monographs in allergy 1988;25():68-74.
1987: Thomas Kirchner; Florian Hoppe; Hans Konrad Müller-Hermelink; Berthold Schalke; S Tzartos
Acetylcholine receptor epitopes on epithelial cells of thymoma in myasthenia gravis.
Lancet 1987;1(8526):218.