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George Kirov

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TOP 3
Hywel J Williams; George Kirov; Stephen Monks; Kieran C Murphy; Michael C O'Donovan; Michael J Owen
Schizophrenia two-hit hypothesis in velo-cardio facial syndrome.
Elitza T Betcheva; Ivanka I Dimova; Savina P Hadjidekova; Naoyuki Kamatani; Sena K Karachanak; George Kirov; Michiaki Kubo; vihra milanova; Taisei Mushiroda; Drozdstoy S Stoyanov; Atsushi Takahashi; Todor Tolev; Draga Toncheva; Radoslava V Vazharova; Adelina G Yosifova; Irina T Zaharieva; Yusuke Nakamura
Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
Kathryn J Peall; Michael Samuel; Daniel J Smith; Martin Smith; Adrian J Waite; Mark Wardle; Thomas T Warner; Cathy White; Alan Whone; Narinder Bajaj; Derek J Blake; Patrick F Chinnery; Tammy Hedderly; Philip Jardine; Mary D King; George Kirov; Manju A Kurian; Jean-Pierre Lin; Andrew Lux; Bryan Lynch; Timothy Lynch; Sean O'Riordan; Michael J Owen; Hardev Pall; Huw R Morris
SGCE mutations cause psychiatric disorders: clinical and genetic characterization.

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All Publications

2013: Hywel J Williams; George Kirov; Stephen Monks; Kieran C Murphy; Michael C O'Donovan; Michael J Owen
Schizophrenia two-hit hypothesis in velo-cardio facial syndrome.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2013;162B(2):177-82.
2013: Elitza T Betcheva; Ivanka I Dimova; Savina P Hadjidekova; Naoyuki Kamatani; Sena K Karachanak; George Kirov; Michiaki Kubo; vihra milanova; Taisei Mushiroda; Drozdstoy S Stoyanov; Atsushi Takahashi; Todor Tolev; Draga Toncheva; Radoslava V Vazharova; Adelina G Yosifova; Irina T Zaharieva; Yusuke Nakamura
Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
Psychiatric genetics 2013;23(1):11-9.
2013: Kathryn J Peall; Michael Samuel; Daniel J Smith; Martin Smith; Adrian J Waite; Mark Wardle; Thomas T Warner; Cathy White; Alan Whone; Narinder Bajaj; Derek J Blake; Patrick F Chinnery; Tammy Hedderly; Philip Jardine; Mary D King; George Kirov; Manju A Kurian; Jean-Pierre Lin; Andrew Lux; Bryan Lynch; Timothy Lynch; Sean O'Riordan; Michael J Owen; Hardev Pall; Huw R Morris
SGCE mutations cause psychiatric disorders: clinical and genetic characterization.
Brain : a journal of neurology 2013;136(Pt 1):294-303.
2012: Hywel J Williams; Michael J Owen; Sarah Dwyer; Lyudmila Georgieva; George Kirov; Michael C O'Donovan
Absence of de novo point mutations in exons of GRIN2B in a large schizophrenia trio sample.
Schizophrenia research 2012;141(2-3):274-6.
2012: Detelina Grozeva; Matthew Hurles; George Kirov; Michael C O'Donovan; Michael J Owen; Chris P Barnes; Donald F Conrad; Nick Craddock
Independent estimation of the frequency of rare CNVs in the UK population confirms their role in schizophrenia.
Schizophrenia research 2012;135(1-3):1-7.
2012: George Kirov; Noboru H Komiyama; J Moran; Ivan Nikolov; Michael C O'Donovan; P I Olason; A Bayés; Yvonne Böttcher; K Chambert; Jyoti S Choudhary; Mark Collins; E Fernandez; M Fjodorova; Lyudmila Georgieva; S G N Grant; Detelina Grozeva; Peter Holmans; M Ikeda; Dobril Ivanov; Andrew J Pocklington; S Purcell; E Rees; D Ruderfer; P Sklar; Hreinn Stefansson; K Stefansson; Draga Toncheva; R Wollerton; Louie van de Lagemaat; Michael J Owen
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.
Molecular psychiatry 2012;17(2):142-53.
2012: A L Richards; A R Sanders; P M Visscher; Michael J Owen; S Purcell; Nick Craddock; P V Gejman; Peter Holmans; Lesley Jones; George Kirov; Douglas F Levinson; Valentina Moskvina; Michael C O'Donovan
Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain.
Molecular psychiatry 2012;17(2):193-201.
2011: Elliott Rees; Valentina Moskvina; Michael C O'Donovan; Michael J Owen; George Kirov
De novo rates and selection of schizophrenia-associated copy number variants.
Biological psychiatry 2011;70(12):1109-14.
2011: L S Carroll; George Kirov; Michael C O'Donovan; J Walters; Hywel J Williams; Michael J Owen
Mutation screening of the 3q29 microdeletion syndrome candidate genes DLG1 and PAK2 in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(7):844-9.
2011: A Yosifova; I Zaharieva; Ivanka Dimova; I Gerdjikov; S Hadjidekova; N Kamatani; Y Kamatani; S Karachanak; George Kirov; M Kubo; N Madjirova; vihra milanova; Taisei Mushiroda; Michael C O'Donovan; Michael J Owen; N Poryazova; D Stoianov; A Takahashi; T Tolev; Draga Toncheva; R Vazharova; Y Nakamura
Genome-wide association study on bipolar disorder in the Bulgarian population.
Genes, brain, and behavior 2011;10(7):789-97.
2011: Rhodri Ll Smith; Hywel Williams; Alex Richards; Sarah Dwyer; George Kirov; Deborah Knight; Michael C O'Donovan; Michael J Owen
Analysis of neurogranin (NRGN) in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(5):532-5.
2011: Elaine K Green; Detelina Grozeva; R Sims; Rachel Raybould; Liz Forty; Katherine Gordon-Smith; E Russell; D St Clair; A H Young; Ian Nicol Ferrier; George Kirov; Ian Jones; Lesley Jones; Michael J Owen; Michael C O'Donovan; Nick Craddock
DISC1 exon 11 rare variants found more commonly in schizoaffective spectrum cases than controls.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(4):490-2.
2011: Marian Hamshere; Peter Holmans; Ian Richard Jones; Lesley Jones; George Kirov; Peter McGuffin; Andrew McQuillin; Valentina Moskvina; Michael C O'Donovan; Michael J Owen; S Purcell; P Sklar; D St Clair; A H Young; Anne Farmer; Ian Nicol Ferrier; Elaine K Green; Detelina Grozeva; H Gurling; N Bass; Nick Craddock
Polygenic dissection of the bipolar phenotype.
The British journal of psychiatry : the journal of mental science 2011;198(4):284-8.
2010: Michael E Talkowski; Kathleen L McCann; Michael Chen; Lora McClain; Mikhil Bamne; Joel Wood; Kodavali V Chowdari; Annie Watson; Konasale M Prasad; George Kirov; Lyudmila Georgieva; Draga Toncheva; Hader A Mansour; David A Lewis; Michael J Owen; Michael O'Donovan; Panagiotis Papasaikas; Patrick Sullivan; Douglas Ruderfer; Jeffrey K Yao; Sherry Leonard; Pramod Thomas; Fabio Miyajima; John Quinn; A Javier Lopez; Vishwajit L Nimgaonkar
Fine-mapping reveals novel alternative splicing of the dopamine transporter.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(8):1434-47.
2010: John Tredget; Anna Kirov; George Kirov
Effects of chronic lithium treatment on renal function.
Journal of affective disorders 2010;126(3):436-40.
2010: L S Carroll; Nigel M Williams; Valentina Moskvina; E Russell; Nadine Norton; Hywel J Williams; Tim Peirce; Lyudmila Georgieva; Sarah Dwyer; Detelina Grozeva; E Greene; Anne Farmer; Peter McGuffin; Derek W Morris; Aiden Corvin; Michael Gill; Dan Rujescu; Pak Sham; Peter Holmans; Ian Jones; George Kirov; Nick Craddock; Michael C O'Donovan; Michael J Owen
Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha.
Molecular psychiatry 2010;15(11):1101-11.
2010: Elaine K Green; Detelina Grozeva; Ian Jones; Lesley Jones; George Kirov; Sian Caesar; Katherine Gordon-Smith; C Fraser; Liz Forty; E Russell; Marian Hamshere; Valentina Moskvina; Ivan Nikolov; Anne Farmer; Peter McGuffin; Peter Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia.
Molecular psychiatry 2010;15(10):1016-22.
2010: Detelina Grozeva; George Kirov; Dobril Ivanov; Ian Richard Jones; Lisa Jones; Elaine K Green; David M St Clair; Allan H Young; Nicol Ferrier; Anne E Farmer; Peter McGuffin; Peter Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock
Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia.
Archives of general psychiatry 2010;67(4):318-27.
2010: Masashi Ikeda; Branko Aleksic; George Kirov; Yoko Kinoshita; Yoshio Yamanouchi; Tsuyoshi Kitajima; Kunihiro Kawashima; Tomo Okochi; Taro Kishi; Irina Zaharieva; Michael J Owen; Michael C O'Donovan; Norio Ozaki; Nakao Iwata
Copy number variation in schizophrenia in the Japanese population.
Biological psychiatry 2010;67(3):283-6.
2010: Nick Craddock; Lesley Jones; I R Jones; George Kirov; Elaine K Green; Detelina Grozeva; Valentina Moskvina; Ivan Nikolov; Marian Hamshere; D Vukcevic; Sian Caesar; Katherine Gordon-Smith; C Fraser; E Russell; Nadine Norton; Gerome Breen; D St Clair; David A Collier; A H Young; Ian Nicol Ferrier; Anne Farmer; Peter McGuffin; Peter Holmans; P Donnelly; Michael J Owen; Michael C O'Donovan
Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.
Molecular psychiatry 2010;15(2):146-53.
2010: George Kirov
The role of copy number variation in schizophrenia.
Expert review of neurotherapeutics 2010;10(1):25-32.
2009: Elaine K Green; Detelina Grozeva; Rachel Raybould; Gareth P Elvidge; Stuart Macgregor; Ian Craig; Anne Farmer; Peter McGuffin; Liz Forty; Lisa Jones; Ian Jones; Michael C O'Donovan; Michael J Owen; George Kirov; Nick Craddock
P2RX7: A bipolar and unipolar disorder candidate susceptibility gene?
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(8):1063-9.
2009: George Kirov; Dan Rujescu; Andres Ingason; David A Collier; Michael C O'Donovan; Michael J Owen
Neurexin 1 (NRXN1) deletions in schizophrenia.
Schizophrenia bulletin 2009;35(5):851-4.
2009: Adelina Yosifova; Taisei Mushiroda; Drozdstoi Stoianov; Radoslava Vazharova; Ivanka Dimova; Sena Karachanak; Irina Zaharieva; vihra milanova; Nadejda Madjirova; Ivan Gerdjikov; Todor Tolev; Stoyanka Velkova; George Kirov; Michael J Owen; Michael C O'Donovan; Draga Toncheva; Yusuke Nakamura
Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
Journal of affective disorders 2009;117(1-2):87-97.
2009: George Kirov; I Zaharieva; Lyudmila Georgieva; Valentina Moskvina; Ivan Nikolov; Sven Cichon; A Hillmer; D Toncheva; Michael J Owen; Michael C O'Donovan
A genome-wide association study in 574 schizophrenia trios using DNA pooling.
Molecular psychiatry 2009;14(8):796-803.
2009: Marian Hamshere; Elaine K Green; I R Jones; Lesley Jones; Valentina Moskvina; George Kirov; Detelina Grozeva; Ivan Nikolov; D Vukcevic; Sian Caesar; Katherine Gordon-Smith; C Fraser; E Russell; Gerome Breen; D St Clair; D A Collier; A H Young; Ian Nicol Ferrier; Anne Farmer; Peter McGuffin; Peter Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock
Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.
The British journal of psychiatry : the journal of mental science 2009;195(1):23-9.
2009: Marian Hamshere; Katherine Gordon-Smith; Liz Forty; Lisa Jones; Sian Caesar; Christine Fraser; Sally Hyde; John Tredget; George Kirov; Ian Jones; Nick Craddock; Daniel J Smith
Age-at-onset in bipolar-I disorder: mixture analysis of 1369 cases identifies three distinct clinical sub-groups.
Journal of affective disorders 2009;116(1-2):23-9.
2009: Michael E Talkowski; Lora McClain; Trina Allen; L Dianne Bradford; Monica Calkins; Neil Edwards; Lyudmila Georgieva; Rodney Go; Ruben Gur; Raquel Gur; George Kirov; Kodavali V Chowdari; Joseph Kwentus; Paul Lyons; Hader A Mansour; Joseph McEvoy; Michael C O'Donovan; Judith O'Jile; Michael J Owen; Alberto B Santos; Robert Savage; Draga Toncheva; Gerard Vockley; Joel Wood; Bernie Devlin; Vishwajit L Nimgaonkar
Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(4):560-9.
2009: George Kirov; Detelina Grozeva; Nadine Norton; Dobril Ivanov; Kiran K Mantripragada; Peter Holmans; Nick Craddock; Michael J Owen; Michael C O'Donovan
Support for the involvement of large copy number variants in the pathogenesis of schizophrenia.
Human molecular genetics 2009;18(8):1497-503.
2008: Michael C O'Donovan; George Kirov; Michael J Owen
Phenotypic variations on the theme of CNVs.
Nature genetics 2008;40(12):1392-3.
2008: Lyudmila Georgieva; Albena Dimitrova; Dobril Ivanov; Ivan Nikolov; Nigel M Williams; Detelina Grozeva; Irina Zaharieva; Draga Toncheva; Michael J Owen; George Kirov; Michael C O'Donovan
Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia.
Biological psychiatry 2008;64(5):419-27.
2008: Michael E Talkowski; George Kirov; Mikhil Bamne; Lyudmila Georgieva; Gonzalo Torres; Hader A Mansour; Kodavali V Chowdari; vihra milanova; Joel Wood; Lora McClain; Konasale Prasad; Brian H Shirts; Jianping Zhang; Michael C O'Donovan; Michael J Owen; Bernie Devlin; Vishwajit L Nimgaonkar
A network of dopaminergic gene variations implicated as risk factors for schizophrenia.
Human molecular genetics 2008;17(5):747-58.
2008: Nigel M Williams; Beate Glaser; Nadine Norton; Hywel Williams; Timothy Pierce; Valentina Moskvina; Stephen Monks; Jurgen Del-Favero; Dirk Goossens; Dan Rujescu; Ina Giegling; George Kirov; Nicholas Craddock; Kieran C Murphy; Michael C O'Donovan; Michael J Owen
Strong evidence that GNB1L is associated with schizophrenia.
Human molecular genetics 2008;17(4):555-66.
2008: George Kirov; Gumus Gumus; Wei Chen; Nadine Norton; Lyudmila Georgieva; Murat Sari; Michael C O'Donovan; Fikret Erdogan; Michael J Owen; Hans-Hilger Ropers; Reinhard Ullmann
Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia.
Human molecular genetics 2008;17(3):458-65.
2008: Richard Abraham; Valentina Moskvina; Rebecca Sims; Paul Hollingworth; Angharad Morgan; Lyudmila Georgieva; Kimberley Dowzell; Sven Cichon; Axel M Hillmer; Michael C O'Donovan; Julie Williams; Michael J Owen; George Kirov
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling.
BMC medical genomics 2008;1():44.
2008: Irina Zaharieva; Lyudmila Georgieva; Ivan Nikolov; George Kirov; Michael J Owen; Michael C O'Donovan; Draga Toncheva
Association study in the 5q31-32 linkage region for schizophrenia using pooled DNA genotyping.
BMC psychiatry 2008;8():11.
2007: Vaughan Bell; Venu Reddy; Peter W Halligan; George Kirov; Hadyn Ellis
Relative suppression of magical thinking: a transcranial magnetic stimulation study.
Cortex; a journal devoted to the study of the nervous system and behavior 2007;43(4):551-7.
2007: David Gunnell; Shon Lewis; J Wilkinson; Lyudmila Georgieva; G Smith Davey; Ian N M Day; Jeff M P Holly; Michael C O'Donovan; Michael J Owen; George Kirov; Stanley Zammit
IGF1, growth pathway polymorphisms and schizophrenia: a pooling study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(1):117-20.
2006: Beate Glaser; Valentina Moskvina; George Kirov; Kieran C Murphy; Hywel Williams; Nigel Williams; Michael J Owen; Michael C O'Donovan
Analysis of ProDH, COMT and ZDHHC8 risk variants does not support individual or interactive effects on schizophrenia susceptibility.
Schizophrenia research 2006;87(1-3):21-7.
2006: Najeeb Khalid; Maria Atkins; George Kirov
The effects of etomidate on seizure duration and electrical stimulus dose in seizure-resistant patients during electroconvulsive therapy.
The journal of ECT 2006;22(3):184-8.
2006: Elaine K Green; Nadine Norton; Tim Peirce; Detelina Grozeva; George Kirov; Michael J Owen; Michael C O'Donovan; Nick Craddock
Evidence that a DISC1 frame-shift deletion associated with psychosis in a single family may not be a pathogenic mutation.
Molecular psychiatry 2006;11(9):798-9.
2006: Lyudmila Georgieva; Valentina Moskvina; Tim Peirce; Nadine Norton; Nicholas J Bray; Lesley Jones; Peter Holmans; Stuart Macgregor; Stanley Zammit; Jennifer Wilkinson; Hywel Williams; Ivan Nikolov; Nigel Williams; Dobril Ivanov; Kenneth L Davis; Vahram Haroutunian; Joseph Buxbaum; Nick Craddock; George Kirov; Michael J Owen; Michael C O'Donovan
Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12469-74.
2006: A Bakhsh; George Kirov; John W Gregory; E D Williams; Marian Ludgate
A new form of familial multi-nodular goitre with progression to differentiated thyroid cancer.
Endocrine-related cancer 2006;13(2):475-83.
2006: Nigel M Williams; Elaine K Green; Stuart Macgregor; Sarah Dwyer; Nadine Norton; Hywel Williams; Rachel Raybould; Detelina Grozeva; Marian Hamshere; Stanley Zammit; Lisa Jones; Alastair G Cardno; George Kirov; Ian Jones; Michael C O'Donovan; Michael J Owen; Nick Craddock
Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder.
Archives of general psychiatry 2006;63(4):366-73.
2006: Nadine Norton; Valentina Moskvina; Derek W Morris; Nicholas J Bray; Stanley Zammit; Nigel M Williams; Hywel J Williams; Anna Preece; Sarah Dwyer; Jennifer C Wilkinson; Gillian Spurlock; George Kirov; Paul R Buckland; John L Waddington; Michael Gill; Aiden Corvin; Michael J Owen; Michael C O'Donovan
Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2006;141B(1):96-101.
2006: George Kirov; Ivan Nikolov; Lyudmila Georgieva; Valentina Moskvina; Michael J Owen; Michael C O'Donovan
Pooled DNA genotyping on Affymetrix SNP genotyping arrays.
BMC genomics 2006;7():27.
2006: Elaine K Green; Rachel Raybould; Stuart Macgregor; Sally Hyde; Allan H Young; Michael C O'Donovan; Michael J Owen; George Kirov; Lisa Jones; Ian Jones; Nick Craddock
Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK.
The British journal of psychiatry : the journal of mental science 2006;188():21-5.
2005: Marian Hamshere; Philip Bennett; Nigel Williams; Ricardo Segurado; Alastair G Cardno; Nadine Norton; David Lambert; Hywel Williams; George Kirov; Aiden Corvin; Peter Holmans; Lisa Jones; Ian Jones; Michael Gill; Michael C O'Donovan; Michael J Owen; Nick Craddock
Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13.
Archives of general psychiatry 2005;62(10):1081-8.
2005: B Glaser; George Kirov; Nicholas J Bray; Elaine Green; Michael C O'Donovan; Nick Craddock; Michael J Owen
Identification of a potential bipolar risk haplotype in the gene encoding the winged-helix transcription factor RFX4.
Molecular psychiatry 2005;10(10):920-7.
2005: Hywel J Williams; Beate Glaser; Nigel M Williams; Nadine Norton; Stanley Zammit; Stuart Macgregor; George Kirov; Michael J Owen; Michael C O'Donovan
No association between schizophrenia and polymorphisms in COMT in two large samples.
The American journal of psychiatry 2005;162(9):1736-8.
2005: David Lambert; Fiona Middle; Marian Hamshere; Ricardo Segurado; Rachel Raybould; Aiden Corvin; Elaine Green; E O'Mahony; Ivan Nikolov; T Mulcahy; S Haque; S Bort; Philip Bennett; Nadine Norton; Michael J Owen; George Kirov; Corinne Lendon; Lesley Jones; Ian Jones; Peter Holmans; Michael Gill; Nick Craddock
Stage 2 of the Wellcome Trust UK-Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16-q21, 4q12-q21, 9p21, 10p14-p12 and 18q22.
Molecular psychiatry 2005;10(9):831-41.
2005: George Kirov; John Tredget; Rhys John; Michael J Owen; John H Lazarus
A cross-sectional and a prospective study of thyroid disorders in lithium-treated patients.
Journal of affective disorders 2005;87(2-3):313-7.
2005: Beate Glaser; Johannes Schumacher; Hywel J Williams; Rami Abou Jamra; Nikolai Ianakiev; Radoi Milev; Stephanie Ohlraun; Thomas G. Schulze; Piotr M Czerski; Joanna Hauser; Erik G Jönsson; Göran C Sedvall; Norman Klopp; Thomas Illig; Tim Becker; Peter Propping; Nigel M Williams; Sven Cichon; George Kirov; Marcella Rietschel; Kieran C Murphy; Michael C O'Donovan; Markus M Nöthen; Michael J Owen
No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples.
Biological psychiatry 2005;58(1):78-80.
2005: Elaine K Green; Rachel Raybould; Stuart Macgregor; Katherine Gordon-Smith; Jessica Heron; Sally Hyde; Detelina Grozeva; Marian Hamshere; Nigel Williams; Michael J Owen; Michael C O'Donovan; Lisa Jones; Ian Jones; George Kirov; Nick Craddock
Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder.
Archives of general psychiatry 2005;62(6):642-8.
2005: George Kirov; Michael C O'Donovan; Michael J Owen
Finding schizophrenia genes.
The Journal of clinical investigation 2005;115(6):1440-8.
2005: John Tredget; George Kirov; Emma Dunn
Transcranial magnetic stimulation for patients with depression.
Nursing standard (Royal College of Nursing (Great Britain) : 1987) 2005;19(37):49-50.
2005: Rachel Raybould; Elaine K Green; Stuart Macgregor; Katherine Gordon-Smith; Jessica Heron; Sally Hyde; Sian Caesar; Ivan Nikolov; Nigel Williams; Lisa Jones; Michael C O'Donovan; Michael J Owen; Ian Jones; George Kirov; Nick Craddock
Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1).
Biological psychiatry 2005;57(7):696-701.
2005: George Kirov; John Tredget; Emma Dunn; Valentina Moskvina; Roger Beer; Najeeb Khalid
Underpowered repetitive transcranial magnetic stimulation might not be an effective antidepressant treatment.
The Journal of clinical psychiatry 2005;66(4):543; author reply 543-4.
2005: Beate Glaser; George Kirov; Elaine Green; Nick Craddock; Michael J Owen
Linkage disequilibrium mapping of bipolar affective disorder at 12q23-q24 provides evidence for association at CUX2 and FLJ32356.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;132B(1):38-45.
2005: George Kirov; John Tredget
Add-on topiramate reduces weight in overweight patients with affective disorders: a clinical case series.
BMC psychiatry 2005;5():19.
2005: Elaine Green; Gareth P Elvidge; Nick Jacobsen; Beate Glaser; Ian Jones; Michael C O'Donovan; George Kirov; Michael J Owen; Nick Craddock
Localization of bipolar susceptibility locus by molecular genetic analysis of the chromosome 12q23-q24 region in two pedigrees with bipolar disorder and Darier's disease.
The American journal of psychiatry 2005;162(1):35-42.
2005: Albena Dimitrova; vihra milanova; S Krastev; Ivan Nikolov; Draga Toncheva; Michael J Owen; George Kirov
Association study of myo-inositol monophosphatase 2 (IMPA2) polymorphisms with bipolar affective disorder and response to lithium treatment.
The pharmacogenomics journal 2005;5(1):35-41.
2004: Jane E Farbrother; George Kirov; Michael J Owen; Ricardo Pong-Wong; Chris S Haley; Jeremy A Guggenheim
Linkage analysis of the genetic loci for high myopia on 18p, 12q, and 17q in 51 U.K. families.
Investigative ophthalmology & visual science 2004;45(9):2879-85.
2004: Jane E Farbrother; George Kirov; Michael J Owen; Jeremy A Guggenheim
Family aggregation of high myopia: estimation of the sibling recurrence risk ratio.
Investigative ophthalmology & visual science 2004;45(9):2873-8.
2004: George Kirov; Dobril Ivanov; Nigel M Williams; Anna Preece; Ivan Nikolov; Radoi Milev; Svetlinka Koleva; Albena Dimitrova; Draga Toncheva; Michael C O'Donovan; Michael J Owen
Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria.
Biological psychiatry 2004;55(10):971-5.
2004: Darko Turic; Kate Langley; George Kirov; Michael J Owen; Anita Thapar; Michael C O'Donovan
Direct analysis of the genes encoding G proteins G alpha T2, G alpha o, G alpha Z in ADHD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;127B(1):68-72.
2004: Nigel M Williams; Anna Preece; Derek W Morris; Gillian Spurlock; Nicholas J Bray; M Stephens; Nadine Norton; Hywel Williams; M Clement; Sarah Dwyer; C Curran; J Wilkinson; Valentina Moskvina; John L Waddington; Michael Gill; Aiden Corvin; Stanley Zammit; George Kirov; Michael J Owen; Michael C O'Donovan
Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).
Archives of general psychiatry 2004;61(4):336-44.
2004: Nigel M Williams; Anna Preece; Gillian Spurlock; Nadine Norton; Hywel J Williams; Robin G McCreadie; Paul R Buckland; Val Sharkey; Kodavali V Chowdari; Stanley Zammit; Vishwajit L Nimgaonkar; George Kirov; Michael J Owen; Michael C O'Donovan
Support for RGS4 as a susceptibility gene for schizophrenia.
Biological psychiatry 2004;55(2):192-5.
2004: Nick Craddock; Ian Jones; George Kirov; Lisa Jones
The Bipolar Affective Disorder Dimension Scale (BADDS)--a dimensional scale for rating lifetime psychopathology in bipolar spectrum disorders.
BMC psychiatry 2004;4():19.
2003: Dobril Ivanov; George Kirov; Nadine Norton; Hywel J Williams; Nigel M Williams; Ivan Nikolov; R Tzwetkova; S M Stambolova; Kieran C Murphy; Draga Toncheva; Anita Thapar; Michael C O'Donovan; Michael J Owen
Chromosome 22q11 deletions, velo-cardio-facial syndrome and early-onset psychosis. Molecular genetic study.
The British journal of psychiatry : the journal of mental science 2003;183():409-13.
2003: George Kirov; Lyudmila Georgieva; Nigel Williams; Ivan Nikolov; Nadine Norton; Draga Toncheva; Michael O'Donovan; Michael J Owen
Variation in the protocadherin gamma A gene cluster.
Genomics 2003;82(4):433-40.
2003: Hywel J Williams; Nigel Williams; Gillian Spurlock; Nadine Norton; Dobril Ivanov; Robin G McCreadie; Anna Preece; Val Sharkey; Sue Jones; Stanley Zammit; Ivan Nikolov; I Kehaiov; Anita Thapar; Kieran C Murphy; George Kirov; Michael J Owen; Michael C O'Donovan
Association between PRODH and schizophrenia is not confirmed.
Molecular psychiatry 2003;8(7):644-5.
2003: Hywel J Williams; Nigel Williams; Gillian Spurlock; Nadine Norton; Stanley Zammit; George Kirov; Michael J Owen; Michael C O'Donovan
Detailed analysis of PRODH and PsPRODH reveals no association with schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;120B(1):42-6.
2003: Lyudmila Georgieva; Ivan Nikolov; Nadezhda Poriazova; Gaynor Jones; Draga Toncheva; George Kirov; Michael J Owen
Genetic variation in the seven-pass transmembrane cadherin CELSR1: lack of association with schizophrenia.
Psychiatric genetics 2003;13(2):103-6.
2003: George Kirov; Lyudmila Georgieva; Ivan Nikolov; Stanley Zammit; Gaynor Jones; Nadezhda Poriazova; Todor Tolev; Richard Owen; Sue Jones; Michael J Owen
Association analysis of the HOPA12bp polymorphism in schizophrenia and manic depressive illness.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;118B(1):16-9.
2002: Albena Dimitrova; Lyudmila Georgieva; Ivan Nikolov; Nadezhda Poriazova; Stefan Krastev; Draga Toncheva; Michael J Owen; George Kirov
Major psychiatric disorders and the serotonin transporter gene (SLC6A4): family-based association studies.
Psychiatric genetics 2002;12(3):137-41.
2002: Nicholas J Bray; George Kirov; R J Owen; NJ Jacobsen; Lyudmila Georgieva; Hywel J Williams; Nadine Norton; Gillian Spurlock; Sue Jones; Stanley Zammit; Michael C O'Donovan; Michael J Owen
Screening the human protocadherin 8 (PCDH8) gene in schizophrenia.
Genes, brain, and behavior 2002;1(3):187-91.
2002: Nadine Norton; George Kirov; Stanley Zammit; Gaynor Jones; Susan Jones; Richard Owen; Michael Krawczak; Nigel M Williams; Michael C O'Donovan; Michael J Owen
Schizophrenia and functional polymorphisms in the MAOA and COMT genes: no evidence for association or epistasis.
American journal of medical genetics 2002;114(5):491-6.
2002: Nadine Norton; Nigel M Williams; Hywel J Williams; Gillian Spurlock; George Kirov; Derek W Morris; Bastiaan Hoogendoorn; Michael J Owen; Michael C O'Donovan
Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools.
Human genetics 2002;110(5):471-8.
2002: Lyudmila Georgieva; Albena Dimitrova; Ivan Nikolov; S Koleva; R Tsvetkova; Michael J Owen; Draga Toncheva; George Kirov
Dopamine transporter gene (DAT1) VNTR polymorphism in major psychiatric disorders: family-based association study in the Bulgarian population.
Acta psychiatrica Scandinavica 2002;105(5):396-9.
2002: Nigel M Williams; Gillian Spurlock; Nadine Norton; Hywel J Williams; Marian Hamshere; Michael Krawczak; George Kirov; Ivan Nikolov; Lyudmila Georgieva; Sue Jones; Alastair G Cardno; Michael C O'Donovan; Michael J Owen
Mutation screening and LD mapping in the VCFS deleted region of chromosome 22q11 in schizophrenia using a novel DNA pooling approach.
Molecular psychiatry 2002;7(10):1092-100.
2002: Pamela Sklar; Stacey B Gabriel; Melvin G McInnis; P Bennett; Y -M Lim; G Tsan; Stephen F Schaffner; George Kirov; I Jones; Michael J Owen; N Craddock; J. Raymond DePaulo; Eric S Lander
Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor.
Molecular psychiatry 2002;7(6):579-93.
2002: E O'Mahony; Aiden Corvin; R O'Connell; C Comerford; B Larsen; R Jones; Fiona McCandless; George Kirov; Alastair G Cardno; Nick Craddock; Michael Gill
Sibling pairs with affective disorders: resemblance of demographic and clinical features.
Psychological medicine 2002;32(1):55-61.
2002: Philip Bennett; Ricardo Segurado; Ian Jones; S Bort; Fiona McCandless; David Lambert; Jessica Heron; C Comerford; Fiona Middle; Aiden Corvin; G Pelios; George Kirov; B Larsen; T Mulcahy; Nigel Williams; R O'Connell; E O'Mahony; A Payne; Michael J Owen; Peter Holmans; Nick Craddock; Michael Gill
The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report.
Molecular psychiatry 2002;7(2):189-200.
2001: George Kirov; C A Lowry; M Stephens; S Oldfield; Michael C O'Donovan; S L Lightman; Michael J Owen
Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder.
Molecular psychiatry 2001;6(6):671-7.
2001: Pamela Sklar; Sibylle G Schwab; Nigel M Williams; Mark J Daly; Stephen F Schaffner; W Maier; Margot Albus; Mátyás Trixler; P Eichhammer; Bernard Lerer; Joachim Hallmayer; Nadine Norton; H Williams; Stanley Zammit; Alastair G Cardno; S Jones; G McCarthy; vihra milanova; George Kirov; M C O'Donovan; Eric S Lander; Michael J Owen; Dieter B Wildenauer
Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls.
Nature genetics 2001;28(2):126-8.
2000: Timothy Bowen; L Ashworth; George Kirov; Carol A Guy; Ian Richard Jones; Fiona McCandless; Nick Craddock; Michael C O'Donovan; Michael J Owen
No evidence of association from transmission disequilibrium analysis of the hKCa3 gene in bipolar disorder.
Bipolar disorders 2000;2(4):328-31.
2000: Bastiaan Hoogendoorn; Nadine Norton; George Kirov; Nigel Williams; Marian Hamshere; Gillian Spurlock; J Austin; M K Stephens; Paul R Buckland; Michael J Owen; Michael C O'Donovan
Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools.
Human genetics 2000;107(5):488-93.
2000: George Kirov; Nigel Williams; P Sham; Nick Craddock; Michael J Owen
Pooled genotyping of microsatellite markers in parent-offspring trios.
Genome research 2000;10(1):105-15.
1999: George Kirov; Ian Jones; Fiona McCandless; Nick Craddock; Michael J Owen
Family-based association studies of bipolar disorder with candidate genes involved in dopamine neurotransmission: DBH, DAT1, COMT, DRD2, DRD3 and DRD5.
Molecular psychiatry 1999;4(6):558-65.
1999: Timothy Bowen; George Kirov; Michael Gill; Gillian Spurlock; Homero Vallada; R M Murray; Peter McGuffin; DA Collier; Michael J Owen; Nick Craddock
Linkage studies of bipolar disorder with chromosome 18 markers.
American journal of medical genetics 1999;88(5):503-9.
1999: George Kirov; M Rees; Ian Jones; F MacCandless; Michael J Owen; Nick Craddock
Bipolar disorder and the serotonin transporter gene: a family-based association study.
Psychological medicine 1999;29(5):1249-54.
1999: George Kirov; R M Murray
Ethnic differences in the presentation of bipolar affective disorder.
European psychiatry : the journal of the Association of European Psychiatrists 1999;14(4):199-204.
1999: George Kirov; Michael J Owen; Ian Jones; Fiona McCandless; Nick Craddock
Tryptophan hydroxylase gene and manic-depressive illness.
Archives of general psychiatry 1999;56(1):98-9.
1998: George Kirov; Kieran C Murphy; M J Arranz; Ian Jones; F McCandles; H Kunugi; R M Murray; Peter McGuffin; DA Collier; Michael J Owen; Nick Craddock
Low activity allele of catechol-O-methyltransferase gene associated with rapid cycling bipolar disorder.
Molecular psychiatry 1998;3(4):342-5.
1998: R Kemp; George Kirov; B Everitt; P Hayward; Anthony David
Randomised controlled trial of compliance therapy. 18-month follow-up.
The British journal of psychiatry : the journal of mental science 1998;172():413-9.
1998: RAdka Kaneva; vihra milanova; Georgi Onchev; Vesela S Stoyanova; C H Chakarova; A Nikolova; Joachim Hallmayer; M Belemezova; T Milenska; George Kirov; Ivo Kremensky; Luba Kalaydjieva; Assen Jablensky
A linkage study of affective disorders in two Bulgarian Gypsy families: results for candidate regions on chromosomes 18 and 21.
Psychiatric genetics 1998;8(4):245-9.
1998: George Kirov; R Kemp; K Kirov; Anthony David
Religious faith after psychotic illness.
Psychopathology 1998;31(5):234-45.
1997: George Kirov; R Murray
The molecular genetics of schizophrenia: progress so far.
Molecular medicine today 1997;3(3):124-30.
1996: Homero Vallada; Nick Craddock; L Vasques; D Curtis; George Kirov; V Lauriano; Valentim Gentil; R Passos-Bueno; Robin M Murray; Mayana Zatz; Peter McGuffin; John F Powell; M Gill; Michael J Owen; D A Collier
Linkage studies in bipolar affective disorder with markers on chromosome 21.
Journal of affective disorders 1996;41(3):217-21.
1996: D A Collier; Gerald Stöber; T Li; A Heils; Marco Catalano; Daniela Di Bella; Maria J Arranz; Robin M Murray; Homero Vallada; Dominik Bengel; C R Müller; G W Roberts; Enrico Smeraldi; George Kirov; Pak Sham; Klaus-Peter Lesch
A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders.
Molecular psychiatry 1996;1(6):453-60.
1996: Maria J Arranz; D A Collier; Janet Munro; Pak Sham; George Kirov; M Sodhi; G Roberts; J Price; Monsheel Sodhi
Analysis of a structural polymorphism in the 5-HT2A receptor and clinical response to clozapine.
Neuroscience letters 1996;217(2-3):177-8.
1996: D A Collier; Monsheel Sodhi; Pak Sham; S Battersby; Homero Vallada; P Gill; KJ Aitchison; M Sodhi; T Li; G W Roberts; B Smith; J Morton; Robin M Murray; D Smith; George Kirov
The serotonin transporter is a potential susceptibility factor for bipolar affective disorder.
Neuroreport 1996;7(10):1675-9.
1996: George Kirov; P B Jones; I Harvey; Shon Lewis; B K Toone; Larry Rifkin; Pak Sham; Robin M Murray
Do obstetric complications cause the earlier age at onset in male than female schizophrenics?
Schizophrenia research 1996;20(1-2):117-24.
1994: George Kirov; P Jones; Shon Lewis
Prevalence of delusional misidentification syndromes.
Psychopathology 1994;27(3-5):148-9.