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Lee Kirsch

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Chemistry, Pharmaceutical

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Publications

TOP 3
Zhixin Zong; Lee E Kirsch
Studies on the instability of chlorhexidine, part I: kinetics and mechanisms.
Zhixin Zong; Jiang Qiu; Radaduen Tinmanee; Lee E Kirsch
Kinetic model for solid-state degradation of gabapentin.
Zhixin Zong; Eric J Munson; Raj Suryanarayanan; Dewey H Barich; Salil D Desai; Hong-Shian Huang; Aditya M Kaushal; Lee E Kirsch
The stabilizing effect of moisture on the solid-state degradation of gabapentin.

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All Publications

2012: Zhixin Zong; Lee E Kirsch
Studies on the instability of chlorhexidine, part I: kinetics and mechanisms.
Journal of pharmaceutical sciences 2012;101(7):2417-27.
2012: Zhixin Zong; Jiang Qiu; Radaduen Tinmanee; Lee E Kirsch
Kinetic model for solid-state degradation of gabapentin.
Journal of pharmaceutical sciences 2012;101(6):2123-33.
2011: Zhixin Zong; Eric J Munson; Raj Suryanarayanan; Dewey H Barich; Salil D Desai; Hong-Shian Huang; Aditya M Kaushal; Lee E Kirsch
The stabilizing effect of moisture on the solid-state degradation of gabapentin.
AAPS PharmSciTech 2011;12(3):924-31.
2009: Madhushree Y Gokhale; Lee E Kirsch
Glycosylation of aromatic amines III: Mechanistic implications of the pH-dependent glycosylation of various aromatic amines (kynurenine, 2'-aminoacetophenone, daptomycin, and sulfamethoxzaole).
Journal of pharmaceutical sciences 2009;98(12):4639-49.
2009: Madhushree Y Gokhale; Lee E Kirsch
Glycosylation of aromatic amines II: Kinetics and mechanisms of the hydrolytic reaction between kynurenine and glucose.
Journal of pharmaceutical sciences 2009;98(12):4616-28.
2009: Boontarika Chanvorachote; Ubonthip Nimmannit; Walaisiri Muangsiri; Lee E Kirsch
An evaluation of a fluorometric method for determining binding parameters of drug-carrier complexes using mathematical models based on total drug concentration.
Journal of fluorescence 2009;19(4):747-53.
2009: Beesan Tan; Himanshu Naik; In-Jin Jang; Kyung-Sang Yu; Lee E Kirsch; Chang-Sik Shin; J Carl Craft; Lawrence Fleckenstein
Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects.
Malaria journal 2009;8():304.
2009: Madhushree Y Gokhale; William R Kearney; Lee E Kirsch
Glycosylation of aromatic amines I: Characterization of reaction products and kinetic scheme.
AAPS PharmSciTech 2009;10(2):317-28.
2006: Walaisiri Muangsiri; Lee E Kirsch
The protein-binding and drug release properties of macromolecular conjugates containing daptomycin and dextran.
International journal of pharmaceutics 2006;315(1-2):30-43.
2005: Anjali B Joshi; Monali V Sawai; William R Kearney; Lee E Kirsch
Studies on the mechanism of aspartic acid cleavage and glutamine deamidation in the acidic degradation of glucagon.
Journal of pharmaceutical sciences 2005;94(9):1912-27.
2005: Walaisiri Muangsiri; William R Kearney; Lynn M Teesch; Lee E Kirsch
Studies on the reactions between daptomycin and glyceraldehyde.
International journal of pharmaceutics 2005;289(1-2):133-50.
2004: Anjali B Joshi; Lee E Kirsch
The estimation of glutaminyl deamidation and aspartyl cleavage rates in glucagon.
International journal of pharmaceutics 2004;273(1-2):213-9.
2004: Xiaoguang Zhang; Lee E Kirsch
Correlation of the thermal stability of phospholipid-based emulsions and the microviscosity measurements using fluorescence polarization.
Pharmaceutical development and technology 2004;9(2):219-27.
2003: Lida T Nguyen; John M Wiencek; Lee E Kirsch
Characterization methods for the physical stability of biopharmaceuticals.
PDA journal of pharmaceutical science and technology / PDA 2003;57(6):429-45.
2003: Xiaoguang Zhang; Lee E Kirsch
The physical stability of thermally-stressed phospholipid-based emulsions containing methyl, propyl and heptyl parabens as model drugs.
International journal of pharmaceutics 2003;265(1-2):133-40.
2003: Xiaoguang Zhang; Lee E Kirsch
An assessment of techniques for evaluating the physical stability of parenteral emulsions.
PDA journal of pharmaceutical science and technology / PDA 2003;57(4):300-15.
2002: Anjali B Joshi; Lee E Kirsch
The relative rates of glutamine and asparagine deamidation in glucagon fragment 22-29 under acidic conditions.
Journal of pharmaceutical sciences 2002;91(11):2331-45.
2001: Walaisiri Muangsiri; Lee E Kirsch
The kinetics of the alkaline degradation of daptomycin.
Journal of pharmaceutical sciences 2001;90(8):1066-75.
2001: Paul E Luner; Lee E Kirsch; S Majuru; E Oh; Anjali B Joshi; Dale Eric Wurster; M P Redmon
Preformulation studies on the S-isomer of oxybutynin hydrochloride, an Improved Chemical Entity (ICE).
Drug development and industrial pharmacy 2001;27(4):321-9.
2001: Lee E Kirsch; S Zhang; Walaisiri Muangsiri; M Redmon; Paul E Luner; Dale Eric Wurster
Development of a lyophilized formulation for (R,R)-formoterol (L)-tartrate.
Drug development and industrial pharmacy 2001;27(1):89-96.
2000: Anjali B Joshi; E Rus; Lee E Kirsch
The degradation pathways of glucagon in acidic solutions.
International journal of pharmaceutics 2000;203(1-2):115-25.
2000: Lee E Kirsch
Pharmaceutical container/closure integrity. VI: A report on the utility of liquid tracer methods for evaluating the microbial barrier properties of pharmaceutical packaging.
PDA journal of pharmaceutical science and technology / PDA 2000;54(4):305-14.
1999: Lee E Kirsch; L Nguyen; A M Kirsch; G Schmitt; M Koch; T Wertli; M Lehmann; G Schramm
Pharmaceutical container/closure integrity. V: An evaluation of the WILCO "LFC" method for leak testing pharmaceutical glass-stoppered vials.
PDA journal of pharmaceutical science and technology / PDA 1999;53(5):235-9.
1999: L T Nguyen; Walaisiri Muangsiri; R Schiere; D K Guazzo; Lee E Kirsch
Pharmaceutical container/closure integrity. IV: Development of an indirect correlation between vacuum decay leak measurement and microbial ingress.
PDA journal of pharmaceutical science and technology / PDA 1999;53(4):211-6.
1997: Y S Sihn; J K Guillory; Lee E Kirsch
Quantitation of taurolidine decomposition in polymer solutions by chromotropic acid formaldehyde assay method.
Journal of pharmaceutical and biomedical analysis 1997;16(4):643-50.
1997: Lee E Kirsch; Y S Sihn
The effect of polyvinylpyrrolidine on the stability of taurolidine.
Pharmaceutical development and technology 1997;2(4):345-56.
1997: Lee E Kirsch; L Nguyen; R Gerth
Pharmaceutical container/closure integrity. III: Validation of the helium leak rate method for rigid pharmaceutical containers.
PDA journal of pharmaceutical science and technology / PDA 1997;51(5):203-7.
1997: Lee E Kirsch; L Nguyen; C S Moeckly; R Gerth
Pharmaceutical container/closure integrity. II: The relationship between microbial ingress and helium leak rates in rubber-stoppered glass vials.
PDA journal of pharmaceutical science and technology / PDA 1997;51(5):195-202.
1997: Lee E Kirsch; L Nguyen; C S Moeckly
Pharmaceutical container/closure integrity. I: Mass spectrometry-based helium leak rate detection for rubber-stoppered glass vials.
PDA journal of pharmaceutical science and technology / PDA 1997;51(5):187-94.