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Marc Kirschner

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Living Beings

Chemicals & Drugs

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Anatomy

Procedures

Molecular Cloning

Phenomena

Phosphorylation

Physiology

Cell Cycle

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Co-Publications
Name
10
King, Randall
8
Lustig, KD
8
Ho, Hsin-Yi Henry
8
Rohatgi, Rajat
7
Salic, Adrian
6
Stukenberg, Todd
6
Yu, H
6
Gygi, Steven
6
Ma, Le
6
Lee, Tina
5
McGarry, TJ
5
Murray, Andrew
5
Lebensohn, Andres
5
Lee, Ethan
5
Ayad, Nagi

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Publications

TOP 3
Lebensohn Andres M; Kirschner Marc W
Activation of the WAVE complex by coincident signals controls actin assembly.
Tzur Amit; Kafri Ran; LeBleu Valerie S; Lahav Galit; Kirschner Marc W
Cell growth and size homeostasis in proliferating animal cells.
Jorgensen Paul; Steen Judith A J; Steen Hanno; Kirschner Marc W
The mechanism and pattern of yolk consumption provide insight into embryonic nutrition in Xenopus.

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All Publications

2009: Lebensohn Andres M; Kirschner Marc W
Activation of the WAVE complex by coincident signals controls actin assembly.
Molecular cell 2009;36(3):512-24.
2009: Tzur Amit; Kafri Ran; LeBleu Valerie S; Lahav Galit; Kirschner Marc W
Cell growth and size homeostasis in proliferating animal cells.
Science (New York, N.Y.) 2009;325(5937):167-71.
2009: Jorgensen Paul; Steen Judith A J; Steen Hanno; Kirschner Marc W
The mechanism and pattern of yolk consumption provide insight into embryonic nutrition in Xenopus.
Development (Cambridge, England) 2009;136(9):1539-48.
2009: Singh Sasha; Springer Michael; Steen Judith; Kirschner Marc W; Steen Hanno
FLEXIQuant: a novel tool for the absolute quantification of proteins, and the simultaneous identification and quantification of potentially modified peptides.
Journal of proteome research 2009;8(5):2201-10.
2009: Merbl Yifat; Kirschner Marc W
Large-scale detection of ubiquitination substrates using cell extracts and protein microarrays.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2543-8.
2007: Milo Ron; Hou Jennifer H; Springer Michael; Brenner Michael P; Kirschner Marc W
The relationship between evolutionary and physiological variation in hemoglobin.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(43):16998-7003.
2007: Weiner Orion D; Marganski William A; Wu Lani F; Altschuler Steven J; Kirschner Marc W
An actin-based wave generator organizes cell motility.
PLoS biology 2007;5(9):e221.
2007: Reddy S K; Rape M; Margansky W A; Kirschner M W
Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation.
Nature 2007;446(7138):921-5.
2007: Stegmeier Frank; Rape Michael; Draviam Viji M; Nalepa Grzegorz; Sowa Mathew E; Ang Xiaolu L; McDonald E Robert; Li Mamie Z; Hannon Gregory J; Sorger Peter K; Kirschner Marc W; Harper J Wade; Elledge Stephen J
Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
Nature 2007;446(7138):876-81.
2007: Wang Ruoning; He Guangan; Nelman-Gonzalez Mayra; Ashorn Cheryl L; Gallick Gary E; Stukenberg P Todd; Kirschner Marc W; Kuang Jian
Regulation of Cdc25C by ERK-MAP kinases during the G2/M transition.
Cell 2007;128(6):1119-32.
2006: Kirschner Marc W
Obituary: Reinhart Heinrich (1946-2006).
Nature 2006;444(7120):700.
2006: Peterson Jeffrey R; Lebensohn Andres M; Pelish Henry E; Kirschner Marc W
Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components.
Chemistry & biology 2006;13(4):443-52.
2006: Weiner Orion D; Rentel Maike C; Ott Alex; Brown Glenn E; Jedrychowski Mark; Yaffe Michael B; Gygi Steven P; Cantley Lewis C; Bourne Henry R; Kirschner Marc W
Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis.
PLoS biology 2006;4(2):e38.
2006: Rape Michael; Reddy Sashank K; Kirschner Marc W
The processivity of multiubiquitination by the APC determines the order of substrate degradation.
Cell 2006;124(1):89-103.
2006: Steen Hanno; Jebanathirajah Judith A; Rush John; Morrice Nicolas; Kirschner Marc W
Phosphorylation analysis by mass spectrometry: myths, facts, and the consequences for qualitative and quantitative measurements.
Molecular & cellular proteomics : MCP 2006;5(1):172-81.
2006: Ho Hsin-Yi Henry; Rohatgi Rajat; Lebensohn Andres M; Kirschner Marc W
In vitro reconstitution of cdc42-mediated actin assembly using purified components.
Methods in enzymology 2006;406():174-90.
2006: Lebensohn Andres M; Ma Le; Ho Hsin-Yi Henry; Kirschner Marc W
Cdc42 and PI(4,5)P2-induced actin assembly in Xenopus egg extracts.
Methods in enzymology 2006;406():156-73.
2005: Kwan Kristen M; Kirschner Marc W
A microtubule-binding Rho-GEF controls cell morphology during convergent extension of Xenopus laevis.
Development (Cambridge, England) 2005;132(20):4599-610.
2005: Viadiu Hector; Stemmann Olaf; Kirschner Marc W; Walz Thomas
Domain structure of separase and its binding to securin as determined by EM.
Nature structural & molecular biology 2005;12(6):552-3.
2005: Kirschner Marc W
The meaning of systems biology.
Cell 2005;121(4):503-4.
2005: Rankin Susannah; Ayad Nagi G; Kirschner Marc W
Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates.
Molecular cell 2005;18(2):185-200.
2005: Steen Hanno; Jebanathirajah Judith A; Springer Michael; Kirschner Marc W
Stable isotope-free relative and absolute quantitation of protein phosphorylation stoichiometry by MS.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):3948-53.
2005: Ayad Nagi G; Rankin Susannah; Ooi Danny; Rape Michael; Kirschner Marc W
Identification of ubiquitin ligase substrates by in vitro expression cloning.
Methods in enzymology 2005;399():404-14.
2004: Rape Michael; Kirschner Marc W
Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.
Nature 2004;432(7017):588-95.
2004: Margalit Danielle N; Romberg Laura; Mets Rebecca B; Hebert Alan M; Mitchison Timothy J; Kirschner Marc W; RayChaudhuri Debabrata
Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11821-6.
2004: Peterson Jeffrey R; Bickford Lincoln C; Morgan David; Kim Annette S; Ouerfelli Ouathek; Kirschner Marc W; Rosen Michael K
Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
Nature structural & molecular biology 2004;11(8):747-55.
2004: Ho Hsin-Yi Henry; Rohatgi Rajat; Lebensohn Andres M; Le Ma; Li Jiaxu; Gygi Steven P; Kirschner Marc W
Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex.
Cell 2004;118(2):203-16.
2004: Martinez-Quiles Narcisa; Ho Hsin-Yi Henry; Kirschner Marc W; Ramesh Narayanaswamy; Geha Raif S
Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP.
Molecular and cellular biology 2004;24(12):5269-80.
2004: Gautreau Alexis; Ho Hsin-yi H; Li Jiaxu; Steen Hanno; Gygi Steven P; Kirschner Marc W
Purification and architecture of the ubiquitous Wave complex.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4379-83.
2004: Wei Wenyi; Ayad Nagi G; Wan Yong; Zhang Guo-Jun; Kirschner Marc W; Kaelin William G
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex.
Nature 2004;428(6979):194-8.
2004: Song Min Sup; Song Su Jeong; Ayad Nagi G; Chang Jin Sook; Lee Joo Hyun; Hong Hyun Kyung; Lee Ho; Choi Naeyun; Kim Jhingook; Kim Hojoong; Kim Jin Woo; Choi Eui-Ju; Kirschner Marc W; Lim Dae-Sik
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex.
Nature cell biology 2004;6(2):129-37.
2003: Lee Ethan; Salic Adrian; Krüger Roland; Heinrich Reinhart; Kirschner Marc W
The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway.
PLoS biology 2003;1(1):E10.
2003: Yan Catherine; Martinez-Quiles Narcisa; Eden Sharon; Shibata Tomoyuki; Takeshima Fuminao; Shinkura Reiko; Fujiwara Yuko; Bronson Roderick; Snapper Scott B; Kirschner Marc W; Geha Raif; Rosen Fred S; Alt Frederick W
WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility.
The EMBO journal 2003;22(14):3602-12.
2003: Gerber Scott A; Rush John; Stemman Olaf; Kirschner Marc W; Gygi Steven P
Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(12):6940-5.
2003: Osterfield Miriam; Kirschner Marc W; Flanagan John G
Graded positional information: interpretation for both fate and guidance.
Cell 2003;113(4):425-8.
2003: Kwan Kristen M; Kirschner Marc W
Xbra functions as a switch between cell migration and convergent extension in the Xenopus gastrula.
Development (Cambridge, England) 2003;130(9):1961-72.
2003: Ayad Nagi G; Rankin Susannah; Murakami Monica; Jebanathirajah Judith; Gygi Steven; Kirschner Marc W
Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC.
Cell 2003;113(1):101-13.
2003: Chabes Anna Lena; Pfleger Cathie M; Kirschner Marc W; Thelander Lars
Mouse ribonucleotide reductase R2 protein: a new target for anaphase-promoting complex-Cdh1-mediated proteolysis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3925-9.
2003: Collavin Licio; Kirschner Marc W
The secreted Frizzled-related protein Sizzled functions as a negative feedback regulator of extreme ventral mesoderm.
Development (Cambridge, England) 2003;130(4):805-16.
2002: Holmen Sheri L; Salic Adrian; Zylstra Cassandra R; Kirschner Marc W; Williams Bart O
A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling.
The Journal of biological chemistry 2002;277(38):34727-35.
2002: Eden Sharon; Rohatgi Rajat; Podtelejnikov Alexandre V; Mann Matthias; Kirschner Marc W
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck.
Nature 2002;418(6899):790-3.
2002: Weiner Orion D; Neilsen Paul O; Prestwich Glenn D; Kirschner Marc W; Cantley Lewis C; Bourne Henry R
A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity.
Nature cell biology 2002;4(7):509-13.
2002: Georgi Ann B; Stukenberg P Todd; Kirschner Marc W
Timing of events in mitosis.
Current biology : CB 2002;12(2):105-14.
2001: Stemmann O; Zou H; Gerber S A; Gygi S P; Kirschner M W
Dual inhibition of sister chromatid separation at metaphase.
Cell 2001;107(6):715-26.
2001: Wan Y; Liu X; Kirschner M W
The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction.
Molecular cell 2001;8(5):1027-39.
2001: Wan Y; Kirschner M W
Identification of multiple CDH1 homologues in vertebrates conferring different substrate specificities.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13066-71.
2001: Davis R L; Turner D L; Evans L M; Kirschner M W
Molecular targets of vertebrate segmentation: two mechanisms control segmental expression of Xenopus hairy2 during somite formation.
Developmental cell 2001;1(4):553-65.
2001: Pfleger C M; Lee E; Kirschner M W
Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex.
Genes & development 2001;15(18):2396-407.
2001: Peterson J R; Lokey R S; Mitchison T J; Kirschner M W
A chemical inhibitor of N-WASP reveals a new mechanism for targeting protein interactions.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10624-9.
2001: Ho H Y; Rohatgi R; Ma L; Kirschner M W
CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11306-11.
2001: Lee E; Salic A; Kirschner M W
Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon.
The Journal of cell biology 2001;154(5):983-93.
2001: Pfleger C M; Salic A; Lee E; Kirschner M W
Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1.
Genes & development 2001;15(14):1759-64.
2001: Rohatgi R; Nollau P; Ho H Y; Kirschner M W; Mayer B J
Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway.
The Journal of biological chemistry 2001;276(28):26448-52.
2000: Rohatgi R; Ho H Y; Kirschner M W
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate.
The Journal of cell biology 2000;150(6):1299-310.
2000: Chen F; Ma L; Parrini M C; Mao X; Lopez M; Wu C; Marks P W; Davidson L; Kwiatkowski D J; Kirchhausen T; Orkin S H; Rosen F S; Mayer B J; Kirschner M W; Alt F W
Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability.
Current biology : CB 2000;10(13):758-65.
2000: Salic A; Lee E; Mayer L; Kirschner M W
Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts.
Molecular cell 2000;5(3):523-32.
2000: Pfleger C M; Kirschner M W
The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1.
Genes & development 2000;14(6):655-65.
2000: Luo X; Fang G; Coldiron M; Lin Y; Yu H; Kirschner M W; Wagner G
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20.
Nature structural biology 2000;7(3):224-9.
2000: Davis R L; Kirschner M W
The fate of cells in the tailbud of Xenopus laevis.
Development (Cambridge, England) 2000;127(2):255-67.
1999: Fang G; Yu H; Kirschner M W
Control of mitotic transitions by the anaphase-promoting complex.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1999;354(1389):1583-90.
1999: Zou H; McGarry T J; Bernal T; Kirschner M W
Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis.
Science (New York, N.Y.) 1999;285(5426):418-22.
1999: Rohatgi R; Ma L; Miki H; Lopez M; Kirchhausen T; Takenawa T; Kirschner M W
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly.
Cell 1999;97(2):221-31.
1999: Philpott A; Tsai L; Kirschner M W
Neuronal differentiation and patterning in Xenopus: the role of cdk5 and a novel activator xp35.2.
Developmental biology 1999;207(1):119-32.
1998: Ma L; Rohatgi R; Kirschner M W
The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15362-7.
1998: Mead P E; Zhou Y; Lustig K D; Huber T L; Kirschner M W; Zon L I
Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(19):11251-6.
1998: Fang G; Yu H; Kirschner M W
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1.
Molecular cell 1998;2(2):163-71.
1998: Kroll K L; Salic A N; Evans L M; Kirschner M W
Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation.
Development (Cambridge, England) 1998;125(16):3247-58.
1998: Fang G; Yu H; Kirschner M W
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation.
Genes & development 1998;12(12):1871-83.
1998: McGarry T J; Kirschner M W
Geminin, an inhibitor of DNA replication, is degraded during mitosis.
Cell 1998;93(6):1043-53.
1998: Zhou B B; Li H; Yuan J; Kirschner M W
Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6785-90.
1998: Ma L; Cantley L C; Janmey P A; Kirschner M W
Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts.
The Journal of cell biology 1998;140(5):1125-36.
1998: Yu H; Peters J M; King R W; Page A M; Hieter P; Kirschner M W
Identification of a cullin homology region in a subunit of the anaphase-promoting complex.
Science (New York, N.Y.) 1998;279(5354):1219-22.
1997: Salic A N; Kroll K L; Evans L M; Kirschner M W
Sizzled: a secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos.
Development (Cambridge, England) 1997;124(23):4739-48.
1997: Yaffe M B; Schutkowski M; Shen M; Zhou X Z; Stukenberg P T; Rahfeld J U; Xu J; Kuang J; Kirschner M W; Fischer G; Cantley L C; Lu K P
Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism.
Science (New York, N.Y.) 1997;278(5345):1957-60.
1997: Cryns V L; Byun Y; Rana A; Mellor H; Lustig K D; Ghanem L; Parker P J; Kirschner M W; Yuan J
Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis. Identification by a novel, small pool expression cloning strategy.
The Journal of biological chemistry 1997;272(47):29449-53.
1997: Yew P R; Kirschner M W
Proteolysis and DNA replication: the CDC34 requirement in the Xenopus egg cell cycle.
Science (New York, N.Y.) 1997;277(5332):1672-6.
1997: King R W; Lustig K D; Stukenberg P T; McGarry T J; Kirschner M W
Expression cloning in the test tube.
Science (New York, N.Y.) 1997;277(5328):973-4.
1997: Rankin S; Kirschner M W
The surface contraction waves of Xenopus eggs reflect the metachronous cell-cycle state of the cytoplasm.
Current biology : CB 1997;7(6):451-4.
1997: Philpott A; Porro E B; Kirschner M W; Tsai L H
The role of cyclin-dependent kinase 5 and a novel regulatory subunit in regulating muscle differentiation and patterning.
Genes & development 1997;11(11):1409-21.
1997: Stukenberg P T; Lustig K D; McGarry T J; King R W; Kuang J; Kirschner M W
Systematic identification of mitotic phosphoproteins.
Current biology : CB 1997;7(5):338-48.
1997: Lustig K D; Stukenberg P T; McGarry T J; King R W; Cryns V L; Mead P E; Zon L I; Yuan J; Kirschner M W
Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development.
Methods in enzymology 1997;283():83-99.
1996: Lustig K D; Kroll K L; Sun E E; Kirschner M W
Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation.
Development (Cambridge, England) 1996;122(12):4001-12.
1996: King R W; Deshaies R J; Peters J M; Kirschner M W
How proteolysis drives the cell cycle.
Science (New York, N.Y.) 1996;274(5293):1652-9.
1996: Peters J M; King R W; Höög C; Kirschner M W
Identification of BIME as a subunit of the anaphase-promoting complex.
Science (New York, N.Y.) 1996;274(5290):1199-201.
1996: Lustig K D; Kroll K; Sun E; Ramos R; Elmendorf H; Kirschner M W
A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation.
Development (Cambridge, England) 1996;122(10):3275-82.
1996: King R W; Glotzer M; Kirschner M W
Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates.
Molecular biology of the cell 1996;7(9):1343-57.
1996: Yu H; King R W; Peters J M; Kirschner M W
Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation.
Current biology : CB 1996;6(4):455-66.
1996: Lee T H; Kirschner M W
An inhibitor of p34cdc2/cyclin B that regulates the G2/M transition in Xenopus extracts.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):352-6.
1995: Kinoshita N; Minshull J; Kirschner M W
The identification of two novel ligands of the FGF receptor by a yeast screening method and their activity in Xenopus development.
Cell 1995;83(4):621-30.
1995: Jackson P K; Chevalier S; Philippe M; Kirschner M W
Early events in DNA replication require cyclin E and are blocked by p21CIP1.
The Journal of cell biology 1995;130(4):755-69.
1995: Lustig K D; Kirschner M W
Use of an oocyte expression assay to reconstitute inductive signaling.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(14):6234-8.
1995: Sabry J; O'Connor T P; Kirschner M W
Axonal transport of tubulin in Ti1 pioneer neurons in situ.
Neuron 1995;14(6):1247-56.
1995: King R W; Peters J M; Tugendreich S; Rolfe M; Hieter P; Kirschner M W
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B.
Cell 1995;81(2):279-88.
1995: Tanaka E; Ho T; Kirschner M W
The role of microtubule dynamics in growth cone motility and axonal growth.
The Journal of cell biology 1995;128(1-2):139-55.
1995: Tanaka E; Kirschner M W
The role of microtubules in growth cone turning at substrate boundaries.
The Journal of cell biology 1995;128(1-2):127-37.
1994: Drechsel D N; Kirschner M W
The minimum GTP cap required to stabilize microtubules.
Current biology : CB 1994;4(12):1053-61.
1994: King R W; Jackson P K; Kirschner M W
Mitosis in transition.
Cell 1994;79(4):563-71.
1994: Kirschner M W; Marincola E; Teisberg E O
The role of biomedical research in health care reform.
Science (New York, N.Y.) 1994;266(5182):49-51.
1994: Lee T H; Turck C; Kirschner M W
Inhibition of cdc2 activation by INH/PP2A.
Molecular biology of the cell 1994;5(3):323-38.
1993: Booher R N; Deshaies R J; Kirschner M W
Properties of Saccharomyces cerevisiae wee1 and its differential regulation of p34CDC28 in response to G1 and G2 cyclins.
The EMBO journal 1993;12(9):3417-26.
1993: Amaya E; Stein P A; Musci T J; Kirschner M W
FGF signalling in the early specification of mesoderm in Xenopus.
Development (Cambridge, England) 1993;118(2):477-87.
1992: Drechsel D N; Hyman A A; Cobb M H; Kirschner M W
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.
Molecular biology of the cell 1992;3(10):1141-54.
1992: Solomon M J; Lee T; Kirschner M W
Role of phosphorylation in p34cdc2 activation: identification of an activating kinase.
Molecular biology of the cell 1992;3(1):13-27.
1991: Butner K A; Kirschner M W
Tau protein binds to microtubules through a flexible array of distributed weak sites.
The Journal of cell biology 1991;115(3):717-30.
1991: Tanaka E M; Kirschner M W
Microtubule behavior in the growth cones of living neurons during axon elongation.
The Journal of cell biology 1991;115(2):345-63.
1991: Gautier J; Solomon M J; Booher R N; Bazan J F; Kirschner M W
cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.
Cell 1991;67(1):197-211.
1991: Amaya E; Musci T J; Kirschner M W
Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos.
Cell 1991;66(2):257-70.
1991: Murray A W; Kirschner M W
What controls the cell cycle?
Scientific American 1991;264(3):56-63.
1991: Lee T H; Solomon M J; Mumby M C; Kirschner M W
INH, a negative regulator of MPF, is a form of protein phosphatase 2A.
Cell 1991;64(2):415-23.
1991: Glotzer M; Murray A W; Kirschner M W
Cyclin is degraded by the ubiquitin pathway.
Nature 1991;349(6305):132-8.
1991: Solomon M J; Gautier J; Lee T; Kirschner M W
Control of p34cdc2 activation.
Cold Spring Harbor symposia on quantitative biology 1991;56():427-35.
1990: Musci T J; Amaya E; Kirschner M W
Regulation of the fibroblast growth factor receptor in early Xenopus embryos.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8365-9.
1990: Solomon M J; Glotzer M; Lee T H; Philippe M; Kirschner M W
Cyclin activation of p34cdc2.
Cell 1990;63(5):1013-24.
1990: Ward G E; Kirschner M W
Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C.
Cell 1990;61(4):561-77.
1989: Murray A W; Kirschner M W
Dominoes and clocks: the union of two views of the cell cycle.
Science (New York, N.Y.) 1989;246(4930):614-21.
1989: Kimelman D; Kirschner M W
An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes.
Cell 1989;59(4):687-96.
1989: Murray A W; Solomon M J; Kirschner M W
The role of cyclin synthesis and degradation in the control of maturation promoting factor activity.
Nature 1989;339(6222):280-6.
1989: Murray A W; Kirschner M W
Cyclin synthesis drives the early embryonic cell cycle.
Nature 1989;339(6222):275-80.
1988: Kimelman D; Abraham J A; Haaparanta T; Palisi T M; Kirschner M W
The presence of fibroblast growth factor in the frog egg: its role as a natural mesoderm inducer.
Science (New York, N.Y.) 1988;242(4881):1053-6.
1988: Cyert M S; Scherson T; Kirschner M W
Monoclonal antibodies specific for thiophosphorylated proteins recognize Xenopus MPF.
Developmental biology 1988;129(1):209-16.
1988: Cyert M S; Kirschner M W
Regulation of MPF activity in vitro.
Cell 1988;53(2):185-95.
1988: Koshland D E; Mitchison T J; Kirschner M W
Polewards chromosome movement driven by microtubule depolymerization in vitro.
Nature 1988;331(6156):499-504.
1988: Huitorel P; Kirschner M W
The polarity and stability of microtubule capture by the kinetochore.
The Journal of cell biology 1988;106(1):151-9.
1987: Wolin S L; Krohne G; Kirschner M W
A new lamin in Xenopus somatic tissues displays strong homology to human lamin A.
The EMBO journal 1987;6(12):3809-18.
1987: Krohne G; Wolin S L; McKeon F D; Franke W W; Kirschner M W
Nuclear lamin LI of Xenopus laevis: cDNA cloning, amino acid sequence and binding specificity of a member of the lamin B subfamily.
The EMBO journal 1987;6(12):3801-8.
1987: Gard D L; Kirschner M W
Microtubule assembly in cytoplasmic extracts of Xenopus oocytes and eggs.
The Journal of cell biology 1987;105(5):2191-201.
1987: Gard D L; Kirschner M W
A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end.
The Journal of cell biology 1987;105(5):2203-15.

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