Carsten Kirschning

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Physiology

Anatomy

Cell Line

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Siegemund Sabine; Hartl Andrea; von Buttlar Heiner; Dautel Franziska; Raue Rüdiger; Freudenberg Marina A; Fejer György; Büttner Mathias; Köhler Gabriele; Kirschning Carsten J; Sparwasser Tim; Alber Gottfried
Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis.
Rad Roland; Ballhorn Wibke; Voland Petra; Eisenächer Katharina; Mages Jörg; Rad Lena; Ferstl Ruth; Lang Roland; Wagner Hermann; Schmid Roland M; Bauer Stefan; Prinz Christian; Kirschning Carsten J; Krug Anne
Extracellular and intracellular pattern recognition receptors cooperate in the recognition of Helicobacter pylori.
Schädlich Lysann; Senger Tilo; Kirschning Carsten J; Müller Martin; Gissmann Lutz
Refining HPV 16 L1 purification from E. coli: reducing endotoxin contaminations and their impact on immunogenicity.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Carsten Kirschning (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Siegemund Sabine; Hartl Andrea; von Buttlar Heiner; Dautel Franziska; Raue Rüdiger; Freudenberg Marina A; Fejer György; Büttner Mathias; Köhler Gabriele; Kirschning Carsten J; Sparwasser Tim; Alber Gottfried
Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis.
Journal of virology 2009;83(18):9411-22.
2009: Rad Roland; Ballhorn Wibke; Voland Petra; Eisenächer Katharina; Mages Jörg; Rad Lena; Ferstl Ruth; Lang Roland; Wagner Hermann; Schmid Roland M; Bauer Stefan; Prinz Christian; Kirschning Carsten J; Krug Anne
Extracellular and intracellular pattern recognition receptors cooperate in the recognition of Helicobacter pylori.
Gastroenterology 2009;136(7):2247-57.
2009: Schädlich Lysann; Senger Tilo; Kirschning Carsten J; Müller Martin; Gissmann Lutz
Refining HPV 16 L1 purification from E. coli: reducing endotoxin contaminations and their impact on immunogenicity.
Vaccine 2009;27(10):1511-22.
2009: Werninghaus Kerstin; Babiak Anna; Gross Olaf; Hölscher Christoph; Dietrich Harald; Agger Else Marie; Mages Jörg; Mocsai Attila; Schoenen Hanne; Finger Katrin; Nimmerjahn Falk; Brown Gordon D; Kirschning Carsten; Heit Antje; Andersen Peter; Wagner Hermann; Ruland Jürgen; Lang Roland
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.
The Journal of experimental medicine 2009;206(1):89-97.
2009: Ferstl Ruth; Spiller Stephan; Fichte Sylvia; Dreher Stefan; Kirschning Carsten J
Experimental models of acute infection and Toll-like receptor driven septic shock.
Methods in molecular biology (Clifton, N.J.) 2009;517():313-27.
2008: Schmitz Frank; Heit Antje; Dreher Stefan; Eisenächer Katharina; Mages Jörg; Haas Tobias; Krug Anne; Janssen Klaus-Peter; Kirschning Carsten J; Wagner Hermann
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells.
European journal of immunology 2008;38(11):2981-92.
2008: Klein Matthias; Obermaier Bianca; Angele Barbara; Pfister Hans-Walter; Wagner Hermann; Koedel Uwe; Kirschning Carsten J
Innate immunity to pneumococcal infection of the central nervous system depends on toll-like receptor (TLR) 2 and TLR4.
The Journal of infectious diseases 2008;198(7):1028-36.
2008: Cramer Jakob P; Lepenies Bernd; Kamena Faustin; Hölscher Christoph; Freudenberg Marina A; Burchard Gerd D; Wagner Hermann; Kirschning Carsten J; Liu Xinyu; Seeberger Peter H; Jacobs Thomas
MyD88/IL-18-dependent pathways rather than TLRs control early parasitaemia in non-lethal Plasmodium yoelii infection.
Microbes and infection / Institut Pasteur 2008;10(12-13):1259-65.
2008: Spiller Stephan; Elson Greg; Ferstl Ruth; Dreher Stefan; Mueller Thomas; Freudenberg Marina; Daubeuf Bruno; Wagner Hermann; Kirschning Carsten J
TLR4-induced IFN-gamma production increases TLR2 sensitivity and drives Gram-negative sepsis in mice.
The Journal of experimental medicine 2008;205(8):1747-54.
2008: Gratz Nina; Siller Maria; Schaljo Barbara; Pirzada Zaid A; Gattermeier Irene; Vojtek Ivo; Kirschning Carsten J; Wagner Hermann; Akira Shizuo; Charpentier Emmanuelle; Kovarik Pavel
Group A streptococcus activates type I interferon production and MyD88-dependent signaling without involvement of TLR2, TLR4, and TLR9.
The Journal of biological chemistry 2008;283(29):19879-87.
2008: Peiser Matthias; Koeck Juliana; Kirschning Carsten J; Wittig Burghardt; Wanner Reinhard
Human Langerhans cells selectively activated via Toll-like receptor 2 agonists acquire migratory and CD4+T cell stimulatory capacity.
Journal of leukocyte biology 2008;83(5):1118-27.
2008: Hölscher Christoph; Reiling Norbert; Schaible Ulrich E; Hölscher Alexandra; Bathmann Clara; Korbel Daniel; Lenz Insa; Sonntag Tanja; Kröger Svenja; Akira Shizuo; Mossmann Horst; Kirschning Carsten J; Wagner Hermann; Freudenberg Marina; Ehlers Stefan
Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9.
European journal of immunology 2008;38(3):680-94.
2008: Lepenies Bernd; Cramer Jakob P; Burchard Gerd D; Wagner Hermann; Kirschning Carsten J; Jacobs Thomas
Induction of experimental cerebral malaria is independent of TLR2/4/9.
Medical microbiology and immunology 2008;197(1):39-44.
2007: Daubeuf Bruno; Mathison John; Spiller Stephan; Hugues Stephanie; Herren Suzanne; Ferlin Walter; Kosco-Vilbois Marie; Wagner Hermann; Kirschning Carsten J; Ulevitch Richard; Elson Greg
TLR4/MD-2 monoclonal antibody therapy affords protection in experimental models of septic shock.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):6107-14.
2007: Geisel Julia; Kahl Frauke; Müller Martina; Wagner Hermann; Kirschning Carsten J; Autenrieth Ingo B; Frick Julia-Stefanie
IL-6 and maturation govern TLR2 and TLR4 induced TLR agonist tolerance and cross-tolerance in dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):5811-8.
2007: Rupprecht Tobias A; Kirschning Carsten J; Popp Bernadette; Kastenbauer Stefan; Fingerle Volker; Pfister Hans-Walter; Koedel Uwe
Borrelia garinii induces CXCL13 production in human monocytes through Toll-like receptor 2.
Infection and immunity 2007;75(9):4351-6.
2007: Koedel Uwe; Merbt Ulrike Michaela; Schmidt Caroline; Angele Barbara; Popp Bernadette; Wagner Hermann; Pfister Hans-Walter; Kirschning Carsten J
Acute brain injury triggers MyD88-dependent, TLR2/4-independent inflammatory responses.
The American journal of pathology 2007;171(1):200-13.
2007: Lech M; Garlanda C; Mantovani A; Kirschning C J; Schlöndorff D; Anders H-J
Different roles of TiR8/Sigirr on toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells.
Kidney international 2007;72(2):182-92.
2007: Merx Sabine; Neumaier Michael; Wagner Hermann; Kirschning Carsten J; Ahmad-Nejad Parviz
Characterization and investigation of single nucleotide polymorphisms and a novel TLR2 mutation in the human TLR2 gene.
Human molecular genetics 2007;16(10):1225-32.
2007: Spiller Stephan; Dreher Stefan; Meng Guangxun; Grabiec Alina; Thomas Winston; Hartung Thomas; Pfeffer Klaus; Hochrein Hubertus; Brade Helmut; Bessler Wolfgang; Wagner Hermann; Kirschning Carsten J
Cellular recognition of trimyristoylated peptide or enterobacterial lipopolysaccharide via both TLR2 and TLR4.
The Journal of biological chemistry 2007;282(18):13190-8.
2007: Klein Matthias; Schmidt Caroline; Kastenbauer Stefan; Paul Robert; Kirschning Carsten J; Wagner Hermann; Popp Bernadette; Pfister Hans-Walter; Koedel Uwe
MyD88-dependent immune response contributes to hearing loss in experimental pneumococcal meningitis.
The Journal of infectious diseases 2007;195(8):1189-93.
2007: Zhu Xinsheng; Bagchi Aranya; Zhao Huailong; Kirschning Carsten J; Hajjar Roger J; Chao Wei; Hellman Judith; Schmidt Ulrich
Toll-like receptor 2 activation by bacterial peptidoglycan-associated lipoprotein activates cardiomyocyte inflammation and contractile dysfunction.
Critical care medicine 2007;35(3):886-92.
2007: Krishnan Lakshmi; Gurnani Komal; Dicaire Chantal J; van Faassen Henk; Zafer Ahmed; Kirschning Carsten J; Sad Subash; Sprott G Dennis
Rapid clonal expansion and prolonged maintenance of memory CD8+ T cells of the effector (CD44highCD62Llow) and central (CD44highCD62Lhigh) phenotype by an archaeosome adjuvant independent of TLR2.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2396-406.
2006: Frick Julia S; Zahir Naima; Müller Martina; Kahl Frauke; Bechtold Oliver; Lutz Manfred B; Kirschning Carsten J; Reimann Jörg; Jilge Burghard; Bohn Erwin; Autenrieth Ingo B
Colitogenic and non-colitogenic commensal bacteria differentially trigger DC maturation and Th cell polarization: an important role for IL-6.
European journal of immunology 2006;36(6):1537-47.
2006: Prinz Marco; Garbe Folker; Schmidt Hauke; Mildner Alexander; Gutcher Ilona; Wolter Karina; Piesche Matthias; Schroers Roland; Weiss Elisabeth; Kirschning Carsten J; Rochford Christian D P; Brück Wolfgang; Becher Burkhard
Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis.
The Journal of clinical investigation 2006;116(2):456-64.
2006: von Meyenn Ferdinand; Schaefer Martin; Weighardt Heike; Bauer Stefan; Kirschning Carsten J; Wagner Hermann; Sparwasser Tim
Toll-like receptor 9 contributes to recognition of Mycobacterium bovis Bacillus Calmette-Guérin by Flt3-ligand generated dendritic cells.
Immunobiology 2006;211(6-8):557-65.
2005: Baratin Myriam; Roetynck Sophie; Lépolard Catherine; Falk Christine; Sawadogo Serge; Uematsu Satoshi; Akira Shizuo; Ryffel Bernhard; Tiraby Jean-Gérard; Alexopoulou Lena; Kirschning Carsten J; Gysin Jürg; Vivier Eric; Ugolini Sophie
Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14747-52.
2005: Leemans Jaklien C; Stokman Geurt; Claessen Nike; Rouschop Kasper M; Teske Gwendoline J D; Kirschning Carsten J; Akira Shizuo; van der Poll Tom; Weening Jan J; Florquin Sandrine
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney.
The Journal of clinical investigation 2005;115(10):2894-903.
2005: Straub Rainer H; Pongratz Georg; Weidler Claudia; Linde Hans-Jörg; Kirschning Carsten J; Glück Thomas; Schölmerich Jürgen; Falk Werner
Ablation of the sympathetic nervous system decreases gram-negative and increases gram-positive bacterial dissemination: key roles for tumor necrosis factor/phagocytes and interleukin-4/lymphocytes.
The Journal of infectious diseases 2005;192(4):560-72.
2005: Mu H-H; Pennock N D; Humphreys J; Kirschning C J; Cole B C
Engagement of Toll-like receptors by mycoplasmal superantigen: downregulation of TLR2 by MAM/TLR4 interaction.
Cellular microbiology 2005;7(6):789-97.
2005: Borsutzky Stefan; Kretschmer Karsten; Becker Pablo D; Mühlradt Peter F; Kirschning Carsten J; Weiss Siegfried; Guzmán Carlos A
The mucosal adjuvant macrophage-activating lipopeptide-2 directly stimulates B lymphocytes via the TLR2 without the need of accessory cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(10):6308-13.
2005: Yasuda Kei; Yu Philipp; Kirschning Carsten J; Schlatter Beatrix; Schmitz Frank; Heit Antje; Bauer Stefan; Hochrein Hubertus; Wagner Hermann
Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(10):6129-36.
2005: Meng Guangxun; Grabiec Alina; Rutz Mark; Metzger Jochen; Luppa Peter B; Wagner Hermann; Bauer Stefan; Kirschning Carsten J
Murine TLR2 expression analysis and systemic antagonism by usage of specific monoclonal antibodies.
Immunology letters 2005;98(2):200-7.
2005: Wang Xiaohui; Ma Ying; Weis John H; Zachary James F; Kirschning Carsten J; Weis Janis J
Relative contributions of innate and acquired host responses to bacterial control and arthritis development in Lyme disease.
Infection and immunity 2005;73(1):657-60.
2004: Roeder Alexander; Kirschning Carsten J; Rupec Rudolf A; Schaller Martin; Weindl Günther; Korting Hans Christian
Toll-like receptors as key mediators in innate antifungal immunity.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2004;42(6):485-98.
2004: Grabiec Alina; Meng Guangxun; Fichte Sylvia; Bessler Wolfgang; Wagner Hermann; Kirschning Carsten J
Human but not murine toll-like receptor 2 discriminates between tri-palmitoylated and tri-lauroylated peptides.
The Journal of biological chemistry 2004;279(46):48004-12.
2004: Da Costa Clarissa U Prazeres; Wantia Nina; Kirschning Carsten J; Busch Dirk H; Rodriguez Nuria; Wagner Hermann; Miethke Thomas
Heat shock protein 60 from Chlamydia pneumoniae elicits an unusual set of inflammatory responses via Toll-like receptor 2 and 4 in vivo.
European journal of immunology 2004;34(10):2874-84.
2004: Roeder Alexander; Kirschning Carsten J; Schaller Martin; Weindl Gunther; Wagner Hermann; Korting Hans-Christian; Rupec Rudolf A
Induction of nuclear factor- kappa B and c-Jun/activator protein-1 via toll-like receptor 2 in macrophages by antimycotic-treated Candida albicans.
The Journal of infectious diseases 2004;190(7):1318-26.
2004: Müller Silke D C; Müller Markus R; Huber Maria; Esche Uv Ulrich v d; Kirschning Carsten J; Wagner H; Bessler Wolfgang G; Mittenbühler Klaus
Triacyl-lipopentapeptide adjuvants: TLR2-dependent activation of macrophages and modulation of receptor-mediated cell activation by altering acyl-moieties.
International immunopharmacology 2004;4(10-11):1287-300.
2004: Bolz Devin D; Sundsbak Rhianna S; Ma Ying; Akira Shizuo; Kirschning Carsten J; Zachary James F; Weis John H; Weis Janis J
MyD88 plays a unique role in host defense but not arthritis development in Lyme disease.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):2003-10.
2004: Brattig Norbert W; Bazzocchi Chiara; Kirschning Carsten J; Reiling Norbert; Büttner Dietrich W; Ceciliani Fabrizio; Geisinger Frank; Hochrein Hubertus; Ernst Martin; Wagner Hermann; Bandi Claudio; Hoerauf Achim
The major surface protein of Wolbachia endosymbionts in filarial nematodes elicits immune responses through TLR2 and TLR4.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):437-45.
2004: Gruber Anton; Mancek Mateja; Wagner Hermann; Kirschning Carsten J; Jerala Roman
Structural model of MD-2 and functional role of its basic amino acid clusters involved in cellular lipopolysaccharide recognition.
The Journal of biological chemistry 2004;279(27):28475-82.
2004: Koedel Uwe; Rupprecht Tobias; Angele Barbara; Heesemann Juergen; Wagner Hermann; Pfister Hans-Walter; Kirschning Carsten J
MyD88 is required for mounting a robust host immune response to Streptococcus pneumoniae in the CNS.
Brain : a journal of neurology 2004;127(Pt 6):1437-45.
2004: Meng Guangxun; Rutz Mark; Schiemann Matthias; Metzger Jochen; Grabiec Alina; Schwandner Ralf; Luppa Peter B; Ebel Frank; Busch Dirk H; Bauer Stefan; Wagner Hermann; Kirschning Carsten J
Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes.
The Journal of clinical investigation 2004;113(10):1473-81.
2004: Hallatschek Werner; Fiedler Gesa; Kirschning Carsten J; Creutzburg Fränzi; Lamping Norbert; Nüssler Andreas; Schumann Ralf R
Inhibition of hepatic transcriptional induction of lipopolysaccharide-binding protein by transforming-growth-factor beta 1.
European journal of immunology 2004;34(5):1441-50.
2004: Heil Florian; Hemmi Hiroaki; Hochrein Hubertus; Ampenberger Franziska; Kirschning Carsten; Akira Shizuo; Lipford Grayson; Wagner Hermann; Bauer Stefan
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.
Science (New York, N.Y.) 2004;303(5663):1526-9.
2004: Roeder Alexander; Kirschning Carsten J; Rupec Rudolf A; Schaller Martin; Korting Hans Christian
Toll-like receptors and innate antifungal responses.
Trends in microbiology 2004;12(1):44-9.
2004: Sobek Vera; Birkner Nico; Falk Ingrid; Würch Andreas; Kirschning Carsten J; Wagner Hermann; Wallich Reinhard; Lamers Marinus C; Simon Markus M
Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease.
Arthritis research & therapy 2004;6(5):R433-46.
2003: Sing Andreas; Tvardovskaia Natalia; Rost Dagmar; Kirschning Carsten J; Wagner Hermann; Heesemann Jürgen
Contribution of toll-like receptors 2 and 4 in an oral Yersinia enterocolitica mouse infection model.
International journal of medical microbiology : IJMM 2003;293(5):341-8.
2003: Haase Rudolf; Kirschning Carsten J; Sing Andreas; Schröttner Percy; Fukase Koichi; Kusumoto Shoichi; Wagner Hermann; Heesemann Jürgen; Ruckdeschel Klaus
A dominant role of Toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(8):4294-303.
2003: Lembo Annalisa; Kalis Christoph; Kirschning Carsten J; Mitolo Vincenzo; Jirillo Emilio; Wagner Hermann; Galanos Chris; Freudenberg Marina A
Differential contribution of Toll-like receptors 4 and 2 to the cytokine response to Salmonella enterica serovar Typhimurium and Staphylococcus aureus in mice.
Infection and immunity 2003;71(10):6058-62.
2003: Meng Guangxun; Grabiec Alina; Vallon Mario; Ebe Barbara; Hampel Sabrina; Bessler Wolfgang; Wagner Hermann; Kirschning Carsten J
Cellular recognition of tri-/di-palmitoylated peptides is independent from a domain encompassing the N-terminal seven leucine-rich repeat (LRR)/LRR-like motifs of TLR2.
The Journal of biological chemistry 2003;278(41):39822-9.
2003: Meier A; Kirschning C J; Nikolaus T; Wagner H; Heesemann J; Ebel F
Toll-like receptor (TLR) 2 and TLR4 are essential for Aspergillus-induced activation of murine macrophages.
Cellular microbiology 2003;5(8):561-70.
2003: Diterich Isabel; Rauter Carolin; Kirschning Carsten J; Hartung Thomas
Borrelia burgdorferi-induced tolerance as a model of persistence via immunosuppression.
Infection and immunity 2003;71(7):3979-87.
2003: Yoder Alyson; Wang Xiaohui; Ma Ying; Philipp Mario T; Heilbrun Marta; Weis John H; Kirschning Carsten J; Wooten R Mark; Weis Janis J
Tripalmitoyl-S-glyceryl-cysteine-dependent OspA vaccination of toll-like receptor 2-deficient mice results in effective protection from Borrelia burgdorferi challenge.
Infection and immunity 2003;71(7):3894-900.
2003: Prebeck Sigrid; Brade Helmut; Kirschning Carsten J; da Costa Clarissa Prazeres; Dürr Susanne; Wagner Hermann; Miethke Thomas
The Gram-negative bacterium Chlamydia trachomatis L2 stimulates tumor necrosis factor secretion by innate immune cells independently of its endotoxin.
Microbes and infection / Institut Pasteur 2003;5(6):463-70.
2003: Koedel Uwe; Angele Barbara; Rupprecht Tobias; Wagner Hermann; Roggenkamp Andreas; Pfister Hans-Walter; Kirschning Carsten J
Toll-like receptor 2 participates in mediation of immune response in experimental pneumococcal meningitis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(1):438-44.
2003: Sing Andreas; Rost Dagmar; Tvardovskaia Natalia; Roggenkamp Andreas; Geiger Anna M; Kirschning Carsten J; Wiedemann Agnès; Aepfelbacher Martin; Heesemann Jürgen
Mechanisms of Yersinia enterocolitica evasion of the host innate immune response by V antigen.
Advances in experimental medicine and biology 2003;529():165-7.
2002: Sing Andreas; Rost Dagmar; Tvardovskaia Natalia; Roggenkamp Andreas; Wiedemann Agnès; Kirschning Carsten J; Aepfelbacher Martin; Heesemann Jürgen
Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression.
The Journal of experimental medicine 2002;196(8):1017-24.
2002: Reiling Norbert; Hölscher Christoph; Fehrenbach Alexandra; Kröger Svenja; Kirschning Carsten J; Goyert Sanna; Ehlers Stefan
Cutting edge: Toll-like receptor (TLR)2- and TLR4-mediated pathogen recognition in resistance to airborne infection with Mycobacterium tuberculosis.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(7):3480-4.
2002: Weighardt Heike; Kaiser-Moore Simone; Vabulas Ramunas M; Kirschning Carsten J; Wagner Hermann; Holzmann Bernhard
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):2823-7.
2002: Costa Clarissa Prazeres da; Kirschning Carsten J; Busch Dirk; Dürr Susanne; Jennen Luise; Heinzmann Ulrich; Prebeck Sigrid; Wagner Hermann; Miethke Thomas
Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniae.
European journal of immunology 2002;32(9):2460-70.
2002: Bieback Karen; Lien Egil; Klagge Ingo M; Avota Elita; Schneider-Schaulies Jürgen; Duprex W Paul; Wagner Herrmann; Kirschning Carsten J; Ter Meulen Volker; Schneider-Schaulies Sibylle
Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling.
Journal of virology 2002;76(17):8729-36.
2002: Vabulas Ramunas M; Braedel Sibylla; Hilf Norbert; Singh-Jasuja Harpreet; Herter Sylvia; Ahmad-Nejad Parviz; Kirschning Carsten J; Da Costa Clarissa; Rammensee Hans-Georg; Wagner Hermann; Schild Hansjorg
The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway.
The Journal of biological chemistry 2002;277(23):20847-53.
2002: Vabulas Ramunas M; Ahmad-Nejad Parviz; Ghose Sanghamitra; Kirschning Carsten J; Issels Rolf D; Wagner Hermann
HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway.
The Journal of biological chemistry 2002;277(17):15107-12.
2002: Wooten R Mark; Ma Ying; Yoder R Alyson; Brown Jeanette P; Weis John H; Zachary James F; Kirschning Carsten J; Weis Janis J
Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):348-55.
2002: Wooten R Mark; Ma Ying; Yoder R Alyson; Brown Jeanette P; Weis John H; Zachary James F; Kirschning Carsten J; Weis Janis J
Toll-like receptor 2 plays a pivotal role in host defense and inflammatory response to Borrelia burgdorferi.
Vector borne and zoonotic diseases (Larchmont, N.Y.) 2002;2(4):275-8.
2002: Kirschning C J; Schumann R R
TLR2: cellular sensor for microbial and endogenous molecular patterns.
Current topics in microbiology and immunology 2002;270():121-44.
2001: Kirschning C J; Bauer S
Toll-like receptors: cellular signal transducers for exogenous molecular patterns causing immune responses.
International journal of medical microbiology : IJMM 2001;291(4):251-60.
2001: Prebeck S; Kirschning C; Dürr S; da Costa C; Donath B; Brand K; Redecke V; Wagner H; Miethke T
Predominant role of toll-like receptor 2 versus 4 in Chlamydia pneumoniae-induced activation of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(6):3316-23.
2001: Vabulas R M; Ahmad-Nejad P; da Costa C; Miethke T; Kirschning C J; Häcker H; Wagner H
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells.
The Journal of biological chemistry 2001;276(33):31332-9.
2001: Bauer S; Kirschning C J; Häcker H; Redecke V; Hausmann S; Akira S; Wagner H; Lipford G B
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(16):9237-42.
2001: Michelsen K S; Aicher A; Mohaupt M; Hartung T; Dimmeler S; Kirschning C J; Schumann R R
The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2.
The Journal of biological chemistry 2001;276(28):25680-6.
2001: Opitz B; Schröder N W; Spreitzer I; Michelsen K S; Kirschning C J; Hallatschek W; Zähringer U; Hartung T; Göbel U B; Schumann R R
Toll-like receptor-2 mediates Treponema glycolipid and lipoteichoic acid-induced NF-kappaB translocation.
The Journal of biological chemistry 2001;276(25):22041-7.
2001: Werts C; Tapping R I; Mathison J C; Chuang T H; Kravchenko V; Saint Girons I; Haake D A; Godowski P J; Hayashi F; Ozinsky A; Underhill D M; Kirschning C J; Wagner H; Aderem A; Tobias P S; Ulevitch R J
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.
Nature immunology 2001;2(4):346-52.
2001: Wang Q; Dziarski R; Kirschning C J; Muzio M; Gupta D
Micrococci and peptidoglycan activate TLR2-->MyD88-->IRAK-->TRAF-->NIK-->IKK-->NF-kappaB signal transduction pathway that induces transcription of interleukin-8.
Infection and immunity 2001;69(4):2270-6.
2001: Dziarski R; Wang Q; Miyake K; Kirschning C J; Gupta D
MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to Gram-positive and Gram-negative bacteria and their cell wall components.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1938-44.
2000: Faure E; Equils O; Sieling P A; Thomas L; Zhang F X; Kirschning C J; Polentarutti N; Muzio M; Arditi M
Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells.
The Journal of biological chemistry 2000;275(15):11058-63.
1999: Hirschfeld M; Kirschning C J; Schwandner R; Wesche H; Weis J H; Wooten R M; Weis J J
Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(5):2382-6.
1999: Wesche H; Gao X; Li X; Kirschning C J; Stark G R; Cao Z
IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family.
The Journal of biological chemistry 1999;274(27):19403-10.
1999: Schwandner R; Dziarski R; Wesche H; Rothe M; Kirschning C J
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2.
The Journal of biological chemistry 1999;274(25):17406-9.
1999: Zhang F X; Kirschning C J; Mancinelli R; Xu X P; Jin Y; Faure E; Mantovani A; Rothe M; Muzio M; Arditi M
Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.
The Journal of biological chemistry 1999;274(12):7611-4.
1998: Kirschning C J; Wesche H; Merrill Ayres T; Rothe M
Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide.
The Journal of experimental medicine 1998;188(11):2091-7.
1998: Schumann R R; Pfeil D; Freyer D; Buerger W; Lamping N; Kirschning C J; Goebel U B; Weber J R
Lipopolysaccharide and pneumococcal cell wall components activate the mitogen activated protein kinases (MAPK) erk-1, erk-2, and p38 in astrocytes.
Glia 1998;22(3):295-305.
1998: Schumann R R; Belka C; Reuter D; Lamping N; Kirschning C J; Weber J R; Pfeil D
Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells.
Blood 1998;91(2):577-84.
1997: Kirschning C J; Unbehaun A; Fiedler G; Hallatschek W; Lamping N; Pfeil D; Schumann R R
The transcriptional activation pattern of lipopolysaccharide binding protein (LBP) involving transcription factors AP-1 and C/EBP beta.
Immunobiology 1997;198(1-3):124-35.
1997: Kirschning C J; Au-Young J; Lamping N; Reuter D; Pfeil D; Seilhamer J J; Schumann R R
Similar organization of the lipopolysaccharide-binding protein (LBP) and phospholipid transfer protein (PLTP) genes suggests a common gene family of lipid-binding proteins.
Genomics 1997;46(3):416-25.
1997: Song H Y; Régnier C H; Kirschning C J; Goeddel D V; Rothe M
Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9792-6.
1997: Kirschning C; Unbehaun A; Lamping N; Pfeil D; Herrmann F; Schumann R R
Control of transcriptional activation of the lipopolysaccharide binding protein (LBP) gene by proinflammatory cytokines.
Cytokines, cellular & molecular therapy 1997;3(1):59-62.
1996: Lamping N; Hoess A; Yu B; Park T C; Kirschning C J; Pfeil D; Reuter D; Wright S D; Herrmann F; Schumann R R
Effects of site-directed mutagenesis of basic residues (Arg 94, Lys 95, Lys 99) of lipopolysaccharide (LPS)-binding protein on binding and transfer of LPS and subsequent immune cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(10):4648-56.
1996: Schumann R R; Kirschning C J; Unbehaun A; Aberle H P; Knope H P; Lamping N; Ulevitch R J; Herrmann F
The lipopolysaccharide-binding protein is a secretory class 1 acute-phase protein whose gene is transcriptionally activated by APRF/STAT/3 and other cytokine-inducible nuclear proteins.
Molecular and cellular biology 1996;16(7):3490-503.
1996: Schumann R R; Pfeil D; Lamping N; Kirschning C; Scherzinger G; Schlag P; Karawajew L; Herrmann F
Lipopolysaccharide induces the rapid tyrosine phosphorylation of the mitogen-activated protein kinases erk-1 and p38 in cultured human vascular endothelial cells requiring the presence of soluble CD14.
Blood 1996;87(7):2805-14.
1996: Schumann R R; Nakarai T; Gruss H J; Brach M A; von Arnim U; Kirschning C; Karawajew L; Ludwig W D; Renauld J C; Ritz J; Herrmann F
Transcript synthesis and surface expression of the interleukin-2 receptor (alpha-, beta-, and gamma-chain) by normal and malignant myeloid cells.
Blood 1996;87(6):2419-27.
1994: Kiehntopf M; Brach M A; Licht T; Petschauer S; Karawajew L; Kirschning C; Herrmann F
Ribozyme-mediated cleavage of the MDR-1 transcript restores chemosensitivity in previously resistant cancer cells.
The EMBO journal 1994;13(19):4645-52.
1994: Schumann R R; Lamping N; Kirschning C; Knopf H P; Hoess A; Herrmann F
Lipopolysaccharide binding protein: its role and therapeutical potential in inflammation and sepsis.
Biochemical Society transactions 1994;22(1):80-2.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Carsten Kirschning

Research Profile (preview)

Chemicals & Drugs

Living Beings

Physiology

Anatomy

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Carsten Kirschning (preview)

All Publications