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Makoto Kiso

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Genes & Molecular Sequences

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Lewis Blood-Group System

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Yoshihisa Yamada; Takuma Aoyama; Hisayoshi Fujiwara; Takako Fujiwara; Masamitsu Iwasa; Makoto Kiso; Hiroyuki Kobayashi; Kazuhiko Nishigaki; Shohei Sumi; Genzou Takemura; Hiroaki Ushikoshi; Shinya Minatoguchi
Postinfarct active cardiac-targeted delivery of erythropoietin by liposomes with sialyl Lewis X repairs infarcted myocardium in rabbits.
Shinya Nakashima; Risa Saito; Hideki Tamai; Hiromune Ando; Hideharu Ishida; Makoto Kiso
Efficiently synthesizing lacto-ganglio-series gangliosides by using a glucosyl ceramide cassette approach: the total synthesis of ganglioside X2.
Tomohiro Nohara; Takashi Suzuki; Maho Yamaguchi; Tatsuya Komori; Hiromune Ando; Kazuya I P J Hidari; Akihiro Imamura; Hideharu Ishida; Makoto Kiso
Design and synthesis of a novel ganglioside ligand for influenza A viruses.

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All Publications

2013: Yoshihisa Yamada; Takuma Aoyama; Hisayoshi Fujiwara; Takako Fujiwara; Masamitsu Iwasa; Makoto Kiso; Hiroyuki Kobayashi; Kazuhiko Nishigaki; Shohei Sumi; Genzou Takemura; Hiroaki Ushikoshi; Shinya Minatoguchi
Postinfarct active cardiac-targeted delivery of erythropoietin by liposomes with sialyl Lewis X repairs infarcted myocardium in rabbits.
American journal of physiology. Heart and circulatory physiology 2013;304(8):H1124-33.
2012: Shinya Nakashima; Risa Saito; Hideki Tamai; Hiromune Ando; Hideharu Ishida; Makoto Kiso
Efficiently synthesizing lacto-ganglio-series gangliosides by using a glucosyl ceramide cassette approach: the total synthesis of ganglioside X2.
Chemistry, an Asian journal 2012;7(5):1041-51.
2012: Tomohiro Nohara; Takashi Suzuki; Maho Yamaguchi; Tatsuya Komori; Hiromune Ando; Kazuya I P J Hidari; Akihiro Imamura; Hideharu Ishida; Makoto Kiso
Design and synthesis of a novel ganglioside ligand for influenza A viruses.
Molecules (Basel, Switzerland) 2012;17(8):9590-620.
2011: Yuki Iwayama; Hiromune Ando; Hideharu Ishida; Hide-Nori Tanaka; Makoto Kiso
Synthesis of the glycan moiety of ganglioside HPG-7 with an unusual trimer of sialic acid as the inner sugar residue.
Chemical communications (Cambridge, England) 2011;47(34):9726-8.
2011: Kohki Fujikawa; Shinya Nakashima; Miku Konishi; Tomoaki Fuse; Naoko Komura; Takayuki Ando; Hiromune Ando; Nobuhiro Yuki; Hideharu Ishida; Makoto Kiso
The first total synthesis of ganglioside GalNAc-GD1a, a target molecule for autoantibodies in Guillain-Barré syndrome.
Chemistry (Weinheim an der Bergstrasse, Germany) 2011;17(20):5641-51.
2011: Hajjaj H M Abdu-Allah; Kozo Watanabe; Gladys C Completo; Magesh Sadagopan; Koji Hayashizaki; Chiaki Takaku; Taichi Tamanaka; Hiromu Takematsu; Yasunori Kozutsumi; James C Paulson; Takeshi Tsubata; Hiromune Ando; Hideharu Ishida; Makoto Kiso
CD22-antagonists with nanomolar potency: the synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold.
Bioorganic & medicinal chemistry 2011;19(6):1966-71.
2011: Hideki Tamai; Hiromune Ando; Hide-Nori Tanaka; Ritsuko Hosoda-Yabe; Tomio Yabe; Hideharu Ishida; Makoto Kiso
The total synthesis of the neurogenic ganglioside LLG-3 isolated from the starfish Linckia laevigata.
Angewandte Chemie (International ed. in English) 2011;50(10):2330-3.
2011: Shinya Nakashima; Hiromune Ando; Akihiro Imamura; Nobuhiro Yuki; Hideharu Ishida; Makoto Kiso
A first total synthesis of a hybrid-type ganglioside associated with amyotrophic lateral sclerosis-like disorder.
Chemistry (Weinheim an der Bergstrasse, Germany) 2011;17(2):588-97.
2011: Hiroyo Shimizu; Hiromune Ando; Akihiro Imamura; Hideharu Ishida; Yuki Iwayama; Makoto Kiso
Synthesis of the disialic acid-embedded glycan part of ganglioside HPG-1.
Bioscience, biotechnology, and biochemistry 2011;75(10):2079-82.
2010: Hiromune Ando; Hideharu Ishida; Makoto Kiso
Renewed synthetic approach to gangliosides exploiting versatile and powerful synthetic units.
Methods in enzymology 2010;478():521-40.
2009: Hajjaj H M Abdu-Allah; Kozo Watanabe; Koji Hayashizaki; Chiaki Takaku; Taichi Tamanaka; Hiromu Takematsu; Yasunori Kozutsumi; Takeshi Tsubata; Hideharu Ishida; Makoto Kiso
Potent small molecule mouse CD22-inhibitors: exploring the interaction of the residue at C-2 of sialic acid scaffold.
Bioorganic & medicinal chemistry letters 2009;19(19):5573-5.
2009: Tatsuya Komori; Akihiro Imamura; Hiromune Ando; Hideharu Ishida; Makoto Kiso
Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates.
Carbohydrate research 2009;344(12):1453-63.
2009: Sadagopan Magesh; Vats Savita; Setsuko Moriya; Tohru Suzuki; Taeko Miyagi; Hideharu Ishida; Makoto Kiso
Human sialidase inhibitors: design, synthesis, and biological evaluation of 4-acetamido-5-acylamido-2-fluoro benzoic acids.
Bioorganic & medicinal chemistry 2009;17(13):4595-603.
2009: Akihiro Imamura; Hiromune Ando; Hideharu Ishida; Makoto Kiso
Ganglioside GQ1b: efficient total synthesis and the expansion to synthetic derivatives to elucidate its biological roles.
The Journal of organic chemistry 2009;74(8):3009-23.
2009: Yuki Iwayama; Hiromune Ando; Hideharu Ishida; Makoto Kiso
A first total synthesis of ganglioside HLG-2.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(18):4637-48.
2009: Tetsuro Sato; Akihiro Imamura; Hiromune Ando; Hideharu Ishida; Makoto Kiso
Di-tert-butylsilylene-directed alpha-selective synthesis of p-nitrophenyl T-antigen analogues.
Glycoconjugate journal 2009;26(1):83-98.
2008: Hajjaj H M Abdu-Allah; Taichi Tamanaka; Jie Yu; Lu Zhuoyuan; Magesh Sadagopan; Takahiro Adachi; Takeshi Tsubata; Soerge Kelm; Hideharu Ishida; Makoto Kiso
Design, synthesis, and structure-affinity relationships of novel series of sialosides as CD22-specific inhibitors.
Journal of medicinal chemistry 2008;51(21):6665-81.
2008: Kohki Fujikawa; Akihiro Imamura; Hideharu Ishida; Makoto Kiso
Synthesis of a GM3 ganglioside analogue carrying a phytoceramide moiety by intramolecular glycosylation as a key step.
Carbohydrate research 2008;343(16):2729-34.
2008: Tatsuya Komori; Takayuki Ando; Akihiro Imamura; Yu-Teh Li; Hideharu Ishida; Makoto Kiso
Design and efficient synthesis of novel GM2 analogues with respect to the elucidation of the function of GM2 activator.
Glycoconjugate journal 2008;25(7):647-61.
2008: Takeru Yoshikawa; Yuki Kato; Nobuhiro Yuki; Tomio Yabe; Hideharu Ishida; Makoto Kiso
A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.
Glycoconjugate journal 2008;25(6):545-53.
2008: Masanori Yamaguchi; Hideharu Ishida; Makoto Kiso
Total synthesis of 6-O-sulfo-sialylparagloboside: a widely useful glycoprobe for biochemical research.
Carbohydrate research 2008;343(10-11):1849-57.
2008: Akihiro Imamura; Takeru Yoshikawa; Tatsuya Komori; Masatoshi Ando; Hiromune Ando; Masahiro Wakao; Yasuo Suda; Hideharu Ishida; Makoto Kiso
Design and synthesis of versatile ganglioside probes for carbohydrate microarrays.
Glycoconjugate journal 2008;25(3):269-78.
2008: Sadagopan Magesh; Setsuko Moriya; Tohru Suzuki; Taeko Miyagi; Hideharu Ishida; Makoto Kiso
Design, synthesis, and biological evaluation of human sialidase inhibitors. Part 1: selective inhibitors of lysosomal sialidase (NEU1).
Bioorganic & medicinal chemistry letters 2008;18(2):532-7.
2007: Toshihiko Sawada; Tomohiro Hashimoto; Hirofumi Nakano; Tohru Suzuki; Yasuo Suzuki; Yoshihiro Kawaoka; Hideharu Ishida; Makoto Kiso
Influenza viral hemagglutinin complicated shape is advantageous to its binding affinity for sialosaccharide receptor.
Biochemical and biophysical research communications 2007;355(1):6-9.
2006: Toshihiko Sawada; Tomohiro Hashimoto; Hirofumi Nakano; Tohru Suzuki; Hideharu Ishida; Makoto Kiso
Why does avian influenza A virus hemagglutinin bind to avian receptor stronger than to human receptor? Ab initio fragment molecular orbital studies.
Biochemical and biophysical research communications 2006;351(1):40-3.
2006: Akihiro Imamura; Akiyoshi Kimura; Hiromune Ando; Hideharu Ishida; Makoto Kiso
Extended applications of di-tert-butylsilylene-directed alpha-predominant galactosylation compatible with C2-participating groups toward the assembly of various glycosides.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(34):8862-70.
2006: Hironao Takaku; Junhei Sato; Hide-Ki Ishida; Toshiyuki Inazu; Hideharu Ishida; Makoto Kiso
A chemical synthesis of UDP-LacNAc and its regioisomer for finding 'oligosaccharide transferases'.
Glycoconjugate journal 2006;23(7-8):565-73.
2006: Sadagopan Magesh; Tohru Suzuki; Taeko Miyagi; Hideharu Ishida; Makoto Kiso
Homology modeling of human sialidase enzymes NEU1, NEU3 and NEU4 based on the crystal structure of NEU2: hints for the design of selective NEU3 inhibitors.
Journal of molecular graphics & modelling 2006;25(2):196-207.
2006: Hiromune Ando; Hiroyo Shimizu; Yukari Katano; Yusuke Koike; Sachiko Koizumi; Hideharu Ishida; Makoto Kiso
Studies on the alpha-(1-->4)- and alpha-(1-->8)-fucosylation of sialic acid for the total assembly of the glycan portions of complex HPG-series gangliosides.
Carbohydrate research 2006;341(10):1522-32.
2006: Tomoaki Fuse; Hiromune Ando; Akihiro Imamura; Naoki Sawada; Hideharu Ishida; Makoto Kiso; Takayuki Ando; Su-Chen Li; Yu-Teh Li
Synthesis and enzymatic susceptibility of a series of novel GM2 analogs.
Glycoconjugate journal 2006;23(5-6):329-43.
2006: María Asunción Campanero-Rhodes; Robert A Childs; Makoto Kiso; Shiro Komba; Christine Le Narvor; Joanna Warren; Diana Otto; Paul R Crocker; Ten Feizi
Carbohydrate microarrays reveal sulphation as a modulator of siglec binding.
Biochemical and biophysical research communications 2006;344(4):1141-6.
2005: Hiromune Ando; Yusuke Koike; Sachiko Koizumi; Hideharu Ishida; Makoto Kiso
1,5-Lactamized sialyl acceptors for various disialoside syntheses: novel method for the synthesis of glycan portions of Hp-s6 and HLG-2 gangliosides.
Angewandte Chemie (International ed. in English) 2005;44(41):6759-63.
2005: Akihiro Imamura; Hiromune Ando; Hideharu Ishida; Makoto Kiso
Di-tert-butylsilylene-directed alpha-selective synthesis of 4-methylumbelliferyl T-antigen.
Organic letters 2005;7(20):4415-8.
2005: Masanori Yamaguchi; Hideharu Ishida; Akiko Kanamori; Reiji Kannagi; Makoto Kiso
6-O-sulfo sialylparagloboside and sialyl Lewis X neo-glycolipids containing lactamized neuraminic acid: synthesis and antigenic reactivity against G159 monoclonal antibody.
Glycoconjugate journal 2005;22(3):95-108.
2004: Christine Galustian; Chae Gyu Park; Wengang Chai; Makoto Kiso; Sandra A Bruening; Young-Sun Kang; Ralph M Steinman; Ten Feizi
High and low affinity carbohydrate ligands revealed for murine SIGN-R1 by carbohydrate array and cell binding approaches, and differing specificities for SIGN-R3 and langerin.
International immunology 2004;16(6):853-66.
2003: Masanori Yamaguchi; Hideharu Ishida; Akiko Kanamori; Reiji Kannagi; Makoto Kiso
Studies on the endogenous L-selectin ligands: systematic and highly efficient total synthetic routes to lactamized-sialyl 6-O-sulfo Lewis X and other novel gangliosides containing lactamized neuraminic acid.
Carbohydrate research 2003;338(24):2793-812.
2003: Hiromi Ito; Hideharu Ishida; Brian E Collins; Susan E Fromholt; Ronald Schnaar; Makoto Kiso
Systematic synthesis and MAG-binding activity of novel sulfated GM1b analogues as mimics of Chol-1 (alpha-series) gangliosides: highly active ligands for neural siglecs.
Carbohydrate research 2003;338(16):1621-39.
2003: Takayuki Ando; Hideharu Ishida; Makoto Kiso
First total synthesis of alpha-(2-->3)/alpha-(2-->6)-disialyl lactotetraosyl ceramide and disialyl Lewis A ganglioside as cancer-associated carbohydrate antigens.
Carbohydrate research 2003;338(6):503-14.
2002: Masanori Yamaguchi; Hideharu Ishida; Christine Galustian; Ten Feizi; Makoto Kiso
Synthesis and selectin-binding activity of N-deacetylsialyl Lewis X ganglioside.
Carbohydrate research 2002;337(21-23):2111-7.
2002: Tatsuki Komori; Saori Kondo; Hironume Ando; Hideharu Ishida; Makoto Kiso
A first total synthesis of a novel sulfated ganglioside, 3'-O-sulfo-GM1b.
Carbohydrate research 2002;337(18):1679-86.
2002: Shou Takashima; Hide-Ki Ishida; Toshiyuki Inazu; Takayuki Ando; Hideharu Ishida; Makoto Kiso; Shuichi Tsuji; Masafumi Tsujimoto
Molecular cloning and expression of a sixth type of alpha 2,8-sialyltransferase (ST8Sia VI) that sialylates O-glycans.
The Journal of biological chemistry 2002;277(27):24030-8.
2002: Ronald Schnaar; Susan E Fromholt; Yanping Gong; Alka A Vyas; Wouter Laroy; Dawn M Wayman; Marija Heffer-Lauc; Hiromi Ito; Hideharu Ishida; Makoto Kiso; John W Griffin; Kazim A Shiekh
Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides.
Analytical biochemistry 2002;302(2):276-84.
2002: Christine Galustian; Robert A Childs; Mark Stoll; Hideharu Ishida; Makoto Kiso; Ten Feizi
Synergistic interactions of the two classes of ligand, sialyl-Lewis(a/x) fuco-oligosaccharides and short sulpho-motifs, with the P- and L-selectins: implications for therapeutic inhibitor designs.
Immunology 2002;105(3):350-9.
2001: D Mamelak; Murugesapillai Mylvaganam; E Tanahashi; H Ito; Hideharu Ishida; Makoto Kiso; Clifford A Lingwood
The aglycone of sulfogalactolipids can alter the sulfate ester substitution position required for hsc70 recognition.
Carbohydrate research 2001;335(2):91-100.
2001: S Komba; Masanori Yamaguchi; Hideharu Ishida; Makoto Kiso
6-O-sulfo de-N-acetylsialyl Lewis X as a novel high-affinity ligand for human L-selectin: total synthesis and structural characterization.
Biological chemistry 2001;382(2):233-40.
2001: N Otsubo; Hideharu Ishida; Makoto Kiso
Synthesis of novel ganglioside GM4 analogues containing N-deacetylated and lactamized sialic acid: probes for searching new ligand structures for human L-selectin.
Carbohydrate research 2001;330(1):1-5.
2000: K Fukunaga; K Shinoda; Hideharu Ishida; Makoto Kiso
Systematic synthesis of sulfated sialyl-alpha-(2 --> 3)-neolactotetraose derivatives and their acceptor specificity for an alpha-(1 --> 3)-fucosyltransferase (Fuc-TVII) involved in the biosynthesis of L-selectin ligand.
Carbohydrate research 2000;328(2):85-94.
1999: Brian E Collins; Hiromi Ito; N Sawada; Hideharu Ishida; Makoto Kiso; Ronald Schnaar
Enhanced binding of the neural siglecs, myelin-associated glycoprotein and Schwann cell myelin protein, to Chol-1 (alpha-series) gangliosides and novel sulfated Chol-1 analogs.
The Journal of biological chemistry 1999;274(53):37637-43.
1999: Hiromi Ito; Hideharu Ishida; H Waki; S Ando; Makoto Kiso
Total synthesis of a cholinergic neuron-specific ganglioside GT1a alpha: a high affinity ligand for myelin-associated glycoprotein (MAG).
Glycoconjugate journal 1999;16(10):585-98.
1999: Christine Galustian; André Lubineau; Christine Le Narvor; Makoto Kiso; G Brown; Ten Feizi
L-selectin interactions with novel mono- and multisulfated Lewisx sequences in comparison with the potent ligand 3'-sulfated Lewisa.
The Journal of biological chemistry 1999;274(26):18213-7.
1999: N Sawada; Hideharu Ishida; Brian E Collins; Ronald Schnaar; Makoto Kiso
Ganglioside GD1 alpha analogues as high-affinity ligands for myelin-associated glycoprotein (MAG).
Carbohydrate research 1999;316(1-4):1-5.
1999: C Mitsuoka; K Ohmori; N Kimura; Akiko Kanamori; S Komba; Hideharu Ishida; Makoto Kiso; Reiji Kannagi
Regulation of selectin binding activity by cyclization of sialic acid moiety of carbohydrate ligands on human leukocytes.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1597-602.
1998: K Shinoda; E Tanahashi; K Fukunaga; Hideharu Ishida; Makoto Kiso
Detailed acceptor specificities of human alpha1,3-fucosyltransferases, Fuc-TVII and Fuc-TVI.
Glycoconjugate journal 1998;15(10):969-74.
1998: Ronald Schnaar; Brian E Collins; L P Wright; Makoto Kiso; mike tropak; John C Roder; P R Crocker
Myelin-associated glycoprotein binding to gangliosides. Structural specificity and functional implications.
Annals of the New York Academy of Sciences 1998;845():92-105.
1998: K Kumamoto; C Mitsuoka; M Izawa; N Kimura; N Otsubo; Hideharu Ishida; Makoto Kiso; T Yamada; S Hirohashi; Reiji Kannagi
Specific detection of sialyl Lewis X determinant carried on the mucin GlcNAcbeta1-->6GalNAcalpha core structure as a tumor-associated antigen.
Biochemical and biophysical research communications 1998;247(2):514-7.
1998: C Mitsuoka; M Sawada-Kasugai; K Ando-Furui; M Izawa; H Nakanishi; S Nakamura; Hideharu Ishida; Makoto Kiso; Reiji Kannagi
Identification of a major carbohydrate capping group of the L-selectin ligand on high endothelial venules in human lymph nodes as 6-sulfo sialyl Lewis X.
The Journal of biological chemistry 1998;273(18):11225-33.
1998: Hiromi Ito; Hideharu Ishida; Makoto Kiso; A Hasegawa
First total synthesis of ganglioside GT1a alpha.
Carbohydrate research 1998;306(4):581-5.
1998: N Otsubo; Hideharu Ishida; Makoto Kiso; A Hasegawa
Synthesis of sialyl LeX ganglioside analogues modified at C-6 of the galactose residue to elucidate the mechanism of selection recognition.
Carbohydrate research 1998;306(4):517-30.
1997: Hiromi Ito; Hideharu Ishida; Makoto Kiso; A Hasegawa
First total synthesis of ganglioside GT1a alpha.
Carbohydrate research 1997;304(3-4):187-9.
1997: Christine Galustian; Alexander M Lawson; Shiro Komba; Hideharu Ishida; Makoto Kiso; Ten Feizi
Sialyl-Lewis(x) sequence 6-O-sulfated at N-acetylglucosamine rather than at galactose is the preferred ligand for L-selectin and de-N-acetylation of the sialic acid enhances the binding strength.
Biochemical and biophysical research communications 1997;240(3):748-51.
1997: Hideharu Ishida; Y Ito; E Tanahashi; Yu-Teh Li; Makoto Kiso; A Hasegawa
Synthesis of 6'-GM2, a regioisomer of ganglioside GM2, for studying the mechanism of action of GM2 activator.
Carbohydrate research 1997;302(3-4):223-7.
1997: Brian E Collins; Makoto Kiso; A Hasegawa; mike tropak; John C Roder; P R Crocker; Ronald Schnaar
Binding specificities of the sialoadhesin family of I-type lectins. Sialic acid linkage and substructure requirements for binding of myelin-associated glycoprotein, Schwann cell myelin protein, and sialoadhesin.
The Journal of biological chemistry 1997;272(27):16889-95.
1997: H Ando; Hideharu Ishida; Makoto Kiso; A Hasegawa
A synthetic approach to the c-series gangliosides containing sialyl-alpha(2-->8)sialyl-alpha(2-->8)sialic acid: synthesis of ganglioside GT4, alpha(2-->6) GT4 and GT3.
Carbohydrate research 1997;300(3):207-17.
1997: Christine Galustian; Robert A Childs; CT Yuen; A Hasegawa; Makoto Kiso; André Lubineau; G Shaw; Ten Feizi
Valency dependent patterns of binding of human L-selectin toward sialyl and sulfated oligosaccharides of Le(a) and Le(x) types: relevance to anti-adhesion therapeutics.
Biochemistry 1997;36(17):5260-6.
1997: C Mitsuoka; Naoko Kawakami-Kimura; M Kasugai-Sawada; Noriko Hiraiwa; K Toda; Hideharu Ishida; Makoto Kiso; A Hasegawa; Reiji Kannagi
Sulfated sialyl Lewis X, the putative L-selectin ligand, detected on endothelial cells of high endothelial venules by a distinct set of anti-sialyl Lewis X antibodies.
Biochemical and biophysical research communications 1997;230(3):546-51.
1997: Brian E Collins; lynda yang; G Mukhopadhyay; Marie T Filbin; Makoto Kiso; A Hasegawa; Ronald Schnaar
Sialic acid specificity of myelin-associated glycoprotein binding.
The Journal of biological chemistry 1997;272(2):1248-55.
1996: S Komba; Hideharu Ishida; Makoto Kiso; A Hasegawa
Synthesis and biological activities of three sulfated sialyl Le(x) ganglioside analogues for clarifying the real carbohydrate ligand structure of L-selectin.
Bioorganic & medicinal chemistry 1996;4(11):1833-47.
1996: S Komba; Hideharu Ishida; Makoto Kiso; A Hasegawa
Synthesis of sialyl Le(x) ganglioside analogues sulfated at C-6 of either the galactose or N-acetylglucosamine residues, and at both of the galactose and N-acetylglucosamine residues: probes for clarifying the real carbohydrate ligand of L-selectin.
Carbohydrate research 1996;285():C1-8.
1996: Hideharu Ishida; R Miyawaki; Makoto Kiso; A Hasegawa
Systematic synthesis of alpha-sialyl-(2 --> 3)- and -(2 --> 6)-isoglobopentaosylceramides (V3Neu5AciGb5Cer and V6Neu5AciGb5Cer).
Carbohydrate research 1996;284(2):179-90.
1996: S Komba; Hideharu Ishida; Makoto Kiso; A Hasegawa
Synthesis of deoxygalactose-containing sialyl Le(X) ganglioside analogues to elucidate the structure necessary for selectin recognition.
Glycoconjugate journal 1996;13(2):241-54.
1996: lynda yang; C B Zeller; Nancy L Shaper; Makoto Kiso; A Hasegawa; Robert E Shapiro; Ronald Schnaar
Gangliosides are neuronal ligands for myelin-associated glycoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):814-8.
1996: M Yoshida; Hideharu Ishida; Makoto Kiso; A Hasegawa
Synthesis of N-acetyl-4,8-dideoxyneuraminic acid-containing ganglioside GM3.
Carbohydrate research 1996;280(2):331-8.
1995: A Hasegawa; M Kato; T Ando; Hideharu Ishida; Makoto Kiso
Synthesis of sialyl Lewis X ganglioside analogues containing modified L-fucose residues.
Carbohydrate research 1995;274():165-81.
1995: Hideharu Ishida; Y Fujishima; Y Ogawa; Y Kumazawa; Makoto Kiso; A Hasegawa
Synthesis and mitogenic activity of nonreducing-sugar subunit analogs of bacterial lipid A composed only of 3-hydroxytetradecanoic acid and its homologs.
Bioscience, biotechnology, and biochemistry 1995;59(9):1790-2.
1995: Makoto Kiso; K Ando; H Inagaki; Hideharu Ishida; A Hasegawa
Synthetic and structural studies of alpha-sialyl-(2-->6) and alpha-sialyl-(2-->3) 1-deoxynojirimycin derivatives potentially useful for biomedical applications.
Carbohydrate research 1995;272(2):159-78.
1995: A Hasegawa; A Uchimura; Hideharu Ishida; Makoto Kiso
Synthesis of a sialyl Lewis X ganglioside analogue containing N-glycolyl in place of the N-acetyl group in the N-acetylneuraminic acid residue.
Bioscience, biotechnology, and biochemistry 1995;59(6):1091-4.
1994: Makoto Kiso; H Furui; K Ando; Hideharu Ishida; A Hasegawa
Systematic synthesis of N-methyl-1-deoxynojirimycin-containing, Le(x), Le(a), sialyl-Le(x) and sialyl-Le(a) epitopes recognized by selectins.
Bioorganic & medicinal chemistry 1994;2(11):1295-308.
1994: K Ozawa; Y Yamagata; S Satomura; Hideharu Ishida; Makoto Kiso; A Hasegawa
Synthesis of 6(5)- and/or 4(5)-O-glycosyl p-nitrophenyl alpha-maltopentaoside derivatives for the differential assay of human alpha-amylases.
Carbohydrate research 1994;262(1):137-45.
1994: Hideharu Ishida; H Ishida; Makoto Kiso; A Hasegawa
Total synthesis of ganglioside GQ1b.
Carbohydrate research 1994;260(2):C1-6.
1994: T Terada; Makoto Kiso; A Hasegawa
Synthesis of KDN-lactotetraosylceramide, KDN-neolactotetraosylceramide, and KDN-Lewis X ganglioside.
Carbohydrate research 1994;259(2):201-18.
1994: A Hasegawa; T Ando; M Kato; Hideharu Ishida; Makoto Kiso
Synthesis of deoxy-L-fucose-containing sialyl Lewis X ganglioside analogues.
Carbohydrate research 1994;257(1):67-80.
1994: A Hasegawa; T Ando; M Kato; Hideharu Ishida; Makoto Kiso
Synthesis of the methyl thioglycosides of 2-, 3-, and 4-deoxy-L-fucose.
Carbohydrate research 1994;257(1):55-65.
1994: A Kondo; Y Hosokawa; Makoto Kiso; A Hasegawa; I Kato
Analysis of oligosaccharides of human IgG from serum of leukemia patients.
Biochemistry and molecular biology international 1994;32(5):897-902.
1994: CT Yuen; Karel Bezouska; J O'Brien; M Stoll; R Lemoine; André Lubineau; Makoto Kiso; A Hasegawa; N J Bockovich; K C Nicolaou
Sulfated blood group Lewis(a). A superior oligosaccharide ligand for human E-selectin.
The Journal of biological chemistry 1994;269(3):1595-8.
1994: Hideharu Ishida; Y Ohta; Y Tsukada; Y Isogai; H Ishida; Makoto Kiso; A Hasegawa
A facile total synthesis of ganglioside GD2.
Carbohydrate research 1994;252():283-90.
1994: Hideharu Ishida; Makoto Kiso; A Hasegawa
Synthesis of ganglioside analogs containing sulfur in place of oxygen at the linkage positions.
Methods in enzymology 1994;242():183-98.
1994: Makoto Kiso; A Hasegawa
Synthesis of ganglioside GM3 and analogs containing modified sialic acids and ceramides.
Methods in enzymology 1994;242():173-83.
1994: A Hasegawa; Makoto Kiso
Synthesis of sialyl Lewis X ganglioside and analogs.
Methods in enzymology 1994;242():158-73.
1993: Hideharu Ishida; Y Ohta; Y Tsukada; Makoto Kiso; A Hasegawa
A synthetic approach to polysialogangliosides containing alpha-sialyl-(2-->8)-sialic acid: total synthesis of ganglioside GD3.
Carbohydrate research 1993;246():75-88.
1993: K Ozawa; Y Taki; Hideharu Ishida; Y Yamagata; S Satomura; Makoto Kiso; A Hasegawa
Systematic synthesis of sulfur-containing p-nitrophenyl alpha-maltopentaoside derivatives for a differential assay of human alpha-amylases.
Bioscience, biotechnology, and biochemistry 1993;57(5):821-8.
1993: M Yoshida; A Uchimura; Makoto Kiso; A Hasegawa
Synthesis of chemically modified sialic acid-containing sialyl-LeX ganglioside analogues recognized by the selectin family.
Glycoconjugate journal 1993;10(1):3-15.
1992: A Hasegawa; T Nagahama; Makoto Kiso
A facile, systematic synthesis of ganglio-series gangliosides: total synthesis of gangliosides GM1 and GD1a.
Carbohydrate research 1992;235():C13-7.
1992: P J Green; T Tamatani; T Watanabe; M Miyasaka; A Hasegawa; Makoto Kiso; CT Yuen; M S Stoll; Ten Feizi
High affinity binding of the leucocyte adhesion molecule L-selectin to 3'-sulphated-Le(a) and -Le(x) oligosaccharides and the predominance of sulphate in this interaction demonstrated by binding studies with a series of lipid-linked oligosaccharides.
Biochemical and biophysical research communications 1992;188(1):244-51.
1992: H Prabhanjan; K Aoyama; Makoto Kiso; A Hasegawa
Synthesis of disialoganglioside GD1 alpha and its positional isomer.
Carbohydrate research 1992;233():87-99.
1992: A Hasegawa; K Adachi; M Yoshida; Makoto Kiso
Synthesis of a series of ganglioside GM3 analogs containing a deoxy-N-acetylneuraminic acid residue.
Carbohydrate research 1992;230(2):273-88.
1992: A Hasegawa; K Adachi; M Yoshida; Makoto Kiso
Synthesis of the methyl thioglycosides of deoxy-N-acetyl-neuraminic acids for use as glycosyl donors.
Carbohydrate research 1992;230(2):257-72.
1992: A Hasegawa; T Ando; A Kameyama; Makoto Kiso
Stereocontrolled synthesis of sialyl Lewis X ceramide consisting of a pentasaccharide recognized by the selectin family.
Carbohydrate research 1992;230(1):C1-5.
1992: H Furui; Makoto Kiso; A Hasegawa
Synthesis of 1-deoxynojirimycin-containing glycans related to the Lewis X and sialyl-Lewis X epitopes recognized by LEC-CAMs.
Carbohydrate research 1992;229(1):C1-4.
1992: A Hasegawa; M Ogawa; Makoto Kiso
Synthesis of a ganglioside GM3 position isomer, N-acetylneuraminosyl-alpha (2----6)-lactosyl-beta(1----1)-ceramide.
Bioscience, biotechnology, and biochemistry 1992;56(3):535-6.
1992: A Hasegawa; K Adachi; M Yoshida; Makoto Kiso
Synthesis of a ganglioside GM3 analog containing a hydroxymethyl group in place of the carboxyl group in the N-acetylneuraminic acid unit.
Bioscience, biotechnology, and biochemistry 1992;56(3):445-7.
1992: A Hasegawa; H Ogawa; Makoto Kiso
Synthesis of a position isomer of ganglioside GD3 having an alpha-Neu5Ac-(2----9)-alpha-Neu5Ac linkage.
Carbohydrate research 1992;224():185-92.
1992: A Hasegawa; H Ogawa; Hideharu Ishida; Makoto Kiso
Synthesis of an S-(alpha-sialosyl)-(2----9)-O-(alpha-sialosyl)-(2----3')-beta-lactos ylceramide.
Carbohydrate research 1992;224():175-84.
1991: H Prabhanjan; Makoto Kiso; A Hasegawa
Total synthesis of a disialoganglioside GD1 alpha.
Carbohydrate research 1991;222():c1-4.
1991: H Prabhanjan; A Kameyama; Hideharu Ishida; Makoto Kiso; A Hasegawa
Regio- and stereo-selective synthesis of ganglioside GM1b and some positional analogs.
Carbohydrate research 1991;220():127-43.
1991: A Hasegawa; M Morita; Y Kojima; Hideharu Ishida; Makoto Kiso
Synthesis of cerebroside, lactosyl ceramide, and ganglioside GM3 analogs containing beta-thioglycosidically linked ceramide.
Carbohydrate research 1991;214(1):43-53.
1991: A Hasegawa; H Ohki; T Nagahama; Hideharu Ishida; Makoto Kiso
A facile, large-scale preparation of the methyl 2-thioglycoside of N-acetylneuraminic acid, and its usefulness for the alpha-stereoselective synthesis of sialoglycosides.
Carbohydrate research 1991;212():277-81.
1991: H Prabhanjan; Hideharu Ishida; Makoto Kiso; A Hasegawa
A facile total synthesis of ganglioside GM1b and its positional analog.
Carbohydrate research 1991;211(2):C1-5.
1991: A Kameyama; Hideharu Ishida; Makoto Kiso; A Hasegawa
Total synthesis of sialyl Lewis X.
Carbohydrate research 1991;209():c1-c4.
1990: Hideharu Ishida; M Kitagawa; Makoto Kiso; A Hasegawa; I Azuma
Synthesis and immunoadjuvant activity of N-[2-O-(2-acetamido- 1,2,3,5-tetradeoxy-1,5-imino-D-glucitol-3-yl)-D-lactoyl]- L-alanyl-D-isoglutamine.
Carbohydrate research 1990;208():267-72.
1990: A Kameyama; Hideharu Ishida; Makoto Kiso; A Hasegawa
Stereoselective synthesis of sialyl-lactotetraosylceramide and sialylneolactotetraosylceramide.
Carbohydrate research 1990;200():269-85.
1990: Makoto Kiso; M Fujita; Y Ogawa; Hideharu Ishida; A Hasegawa
Synthesis of alpha-Kdo-(2----4)-Kdo disaccharide derivatives and their conjugation with a protected form of GLA-60, a biologically active analog of a lipid A subunit.
Carbohydrate research 1990;196():59-73.
1989: Hideharu Ishida; Y Imai; Makoto Kiso; A Hasegawa; T Sakurai; I Azuma
Synthesis and immunoadjuvant activity of 2,2'-O-[2,2'-diacetamido-2,3,2',3'-tetradeoxy-6,6'-di-O-(2-tetradecyl- hexadecanoyl)-alpha,alpha'-trehalose-3,3'-diyl]bis(N-D-lactoyl-L-alanyl -D-isoglutamine).
Carbohydrate research 1989;195(1):59-66.
1989: T Murase; K P Kartha; Makoto Kiso; A Hasegawa
Synthesis of the alpha-Neu5Ac-(2----6)-Gal structure. Facile 6-O-sialylation following stannylene activation of an unprotected D-galactopyranoside.
Carbohydrate research 1989;195(1):134-7.
1989: Hideharu Ishida; Y Ogawa; Y Imai; Makoto Kiso; A Hasegawa; T Sakurai; I Azuma
Chemical combination of 6-deoxy-6-mycoloylamino-alpha,alpha-trehalose and N-acetyl-6-O-(aminoacyl)muramoyl dipeptide.
Carbohydrate research 1989;194():199-208.
1989: T Murase; Hideharu Ishida; Makoto Kiso; A Hasegawa
A facile, regio- and stereo-selective synthesis of ganglioside GM3.
Carbohydrate research 1989;188():71-80.
1988: T Murase; Hideharu Ishida; Makoto Kiso; A Hasegawa
A facile regio- and stereo-selective synthesis of alpha-glycosides of N-acetylneuraminic acid.
Carbohydrate research 1988;184():c1-4.
1987: Y Fujishima; K Kigawa; Y Ogawa; Makoto Kiso; A Hasegawa; Hideharu Ishida; I Azuma
New synthetic immunomodulators combining a 4-O-phosphono-D-glucosamine derivative related to bacterial lipid A with 1-deoxy-N-acetylmuramoyl dipeptide analogs.
Carbohydrate research 1987;167():317-24.