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Otfried Kistner

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Dose-Response Relationship, Immunologic

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Maikel V W van der Velden; Timo Vesikari; Markus Zeitlinger; Gerald Aichinger; Karima Benamara; Hartmut J Ehrlich; Sandor Fritsch; Otfried Kistner; Herwig Kollaritsch; Alexandra Löw-Baselli; Markus Müller; Eva Maria Pöllabauer; P Noel Barrett
Cell culture (Vero cell) derived whole-virus non-adjuvanted H5N1 influenza vaccine induces long-lasting cross-reactive memory immune response: homologous or heterologous booster response following two dose or single dose priming.
Alexandra Loew-Baselli; Johannes Neugebauer; Borislava G Pavlova; Eva Maria Poellabauer; Rudolf Angermayr; Ulrich Behre; Wolfgang Draxler; Hartmut J Ehrlich; Elisabeth Förster-Waldl; Sandor Fritsch; Karola Kirsten; Otfried Kistner; Ralph Koellges; P Noel Barrett
A non-adjuvanted whole-virus H1N1 pandemic vaccine is well tolerated and highly immunogenic in children and adolescents and induces substantial immunological memory.
Nicolas Sabarth; Helga Savidis-Dacho; Michael G Schwendinger; Otfried Kistner; Thomas R Kreil; Daniel Portsmouth; P Noel Barrett; Peter Brühl; Brian A Crowe; M Keith Howard
A cell culture-derived whole-virus H5N1 vaccine induces long-lasting cross-clade protective immunity in mice which is augmented by a homologous or heterologous booster vaccination.

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All Publications

2012: Maikel V W van der Velden; Timo Vesikari; Markus Zeitlinger; Gerald Aichinger; Karima Benamara; Hartmut J Ehrlich; Sandor Fritsch; Otfried Kistner; Herwig Kollaritsch; Alexandra Löw-Baselli; Markus Müller; Eva Maria Pöllabauer; P Noel Barrett
Cell culture (Vero cell) derived whole-virus non-adjuvanted H5N1 influenza vaccine induces long-lasting cross-reactive memory immune response: homologous or heterologous booster response following two dose or single dose priming.
Vaccine 2012;30(43):6127-35.
2012: Alexandra Loew-Baselli; Johannes Neugebauer; Borislava G Pavlova; Eva Maria Poellabauer; Rudolf Angermayr; Ulrich Behre; Wolfgang Draxler; Hartmut J Ehrlich; Elisabeth Förster-Waldl; Sandor Fritsch; Karola Kirsten; Otfried Kistner; Ralph Koellges; P Noel Barrett
A non-adjuvanted whole-virus H1N1 pandemic vaccine is well tolerated and highly immunogenic in children and adolescents and induces substantial immunological memory.
Vaccine 2012;30(41):5956-66.
2012: Nicolas Sabarth; Helga Savidis-Dacho; Michael G Schwendinger; Otfried Kistner; Thomas R Kreil; Daniel Portsmouth; P Noel Barrett; Peter Brühl; Brian A Crowe; M Keith Howard
A cell culture-derived whole-virus H5N1 vaccine induces long-lasting cross-clade protective immunity in mice which is augmented by a homologous or heterologous booster vaccination.
Vaccine 2012;30(37):5533-40.
2012: Walter Wodal; Christina Piskernik; Daniel Portsmouth; Helga Savidis-Dacho; P Noel Barrett; Sogue Coulibaly; Falko G Falkner; Richard Fritz; Claudia Gaiswinkler; Christine Hohenadl; M Keith Howard; A Kerschbaum; Stefan Kiermayr; Otfried Kistner; Thomas R Kreil
A cell culture-derived whole-virus H9N2 vaccine induces high titer antibodies against hemagglutinin and neuraminidase and protects mice from severe lung pathology and weight loss after challenge with a highly virulent H9N2 isolate.
Vaccine 2012;30(31):4625-31.
2012: Hartmut J Ehrlich; Sandor Fritsch; Otfried Kistner; Herwig Kollaritsch; Thomas R Kreil; Alexandra Loew-Baselli; Friedrich Maritsch; Markus Müller; Borislava G Pavlova; Fritz Pinl; Daniel Portsmouth; Bernhard Schmitt; Markus Zeitlinger; Gerald Aichinger; P Noel Barrett
Pre-vaccination immunity and immune responses to a cell culture-derived whole-virus H1N1 vaccine are similar to a seasonal influenza vaccine.
Vaccine 2012;30(30):4543-51.
2012: Hartmut J Ehrlich; Wael El-Amin; Sandor Fritsch; Mary Kate Hart; Otfried Kistner; Daniel Portsmouth; Julia Singer; Gerald Aichinger; Gregory Berezuk; P Noel Barrett
Clinical development of a Vero cell culture-derived seasonal influenza vaccine.
Vaccine 2012;30(29):4377-86.
2012: Hartmut J Ehrlich; Wael El-Amin; Sandor Fritsch; Mary Kate Hart; Otfried Kistner; Daniel Portsmouth; Julia Singer; Gerald Aichinger; Gregory Berezuk; P Noel Barrett
A cell culture-derived influenza vaccine provides consistent protection against infection and reduces the duration and severity of disease in infected individuals.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012;54(7):946-54.
2012: Mark Cameron; Yong-Kyu Chu; Ronald C Couch; Ali Danesh; Yuan Fang; Ndingsa G Fomukong; Kevin S Harrod; Colleen B Jonsson; Alyson Kelvin; Otfried Kistner; Manfred Lauchart; Alberto J Leon; Qianjun Li; Stephane G Paquette; Longsi Ran; Thomas Rowe; Luoling Xu; Austin Anderson; Cheryl M Cameron; David J Kelvin
Lack of innate interferon responses during SARS coronavirus infection in a vaccination and reinfection ferret model.
PloS one 2012;7(9):e45842.
2011: Gerald Aichinger; John Aaskov; Wolfgang Draxler; Hartmut J Ehrlich; Sandor Fritsch; Annick Hens; Georg Holzer; Otfried Kistner; Thomas R Kreil; Jack Levy; Markus Müller; Fritz Pinl; Daniel Portsmouth; Christiane Thomasser; Pierre Van Damme; Michael Wolzt; P Noel Barrett
Safety and immunogenicity of an inactivated whole virus Vero cell-derived Ross River virus vaccine: a randomized trial.
Vaccine 2011;29(50):9376-84.
2011: Georg W Holzer; Sogue Coulibaly; Gerald Aichinger; Helga Savidis-Dacho; Josef Mayrhofer; Susanne Brunner; Karl Schmid; Otfried Kistner; John Aaskov; Falko G Falkner; Hartmut Ehrlich; P Noel Barrett; Thomas R Kreil
Evaluation of an inactivated Ross River virus vaccine in active and passive mouse immunization models and establishment of a correlate of protection.
Vaccine 2011;29(24):4132-41.
2011: P Noel Barrett; Gregory Berezuk; Sandor Fritsch; Gerald Aichinger; Mary Kate Hart; Wael El-Amin; Otfried Kistner; Hartmut J Ehrlich
Efficacy, safety, and immunogenicity of a Vero-cell-culture-derived trivalent influenza vaccine: a multicentre, double-blind, randomised, placebo-controlled trial.
Lancet 2011;377(9767):751-9.
2011: M Keith Howard; Otfried Kistner; Thomas R Kreil; Daniel Portsmouth; Nicolas Sabarth; Helga Savidis-Dacho; Hartmut J Ehrlich; P Noel Barrett
H5N1 whole-virus vaccine induces neutralizing antibodies in humans which are protective in a mouse passive transfer model.
PloS one 2011;6(8):e23791.
2010: Brian A Crowe; Peter Brühl; Marijan Gerencer; Michael G Schwendinger; Andreas Pilz; Otfried Kistner; Katrin Koelling-Schlebusch; Gerald Aichinger; Julia Singer; Markus Zeitlinger; Markus Müller; Hartmut Ehrlich; P Noel Barrett
Evaluation of the cellular immune responses induced by a non-adjuvanted inactivated whole virus A/H5N1/VN/1203 pandemic influenza vaccine in humans.
Vaccine 2010;29(2):166-73.
2010: Klaus K Orlinger; Georg W Holzer; Julia Schwaiger; Josef Mayrhofer; Karl Schmid; Otfried Kistner; P Noel Barrett; Falko G Falkner
An inactivated West Nile Virus vaccine derived from a chemically synthesized cDNA system.
Vaccine 2010;28(19):3318-24.
2010: André van Maurik; Nicolas Sabarth; Helga Savidis Dacho; Peter Brühl; Michael Schwendinger; Brian A Crowe; P Noel Barrett; Otfried Kistner; M Keith Howard
Seasonal influenza vaccine elicits heterosubtypic immunity against H5N1 that can be further boosted by H5N1 vaccination.
Vaccine 2010;28(7):1778-85.
2010: Annett Hessel; Michael Schwendinger; Daniela Fritz; Sogue Coulibaly; Georg W Holzer; Nicolas Sabarth; Otfried Kistner; Walter Wodal; Astrid Kerschbaum; Helga Savidis-Dacho; Brian A Crowe; Thomas R Kreil; P Noel Barrett; Falko G Falkner
A pandemic influenza H1N1 live vaccine based on modified vaccinia Ankara is highly immunogenic and protects mice in active and passive immunizations.
PloS one 2010;5(8):e12217.
2010: Otfried Kistner; Brian A Crowe; Walter Wodal; Astrid Kerschbaum; Helga Savidis-Dacho; Nicolas Sabarth; Falko G Falkner; Ines Mayerhofer; Wolfgang Mundt; Manfred Reiter; Leopold Grillberger; Christa Tauer; Michael Graninger; Alois Sachslehner; Michael Schwendinger; Peter Brühl; Thomas R Kreil; Hartmut J Ehrlich; P Noel Barrett
A whole virus pandemic influenza H1N1 vaccine is highly immunogenic and protective in active immunization and passive protection mouse models.
PloS one 2010;5(2):e9349.
2008: M Keith Howard; Otfried Kistner; P Noel Barrett
Pre-clinical development of cell culture (Vero)-derived H5N1 pandemic vaccines.
Biological chemistry 2008;389(5):569-77.
2007: Otfried Kistner; M Keith Howard; Martin Spruth; Walter Wodal; Peter Brühl; Marijan Gerencer; Brian A Crowe; Helga Savidis-Dacho; Ian Livey; Manfred Reiter; Ines Mayerhofer; Christa Tauer; Leopold Grillberger; Wolfgang Mundt; Falko G Falkner; P Noel Barrett
Cell culture (Vero) derived whole virus (H5N1) vaccine based on wild-type virus strain induces cross-protective immune responses.
Vaccine 2007;25(32):6028-36.
2007: Otfried Kistner; Noel P Barrett; Axel Brühmann; Manfred Reiter; Wolfgang Mundt; Helga Savidis-Dacho; Susanne Schober-Bendixen; Friedrich Dorner; John Aaskov
The preclinical testing of a formaldehyde inactivated Ross River virus vaccine designed for use in humans.
Vaccine 2007;25(25):4845-52.
2007: Thomas R Kreil; U Unger; S M Orth; G Petutschnig; Otfried Kistner; G Poelsler; Andreas Berting
H5N1 influenza virus and the safety of plasma products.
Transfusion 2007;47(3):452-9.
2006: Marijan Gerencer; Peter L Turecek; Otfried Kistner; Artur Mitterer; Helga Savidis-Dacho; Noel P Barrett
In vitro and in vivo anti-retroviral activity of the substance purified from the aqueous extract of Chelidonium majus L.
Antiviral research 2006;72(2):153-6.
2006: Martin Spruth; Otfried Kistner; Helga Savidis-Dacho; Elisabeth Hitter; Brian A Crowe; Marijan Gerencer; Peter Brühl; Leopold Grillberger; Manfred Reiter; Christa Tauer; Wolfgang Mundt; P Noel Barrett
A double-inactivated whole virus candidate SARS coronavirus vaccine stimulates neutralising and protective antibody responses.
Vaccine 2006;24(5):652-61.
2005: Andreas Berting; W Goerner; Martin Spruth; Otfried Kistner; Thomas R Kreil
Effective poxvirus removal by sterile filtration during manufacture of plasma derivatives.
Journal of medical virology 2005;75(4):603-7.
2003: Thomas R Kreil; Andreas Berting; Otfried Kistner; Johanna Kindermann
West Nile virus and the safety of plasma derivatives: verification of high safety margins, and the validity of predictions based on model virus data.
Transfusion 2003;43(8):1023-8.
2001: Otfried Kistner; Noel P Barrett; Wolfgang Mundt; Manfred Reiter; Susanne Schober-Bendixen; G Eder; Friedrich Dorner
[Development of a novel influenza vaccine derived from a continuous cell line].
ALTEX 2001;18(1):50-4.
2000: Peter Brühl; A Kerschbaum; Otfried Kistner; Noel P Barrett; Friedrich Dorner; Marijan Gerencer
Humoral and cell-mediated immunity to vero cell-derived influenza vaccine.
Vaccine 2000;19(9-10):1149-58.
1999: Otfried Kistner; P Noel Barrett; Wolfgang Mundt; Manfred Reiter; Susanne Schober-Bendixen; G Eder; Friedrich Dorner
A novel mammalian cell (Vero) derived influenza virus vaccine: development, characterization and industrial scale production.
Wiener klinische Wochenschrift 1999;111(5):207-14.
1999: Otfried Kistner; P Noel Barrett; Wolfgang Mundt; Manfred Reiter; Susanne Schober-Bendixen; G Eder; Friedrich Dorner
Development of a Vero cell-derived influenza whole virus vaccine.
Developments in biological standardization 1999;98():101-10; discussion 111.
1998: Otfried Kistner; P Noel Barrett; Wolfgang Mundt; Manfred Reiter; Susanne Schober-Bendixen; Friedrich Dorner
Development of a mammalian cell (Vero) derived candidate influenza virus vaccine.
Vaccine 1998;16(9-10):960-8.
1998: Marijan Gerencer; P Noel Barrett; Otfried Kistner; Artur Mitterer; Friedrich Dorner
Natural IgM antibodies in baby rabbit serum bind high-mannose glycans on HIV type 1 glycoprotein 120/160 and activate classic complement pathway.
AIDS research and human retroviruses 1998;14(7):599-605.
1996: Uwe Schlokat; B E Fischer; S Herlitschka; Gerhard Antoine; A Preininger; G Mohr; Michèle Himmelspach; Otfried Kistner; F G Falkner; Friedrich Dorner
Production of highly homogeneous and structurally intact recombinant von Willebrand factor multimers by furin-mediated propeptide removal in vitro.
Biotechnology and applied biochemistry 1996;24 ( Pt 3)():257-67.
1992: Falko G Falkner; Peter L Turecek; R T MacGillivray; W Bodemer; Friedrich Scheiflinger; S Kandels; Artur Mitterer; Otfried Kistner; Noel P Barrett; J Eibl
High level expression of active human prothrombin in a vaccinia virus expression system.
Thrombosis and haemostasis 1992;68(2):119-24.