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Yasuhiko Kitadai

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Shunsuke Shinmei; Jun Teishima; Katsuhiro Anami; Keisuke Goto; Tetsutaro Hayashi; Yasuhiko Kitadai; Akio Matsubara; Naohide Oue; Naoya Sakamoto; Kazuhiro Sentani; Wataru Yasui
MicroRNA-155 is a predictive marker for survival in patients with clear cell renal cell carcinoma.
Kei Shinagawa; Tomonori Sumida; Miwako Tanaka; Shinji Tanaka; Wataru Yasui; Yukihito Higashi; Yasuhiko Kitadai; Eiji Ohara; Mayu Ohnishi; Mieko Onoyama; Kazuaki Chayama
Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer.
Tomonori Sumida; Yasuhiko Kitadai; Kei Shinagawa; Miwako Tanaka; Michiyo Kodama; Mayu Ohnishi; Eiji Ohara; Shinji Tanaka; Wataru Yasui; Kazuaki Chayama
Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model.

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2013: Shunsuke Shinmei; Jun Teishima; Katsuhiro Anami; Keisuke Goto; Tetsutaro Hayashi; Yasuhiko Kitadai; Akio Matsubara; Naohide Oue; Naoya Sakamoto; Kazuhiro Sentani; Wataru Yasui
MicroRNA-155 is a predictive marker for survival in patients with clear cell renal cell carcinoma.
International journal of urology : official journal of the Japanese Urological Association 2013;20(5):468-77.
2013: Kei Shinagawa; Tomonori Sumida; Miwako Tanaka; Shinji Tanaka; Wataru Yasui; Yukihito Higashi; Yasuhiko Kitadai; Eiji Ohara; Mayu Ohnishi; Mieko Onoyama; Kazuaki Chayama
Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer.
International journal of cancer. Journal international du cancer 2013;132(4):813-23.
2011: Tomonori Sumida; Yasuhiko Kitadai; Kei Shinagawa; Miwako Tanaka; Michiyo Kodama; Mayu Ohnishi; Eiji Ohara; Shinji Tanaka; Wataru Yasui; Kazuaki Chayama
Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model.
International journal of cancer. Journal international du cancer 2011;128(9):2050-62.
2010: Kei Shinagawa; Yasuhiko Kitadai; Miwako Tanaka; Tomonori Sumida; Michiyo Kodama; Yukihito Higashi; Shinji Tanaka; Wataru Yasui; Kazuaki Chayama
Mesenchymal stem cells enhance growth and metastasis of colon cancer.
International journal of cancer. Journal international du cancer 2010;127(10):2323-33.
2010: Miwako Tanaka; Yasuhiko Kitadai; Michiyo Kodama; Kei Shinagawa; Tomonori Sumida; Shinji Tanaka; Naohide Oue; Wataru Yasui; Kazuaki Chayama
Potential role for vascular endothelial growth factor-D as an autocrine factor for human gastric carcinoma cells.
Cancer science 2010;101(10):2121-7.
2010: Michiyo Kodama; Yasuhiko Kitadai; Tomonori Sumida; Mayu Ohnishi; Eiji Ohara; Miwako Tanaka; Kei Shinagawa; Shinji Tanaka; Wataru Yasui; Kazuaki Chayama
Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor β is associated with lymphatic metastasis in human gastric carcinoma.
Cancer science 2010;101(9):1984-9.
2010: Shiro Oka; Shinji Tanaka; Shigeto Yoshida; Toru Hiyama; Yoshitaka Ueno; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Kazuaki Chayama
A water-soluble extract from culture medium of Ganoderma lucidum mycelia suppresses the development of colorectal adenomas.
Hiroshima journal of medical sciences 2010;59(1):1-6.
2010: Yasuhiko Kitadai
Angiogenesis and lymphangiogenesis of gastric cancer.
Journal of oncology 2010;2010():468725.
2009: Akira Tari; Hideki Asaoku; Kozo Kashiwado; Tadashi Yoshino; Yasuhiko Kitadai; Shinji Tanaka; Megumu Fujihara
Predictive value of endoscopy and endoscopic ultrasonography for regression of gastric diffuse large B-cell lymphomas after Helicobacter pylori eradication.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2009;21(4):219-27.
2009: Hideki Yamamoto; Yasuhiko Kitadai; Hideki Yamamoto; Naohide Oue; Hideki Ohdan; Wataru Yasui; Akira Kikuchi
Laminin gamma2 mediates Wnt5a-induced invasion of gastric cancer cells.
Gastroenterology 2009;137(1):242-52, 252.e1-6.
2009: Tomonori Sumida; Yasuhiko Kitadai; Toru Hiyama; Kei Shinagawa; Miwako Tanaka; Michiyo Kodama; Hiroshi Masuda; Masanori Ito; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Antibodies to Helicobacter pylori and CagA protein are associated with the response to antibacterial therapy in patients with H. pylori-positive API2-MALT1-negative gastric MALT lymphoma.
Cancer science 2009;100(6):1075-81.
2008: Michiyo Kodama; Yasuhiko Kitadai; Miwako Tanaka; Toshio Kuwai; Shinji Tanaka; Naohide Oue; Wataru Yasui; Kazuaki Chayama
Vascular endothelial growth factor C stimulates progression of human gastric cancer via both autocrine and paracrine mechanisms.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(22):7205-14.
2008: Tsuyoshi Kuroda; Masanori Ito; Yoshihiro Wada; Yasuhiko Kitadai; Shinji Tanaka; Kazuhiro Yoshida; Masaharu Yoshihara; Ken Haruma; Sven Merdh; Kazuaki Chayama
Presence of poorly differentiated component correlated with submucosal invasion in the early diffuse-type gastric cancer.
Hepato-gastroenterology 2008;55(88):2264-8.
2008: Miwako Tanaka; Yasuhiko Kitadai; Michiyo Kodama; Tomonori Sumida; Kei Shinagawa; Kyoko Yoshioka; Yutaka Mitsuoka; Hiroshi Masuda; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
[A case report of anaphylactoid purpura with acute abdominal pain secondary to trauma caused by traffic accident].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2008;105(4):566-71.
2008: M Kodama; Yasuhiko Kitadai; T Shishido; Masaru Shimamoto; Akira Fukumoto; H Masuda; Shinji Tanaka; Masaharu Yoshihara; A Sakai; H Nakayama; Kazuaki Chayama
Primary follicular lymphoma of the gastrointestinal tract: a retrospective case series.
Endoscopy 2008;40(4):343-6.
2008: Toshio Kuwai; Toru Nakamura; Sun-Jin Kim; Takamitsu Sasaki; Yasuhiko Kitadai; Robert R Langley; Dominic Fan; Stanley R Hamilton; Isaiah J Fidler
Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors.
The American journal of pathology 2008;172(2):358-66.
2008: Toshio Kuwai; Toru Nakamura; Takamitsu Sasaki; Yasuhiko Kitadai; Jang-Seong Kim; Robert R Langley; Dominic Fan; Xuemei Wang; Kim-Anh Do; Sun-Jin Kim; Isaiah J Fidler
Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy.
Clinical & experimental metastasis 2008;25(4):477-89.
2007: Takamitsu Sasaki; Yasuhiko Kitadai; Toru Nakamura; Jang-Seong Kim; Rachel Tsan; Toshio Kuwai; Robert R Langley; Dominic Fan; Sun-Jin Kim; Isaiah J Fidler
Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude mice.
Neoplasia (New York, N.Y.) 2007;9(12):1066-77.
2007: Toru Nakamura; Toshio Kuwai; Yasuhiko Kitadai; Takamitsu Sasaki; Dominic Fan; Kevin R Coombes; Sun-Jin Kim; Isaiah J Fidler
Zonal heterogeneity for gene expression in human pancreatic carcinoma.
Cancer research 2007;67(16):7597-604.
2007: Shunji Matsumura; Naohide Oue; Yoshitsugu Mitani; Yasuhiko Kitadai; Wataru Yasui
DNA demethylation of vascular endothelial growth factor-C is associated with gene expression and its possible involvement of lymphangiogenesis in gastric cancer.
International journal of cancer. Journal international du cancer 2007;120(8):1689-95.
2007: Shigeru Kimura; Shinji Tanaka; Hiroaki Kusunoki; Yasuhiko Kitadai; Masaharu Sumii; Susumu Tazuma; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Cavernous hemangioma in the ascending colon treated by endoscopic mucosal resection.
Journal of gastroenterology and hepatology 2007;22(2):280-1.
2007: Michiyo Kodama; Yasuhiko Kitadai; Masanori Ito; Hirohisa Kai; Hiroshi Masuda; Shinji Tanaka; Masaharu Yoshihara; Kingo Fujimura; Kazuaki Chayama
Immune response to CagA protein is associated with improved platelet count after Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura.
Helicobacter 2007;12(1):36-42.
2007: Akira Tari; Yasuhiko Kitadai; Masaharu Sumii; Atsunori Sasaki; Hiroshi Tani; Sinji Tanaka; Kazuaki Chayama
Basis of decreased risk of gastric cancer in severe atrophic gastritis with eradication of Helicobacter pylori.
Digestive diseases and sciences 2007;52(1):232-9.
2006: Yasuhiko Kitadai; Takamitsu Sasaki; Toshio Kuwai; Toru Nakamura; Corazon D Bucana; Isaiah J Fidler
Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma.
The American journal of pathology 2006;169(6):2054-65.
2006: Songde Cho; Yasuhiko Kitadai; Shigeto Yoshida; Shinji Tanaka; Masaharu Yoshihara; Kazuhiro Yoshida; Kazuaki Chayama
Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions.
International journal of molecular medicine 2006;18(6):1067-71.
2006: Yasuhiko Kitadai; Takamitsu Sasaki; Toshio Kuwai; Toru Nakamura; Corazon D Bucana; Stanley R Hamilton; Isaiah J Fidler
Expression of activated platelet-derived growth factor receptor in stromal cells of human colon carcinomas is associated with metastatic potential.
International journal of cancer. Journal international du cancer 2006;119(11):2567-74.
2006: Yoshitaka Ueno; Shinji Tanaka; Hiroyuki Kanao; Kyoko Yoshioka; Tsuyoshi Hatakeyama; Masaru Shimamoto; Yoshihiro Miyanaka; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Kazuaki Chayama
A case of Crohn's disease with hydronephrosis caused by ureteropelvic junction obstruction.
European journal of gastroenterology & hepatology 2006;18(9):1015-8.
2006: Lin Yang; Hector Avila; Heng Wang; Jose G Trevino; Gary E Gallick; Yasuhiko Kitadai; Takamitsu Sasaki; Douglas D Boyd
Plasticity in urokinase-type plasminogen activator receptor (uPAR) display in colon cancer yields metastable subpopulations oscillating in cell surface uPAR density--implications in tumor progression.
Cancer research 2006;66(16):7957-67.
2006: Takehiko Ochiumi; Yasuhiko Kitadai; Shinji Tanaka; Morihisa Akagi; Masaharu Yoshihara; Kazuaki Chayama
Neuropilin-1 is involved in regulation of apoptosis and migration of human colon cancer.
International journal of oncology 2006;29(1):105-16.
2006: Songde Cho; Yasuhiko Kitadai; Shigeto Yoshida; Shinji Tanaka; Masaharu Yoshihara; Kazuhiro Yoshida; Kazuaki Chayama
Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach.
International journal of oncology 2006;28(6):1361-7.
2006: Tadashi Yoshino; Shigeo Nakamura; Yoshihiro Matsuno; Atsushi Ochiai; Takio Yokoi; Yasuhiko Kitadai; Junji Suzumiya; Kensei Tobinai; Yukio Kobayashi; Ichiro Oda; Kiyomi Mera; Atsushi Ohtsu; Satoshi Ishikura
Epstein-Barr virus involvement is a predictive factor for the resistance to chemoradiotherapy of gastric diffuse large B-cell lymphoma.
Cancer science 2006;97(2):163-6.
2005: Kenji Yokoi; Takamitsu Sasaki; Corazon D Bucana; Dominic Fan; Cheryl H Baker; Yasuhiko Kitadai; Toshio Kuwai; James L Abbruzzese; Isaiah J Fidler
Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model.
Cancer research 2005;65(22):10371-80.
2005: Tsuyoshi Kuroda; Yasuhiko Kitadai; Shinji Tanaka; Xiaoqin Yang; Naofumi Mukaida; Masaharu Yoshihara; Kazuaki Chayama
Monocyte chemoattractant protein-1 transfection induces angiogenesis and tumorigenesis of gastric carcinoma in nude mice via macrophage recruitment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7629-36.
2005: Seiji Onogawa; Yasuhiko Kitadai; Toru Amioka; Michiyo Kodama; Songde Cho; Tsuyoshi Kuroda; Takehiko Ochiumi; Shigeru Kimura; Toshio Kuwai; Shinji Tanaka; Kazuaki Chayama
Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in early gastric carcinoma: correlation with clinicopathological parameters.
Cancer letters 2005;226(1):85-90.
2005: Masanori Ito; Shinji Tanaka; Sunjin Kim; Kazumasa Tahara; Yuzuru Kawamura; Masaharu Sumii; Yoshihiko Takehara; Kozo Hayashi; Eiichi Okamoto; Masaki Kunihiro; Toshiro Kunita; Shinobu Imagawa; Shunsuke Takata; Hiroyuki Ueda; Yasuo Egi; Toru Hiyama; Yoshitaka Ueno; Yasuhiko Kitadai; Masaharu Yoshihara; Kazuaki Chayama
A combination of the Helicobacter pylori stool antigen test and urea breath test is useful for clinical evaluation of eradication therapy: a multicenter study.
Journal of gastroenterology and hepatology 2005;20(8):1241-5.
2005: Yasuhiko Kitadai; Michiyo Kodama; Songde Cho; Tsuyoshi Kuroda; Takehiko Ochiumi; Shigeru Kimura; Shinji Tanaka; Shunji Matsumura; Wataru Yasui; Kazuaki Chayama
Quantitative analysis of lymphangiogenic markers for predicting metastasis of human gastric carcinoma to lymph nodes.
International journal of cancer. Journal international du cancer 2005;115(3):388-92.
2005: Hirohisa Kai; Yasuhiko Kitadai; Michiyo Kodama; Songde Cho; Tsuyoshi Kuroda; Masanori Ito; Shinji Tanaka; Yasukazu Ohmoto; Kazuaki Chayama
Involvement of proinflammatory cytokines IL-1beta and IL-6 in progression of human gastric carcinoma.
Anticancer research 2005;25(2A):709-13.
2005: Masanori Ito; Shinji Tanaka; Shunsuke Takata; Shiro Oka; Shinobu Imagawa; Hiroyuki Ueda; Yasuo Egi; Yasuhiko Kitadai; W Yasui; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Morphological changes in human gastric tumours after eradication therapy of Helicobacter pylori in a short-term follow-up.
Alimentary pharmacology & therapeutics 2005;21(5):559-66.
2005: Hideyuki Shima; Toru Hiyama; Shinji Tanaka; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Koji Arihiro; Kazuaki Chayama
Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma.
Pathobiology : journal of immunopathology, molecular and cellular biology 2005;72(4):220-4.
2005: Shigeru Kimura; Yasuhiko Kitadai; Toshio Kuwai; Shinji Tanaka; Jun Hihara; Kazuhiro Yoshida; Tetsuya Toge; Kazuaki Chayama
Expression of p53 protein in esophageal squamous cell carcinoma: relation to hypoxia-inducible factor-1alpha, angiogenesis and apoptosis.
Pathobiology : journal of immunopathology, molecular and cellular biology 2005;72(4):179-85.
2005: Yoichi Hamai; Shunji Matsumura; Keisuke Matsusaki; Yasuhiko Kitadai; Kazuhiro Yoshida; Yoshiyuki Yamaguchi; Kazue Imai; Kei Nakachi; Tetsuya Toge; Wataru Yasui
A single nucleotide polymorphism in the 5' untranslated region of the EGF gene is associated with occurrence and malignant progression of gastric cancer.
Pathobiology : journal of immunopathology, molecular and cellular biology 2005;72(3):133-8.
2005: Yoshitaka Ueno; Shinji Tanaka; Masaru Shimamoto; Yoshihiro Miyanaka; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Masaharu Sumii; Kazuaki Chayama
Infliximab therapy for Crohn's disease in a patient with chronic hepatitis B.
Digestive diseases and sciences 2005;50(1):163-6.
2005: Shunji Matsumura; Naohide Oue; Hirofumi Nakayama; Yasuhiko Kitadai; Kazuhiro Yoshida; Yoshiyuki Yamaguchi; Kazue Imai; Kei Nakachi; Keisuke Matsusaki; Kazuaki Chayama; Wataru Yasui
A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer.
Journal of cancer research and clinical oncology 2005;131(1):19-25.
2004: Yasuhiro Oshimo; Kazuya Kuraoka; Hirofumi Nakayama; Yasuhiko Kitadai; Kazuhiro Yoshida; Kazuaki Chayama; Wataru Yasui
Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma.
International journal of cancer. Journal international du cancer 2004;112(6):1003-9.
2004: Shinji Tanaka; Ken Haruma; Masaki Kunihiro; Shinji Nagata; Yasuhiko Kitadai; Noriaki Manabe; Masaharu Sumii; Masaharu Yoshihara; Goro Kajiyama; Kazuaki Chayama
Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study.
Hiroshima journal of medical sciences 2004;53(3-4):39-45.
2004: Masaki Kunihiro; Shinji Tanaka; Masaharu Sumii; Yoshitaka Ueno; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation.
Inflammatory bowel diseases 2004;10(6):737-44.
2004: Toshio Kuwai; Yasuhiko Kitadai; Shinji Tanaka; Tsuyoshi Kuroda; Takehiko Ochiumi; Shunji Matsumura; Naohide Oue; Wataru Yasui; Mika Kaneyasu; Keiji Tanimoto; Masahiko Nishiyama; Kazuaki Chayama
Single nucleotide polymorphism in the hypoxia-inducible factor-1alpha gene in colorectal carcinoma.
Oncology reports 2004;12(5):1033-7.
2004: Shigeru Kimura; Yasuhiko Kitadai; Shinji Tanaka; Toshio Kuwai; Jun Hihara; Kazuhiro Yoshida; Tetsuya Toge; Kazuaki Chayama
Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human oesophageal squamous cell carcinoma.
European journal of cancer (Oxford, England : 1990) 2004;40(12):1904-12.
2004: Hideyuki Shima; Toru Hiyama; Shinji Tanaka; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Koji Arihiro; Ken Haruma; Kazuaki Chayama
Frequent loss of heterozygosity on chromosome 10p14-p15 in esophageal dysplasia and squamous cell carcinoma.
Oncology reports 2004;12(2):333-7.
2004: Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Shogo Sasao; Kazuhiro Kose; Hideyuki Shima; Handan Tuncel; Yoshitaka Ueno; Masanori Ito; Yasuhiko Kitadai; Wataru Yasui; Ken Haruma; Kazuaki Chayama
Chromosomal and microsatellite instability in sporadic gastric cancer.
Journal of gastroenterology and hepatology 2004;19(7):756-60.
2004: Seiji Onogawa; Yasuhiko Kitadai; Shinji Tanaka; Toshio Kuwai; Tsuyoshi Kuroda; Kazuaki Chayama
Regulation of vascular endothelial growth factor (VEGF)-C and VEGF-D expression by the organ microenvironment in human colon carcinoma.
European journal of cancer (Oxford, England : 1990) 2004;40(10):1604-9.
2004: H Kai; Masanori Ito; Yasuhiko Kitadai; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Chronic gastritis with expression of inducible nitric oxide synthase is associated with high expression of interleukin-6 and hypergastrinaemia.
Alimentary pharmacology & therapeutics 2004;19(12):1309-14.
2004: Yasuhiro Oshimo; Naohide Oue; Yoshitsugu Mitani; Hirofumi Nakayama; Yasuhiko Kitadai; Kazuhiro Yoshida; Kazuaki Chayama; Wataru Yasui
Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma.
International journal of cancer. Journal international du cancer 2004;110(2):212-8.
2004: Shigeto Yoshida; Shinji Tanaka; Daisuke Kamino; Madoka Nakao; Shiro Oka; Yasuhiko Kitadai; Norihiko Hayakawa; Ken Haruma; Kazuaki Chayama
Initial experience with catheter probe US when using a multibending endoscope.
Gastrointestinal endoscopy 2004;59(7):889-94.
2004: Shunji Matsumura; Naohide Oue; Yasuhiko Kitadai; Kazuaki Chayama; Kazuhiro Yoshida; Yoshiyuki Yamaguchi; Tetsuya Toge; Kazue Imai; Kei Nakachi; Wataru Yasui
A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer.
Journal of cancer research and clinical oncology 2004;130(5):259-65.
2004: Takehiko Ochiumi; Shinji Tanaka; Shiro Oka; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Ken Haruma; Kazuaki Chayama
Clinical significance of angiopoietin-2 expression at the deepest invasive tumor site of advanced colorectal carcinoma.
International journal of oncology 2004;24(3):539-47.
2004: Toshio Kuwai; Yasuhiko Kitadai; Shinji Tanaka; Toru Hiyama; Keiji Tanimoto; Kazuaki Chayama
Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1alpha.
Cancer science 2004;95(2):149-53.
2004: Shiro Oka; Shinji Tanaka; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types.
Gastrointestinal endoscopy 2004;59(2):213-9.
2004: Yasuhiko Kitadai; Seiji Onogawa; Toshio Kuwai; Shunji Matsumura; Hiroshige Hamada; Masanori Ito; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Angiogenic switch occurs during the precancerous stage of human esophageal squamous cell carcinoma.
Oncology reports 2004;11(2):315-9.
2004: Atsunori Sasaki; Yasuhiko Kitadai; Masanori Ito; Shinji Tanaka; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Mucin phenotype and background mucosa of intramucosal differentiated-type adenocarcinoma of the stomach.
Oncology 2004;66(5):379-87.
2004: Yasuhiro Oshimo; Naohide Oue; Yoshitsugu Mitani; Hirofumi Nakayama; Yasuhiko Kitadai; Kazuhiro Yoshida; Yoshiaki Ito; Kazuaki Chayama; Wataru Yasui
Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma.
Pathobiology : journal of immunopathology, molecular and cellular biology 2004;71(3):137-43.
2004: Seiji Onogawa; Yasuhiko Kitadai; Shinji Tanaka; Toshio Kuwai; Shigeru Kimura; Kazuaki Chayama
Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma.
Cancer science 2004;95(1):32-9.
2004: Toru Amioka; Yasuhiko Kitadai; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions.
Oncology reports 2004;11(1):51-5.
2003: Yasuhiro Oshimo; Hirofumi Nakayama; Reiko Ito; Yasuhiko Kitadai; Kazuhiro Yoshida; Kazuaki Chayama; Wataru Yasui
Promoter methylation of cyclin D2 gene in gastric carcinoma.
International journal of oncology 2003;23(6):1663-70.
2003: Yasuhiko Kitadai; Atsunori Sasaki; Masanori Ito; Shinji Tanaka; Naohide Oue; Wataru Yasui; Miki Aihara; Kenichi Imagawa; Ken Haruma; Kazuaki Chayama
Helicobacter pylori infection influences expression of genes related to angiogenesis and invasion in human gastric carcinoma cells.
Biochemical and biophysical research communications 2003;311(4):809-14.
2003: Shiro Oka; Shinji Tanaka; Shinji Nagata; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Clinicopathologic features and endoscopic resection of early primary nonampullary duodenal carcinoma.
Journal of clinical gastroenterology 2003;37(5):381-6.
2003: Toru Hiyama; Shinji Tanaka; Hideyuki Shima; Kazuhiro Kose; Handan Tuncel; Masanori Ito; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Somatic mutation in mitochondrial DNA and nuclear microsatellite instability in gastric cancer.
Oncology reports 2003;10(6):1837-41.
2003: Hiroki Kuniyasu; Hitoshi Ohmori; Takamistu Sasaki; Tomonori Sasahira; Kazuhiro Yoshida; Yasuhiko Kitadai; Isaiah J Fidler
Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):4802-10.
2003: Toru Hiyama; Shinji Tanaka; Hiroshi Masuda; Hideyuki Shima; Kazuhiro Kose; Handan Tuncel; Masanori Ito; Yasuhiko Kitadai; Masaharu Sumii; Naomi Uemura; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Prevalence of Helicobacter pylori resistance to clarithromycin and metronidazole determined by 23S ribosomal RNA and rdxA gene analyses in Hiroshima, Japan.
Journal of gastroenterology and hepatology 2003;18(10):1202-7.
2003: Toshio Kuwai; Shinji Tanaka; Eijiro Kaio; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types.
International journal of molecular medicine 2003;12(4):437-42.
2003: Eijiro Kaio; Shinji Tanaka; Shiro Oka; Toru Hiyama; Yasuhiko Kitadai; Ken Haruma; Kazuaki Chayama
Clinical significance of thrombospondin-1 expression in relation to vascular endothelial growth factor and interleukin-10 expression at the deepest invasive tumor site of advanced colorectal carcinoma.
International journal of oncology 2003;23(4):901-11.
2003: Shunji Matsumura; Naohide Oue; Reiko Ito; Hirofumi Nakayama; Yasuhiko Kitadai; Hiroshi Yokozaki; Kazuaki Chayama; Wataru Yasui
The promoter methylation status of the DNA repair gene O6-methylguanine-DNA methyltransferase in ulcerative colitis.
Virchows Archiv : an international journal of pathology 2003;443(4):518-23.
2003: Toru Hiyama; Shinji Tanaka; Hiroshi Masuda; Hideyuki Shima; Kazuhiro Kose; Handan Tuncel; Masanori Ito; Yasuhiko Kitadai; Masaharu Sumii; Naomi Uemura; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
p53 expression, K-ras gene mutation and microsatellite instability in gastric B-cell lymphomas.
Journal of gastroenterology and hepatology 2003;18(9):1047-53.
2003: Toru Hiyama; Shinji Tanaka; Hideyuki Shima; Kazuhiro Kose; Yasuhiko Kitadai; Masanori Ito; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer.
Oncology reports 2003;10(5):1297-9.
2003: Toru Hiyama; Shinji Tanaka; Hideyuki Shima; Kazuhiro Kose; Yasuhiko Kitadai; Masanori Ito; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer.
International journal of molecular medicine 2003;12(2):169-74.
2003: Kazuya Kuraoka; Naohide Oue; Hiroshi Yokozaki; Yasuhiko Kitadai; Reiko Ito; Hirofumi Nakayama; Wataru Yasui
Correlation of a single nucleotide polymorphism in the E-cadherin gene promoter with tumorigenesis and progression of gastric carcinoma in Japan.
International journal of oncology 2003;23(2):421-7.
2003: Masanori Ito; Shinji Tanaka; Sunjin Kim; Toshio Kuwai; Norimasa Matsutani; Tomoari Kamada; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
The specific expression of hypoxia inducible factor-1alpha in human gastric mucosa induced by nonsteroidal anti-inflammatory drugs.
Alimentary pharmacology & therapeutics 2003;18 Suppl 1():90-8.
2003: Ryoji Takahashi; Shinji Tanaka; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Sumii; Ken Haruma; Kazuaki Chayama
Hypoxia-inducible factor-1alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach.
Oncology reports 2003;10(4):797-802.
2003: Toshio Kuwai; Yasuhiko Kitadai; Shinji Tanaka; Seiji Onogawa; Norimasa Matsutani; Eijiro Kaio; Masanori Ito; Kazuaki Chayama
Expression of hypoxia-inducible factor-1alpha is associated with tumor vascularization in human colorectal carcinoma.
International journal of cancer. Journal international du cancer 2003;105(2):176-81.
2003: Jie Zhang; Reiko Ito; Naohide Oue; Xudong Zhu; Yasuhiko Kitadai; Kazuhiro Yoshida; Hirofumi Nakayama; Wataru Yasui
Expression of thrombospondin-1 is correlated with microvessel density in gastric carcinoma.
Virchows Archiv : an international journal of pathology 2003;442(6):563-8.
2003: Akira Tari; Kanji Kodama; Yasuhiko Kitadai; Masahiro Ohta; Koji Sumii; Goro Kajiyama
Is apoptosis in antral mucosa correlated with serum nitrite concentration in Japanese Helicobacter pylori-infected patients?
Journal of gastroenterology and hepatology 2003;18(5):498-504.
2003: Tomoari Kamada; Ken Haruma; Hiroaki Kusunoki; Masaki Miyamoto; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Kazuaki Chayama; Kazumasa Tahara; Yuzuru Kawamura
Significance of an exaggerated meal-stimulated gastrin response in pathogenesis of Helicobacter pylori-negative duodenal ulcer.
Digestive diseases and sciences 2003;48(4):644-51.
2003: Hideyuki Shima; Shinji Tanaka; Toshio Kuwai; Toru Hiyama; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Minute depressed colon cancer with submucosal invasion.
Gastrointestinal endoscopy 2003;57(4):564-5.
2003: Masahiro Ohta; Yasuhiko Kitadai; Shinji Tanaka; Masaharu Yoshihara; Wataru Yasui; Naofumi Mukaida; Ken Haruma; Kazuaki Chayama
Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human gastric carcinomas.
International journal of oncology 2003;22(4):773-8.
2003: Yukio Kuwada; Tamito Sasaki; Kenji Morinaka; Yasuhiko Kitadai; Naofumi Mukaida; Kazuaki Chayama
Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells.
International journal of oncology 2003;22(4):765-71.
2003: Atsunori Sasaki; Yasuhiko Kitadai; Masanori Ito; Masaharu Sumii; Shinji Tanaka; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Helicobacter pylori infection influences tumor growth of human gastric carcinomas.
Scandinavian journal of gastroenterology 2003;38(2):153-8.
2003: Seiji Onogawa; Shinji Tanaka; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Small rectal carcinoid with lymph node metastasis diagnosed prior to treatment.
European journal of gastroenterology & hepatology 2003;15(2):195-7.
2003: Hiroki Kuniyasu; Yasuhiko Kitadai; Hiroshi Mieno; Wataru Yasui
Helicobactor pylori infection is closely associated with telomere reduction in gastric mucosa.
Oncology 2003;65(3):275-82.
2003: Naohide Oue; Shunji Matsumura; Hirofumi Nakayama; Yasuhiko Kitadai; Kiyomi Taniyama; Keisuke Matsusaki; Wataru Yasui
Reduced expression of the TSP1 gene and its association with promoter hypermethylation in gastric carcinoma.
Oncology 2003;64(4):423-9.
2003: Ryoji Takahashi; Shinji Tanaka; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach.
Oncology 2003;64(3):266-74.
2003: Eijiro Kaio; Shinji Tanaka; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma.
Oncology 2003;64(1):61-73.
2002: Masahiro Ohta; Yasuhiko Kitadai; Shinji Tanaka; Masaharu Yoshihara; Wataru Yasui; Naofumi Mukaida; Ken Haruma; Kazuaki Chayama
Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human esophageal squamous cell carcinomas.
International journal of cancer. Journal international du cancer 2002;102(3):220-4.
2002: Yutaka Takahashi; Yasuhiko Kitadai; Lee M Ellis; Corazon D Bucana; Isaiah J Fidler; Masayoshi Mai
Multiparametric in situ mRNA hybridization analysis of gastric biopsies predicts lymph node metastasis in patients with gastric carcinoma.
Japanese journal of cancer research : Gann 2002;93(11):1258-65.
2002: S Oka; Shinji Tanaka; Toru Hiyama; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Human telomerase reverse transcriptase, p53 and Ki-67 expression and apoptosis in colorectal serrated adenoma.
Scandinavian journal of gastroenterology 2002;37(10):1194-200.
2002: Shinji Tanaka; Shinji Nagata; Shiro Oka; Toshio Kuwai; Tadamasa Tamura; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Determining depth of invasion by VN pit pattern analysis in submucosal colorectal carcinoma.
Oncology reports 2002;9(5):1005-8.
2002: Masanori Ito; Ken Haruma; Tomoari Kamada; M Mihara; Sunjin Kim; Yasuhiko Kitadai; Masaharu Sumii; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Helicobacter pylori eradication therapy improves atrophic gastritis and intestinal metaplasia: a 5-year prospective study of patients with atrophic gastritis.
Alimentary pharmacology & therapeutics 2002;16(8):1449-56.
2002: Shinji Nagata; Shinji Tanaka; Ken Haruma; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto; Kazuaki Chayama
Advanced colorectal carcinoma smaller than 10 mm in maximum diameter with special reference to clinicopathologic and molecular features: a report of 3 cases.
Gastrointestinal endoscopy 2002;56(2):299-303.
2002: Toru Hiyama; Shinji Tanaka; Yasuhiko Kitadai; Masanori Ito; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
p53 Codon 72 polymorphism in gastric cancer susceptibility in patients with Helicobacter pylori-associated chronic gastritis.
International journal of cancer. Journal international du cancer 2002;100(3):304-8.
2002: T Amioka; Yasuhiko Kitadai; Shinji Tanaka; Ken Haruma; Masaharu Yoshihara; Wataru Yasui; Kazuaki Chayama
Vascular endothelial growth factor-C expression predicts lymph node metastasis of human gastric carcinomas invading the submucosa.
European journal of cancer (Oxford, England : 1990) 2002;38(10):1413-9.
2002: Hideharu Okanobu; Jiro Hata; Ken Haruma; S Matsumura; Shigeto Yoshida; Yasuhiko Kitadai; Shinji Tanaka; Kazuaki Chayama
Preoperative assessment of gastric cancer vascularity by flash echo imaging.
Scandinavian journal of gastroenterology 2002;37(5):608-12.
2002: Seiji Onogawa; Shinji Tanaka; Shiro Oka; Masao Morihara; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Clinical significance of angiogenesis in rectal carcinoid tumors.
Oncology reports 2002;9(3):489-94.
2002: Ken Haruma; Masanori Ito; S Kido; Noriaki Manabe; Yasuhiko Kitadai; M Sumii; S Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis.
Digestive diseases and sciences 2002;47(4):862-7.
2002: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Hiroshi Masuda; Masaki Miyamoto; Shinji Tanaka; Masaharu Yoshihara; Fumio Shimamoto; Kazuaki Chayama
K-ras mutation in helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer.
International journal of cancer. Journal international du cancer 2002;97(5):562-6.
2002: Tomoari Kamada; Kazuaki Chayama; Ken Haruma; Masaharu Yoshihara; Masanori Ito; Yasuhiko Kitadai; Yuzuru Kawamura
[Non-ulcer dyspepsia and H. pylori].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 2():774-8.
2002: Tomoari Kamada; Kazuaki Chayama; Ken Haruma; Masaharu Yoshihara; Masanori Ito; Yasuhiko Kitadai; Yuzuru Kawamura
[The analysis of the recurrence ulcer after H. pylori eradication].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 2():501-5.
2002: Akira Furudoi; Shinji Tanaka; Ken Haruma; Yasuhiko Kitadai; Masaharu Yoshihara; Kazuaki Chayama; Fumio Shimamoto
Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma.
Oncology 2002;62(2):157-66.
2001: S Nagata; Shinji Tanaka; Ken Haruma; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto; Nobuoki Kohno; Kazuaki Chayama
MUC1 and cathepsin D expression in early colorectal carcinoma showing V type pit pattern.
International journal of oncology 2001;19(4):665-72.
2001: X Chen; Ken Haruma; Tomoari Kamada; N Hartori; Masaharu Yoshihara; Yasuhiko Kitadai; Shinji Tanaka; Koji Sumii; Kazuaki Chayama
A low 13C-urea breath test value is associated with increased risk of gastric cancer.
Journal of gastroenterology 2001;36(9):601-5.
2001: Yasuhiko Kitadai; Toru Amioka; Ken Haruma; Shinji Tanaka; Masaharu Yoshihara; K Sumii; Norimasa Matsutani; Wataru Yasui; Kazuaki Chayama
Clinicopathological significance of vascular endothelial growth factor (VEGF)-C in human esophageal squamous cell carcinomas.
International journal of cancer. Journal international du cancer 2001;93(5):662-6.
2001: H Oh-e; Shinji Tanaka; Yasuhiko Kitadai; Fumio Shimamoto; Masaharu Yoshihara; Ken Haruma
Angiogenesis at the site of deepest penetration predicts lymph node metastasis of submucosal colorectal cancer.
Diseases of the colon and rectum 2001;44(8):1129-36.
2001: S Kido; Yasuhiko Kitadai; N Hattori; Ken Haruma; T Kido; M Ohta; Shinji Tanaka; Masaharu Yoshihara; K Sumii; Y Ohmoto; Kazuaki Chayama
Interleukin 8 and vascular endothelial growth factor -- prognostic factors in human gastric carcinomas?
European journal of cancer (Oxford, England : 1990) 2001;37(12):1482-7.
2001: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Hiroshi Masuda; Masaki Miyamoto; Masanori Ito; Tomoari Kamada; Shinji Tanaka; Naomi Uemura; Masaharu Yoshihara; Koji Sumii; Fumio Shimamoto; Kazuaki Chayama
Clinicopathological features of gastric mucosa-associated lymphoid tissue lymphoma: a comparison with diffuse large B-cell lymphoma without a mucosa-associated lymphoid tissue lymphoma component.
Journal of gastroenterology and hepatology 2001;16(7):734-9.
2001: Shinji Tanaka; Ken Haruma; Shiro Oka; R Takahashi; Masaki Kunihiro; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto; Kazuaki Chayama
Clinicopathologic features and endoscopic treatment of superficially spreading colorectal neoplasms larger than 20 mm.
Gastrointestinal endoscopy 2001;54(1):62-6.
2001: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Masanori Ito; Hiroshi Masuda; Masaki Miyamoto; Shinji Tanaka; Masaharu Yoshihara; Koji Sumii; Fumio Shimamoto; Kazuaki Chayama
Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with analysis of p53 and K-ras alteration and microsatellite instability.
International journal of oncology 2001;18(6):1207-12.
2001: Masanori Ito; Ken Haruma; T Kamada; Yasuhiko Kitadai; T Hidaka; T Tsuda; H Komatsu; T Fukuhara; Masaharu Yoshihara; Kazuaki Chayama
Reduction in the incidence of Helicobacter pylori-associated carcinoma in Japanese young adults.
Oncology reports 2001;8(3):633-6.
2001: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Masaki Miyamoto; Shinji Tanaka; Masaharu Yoshihara; Koji Sumii; Fumio Shimamoto; Goro Kajiyama
B-cell monoclonality in Helicobacter pylori-associated chronic atrophic gastritis.
Virchows Archiv : an international journal of pathology 2001;438(3):232-7.
2001: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Masanori Ito; Hiroshi Masuda; Masaki Miyamoto; Shinji Tanaka; Masaharu Yoshihara; Koji Sumii; Fumio Shimamoto; Kazuaki Chayama
Microsatellite instability at D18S61 is associated with no regression of gastric mucosa-associated lymphoid tissue lymphoma after Helicobacter pylori eradication.
Oncology reports 2001;8(2):293-7.
2001: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Masanori Ito; Hiroshi Masuda; Masaki Miyamoto; Shinji Tanaka; Masaharu Yoshihara; Koji Sumii; Fumio Shimamoto; Kazuaki Chayama
c-myc gene mutation in gastric mucosa-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma.
Oncology reports 2001;8(2):289-92.
2001: Norimasa Matsutani; Hiroshi Yokozaki; E Tahara; Hidetoshi Tahara; Hiroki Kuniyasu; Yasuhiko Kitadai; Ken Haruma; Kazuaki Chayama; Eiichi Tahara; Wataru Yasui
Expression of MRE11 complex (MRE11, RAD50, NBS1) and hRap1 and its relation with telomere regulation, telomerase activity in human gastric carcinomas.
Pathobiology : journal of immunopathology, molecular and cellular biology 2001;69(4):219-24.
2001: Naohide Oue; Kazuhiro Sentani; Hiroshi Yokozaki; Yasuhiko Kitadai; Reiko Ito; Wataru Yasui
Promoter methylation status of the DNA repair genes hMLH1 and MGMT in gastric carcinoma and metaplastic mucosa.
Pathobiology : journal of immunopathology, molecular and cellular biology 2001;69(3):143-9.
2001: H Oh-e; Shinji Tanaka; Yasuhiko Kitadai; Fumio Shimamoto; Masaharu Yoshihara; Ken Haruma
Cathepsin D expression as a possible predictor of lymph node metastasis in submucosal colorectal cancer.
European journal of cancer (Oxford, England : 1990) 2001;37(2):180-8.
2000: T Shimizu; Shinji Tanaka; Ken Haruma; Yasuhiko Kitadai; Masaharu Yoshihara; Koji Sumii; Goro Kajiyama; Fumio Shimamoto
Growth characteristics of rectal carcinoid tumors.
Oncology 2000;59(3):229-37.
2000: Masaki Kunihiro; Shinji Tanaka; Ken Haruma; Yasuhiko Kitadai; Masaharu Yoshihara; Koji Sumii; Goro Kajiyama; M Nishiyama
Electrocautery snare resection stimulates cellular proliferation of residual colorectal tumor: an increasing gene expression related to tumor growth.
Diseases of the colon and rectum 2000;43(8):1107-15.
2000: Tomoari Kamada; Ken Haruma; E Miyoshi; M Mihara; Yasuhiko Kitadai; Masaharu Yoshihara; Koji Sumii; Goro Kajiyama; K Tahara; T Mukai; Yuzuru Kawamura; N Hattori
Cetraxate, a mucosal protective agent, combined with omeprazole, amoxycillin, and clarithromycin increases the eradication rate of helicobacter pylori in smokers.
Alimentary pharmacology & therapeutics 2000;14(8):1089-94.
2000: S Kido; Ken Haruma; Yasuhiko Kitadai; Masaharu Yoshihara; Koji Sumii; Goro Kajiyama; H Watanabe
Enhanced tumorigenicity of insulinoma by X-irradiation of the gastric regions in Sprague-Dawley male rats.
Journal of gastroenterology and hepatology 2000;15(7):766-70.
2000: Yasuhiko Kitadai; Ken Haruma; Naofumi Mukaida; Y Ohmoto; Norimasa Matsutani; Wataru Yasui; S Yamamoto; K Sumii; G Kajiyama; I J Fidler; Eiichi Tahara
Regulation of disease-progression genes in human gastric carcinoma cells by interleukin 8.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2735-40.
2000: Shinji Tanaka; Ken Haruma; H Oh-e; Shinji Nagata; Y Hirota; Akira Furudoi; Toru Amioka; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto
Conditions of curability after endoscopic resection for colorectal carcinoma with submucosally massive invasion.
Oncology reports 2000;7(4):783-8.
2000: Ken Haruma; K Komoto; Tomoari Kamada; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Koji Sumii; Goro Kajiyama
Helicobacter pylori infection is a major risk factor for gastric carcinoma in young patients.
Scandinavian journal of gastroenterology 2000;35(3):255-9.
2000: Shinji Tanaka; Ken Haruma; Masanori Ito; Shinji Nagata; H Oh-e; Y Hirota; Masaki Kunihiro; Yasuhiko Kitadai; M Yosihara; Koji Sumii; Goro Kajiyama
Detailed colonoscopy for detecting early superficial carcinoma: recent developments.
Journal of gastroenterology 2000;35 Suppl 12():121-5.
2000: S Yamamoto; Yasuhiko Kitadai; Akira Tsuchida; Tamito Sasaki; K Matsubara; Goro Kajiyama
Expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human gallbladder lesions.
European journal of cancer (Oxford, England : 1990) 2000;36(2):257-63.
1999: Yasuhiko Kitadai; Y Takahashi; K Haruma; K Naka; K Sumii; H Yokozaki; W Yasui; N Mukaida; Y Ohmoto; G Kajiyama; I J Fidler; Eiichi Tahara
Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice.
British journal of cancer 1999;81(4):647-53.
1999: Toru Hiyama; Hiroshi Yokozaki; Yasuhiko Kitadai; Ken Haruma; Wataru Yasui; Goro Kajiyama; E Tahara
Overexpression of human telomerase RNA is an early event in oesophageal carcinogenesis.
Virchows Archiv : an international journal of pathology 1999;434(6):483-7.
1999: T Goto; Ken Haruma; Yasuhiko Kitadai; M Ito; Masaharu Yoshihara; K Sumii; N Hayakawa; G Kajiyama
Enhanced expression of inducible nitric oxide synthase and nitrotyrosine in gastric mucosa of gastric cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(6):1411-5.
1998: T Hiyama; Hiroshi Yokozaki; Yasuhiko Kitadai; Eiichi Tahara; Hidetoshi Tahara; T Ide; K Haruma; Wataru Yasui; G Kajiyama; E Tahara
In situ mRNA hybridization technique for analysis of human telomerase RNA in gastric precancerous and cancerous lesions.
Japanese journal of cancer research : Gann 1998;89(11):1187-94.
1998: Yasuhiko Kitadai; Ken Haruma; T Tokutomi; Shinji Tanaka; K Sumii; M Carvalho; M Kuwabara; Kazuhiro Yoshida; T Hirai; G Kajiyama; Eiichi Tahara
Significance of vessel count and vascular endothelial growth factor in human esophageal carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(9):2195-200.
1998: S Yamamoto; K Fujii; Yasuhiko Kitadai; S Yamamoto; Akira Tsuchida; Goro Kajiyama
Expression of vascular endothelial growth factor in human gallbladder lesions.
Oncology reports 1998;5(5):1065-9.
1998: Masaharu Yoshihara; Koji Sumii; Ken Haruma; Kuninushi Kiyohira; N Hattori; Yasuhiko Kitadai; K Komoto; Shinji Tanaka; Goro Kajiyama
Correlation of ratio of serum pepsinogen I and II with prevalence of gastric cancer and adenoma in Japanese subjects.
The American journal of gastroenterology 1998;93(7):1090-6.
1998: Toru Hiyama; Hiroshi Yokozaki; Yasuhiko Kitadai; Hidetoshi Tahara; Wataru Yasui; Eiichi Tahara
[Analysis of expression of human telomerase RNA in gastric precancerous and cancerous lesions by using in situ mRNA hybridization].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(5):1190-3.
1998: Takahiro Ue; Hiroshi Yokozaki; Yasuhiko Kitadai; S Yamamoto; Wataru Yasui; Takenori Ishikawa; Eiichi Tahara
Co-expression of osteopontin and CD44v9 in gastric cancer.
International journal of cancer. Journal international du cancer 1998;79(2):127-32.
1998: Yasuhiko Kitadai; Ken Haruma; Koji Sumii; S Yamamoto; Takahiro Ue; Hiroshi Yokozaki; Wataru Yasui; Y Ohmoto; Goro Kajiyama; I J Fidler; Eiichi Tahara
Expression of interleukin-8 correlates with vascularity in human gastric carcinomas.
The American journal of pathology 1998;152(1):93-100.
1995: M Akagi; Hiroshi Yokozaki; Yasuhiko Kitadai; R Ito; Wataru Yasui; Ken Haruma; Goro Kajiyama; Eiichi Tahara
Expression of amphiregulin in human gastric cancer cell lines.
Cancer 1995;75(6 Suppl):1460-6.
1993: R Ito; Yasuhiko Kitadai; E Kyo; Hiroshi Yokozaki; Wataru Yasui; Uki Yamashita; H Nikai; Eiichi Tahara
Interleukin 1 alpha acts as an autocrine growth stimulator for human gastric carcinoma cells.
Cancer research 1993;53(17):4102-6.
1993: Hiroki Kuniyasu; Wataru Yasui; Hiroshi Yokozaki; Yasuhiko Kitadai; Eiichi Tahara
Aberrant expression of c-met mRNA in human gastric carcinomas.
International journal of cancer. Journal international du cancer 1993;55(1):72-5.
1993: Yasuhiko Kitadai; Wataru Yasui; Hiroshi Yokozaki; Hiroki Kuniyasu; A Ayhan; Ken Haruma; Goro Kajiyama; G R Johnson; Eiichi Tahara
Expression of amphiregulin, a novel gene of the epidermal growth factor family, in human gastric carcinomas.
Japanese journal of cancer research : Gann 1993;84(8):879-84.
1993: H Tohdo; Ken Haruma; Yasuhiko Kitadai; Masaharu Yoshihara; T Shimamoto; Koji Sumii; Goro Kajiyama
Gastric emptying and bezoars in Japanese. Report of five cases.
Digestive diseases and sciences 1993;38(8):1422-5.
1993: Wataru Yasui; T Sano; K Nishimura; Yasuhiko Kitadai; Z Q Ji; Hiroshi Yokozaki; H Ito; Eiichi Tahara
Expression of P-cadherin in gastric carcinomas and its reduction in tumor progression.
International journal of cancer. Journal international du cancer 1993;54(1):49-52.
1993: Yasuhiko Kitadai; H Yamazaki; Wataru Yasui; E Kyo; Hiroshi Yokozaki; Goro Kajiyama; A C Johnson; Ira Pastan; Eiichi Tahara
GC factor represses transcription of several growth factor/receptor genes and causes growth inhibition of human gastric carcinoma cell lines.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(4):291-6.
1993: Wataru Yasui; A Ayhan; Yasuhiko Kitadai; K Nishimura; Hiroshi Yokozaki; H Ito; Eiichi Tahara
Increased expression of p34cdc2 and its kinase activity in human gastric and colonic carcinomas.
International journal of cancer. Journal international du cancer 1993;53(1):36-41.
1993: K Yoshida; Hiroki Kuniyasu; Wataru Yasui; Yasuhiko Kitadai; T Toge; Eiichi Tahara
Expression of growth factors and their receptors in human esophageal carcinomas: regulation of expression by epidermal growth factor and transforming growth factor alpha.
Journal of cancer research and clinical oncology 1993;119(7):401-7.
1993: A Ayhan; Wataru Yasui; Hiroshi Yokozaki; Yasuhiko Kitadai; Eiichi Tahara
Reduced expression of nm23 protein is associated with advanced tumor stage and distant metastases in human colorectal carcinomas.
Virchows Archiv. B, Cell pathology including molecular pathology 1993;63(4):213-8.
1992: Yasuhiko Kitadai; Wataru Yasui; Hiroshi Yokozaki; Hiroki Kuniyasu; Ken Haruma; Goro Kajiyama; Eiichi Tahara
The level of a transcription factor Sp1 is correlated with the expression of EGF receptor in human gastric carcinomas.
Biochemical and biophysical research communications 1992;189(3):1342-8.
1992: Hiroki Kuniyasu; Wataru Yasui; Yasuhiko Kitadai; Hiroshi Yokozaki; H Ito; Eiichi Tahara
Frequent amplification of the c-met gene in scirrhous type stomach cancer.
Biochemical and biophysical research communications 1992;189(1):227-32.
1992: H Yokozaki; Hiroki Kuniyasu; Yasuhiko Kitadai; K Nishimura; H Todo; A Ayhan; Wataru Yasui; H Ito; Eiichi Tahara
p53 point mutations in primary human gastric carcinomas.
Journal of cancer research and clinical oncology 1992;119(2):67-70.
1991: N Takekura; Wataru Yasui; E Kyo; K Yoshida; T Kameda; Yasuhiko Kitadai; K Abe; K Umezawa; Eiichi Tahara
Effects of tyrosine kinase inhibitor, erbstatin, on cell growth and growth-factor/receptor gene expression in human gastric carcinoma cells.
International journal of cancer. Journal international du cancer 1991;47(6):938-42.