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Jan Kitajewski

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Aino Murtomaki; Minji K Uh; Valeriya Borisenko; Yun K Choi; Christopher Kitajewski; Jan Kitajewski; Carrie J Shawber
Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium.
Jan Kitajewski
Wnts heal by restraining angiogenesis.
Claire Reeves; Pelisa Charles-Horvath; Jan Kitajewski
Studies in mice reveal a role for anthrax toxin receptors in matrix metalloproteinase function and extracellular matrix homeostasis.

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2013: Aino Murtomaki; Minji K Uh; Valeriya Borisenko; Yun K Choi; Christopher Kitajewski; Jan Kitajewski; Carrie J Shawber
Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium.
Development (Cambridge, England) 2013;140(11):2365-76.
2013: Jan Kitajewski
Wnts heal by restraining angiogenesis.
Blood 2013;121(13):2381-2.
2013: Claire Reeves; Pelisa Charles-Horvath; Jan Kitajewski
Studies in mice reveal a role for anthrax toxin receptors in matrix metalloproteinase function and extracellular matrix homeostasis.
Toxins 2013;5(2):315-26.
2013: Minji K Uh; Jessica Kandel; Jan Kitajewski
Evaluating tumor angiogenesis.
Methods in molecular biology (Clifton, N.J.) 2013;980():341-51.
2012: Haixia Xu; Baohong Zhao; Jimmy Zhu; Carl P Blobel; Allen Y Chung; Julia Foldi; Lionel B Ivashkiv; Jan Kitajewski; Yueming Li; Hasina Outtz; Keiko Ozato; Paul Saftig; Chao Shi; Sinead Smith; Silvio Weber; Xiaoyu Hu
Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.
Nature immunology 2012;13(7):642-50.
2012: Jennifer J Tung; Ian W Tattersall; Jan Kitajewski
Tips, stalks, tubes: notch-mediated cell fate determination and mechanisms of tubulogenesis during angiogenesis.
Cold Spring Harbor perspectives in medicine 2012;2(2):a006601.
2012: Jan Kitajewski
Arteriovenous malformations in five dimensions.
Science translational medicine 2012;4(117):117fs3.
2012: Michael Quante; Anil K Rustgi; Carrie Shawber; Julian A Abrams; Samuel Asfaha; Govind Bhagat; Zinaida Dubeykovskaya; Jose-Luiz Figueiredo; Richard Friedman; Pamela Good; Jan Kitajewski; Michele D Lee; Yoomi Lee; Charles J Lightdale; Umar Mahmood; Frederic Marache; Timothy C Wang
Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia.
Cancer cell 2012;21(1):36-51.
2012: Jan Kitajewski
"Large eaters" meet blood vessels: a new thematic series on macrophages and angiogenesis.
Vascular cell 2012;4(1):17.
2011: Natalie M Kofler; Hasina Outtz Reed; Carrie J Shawber; Josephine Galatioto; Thaned Kangsamaksin; Jan Kitajewski
Notch signaling in developmental and tumor angiogenesis.
Genes & cancer 2011;2(12):1106-16.
2011: Jan Kitajewski
Endothelial laminins underlie the tip cell microenvironment.
EMBO reports 2011;12(11):1087-8.
2011: Elisa Boscolo; Jennifer T Durham; Shoshana Greenberger; Ira M Herman; Jan Kitajewski; John B Mulliken; Camille L Stewart; June K Wu; Joyce Bischoff
JAGGED1 signaling regulates hemangioma stem cell-to-pericyte/vascular smooth muscle cell differentiation.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(10):2181-92.
2011: Hasina H Outtz; Nicole Steinbach; Ian W Tattersall; Natalie M Kofler; Jan Kitajewski
Notch1 controls macrophage recruitment and Notch signaling is activated at sites of endothelial cell anastomosis during retinal angiogenesis in mice.
Blood 2011;118(12):3436-9.
2011: Utpal B Pajvani; Varman T Samuel; Carrie J Shawber; Gerald I Shulman; Andreas L Birkenfeld; Jan Kitajewski; Domenico Accili
Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner.
Nature medicine 2011;17(8):961-7.
2011: Nathan M Hunkapiller; Mirhan Kapidzic; Jan Kitajewski; Emin Maltepe; Vicki Plaks; Jay C Cross; Malgorzata Gasperowicz; Susan J Fisher
A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia.
Development (Cambridge, England) 2011;138(14):2987-98.
2011: Jan Kitajewski
Fine-tuning endothelial Notch: SIRT-ainly an unexpected mechanism.
Developmental cell 2011;20(5):577-8.
2011: Omotinuwe Adepoju; Joyce Bischoff; Elisa Boscolo; Alex Kitajewski; Jan Kitajewski; Karen Tong; Alvin Wong; June K Wu
Expression of HES and HEY genes in infantile hemangiomas.
Vascular cell 2011;3():19.
2011: Yasuhiro Funahashi; Carrie J Shawber; Anshula Sharma; Emi Kanamaru; Yun K Choi; Jan Kitajewski
Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity.
Vascular cell 2011;3(1):2.
2011: Jan Kitajewski; Yihai Cao; Mark Slevin
It's hard to keep all things angiogenic in one JAR!
Vascular cell 2011;3(1):1.
2010: Donna Nichol; Carrie Shawber; Michael J Fitch; Kathryn Bambino; Anshula Sharma; Jan Kitajewski; Heidi Stuhlmann
Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7.
Blood 2010;116(26):6133-43.
2010: Julia Foldi; Allen Y Chung; Haixia Xu; Jimmy Zhu; Hasina H Outtz; Jan Kitajewski; Yueming Li; Xiaoyu Hu; Lionel B Ivashkiv
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5023-31.
2010: Hasina Hamilton Outtz; June K Wu; Xing Wang; Jan Kitajewski
Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(7):4363-73.
2010: Young-Han Park; Su Jin Kim; Byung-Hoon Jeong; Thomas J Herzog; Jason Wright; Jan Kitajewski; Chae Chun Rhim; Pong Rheem Jang; Jung Bae Kang; Sung Ju Kim
Follicular stimulating hormone enhances Notch 1 expression in SK-OV-3 ovarian cancer cells.
Journal of gynecologic oncology 2010;21(2):119-24.
2010: Jason M Butler; Daniel J Nolan; Eva L Vertes; Barbara Varnum-Finney; Hideki Kobayashi; Andrea T Hooper; Seandel Marco; Koji Shido; Ian A White; Mariko Kobayashi; Larry Witte; Chad May; Carrie Shawber; Yuki Kimura; Jan Kitajewski; Zev Rosenwaks; Irwin D Bernstein; Shahin Rafii
Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.
Cell stem cell 2010;6(3):251-64.
2010: June K Wu; Omotinuwe Adepoju; Dinuka De Silva; Keith Baribault; Elisa Boscolo; Joyce Bischoff; Jan Kitajewski
A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.
Angiogenesis 2010;13(1):15-23.
2010: C V Reeves; J Dufraine; J A T Young; Jan Kitajewski
Anthrax toxin receptor 2 is expressed in murine and tumor vasculature and functions in endothelial proliferation and morphogenesis.
Oncogene 2010;29(6):789-801.
2010: Jennifer J Tung; Jan Kitajewski
Chloride intracellular channel 1 functions in endothelial cell growth and migration.
Journal of angiogenesis research 2010;2():23.
2010: Yasuhiro Funahashi; Carrie J Shawber; Marina Vorontchikhina; Anshula Sharma; Hasina H Outtz; Jan Kitajewski
Notch regulates the angiogenic response via induction of VEGFR-1.
Journal of angiogenesis research 2010;2(1):3.
2009: Nataki C Douglas; Hongyan Tang; Raul Gomez; Bronislaw Pytowski; Daniel J Hicklin; Christopher M Sauer; Jan Kitajewski; Mark V Sauer; Ralf C Zimmermann
Vascular endothelial growth factor receptor 2 (VEGFR-2) functions to promote uterine decidual angiogenesis during early pregnancy in the mouse.
Endocrinology 2009;150(8):3845-54.
2009: June K Wu; Jan Kitajewski
A potential role for notch signaling in the pathogenesis and regulation of hemangiomas.
The Journal of craniofacial surgery 2009;20 Suppl 1():698-702.
2009: Benjamin Kleaveland; Xiangjian Zheng; Jian J Liu; Yannick Blum; Jennifer J Tung; Zhiying Zou; Shawn M Sweeney; Mei Chen; Lili Guo; Min Min Lu; Diane Zhou; Jan Kitajewski; Markus Affolter; Mark H Ginsberg; Mark L Kahn
Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway.
Nature medicine 2009;15(2):169-76.
2009: Mark Slevin; Yihai Cao; Jan Kitajewski
Welcome to Journal of Angiogenesis Research.
Journal of angiogenesis research 2009;1():1.
2009: Jennifer J Tung; Oliver Hobert; Mark Berryman; Jan Kitajewski
Chloride intracellular channel 4 is involved in endothelial proliferation and morphogenesis in vitro.
Angiogenesis 2009;12(3):209-20.
2008: Nancy L Parmalee; Jan Kitajewski
Wnt signaling in angiogenesis.
Current drug targets 2008;9(7):558-64.
2008: Yasuhiro Funahashi; Sonia L Hernandez; Indranil Das; Audrey Ahn; Jianzhong Huang; Marina Vorontchikhina; Anshula Sharma; Emi Kanamaru; Valeriya Borisenko; Dinuka M Desilva; Akihiko Suzuki; Xing Wang; Carrie J Shawber; Jessica J Kandel; Darrell J Yamashiro; Jan Kitajewski
A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis.
Cancer research 2008;68(12):4727-35.
2008: Marielba Zerlin; Martin A Julius; Jan Kitajewski
Wnt/Frizzled signaling in angiogenesis.
Angiogenesis 2008;11(1):63-9.
2007: Carrie J Shawber; Yasuhiro Funahashi; Esther Francisco; Marina Vorontchikhina; Yukari Kitamura; Stephanie A Stowell; Valeriya Borisenko; Nikki Feirt; Simona Podgrabinska; Kazuko Shiraishi; Kallayanee Chawengsaksophak; Janet Rossant; Domenico Accili; Mihaela Skobe; Jan Kitajewski
Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.
The Journal of clinical investigation 2007;117(11):3369-82.
2007: Tadahiro Kitamura; Yukari Ido Kitamura; Yasuhiro Funahashi; Carrie J Shawber; Diego H Castrillon; Ramya Kollipara; Ronald A DePinho; Jan Kitajewski; Domenico Accili
A Foxo/Notch pathway controls myogenic differentiation and fiber type specification.
The Journal of clinical investigation 2007;117(9):2477-85.
2007: Kai M Schmidt-Ott; T Nestor H Masckauchan; Xia Chen; Benjamin J Hirsh; Abby Sarkar; Jun Yang; Neal Paragas; Valerie A Wallace; Daniel Dufort; Paul Pavlidis; Bernd Jagla; Jan Kitajewski; Jonathan Barasch
beta-catenin/TCF/Lef controls a differentiation-associated transcriptional program in renal epithelial progenitors.
Development (Cambridge, England) 2007;134(17):3177-90.
2007: Stephanie A Stowell; Jan Kitajewski
Hey, there's a hole in my heart.
Circulation research 2007;100(6):764-5.
2007: Anne M Goodwin; Jan Kitajewski; Patricia A D'Amore
Wnt1 and Wnt5a affect endothelial proliferation and capillary length; Wnt2 does not.
Growth factors (Chur, Switzerland) 2007;25(1):25-32.
2006: T Néstor H Masckauchán; Dritan Agalliu; Marina Vorontchikhina; Audrey Ahn; Nancy L Parmalee; Chi-Ming Li; Alan Khoo; Benjamin Tycko; Anthony M C Brown; Jan Kitajewski
Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2.
Molecular biology of the cell 2006;17(12):5163-72.
2006: Tatiana Kisseleva; Li Song; Marina Vorontchikhina; Nikki Feirt; Jan Kitajewski; Christian Schindler
NF-kappaB regulation of endothelial cell function during LPS-induced toxemia and cancer.
The Journal of clinical investigation 2006;116(11):2955-63.
2006: Pontus Holm; Francisco J Rodríguez; Julianna Kele; Gonçalo Castelo-Branco; Jan Kitajewski; Ernest Arenas
BMPs, FGF8 and Wnts regulate the differentiation of locus coeruleus noradrenergic neuronal precursors.
Journal of neurochemistry 2006;99(1):343-52.
2006: X Yang; Min-Wei Chen; stephane terry; Francis Vacherot; Debra L Bemis; Jillian L Capodice; Jan Kitajewski; Alexandre de la Taille; Mitchell C Benson; Y Guo; Ralph Buttyan
Complex regulation of human androgen receptor expression by Wnt signaling in prostate cancer cells.
Oncogene 2006;25(24):3436-44.
2006: T Néstor H Masckauchán; Jan Kitajewski
Wnt/Frizzled signaling in the vasculature: new angiogenic factors in sight.
Physiology (Bethesda, Md.) 2006;21():181-8.
2006: Bach-Cuc Nguyen; Karine Lefort; Anna Mandinova; Dario Antonini; Vikram Devgan; Giusy Della Gatta; Maranke I Koster; Zhuo Zhang; Jian Wang; Alice Tommasi di Vignano; Jan Kitajewski; giovanna chiorino; Dennis R Roop; Caterina Missero; G Paolo Dotto
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation.
Genes & development 2006;20(8):1028-42.
2005: Qinghua Zeng; Shenglin Li; Douglas B Chepeha; Thomas J Giordano; Jong Li; Honglai Zhang; Peter J Polverini; Jacques E Nor; Jan Kitajewski; Cun-Yu Wang
Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling.
Cancer cell 2005;8(1):13-23.
2005: Xuezhen Yang; Min-Wei Chen; stephane terry; Francis Vacherot; Dominique K Chopin; Debra L Bemis; Jan Kitajewski; Mitchell C Benson; Yinglu Guo; Ralph Buttyan
A human- and male-specific protocadherin that acts through the wnt signaling pathway to induce neuroendocrine transdifferentiation of prostate cancer cells.
Cancer research 2005;65(12):5263-71.
2005: Marina Vorontchikhina; Ralf C Zimmermann; Carrie J Shawber; Hongyan Tang; Jan Kitajewski
Unique patterns of Notch1, Notch4 and Jagged1 expression in ovarian vessels during folliculogenesis and corpus luteum formation.
Gene expression patterns : GEP 2005;5(5):701-9.
2005: Samuel A Pauli; Hongyan Tang; Jeff Wang; Peter Bohlen; Robert Posser; Tipton Hartman; Mark V Sauer; Jan Kitajewski; Ralf C Zimmermann
The vascular endothelial growth factor (VEGF)/VEGF receptor 2 pathway is critical for blood vessel survival in corpora lutea of pregnancy in the rodent.
Endocrinology 2005;146(3):1301-11.
2005: Gary S Nakhuda; Ralf C Zimmermann; Peter Bohlen; Fang Liao; Mark V Sauer; Jan Kitajewski
Inhibition of the vascular endothelial cell (VE)-specific adhesion molecule VE-cadherin blocks gonadotropin-dependent folliculogenesis and corpus luteum formation and angiogenesis.
Endocrinology 2005;146(3):1053-9.
2005: Randy S Levinson; Ekatherina Batourina; Christopher Choi; Marina Vorontchikhina; Jan Kitajewski; Cathy L Mendelsohn
Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development.
Development (Cambridge, England) 2005;132(3):529-39.
2005: T Néstor H Masckauchán; Carrie J Shawber; Yasuhiro Funahashi; Chi-Ming Li; Jan Kitajewski
Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells.
Angiogenesis 2005;8(1):43-51.
2004: Katerina Politi; Nikki Feirt; Jan Kitajewski
Notch in mammary gland development and breast cancer.
Seminars in cancer biology 2004;14(5):341-7.
2004: Liang You; Biao He; Zhidong Xu; Kazutsugu Uematsu; Julien Mazieres; Iwao Mikami; Noemi Reguart; Terry W Moody; Jan Kitajewski; Frank McCormick; David M Jablons
Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells.
Oncogene 2004;23(36):6170-4.
2004: Indranil Das; Colleen Craig; Yasuhiro Funahashi; Kwang-Mook Jung; TAE-WAN KIM; Richard Byers; Andrew P Weng; Jeffery L Kutok; Jon C Aster; Jan Kitajewski
Notch oncoproteins depend on gamma-secretase/presenilin activity for processing and function.
The Journal of biological chemistry 2004;279(29):30771-80.
2004: Jozef Spychala; Jan Kitajewski
Wnt and beta-catenin signaling target the expression of ecto-5'-nucleotidase and increase extracellular adenosine generation.
Experimental cell research 2004;296(2):99-108.
2004: Mathias Mericskay; Jan Kitajewski; David Sassoon
Wnt5a is required for proper epithelial-mesenchymal interactions in the uterus.
Development (Cambridge, England) 2004;131(9):2061-72.
2004: Carrie J Shawber; Jan Kitajewski
Notch function in the vasculature: insights from zebrafish, mouse and man.
BioEssays : news and reviews in molecular, cellular and developmental biology 2004;26(3):225-34.
2003: Gonçalo Castelo-Branco; Joseph Wagner; Francisco J Rodriguez; Julianna Kele; Kyle M Sousa; Nina Rawal; H Amalia Pasolli; Elaine Fuchs; Jan Kitajewski; Ernest Arenas
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12747-52.
2003: C S H Young; T N H Masckauchan; Jan Kitajewski
Beta-catenin/Tcf activation partially mimics the transforming activity of Wnt-1 in Rat-1 fibroblasts.
Differentiation; research in biological diversity 2003;71(8):477-85.
2003: Tatsuo Ohira; Robert M Gemmill; Kevin Ferguson; Sophie Kusy; Joelle Roche; Elisabeth Brambilla; Chan Zeng; Anna Baron; Lynne Bemis; Paul F Erickson; Elizabeth Wilder; Anil Rustgi; Jan Kitajewski; Edward Gabrielson; Roy M Bremnes; Wilbur Franklin; Harry A Drabkin
WNT7a induces E-cadherin in lung cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10429-34.
2003: Ralf C Zimmermann; Tipton Hartman; Suzanne Kavic; Samuel A Pauli; Peter Bohlen; Mark V Sauer; Jan Kitajewski
Vascular endothelial growth factor receptor 2-mediated angiogenesis is essential for gonadotropin-dependent follicle development.
The Journal of clinical investigation 2003;112(5):659-69.
2003: Carrie J Shawber; Indranil Das; Esther Francisco; Jan Kitajewski
Notch signaling in primary endothelial cells.
Annals of the New York Academy of Sciences 2003;995():162-70.
2002: Axelle Cadoret; Christine Ovejero; Benoit Terris; Evelyne Souil; Laurence Lévy; Wouter H Lamers; Jan Kitajewski; Axel Kahn; Christine Perret
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism.
Oncogene 2002;21(54):8293-301.
2002: Slava Chtarbova; Inko Nimmrich; Silke Erdmann; Peter Herter; Matthias Renner; Jan Kitajewski; Oliver Müller
Murine Nr4a1 and Herpud1 are up-regulated by Wnt-1, but the homologous human genes are independent from beta-catenin activation.
The Biochemical journal 2002;367(Pt 3):723-8.
2002: Takatoshi Karasawa; Hisayuki Yokokura; Jan Kitajewski; Paul J Lombroso
Frizzled-9 is activated by Wnt-2 and functions in Wnt/beta -catenin signaling.
The Journal of biological chemistry 2002;277(40):37479-86.
2002: Zongbing You; Daniel Saims; Shaoqiong Chen; Zhaocheng Zhang; Denis C Guttridge; Kun-Liang Guan; Ormond A MacDougald; Anthony M C Brown; Gerard Evan; Jan Kitajewski; Cun-Yu Wang
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis.
The Journal of cell biology 2002;157(3):429-40.
2001: G Wu; Svetlana Lyapina; Indranil Das; Jianze Li; ME Gurney; A Pauley; I Chui; Raymond J Deshaies; Jan Kitajewski
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation.
Molecular and cellular biology 2001;21(21):7403-15.
2001: Ralf C Zimmermann; Tipton Hartman; Peter Bohlen; Mark V Sauer; Jan Kitajewski
Preovulatory treatment of mice with anti-VEGF receptor 2 antibody inhibits angiogenesis in corpora lutea.
Microvascular research 2001;62(1):15-25.
2001: Hendrik Uyttendaele; J Ho; Janet Rossant; Jan Kitajewski
Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5643-8.
2001: Ralf C Zimmermann; Ennian Xiao; N Husami; Mark V Sauer; Rogerio A Lobo; Jan Kitajewski; Michel Ferin
Short-term administration of antivascular endothelial growth factor antibody in the late follicular phase delays follicular development in the rhesus monkey.
The Journal of clinical endocrinology and metabolism 2001;86(2):768-72.
2001: Shiming Chen; Denis C Guttridge; Zongbing You; Zhaocheng Zhang; Andrew Fribley; Marty W Mayo; Jan Kitajewski; Cun-Yu Wang
Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription.
The Journal of cell biology 2001;152(1):87-96.
2000: MA Julius; B Schelbert; W Hsu; E Fitzpatrick; Eek-Hoon Jho; François Fagotto; Frank Costantini; Jan Kitajewski
Domains of axin and disheveled required for interaction and function in wnt signaling.
Biochemical and biophysical research communications 2000;276(3):1162-9.
2000: Jan Kitajewski; David Sassoon
The emergence of molecular gynecology: homeobox and Wnt genes in the female reproductive tract.
BioEssays : news and reviews in molecular, cellular and developmental biology 2000;22(10):902-10.
2000: Hendrik Uyttendaele; V Closson; G Wu; F Roux; G Weinmaster; Jan Kitajewski
Notch4 and Jagged-1 induce microvessel differentiation of rat brain endothelial cells.
Microvascular research 2000;60(2):91-103.
2000: Luke T Krebs; Yingzi Xue; Christine R Norton; John R Shutter; M Maguire; John P Sundberg; D Gallahan; V Closson; Jan Kitajewski; Robert Callahan; Gilbert H Smith; Kevin L Stark; Thomas Gridley
Notch signaling is essential for vascular morphogenesis in mice.
Genes & development 2000;14(11):1343-52.
2000: John R Shutter; S Scully; W Fan; W G Richards; Jan Kitajewski; G A Deblandre; Chris Kintner; Kevin L Stark
Dll4, a novel Notch ligand expressed in arterial endothelium.
Genes & development 2000;14(11):1313-8.
2000: Jesus V Soriano; Hendrik Uyttendaele; Jan Kitajewski; Roberto Montesano
Expression of an activated Notch4(int-3) oncoprotein disrupts morphogenesis and induces an invasive phenotype in mammary epithelial cells in vitro.
International journal of cancer. Journal international du cancer 2000;86(5):652-9.
2000: MA Julius; Q Yan; Z Zheng; Jan Kitajewski
Q vectors, bicistronic retroviral vectors for gene transfer.
BioTechniques 2000;28(4):702-8.
2000: Jesus V Soriano; Irmgard Irminger-Finger; Hendrik Uyttendaele; G Vaudan; Jan Kitajewski; André-Pascal Sappino; Roberto Montesano
Repression of the putative tumor suppressor gene Bard1 or expression of Notch4(int-3) oncogene subvert the morphogenetic properties of mammary epithelial cells.
Advances in experimental medicine and biology 2000;480():175-84.
1999: MA Julius; S D Rai; Jan Kitajewski
Chimeric Wnt proteins define the amino-terminus of Wnt-1 as a transformation-specific determinant.
Oncogene 1999;18(1):149-56.
1998: G Wu; E J Hubbard; Jan Kitajewski; Iva Greenwald
Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15787-91.
1998: C S H Young; M Kitamura; S Hardy; Jan Kitajewski
Wnt-1 induces growth, cytosolic beta-catenin, and Tcf/Lef transcriptional activation in Rat-1 fibroblasts.
Molecular and cellular biology 1998;18(5):2474-85.
1998: Hendrik Uyttendaele; Jesus V Soriano; Roberto Montesano; Jan Kitajewski
Notch4 and Wnt-1 proteins function to regulate branching morphogenesis of mammary epithelial cells in an opposing fashion.
Developmental biology 1998;196(2):204-17.
1997: H Shimizu; MA Julius; M Giarré; Z Zheng; A M Brown; Jan Kitajewski
Transformation by Wnt family proteins correlates with regulation of beta-catenin.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(12):1349-58.
1997: E J Hubbard; G Wu; Jan Kitajewski; Iva Greenwald
sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins.
Genes & development 1997;11(23):3182-93.
1997: K Lin; Shulin Wang; MA Julius; Jan Kitajewski; M Moos; Frank P Luyten
The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11196-200.
1996: H Uyttendaele; Giovanna Marazzi; G Wu; Q Yan; D Sassoon; Jan Kitajewski
Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene.
Development (Cambridge, England) 1996;122(7):2251-9.