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Ken Kitajima

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Mari Akasaka; Koichi H Kato; Ken Kitajima; Hitoshi Sawada
Identification of novel isoforms of vitellogenin expressed in ascidian eggs.
Chihiro Sato; Ken Kitajima
Impact of structural aberrancy of polysialic acid and its synthetic enzyme ST8SIA2 in schizophrenia.
Waraporn Kasekarn; Estelle Garénaux; Kazuki Hori; Takeru Kanazawa; Kessiri Kongmanas; Xue Lian; Chihiro Sato; Nongnuj Tanphaichitr; Tomoyuki Tsuchiyama; Hiroshi Yasue; Ken Kitajima
Pig sperm membrane microdomains contain a highly glycosylated 15-25-kDa wheat germ agglutinin-binding protein.

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All Publications

2013: Mari Akasaka; Koichi H Kato; Ken Kitajima; Hitoshi Sawada
Identification of novel isoforms of vitellogenin expressed in ascidian eggs.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2013;320(2):118-28.
2013: Chihiro Sato; Ken Kitajima
Impact of structural aberrancy of polysialic acid and its synthetic enzyme ST8SIA2 in schizophrenia.
Frontiers in cellular neuroscience 2013;7():61.
2012: Waraporn Kasekarn; Estelle Garénaux; Kazuki Hori; Takeru Kanazawa; Kessiri Kongmanas; Xue Lian; Chihiro Sato; Nongnuj Tanphaichitr; Tomoyuki Tsuchiyama; Hiroshi Yasue; Ken Kitajima
Pig sperm membrane microdomains contain a highly glycosylated 15-25-kDa wheat germ agglutinin-binding protein.
Biochemical and biophysical research communications 2012;426(3):356-62.
2012: Sayaka Ono; Masaya Hane; Ken Kitajima; Chihiro Sato
Novel regulation of fibroblast growth factor 2 (FGF2)-mediated cell growth by polysialic acid.
The Journal of biological chemistry 2012;287(6):3710-22.
2011: Shinji Miyata; Chihiro Sato; Masaru Toriyama; Nao Yamakawa; Ken Kitajima
Co-expression of two distinct polysialic acids, α2,8- and α2,9-linked polymers of N-acetylneuraminic acid, in distinct glycoproteins and glycolipids in sea urchin sperm.
Glycobiology 2011;21(12):1596-605.
2011: Chihiro Sato; Ken Kitajima
[New function of polysialic acid and its involvement in neural activities].
Seikagaku. The Journal of Japanese Biochemical Society 2011;83(3):189-96.
2011: Sadako Inoue; Ken Kitajima; Chihiro Sato; Shinji Go
Human KDN (deaminated neuraminic acid) and its elevated expression in cancer cells: mechanism and significance.
Advances in experimental medicine and biology 2011;705():669-78.
2010: Emi Inoko; Yuji Nishiura; Hiroshi Tanaka; Takashi Takahashi; Koichi Furukawa; Ken Kitajima; Chihiro Sato
Developmental stage-dependent expression of an alpha2,8-trisialic acid unit on glycoproteins in mouse brain.
Glycobiology 2010;20(7):916-28.
2010: Sadako Inoue; Chihiro Sato; Ken Kitajima
Extensive enrichment of N-glycolylneuraminic acid in extracellular sialoglycoproteins abundantly synthesized and secreted by human cancer cells.
Glycobiology 2010;20(6):752-62.
2009: Yukihiro Kanato; Sayaka Ono; Ken Kitajima; Chihiro Sato
Complex formation of a brain-derived neurotrophic factor and glycosaminoglycans.
Bioscience, biotechnology, and biochemistry 2009;73(12):2735-41.
2009: Tomoko Adachi; Chihiro Sato; Yasunori Kishi; Kazuhide Totani; Takeomi Murata; Taichi Usui; Ken Kitajima
Membrane microdomains from early gastrula embryos of medaka, Oryzias latipes, are a platform of E-cadherin- and carbohydrate-mediated cell-cell interactions during epiboly.
Glycoconjugate journal 2009;26(3):285-99.
2008: Yukihiro Kanato; Ken Kitajima; Chihiro Sato
Direct binding of polysialic acid to a brain-derived neurotrophic factor depends on the degree of polymerization.
Glycobiology 2008;18(12):1044-53.
2007: Nao Yamakawa; Chihiro Sato; Shinji Miyata; Eri Maehashi; Masaru Toriyama; Noriko Sato; Kimio Furuhata; Ken Kitajima
Development of sensitive chemical and immunochemical methods for detecting sulfated sialic acids and their application to glycoconjugates from sea urchin sperm and eggs.
Biochimie 2007;89(11):1396-408.
2007: Joe Tiralongo; Akiko Fujita; Chihiro Sato; Ken Kitajima; Friederike Lehmann; Melanie Oschlies; Rita Gerardy-Schahn; Anja K Münster-Kühnel
The rainbow trout CMP-sialic acid synthetase utilises a nuclear localization signal different from that identified in the mouse enzyme.
Glycobiology 2007;17(9):945-54.
2007: Tomoko Adachi; Chihiro Sato; Ken Kitajima
Membrane microdomain formation is crucial in epiboly during gastrulation of medaka.
Biochemical and biophysical research communications 2007;358(3):848-53.
2007: Shinji Go; Chihiro Sato; Jun Yin; Reiji Kannagi; Ken Kitajima
Hypoxia-enhanced expression of free deaminoneuraminic acid in human cancer cells.
Biochemical and biophysical research communications 2007;357(2):537-42.
2007: Akiko Fujita; Chihiro Sato; Ken Kitajima
Identification of the nuclear export signals that regulate the intracellular localization of the mouse CMP-sialic acid synthetase.
Biochemical and biophysical research communications 2007;355(1):174-80.
2007: Zenta Yasukawa; Chihiro Sato; Ken Kitajima
Identification of an inflammation-inducible serum protein recognized by anti-disialic acid antibodies as carbonic anhydrase II.
Journal of biochemistry 2007;141(3):429-41.
2007: Yoichiro Harada; Chihiro Sato; Ken Kitajima
Complex formation of 70-kDa heat shock protein with acidic glycolipids and phospholipids.
Biochemical and biophysical research communications 2007;353(3):655-60.
2006: Shinji Miyata; Chihiro Sato; Hironobu Kumita; Masaru Toriyama; Victor D Vacquier; Ken Kitajima
Flagellasialin: a novel sulfated alpha2,9-linked polysialic acid glycoprotein of sea urchin sperm flagella.
Glycobiology 2006;16(12):1229-41.
2006: Shinji Asahina; Chihiro Sato; Midori Matsuno; Tsukasa Matsuda; Karen J Colley; Ken Kitajima
Involvement of the alpha2,8-polysialyltransferases II/STX and IV/PST in the biosynthesis of polysialic acid chains on the O-linked glycoproteins in rainbow trout ovary.
Journal of biochemistry 2006;140(5):687-701.
2006: Shinji Go; Chihiro Sato; Kimio Furuhata; Ken Kitajima
Oral ingestion of mannose alters the expression level of deaminoneuraminic acid (KDN) in mouse organs.
Glycoconjugate journal 2006;23(5-6):411-21.
2006: Sadako Inoue; Ken Kitajima
KDN (deaminated neuraminic acid): dreamful past and exciting future of the newest member of the sialic acid family.
Glycoconjugate journal 2006;23(5-6):277-90.
2006: Ken Kitajima; Kay-Hooi Khoo; Senitiroh Hakomori
Introduction. Professor Yasuo Inoue: 1934-2005.
Glycoconjugate journal 2006;23(5-6):273-6.
2006: Zenta Yasukawa; Chihiro Sato; Kotone Sano; Haruko Ogawa; Ken Kitajima
Identification of disialic acid-containing glycoproteins in mouse serum: a novel modification of immunoglobulin light chains, vitronectin, and plasminogen.
Glycobiology 2006;16(7):651-65.
2005: Zenta Yasukawa; Chihiro Sato; Ken Kitajima
Inflammation-dependent changes in alpha2,3-, alpha2,6-, and alpha2,8-sialic acid glycotopes on serum glycoproteins in mice.
Glycobiology 2005;15(9):827-37.
2005: Thomas Haselhorst; Anja K Münster-Kühnel; Anita Stolz; Melanie Oschlies; Joe Tiralongo; Ken Kitajima; Rita Gerardy-Schahn; Mark von Itzstein
Probing a CMP-Kdn synthetase by 1H, 31P, and STD NMR spectroscopy.
Biochemical and biophysical research communications 2005;327(2):565-70.
2005: Akiko Fujita; Chihiro Sato; Anja K Münster-Kühnel; Rita Gerardy-Schahn; Ken Kitajima
Development of a simple and efficient method for assaying cytidine monophosphate sialic acid synthetase activity using an enzymatic reduced nicotinamide adenine dinucleotide/oxidized nicotinamide adenine dinucleotide converting system.
Analytical biochemistry 2005;337(1):12-21.
2004: Hiroki Okumura; Yoshinori Kohno; Yuki Iwata; Hitoshi Mori; Naohito Aoki; Chihiro Sato; Ken Kitajima; Daita Nadano; Tsukasa Matsuda
A newly identified zona pellucida glycoprotein, ZPD, and dimeric ZP1 of chicken egg envelope are involved in sperm activation on sperm-egg interaction.
The Biochemical journal 2004;384(Pt 1):191-9.
2004: Shinji Miyata; Chihiro Sato; Shigeyuki Kitamura; Masaru Toriyama; Ken Kitajima
A major flagellum sialoglycoprotein in sea urchin sperm contains a novel polysialic acid, an alpha2,9-linked poly-N-acetylneuraminic acid chain, capped by an 8-O-sulfated sialic acid residue.
Glycobiology 2004;14(9):827-40.
2004: Shinji Asahina; Chihiro Sato; Ken Kitajima
Developmental expression of a sialyltransferase responsible for sialylation of cortical alveolus glycoprotein during oogenesis in rainbow trout (Oncorhynchus mykiss).
Journal of biochemistry 2004;136(2):189-98.
2004: Kazunori Matsuura; Ryuichi Oda; Hiromoto Kitakouji; Makoto Kiso; Ken Kitajima; Kazukiyo Kobayashi
Surface plasmon resonance study of carbohydrate-carbohydrate interaction between various gangliosides and Gg3-carrying polystyrene.
Biomacromolecules 2004;5(3):937-41.
2004: Toshio Nishikawa; Shigeo Kajii; Chihiro Sato; Zenta Yasukawa; Ken Kitajima; Minoru Isobe
Alpha-C-mannosyltryptophan is not recognized by conventional mannose-binding lectins.
Bioorganic & medicinal chemistry 2004;12(9):2343-8.
2004: Ken Kitajima
[Recent advances in studies on carbohydrate recognition processes in fertilization and development].
Seikagaku. The Journal of Japanese Biochemical Society 2004;76(3):191-200.
2003: Eri Maehashi; Chihiro Sato; Kaoru Ohta; Yoichiro Harada; Tsukasa Matsuda; Noritaka Hirohashi; William J Lennarz; Ken Kitajima
Identification of the sea urchin 350-kDa sperm-binding protein as a new sialic acid-binding lectin that belongs to the heat shock protein 110 family: implication of its binding to gangliosides in sperm lipid rafts in fertilization.
The Journal of biological chemistry 2003;278(43):42050-7.
2003: Uichiro Yabe; Chihiro Sato; Tsukasa Matsuda; Ken Kitajima
Polysialic acid in human milk. CD36 is a new member of mammalian polysialic acid-containing glycoprotein.
The Journal of biological chemistry 2003;278(16):13875-80.
2002: Chihiro Sato; Tsukasa Matsuda; Ken Kitajima
Neuronal differentiation-dependent expression of the disialic acid epitope on CD166 and its involvement in neurite formation in Neuro2A cells.
The Journal of biological chemistry 2002;277(47):45299-305.
2002: Kenji Oshima; Naohito Aoki; Takeo Kato; Ken Kitajima; Tsukasa Matsuda
Secretion of a peripheral membrane protein, MFG-E8, as a complex with membrane vesicles.
European journal of biochemistry / FEBS 2002;269(4):1209-18.
2001: Chihiro Sato; Zenta Yasukawa; N Honda; Tsukasa Matsuda; Ken Kitajima
Identification and adipocyte differentiation-dependent expression of the unique disialic acid residue in an adipose tissue-specific glycoprotein, adipo Q.
The Journal of biological chemistry 2001;276(31):28849-56.
2001: Daisuke Nakata; A K Münster; Rita Gerardy-Schahn; N Aoki; Tsukasa Matsuda; Ken Kitajima
Molecular cloning of a unique CMP-sialic acid synthetase that effectively utilizes both deaminoneuraminic acid (KDN) and N-acetylneuraminic acid (Neu5Ac) as substrates.
Glycobiology 2001;11(8):685-92.
2001: Y Usui; M Nakase; H Hotta; Atsuo Urisu; Naohito Aoki; Ken Kitajima; Tsukasa Matsuda
A 33-kDa allergen from rice (Oryza sativa L. Japonica). cDNA cloning, expression, and identification as a novel glyoxalase I.
The Journal of biological chemistry 2001;276(14):11376-81.
2001: Y Takeuchi; R Cho; Y Iwata; K Nishimura; T Kato; Naohito Aoki; Ken Kitajima; Tsukasa Matsuda
Morphological and biochemical changes of isolated chicken egg-envelope during sperm penetration: degradation of the 97-kilodalton glycoprotein is involved in sperm-driven hole formation on the egg-envelope.
Biology of reproduction 2001;64(3):822-30.
2000: Daisuke Nakata; Brett E Close; Karen J Colley; Tsukasa Matsuda; Ken Kitajima
Molecular cloning and expression of the mouse N-acetylneuraminic acid 9-phosphate synthase which does not have deaminoneuraminic acid (KDN) 9-phosphate synthase activity.
Biochemical and biophysical research communications 2000;273(2):642-8.
2000: Chihiro Sato; H Fukuoka; Kaoru Ohta; Tsukasa Matsuda; R Koshino; Kazukiyo Kobayashi; Frederic A Troy; Ken Kitajima
Frequent occurrence of pre-existing alpha 2-->8-linked disialic and oligosialic acids with chain lengths up to 7 Sia residues in mammalian brain glycoproteins. Prevalence revealed by highly sensitive chemical methods and anti-di-, oligo-, and poly-Sia antibodies specific for defined chain lengths.
The Journal of biological chemistry 2000;275(20):15422-31.
2000: M Oubihi; Ken Kitajima; N Aoki; Tsukasa Matsuda
Spontaneous galactosylation of agalactoglycoproteins in colostrum.
FEBS letters 2000;473(2):165-8.
2000: M Oubihi; K Oshima; N Aoki; Kazukiyo Kobayashi; Ken Kitajima; Tsukasa Matsuda
An ELISA-based assay for detergent-solubilized cellular beta 1,4-galactosyltransferase activity. Use of a polyacrylamide derivative with GlcNAc-beta side chains as a solid phase acceptor substrate.
Bioscience, biotechnology, and biochemistry 2000;64(4):785-92.
2000: Kaoru Ohta; Chihiro Sato; Tsukasa Matsuda; Masaru Toriyama; Victor D Vacquier; William J Lennarz; Ken Kitajima
Co-localization of receptor and transducer proteins in the glycosphingolipid-enriched, low density, detergent-insoluble membrane fraction of sea urchin sperm.
Glycoconjugate journal 2000;17(3 -4):205-14.
2000: Kaoru Ohta; Chihiro Sato; Tsukasa Matsuda; Masaru Toriyama; Victor D Vacquier; Noritaka Hirohashi; William J Lennarz; Ken Kitajima
Lipid raft on gametic cells as a functional domain for sperm-egg interaction coupled with signal transduction.
Zygote (Cambridge, England) 2000;8 Suppl 1():S63.
1999: T Angata; Daisuke Nakata; Tsukasa Matsuda; Ken Kitajima; Frederic A Troy
Biosynthesis of KDN (2-keto-3-deoxy-D-glycero-D-galacto-nononic acid). Identification and characterization of a KDN-9-phosphate synthetase activity from trout testis.
The Journal of biological chemistry 1999;274(33):22949-56.
1999: T Angata; Daisuke Nakata; Tsukasa Matsuda; Ken Kitajima
Elevated expression of free deaminoneuraminic acid in mammalian cells cultured in mannose-rich media.
Biochemical and biophysical research communications 1999;261(2):326-31.
1999: Kaoru Ohta; Chihiro Sato; Tsukasa Matsuda; Masaru Toriyama; William J Lennarz; Ken Kitajima
Isolation and characterization of low density detergent-insoluble membrane (LD-DIM) fraction from sea urchin sperm.
Biochemical and biophysical research communications 1999;258(3):616-23.
1999: Y Takeuchi; K Nishimura; Naohito Aoki; T Adachi; Chihiro Sato; Ken Kitajima; Tsukasa Matsuda
A 42-kDa glycoprotein from chicken egg-envelope, an avian homolog of the ZPC family glycoproteins in mammalian Zona pellucida. Its first identification, cDNA cloning and granulosa cell-specific expression.
European journal of biochemistry / FEBS 1999;260(3):736-42.
1999: K Oshima; N Aoki; M Negi; M Kishi; Ken Kitajima; Tsukasa Matsuda
Lactation-dependent expression of an mRNA splice variant with an exon for a multiply O-glycosylated domain of mouse milk fat globule glycoprotein MFG-E8.
Biochemical and biophysical research communications 1999;254(3):522-8.
1999: Chihiro Sato; Sadako Inoue; Tsukasa Matsuda; Ken Kitajima
Fluorescent-assisted detection of oligosialyl units in glycoconjugates.
Analytical biochemistry 1999;266(1):102-9.
1998: Chihiro Sato; Sadako Inoue; Tsukasa Matsuda; Ken Kitajima
Development of a highly sensitive chemical method for detecting alpha2-->8-linked oligo/polysialic acid residues in glycoproteins blotted on the membrane.
Analytical biochemistry 1998;261(2):191-7.
1998: S Fuchizawa; Kimio Furuhata; Tsukasa Matsuda; Ken Kitajima
Induction of KDNase Sm, a deaminoneuraminic acid (KDN) residue-specific sialidase from Sphingobacterium multivorum, using synthetic KDN-glycosides.
Biochemical and biophysical research communications 1998;248(3):505-10.
1998: M Oubihi; Ken Kitajima; Kazukiyo Kobayashi; T Adachi; N Aoki; Tsukasa Matsuda
Development of an enzyme-linked immunosorbent assay-based method for measuring galactosyltransferase activity using a synthetic glycopolymer acceptor substrate.
Analytical biochemistry 1998;257(2):169-75.
1998: M Nakase; Y Usui; A M Alvarez-Nakase; T Adachi; Atsuo Urisu; R Nakamura; Naohito Aoki; Ken Kitajima; Tsukasa Matsuda
Cereal allergens: rice-seed allergens with structural similarity to wheat and barley allergens.
Allergy 1998;53(46 Suppl):55-7.
1997: Ken Kitajima; Yorinao Inoue; Sadako Inoue
[Recent advances in glycobiology on KDN-containing glycoconjugates].
Seikagaku. The Journal of Japanese Biochemical Society 1997;69(1):44-51.