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Shigeyuki Kitamura

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Nagisa Kamikyouden; Masanori Kuroyanagi; Tsuyoshi Murahashi; Shigeru Ohta; Seigo Sanoh; Kazumi Sugihara; Naoto Uramaru; Yoko Watanabe; Shigeyuki Kitamura
2,5-Dihydroxy-4-methoxybenzophenone: a novel major in vitro metabolite of benzophenone-3 formed by rat and human liver microsomes.
Kohei Kawabata; Shigeyuki Kitamura; Seigo Sanoh; Kazumi Sugihara; Shigeru Ohta
Photodegradation of pharmaceuticals in the aquatic environment by sunlight and UV-A, -B and -C irradiation.
Seigo Sanoh; Kazumi Sugihara; Chise Tateno; Yoshitaka Tayama; Naoto Uramaru; Toru Horie; Aya Horiguchi; Shigeyuki Kitamura; Yaichiro Kotake; Hiroki Ohshita; Shigeru Ohta
Predictability of metabolism of ibuprofen and naproxen using chimeric mice with human hepatocytes.

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2013: Nagisa Kamikyouden; Masanori Kuroyanagi; Tsuyoshi Murahashi; Shigeru Ohta; Seigo Sanoh; Kazumi Sugihara; Naoto Uramaru; Yoko Watanabe; Shigeyuki Kitamura
2,5-Dihydroxy-4-methoxybenzophenone: a novel major in vitro metabolite of benzophenone-3 formed by rat and human liver microsomes.
Xenobiotica; the fate of foreign compounds in biological systems 2013;43(6):514-9.
2013: Kohei Kawabata; Shigeyuki Kitamura; Seigo Sanoh; Kazumi Sugihara; Shigeru Ohta
Photodegradation of pharmaceuticals in the aquatic environment by sunlight and UV-A, -B and -C irradiation.
The Journal of toxicological sciences 2013;38(2):215-23.
2012: Seigo Sanoh; Kazumi Sugihara; Chise Tateno; Yoshitaka Tayama; Naoto Uramaru; Toru Horie; Aya Horiguchi; Shigeyuki Kitamura; Yaichiro Kotake; Hiroki Ohshita; Shigeru Ohta
Predictability of metabolism of ibuprofen and naproxen using chimeric mice with human hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 2012;40(12):2267-72.
2012: Seigo Sanoh; Kazumi Sugihara; Chise Tateno; Yoshitaka Tayama; Toru Horie; Aya Horiguchi; Shigeyuki Kitamura; Yaichiro Kotake; Hiroki Ohshita; Shigeru Ohta
Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver.
Drug metabolism and disposition: the biological fate of chemicals 2012;40(2):322-8.
2012: Kana Matsubara; Shigeru Ohta; Seigo Sanoh; Kazumi Sugihara; Shigeyuki Kitamura; Nariaki Fujimoto
An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide.
Toxicology letters 2012;208(1):30-5.
2012: Yoshitaka Tayama; Shigeyuki Kitamura; Katsushi Miyake; Seigo Sanoh; Kazumi Sugihara; Shigeru Ohta
Developmental changes of aldehyde oxidase activity and protein expression in human liver cytosol.
Drug metabolism and pharmacokinetics 2012;27(5):543-7.
2011: Nariaki Fujimoto; Shigeyuki Kitamura; Jun Kanno
Androgen dependent transcription of a mouse prostatic protein gene, PSP94: involvement of estrogen receptors.
The Journal of steroid biochemistry and molecular biology 2011;127(3-5):301-6.
2011: Yoshitaka Tayama; Kazumi Sugihara; Seigo Sanoh; Katsushi Miyake; Shushi Morita; Shigeyuki Kitamura; Shigeru Ohta
Effect of tea beverages on aldehyde oxidase activity.
Drug metabolism and pharmacokinetics 2011;26(1):94-101.
2010: Naoto Uramaru; Hidenari Shigematsu; Akihisa Toda; Reiko Eyanagi; Shigeyuki Kitamura; Shigeru Ohta
Design, synthesis, and pharmacological activity of nonallergenic pyrazolone-type antipyretic analgesics.
Journal of medicinal chemistry 2010;53(24):8727-33.
2009: Nariaki Fujimoto; Tomoharu Suzuki; Shigeru Ohta; Shigeyuki Kitamura
Identification of rat prostatic secreted proteins using mass spectrometric analysis and androgen-dependent mRNA expression.
Journal of andrology 2009;30(6):669-78.
2009: Tae Inoue; Kazumi Sugihara; Hiroki Ohshita; Toru Horie; Shigeyuki Kitamura; Shigeru Ohta
Prediction of human disposition toward S-3H-warfarin using chimeric mice with humanized liver.
Drug metabolism and pharmacokinetics 2009;24(2):153-60.
2008: Tae Inoue; Kayoko Nitta; Kazumi Sugihara; Toru Horie; Shigeyuki Kitamura; Shigeru Ohta
CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(12):2429-33.
2008: Shigeyuki Kitamura; Kayoko Nitta; Yoshitaka Tayama; Chiaki Tanoue; Kazumi Sugihara; Tae Inoue; Toru Horie; Shigeru Ohta
Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(7):1202-5.
2008: Kazumi Sugihara; Takashige Okayama; Shigeyuki Kitamura; Keisuke Yamashita; Mineo Yasuda; Shinichi Miyairi; Yasushi Minobe; Shigeru Ohta
Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo.
Archives of toxicology 2008;82(1):5-11.
2007: Yuri Nakamura; Kazumi Sugihara; Tomomichi Sone; Masakazu Isobe; Shigeru Ohta; Shigeyuki Kitamura
The in vitro metabolism of a pyrethroid insecticide, permethrin, and its hydrolysis products in rats.
Toxicology 2007;235(3):176-84.
2007: Nariaki Fujimoto; Osamu Nakajima; Shigeyuki Kitamura; Shigeru Ohta
In vivo function of the 5' flanking region of mouse estrogen receptor beta gene.
The Journal of steroid biochemistry and molecular biology 2007;105(1-5):57-62.
2007: Yoshitaka Tayama; Aya Moriyasu; Kazumi Sugihara; Shigeru Ohta; Shigeyuki Kitamura
Developmental changes of aldehyde oxidase in postnatal rat liver.
Drug metabolism and pharmacokinetics 2007;22(2):119-24.
2007: Yoshitaka Tayama; K Miyake; Kazumi Sugihara; Shigeyuki Kitamura; Masashi Kobayashi; S Morita; Shigeru Ohta; Kenji Kihira
Developmental changes of aldehyde oxidase activity in young Japanese children.
Clinical pharmacology and therapeutics 2007;81(4):567-72.
2007: Tomoharu Suzuki; Nariaki Fujimoto; Shigeyuki Kitamura; Shigeru Ohta
Quantitative determination of lobe specificity of mRNA expression of androgen-dependent genes in the rat prostate gland.
Endocrine journal 2007;54(1):123-32.
2007: Koji Ohashi; Takeshi Yamazaki; Shigeyuki Kitamura; Shigeru Ohta; Shunsuke Izumi; Shiro Kominami
Allosteric inhibition of rat neuronal nitric-oxide synthase caused by interference with the binding of calmodulin to the enzyme.
Biochimica et biophysica acta 2007;1770(2):231-40.
2006: Aya Moriyasu; Kazumi Sugihara; Keiko Nakatani; Shigeru Ohta; Shigeyuki Kitamura
In vivo-in vitro relationship of methotrexate 7-hydroxylation by aldehyde oxidase in four different strain rats.
Drug metabolism and pharmacokinetics 2006;21(6):485-91.
2006: Nariaki Fujimoto; Yukimi Akimoto; Tomoharu Suzuki; Shigeyuki Kitamura; Shigeru Ohta
Identification of prostatic-secreted proteins in mice by mass spectrometric analysis and evaluation of lobe-specific and androgen-dependent mRNA expression.
The Journal of endocrinology 2006;190(3):793-803.
2006: Shigeyuki Kitamura; Kazumi Sugihara; Shigeru Ohta
Drug-metabolizing ability of molybdenum hydroxylases.
Drug metabolism and pharmacokinetics 2006;21(2):83-98.
2006: Kazumi Sugihara; Yoshitaka Tayama; Kazuhiro Shimomiya; Daisuke Yoshimoto; Shigeru Ohta; Shigeyuki Kitamura
Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(2):208-12.
2005: Osamu Ueda; Kazumi Sugihara; Shigeru Ohta; Shigeyuki Kitamura
Involvement of molybdenum hydroxylases in reductive metabolism of nitro polycyclic aromatic hydrocarbons in mammalian skin.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(9):1312-8.
2005: Yoichi Kohno; Shigeyuki Kitamura; Seigo Sanoh; Kazumi Sugihara; Nariaki Fujimoto; Shigeru Ohta
Metabolism of the alpha,beta-unsaturated ketones, chalcone and trans-4-phenyl-3-buten-2-one, by rat liver microsomes and estrogenic activity of the metabolites.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(8):1115-23.
2005: Yoichi Kohno; Shigeyuki Kitamura; Tsuyoshi Yamada; Kazumi Sugihara; Shigeru Ohta
Production of superoxide radical in reductive metabolism of a synthetic food-coloring agent, indigocarmine, and related compounds.
Life sciences 2005;77(6):601-14.
2005: Shigeyuki Kitamura; Tomoharu Suzuki; Seigo Sanoh; Ryuki Kohta; Norimasa Jinno; Kazumi Sugihara; Shin'ichi Yoshihara; Nariaki Fujimoto; Hiromitsu Watanabe; Shigeru Ohta
Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds.
Toxicological sciences : an official journal of the Society of Toxicology 2005;84(2):249-59.
2005: Shigeyuki Kitamura; Norimasa Jinno; Tomoharu Suzuki; Kazumi Sugihara; Shigeru Ohta; Hiroaki Kuroki; Nariaki Fujimoto
Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture.
Toxicology 2005;208(3):377-87.
2005: Shigeyuki Kitamura; Teruhisa Kato; Mitsuru Iida; Norimasa Jinno; Tomoharu Suzuki; Shigeru Ohta; Nariaki Fujimoto; Hideki Hanada; Keiko Kashiwagi; Akihiko Kashiwagi
Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis.
Life sciences 2005;76(14):1589-601.
2005: Tomoharu Suzuki; Shigeyuki Kitamura; Ryuki Khota; Kazumi Sugihara; Nariaki Fujimoto; Shigeru Ohta
Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreens.
Toxicology and applied pharmacology 2005;203(1):9-17.
2005: Nariaki Fujimoto; Kosuke Asano; Tsuguru Usui; Hiroaki Honda; Shigeyuki Kitamura
Cloning and characterization of the 5'-flanking region of the rat estrogen receptor beta gene.
The Journal of steroid biochemistry and molecular biology 2005;94(1-3):15-21.
2004: Koji Ohashi; Shiro Kominami; Takeshi Yamazaki; Shigeru Ohta; Shigeyuki Kitamura
Inhibitory effect of organotin compounds on rat neuronal nitric oxide synthase through interaction with calmodulin.
Biochemical and biophysical research communications 2004;324(1):178-85.
2004: Nariaki Fujimoto; Tomoharu Suzuki; Hiroaki Honda; Shigeyuki Kitamura
Estrogen enhancement of androgen-responsive gene expression in hormone-induced hyperplasia in the ventral prostate of F344 rats.
Cancer science 2004;95(9):711-5.
2004: Kazumi Sugihara; Shigeyuki Kitamura; Tsuyoshi Yamada; Takashige Okayama; Shigeru Ohta; Keisuke Yamashita; Mineo Yasuda; Yoshiaki Fujii-Kuriyama; Ken'ich Saeki; Saburo Matsui; Tomonari Matsuda
Aryl hydrocarbon receptor-mediated induction of microsomal drug-metabolizing enzyme activity by indirubin and indigo.
Biochemical and biophysical research communications 2004;318(2):571-8.
2004: Nariaki Fujimoto; Norimasa Jinno; Shigeyuki Kitamura
Activation of estrogen response element dependent transcription by thyroid hormone with increase in estrogen receptor levels in a rat pituitary cell line, GH3.
The Journal of endocrinology 2004;181(1):77-83.
2004: Nariaki Fujimoto; Hiroaki Honda; Shigeyuki Kitamura
Effects of environmental estrogenic chemicals on AP1 mediated transcription with estrogen receptors alpha and beta.
The Journal of steroid biochemistry and molecular biology 2004;88(1):53-9.
2003: Takashi Fujimoto; Shigeyuki Kitamura; Seigo Sanoh; Kazumi Sugihara; Shin'ichi Yoshihara; Nariaki Fujimoto; Shigeru Ohta
Estrogenic activity of an environmental pollutant, 2-nitrofluorene, after metabolic activation by rat liver microsomes.
Biochemical and biophysical research communications 2003;303(2):419-26.
2003: Shigeyuki Kitamura; Tomoharu Suzuki; Shigeru Ohta; Nariaki Fujimoto
Antiandrogenic activity and metabolism of the organophosphorus pesticide fenthion and related compounds.
Environmental health perspectives 2003;111(4):503-8.
2003: Osamu Ueda; Shigeyuki Kitamura; Koji Ohashi; Kazumi Sugihara; Shigeru Ohta
Xanthine oxidase-catalyzed metabolism of 2-nitrofluorene, a carcinogenic air pollutant, in rat skin.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(4):367-72.
2003: Shigeyuki Kitamura; Motoko Ohmegi; Seigo Sanoh; Kazumi Sugihara; Shin'ichi Yoshihara; Nariaki Fujimoto; Shigeru Ohta
Estrogenic activity of styrene oligomers after metabolic activation by rat liver microsomes.
Environmental health perspectives 2003;111(3):329-34.
2003: Shigeyuki Kitamura; Tomoharu Suzuki; Tomoko Kadota; Mayumi Yoshida; Koji Ohashi; Shigeru Ohta
In vitro metabolism of fenthion and fenthion sulfoxide by liver preparations of sea bream, goldfish, and rats.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(2):179-86.
2002: Osamu Ueda; Shigeyuki Kitamura; Shigeru Ohta
Deacylation of N-arylformamides and N-arylacetamides by formamidase in rat liver.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(12):1297-9.
2002: Osamu Ueda; Shigeyuki Kitamura; Shigeru Ohta
Metabolism of 2-nitrofluorene, an environmental pollutant, by liver preparations of sea bream, Pagrus major.
Xenobiotica; the fate of foreign compounds in biological systems 2002;32(8):667-82.
2002: Shigeyuki Kitamura; Norimasa Jinno; Shigeru Ohta; Hiroaki Kuroki; Nariaki Fujimoto
Thyroid hormonal activity of the flame retardants tetrabromobisphenol A and tetrachlorobisphenol A.
Biochemical and biophysical research communications 2002;293(1):554-9.
2002: Shigeyuki Kitamura; Yoichi Kohno; Yuji Okamoto; Mitsuhiro Takeshita; Shigeru Ohta
Reductive metabolism of an alpha,beta-ketoalkyne, 4-phenyl-3-butyn-2-one, by rat liver preparations.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(4):414-20.
2002: Seigo Sanoh; Shigeyuki Kitamura; Kazumi Sugihara; Shigeru Ohta
Cytochrome P450 1A1/2 mediated metabolism of trans-stilbene in rats and humans.
Biological & pharmaceutical bulletin 2002;25(3):397-400.
2002: Shigeyuki Kitamura; Yuri Shimizu; Yuko Shiraga; Mayumi Yoshida; Kazumi Sugihara; Shigeru Ohta
Reductive metabolism of p,p'-DDT and o,p'-DDT by rat liver cytochrome P450.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(2):113-8.
2001: K Takekawa; Kazumi Sugihara; Shigeyuki Kitamura; Shigeru Ohta
Enzymatic and non-enzymatic reduction of brucine N-oxide by aldehyde oxidase and catalase.
Xenobiotica; the fate of foreign compounds in biological systems 2001;31(11):769-82.
2001: Shigeyuki Kitamura; Kazumi Sugihara; R Hosokawa; Y Akagawa; Shigeru Ohta
Extremely high drug-reductase activity based on aldehyde oxidase in monkey liver.
Biological & pharmaceutical bulletin 2001;24(7):856-9.
2001: Kazumi Sugihara; Shigeyuki Kitamura; Tsuyoshi Yamada; Shigeru Ohta; Keisuke Yamashita; Mineo Yasuda; Yoshiaki Fujii-Kuriyama
Aryl hydrocarbon receptor (AhR)-mediated induction of xanthine oxidase/xanthine dehydrogenase activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Biochemical and biophysical research communications 2001;281(5):1093-9.
2001: Osamu Ueda; Shigeyuki Kitamura; Y Huruse; T Saito; Yukari Kanzaki; Y Yano; K Tatsumi; Shigeru Ohta
Metabolism of 2-nitrofluorene, an environmental pollutant, and 2-acetylaminofluorene in fish.
Bulletin of environmental contamination and toxicology 2001;66(3):371-8.
2001: Osamu Ueda; Shigeyuki Kitamura; R Kubo; Y Yano; Yukari Kanzaki; T Fujimoto; K Tatsumi; Shigeru Ohta
Metabolism of 2-nitrofluorene, 2-aminofluorene and 2-acylaminofluorenes in rat and dog and the role of intestinal bacteria.
Xenobiotica; the fate of foreign compounds in biological systems 2001;31(1):33-49.
2000: Kazumi Sugihara; Shigeyuki Kitamura; Seigo Sanoh; Shigeru Ohta; Nariaki Fujimoto; S Maruyama; A Ito
Metabolic activation of the proestrogens trans-stilbene and trans-stilbene oxide by rat liver microsomes.
Toxicology and applied pharmacology 2000;167(1):46-54.
2000: Shigeyuki Kitamura; T Kadota; Mayumi Yoshida; Norimasa Jinno; Shigeru Ohta
Whole-body metabolism of the organophosphorus pesticide, fenthion, in goldfish, Carassius auratus.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2000;126(3):259-66.
2000: Kazumi Sugihara; Y Katsuma; Shigeyuki Kitamura; Shigeru Ohta; Morioki Fujitani; Hideaki Shintani
Cynomolgus monkey liver aldehyde oxidase: extremely high oxidase activity and an attempt at purification.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2000;126(1):53-60.
2000: Kazumi Sugihara; Shigeyuki Kitamura; Shigeru Ohta; K Tatsumi
Reduction of hydroxamic acids to the corresponding amides catalyzed by rabbit blood.
Xenobiotica; the fate of foreign compounds in biological systems 2000;30(5):457-67.
2000: Shigeyuki Kitamura; M Mita; K Matsuda; Shigeru Ohta; K Tatsumi
Reduction of stilbene oxide and styrene oxide to the corresponding alkenes by intestinal bacteria.
Xenobiotica; the fate of foreign compounds in biological systems 2000;30(4):359-69.
2000: Shigeyuki Kitamura; Y Shiraishi; M Mita; H Sueki; C Maeda; K Tatsumi
Reductive metabolism of stilbene oxide and styrene oxide to the olefins in rats.
Biological & pharmaceutical bulletin 2000;23(2):265-8.
1999: Shigeyuki Kitamura; K Sugihara; K Nakatani; Shigeru Ohta; T Ohhara; S Ninomiya; C E Green; Charles A Tyson
Variation of hepatic methotrexate 7-hydroxylase activity in animals and humans.
IUBMB life 1999;48(6):607-11.
1999: Yuji Okamoto; Shigeyuki Kitamura; Mitsuhiro Takeshita; Shigeru Ohta
Microsomal carbonyl reductase responsible for reduction of 4-phenyl-3-buten-2-one in rats.
IUBMB life 1999;48(5):543-7.
1999: Kazumi Sugihara; Y Katsuma; C Tanaka; Shigeyuki Kitamura
Purification and some properties of hamster liver aldehyde oxidase.
Biological & pharmaceutical bulletin 1999;22(11):1246-8.
1999: Shigeyuki Kitamura; A Terada; H Kamio; Kazumi Sugihara; N Koga; Shigeru Ohta
DT-diaphorase-like quinone reductase in rat plasma.
Biological & pharmaceutical bulletin 1999;22(8):883-5.
1999: Shigeyuki Kitamura; M Mita; Y Shimizu; Kazumi Sugihara; Shigeru Ohta
Conversion of dieldrin to aldrin by intestinal bacteria in rats.
Biological & pharmaceutical bulletin 1999;22(8):880-2.
1999: Shigeyuki Kitamura; Yuji Okamoto; Mitsuhiro Takeshita; Shigeru Ohta
Reductive metabolism In vivo of trans-4-phenyl-3-buten-2-one in rats and dogs.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(7):767-9.
1999: Shigeyuki Kitamura; K Nakatani; Kazumi Sugihara; Shigeru Ohta
Strain differences of the ability to hydroxylate methotrexate in rats.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1999;122(3):331-6.
1999: Shigeyuki Kitamura; K Takekawa; Kazumi Sugihara; K Tatsumi; Shigeru Ohta
Pseudoenzymatic reduction of N-hydroxy-2-acetylaminofluorene to 2-acetylaminofluorene mediated by cytochrome P450.
Carcinogenesis 1999;20(2):347-50.
1999: Shigeyuki Kitamura; M Kuwasako; Shigeru Ohta; K Tatsumi
Reductive debromination of (alpha-bromoiso-valeryl)urea by intestinal bacteria.
The Journal of pharmacy and pharmacology 1999;51(1):79-84.
1999: Shigeyuki Kitamura; M Kuwasako; Kazumi Sugihara; K Tatsumi; Shigeru Ohta
Debromination of (alpha-bromoiso-valeryl)urea catalysed by rat blood.
The Journal of pharmacy and pharmacology 1999;51(1):73-8.
1999: Shigeyuki Kitamura; Kazumi Sugihara; K Tatsumi
A unique tertiary amine N-oxide reduction system composed of quinone reductase and heme in rat liver preparations.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(1):92-7.
1998: Shigeyuki Kitamura; A Terada; N Inoue; H Kamio; Shigeru Ohta; K Tatsumi
Quinone-dependent tertiary amine N-oxide reduction in rat blood.
Biological & pharmaceutical bulletin 1998;21(12):1344-7.
1998: Kazumi Sugihara; Shigeyuki Kitamura; Shigeru Ohta
Reductive dechlorination of DDT to DDD by rat blood.
Biochemistry and molecular biology international 1998;45(1):85-91.
1997: Shigeyuki Kitamura; K Tatsumi
Purification of NADPH-linked and NADH-linked quinone reductases from liver cytosol of sea bream, Pagrus major.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1997;118(3):675-80.
1997: K Takekawa; Kazumi Sugihara; Shigeyuki Kitamura; K Tatsumi
Nonenzymatic reduction of brucine N-oxide by the heme group of cytochrome P450.
Biochemistry and molecular biology international 1997;42(5):977-81.
1997: Shigeyuki Kitamura; K Tatsumi
Menadione-dependent reduction of tertiary amine N-oxide by rat liver cytosol.
Biochemistry and molecular biology international 1997;42(2):271-6.
1997: Kazumi Sugihara; Shigeyuki Kitamura; K Tatsumi; Toshimasa Asahara; K Dohi
Differences in aldehyde oxidase activity in cytosolic preparations of human and monkey liver.
Biochemistry and molecular biology international 1997;41(6):1153-60.
1997: Yoshio Takeda; Hiromu K Mishima; Shigeyuki Kitamura; K Tatsumi
Purification and characterization of alpha,beta-ketoalkene double bond reductases from bovine eyes.
Current eye research 1997;16(4):327-32.
1997: Shigeyuki Kitamura; Kazumi Sugihara; M Kuwasako; K Tatsumi
The role of mammalian intestinal bacteria in the reductive metabolism of zonisamide.
The Journal of pharmacy and pharmacology 1997;49(3):253-6.
1997: Shigeyuki Kitamura; K Tatsumi
1-Nitropyrene-metabolizing activities of fish liver preparations.
Bulletin of environmental contamination and toxicology 1997;58(3):448-55.
1996: Shigeyuki Kitamura; K Tatsumi
Metabolism in vivo of 1-nitropyrene, an environmental pollutant, in fish.
Biological & pharmaceutical bulletin 1996;19(11):1524-6.
1996: Kazumi Sugihara; Shigeyuki Kitamura; K Tatsumi
S-(-)-nicotine-1'-N-oxide reductase activity of rat liver aldehyde oxidase.
Biochemistry and molecular biology international 1996;40(3):535-41.
1996: K Oka; Shigeyuki Kitamura; K Tatsumi
Involvement of a cytochrome P450 system in microsomal debromination of alpha-(bromisovaleryl)urea.
The Journal of pharmacy and pharmacology 1996;48(9):930-2.
1996: M Ishida; Shigeyuki Kitamura; K Tatsumi
Purification of an alpha,beta-ketoalkene double bond reductase from Salmonella typhimurium.
Biochemistry and molecular biology international 1996;39(6):1157-65.
1996: Shigeyuki Kitamura; H Katsura; K Tatsumi
Multiplicity of rat liver 15-ketoprostaglandin delta 13-reductases.
Prostaglandins 1996;52(1):35-49.
1996: O Ueda; Shigeyuki Kitamura; K Tatsumi
Further metabolism of 2-formylaminofluorene, a metabolite of 2-aminofluorene, in rats.
Biological & pharmaceutical bulletin 1996;19(2):330-3.
1996: Kazumi Sugihara; Shigeyuki Kitamura; K Tatsumi
Involvement of mammalian liver cytosols and aldehyde oxidase in reductive metabolism of zonisamide.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(2):199-202.
1995: Kazumi Sugihara; Shigeyuki Kitamura; K Tatsumi
Strain differences of liver aldehyde oxidase activity in rats.
Biochemistry and molecular biology international 1995;37(5):861-9.
1995: F Okumura; O Ueda; Shigeyuki Kitamura; K Tatsumi
N-acetylation and N-formylation of carcinogenic arylamines and related compounds in dogs.
Carcinogenesis 1995;16(1):71-6.
1994: Shigeyuki Kitamura; Kazumi Sugihara; K Tatsumi
Reductase activity of aldehyde oxidase toward the carcinogen N-hydroxy-2-acetylaminofluorene and the related hydroxamic acids.
Biochemistry and molecular biology international 1994;34(6):1197-203.
1994: Y Hirao; Shigeyuki Kitamura; K Tatsumi
Epoxide reductase activity of mammalian liver cytosols and aldehyde oxidase.
Carcinogenesis 1994;15(4):739-43.
1993: Shigeyuki Kitamura; H Katsura; K Tatsumi
Purification of a 15-ketoprostaglandin delta 13-reductase from rat liver and its ability to reduce the double bond of xenobiotics.
Biochemistry and molecular biology international 1993;30(5):839-47.
1993: H Nikaido; Misaki Moriishi; Hiromu K Mishima; Shigeyuki Kitamura; K Tatsumi
15-Ketoprostaglandin delta 13-reductase activity in bovine ocular tissues.
Current eye research 1993;12(1):17-22.
1992: K Tatsumi; Shigeyuki Kitamura; M Kato; K Hiraoka
Metabolism of sodium nifurstyrenate, a veterinary antimicrobial nitrofuran, in animals and fish.
Drug metabolism and disposition: the biological fate of chemicals 1992;20(2):226-33.
1992: H Nikaido; Hiromu K Mishima; Misaki Moriishi; Shigeyuki Kitamura; K Tatsumi
Oxidation of 1,1-diphenylhydrazine to N-nitrosodiphenylamine by superoxide radical in the eye.
Japanese journal of ophthalmology 1992;36(1):103-7.
1989: S Shimada; Hiromu K Mishima; H Nikaido; Shigeyuki Kitamura; K Tatsumi
Metabolism of drugs in the eye. Menadione-dependent reduction of tertiary amine N-oxide by preparations from bovine ocular tissues.
Current eye research 1989;8(12):1309-13.
1989: S Shimada; Hiromu K Mishima; H Nikaido; Shigeyuki Kitamura; K Tatsumi
Purification of aldehyde oxidase from bovine ciliary body.
Current eye research 1989;8(7):721-6.
1989: K Tatsumi; Shigeyuki Kitamura; H Amano; K Ueda
Comparative study on metabolic formation of N-arylformamides and N-arylacetamides from carcinogenic arylamines in mammalian species.
Cancer research 1989;49(8):2059-64.
1988: S Shimada; Hiromu K Mishima; Shigeyuki Kitamura; K Tatsumi
Metabolism of drugs in the eye. Drug-reducing activity of preparations from bovine ciliary body.
Current eye research 1988;7(11):1069-75.