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Kazuyuki Kitatani

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David M Perry; Patrick Roddy; Mohamad El-Osta; Kazuyuki Kitatani; Yusuf A Hannun
Identification and characterization of protein phosphatase 2C activation by ceramide.
Hesham M El-Shewy; Ayad A Jaffa; Kazuyuki Kitatani; Mi-Hye Lee; Souzan A Abdel-Samie; Abdelmohsen M Al Qalam; Viviana Anelli; Lina M Obeid; Louis M Luttrell
Phospholipase C and protein kinase C-β 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation.
Russell W Jenkins; Christopher J Clarke; Daniel Canals; Ashley J Snider; Christopher R Gault; Linda Heffernan-Stroud; Bill X Wu; Fabio Simbari; Patrick Roddy; Kazuyuki Kitatani; Lina M Obeid; Yusuf A Hannun
Regulation of CC ligand 5/RANTES by acid sphingomyelinase and acid ceramidase.

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All Publications

2012: David M Perry; Patrick Roddy; Mohamad El-Osta; Kazuyuki Kitatani; Yusuf A Hannun
Identification and characterization of protein phosphatase 2C activation by ceramide.
Journal of lipid research 2012;53(8):1513-21.
2011: Hesham M El-Shewy; Ayad A Jaffa; Kazuyuki Kitatani; Mi-Hye Lee; Souzan A Abdel-Samie; Abdelmohsen M Al Qalam; Viviana Anelli; Lina M Obeid; Louis M Luttrell
Phospholipase C and protein kinase C-β 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation.
Molecular endocrinology (Baltimore, Md.) 2011;25(12):2144-56.
2011: Russell W Jenkins; Christopher J Clarke; Daniel Canals; Ashley J Snider; Christopher R Gault; Linda Heffernan-Stroud; Bill X Wu; Fabio Simbari; Patrick Roddy; Kazuyuki Kitatani; Lina M Obeid; Yusuf A Hannun
Regulation of CC ligand 5/RANTES by acid sphingomyelinase and acid ceramidase.
The Journal of biological chemistry 2011;286(15):13292-303.
2011: Thomas D Mullen; Stefka Spassieva; Russell W Jenkins; Kazuyuki Kitatani; Jacek Bielawski; Yusuf A Hannun; Lina M Obeid
Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism.
Journal of lipid research 2011;52(1):68-77.
2010: Russell W Jenkins; Daniel Canals; Jolanta Idkowiak-Baldys; Fabio Simbari; Patrick Roddy; David M Perry; Kazuyuki Kitatani; Chiara Luberto; Yusuf A Hannun
Regulated secretion of acid sphingomyelinase: implications for selectivity of ceramide formation.
The Journal of biological chemistry 2010;285(46):35706-18.
2009: Kazuyuki Kitatani; Kely Sheldon; Vinodh Rajagopalan; Viviana Anelli; Russell W Jenkins; Ying Sun; Gregory A Grabowski; Lina M Obeid; Yusuf A Hannun
Involvement of acid beta-glucosidase 1 in the salvage pathway of ceramide formation.
The Journal of biological chemistry 2009;284(19):12972-8.
2009: Kazuyuki Kitatani; Kely Sheldon; Viviana Anelli; Russell W Jenkins; Ying Sun; Gregory A Grabowski; Lina M Obeid; Yusuf A Hannun
Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid.
The Journal of biological chemistry 2009;284(19):12979-88.
2008: Kazuyuki Kitatani; Jolanta Idkowiak-Baldys; Yusuf A Hannun
The sphingolipid salvage pathway in ceramide metabolism and signaling.
Cellular signalling 2008;20(6):1010-8.
2008: Kumaran Sundaram; Santhosh K Mani; Kazuyuki Kitatani; Kongming Wu; Richard G Pestell; Sakamuri V Reddy
DACH1 negatively regulates the human RANK ligand gene expression in stromal/preosteoblast cells.
Journal of cellular biochemistry 2008;103(6):1747-59.
2007: Kazuyuki Kitatani; Jolanta Idkowiak-Baldys; Yusuf A Hannun
Mechanism of inhibition of sequestration of protein kinase C alpha/betaII by ceramide. Roles of ceramide-activated protein phosphatases and phosphorylation/dephosphorylation of protein kinase C alpha/betaII on threonine 638/641.
The Journal of biological chemistry 2007;282(28):20647-56.
2006: Kazuyuki Kitatani; Jolanta Idkowiak-Baldys; Jacek Bielawski; Tarek A Taha; Russell W Jenkins; Can E Senkal; Besim Ogretmen; Lina M Obeid; Yusuf A Hannun
Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK.
The Journal of biological chemistry 2006;281(48):36793-802.
2006: Jolanta Idkowiak-Baldys; Kevin P Becker; Kazuyuki Kitatani; Yusuf A Hannun
Dynamic sequestration of the recycling compartment by classical protein kinase C.
The Journal of biological chemistry 2006;281(31):22321-31.
2006: Tarek A Taha; Kazuyuki Kitatani; Mazen El Alwani; Jacek Bielawski; Yusuf A Hannun; Lina M Obeid
Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(3):482-4.
2005: Benjamin J Pettus; Kazuyuki Kitatani; Charles E Chalfant; Tarek A Taha; Toshihiko Kawamori; Jacek Bielawski; Lina M Obeid; Yusuf A Hannun
The coordination of prostaglandin E2 production by sphingosine-1-phosphate and ceramide-1-phosphate.
Molecular pharmacology 2005;68(2):330-5.
2005: Tarek A Taha; Kazuyuki Kitatani; Jacek Bielawski; Wonhwa Cho; Yusuf A Hannun; Lina M Obeid
Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism.
The Journal of biological chemistry 2005;280(17):17196-202.
2005: Kevin P Becker; Kazuyuki Kitatani; Jolanta Idkowiak-Baldys; Jacek Bielawski; Yusuf A Hannun
Selective inhibition of juxtanuclear translocation of protein kinase C betaII by a negative feedback mechanism involving ceramide formed from the salvage pathway.
The Journal of biological chemistry 2005;280(4):2606-12.
2004: Kazuyuki Kitatani; Satoshi Akiba; Takashi Sato
Ceramide-induced enhancement of secretory phospholipase A2 expression via generation of reactive oxygen species in tumor necrosis factor-alpha-stimulated mesangial cells.
Cellular signalling 2004;16(8):967-74.
2002: Kazuyuki Kitatani; Megumi Nemoto; Satoshi Akiba; Takashi Sato
Stimulation by de novo-synthesized ceramide of phospholipase A(2)-dependent cholesterol esterification promoted by the uptake of oxidized low-density lipoprotein in macrophages.
Cellular signalling 2002;14(8):695-701.
2001: Kazuyuki Kitatani; Satoshi Akiba; Misako Hayama; Takashi Sato
Ceramide accelerates dephosphorylation of extracellular signal-regulated kinase 1/2 to decrease prostaglandin D(2) production in RBL-2H3 cells.
Archives of biochemistry and biophysics 2001;395(2):208-14.
2001: Satoshi Akiba; R Hatazawa; K Ono; Kazuyuki Kitatani; Misako Hayama; Takashi Sato
Secretory phospholipase A2 mediates cooperative prostaglandin generation by growth factor and cytokine independently of preceding cytosolic phospholipase A2 expression in rat gastric epithelial cells.
The Journal of biological chemistry 2001;276(24):21854-62.
2000: Kazuyuki Kitatani; Satoshi Akiba; Takashi Sato
Role of phospholipase D-derived phosphatidic acid as a substrate for phospholipase A2 in RBL-2H3 cells.
Biological & pharmaceutical bulletin 2000;23(12):1430-3.
2000: Satoshi Akiba; T Murata; Kazuyuki Kitatani; Takashi Sato
Involvement of lipoxygenase pathway in docosapentaenoic acid-induced inhibition of platelet aggregation.
Biological & pharmaceutical bulletin 2000;23(11):1293-7.
2000: Kazuyuki Kitatani; T Oka; T Murata; Misako Hayama; Satoshi Akiba; Takashi Sato
Acceleration by ceramide of calcium-dependent translocation of phospholipase A2 from cytosol to membranes in platelets.
Archives of biochemistry and biophysics 2000;382(2):296-302.
1999: T Hashizume; Kazuyuki Kitatani; T Kageura; Misako Hayama; Satoshi Akiba; Takashi Sato
Ceramide enhances susceptibility of membrane phospholipids to phospholipase A2 through modification of lipid organization in platelet membranes.
Biological & pharmaceutical bulletin 1999;22(12):1275-8.
1999: Takashi Sato; T Kageura; T Hashizume; Misako Hayama; Kazuyuki Kitatani; Satoshi Akiba
Stimulation by ceramide of phospholipase A2 activation through a mechanism related to the phospholipase C-initiated signaling pathway in rabbit platelets.
Journal of biochemistry 1999;125(1):96-102.