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Jayachandran Kizhakkedathu

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Stefan Tholen; Fee Bengsch; Martin L Biniossek; Melanie Boerries; Hauke Busch; Martina Gansz; Alejandro Gomez-Auli; Jayachandran N Kizhakkedathu; Agnes Noel; Thomas Reinheckel; Oliver Schilling
Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.
Asher A Mendelson; Irina Chafeeva; Gerald A da Roza; Qiunong Guan; Jayachandran N Kizhakkedathu; Caigan Du
Hyperbranched polyglycerol is an efficacious and biocompatible novel osmotic agent in a rodent model of peritoneal dialysis.
Muhammad Imran ul-haq; Rafi Chapanian; Benjamin F L Lai; Jayachandran N Kizhakkedathu
Influence of architecture of high molecular weight linear and branched polyglycerols on their biocompatibility and biodistribution.

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2013: Stefan Tholen; Fee Bengsch; Martin L Biniossek; Melanie Boerries; Hauke Busch; Martina Gansz; Alejandro Gomez-Auli; Jayachandran N Kizhakkedathu; Agnes Noel; Thomas Reinheckel; Oliver Schilling
Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.
Molecular & cellular proteomics : MCP 2013;12(3):611-25.
2013: Asher A Mendelson; Irina Chafeeva; Gerald A da Roza; Qiunong Guan; Jayachandran N Kizhakkedathu; Caigan Du
Hyperbranched polyglycerol is an efficacious and biocompatible novel osmotic agent in a rodent model of peritoneal dialysis.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2013;33(1):15-27.
2012: Muhammad Imran ul-haq; Rafi Chapanian; Benjamin F L Lai; Jayachandran N Kizhakkedathu
Influence of architecture of high molecular weight linear and branched polyglycerols on their biocompatibility and biodistribution.
Biomaterials 2012;33(35):9135-47.
2012: Rafi Chapanian; Iren Constantinescu; Nadia Medvedev; Nicholas A A Rossi; Mark D Scott; Donald E Brooks; Jayachandran N Kizhakkedathu
Influence of polymer architecture on antigens camouflage, CD47 protection and complement mediated lysis of surface grafted red blood cells.
Biomaterials 2012;33(31):7871-83.
2012: Rajesh A Shenoi; Benjamin F L Lai; Jayachandran N Kizhakkedathu
Synthesis, characterization, and biocompatibility of biodegradable hyperbranched polyglycerols from acid-cleavable ketal group functionalized initiators.
Biomacromolecules 2012;13(10):3018-30.
2012: Rajesh A Shenoi; Jos P Varghese; Jasmine L Hamilton; Sonja Horte; Rajesh Kumar Kainthan; Benjamin F L Lai; Muthiah Manoharan; Jayaprakash K Narayanannair; Kallanthottathil G Rajeev; Jayachandran N Kizhakkedathu
Branched multifunctional polyether polyketals: variation of ketal group structure enables unprecedented control over polymer degradation in solution and within cells.
Journal of the American Chemical Society 2012;134(36):14945-57.
2012: Xifei Yu; Irina Chafeeva; Wei Chen; Sonja Horte; Johan Janzen; Rajesh Kumar Kainthan; Jayachandran N Kizhakkedathu; Zonghua Liu; Donald E Brooks
Polyvalent choline phosphate as a universal biomembrane adhesive.
Nature materials 2012;11(5):468-76.
2012: Rafi Chapanian; Iren Constantinescu; Donald E Brooks; Mark D Scott; Jayachandran N Kizhakkedathu
In vivo circulation, clearance, and biodistribution of polyglycerol grafted functional red blood cells.
Biomaterials 2012;33(10):3047-57.
2012: Kai Yu; Benjamin F L Lai; Jayachandran N Kizhakkedathu
Carbohydrate structure dependent hemocompatibility of biomimetic functional polymer brushes on surfaces.
Advanced healthcare materials 2012;1(2):199-213.
2012: Guangzheng Gao; Robert E W Hancock; Jason Kindrachuk; John T J Cheng; Suzana K Straus; Jayachandran N Kizhakkedathu
Biomembrane interactions reveal the mechanism of action of surface-immobilized host defense IDR-1010 peptide.
Chemistry & biology 2012;19(2):199-209.
2011: Stefan Tholen; Juliane Weisser; Martin L Biniossek; Anna-Lena Gessler; Jayachandran N Kizhakkedathu; Sebastian Müller; Thomas Reinheckel; Oliver Schilling
Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts.
Biological chemistry 2011;392(11):961-71.
2011: Guangzheng Gao; Robert E W Hancock; Jason Kindrachuk; Donald E Brooks; Kai Yu; Jayachandran N Kizhakkedathu
Antibacterial surfaces based on polymer brushes: investigation on the influence of brush properties on antimicrobial peptide immobilization and antimicrobial activity.
Biomacromolecules 2011;12(10):3715-27.
2011: Oded Kleifeld; Anna Prudova; Ulrich auf dem Keller; Alain Doucet; Magda Gioia; Jayachandran N Kizhakkedathu; Christopher M Overall
Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates.
Nature protocols 2011;6(10):1578-611.
2011: Patrick Beaudette; Alain Doucet; Pitter F Huesgen; Christopher M Overall; Nicholas A A Rossi; Rajesh A Shenoi; Xifei Yu; Jayachandran N Kizhakkedathu
Development of soluble ester-linked aldehyde polymers for proteomics.
Analytical chemistry 2011;83(17):6500-10.
2011: Guangzheng Gao; Dirk Lange; Kai Hilpert; Jason Kindrachuk; Yuquan Zou; John T J Cheng; Kazemzadeh-Narbat Mehdi; Kai Yu; Rizhi Wang; Suzana K Straus; Donald E Brooks; Ben H Chew; Robert E W Hancock; Jayachandran N Kizhakkedathu
The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides.
Biomaterials 2011;32(16):3899-909.
2011: Yuquan Zou; Adriel Lam; Donald E Brooks; A Srikantha Phani; Jayachandran N Kizhakkedathu
Bending and stretching actuation of soft materials through surface-initiated polymerization.
Angewandte Chemie (International ed. in English) 2011;50(22):5116-9.
2011: Lucy Ye; Kevin Letchford; Markus Heller; Richard T Liggins; Dechi Guan; Jayachandran N Kizhakkedathu; Donald E Brooks; John K Jackson; Helen M Burt
Synthesis and characterization of carboxylic acid conjugated, hydrophobically derivatized, hyperbranched polyglycerols as nanoparticulate drug carriers for cisplatin.
Biomacromolecules 2011;12(1):145-55.
2011: Alain Doucet; Oded Kleifeld; Jayachandran N Kizhakkedathu; Christopher M Overall
Identification of proteolytic products and natural protein N-termini by Terminal Amine Isotopic Labeling of Substrates (TAILS).
Methods in molecular biology (Clifton, N.J.) 2011;753():273-87.
2010: Yuquan Zou; Benjamin F L Lai; Jayachandran N Kizhakkedathu; Donald E Brooks
Inhibitory effect of hydrophilic polymer brushes on surface-induced platelet activation and adhesion.
Macromolecular bioscience 2010;10(12):1432-43.
2010: Jayachandran N Kizhakkedathu; A Louise Creagh; Rajesh A Shenoi; Nicholas A A Rossi; Donald E Brooks; Timmy Chan; Jonathan Lam; Srinivasa R Dandepally; Charles A Haynes
High molecular weight polyglycerol-based multivalent mannose conjugates.
Biomacromolecules 2010;11(10):2567-75.
2010: Benjamin F L Lai; A Louise Creagh; Johan Janzen; Charles A Haynes; Donald E Brooks; Jayachandran N Kizhakkedathu
The induction of thrombus generation on nanostructured neutral polymer brush surfaces.
Biomaterials 2010;31(26):6710-8.
2010: Benjamin F L Lai; Yuquan Zou; Donald E Brooks; Jayachandran N Kizhakkedathu
The influence of poly-N-[(2,2-dimethyl-1,3-dioxolane)methyl]acrylamide on fibrin polymerization, cross-linking and clot structure.
Biomaterials 2010;31(22):5749-58.
2010: Nicholas A A Rossi; Iren Constantinescu; Rajesh Kumar Kainthan; Donald E Brooks; Mark D Scott; Jayachandran N Kizhakkedathu
Red blood cell membrane grafting of multi-functional hyperbranched polyglycerols.
Biomaterials 2010;31(14):4167-78.
2010: Nicholas A A Rossi; Iren Constantinescu; Donald E Brooks; Mark D Scott; Jayachandran N Kizhakkedathu
Enhanced cell surface polymer grafting in concentrated and nonreactive aqueous polymer solutions.
Journal of the American Chemical Society 2010;132(10):3423-30.
2010: Oded Kleifeld; Alain Doucet; Ulrich auf dem Keller; Anna Prudova; Oliver Schilling; Rajesh K Kainthan; Amanda E Starr; Leonard J Foster; Jayachandran N Kizhakkedathu; Christopher M Overall
Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products.
Nature biotechnology 2010;28(3):281-8.
2010: Yuquan Zou; Po-Ying J Yeh; Nicholas A A Rossi; Donald E Brooks; Jayachandran N Kizhakkedathu
Nonbiofouling polymer brush with latent aldehyde functionality as a template for protein micropatterning.
Biomacromolecules 2010;11(1):284-93.
2009: Jayachandran N Kizhakkedathu; Johan Janzen; Yevgeniya Le; Rajesh Kumar Kainthan; Donald E Brooks
Poly(oligo(ethylene glycol)acrylamide) brushes by surface initiated polymerization: effect of macromonomer chain length on brush growth and protein adsorption from blood plasma.
Langmuir : the ACS journal of surfaces and colloids 2009;25(6):3794-801.
2009: Nicholas A A Rossi; Ibrahim Mustafa; John K Jackson; Helen M Burt; Sonja A Horte; Mark D Scott; Jayachandran N Kizhakkedathu
In vitro chelating, cytotoxicity, and blood compatibility of degradable poly(ethylene glycol)-based macromolecular iron chelators.
Biomaterials 2009;30(4):638-48.
2008: Po Ying Yeh; Yevgeniya Le; Jayachandran N Kizhakkedathu; Mu Chiao
An investigation of vibration-induced protein desorption mechanism using a micromachined membrane and PZT plate.
Biomedical microdevices 2008;10(5):701-8.
2008: Po-Ying J Yeh; Rajesh K Kainthan; Yuquan Zou; Mu Chiao; Jayachandran N Kizhakkedathu
Self-assembled monothiol-terminated hyperbranched polyglycerols on a gold surface: a comparative study on the structure, morphology, and protein adsorption characteristics with linear poly(ethylene glycol)s.
Langmuir : the ACS journal of surfaces and colloids 2008;24(9):4907-16.
2008: Rajesh Kumar Kainthan; Johan Janzen; Jayachandran N Kizhakkedathu; Dana V Devine; Donald E Brooks
Hydrophobically derivatized hyperbranched polyglycerol as a human serum albumin substitute.
Biomaterials 2008;29(11):1693-704.
2007: Bryan R Coad; Jayachandran N Kizhakkedathu; Charles A Haynes; Donald E Brooks
Synthesis of novel size exclusion chromatography support by surface initiated aqueous atom transfer radical polymerization.
Langmuir : the ACS journal of surfaces and colloids 2007;23(23):11791-803.
2007: Po-Ying J Yeh; Jayachandran N Kizhakkedathu; John D Madden; Mu Chiao
Electric field and vibration-assisted nanomolecule desorption and anti-biofouling for biosensor applications.
Colloids and surfaces. B, Biointerfaces 2007;59(1):67-73.
2007: Bryan R Coad; Bradley M Steels; Jayachandran N Kizhakkedathu; Donald E Brooks; Charles A Haynes
The influence of grafted polymer architecture and fluid hydrodynamics on protein separation by entropic interaction chromatography.
Biotechnology and bioengineering 2007;97(3):574-87.
2006: Rajesh Kumar Kainthan; Muthiah Gnanamani; MUNIA gaNGULI; Tanay Ghosh; Donald E Brooks; Souvik Maiti; Jayachandran N Kizhakkedathu
Blood compatibility of novel water soluble hyperbranched polyglycerol-based multivalent cationic polymers and their interaction with DNA.
Biomaterials 2006;27(31):5377-90.
2006: Jameel Ahmad Khan; Rajesh Kumar Kainthan; MUNIA gaNGULI; Jayachandran N Kizhakkedathu; Yogendra Singh; Souvik Maiti
Water soluble nanoparticles from PEG-based cationic hyperbranched polymer and RNA that protect RNA from enzymatic degradation.
Biomacromolecules 2006;7(5):1386-8.
2005: Jayachandran N Kizhakkedathu; CK Nisha; Sunkara V Manorama; Souvik Maiti
Water-soluble nanoparticles from random copolymer and oppositely charged surfactant, 3a. Nanoparticles of poly(ethylene glycol)-based cationic random copolymer and fatty acid salts.
Macromolecular bioscience 2005;5(6):549-58.
2004: CK Nisha; Sunkara V Manorama; Jayachandran N Kizhakkedathu; Souvik Maiti
Water-soluble complexes from random copolymer and oppositely charged surfactant. 2. Complexes of poly(ethylene glycol)-based cationic random copolymer and bile salts.
Langmuir : the ACS journal of surfaces and colloids 2004;20(20):8468-75.
2004: Diane Goodman; Jayachandran N Kizhakkedathu; Donald E Brooks
Evaluation of an atomic force microscopy pull-off method for measuring molecular weight and polydispersity of polymer brushes: effect of grafting density.
Langmuir : the ACS journal of surfaces and colloids 2004;20(15):6238-45.
2004: Diane Goodman; Jayachandran N Kizhakkedathu; Donald E Brooks
Molecular weight and polydispersity estimation of adsorbing polymer brushes by atomic force microscopy.
Langmuir : the ACS journal of surfaces and colloids 2004;20(8):3297-303.
2004: CK Nisha; Sunkara V Manorama; MUNIA gaNGULI; Souvik Maiti; Jayachandran N Kizhakkedathu
Complexes of poly(ethylene glycol)-based cationic random copolymer and calf thymus DNA: a complete biophysical characterization.
Langmuir : the ACS journal of surfaces and colloids 2004;20(6):2386-96.
2004: Diane Goodman; Jayachandran N Kizhakkedathu; Donald E Brooks
Attractive bridging interactions in dense polymer brushes in good solvent measured by atomic force microscopy.
Langmuir : the ACS journal of surfaces and colloids 2004;20(6):2333-40.
2004: Johan Janzen; Yevgeniya Le; Jayachandran N Kizhakkedathu; Donald E Brooks
Plasma protein adsorption to surfaces grafted with dense homopolymer and copolymer brushes containing poly(N-isopropylacrylamide).
Journal of biomaterials science. Polymer edition 2004;15(9):1121-35.