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Wolfram Klapper

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Bettina R Bonn; Andishe Attarbaschi; Gabriele Escherich; Wolfram Klapper; David Krieger; Felix Niggli; Ilske Oschlies; Alfred Reiter; Marius Rohde; Grazyna Wrobel; Martin Zimmermann; Birgit Burkhardt
Incidence and prognostic relevance of genetic variations in T-cell lymphoblastic lymphoma in childhood and adolescence.
Heike Horn; Michael Hummel; Wolfram Klapper; Markus Loeffler; Peter Möller; German Ott; Michael Pfreundschuh; Andreas Rosenwald; Christopher Schmelter; Norbert Schmitz; Reiner Siebert; Harald Stein; Lorenz Trümper; Marita Ziepert; Thomas F E Barth; Claudia Becher; Heinz-Wolfram Bernd; Sergio B Cogliatti; Alfred C Feller; Martin-Leo Hansmann
MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma.
Wolfram Klapper; K Koch; U Mechler; C Borck; E Fuhry; Reiner Siebert
Lymphoma 'type K.'-in memory of Karl Lennert (1921-2012).

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All Publications

2013: Bettina R Bonn; Andishe Attarbaschi; Gabriele Escherich; Wolfram Klapper; David Krieger; Felix Niggli; Ilske Oschlies; Alfred Reiter; Marius Rohde; Grazyna Wrobel; Martin Zimmermann; Birgit Burkhardt
Incidence and prognostic relevance of genetic variations in T-cell lymphoblastic lymphoma in childhood and adolescence.
Blood 2013;121(16):3153-60.
2013: Heike Horn; Michael Hummel; Wolfram Klapper; Markus Loeffler; Peter Möller; German Ott; Michael Pfreundschuh; Andreas Rosenwald; Christopher Schmelter; Norbert Schmitz; Reiner Siebert; Harald Stein; Lorenz Trümper; Marita Ziepert; Thomas F E Barth; Claudia Becher; Heinz-Wolfram Bernd; Sergio B Cogliatti; Alfred C Feller; Martin-Leo Hansmann
MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma.
Blood 2013;121(12):2253-63.
2013: Wolfram Klapper; K Koch; U Mechler; C Borck; E Fuhry; Reiner Siebert
Lymphoma 'type K.'-in memory of Karl Lennert (1921-2012).
Leukemia 2013;27(3):519-21.
2013: Benedicta E Beck-Broichsitter; Andreas Günther; Wolfram Klapper; Jörg Wiltfang; Stephan T Becker
Gingival ulceration and exposed bone.
Oral surgery, oral medicine, oral pathology and oral radiology 2013;115(3):288-92.
2013: Itziar Salaverria; Carsten Schwaenen; Monika Szczepanowski; Lorenz Trümper; Swen Wessendorf; Thorsten Zenz; Norbert Arnold; Baudis Michael; Susanne Bens; Birgit Burkhardt; Africa García-Orad; Wolfram Klapper; Markus Kreuz; Jasmin Lisfeld; Idoia Martin-Guerrero; Ilske Oschlies; Michael Pfreundschuh; Reiner Siebert
High resolution copy number analysis of IRF4 translocation-positive diffuse large B-cell and follicular lymphomas.
Genes, chromosomes & cancer 2013;52(2):150-5.
2013: Ibrahim Alkatout; Maret Bauer; Walter Jonat; Antonia Wenners; Meike Wiedermann; Wolfram Klapper
Transcription factors associated with epithelial-mesenchymal transition and cancer stem cells in the tumor centre and margin of invasive breast cancer.
Experimental and molecular pathology 2013;94(1):168-73.
2013: Nadine Wilsdorf; Anne-Margret Wingen; Ilske Oschlies; Lars Pape; Martin Pohl; Thomas F Schulz; Burkhard Tönshoff; Ulrich Baumann; Jana Diestelhorst; Britta Eiz-Vesper; Cornelia Henke-Gendo; Britta Höcker; Kais Hussein; Wolfram Klapper; Christoph Klein; Hans Kreipe; Britta Maecker-Kolhoff
EBV-specific T-cell immunity in pediatric solid organ graft recipients with posttransplantation lymphoproliferative disease.
Transplantation 2013;95(1):247-55.
2013: Ilske Oschlies; Alfred Reiter; Reiner Siebert; Ingrid Simonitsch-Klupp; Markus Stücker; Marianne Tinguely; Laurence Brugières; Emanuele S G d'Amore; Ulrika Hansson; Konnie Hebeda; Wolfram Klapper; Laurence Lamant; Marie-Cecile Ledeley; Jasmin Lisfeld; Jadwiga Maldyk; Leonhard Müllauer; Atsuko Nakazawa; Willi Woessmann
ALK-positive anaplastic large cell lymphoma limited to the skin: clinical, histopathological and molecular analysis of 6 pediatric cases. A report from the ALCL99 study.
Haematologica 2013;98(1):50-6.
2012: Karoline Koch; German Ott; Andreas Rosenwald; Michael Unterhalt; Marianne Engelhard; Martin L Hansmann; Wolfgang Hiddemann; Eva Hoster; Wolfram Klapper
The composition of the microenvironment in follicular lymphoma is associated with the stage of the disease.
Human pathology 2012;43(12):2274-81.
2012: Enrico Tiacci; Carel J M van Noesel; Wolfram Klapper; Ralf Küppers; Gunhild Mechtersheimer; Verena Brune; Claudia Döring; Brunangelo Falini; Martin-Leo Hansmann
Analyzing primary Hodgkin and Reed-Sternberg cells to capture the molecular and cellular pathogenesis of classical Hodgkin lymphoma.
Blood 2012;120(23):4609-20.
2012: Birte Malaika Overbeck; Reiner Siebert; Ole Ammerpohl; Wolfram Klapper; Jose I Martin-Subero; Maciej Giefing
ETS1 encoding a transcription factor involved in B-cell differentiation is recurrently deleted and down-regulated in classical Hodgkin's lymphoma.
Haematologica 2012;97(10):1612-4.
2012: Neus Masqué-Soler; Monika Szczepanowski; Christian Vokuhl; Gabriele Calaminus; Jochen Haag; Ivo Leuschner; Wolfram Klapper
Absence of BRAF mutation in pediatric and adolescent germ cell tumors indicate biological differences to adult tumors.
Pediatric blood & cancer 2012;59(4):732-5.
2012: Claudia Otto; Julia Richter; Matthias Schlesner; Reiner Siebert; Inga Vater; Stefan Gesk; Maciej Giefing; Martin-Leo Hansmann; Wolfram Klapper; Anne Massow; Ralf Küppers
Genetic lesions of the TRAF3 and MAP3K14 genes in classical Hodgkin lymphoma.
British journal of haematology 2012;157(6):702-8.
2012: Jan Suthaus; Van S Tompkins; Giovanna Tosato; Jürgen Scheller; Christiane Stuhlmann-Laeisz; Siegfried Janz; Wolfram Klapper; Timothy R Rosean; Stefan Rose-John
HHV-8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice.
Blood 2012;119(22):5173-81.
2012: Wolfram Klapper; Ilske Oschlies
[Specifics of histopathological and genetical diagnosis and classification of lymphomas in children and adolescents].
Klinische Pädiatrie 2012;224(3):183-90.
2012: Itziar Salaverria; Monika Szczepanowski; Takashi Akasaka; Birgit Burkhardt; Christine Damm-Welk; Martin J S Dyer; Stefan Gesk; Lana Harder; Wolfram Klapper; Ilske Oschlies; Reiner Siebert
The CBFA2T3/ACSF3 locus is recurrently involved in IGH chromosomal translocation t(14;16)(q32;q24) in pediatric B-cell lymphoma with germinal center phenotype.
Genes, chromosomes & cancer 2012;51(4):338-43.
2012: Heiner Zimmermann; Ioannis Anagnostopoulos; Martin Dreyling; Susanne Fink; Barbara Gärtner; Ingeborg A Hauser; Wolfram Klapper; Michael Kneba; Hans Lehmkuhl; Hans H Neumayer; Ilske Oschlies; Christiane Pott; Hanno Riess; Ralf Ulrich Trappe
Plasmablastic posttransplant lymphoma: cytogenetic aberrations and lack of Epstein-Barr virus association linked with poor outcome in the prospective German Posttransplant Lymphoproliferative Disorder Registry.
Transplantation 2012;93(5):543-50.
2012: Wolfram Klapper; Christian W Kohler; Markus Kreuz; Markus Loeffler; Shoji Pellissery; Itziar Salaverria; Carsten Schwänen; Reiner Siebert; Rainer Spang; Monika Szczepanowski; Lorenz Trümper; Swen Wessendorf; Wilhelm Woessmann; Birgit Burkhardt; Dirk Hasenclever; Michael Hummel
Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma.
Blood 2012;119(8):1882-7.
2011: Sylvia Hartmann; Wolfram Klapper; Karoline Koch; Penelope Korkolopoulou; Teresa Marafioti; Efstratios Patsouris; Pier Paolo Piccaluga; Stefano Pileri; Claudio Agostinelli; Martin-Leo Hansmann
Revising the historical collection of epithelioid cell-rich lymphomas of the Kiel Lymph Node Registry: what is Lennert's lymphoma nowadays?
Histopathology 2011;59(6):1173-82.
2011: Willi Woessmann; Martin Zimmermann; Claudia Rossig; Andishe Attarbaschi; Birgit Burkhardt; Wolfram Klapper; Bernhard Kremens; Peter Lang; Meike Lenhard; Georg Mann; Ilske Oschlies; Alfred Reiter
Relapsed or refractory anaplastic large-cell lymphoma in children and adolescents after Berlin-Frankfurt-Muenster (BFM)-type first-line therapy: a BFM-group study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(22):3065-71.
2011: Wolfram Klapper
Histopathology of mantle cell lymphoma.
Seminars in hematology 2011;48(3):148-54.
2011: Karoline Koch; Wolfram Klapper
Endogenous interferon α therapy in follicular lymphoma?
Leukemia & lymphoma 2011;52(7):1168-9.
2011: Gunnar Jacobs; Wolfram Klapper; Markus Kosmahl; Ruta Kwiatkowski; Ralph Lucius; Stephan Ott; Wolfgang Fischbach; Ulrich R Fölsch; Andre Franke; Jochen Hampe; Stephan Hellmig; Klaus Huse; Stefan Schreiber; Andrea Titz; Philip Rosenstiel
Polymorphisms in the 3'-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma.
Haematologica 2011;96(7):987-95.
2011: Ilske Oschlies; Anna Porwit; Alfred Reiter; Ana-Iris Schmatz; Marianne Tinguely; Andrew Wotherspoon; Martin Zimmermann; Dimitry Abramov; Birgit Burkhardt; Catherine Chassagne-Clement; Emanuele S G d'Amore; Ulrika Hansson; Konnie Hebeda; Roman Kodet; Jadwiga Maldyk; Keith Mc Carthy; Leonhard Müllauer; Wolfram Klapper
Diagnosis and immunophenotype of 188 pediatric lymphoblastic lymphomas treated within a randomized prospective trial: experiences and preliminary recommendations from the European childhood lymphoma pathology panel.
The American journal of surgical pathology 2011;35(6):836-44.
2011: Wolfram Klapper
Pathobiology and diagnosis of follicular lymphoma.
Seminars in diagnostic pathology 2011;28(2):146-60.
2011: Mi Kyung Jin; Eva Hoster; Martin Dreyling; Michael Unterhalt; Wolfgang Hiddemann; Wolfram Klapper
Follicular dendritic cells in follicular lymphoma and types of non-Hodgkin lymphoma show reduced expression of CD23, CD35 and CD54 but no association with clinical outcome.
Histopathology 2011;58(4):586-92.
2011: Ilske Oschlies; Birgit Burkhardt; Itziar Salaverria; Andreas Rosenwald; Emanuele S G d'Amore; Monika Szczepanowski; Karoline Koch; Martin L Hansmann; Harald Stein; Peter Möller; Alfred Reiter; Martin Zimmermann; Angelo Rosolen; Reiner Siebert; Elaine S Jaffe; Wolfram Klapper
Clinical, pathological and genetic features of primary mediastinal large B-cell lymphomas and mediastinal gray zone lymphomas in children.
Haematologica 2011;96(2):262-8.
2011: Leandro Cerchietti; Christine Damm-Welk; Inga Vater; Wolfram Klapper; Lana Harder; Christiane Pott; Shao Ning Yang; Alfred Reiter; Reiner Siebert; Ari Melnick; Willi Woessmann
Inhibition of anaplastic lymphoma kinase (ALK) activity provides a therapeutic approach for CLTC-ALK-positive human diffuse large B cell lymphomas.
PloS one 2011;6(4):e18436.
2011: Birgit Burkhardt; Ilske Oschlies; Wolfram Klapper; Martin Zimmermann; Willi Woessmann; A Meinhardt; Eva Landmann; Andishe Attarbaschi; Felix Niggli; Martin Schrappe; Alfred Reiter
Non-Hodgkin's lymphoma in adolescents: experiences in 378 adolescent NHL patients treated according to pediatric NHL-BFM protocols.
Leukemia 2011;25(1):153-60.
2010: German Ott; Marita Ziepert; Wolfram Klapper; Heike Horn; Monika Szczepanowski; Heinz-Wolfram Bernd; Christoph Thorns; Alfred C Feller; Dido Lenze; Michael Hummel; Harald Stein; Hans Konrad Müller-Hermelink; Matthias Frank; Martin-Leo Hansmann; Thomas F E Barth; Peter Möller; Sergio B Cogliatti; Michael Pfreundschuh; Norbert Schmitz; Lorenz Trümper; Markus Loeffler; Andreas Rosenwald
Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL.
Blood 2010;116(23):4916-25.
2010: René Scholtysik; Markus Kreuz; Wolfram Klapper; Birgit Burkhardt; Alfred C Feller; Michael Hummel; Markus Loeffler; Maciej Rosolowski; Carsten Schwaenen; Rainer Spang; Harald Stein; Christoph Thorns; Lorenz Trümper; Inga Vater; Swen Wessendorf; Thorsten Zenz; Reiner Siebert; Ralf Küppers
Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis.
Haematologica 2010;95(12):2047-55.
2010: Inga Nagel; Monika Szczepanowski; José I Martín-Subero; Lana Harder; Takashi Akasaka; Ole Ammerpohl; Evelyne Callet-Bauchu; Randy D Gascoyne; Stefan Gesk; Doug Horsman; Wolfram Klapper; Aneela Majid; Jose A Martinez-Climent; Stephan Stilgenbauer; Holger Tönnies; Martin J S Dyer; Reiner Siebert
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies.
Blood 2010;116(8):1317-20.
2010: Andrea Meinhardt; Birgit Burkhardt; Martin Zimmermann; Arndt Borkhardt; Udo Kontny; Thomas Klingebiel; Frank Berthold; Gritta Janka-Schaub; Christoph Klein; Edita Kabickova; Wolfram Klapper; Andishe Attarbaschi; Martin Schrappe; Alfred Reiter
Phase II window study on rituximab in newly diagnosed pediatric mature B-cell non-Hodgkin's lymphoma and Burkitt leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(19):3115-21.
2010: Ilske Oschlies; Itziar Salaverria; Friederike Mahn; Andrea Meinhardt; Martin Zimmermann; Wilhelm Woessmann; Birgit Burkhardt; Stefan Gesk; Matthias Krams; Alfred Reiter; Reiner Siebert; Wolfram Klapper
Pediatric follicular lymphoma--a clinico-pathological study of a population-based series of patients treated within the Non-Hodgkin's Lymphoma--Berlin-Frankfurt-Munster (NHL-BFM) multicenter trials.
Haematologica 2010;95(2):253-9.
2009: Heinz-Wolfram Bernd; Marita Ziepert; Christoph Thorns; Wolfram Klapper; Hans-Heinrich Wacker; Michael Hummel; Harald Stein; Martin-Leo Hansmann; German Ott; Andreas Rosenwald; Hans Konrad Müller-Hermelink; Thomas F E Barth; Peter Möller; Sergio B Cogliatti; Michael Pfreundschuh; Norbert Schmitz; Lorenz Trümper; Silvia Höller; Markus Loeffler; Alfred C Feller
Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials.
Haematologica 2009;94(11):1569-80.
2009: S Eckerle; V Brune; C Döring; Enrico Tiacci; V Bohle; Christer Sundström; R Kodet; Marco Paulli; B Falini; Wolfram Klapper; A B Chaubert; Klaus Willenbrock; D Metzler; Andreas Bräuninger; Ralf Küppers; Martin-Leo Hansmann
Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma.
Leukemia 2009;23(11):2129-38.
2009: Christine Damm-Welk; Wolfram Klapper; Ilske Oschlies; Stefan Gesk; Silja Röttgers; Jutta Bradtke; Reiner Siebert; Alfred Reiter; Willi Woessmann
Distribution of NPM1-ALK and X-ALK fusion transcripts in paediatric anaplastic large cell lymphoma: a molecular-histological correlation.
British journal of haematology 2009;146(3):306-9.
2009: Wolfram Klapper; Philip M Kluin; Roman Kodet; Yuri A Krivolapov; Christoph Loddenkemper; Peter Möller; Konrad Müller-Hermelink; Ilske Oschlies; German Ott; Stefano Pileri; Elisabeth Ralfkiaer; Andreas Rosenwald; Grzegorz Rymkiewicz; Harald Stein; Michael Unterhalt; Jeroen van der Laak; Johan H van Krieken; Hans Heinrich Wacker; Thomas E F Barth; Françoise Berger; Heinz-Wolfram Bernd; José Cabeçadas; Elias Campo; Sergio B Cogliatti; Olaf Determann; Martin Dreyling; Martin-Leo Hansmann; Wolfgang Hiddemann; Eva Hoster
Ki-67 as a prognostic marker in mantle cell lymphoma-consensus guidelines of the pathology panel of the European MCL Network.
Journal of hematopathology 2009;2(2):103-11.
2009: Inga Nagel; Takashi Akasaka; Wolfram Klapper; Stefan Gesk; Sebastian Böttcher; Matthias Ritgen; Lana Harder; Michael Kneba; Martin J S Dyer; Reiner Siebert
Identification of the gene encoding cyclin E1 (CCNE1) as a novel IGH translocation partner in t(14;19)(q32;q12) in diffuse large B-cell lymphoma.
Haematologica 2009;94(7):1020-3.
2009: Stephan Hellmig; Tobias Bartscht; Wolfgang Fischbach; Stephan Johannes Ott; Philip Rosenstiel; Wolfram Klapper; Ulrich Robert Fölsch; Stefan Schreiber
Germline variations of the MALT1 gene as risk factors in the development of primary gastric B-cell lymphoma.
European journal of cancer (Oxford, England : 1990) 2009;45(10):1865-70.
2009: Roland Schmitz; Martin-Leo Hansmann; Verena Bohle; Jose Ignacio Martin-Subero; Sylvia Hartmann; Gunhild Mechtersheimer; Wolfram Klapper; Inga Vater; Maciej Giefing; Stefan Gesk; Jens Stanelle; Reiner Siebert; Ralf Küppers
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma.
The Journal of experimental medicine 2009;206(5):981-9.
2009: Inga Vater; Florian Wagner; Markus Kreuz; Hilmar Berger; José I Martín-Subero; Christiane Pott; Jose A Martinez-Climent; Wolfram Klapper; Kristina Krause; Martin J S Dyer; Stefan Gesk; Lana Harder; Alberto Zamò; Martin Dreyling; Dirk Hasenclever; Norbert Arnold; Reiner Siebert
GeneChip analyses point to novel pathogenetic mechanisms in mantle cell lymphoma.
British journal of haematology 2009;144(3):317-31.
2009: Christian Buske; Eva Hoster; Martin Dreyling; Hartmut Eimermacher; Hannes Wandt; Bernd Metzner; R Fuchs; J Bittenbring; B Woermann; K Hohloch; G Hess; Wolf-Dieter Ludwig; J Schimke; S Schmitz; Michael Kneba; Maximilian Reiser; U Graeven; Wolfram Klapper; Michael Unterhalt; Wolfgang Hiddemann
The addition of rituximab to front-line therapy with CHOP (R-CHOP) results in a higher response rate and longer time to treatment failure in patients with lymphoplasmacytic lymphoma: results of a randomized trial of the German Low-Grade Lymphoma Study Group (GLSG).
Leukemia 2009;23(1):153-61.
2008: Stephan T Becker; Jörg Wiltfang; Wolfram Klapper; Roland Repp; Nektarios Sinis; Patrick H Warnke
Massive swelling of the cervical region: an uncommon manifestation of B cell chronic lymphocytic leukemia.
Oral and maxillofacial surgery 2008;12(4):205-8.
2008: Natalia Szymanowska; Wolfram Klapper; Stefan Gesk; Ralf Küppers; José I Martín-Subero; Reiner Siebert
BCL2 and BCL3 are recurrent translocation partners of the IGH locus.
Cancer genetics and cytogenetics 2008;186(2):110-4.
2008: Sylvia Hartmann; Jose I Martin-Subero; Stefan Gesk; Julia Hüsken; Maciej Giefing; Inga Nagel; Jennifer Riemke; Andreas Chott; Wolfram Klapper; Marie Parrens; Jean-Philippe Merlio; Ralf Küppers; Andreas Bräuninger; Reiner Siebert; Martin-Leo Hansmann
Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma by array-based comparative genomic hybridization.
Haematologica 2008;93(9):1318-26.
2008: Wolfram Klapper; Monika Szczepanowski; Birgit Burkhardt; Hilmar Berger; Maciej Rosolowski; Stefan Bentink; Carsten Schwaenen; Swen Wessendorf; Rainer Spang; Peter Möller; Martin-Leo Hansmann; Heinz-Wolfram Bernd; German Ott; Michael Hummel; Harald Stein; Markus Loeffler; Lorenz Trümper; Martin Zimmermann; Alfred Reiter; Reiner Siebert
Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials.
Blood 2008;112(4):1374-81.
2008: Alfred Reiter; Wolfram Klapper
Recent advances in the understanding and management of diffuse large B-cell lymphoma in children.
British journal of haematology 2008;142(3):329-47.
2008: Wolfram Klapper; Matthias Böhm; Reiner Siebert; Karl Lennert
Morphological variability of lymphohistiocytic variant of anaplastic large cell lymphoma (former lymphohistiocytic lymphoma according to the Kiel classification).
Virchows Archiv : an international journal of pathology 2008;452(6):599-605.
2008: Judith Dierlamm; Eva M Murga Penas; Stefan Bentink; Swen Wessendorf; Hilmar Berger; Michael Hummel; Wolfram Klapper; Dido Lenze; Andreas Rosenwald; Eugenia Haralambieva; German Ott; Sergio B Cogliatti; Peter Möller; Carsten Schwaenen; Harald Stein; Markus Loeffler; Rainer Spang; Lorenz Trümper; Reiner Siebert
Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.
Haematologica 2008;93(5):688-96.
2008: Birgit Burkhardt; Anja Moericke; Wolfram Klapper; Franziska Greene; Janina Salzburg; Christine Damm-Welk; Martin Zimmermann; Konstantin Strauch; Wolf-Dieter Ludwig; Martin Schrappe; Alfred Reiter
Pediatric precursor T lymphoblastic leukemia and lymphoblastic lymphoma: Differences in the common regions with loss of heterozygosity at chromosome 6q and their prognostic impact.
Leukemia & lymphoma 2008;49(3):451-61.
2008: Olaf Determann; Eva Hoster; German Ott; Heinz Wolfram Bernd; Christoph Loddenkemper; Martin Leo Hansmann; Thomas E F Barth; Michael Unterhalt; Wolfgang Hiddemann; Martin Dreyling; Wolfram Klapper
Ki-67 predicts outcome in advanced-stage mantle cell lymphoma patients treated with anti-CD20 immunochemotherapy: results from randomized trials of the European MCL Network and the German Low Grade Lymphoma Study Group.
Blood 2008;111(4):2385-7.
2008: Eva Hoster; Martin Dreyling; Wolfram Klapper; Christian Gisselbrecht; Achiel Van Hoof; Hanneke C Kluin-Nelemans; Michael Pfreundschuh; Marcel Reiser; Bernd Metzner; Hermann Einsele; Norma Peter; Wolfram Jung; Bernhard Wörmann; Wolf-Dieter Ludwig; Ulrich Dührsen; Hartmut Eimermacher; Hannes Wandt; Joerg Hasford; Wolfgang Hiddemann; Michael Unterhalt
A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma.
Blood 2008;111(2):558-65.
2007: Georg Mann; Andishe Attarbaschi; Birgit Burkhardt; Felix Niggli; Wolfram Klapper; Wolf-Dieter Ludwig; Martin Schrappe; Martin Zimmermann; Helmut Gadner; Alfred Reiter
Clinical characteristics and treatment outcome of infants with non-Hodgkin lymphoma.
British journal of haematology 2007;139(3):443-9.
2007: Monika Szczepanowski; Sabine Adam-Klages; Marie-Luise Kruse; Marc Pollmann; Wolfram Klapper; Reza Parwaresch; Hans-Juergen Heidebrecht
Regulation of repp86 stability by human Siah2.
Biochemical and biophysical research communications 2007;362(2):485-90.
2007: Liya Ma; Gaixiang Xu; Anna Sotnikova; Monika Szczepanowski; Maciej Giefing; Kristina Krause; Matthias Krams; Reiner Siebert; Jie Jin; Wolfram Klapper
Loss of expression of LyGDI (ARHGDIB), a rho GDP-dissociation inhibitor, in Hodgkin lymphoma.
British journal of haematology 2007;139(2):217-23.
2007: Janina Salzburg; Birgit Burkhardt; Martin Zimmermann; Olga Wachowski; Willi Woessmann; Ilske Oschlies; Wolfram Klapper; Hans-Heinrich Wacker; Wolf-Dieter Ludwig; Felix Niggli; Georg Mann; Helmut Gadner; Hansjörg Riehm; Martin Schrappe; Alfred Reiter
Prevalence, clinical pattern, and outcome of CNS involvement in childhood and adolescent non-Hodgkin's lymphoma differ by non-Hodgkin's lymphoma subtype: a Berlin-Frankfurt-Munster Group Report.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(25):3915-22.
2007: Wolfram Klapper; Eva Hoster; Lars Rölver; Carsten Schrader; Dirk Janssen; Markus Tiemann; Heinz-Wolfram Bernd; Olaf Determann; Martin-Leo Hansmann; Peter Möller; Alfred Feller; Harald Stein; Hans-Heinrich Wacker; Martin Dreyling; Michael Unterhalt; Wolfgang Hiddemann; German Ott
Tumor sclerosis but not cell proliferation or malignancy grade is a prognostic marker in advanced-stage follicular lymphoma: the German Low Grade Lymphoma Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(22):3330-6.
2007: Christine Damm-Welk; Kerstin Busch; Birgit Burkhardt; Jutta Schieferstein; Susanne Viehmann; Ilske Oschlies; Wolfram Klapper; Martin Zimmermann; Jochen Harbott; Alfred Reiter; Willi Woessmann
Prognostic significance of circulating tumor cells in bone marrow or peripheral blood as detected by qualitative and quantitative PCR in pediatric NPM-ALK-positive anaplastic large-cell lymphoma.
Blood 2007;110(2):670-7.
2007: José I Martín-Subero; Rachel E Ibbotson; Wolfram Klapper; L Michaux; Evelyne Callet-Bauchu; F Berger; María J Calasanz; C De Wolf-Peeters; Martin J S Dyer; Pascale Felman; Anne Gardiner; Randy D Gascoyne; Stefan Gesk; Lana Harder; D E Horsman; Michael Kneba; Ralf Küppers; A Majid; Nilima Parry-Jones; Matthias Ritgen; M Salido; F Solé; G Thiel; Hans-Heinrich Wacker; David Oscier; Iwona Wlodarska; Reiner Siebert
A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation.
Leukemia 2007;21(7):1532-44.
2007: Christoph Renné; Nora Hinsch; Klaus Willenbrock; Michael Fuchs; Wolfram Klapper; Andreas Engert; Ralf Küppers; Martin-Leo Hansmann; Andreas Bräuninger
The aberrant coexpression of several receptor tyrosine kinases is largely restricted to EBV-negative cases of classical Hodgkin's lymphoma.
International journal of cancer. Journal international du cancer 2007;120(11):2504-9.
2007: Dirk Janssen; Regina Fölster-Holst; Dieter Harms; Wolfram Klapper
Clonality in juvenile xanthogranuloma.
The American journal of surgical pathology 2007;31(5):812-3.
2007: Motohiro Kojima; Bence Sipos; Wolfram Klapper; Olaf Frahm; Hans-Christian Knuth; Akio Yanagisawa; GIUSEPPE ZAMBONI; Toshio Morohoshi; Günter Klöppel
Autoimmune pancreatitis: frequency, IgG4 expression, and clonality of T and B cells.
The American journal of surgical pathology 2007;31(4):521-8.
2007: Christoph Renné; Klaus Willenbrock; Jose I Martin-Subero; Nora Hinsch; C Döring; Enrico Tiacci; Wolfram Klapper; P Möller; Ralf Küppers; Martin-Leo Hansmann; Reiner Siebert; Andreas Bräuninger
High expression of several tyrosine kinases and activation of the PI3K/AKT pathway in mediastinal large B cell lymphoma reveals further similarities to Hodgkin lymphoma.
Leukemia 2007;21(4):780-7.
2007: Daphne de Jong; Andreas Rosenwald; Mukesh Chhanabhai; Philippe Gaulard; Wolfram Klapper; Abigail Lee; Birgitta Sander; Christoph Thorns; Elias Campo; Thierry Molina; Andrew Norton; Anton Hagenbeek; Sandra J Horning; Andrew Lister; John M M Raemaekers; Randy D Gascoyne; Gilles SALLES; Edie Weller
Immunohistochemical prognostic markers in diffuse large B-cell lymphoma: validation of tissue microarray as a prerequisite for broad clinical applications--a study from the Lunenburg Lymphoma Biomarker Consortium.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(7):805-12.
2007: Wolfram Klapper; Hans-Heinrich Wacker
[Follicular and mantle cell lymphoma. Extranodal involvement of primarily nodal indolent B-cell lymphomas].
Der Pathologe 2007;28(1):21-8.
2006: José I Martín-Subero; Wolfram Klapper; Anna Sotnikova; Evelyne Callet-Bauchu; Lana Harder; Christian Bastard; Roland Schmitz; Susanne Grohmann; Jorge Höppner; Jennifer Riemke; Thomas F E Barth; Françoise Berger; Heinz-Wolfram Bernd; Alexander Claviez; Stefan Gesk; Georgiy A Frank; Irina B Kaplanskaya; Peter Möller; Reza Parwaresch; Thomas Rüdiger; Harald Stein; Ralf Küppers; Martin-Leo Hansmann; Reiner Siebert
Chromosomal breakpoints affecting immunoglobulin loci are recurrent in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma.
Cancer research 2006;66(21):10332-8.
2006: Stefan Gesk; Wolfram Klapper; José I Martín-Subero; Inga Nagel; Lana Harder; Kai Fu; Heinz-Wolfram Bernd; Dennis D Weisenburger; Reza Parwaresch; Reiner Siebert
A chromosomal translocation in cyclin D1-negative/cyclin D2-positive mantle cell lymphoma fuses the CCND2 gene to the IGK locus.
Blood 2006;108(3):1109-10.
2006: A Pachnio; Sebastian Dietrich; Wolfram Klapper; Andreas Humpe; Michael Schwake; Radislav Sedlacek; Martin Gramatzki; Christian Beck
Proliferation-based T-cell selection for immunotherapy and graft-versus-host-disease prophylaxis in the context of bone marrow transplantation.
Bone marrow transplantation 2006;38(2):157-67.
2006: Jose I Martin-Subero; Iwona Wlodarska; Christian Bastard; Jean-Michel Picquenot; Jorge Höppner; Maciej Giefing; Wolfram Klapper; Reiner Siebert
Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma.
Blood 2006;108(1):401-2; author reply 402-3.
2006: Wolfram Klapper; Monika Szczepanowski; Klaus Heidorn; Markus Müschen; Stefanie Liedtke; Anna Sotnikova; N S Andersen; Jobst Greeve; Reza Parwaresch
Immunoglobulin class-switch recombination occurs in mantle cell lymphomas.
The Journal of pathology 2006;209(2):250-7.
2006: Ilske Oschlies; Wolfram Klapper; Martin Zimmermann; Matthias Krams; Hans-Heinrich Wacker; Birgit Burkhardt; Lana Harder; Reiner Siebert; Alfred Reiter; Reza Parwaresch
Diffuse large B-cell lymphoma in pediatric patients belongs predominantly to the germinal-center type B-cell lymphomas: a clinicopathologic analysis of cases included in the German BFM (Berlin-Frankfurt-Munster) Multicenter Trial.
Blood 2006;107(10):4047-52.
2005: Bence Sipos; Motohiro Kojima; Katharina Tiemann; Wolfram Klapper; Marie-Luise Kruse; Holger Kalthoff; Bodo Schniewind; Juergen Tepel; Herbert Weich; Dontscho Kerjaschki; Günter Klöppel
Lymphatic spread of ductal pancreatic adenocarcinoma is independent of lymphangiogenesis.
The Journal of pathology 2005;207(3):301-12.
2005: Carsten Schrader; Dirk Janssen; Wolfram Klapper; Jens U Siebmann; Peter Meusers; Günter Brittinger; Michael Kneba; Markus Tiemann; Reza Parwaresch
Minichromosome maintenance protein 6, a proliferation marker superior to Ki-67 and independent predictor of survival in patients with mantle cell lymphoma.
British journal of cancer 2005;93(8):939-45.
2005: Markus Tiemann; Carsten Schrader; Wolfram Klapper; Martin Dreyling; Elias Campo; Andrew Norton; Francoise Berger; Philip M Kluin; German Ott; Stephano Pileri; Ennio Pedrinis; Alfred C Feller; Hartmut Merz; Dirk Janssen; Martin-Leo Hansmann; Han Krieken; Peter Möller; Harald Stein; Michael Unterhalt; Wolfgang Hiddemann; Reza Parwaresch
Histopathology, cell proliferation indices and clinical outcome in 304 patients with mantle cell lymphoma (MCL): a clinicopathological study from the European MCL Network.
British journal of haematology 2005;131(1):29-38.
2005: Stefan Gesk; R D Gascoyne; Bertram Schnitzer; Nasir A Bakshi; Dirk Janssen; Wolfram Klapper; José I Martín-Subero; Reza Parwaresch; R Siebert
ALK-positive diffuse large B-cell lymphoma with ALK-Clathrin fusion belongs to the spectrum of pediatric lymphomas.
Leukemia 2005;19(10):1839-40.
2005: Maren Ruhnke; Hendrik Ungefroren; Andreas K Nussler; Franz Martin; Marc Brulport; Wiebke Schormann; Jan G Hengstler; Wolfram Klapper; Karin Ulrichs; James A Hutchinson; Bernat Soria; Reza Parwaresch; Peter Heeckt; Bernd Kremer; Fred Fändrich
Differentiation of in vitro-modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cells.
Gastroenterology 2005;128(7):1774-86.
2004: Wolfram Klapper; Frank Moosig; Anna Sotnikova; W Qian; Johann O Schröder; Reza Parwaresch
Telomerase activity in B and T lymphocytes of patients with systemic lupus erythematosus.
Annals of the rheumatic diseases 2004;63(12):1681-3.
2004: Bence Sipos; Wolfram Klapper; Marie-Luise Kruse; Holger Kalthoff; Dontscho Kerjaschki; Günter Klöppel
Expression of lymphangiogenic factors and evidence of intratumoral lymphangiogenesis in pancreatic endocrine tumors.
The American journal of pathology 2004;165(4):1187-97.
2003: Anna Trauzold; Stefan Schmiedel; Bence Sipos; Hendrik Wermann; Sabine Westphal; Christian Röder; Wolfram Klapper; Alexander Arlt; Lasse Lehnert; Hendrik Ungefroren; Franz-Josef Johannes; Holger Kalthoff
PKCmu prevents CD95-mediated apoptosis and enhances proliferation in pancreatic tumour cells.
Oncogene 2003;22(55):8939-47.
2003: Wolfram Klapper; Matthias Krams; W Qian; Dirk Janssen; Reza Parwaresch
Telomerase activity in B-cell non-Hodgkin lymphomas is regulated by hTERT transcription and correlated with telomere-binding protein expression but uncoupled from proliferation.
British journal of cancer 2003;89(4):713-9.
2003: Jobst Greeve; Antje Philipsen; Kristina Krause; Wolfram Klapper; Klaus Heidorn; Brian E Castle; Joe Janda; Kenneth B Marcu; Reza Parwaresch
Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas.
Blood 2003;101(9):3574-80.
2001: G Bonatz; Sven O Frahm; Wolfram Klapper; Andreas Helfenstein; Klaus Heidorn; Walter Jonat; Guido Krupp; Reza Parwaresch; Pierre Rudolph
High telomerase activity is associated with cell cycle deregulation and rapid progression in endometrioid adenocarcinoma of the uterus.
Human pathology 2001;32(6):605-14.
2001: Wolfram Klapper; Reza Parwaresch; Guido Krupp
Telomere biology in human aging and aging syndromes.
Mechanisms of ageing and development 2001;122(7):695-712.
2000: Guido Krupp; Wolfram Klapper; Reza Parwaresch
Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation.
Cellular and molecular life sciences : CMLS 2000;57(3):464-86.
1998: G Bonatz; Wolfram Klapper; A Barthe; Klaus Heidorn; Walter Jonat; Guido Krupp; Reza Parwaresch
Analysis of telomerase expression and proliferative activity in the different layers of cyclic endometrium.
Biochemical and biophysical research communications 1998;253(2):214-21.
1998: Wolfram Klapper; K Kühne; KK Singh; Klaus Heidorn; Reza Parwaresch; Guido Krupp
Longevity of lobsters is linked to ubiquitous telomerase expression.
FEBS letters 1998;439(1-2):143-6.
1998: Wolfram Klapper; KK Singh; Klaus Heidorn; Reza Parwaresch; Guido Krupp
Regulation of telomerase activity in quiescent immortalized human cells.
Biochimica et biophysica acta 1998;1442(2-3):120-6.
1998: Wolfram Klapper; Klaus Heidorn; K Kühne; Reza Parwaresch; Guido Krupp
Telomerase activity in 'immortal' fish.
FEBS letters 1998;434(3):409-12.
1997: Guido Krupp; K Kühne; S Tamm; Wolfram Klapper; Klaus Heidorn; A Rott; Reza Parwaresch
Molecular basis of artifacts in the detection of telomerase activity and a modified primer for a more robust 'TRAP' assay.
Nucleic acids research 1997;25(4):919-21.