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David Klatzmann

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Geraldine Lescaille; Rodney Macedo; Fabien Pitoiset; Eric Tartour; Claude Baillou; Christophe Huret; David Klatzmann; François M Lemoine; Bertrand Bellier
Efficacy of DNA vaccines forming e7 recombinant retroviral virus-like particles for the treatment of human papillomavirus-induced cancers.
David Saadoun; Damien Sene; Benjamin Terrier; T Vazquez; F Joly; I Kang; David Klatzmann; C Massad; Eric Meffre; Lucile Musset; Michelle Rosenzwajg; J Bannock; P Benech; P Cacoub
Expansion of autoreactive unresponsive CD21-/low B cells in Sjögren's syndrome-associated lymphoproliferation.
Christophe Huret; David Klatzmann; Béatrice Levacher; Mathilde Miyalou; Olivia Bonduelle; Béhazine Combadière; Charlotte Dalba; Delphine Desjardins; Martin Amadoudji Zin; Bertrand Bellier
Recombinant retrovirus-derived virus-like particle-based vaccines induce hepatitis C virus-specific cellular and neutralizing immune responses in mice.

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2013: Geraldine Lescaille; Rodney Macedo; Fabien Pitoiset; Eric Tartour; Claude Baillou; Christophe Huret; David Klatzmann; François M Lemoine; Bertrand Bellier
Efficacy of DNA vaccines forming e7 recombinant retroviral virus-like particles for the treatment of human papillomavirus-induced cancers.
Human gene therapy 2013;24(5):533-44.
2013: David Saadoun; Damien Sene; Benjamin Terrier; T Vazquez; F Joly; I Kang; David Klatzmann; C Massad; Eric Meffre; Lucile Musset; Michelle Rosenzwajg; J Bannock; P Benech; P Cacoub
Expansion of autoreactive unresponsive CD21-/low B cells in Sjögren's syndrome-associated lymphoproliferation.
Arthritis and rheumatism 2013;65(4):1085-96.
2013: Christophe Huret; David Klatzmann; Béatrice Levacher; Mathilde Miyalou; Olivia Bonduelle; Béhazine Combadière; Charlotte Dalba; Delphine Desjardins; Martin Amadoudji Zin; Bertrand Bellier
Recombinant retrovirus-derived virus-like particle-based vaccines induce hepatitis C virus-specific cellular and neutralizing immune responses in mice.
Vaccine 2013;31(11):1540-7.
2013: Bertrand Bellier; David Klatzmann
Virus-like particle-based vaccines against hepatitis C virus infection.
Expert review of vaccines 2013;12(2):143-54.
2012: Soumia Touil; Charlotte Frédéric; David Klatzmann; Dan-Avi Landau; Philippe Le Corvoisier; Sébastien Maury; Michelle Rosenzwajg; José L Cohen
Depletion of T regulatory cells through selection of CD127-positive cells results in a population enriched in memory T cells: implications for anti-tumor cell therapy.
Haematologica 2012;97(11):1678-85.
2012: Benjamin Terrier; Nathalie Costedoat-Chalumeau; Marlène Garrido; Guillaume Geri; David Klatzmann; Lucile Musset; Michelle Rosenzwajg; David Saadoun; Patrice Cacoub
Interleukin 21 correlates with T cell and B cell subset alterations in systemic lupus erythematosus.
The Journal of rheumatology 2012;39(9):1819-28.
2012: Benjamin Terrier; Yves Allenbach; Olivier Benveniste; Wahiba Chaara; Nathalie Costedoat-Chalumeau; Pierre Fouret; Guillaume Geri; David Klatzmann; Lucile Musset; Michelle Rosenzwajg; David Saadoun; Adrien Six; Patrice Cacoub
Interleukin-21 modulates Th1 and Th17 responses in giant cell arteritis.
Arthritis and rheumatism 2012;64(6):2001-11.
2012: Adrien Six; Véronique Thomas-Vaslin; Bertrand Bellier; David Klatzmann
Systems biology in vaccine design.
Microbial biotechnology 2012;5(2):295-304.
2012: Hang-Phuong Pham; Adrien Six; Nicolas Petit; Sylvia Cohen-Kaminsky; David Klatzmann; Manuarii Manuel; Gilles Marodon
Half of the T-cell repertoire combinatorial diversity is genetically determined in humans and humanized mice.
European journal of immunology 2012;42(3):760-70.
2012: Serge Herson; Jean-Yves Hogrel; David Klatzmann; Pascal Laforêt; François M Lemoine; France Leturcq; Thierry Maisonobe; Carole Masurier; Marie Montus; Richard C Mulligan; A Rigolet; Norma B Romero; H Lee Sweeney; Thomas Voït; Didier Caizergues; Pierre Carlier; Mustapha Cheraï; Bruno Eymard; Christophe Georger; Bernard Gjata; Hafedh Haddad; Faycal Hentati; Ariane Herson; Yves Allenbach; Rim Amouri; Muriel Audit; Anthony Behin; Olivier Benveniste
A phase I trial of adeno-associated virus serotype 1-γ-sarcoglycan gene therapy for limb girdle muscular dystrophy type 2C.
Brain : a journal of neurology 2012;135(Pt 2):483-92.
2012: Maude Guillot-Delost; Stéphane Kerbrat; David Klatzmann; Sabine Le Gouvello; Claude Baillou; François Berrehar; Nathalie Chaput; Mustapha Cheraï; Yves Levy; Samy Louafi; Mariana Mesel-Lemoine; Anne Simon; Laurence Weiss; François M Lemoine
Human CD90 identifies Th17/Tc17 T cell subsets that are depleted in HIV-infected patients.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(3):981-91.
2012: Hugues Bersini; David Klatzmann; Adrien Six; Véronique Thomas-Vaslin
State-transition diagrams for biologists.
PloS one 2012;7(7):e41165.
2012: Jacek Blazewicz; Marcin Borowski; Wahiba Chaara; Pawel Kedziora; David Klatzmann; Piotr Lukasiak; Adrien Six; Pawel Wojciechowski
GeVaDSs - decision support system for novel Genetic Vaccine development process.
BMC bioinformatics 2012;13():91.
2011: David Saadoun; Damien Sene; Adrien Six; Vincent Thibault; Patrice Cacoub; Fabrice CARRAT; Florence Joly; Michelle Rosenzwajg; David Klatzmann
Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis.
The New England journal of medicine 2011;365(22):2067-77.
2011: Guillaume Darrasse-Jèze; David Klatzmann
[Immunotherapy of cancer: light at the end of the tunnel?].
Médecine sciences : M/S 2011;27(10):795-7.
2011: Guillaume Geri; David Klatzmann; Lucile Musset; Michelle Rosenzwajg; Danielle Seilhean; Vassili Soumelis; Benjamin Terrier; Maxime Touzot; Tu-Anh Tran; Bertrand Wechsler; Bahram Bodaghi; Patrice Cacoub; David Saadoun
Critical role of IL-21 in modulating TH17 and regulatory T cells in Behçet disease.
The Journal of allergy and clinical immunology 2011;128(3):655-64.
2011: Pierre Garrone; Emmanuel Gauthier; David Klatzmann; Dimitri Lavillette; Roger LeGrand; Jimmy Mancip; Isabelle Mangeot; Philippe-Emmanuel Mangeot; Frederic Tangy; Bertrand Bellier; Arnaud Cangialosi; François-Loic Cosset; Isaure Du Chéné; Pia Dupeyrot-Lacas; Anne-Catherine Fluckiger; Charlotte Dalba
A prime-boost strategy using virus-like particles pseudotyped for HCV proteins triggers broadly neutralizing antibodies in macaques.
Science translational medicine 2011;3(94):94ra71.
2011: Lea Torrieri-Dramard; Bénédicte Lambrecht; Helena Ferreira; Thierry Van den Berg; David Klatzmann; Bertrand Bellier
Intranasal DNA vaccination induces potent mucosal and systemic immune responses and cross-protective immunity against influenza viruses.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(3):602-11.
2011: Michelle Rosenzwajg; Nathalie Dhédin; Sébastien Maury; Gilbert Bensimon; Dan-Avi Landau; Françoise Norol; Hélène Trébéden-Negre; Madalina Uzunov; Jean-Paul Vernant; David Klatzmann; José L Cohen
Regulatory T cell content in the bone marrow graft does not predict the occurrence of acute GVHD.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2011;17(2):265-9.
2010: Yenkel Grinberg-Bleyer; David Saadoun; Audrey Baeyens; Fabienne Billiard; Jérémie D Goldstein; Sylvie Grégoire; Gaëlle H Martin; Rima Elhage; Nicolas Derian; Wassila Carpentier; Gilles Marodon; David Klatzmann; Eliane Piaggio; Benoît L Salomon
Pathogenic T cells have a paradoxical protective effect in murine autoimmune diabetes by boosting Tregs.
The Journal of clinical investigation 2010;120(12):4558-68.
2010: Hélène Trébéden-Negre; Michelle Rosenzwajg; Marie-Laure Tanguy; François Lefrere; Nabih Azar; Farhad Heshmati; Ramdane Belhocine; Jean-Paul Vernant; David Klatzmann; Françoise Norol
Delayed recovery after autologous peripheral hematopoietic cell transplantation: potential effect of a high number of total nucleated cells in the graft.
Transfusion 2010;50(12):2649-59.
2010: Benjamin Terrier; Ivan Bièche; Thierry Maisonobe; Ingrid Laurendeau; Michèlle Rosenzwajg; Jean-Emmanuel Kahn; Marie-Claude Diemert; Lucile Musset; Michel Vidaud; Damien Sène; Nathalie Costedoat-Chalumeau; Du Le Thi-Huong; Zahir Amoura; David Klatzmann; Patrice Cacoub; David Saadoun
Interleukin-25: a cytokine linking eosinophils and adaptive immunity in Churg-Strauss syndrome.
Blood 2010;116(22):4523-31.
2010: Yenkel Grinberg-Bleyer; Audrey Baeyens; Sylvaine You; Rima Elhage; Gwladys Fourcade; Sylvie Gregoire; Nicolas Cagnard; Wassila Carpentier; Qizhi Tang; Jeffrey Bluestone; Lucienne Chatenoud; David Klatzmann; Benoît L Salomon; Eliane Piaggio
IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells.
The Journal of experimental medicine 2010;207(9):1871-8.
2010: Sébastien Maury; francois Lemoine; Yosr Hicheri; Michelle Rosenzwajg; Cécile Badoual; Mustapha Cheraï; Jean-Louis Beaumont; Nabih Azar; Nathalie Dhedin; Anne Sirvent; Agnès Buzyn; Marie-Thérèse Rubio; Stéphane Vigouroux; Olivier Montagne; Dominique Bories; Françoise Roudot-Thoraval; Jean-Paul Vernant; Catherine Cordonnier; David Klatzmann; José L Cohen
CD4+CD25+ regulatory T cell depletion improves the graft-versus-tumor effect of donor lymphocytes after allogeneic hematopoietic stem cell transplantation.
Science translational medicine 2010;2(41):41ra52.
2010: Arnaud Suwalski; Hinda Dabboue; Anthony Delalande; Sabine F Bensamoun; Francis Canon; Patrick Midoux; Gérard Saillant; David Klatzmann; Jean-Paul Salvetat; Chantal Pichon
Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles.
Biomaterials 2010;31(19):5237-45.
2010: Helena Ferreira; Bénédicte Lambrecht; Steven Van Borm; Lea Torrieri-Dramard; David Klatzmann; Bertrand Bellier; Thierry van den Berg
Identification of a dominant epitope in the hemagglutinin of an Asian highly pathogenic avian influenza H5N1 clade 1 virus by selection of escape mutants.
Avian diseases 2010;54(1 Suppl):565-71.
2009: Bertrand Bellier; Christophe Huret; Mathilde Miyalou; Delphine Desjardins; Marie-Pascale Frenkiel; Philippe Despres; Fréderic Tangy; Charlotte Dalba; David Klatzmann
DNA vaccines expressing retrovirus-like particles are efficient immunogens to induce neutralizing antibodies.
Vaccine 2009;27(42):5772-80.
2009: Guillaume Darrasse-Jèze; Anne-Sophie Bergot; Aurélie Durgeau; Fabienne Billiard; Benoît L Salomon; José L Cohen; Bertrand Bellier; Katrina Podsypanina; David Klatzmann
Tumor emergence is sensed by self-specific CD44hi memory Tregs that create a dominant tolerogenic environment for tumors in mice.
The Journal of clinical investigation 2009;119(9):2648-62.
2009: francois Lemoine; Mustapha Cherai; Camille Giverne; Dalia Dimitri; Michelle Rosenzwajg; Helene Trebeden-Negre; Nathalie Chaput; Benoit Barrou; Nicolas Thioun; Bernard Gattegnio; Frederic Selles; Alain Six; Nabih Azar; Jean Pierre Lotz; Agnes Buzyn; Mathilde Sibony; Annick Delcourt; Olivier Boyer; Serge Herson; David Klatzmann; Roger Lacave
Massive expansion of regulatory T-cells following interleukin 2 treatment during a phase I-II dendritic cell-based immunotherapy of metastatic renal cancer.
International journal of oncology 2009;35(3):569-81.
2009: Gilles Marodon; Delphine Desjardins; Laetitia Mercey; Claude Baillou; Pierric Parent; Manuarii Manuel; Christophe Caux; Bertrand Bellier; Nicolas Pasqual; David Klatzmann
High diversity of the immune repertoire in humanized NOD.SCID.gamma c-/- mice.
European journal of immunology 2009;39(8):2136-45.
2009: Maude Guillot-Delost; Mustapha Cheraï; Yamina Hamel; Michelle Rosenzwajg; Claude Baillou; G Simonin; Virginie Leclercq; Maria Encarnita Mariotti-Ferrandiz; Adrien Six; Véronique Bon-Durand; Sébastien Maury; Benoît L Salomon; José L Cohen; David Klatzmann; francois Lemoine
Clinical grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene: authors' reponse.
The journal of gene medicine 2009;11(8):737-8.
2009: Delphine Desjardins; Christophe Huret; Charlotte Dalba; Florian Kreppel; Stefan Kochanek; François-Loïc Cosset; Frédéric Tangy; David Klatzmann; Bertrand Bellier
Recombinant retrovirus-like particle forming DNA vaccines in prime-boost immunization and their use for hepatitis C virus vaccine development.
The journal of gene medicine 2009;11(4):313-25.
2009: N Chaput; S Louafi; A Bardier; Frédéric Charlotte; J-C Vaillant; Fabrice Ménégaux; M Rosenzwajg; francois Lemoine; David Klatzmann; J Taieb
Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue.
Gut 2009;58(4):520-9.
2009: Yves Allenbach; Sounkary Solly; sylvie Grégoire; Odile Dubourg; Benoit Salomon; Gillian Butler-Browne; Lucile Musset; Serge Herson; David Klatzmann; Olivier Benveniste
Role of regulatory T cells in a new mouse model of experimental autoimmune myositis.
The American journal of pathology 2009;174(3):989-98.
2009: Aurélie Moreau; Rita Vicente; Laurence Dubreil; Oumeya Adjali; Guillaume Podevin; Chantal Jacquet; Jack-Yves Deschamps; David Klatzmann; Yan Cherel; Naomi Taylor; Philippe Moullier; Valérie S Zimmermann
Efficient intrathymic gene transfer following in situ administration of a rAAV serotype 8 vector in mice and nonhuman primates.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(3):472-9.
2009: D-A Landau; Michelle Rosenzwajg; David Saadoun; David Klatzmann; Patrice Cacoub
The B lymphocyte stimulator receptor-ligand system in hepatitis C virus-induced B cell clonal disorders.
Annals of the rheumatic diseases 2009;68(3):337-44.
2009: Cleonice A M Bento; Joana Hygino; Regis M Andrade; Carmen S M Saramago; Renato G Silva; Agostinho A L Silva; Ulisses C Linhares; Rodrigo Brindeiro; Amilcar Tanuri; Michelle Rosenzwajg; David Klatzmann; Arnaldo F B Andrade
IL-10-secreting T cells from HIV-infected pregnant women downregulate HIV-1 replication: effect enhanced by antiretroviral treatment.
AIDS (London, England) 2009;23(1):9-18.
2008: Béatrice Aussilhou; Yves Panis; Arnaud Alves; Carole Nicco; David Klatzmann
Tumor recurrence after partial hepatectomy for liver metastases in rats: prevention by in vivo injection of irradiated cancer cells expressing GMCSF and IL-12.
The Journal of surgical research 2008;149(2):184-91.
2008: Dan-Avi Landau; Michelle Rosenzwajg; David Saadoun; Hélène Trébeden-Negre; David Klatzmann; Patrice Cacoub
Correlation of clinical and virologic responses to antiviral treatment and regulatory T cell evolution in patients with hepatitis C virus-induced mixed cryoglobulinemia vasculitis.
Arthritis and rheumatism 2008;58(9):2897-907.
2008: Maude Guillot-Delost; Mustapha Cheraï; Yamina Hamel; Michelle Rosenzwajg; Claude Baillou; G Simonin; Virginie Leclercq; Maria Encarnita Mariotti-Ferrandiz; Adrien Six; Véronique Bon-Durand; Sébastien Maury; Benoît L Salomon; José L Cohen; David Klatzmann; francois Lemoine
Clinical-grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene.
The journal of gene medicine 2008;10(8):834-46.
2008: David Saadoun; Michelle Rosenzwajg; Dan Landau; Jean Charles Piette; David Klatzmann; Patrice Cacoub
Restoration of peripheral immune homeostasis after rituximab in mixed cryoglobulinemia vasculitis.
Blood 2008;111(11):5334-41.
2008: Sébastien Maury; Catherine Cordonnier; Mathieu Kuentz; David Klatzmann; José L Cohen
Searching for factors to improve the antileukemic effect of donor lymphocyte infusion.
Blood 2008;111(10):5256; author reply 5256-7.
2008: Véronique Thomas-Vaslin; Hester Korthals Altes; Rob J de Boer; David Klatzmann
Comprehensive assessment and mathematical modeling of T cell population dynamics and homeostasis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2240-50.
2008: Céline Terrada; M Pâques; Sylvain Fisson; Yvonne de Kozak; David Klatzmann; Benoît L Salomon; Phuc LeHoang; Bahram Bodaghi
[Neoretinal antigen expression: a comparison of anatomical and clinical features of a murine uveoretinitis model].
Journal français d'ophtalmologie 2008;31(2):147-54.
2007: Nathalie Chaput; Guillaume Darrasse-Jèze; Anne-Sophie Bergot; Corinne Cordier; Stacie Ngo-Abdalla; David Klatzmann; Orly Azogui
Regulatory T cells prevent CD8 T cell maturation by inhibiting CD4 Th cells at tumor sites.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):4969-78.
2007: Françoise Norol; Nicolas Bonnet; André Peinnequin; fabrice Chretien; Roger Legrand; Richard Isnard; Francis Herodin; Claude Baillou; Benoit Delache; Didier Negre; David Klatzmann; Jean-Paul Vernant; francois Lemoine
GFP-transduced CD34+ and Lin- CD34- hematopoietic stem cells did not adopt a cardiac phenotype in a nonhuman primate model of myocardial infarct.
Experimental hematology 2007;35(4):653-61.
2007: Charlotte Dalba; Bertrand Bellier; Noriyuki Kasahara; David Klatzmann
Replication-competent vectors and empty virus-like particles: new retroviral vector designs for cancer gene therapy or vaccines.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(3):457-66.
2007: Enguerran Mouly; Céline Dorival; Françoise Pflumio; Claude Baillou; Laure Coulombel; Yves Levy; francois Lemoine; David Klatzmann; Gilles Marodon
CD4 regulation in human lymphoid non-T-cells: a role for the silencer element.
Molecular immunology 2007;44(4):267-75.
2006: Gilles Marodon; Sylvain Fisson; Béatrice Levacher; Monique Fabre; Benoît L Salomon; David Klatzmann
Induction of antigen-specific tolerance by intrathymic injection of lentiviral vectors.
Blood 2006;108(9):2972-8.
2006: Carlos Barcia; Clare E Thomas; James F Curtin; Gwendalyn D King; Kolja Wawrowsky; Marianela Candolfi; Wei-Dong Xiong; Chunyan Liu; Kurt M Kroeger; Olivier Boyer; Jerzy W Kupiec-Weglinski; David Klatzmann; Maria G Castro; Pedro R Lowenstein
In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain.
The Journal of experimental medicine 2006;203(9):2095-107.
2006: Fabienne Billiard; Elena Litvinova; David Saadoun; Fathia Djelti; David Klatzmann; José L Cohen; Gilles Marodon; Benoît L Salomon
Regulatory and effector T cell activation levels are prime determinants of in vivo immune regulation.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(4):2167-74.
2006: Muriel Sudres; Françoise Norol; Aurelie Bauquet; sylvie Grégoire; Frédéric Charlotte; Béatrice Levacher; Jean-Jacques Lataillade; philippe Bourin; Xavier Holy; Jean-Paul Vernant; David Klatzmann; José L Cohen
Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7761-7.
2006: Céline Terrada; Sylvain Fisson; Yvonne de Kozak; Mohammed Kaddouri; Phuc LeHoang; David Klatzmann; Benoît L Salomon; Bahram Bodaghi
Regulatory T cells control uveoretinitis induced by pathogenic Th1 cells reacting to a specific retinal neoantigen.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7171-9.
2006: Sylvain Fisson; Fathia Djelti; Aurelie Bauquet; Fabienne Billiard; Roland S Liblau; David Klatzmann; José L Cohen; Benoît L Salomon
Therapeutic potential of self-antigen-specific CD4+ CD25+ regulatory T cells selected in vitro from a polyclonal repertoire.
European journal of immunology 2006;36(4):817-27.
2006: Dalia Dimitri; Olivier Benveniste; Odile Dubourg; Thierry Maisonobe; Bruno Eymard; Zahir Amoura; Laetitia Jean; Kiet Phong TIEV; Jean-Charles Piette; David Klatzmann; Serge Herson; Olivier Boyer
Shared blood and muscle CD8+ T-cell expansions in inclusion body myositis.
Brain : a journal of neurology 2006;129(Pt 4):986-95.
2006: Bertrand Bellier; Charlotte Dalba; Béatrice Clerc; Delphine Desjardins; Rosybel Drury; François-Loïc Cosset; Mary Collins; David Klatzmann
DNA vaccines encoding retrovirus-based virus-like particles induce efficient immune responses without adjuvant.
Vaccine 2006;24(14):2643-55.
2006: Hafid Ait-Oufella; Benoît L Salomon; Stephane Potteaux; Anna-Karin L Robertson; Pierre Gourdy; Joffrey Zoll; Régine Merval; Bruno Esposito; José L Cohen; Sylvain Fisson; Richard A Flavell; Göran K Hansson; David Klatzmann; Alain Tedgui; Ziad Mallat
Natural regulatory T cells control the development of atherosclerosis in mice.
Nature medicine 2006;12(2):178-80.
2006: Julien Taieb; Nathalie Chaput; Cédric Ménard; Lionel Apetoh; Evelyn Ullrich; Mathieu Bonmort; Marie Péquignot; Noelia Casares; Magali Terme; Caroline Flament; Paule Opolon; Yann Lecluse; Didier Métivier; Elena Tomasello; Eric Vivier; François Ghiringhelli; François Martin; David Klatzmann; Thierry Poynard; Thomas Tursz; Graça Raposo; Hideo Yagita; Bernard Ryffel; Guido Kroemer; Laurence Zitvogel
A novel dendritic cell subset involved in tumor immunosurveillance.
Nature medicine 2006;12(2):214-9.
2006: Jamila Khallou-Laschet; giuseppina caligiuri; Emilie Groyer; Emmanuel Tupin; Anh-Thu Gaston; Bruno Poirier; Mitchell Kronenberg; José L Cohen; David Klatzmann; Srini V Kaveri; Antonino Nicoletti
The proatherogenic role of T cells requires cell division and is dependent on the stage of the disease.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(2):353-8.
2006: Aurelie Bauquet; Muriel Sudres; Qizhi Tang; Sébastien Maury; Frédéric Charlotte; sylvie Grégoire; Mark Bonyhadi; David Klatzmann; Benoît L Salomon; José L Cohen
Ex vivo-expanded CD4+CD25+ immunoregulatory T cells prevent graft-versus-host-disease by inhibiting activation/differentiation of pathogenic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(2):1266-73.
2006: Guillaume Darrasse-Jèze; Guillaume Darasse-Jèze; David Klatzmann; Frédéric Charlotte; Benoît L Salomon; José L Cohen
CD4+CD25+ regulatory/suppressor T cells prevent allogeneic fetus rejection in mice.
Immunology letters 2006;102(1):106-9.
2006: Judit Szécsi; Bertrand Boson; Per Johnsson; Pia Dupeyrot-Lacas; Mikhail Matrosovich; Hans-Dieter Klenk; David Klatzmann; Viktor Volchkov; François-Loïc Cosset
Induction of neutralising antibodies by virus-like particles harbouring surface proteins from highly pathogenic H5N1 and H7N1 influenza viruses.
Virology journal 2006;3():70.
2006: Weijun Wang; Chien-Kuo Tai; Allan D Kershaw; Sounkary K Solly; David Klatzmann; Noriyuki Kasahara; Thomas C Chen
Use of replication-competent retroviral vectors in an immunocompetent intracranial glioma model.
Neurosurgical focus 2006;20(4):E25.
2006: Mariana Mesel-Lemoine; Mustapha Cherai; Sabine Le Gouvello; Maude Guillot; Virginie Leclercq; David Klatzmann; Véronique Thomas-Vaslin; francois Lemoine
Initial depletion of regulatory T cells: the missing solution to preserve the immune functions of T lymphocytes designed for cell therapy.
Blood 2006;107(1):381-8.
2005: Charlotte Dalba; David Klatzmann; Christopher R Logg; Noriyuki Kasahara
Beyond oncolytic virotherapy: replication-competent retrovirus vectors for selective and stable transduction of tumors.
Current gene therapy 2005;5(6):655-67.
2005: Franck P Dupuy; Enguerran Mouly; Mariana Mesel-Lemoine; Céline Morel; Julien Abriol; Mustapha Cherai; Claude Baillou; Didier Nègre; François-Loïc Cosset; David Klatzmann; francois Lemoine
Lentiviral transduction of human hematopoietic cells by HIV-1- and SIV-based vectors containing a bicistronic cassette driven by various internal promoters.
The journal of gene medicine 2005;7(9):1158-71.
2005: Oumeya Adjali; Gilles Marodon; Marcos Steinberg; Cédric Mongellaz; Véronique Thomas-Vaslin; Chantal Jacquet; Naomi Taylor; David Klatzmann
In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer.
The Journal of clinical investigation 2005;115(8):2287-95.
2005: Guillaume Darrasse-Jèze; Gilles Marodon; Benoît L Salomon; Martin Catala; David Klatzmann
Ontogeny of CD4+CD25+ regulatory/suppressor T cells in human fetuses.
Blood 2005;105(12):4715-21.
2005: Birgitta M Wöhrl; Laurence Loubière; Ralf Brundiers; Roger S Goody; David Klatzmann; Manfred Konrad
Expressing engineered thymidylate kinase variants in human cells to improve AZT phosphorylation and human immunodeficiency virus inhibition.
The Journal of general virology 2005;86(Pt 3):757-64.
2005: Stéphane Trajcevski; Sounkary K Solly; Charlotte Frisén; Aurelie Bauquet; François-Loïc Cosset; David Klatzmann
Characterization of a semi-replicative gene delivery system allowing propagation of complementary defective retroviral vectors.
The journal of gene medicine 2005;7(3):276-87.
2005: Kiet Phong TIEV; Julien Abriol; MC Burland; D Antonelli; David Klatzmann; jean paul cabane; Olivier Boyer
T cell repertoire in patients with stable scleroderma.
Clinical and experimental immunology 2005;139(2):348-54.
2004: David Saadoun; Olivier Boyer; Hélène Trébeden-Nègre; Nicolas Limal; Véronique Bon-Durand; Marita Andreu; David Klatzmann; Jean Charles Piette; Patrice Cacoub
Predominance of type 1 (Th1) cytokine production in the liver of patients with HCV-associated mixed cryoglobulinemia vasculitis.
Journal of hepatology 2004;41(6):1031-7.
2004: Olivier Benveniste; Serge Herson; Benoît L Salomon; Dalia Dimitri; Hélène Trébeden-Nègre; Laetitia Jean; Véronique Bon-Durand; David Antonelli; David Klatzmann; Olivier Boyer
Long-term persistence of clonally expanded T cells in patients with polymyositis.
Annals of neurology 2004;56(6):867-72.
2004: Arnaud Alves; Eric Vibert; Stéphane Trajcevski; Sounkary K Solly; Monique Fabre; Olivier Soubrane; Cheng Qian; Jesus Prieto; David Klatzmann; Yves Panis
Adjuvant interleukin-12 gene therapy for the management of colorectal liver metastases.
Cancer gene therapy 2004;11(12):782-9.
2004: Norma B Romero; Serge Braun; Olivier Benveniste; France Leturcq; Jean-Yves Hogrel; Glenn E Morris; Annie Barois; Bruno Eymard; Christine Payan; Véronique Ortega; Anne-Laure Boch; Lise Lejean; Christine Thioudellet; Brigitte Mourot; Christophe Escot; Aurore Choquel; Dominique Recan; Jean-Claude Kaplan; George Dickson; David Klatzmann; Valérie Molinier-Frenckel; Jean-Gérard Guillet; Patrick Squiban; Serge Herson; Michel Fardeau
Phase I study of dystrophin plasmid-based gene therapy in Duchenne/Becker muscular dystrophy.
Human gene therapy 2004;15(11):1065-76.
2004: Gilles Marodon; David Klatzmann
In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors.
BMC immunology 2004;5():18.
2004: Béatrice Clémenceau; Géraldine Gallot; francois Lemoine; David Klatzmann; Henri Vié
Preparation of genetically homogeneous antigen-specific thymidine kinase positive T-lymphocyte clones for the control of alloreactivity post-bone marrow transplantation.
Human gene therapy 2004;15(6):542-52.
2004: Fatima Serhan; Magalie Penaud; Caroline Petit; Thierry Leste-Lasserre; Stéphane Trajcevski; David Klatzmann; Ghislaine Duisit; Pierre Sonigo; Philippe Moullier
Early detection of a two-long-terminal-repeat junction molecule in the cytoplasm of recombinant murine leukemia virus-infected cells.
Journal of virology 2004;78(12):6190-9.
2004: Olivier Boyer; David Saadoun; Julien Abriol; Mélanie Dodille; Jean-Charles Piette; Patrice Cacoub; David Klatzmann
CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis.
Blood 2004;103(9):3428-30.
2004: francois Lemoine; Mariana Mesel-Lemoine; Mustapha Cherai; Géraldine Gallot; Henri Vié; Virginie Leclercq; Hélène Trébèden-Negre; Olivier Mammès; Olivier Boyer; Patricia Noguiez-Hellin; David Klatzmann
Efficient transduction and selection of human T-lymphocytes with bicistronic Thy1/HSV1-TK retroviral vector produced by a human packaging cell line.
The journal of gene medicine 2004;6(4):374-86.
2004: Aurelie Bauquet; Sylvain Fisson; Eric Braunberger; David Klatzmann; Benoît L Salomon; José L Cohen
Ex vivo selection of recipient-type alloantigen-specific CD4(+)CD25(+) immunoregulatory T cells for the control of graft-versus-host disease after allogeneic hematopoietic stem-cell transplantation.
Transplantation 2004;77(1 Suppl):S32-4.
2003: Bertrand Bellier; Véronique Thomas-Vaslin; Marie-Françoise Saron; David Klatzmann
Turning immunological memory into amnesia by depletion of dividing T cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15017-22.
2003: Aurelie Bauquet; Frédéric Charlotte; Sylvain Fisson; Micael Yagello; David Klatzmann; Benoît L Salomon; José L Cohen
Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia.
The Journal of clinical investigation 2003;112(11):1688-96.
2003: Roger Lacave; Carole Masurier; Martine Guigon; francois Lemoine; David Klatzmann; Bruno M Colombo
Similar immune responses and antitumor effects of murine dendritic cells loaded with either exogenous or endogenous-synthesized protein.
International journal of oncology 2003;23(6):1747-53.
2003: Sylvain Fisson; Guillaume Darrasse-Jèze; Elena Litvinova; Franck Septier; David Klatzmann; Roland S Liblau; Benoît L Salomon
Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.
The Journal of experimental medicine 2003;198(5):737-46.
2003: Marc Jayankura; Christophe Boggione; Charlotte Frisén; Olivier Boyer; Pierre Fouret; Gérard Saillant; David Klatzmann
In situ gene transfer into animal tendons by injection of naked DNA and electrotransfer.
The journal of gene medicine 2003;5(7):618-24.
2003: Arnaud Alves; Lionel Charre; Yves Panis; Jorge Cardoso; Monique Fabre; Edith Brisson; Didier Houssin; Olivier Soubrane; David Klatzmann
Total vascular exclusion of the liver enhances the efficacy of retroviral-mediated associated thymidine kinase and interleukin-2 genes transfer against multiple hepatic tumors in rats.
Surgery 2003;133(6):669-77.
2003: Gilles Marodon; Enguerran Mouly; Emma J Blair; Charlotte Frisen; francois Lemoine; David Klatzmann
Specific transgene expression in human and mouse CD4+ cells using lentiviral vectors with regulatory sequences from the CD4 gene.
Blood 2003;101(9):3416-23.
2003: Claude Baillou; Anne Simon; Virginie Leclercq; Nabih Azar; Michelle Rosenzwajg; Serge Herson; David Klatzmann; francois Lemoine
Highly active antiretroviral therapy corrects hematopoiesis in HIV-1 infected patients: interest for peripheral blood stem cell-based gene therapy.
AIDS (London, England) 2003;17(4):563-74.
2003: Sounkary K Solly; Stéphane Trajcevski; Charlotte Frisén; Georg W Holzer; Elisabeth Nelson; Béatrice Clerc; Evelyn Abordo-Adesida; Maria Castro; Pedro Lowenstein; David Klatzmann
Replicative retroviral vectors for cancer gene therapy.
Cancer gene therapy 2003;10(1):30-9.
2002: Xing Fan; Yan Aalto; Stephen G Sanko; Sakari Knuutila; David Klatzmann; Javier S Castresana
Genetic profile, PTEN mutation and therapeutic role of PTEN in glioblastomas.
International journal of oncology 2002;21(5):1141-50.
2002: Olivier Boyer; Gilles Marodon; José L Cohen; Laurence Lejeune; Theano Irinopoulou; Roland S Liblau; Patrick Bruneval; David Klatzmann
Human CD4 expression at the late single-positive stage of thymic development supports T cell maturation and peripheral export in CD4-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4347-53.
2002: Elena Litvinova; Sébastien Maury; Olivier Boyer; Sylvie Bruel; Laurent Benard; Gilbert Boisserie; David Klatzmann; José L Cohen
Graft-versus-leukemia effect after suicide-gene-mediated control of graft-versus-host disease.
Blood 2002;100(6):2020-5.
2002: José L Cohen; Aurelie Bauquet; Douglas Vasey; David Klatzmann; Benoît L Salomon
CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease.
The Journal of experimental medicine 2002;196(3):401-6.
2002: Carsten Engelmann; Jean-Marie Heslan; Monique Fabre; Jean Pierre Lagarde; David Klatzmann; Yves Panis
Importance, mechanisms and limitations of the distant bystander effect in cancer gene therapy of experimental liver tumors.
Cancer letters 2002;179(1):59-69.
2002: Charles A Valéry; Danielle Seilhean; Olivier Boyer; Béatrice Marro; JEAN-JACQUES HAUW; J-L Kemeny; Claude Marsault; Jacques Philippon; David Klatzmann
Long-term survival after gene therapy for a recurrent glioblastoma.
Neurology 2002;58(7):1109-12.
2002: Sébastien Maury; Elena Litvinova; Olivier Boyer; L Benard; Sylvie Bruel; David Klatzmann; José L Cohen
Effect of combined cytostatic cyclosporin A and cytolytic suicide gene therapy on the prevention of experimental graft-versus-host disease.
Gene therapy 2002;9(3):201-7.
2001: S Maury; Benoît L Salomon; David Klatzmann; José L Cohen
Division rate and phenotypic differences discriminate alloreactive and nonalloreactive T cells transferred in lethally irradiated mice.
Blood 2001;98(10):3156-8.
2001: José L Cohen; Olivier Boyer; David Klatzmann
Suicide gene therapy of graft-versus-host disease: immune reconstitution with transplanted mature T cells.
Blood 2001;98(7):2071-6.
2001: Olivier Benveniste; Patrick Chérin; Thierry Maisonobe; R Merat; O Chosidow; Luc Mouthon; L Guillevin; Antoine Flahault; MC Burland; David Klatzmann; Serge Herson; Olivier Boyer
Severe perturbations of the blood T cell repertoire in polymyositis, but not dermatomyositis patients.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(6):3521-9.
2001: Charles A Valéry; Béatrice Marro; Olivier Boyer; Michel Duyme; Karima Mokhtari; Claude Marsault; David Klatzmann; Jacques Philippon
Extent of tumor-brain interface: a new tool to predict evolution of malignant gliomas.
Journal of neurosurgery 2001;94(3):433-6.
2000: José L Cohen; Marie-Françoise Saron; Olivier Boyer; Véronique Thomas-Vaslin; Bertrand Bellier; Laurence Lejeune; Frédéric Charlotte; David Klatzmann
Preservation of graft-versus-infection effects after suicide gene therapy for prevention of graft-versus-host disease.
Human gene therapy 2000;11(18):2473-81.
2000: Eric Braunberger; José L Cohen; Olivier Boyer; Beatrice Pegaz-Fiornet; N Raynal-Raschilas; P Bruneval; Véronique Thomas-Vaslin; Bertrand Bellier; Alain Carpentier; Denis Glotz; David Klatzmann
T-Cell suicide gene therapy for organ transplantation: induction of long-lasting tolerance to allogeneic heart without generalized immunosuppression.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(6):596-601.
2000: HJ Nagy; Yves Panis; Monique Fabre; David Klatzmann; Didier Houssin; Olivier Soubrane
Suicide gene therapy of ovarian cancer: an experimental study in rats using retroviral-mediated transfer of herpes simplex virus thymidine kinase gene.
Anticancer research 2000;20(6B):4633-8.
2000: JC Zhao-Emonet; Gilles Marodon; C Pioche-Durieu; François-Loïc Cosset; David Klatzmann
T cell-specific expression from Mo-MLV retroviral vectors containing a CD4 mini-promoter/enhancer.
The journal of gene medicine 2000;2(6):416-25.
2000: HJ Nagy; Yves Panis; Monique Fabre; C Engelmann; Olivier Soubrane; Didier Houssin; David Klatzmann
Efficient suicide gene therapy of transduced and distant untransduced ovary tumors is correlated with significant increase of intratumoral T and NK cells.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2000;54(10):479-86.
2000: Olivier Boyer; José L Cohen; Bertrand Bellier; Véronique Thomas-Vaslin; David Klatzmann; Marie-Françoise Saron
Transient control of a virus-induced immunopathology by genetic immunosuppression.
Gene therapy 2000;7(18):1536-42.
2000: C Torrent; C Jullien; David Klatzmann; Michel Perricaudet; Patrice Yeh
Transgene amplification and persistence after delivery of retroviral vector and packaging functions with E1/E4-deleted adenoviruses.
Cancer gene therapy 2000;7(8):1135-44.
2000: Véronique Thomas-Vaslin; Bertrand Bellier; José L Cohen; Olivier Boyer; N Raynal-Raschilas; Denis Glotz; David Klatzmann
Prolonged allograft survival through conditional and specific ablation of alloreactive T cells expressing a suicide gene.
Transplantation 2000;69(10):2154-61.
2000: M Movassagh; Olivier Boyer; MC Burland; Virginie Leclercq; David Klatzmann; francois Lemoine
Retrovirus-mediated gene transfer into T cells: 95% transduction efficiency without further in vitro selection.
Human gene therapy 2000;11(8):1189-200.
2000: S Oudin; MT Libyh; D Goossens; Xavier Dervillez; Frédérique Philbert; Brigitte Réveil; F Bougy; Thierry Tabary; Philippe Rouger; David Klatzmann; Jacques H M Cohen
A soluble recombinant multimeric anti-Rh(D) single-chain Fv/CR1 molecule restores the immune complex binding ability of CR1-deficient erythrocytes.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1505-13.
2000: Bruno M Colombo; Roger Lacave; C Pioche-Durieu; Carole Masurier; francois Lemoine; Martine Guigon; David Klatzmann
Cellular but not humoral immune responses generated by vaccination with dendritic cells protect mice against leukaemia.
Immunology 2000;99(1):8-15.
2000: Eric Braunberger; N Raynal-Raschilas; Véronique Thomas-Vaslin; P Bruneval; Jean-Noël Fabiani; Alain Carpentier; Denis Glotz; David Klatzmann
Tolerance induced without immunosuppression in a T-lymphocyte suicide-gene therapy cardiac allograft model in mice.
The Journal of thoracic and cardiovascular surgery 2000;119(1):46-51.
1999: Eiji SHINYA; Xavier Dervillez; Florence Edwards; V Duret; Edith Brisson; Loyda Ylisastigui; Marie-Christine Lévy; Jacques H M Cohen; David Klatzmann
In-vivo delivery of therapeutic proteins by genetically-modified cells: comparison of organoids and human serum albumin alginate-coated beads.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1999;53(10):471-83.
1999: José L Cohen; Sébastien Lacroix-Desmazes; Frédéric Charlotte; Laurence Lejeune; P J Martin; David Klatzmann; Olivier Boyer
Immunological defects after suicide gene therapy of experimental graft-versus-host disease.
Human gene therapy 1999;10(16):2701-7.
1999: Laurence Loubière; M Tiraby; Christophe Cazaux; Edith Brisson; M Grisoni; JC Zhao-Emonet; Gérard Tiraby; David Klatzmann
The equine herpes virus 4 thymidine kinase is a better suicide gene than the human herpes virus 1 thymidine kinase.
Gene therapy 1999;6(9):1638-42.
1999: José L Cohen; Olivier Boyer; Véronique Thomas-Vaslin; David Klatzmann
Suicide gene-mediated modulation of graft-versus-host disease.
Leukemia & lymphoma 1999;34(5-6):473-80.
1999: C Engelmann; Yves Panis; J Bolard; B Diquet; Monique Fabre; HJ Nagy; Olivier Soubrane; Didier Houssin; David Klatzmann
Liposomal encapsulation of ganciclovir enhances the efficacy of herpes simplex virus type 1 thymidine kinase suicide gene therapy against hepatic tumors in rats.
Human gene therapy 1999;10(9):1545-51.
1999: Carole Masurier; C Pioche-Durieu; Bruno M Colombo; Roger Lacave; francois Lemoine; David Klatzmann; Martine Guigon
Immunophenotypical and functional heterogeneity of dendritic cells generated from murine bone marrow cultured with different cytokine combinations: implications for anti-tumoral cell therapy.
Immunology 1999;96(4):569-77.
1999: M Movassagh; Claude Baillou; François-Loïc Cosset; David Klatzmann; Martine Guigon; francois Lemoine
High level of retrovirus-mediated gene transfer into dendritic cells derived from cord blood and mobilized peripheral blood CD34+ cells.
Human gene therapy 1999;10(2):175-87.
1998: David Klatzmann; Charles A Valéry; Gilbert Bensimon; Béatrice Marro; Olivier Boyer; Karima Mokhtari; B Diquet; J L Salzmann; Jacques Philippon
A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma.
Human gene therapy 1998;9(17):2595-604.
1998: David Klatzmann; Patrick Chérin; Gilbert Bensimon; Olivier Boyer; A Coutellier; Frédéric Charlotte; C Boccaccio; J L Salzmann; Serge Herson
A phase I/II dose-escalation study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for metastatic melanoma. Study Group on Gene Therapy of Metastatic Melanoma.
Human gene therapy 1998;9(17):2585-94.
1998: JC Zhao-Emonet; Olivier Boyer; J L Cohen; David Klatzmann
Deletional and mutational analyses of the human CD4 gene promoter: characterization of a minimal tissue-specific promoter.
Biochimica et biophysica acta 1998;1442(2-3):109-19.
1998: Carole Masurier; Benoît L Salomon; N Guettari; C Pioche; François Lachapelle; Martine Guigon; David Klatzmann
Dendritic cells route human immunodeficiency virus to lymph nodes after vaginal or intravenous administration to mice.
Journal of virology 1998;72(10):7822-9.
1998: José L Cohen; Olivier Boyer; Benoît L Salomon; R Onclerco; D Depetris; Laurence Lejeune; V Dubus-Bonnet; Sylvie Bruel; Frédéric Charlotte; M G Mattéï; David Klatzmann
Fertile homozygous transgenic mice expressing a functional truncated herpes simplex thymidine kinase delta TK gene.
Transgenic research 1998;7(5):321-30.
1998: M X Wei; Philippe Bougnoux; B Sacré-Salem; M B Peyrat; Claude Lhuillery; Jean Loup Salzmann; David Klatzmann
Suicide gene therapy of chemically induced mammary tumor in rat: efficacy and distant bystander effect.
Cancer research 1998;58(16):3529-32.
1998: Christophe Cazaux; M Tiraby; L Loubiere; L Haren; David Klatzmann; Gérard Tiraby
Phosphorylation and cytotoxicity of therapeutic nucleoside analogues: a comparison of alpha and gamma herpesvirus thymidine kinase suicide genes.
Cancer gene therapy 1998;5(2):83-91.
1998: M Movassagh; C Desmyter; Claude Baillou; S Chapel-Fernandes; Martine Guigon; David Klatzmann; francois Lemoine
High-level gene transfer to cord blood progenitors using gibbon ape leukemia virus pseudotype retroviral vectors and an improved clinically applicable protocol.
Human gene therapy 1998;9(2):225-34.
1998: Benoît L Salomon; José L Cohen; Carole Masurier; David Klatzmann
Three populations of mouse lymph node dendritic cells with different origins and dynamics.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):708-17.
1998: HJ Nagy; Yves Panis; Monique Fabre; H Perrin; David Klatzmann; Didier Houssin
Are hepatomas a good target for suicide gene therapy? An experimental study in rats using retroviral-mediated transfer of thymidine kinase gene.
Surgery 1998;123(1):19-24.
1997: MT Libyh; D Goossens; S Oudin; N Gupta; Xavier Dervillez; Geneviève Juszczak; P Cornillet; F Bougy; Brigitte Reveil; Frédérique Philbert; Thierry Tabary; David Klatzmann; Philippe Rouger; Jacques H M Cohen
A recombinant human scFv anti-Rh(D) antibody with multiple valences using a C-terminal fragment of C4-binding protein.
Blood 1997;90(10):3978-83.
1997: A R Kianmanesh; H Perrin; Yves Panis; Monique Fabre; HJ Nagy; Didier Houssin; David Klatzmann
A "distant" bystander effect of suicide gene therapy: regression of nontransduced tumors together with a distant transduced tumor.
Human gene therapy 1997;8(15):1807-14.
1997: Olivier Boyer; J C Zhao; José L Cohen; D Depetris; Micael Yagello; Laurence Lejeune; Sylvie Bruel; M G Mattéï; David Klatzmann
Position-dependent variegation of a CD4 minigene with targeted expression to mature CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3383-90.
1997: V A Morozov; Patricia Noguiez-Hellin; S Laune; E Tamboise; Jean Loup Salzmann; David Klatzmann
Plasmovirus: replication cycle of a novel nonviral/viral vector for gene transfer.
Cancer gene therapy 1997;4(5):286-93.
1997: N Guettari; Laurence Loubière; Edith Brisson; David Klatzmann
Use of herpes simplex virus thymidine kinase to improve the antiviral activity of zidovudine.
Virology 1997;235(2):398-405.
1997: José L Cohen; Olivier Boyer; Benoît L Salomon; R Onclercq; Frédéric Charlotte; Sylvie Bruel; Gilbert Boisserie; David Klatzmann
Prevention of graft-versus-host disease in mice using a suicide gene expressed in T lymphocytes.
Blood 1997;89(12):4636-45.
1997: Benoît L Salomon; Pieter J M Leenen; David Klatzmann
Immune response in dendritic cell depleted mice.
Advances in experimental medicine and biology 1997;417():547-50.
1997: Carole Masurier; N Guettari; C Pioche; Roger Lacave; Benoît L Salomon; François Lachapelle; David Klatzmann; Martine Guigon
The role of dendritic cells in the transport of HIV to lymph nodes analysed in mouse.
Advances in experimental medicine and biology 1997;417():411-4.
1996: P Noguiez-Hellin; M R Meur; Jean Loup Salzmann; David Klatzmann
Plasmoviruses: nonviral/viral vectors for gene therapy.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4175-80.
1996: Y Panis; A R Rad; Olivier Boyer; D Houssin; J L Salzmann; David Klatzmann
Gene therapy for liver tumors.
Surgical oncology clinics of North America 1996;5(2):461-73.
1996: P Salmon; O Boyer; Patrick Lores; Jacques Jami; David Klatzmann
Characterization of an intronless CD4 minigene expressed in mature CD4 and CD8 T cells, but not expressed in immature thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(5):1873-9.
1996: David Klatzmann
Gene therapy for metastatic malignant melanoma: evaluation of tolerance to intratumoral injection of cells producing recombinant retroviruses carrying the herpes simplex virus type 1 thymidine kinase gene, to be followed by ganciclovir administration.
Human gene therapy 1996;7(2):255-67.
1996: N Guettari; L Loubière; M Caruso; David Klatzmann
Genetic pharmacomodulation of nucleoside analogues and gene therapy for AIDS and cancer.
Antibiotics and chemotherapy 1996;48():198-204.
1996: P Noguiez-Hellin; M Robert-Le Meur; S Laune; Jean Loup Salzmann; David Klatzmann
[Generation of a trans-complementable defective recombinant provirus and loading a transgene].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1996;319(1):45-50.
1995: C Pioche; Benoît L Salomon; David Klatzmann
[Dendritic cells and tumor cell therapy].
Pathologie-biologie 1995;43(10):904-9.
1995: Benoît L Salomon; S Maury; L Loubière; M Caruso; R Onclercq; David Klatzmann
A truncated herpes simplex virus thymidine kinase phosphorylates thymidine and nucleoside analogs and does not cause sterility in transgenic mice.
Molecular and cellular biology 1995;15(10):5322-8.
1995: M Caruso; Benoît L Salomon; S Zhang; Edith Brisson; F Clavel; I Lowy; David Klatzmann
Expression of a Tat-inducible herpes simplex virus-thymidine kinase gene protects acyclovir-treated CD4 cells from HIV-1 spread by conditional suicide and inhibition of reverse transcription.
Virology 1995;206(1):495-503.
1995: Benoît L Salomon; C Pioche; Patrick Lores; Jacques Jami; P Racz; David Klatzmann
Conditional ablation of dendritic cells in mice: comparison of two animal models.
Advances in experimental medicine and biology 1995;378():485-7.
1994: M Caruso; David Klatzmann
[Genetically controlled pharmacomodulation: application to the treatment of HIV infection].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1994;317(11):1027-30.
1994: I Lowy; M Caruso; Stephen P Goff; David Klatzmann
Cellular thymidine kinase activity is required for the inhibition of HIV-1 replication by AZT in lymphocytes.
Virology 1994;200(1):271-5.
1994: Benoît L Salomon; Patrick Lores; C Pioche; P Racz; Jacques Jami; David Klatzmann
Conditional ablation of dendritic cells in transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):537-48.
1993: P Salmon; A Giovane; Bohdan Wasylyk; David Klatzmann
Characterization of the human CD4 gene promoter: transcription from the CD4 gene core promoter is tissue-specific and is activated by Ets proteins.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(16):7739-43.
1993: M Caruso; Y Panis; S Gagandeep; D Houssin; J L Salzmann; David Klatzmann
Regression of established macroscopic liver metastases after in situ transduction of a suicide gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7024-8.
1992: M Caruso; G Tsikas; M Roussel; M Alizon; David Klatzmann
Can diphtheria toxin be used for gene therapy of human immunodeficiency virus infection?
AIDS research and human retroviruses 1992;8(12):1949-50.
1992: VIDA CHAMS; T Idziorek; P J Maddon; David Klatzmann
Simple assay to screen for inhibitors of interaction between the human immunodeficiency virus envelope glycoprotein and its cellular receptor, CD4.
Antimicrobial agents and chemotherapy 1992;36(2):267-72.
1992: T Idziorek; VIDA CHAMS; David Klatzmann
Characterization and anti-HIV properties of CD 4-coated red blood cells.
Archives of virology 1992;126(1-4):81-91.
1992: M Caruso; G Tzikas; M Roussel; M Alizon; David Klatzmann
HIV-triggered killing of booby trapped cells prevents viral spread in an HIV-infected cell population.
Bone marrow transplantation 1992;9 Suppl 1():187-8.
1992: M Caruso; David Klatzmann
Selective killing of CD4+ cells harboring a human immunodeficiency virus-inducible suicide gene prevents viral spread in an infected cell population.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):182-6.
1992: Y Panis; M Caruso; D Houssin; M Andreoletti; David Khayat; J L Salzmann; David Klatzmann
[Treatment of experimental liver tumors by in vivo suicide gene transfer in rats].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1992;315(13):541-4.
1991: J S McDougal; David Klatzmann; P J Maddon
CD4-gp120 interactions.
Current opinion in immunology 1991;3(4):552-8.
1991: T Idziorek; David Klatzmann
Construction of CD4-based chimeric molecules by chemical cross-linking.
AIDS research and human retroviruses 1991;7(6):529-36.
1991: VIDA CHAMS; T Idziorek; David Klatzmann
Biological properties of anti-CD4 autoantibodies purified from HIV-infected patients.
AIDS (London, England) 1991;5(5):565-9.
1991: T Idziorek; David Klatzmann
Functional expression of the CD4 protein after cross-linking to red blood cells with a bifunctional reagent.
Biochimica et biophysica acta 1991;1062(1):39-45.
1990: David Klatzmann; J S McDougal; P J Maddon
The CD4 molecule and HIV infection.
Immunodeficiency reviews 1990;2(1):43-66.
1988: VIDA CHAMS; T Jouault; Emmanuel Fenouillet; Jean Claude Gluckman; David Klatzmann
Detection of anti-CD4 autoantibodies in the sera of HIV-infected patients using recombinant soluble CD4 molecules.
AIDS (London, England) 1988;2(5):353-61.