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Jörg Kleeff

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Abiatari Ivane; Gillen Sonja; DeOliveira Tiago; Klose Theresa; Bo Kong; Giese Nathalia A; Friess Helmut; Kleeff Jörg
The microtubule-associated protein MAPRE2 is involved in perineural invasion of pancreatic cancer cells.
Pan Zheng; Erkan Mert; Streit Sylvia; Friess Helmut; Kleeff Jörg
Silencing of GRP94 expression promotes apoptosis in pancreatic cancer cells.
Loftås Per; Onnesjö Sofia; Widegren Emma; Adell Gunnar; Kayed Hany; Kleeff Jörg; Zentgraf Hanswalter; Sun Xiao-Feng
Expression of FXYD-3 is an independent prognostic factor in rectal cancer patients with preoperative radiotherapy.

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All Publications

2009: Abiatari Ivane; Gillen Sonja; DeOliveira Tiago; Klose Theresa; Bo Kong; Giese Nathalia A; Friess Helmut; Kleeff Jörg
The microtubule-associated protein MAPRE2 is involved in perineural invasion of pancreatic cancer cells.
International journal of oncology 2009;35(5):1111-6.
2009: Pan Zheng; Erkan Mert; Streit Sylvia; Friess Helmut; Kleeff Jörg
Silencing of GRP94 expression promotes apoptosis in pancreatic cancer cells.
International journal of oncology 2009;35(4):823-8.
2009: Loftås Per; Onnesjö Sofia; Widegren Emma; Adell Gunnar; Kayed Hany; Kleeff Jörg; Zentgraf Hanswalter; Sun Xiao-Feng
Expression of FXYD-3 is an independent prognostic factor in rectal cancer patients with preoperative radiotherapy.
International journal of radiation oncology, biology, physics 2009;75(1):137-42.
2009: Kolb Armin; Rieder Simon; Born Diana; Giese Nathalia A; Giese Thomas; Rudofsky Gottfried; Werner Jens; Büchler Markus W; Friess Helmut; Esposito Irene; Jörg Kleeff
Glucagon/insulin ratio as a potential biomarker for pancreatic cancer in patients with new-onset diabetes mellitus.
Cancer biology & therapy 2009;8(16):1527-33.
2009: Hüser N; Michalski C W; Schuster T; Friess H; Kleeff J
Systematic review and meta-analysis of prophylactic gastroenterostomy for unresectable advanced pancreatic cancer.
The British journal of surgery 2009;96(7):711-9.
2009: Gillen Sonja; Friess Helmut; Kleeff Jörg
Palliative cardia resection with gastroesophageal reconstruction for perforated carcinoma of the gastroesophageal junction.
World journal of gastroenterology : WJG 2009;15(24):3065-7.
2009: Abiatari Ivane; DeOliveira Tiago; Kerkadze Vachtang; Schwager Christian; Esposito Irene; Giese Nathalia A; Huber Peter; Bergman Frank; Abdollahi Amir; Friess Helmut; Kleeff Jörg
Consensus transcriptome signature of perineural invasion in pancreatic carcinoma.
Molecular cancer therapeutics 2009;8(6):1494-504.
2009: Erkan Mert; Reiser-Erkan Carolin; Michalski Christoph W; Deucker Stefanie; Sauliunaite Danguole; Streit Sylvia; Esposito Irene; Friess Helmut; Kleeff Jörg
Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma.
Neoplasia (New York, N.Y.) 2009;11(5):497-508.
2009: Ketterer Knut; Kong Bo; Frank Dietwalt; Giese Nathalia A; Bauer Andrea; Hoheisel Jörg; Korc Murray; Kleeff Jörg; Michalski Christoph W; Friess Helmut
Neuromedin U is overexpressed in pancreatic cancer and increases invasiveness via the hepatocyte growth factor c-Met pathway.
Cancer letters 2009;277(1):72-81.
2009: Berberat P O; Künzli B M; Gulbinas A; Ramanauskas T; Kleeff J; Müller M W; Wagner M; Friess H; Büchler M W
An audit of outcomes of a series of periampullary carcinomas.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2009;35(2):187-91.
2009: Müller M W; Assfalg V; Michalski C W; Büchler P; Kleeff J; Friess H
[Middle segmental pancreatic resection: an organ-preserving option for benign lesions]
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2009;80(1):14-21.
2009: Mihaljevic A L; Esposito I; Michalski C W; Kleeff J; Friess H
Defining new pancreatic tumour entities by molecular analysis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2009;9(4):334-9.
2009: Streit Sylvia; Michalski Christoph W; Erkan Mert; Kleeff Jörg; Friess Helmut
Northern blot analysis for detection and quantification of RNA in pancreatic cancer cells and tissues.
Nature protocols 2009;4(1):37-43.
2009: Kolb Armin; Kleeff Jörg; Frohlich Boris; Werner Jens; Friess Helmut; Büchler Markus W
Resection of the intrapancreatic bile duct preserving the pancreas.
Journal of hepato-biliary-pancreatic surgery 2009;16(1):31-4.
2009: Jiang Xiaohua; Abiatari Ivane; Kong Bo; Erkan Mert; De Oliveira Tiago; Giese Nathalia A; Michalski Christoph W; Friess Helmut; Kleeff Jörg
Pancreatic islet and stellate cells are the main sources of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 in pancreatic cancer.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2009;9(1-2):165-72.
2009: Bauer Andrea; Kleeff Jörg; Bier Melanie; Wirtz Martin; Kayed Hany; Esposito Irene; Korc Murray; Hafner Mathias; Hoheisel Jörg D; Friess Helmut
Identification of malignancy factors by analyzing cystic tumors of the pancreas.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2009;9(1-2):34-44.
2008: Reiser-Erkan Carolin; Gaa Jochen; Kleeff Jörg
T1 pancreatic cancer with lymph node metastasis and perineural invasion of the celiac trunk.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2008;6(11):e41-2.
2008: Erkan Mert; Michalski Christoph W; Rieder Simon; Reiser-Erkan Carolin; Abiatari Ivane; Kolb Armin; Giese Nathalia A; Esposito Irene; Friess Helmut; Kleeff Jörg
The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2008;6(10):1155-61.
2008: Loos Martin; Kleeff Jörg; Friess Helmut; Büchler Markus W
Surgical treatment of pancreatic cancer.
Annals of the New York Academy of Sciences 2008;1138():169-80.
2008: Michalski C W; Erkan M; Sauliunaite D; Giese T; Stratmann R; Sartori C; Giese N A; Friess H; Kleeff J
Ex vivo chemosensitivity testing and gene expression profiling predict response towards adjuvant gemcitabine treatment in pancreatic cancer.
British journal of cancer 2008;99(5):760-7.
2008: Reiser-Erkan Carolin; Erkan Mert; Pan Zheng; Bekasi Sandor; Giese Nathalia A; Streit Sylvia; Michalski Christoph W; Friess Helmut; Kleeff Jörg
Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma.
Cancer biology & therapy 2008;7(9):1352-9.
2008: Müller Michael W; Friess Helmut; Leitzbach Sarah; Michalski Christoph W; Berberat Pascal; Ceyhan Güralp O; Hinz Ulf; Ho Choon-Kiat; Köninger Jörg; Kleeff Jörg; Büchler Markus W
Perioperative and follow-up results after central pancreatic head resection (Berne technique) in a consecutive series of patients with chronic pancreatitis.
American journal of surgery 2008;196(3):364-72.
2008: Loos Martin; Giese Nathalia A; Kleeff Jörg; Giese Thomas; Gaida Matthias M; Bergmann Frank; Laschinger Melanie; W Büchler Markus; Friess Helmut
Clinical significance and regulation of the costimulatory molecule B7-H1 in pancreatic cancer.
Cancer letters 2008;268(1):98-109.
2008: Hüser Norbert; Michalski Christoph W; Erkan Mert; Schuster Tibor; Rosenberg Robert; Kleeff Jörg; Friess Helmut
Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery.
Annals of surgery 2008;248(1):52-60.
2008: Kayed Hany; Bekasi Sandor; Keleg Shereen; Welsch Thilo; Esposito Irene; Shimamura Akiko; Michalski Christoph W; Friess Helmut; Kleeff Jörg
Expression of the Shwachman-Bodian-Diamond syndrome (SBDS) protein in human pancreatic cancer and chronic pancreatitis.
Histology and histopathology 2008;23(7):819-26.
2008: Kleeff Jörg; Friess Helmut
Nonmetastatic pancreatic cancer: many trials, little progress.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(18):3100; author reply 3100-a-3101.
2008: Müller Michael W; Dahmen Rolf; Köninger Jörg; Michalski Christoph W; Hinz Ulf; Hartel Mark; Kadmon Martina; Kleeff Jörg; Büchler Markus W; Friess Helmut
Is there an advantage in performing a pancreas-preserving total duodenectomy in duodenal adenomatosis?
American journal of surgery 2008;195(6):741-8.
2008: Esposito Irene; Kleeff Jörg; Bergmann Frank; Reiser Caroline; Herpel Esther; Friess Helmut; Schirmacher Peter; Büchler Markus W
Most pancreatic cancer resections are R1 resections.
Annals of surgical oncology 2008;15(6):1651-60.
2008: Erbel Saskia; Reers Christina; Eckstein Volker W; Kleeff Jörg; Büchler Markus W; Nawroth Peter P; Ritzel Robert A
Proliferation of colo-357 pancreatic carcinoma cells and survival of patients with pancreatic carcinoma are not altered by insulin glargine.
Diabetes care 2008;31(6):1105-11.
2008: Loos Martin; Kleeff Jörg; Friess Helmut; Büchler Markus W
Approaches to localized pancreatic cancer.
Current oncology reports 2008;10(3):212-9.
2008: Schlaeger Christof; Longerich Thomas; Schiller Claudia; Bewerunge Peter; Mehrabi Arianeb; Toedt Grischa; Kleeff Jörg; Ehemann Volker; Eils Roland; Lichter Peter; Schirmacher Peter; Radlwimmer Bernhard
Etiology-dependent molecular mechanisms in human hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 2008;47(2):511-20.
2008: Müller Michael W; Friess Helmut; Köninger Jörg; Martin David; Wente Moritz N; Hinz Ulf; Ceyhan Güralp O; Blaha Pavel; Kleeff Jörg; Büchler Markus W
Factors influencing survival after bypass procedures in patients with advanced pancreatic adenocarcinomas.
American journal of surgery 2008;195(2):221-8.
2008: Michalski Christoph W; Oti Florian E; Erkan Mert; Sauliunaite Danguole; Bergmann Frank; Pacher Pal; Batkai Sandor; Müller Michael W; Giese Nathalia A; Friess Helmut; Kleeff Jörg
Cannabinoids in pancreatic cancer: correlation with survival and pain.
International journal of cancer. Journal international du cancer 2008;122(4):742-50.
2008: Welsch Thilo; Frommhold Klaus; Hinz Ulf; Weigand Markus A; Kleeff Jörg; Friess Helmut; Büchler Markus W; Schmidt Jan
Persisting elevation of C-reactive protein after pancreatic resections can indicate developing inflammatory complications.
Surgery 2008;143(1):20-8.
2008: Jiang Xiaohua; Zhang Weiwei; Kayed Hany; Zheng Pan; Giese Nathalia A; Friess Helmut; Kleeff Jörg
Loss of ONECUT1 expression in human pancreatic cancer cells.
Oncology reports 2008;19(1):157-63.
2008: Michalski Christoph W; Kleeff Jörg; Bachmann Jeannine; Alkhatib Jaber; Erkan Mert; Esposito Irene; Hinz Ulf; Friess Helmut; Büchler Markus W
Second-look operation for unresectable pancreatic ductal adenocarcinoma at a high-volume center.
Annals of surgical oncology 2008;15(1):186-92.
2008: Michalski Christoph W; Erkan Mert; Hüser Norbert; Müller Michael W; Hartel Mark; Friess Helmut; Kleeff Jörg
Resection of primary pancreatic cancer and liver metastasis: a systematic review.
Digestive surgery 2008;25(6):473-80.
2008: Esposito Irene; Born Diana; Bergmann Frank; Longerich Thomas; Welsch Thilo; Giese Nathalia A; Büchler Markus W; Kleeff Jörg; Friess Helmut; Schirmacher Peter
Autoimmune pancreatocholangitis, non-autoimmune pancreatitis and primary sclerosing cholangitis: a comparative morphological and immunological analysis.
PloS one 2008;3(7):e2539.
2008: Michalski Christoph W; Maier Milena; Erkan Mert; Sauliunaite Danguole; Bergmann Frank; Pacher Pal; Batkai Sandor; Giese Nathalia A; Giese Thomas; Friess Helmut; Kleeff Jörg
Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells.
PloS one 2008;3(2):e1701.
2008: Mihaljevic Andre L; Kleeff Jörg; Friess Helmut; Büchler Markus W; Beger Hans G
Surgical approaches to chronic pancreatitis.
Best practice & research. Clinical gastroenterology 2008;22(1):167-81.
2007: Michalski C W; Kleeff J; Büchler M W; Friess H
[Surgical therapy of pancreatic carcinoma]
Zentralblatt für Chirurgie 2007;132(6):W86-92.
2007: Müller Michael W; Friess Helmut; Kleeff Jörg; Dahmen Rolf; Wagner Markus; Hinz Ulf; Breisch-Girbig Daniela; Ceyhan Güralp O; Büchler Markus W
Is there still a role for total pancreatectomy?
Annals of surgery 2007;246(6):966-74; discussion 974-5.
2007: Büchler Markus W; Kleeff Jörg; Friess Helmut
Surgical treatment of pancreatic cancer.
Journal of the American College of Surgeons 2007;205(4 Suppl):S81-6.
2007: Esposito Irene; Seiler Christopher; Bergmann Frank; Kleeff Jörg; Friess Helmut; Schirmacher Peter
Hypothetical progression model of pancreatic cancer with origin in the centroacinar-acinar compartment.
Pancreas 2007;35(3):212-7.
2007: Kayed H; Jiang X; Keleg S; Jesnowski R; Giese T; Berger M R; Esposito I; Löhr M; Friess H; Kleeff J
Regulation and functional role of the Runt-related transcription factor-2 in pancreatic cancer.
British journal of cancer 2007;97(8):1106-15.
2007: Valkovskaya N; Kayed H; Felix K; Hartmann D; Giese N A; Osinsky S P; Friess H; Kleeff J
ADAM8 expression is associated with increased invasiveness and reduced patient survival in pancreatic cancer.
Journal of cellular and molecular medicine 2007;11(5):1162-74.
2007: Kleeff J; Michalski C W; Friess H; Büchler M W
Surgical treatment of pancreatic cancer: the role of adjuvant and multimodal therapies.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2007;33(7):817-23.
2007: Welsch Thilo; Kleeff Jörg; Friess Helmut
Molecular pathogenesis of pancreatic cancer: advances and challenges.
Current molecular medicine 2007;7(5):504-21.
2007: Kleeff Jörg; Beckhove Philipp; Esposito Irene; Herzig Stephan; Huber Peter E; Löhr J Matthias; Friess Helmut
Pancreatic cancer microenvironment.
International journal of cancer. Journal international du cancer 2007;121(4):699-705.
2007: Esposito Irene; Kleeff Jörg; Abiatari Ivane; Shi Xined; Giese Nathalia; Bergmann Frank; Roth Wilfried; Friess Helmut; Schirmacher Peter
Overexpression of cellular inhibitor of apoptosis protein 2 is an early event in the progression of pancreatic cancer.
Journal of clinical pathology 2007;60(8):885-95.
2007: Abdollahi Amir; Schwager Christian; Kleeff Jörg; Esposito Irene; Domhan Sophie; Peschke Peter; Hauser Kai; Hahnfeldt Philip; Hlatky Lynn; Debus Jürgen; Peters Jeffrey M; Friess Helmut; Folkman Judah; Huber Peter E
Transcriptional network governing the angiogenic switch in human pancreatic cancer.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(31):12890-5.
2007: Berberat P O; Ingold H; Gulbinas A; Kleeff J; Müller M W; Gutt C; Weigand M; Friess H; Büchler M W
Fast track--different implications in pancreatic surgery.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2007;11(7):880-7.
2007: Keleg Shereen; Kayed Hany; Jiang Xiaohua; Penzel Roland; Giese Thomas; Büchler Markus W; Friess Helmut; Kleeff Jörg
Adrenomedullin is induced by hypoxia and enhances pancreatic cancer cell invasion.
International journal of cancer. Journal international du cancer 2007;121(1):21-32.
2007: Loos Martin; Bergmann Frank; Bauer Andrea; Hoheisel Jörg D; Esposito Irene; Kleeff Jörg; Schirmacher Peter; Büchler Markus W; Klöppel Günter; Friess Helmut
Solid type clear cell carcinoma of the pancreas: differential diagnosis of an unusual case and review of the literature.
Virchows Archiv : an international journal of pathology 2007;450(6):719-26.
2007: Kleeff Jorg; Friess Helmut; Büchler Markus W
Endoscopic versus surgical treatment for chronic pancreatitis.
The New England journal of medicine 2007;356(20):2103; author reply 2103-4.
2007: Wildi Stefan; Kleeff Jörg; Mayerle Julia; Zimmermann Arthur; Böttinger Erwin P; Wakefield Lalage; Büchler Markus W; Friess Helmut; Korc Murray
Suppression of transforming growth factor beta signalling aborts caerulein induced pancreatitis and eliminates restricted stimulation at high caerulein concentrations.
Gut 2007;56(5):685-92.
2007: Kleeff Jörg; Diener Markus K; Z'graggen Kaspar; Hinz Ulf; Wagner Markus; Bachmann Jeannine; Zehetner Jörg; Müller Michael W; Friess Helmut; Büchler Markus W
Distal pancreatectomy: risk factors for surgical failure in 302 consecutive cases.
Annals of surgery 2007;245(4):573-82.
2007: Kleeff Jörg; Reiser Carolin; Hinz Ulf; Bachmann Jeannine; Debus Jürgen; Jaeger Dirk; Friess Helmut; Büchler Markus W
Surgery for recurrent pancreatic ductal adenocarcinoma.
Annals of surgery 2007;245(4):566-72.
2007: Erkan Mert; Kleeff Jörg; Gorbachevski Andre; Reiser Carolin; Mitkus Tomas; Esposito Irene; Giese Thomas; Büchler Markus W; Giese Nathalia A; Friess Helmut
Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity.
Gastroenterology 2007;132(4):1447-64.
2007: Welsch T; Kleeff J; Esposito I; Büchler Mw; Friess H
Education and imaging. Hepatobiliary and pancreatic: autoimmune pancreatitis.
Journal of gastroenterology and hepatology 2007;22(4):592.
2007: Michalski C W; Kleeff J; Wente M N; Diener M K; Büchler M W; Friess H
Systematic review and meta-analysis of standard and extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer.
The British journal of surgery 2007;94(3):265-73.
2007: Kleeff J; Friess H; Büchler M W
Neoadjuvant therapy for pancreatic cancer.
The British journal of surgery 2007;94(3):261-2.
2007: Kusumawidjaja Grace; Kayed Hany; Giese Nathalia; Bauer Andrea; Erkan Mert; Giese Thomas; Hoheise Jörg D; Friess Helmut; Kleeff Jörg
Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells.
Cancer biology & therapy 2007;6(3):367-76.
2007: Zhang Weiwei; Erkan Mert; Abiatari Ivane; Giese Nathalia A; Felix Klaus; Kayed Hany; Büchler Markus W; Friess Helmut; Kleeff Jörg
Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells.
Cancer biology & therapy 2007;6(2):218-27.
2007: Kolb Armin; Kleeff Jörg; Arnold Nichole; Giese Nathalia A; Giese Thomas; Korc Murray; Friess Helmut
Expression and differential signaling of heregulins in pancreatic cancer cells.
International journal of cancer. Journal international du cancer 2007;120(3):514-23.
2007: Esposito Irene; Kayed Hany; Keleg Shereen; Giese Thomas; Sage E Helene; Schirmacher Peter; Friess Helmut; Kleeff Jörg
Tumor-suppressor function of SPARC-like protein 1/Hevin in pancreatic cancer.
Neoplasia (New York, N.Y.) 2007;9(1):8-17.
2007: Moparthi Satish Babu; Arbman Gunnar; Wallin Asa; Kayed Hany; Kleeff Jörg; Zentgraf Hanswalter; Sun Xiao-Feng
Expression of MAC30 protein is related to survival and biological variables in primary and metastatic colorectal cancers.
International journal of oncology 2007;30(1):91-5.
2007: Shrikhande Shailesh V; Kleeff Jörg; Reiser Carolin; Weitz Jürgen; Hinz Ulf; Esposito Irene; Schmidt Jan; Friess Helmut; Büchler Markus W
Pancreatic resection for M1 pancreatic ductal adenocarcinoma.
Annals of surgical oncology 2007;14(1):118-27.
2007: Kayed Hany; Kleeff Jörg; Keleg Shereen; Felix Klaus; Giese Thomas; Berger Martin R; Büchler Markus W; Friess Helmut
Effects of bone sialoprotein on pancreatic cancer cell growth, invasion and metastasis.
Cancer letters 2007;245(1-2):171-83.
2007: Kayed Hany; Bekasi Sandor; Keleg Shereen; Michalski Christoph W; Giese Thomas; Friess Helmut; Kleeff Jörg
BGLAP is expressed in pancreatic cancer cells and increases their growth and invasion.
Molecular cancer 2007;6():83.
2007: Michalski Christoph W; Gorbachevski Andre; Erkan Mert; Reiser Carolin; Deucker Stefanie; Bergmann Frank; Giese Thomas; Weigand Markus; Giese Nathalia A; Friess Helmut; Kleeff Jörg
Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis.
Journal of translational medicine 2007;5():63.
2007: Kleeff Jörg; Friess Helmut; Büchler Markus W
Dissection of the uncinate process and pancreatic head behind the portal vein using endovascular staplers.
Journal of hepato-biliary-pancreatic surgery 2007;14(5):480-3.
2007: Erkan Mert; Kleeff Jörg; Reiser Carolin; Hinz Ulf; Esposito Irene; Friess Helmut; Büchler Markus W
Preoperative acute pancreatitis in periampullary tumors: implications for surgical management.
Digestion 2007;75(2-3):165-71.
2007: Bachmann Jeannine; Michalski Christoph W; Bergmann Frank; Büchler Markus W; Kleeff Jörg; Friess Helmut
Metastasis of rectal adenocarcinoma to the pancreas. Two case reports and a review of the literature.
JOP : Journal of the pancreas 2007;8(2):214-22.
2006: Müller Michael W; Friess Helmut; Kleeff Jörg; Hinz Ulf; Wente Moritz N; Paramythiotis Daniel; Berberat Pascal O; Ceyhan Güralp O; Büchler Markus W
Middle segmental pancreatic resection: An option to treat benign pancreatic body lesions.
Annals of surgery 2006;244(6):909-18; discussion 918-20.
2006: Zhao Yupei; Shen Songjie; Guo Junchao; Chen Herbert; Greenblatt David Yu; Kleeff Jörg; Liao Quan; Chen Ge; Friess Helmut; Leung Po Sing
Mitogen-activated protein kinases and chemoresistance in pancreatic cancer cells.
The Journal of surgical research 2006;136(2):325-35.
2006: Kleeff Jörg; Friess Helmut
What is the best strategy for the surgical management of patients with necrotizing pancreatitis?
Nature clinical practice. Gastroenterology & hepatology 2006;3(11):616-7.
2006: Kayed Hany; Kleeff Jörg; Keleg Shereen; Jiang Xiaohua; Penzel Roland; Giese Thomas; Zentgraf Hanswalter; Büchler Markus W; Korc Murray; Friess Helmut
Correlation of glypican-1 expression with TGF-beta, BMP, and activin receptors in pancreatic ductal adenocarcinoma.
International journal of oncology 2006;29(5):1139-48.
2006: Welsch Thilo; Kleeff Jörg; Seitz Helmut K; Büchler Peter; Friess Helmut; Büchler Markus W
Update on pancreatic cancer and alcohol-associated risk.
Journal of gastroenterology and hepatology 2006;21 Suppl 3():S69-75.
2006: Abiatari I; Kleeff J; Li J; Felix K; Büchler M W; Friess H
Hsulf-1 regulates growth and invasion of pancreatic cancer cells.
Journal of clinical pathology 2006;59(10):1052-8.
2006: Shrikhande Shailesh V; Kleeff Jörg; Kayed Hany; Keleg Shereen; Reiser Carolin; Giese Thomas; Büchler Markus W; Esposito Irene; Friess Helmut
Silencing of X-linked inhibitor of apoptosis (XIAP) decreases gemcitabine resistance of pancreatic cancer cells.
Anticancer research 2006;26(5A):3265-73.
2006: Welsch Thilo; Kleeff Jörg; Esposito Irene; Büchler Markus W; Friess Helmut
Autoimmune pancreatitis associated with a large pancreatic pseudocyst.
World journal of gastroenterology : WJG 2006;12(36):5904-6.
2006: Kleeff Jörg; Michalski Christoph; Friess Helmut; Büchler Markus W
Pancreatic cancer: from bench to 5-year survival.
Pancreas 2006;33(2):111-8.
2006: Bergmann F; Aulmann S; Wente M N; Penzel R; Esposito I; Kleeff J; Friess H; Schirmacher P
Molecular characterisation of pancreatic ductal adenocarcinoma in patients under 40.
Journal of clinical pathology 2006;59(6):580-4.
2006: Guo Junchao; Kleeff Jörg; Zhao Yupei; Li Junsheng; Giese Thomas; Esposito Irene; Büchler Markus W; Korc Murray; Friess Helmut
Yes-associated protein (YAP65) in relation to Smad7 expression in human pancreatic ductal adenocarcinoma.
International journal of molecular medicine 2006;17(5):761-7.
2006: Esposito I; Penzel R; Chaib-Harrireche M; Barcena U; Bergmann F; Riedl S; Kayed H; Giese N; Kleeff J; Friess H; Schirmacher P
Tenascin C and annexin II expression in the process of pancreatic carcinogenesis.
The Journal of pathology 2006;208(5):673-85.
2006: Kayed Hany; Kleeff Jörg; Osman Tarek; Keleg Shereen; Büchler Markus W; Friess Helmut
Hedgehog signaling in the normal and diseased pancreas.
Pancreas 2006;32(2):119-29.
2006: Shrikhande Shailesh V; Kleeff Jörg; Friess Helmut; Büchler Markus W
Management of pain in small duct chronic pancreatitis.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2006;10(2):227-33.
2006: Kleeff J; Welsch T; Esposito I; Löhr M; Singer R; Büchler M W; Friess H
[Autoimmune pancreatitis--a surgical disease?]
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2006;77(2):154-65.
2006: Gulbinas Antanas; Berberat Pascal O; Dambrauskas Zilvinas; Giese Thomas; Giese Nathalia; Autschbach Frank; Kleeff Joerg; Meuer Stefan; Büchler Markus W; Friess Helmut
Aberrant gata-3 expression in human pancreatic cancer.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(2):161-9.
2006: Schmitz-Winnenthal Friedrich Hubertus; Volk Christine; Helmke Burckhard; Berger Sara; Hinz Ulf; Koch Moritz; Weitz Jürgen; Kleeff Jörg; Friess Helmut; Zöller Margot; Büchler Markus Wolfgang; Z'graggen Kaspar
Expression of cytokeratin-20 in pancreatic cancer: an indicator of poor outcome after R0 resection.
Surgery 2006;139(1):104-8.
2006: Kayed Hany; Kleeff Jörg; Kolb Armin; Ketterer Knut; Keleg Shereen; Felix Klaus; Giese Thomas; Penzel Roland; Zentgraf Hanswalter; Büchler Markus W; Korc Murray; Friess Helmut
FXYD3 is overexpressed in pancreatic ductal adenocarcinoma and influences pancreatic cancer cell growth.
International journal of cancer. Journal international du cancer 2006;118(1):43-54.
2006: Friess Helmut; Kleeff Jörg; Büchler Markus W
Guest editorial.
HPB : the official journal of the International Hepato Pancreato Biliary Association 2006;8(5):323.
2006: Zhang Zhi-Yong; Zhao Zeng-Ren; Adell Gunnar; Jarlsfelt Ingvar; Cui Yong-Xing; Kayed Hany; Kleeff Jorg; Wang Ming-Wei; Sun Xiao-Feng
Expression of MAC30 in rectal cancers with or without preoperative radiotherapy.
Oncology 2006;71(3-4):259-65.
2006: Friess Helmut; Langrehr Jan M; Oettle Helmut; Raedle Jochen; Niedergethmann Marco; Dittrich Christian; Hossfeld Dieter K; Stöger Herbert; Neyns Bart; Herzog Peter; Piedbois Pascal; Dobrowolski Frank; Scheithauer Werner; Hawkins Robert; Katz Frieder; Balcke Peter; Vermorken Jan; van Belle Simon; Davidson Neville; Esteve Albert Abad; Castellano Daniel; Kleeff Jörg; Tempia-Caliera Adrien A; Kovar Andreas; Nippgen Johannes
A randomized multi-center phase II trial of the angiogenesis inhibitor Cilengitide (EMD 121974) and gemcitabine compared with gemcitabine alone in advanced unresectable pancreatic cancer.
BMC cancer 2006;6():285.
2006: Wente Moritz N; Shrikhande Shailesh V; Kleeff Jörg; Müller Michael W; Gutt Carsten N; Büchler Markus W; Friess Helmut
Management of early hemorrhage from pancreatic anastomoses after pancreaticoduodenectomy.
Digestive surgery 2006;23(4):203-8.
2005: Hartel Mark; Wente Moritz N; Hinz Ulf; Kleeff Jörg; Wagner Markus; Müller Michael W; Friess Helmut; Büchler Markus W
Effect of antecolic reconstruction on delayed gastric emptying after the pylorus-preserving Whipple procedure.
Archives of surgery (Chicago, Ill. : 1960) 2005;140(11):1094-9.
2005: Jesnowski Ralf; Fürst Daniel; Ringel Jörg; Chen Ying; Schrödel Andrea; Kleeff Jörg; Kolb Armin; Schareck Wolfgang D; Löhr Matthias
Immortalization of pancreatic stellate cells as an in vitro model of pancreatic fibrosis: deactivation is induced by matrigel and N-acetylcysteine.
Laboratory investigation; a journal of technical methods and pathology 2005;85(10):1276-91.
2005: Bachmann Jeannine; Kleeff Jorg; Bergmann Frank; Shrikhande Shailesh V; Hartschuh Wolfgang; Büchler Markus W; Friess Helmut
Pancreatic metastasis of Merkel cell carcinoma and concomitant insulinoma: case report and literature review.
World journal of surgical oncology 2005;3():58.
2005: Guweidhi Ahmed; Kleeff Jörg; Adwan Hassan; Giese Nathalia A; Wente Moritz N; Giese Thomas; Büchler Markus W; Berger Martin R; Friess Helmut
Osteonectin influences growth and invasion of pancreatic cancer cells.
Annals of surgery 2005;242(2):224-34.
2005: Wente Moritz N; Kleeff Jörg; Büchler Markus W; Wanders Jantien; Cheverton Peter; Langman Stephen; Friess Helmut
DE-310, a macromolecular prodrug of the topoisomerase-I-inhibitor exatecan (DX-8951), in patients with operable solid tumors.
Investigational new drugs 2005;23(4):339-47.
2005: Li Junsheng; Kleeff Jörg; Esposito Irene; Kayed Hany; Felix Klaus; Giese Thomas; Büchler Markus W; Friess Helmut
Expression analysis of PMP22/Gas3 in premalignant and malignant pancreatic lesions.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(7):885-93.
2005: Kolb A; Kleeff J; Guweidhi A; Esposito I; Giese N A; Adwan H; Giese T; Büchler M W; Berger M R; Friess H
Osteopontin influences the invasiveness of pancreatic cancer cells and is increased in neoplastic and inflammatory conditions.
Cancer biology & therapy 2005;4(7):740-6.
2005: Guo Xiao-Zhong; Xu Jian-Hua; Liu Min-Pei; Kleeff Jörg; Ho Choon-Kiat; Ren Li-Nan; Li Hong-Yu; Köninger Jörg; Cui Zhong-Min; Wang Di; Wu Chun-Yan; Zhao Jia-Jun; Friess Helmut
KAI1 inhibits anchorage-dependent and -independent pancreatic cancer cell growth.
Oncology reports 2005;14(1):59-63.
2005: Erkan Mert; Kleeff Jörg; Esposito Irene; Giese Thomas; Ketterer Knut; Büchler Markus W; Giese Nathalla A; Friess Helmut
Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis.
Oncogene 2005;24(27):4421-32.
2005: Wente Moritz N; Kleeff Jörg; Esposito Irene; Hartel Mark; Müller Michael W; Fröhlich Boris E; Büchler Markus W; Friess Helmut
Renal cancer cell metastasis into the pancreas: a single-center experience and overview of the literature.
Pancreas 2005;30(3):218-22.
2005: Kayed Hany; Kleeff Jörg; Esposito Irene; Giese Thomas; Keleg Shereen; Giese Nathalia; Büchler Markus W; Friess Helmut
Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas.
Molecular carcinogenesis 2005;42(4):183-92.
2005: Ho Choon-Kiat; Kleeff Jörg; Friess Helmut; Büchler Markus W
Complications of pancreatic surgery.
HPB : the official journal of the International Hepato Pancreato Biliary Association 2005;7(2):99-108.
2005: Teich Niels; Kleeff Jörg; Lochs Herbert; Mössner Joachim; Keim Volker; Friess Helmut; Ockenga Johann
The presence of the proteolysis-inducing factor in urine does not predict the malignancy of a pancreatic tumour.
BMC gastroenterology 2005;5():20.
2005: Li Junsheng; Kleeff Jörg; Abiatari Ivane; Kayed Hany; Giese Nathalia A; Felix Klaus; Giese Thomas; Büchler Markus W; Friess Helmut
Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer.
Molecular cancer 2005;4(1):14.
2004: Ryschich E; Cebotari O; Fabian O V; Autschbach F; Kleeff J; Friess H; Bierhaus A; Büchler M W; Schmidt J
Loss of heterozygosity in the HLA class I region in human pancreatic cancer.
Tissue antigens 2004;64(6):696-702.
2004: Kleeff Jorg; Friess Helmut; Büchler Markus W
What is the most accurate test to differentiate pancreatic cystic neoplasms?
Nature clinical practice. Gastroenterology & hepatology 2004;1(1):18-9.
2004: Kayed H; Kleeff J; Ding J; Hammer J; Giese T; Zentgraf H; Büchler M W; Friess H
Expression analysis of MAC30 in human pancreatic cancer and tumors of the gastrointestinal tract.
Histology and histopathology 2004;19(4):1021-31.
2004: Guweidhi Ahmed; Kleeff Jörg; Giese Nathalia; El Fitori Jamael; Ketterer Knut; Giese Thomas; Büchler Markus W; Korc Murray; Friess Helmut
Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis.
Carcinogenesis 2004;25(9):1575-85.
2004: Li Junsheng; Kleeff Jörg; Kayed Hany; Felix Klaus; Penzel Roland; Büchler Markus W; Korc Murray; Friess Helmut
Glypican-1 antisense transfection modulates TGF-beta-dependent signaling in Colo-357 pancreatic cancer cells.
Biochemical and biophysical research communications 2004;320(4):1148-55.
2004: Li Junsheng; Kleeff Jörg; Giese Nathalia; Büchler Markus W; Korc Murray; Friess Helmut
Gefitinib ('Iressa', ZD1839), a selective epidermal growth factor receptor tyrosine kinase inhibitor, inhibits pancreatic cancer cell growth, invasion, and colony formation.
International journal of oncology 2004;25(1):203-10.
2004: Kayed Hany; Kleeff Jörg; Keleg Shereen; Guo Junchau; Ketterer Knut; Berberat Pascal O; Giese Nathalia; Esposito Irene; Giese Thomas; Büchler Markus W; Friess Helmut
Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer.
International journal of cancer. Journal international du cancer 2004;110(5):668-76.
2004: Arnold Nichole Boyer; Ketterer Knut; Kleeff Jörg; Friess Helmut; Büchler Markus W; Korc Murray
Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer.
Cancer research 2004;64(10):3599-606.
2004: Wirtz Martin; Kleeff Jörg; Swoboda Stefanie; Halaceli Irfan; Geiss Heiko K; Hoppe-Tichy Torsten; Büchler Markus W; Friess Helmut
Moxifloxacin penetration into human gastrointestinal tissues.
The Journal of antimicrobial chemotherapy 2004;53(5):875-7.
2004: Esposito Irene; Bauer Andrea; Hoheisel Jörg D; Kleeff Jörg; Friess Helmut; Bergmann Frank; Rieker Ralf J; Otto Herwart F; Klöppel Günter; Penzel Roland
Microcystic tubulopapillary carcinoma of the pancreas: a new tumor entity?
Virchows Archiv : an international journal of pathology 2004;444(5):447-53.
2004: Li J; Kleeff J; Guweidhi A; Esposito I; Berberat P O; Giese T; Büchler M W; Friess H
RUNX3 expression in primary and metastatic pancreatic cancer.
Journal of clinical pathology 2004;57(3):294-9.
2004: Xiao Yi; Kleeff Jörg; Guo Junchao; Gazdhar Amiq; Liao Quan; Di Cesare Paul E; Büchler Markus W; Friess Helmut
Cartilage oligomeric matrix protein expression in hepatocellular carcinoma and the cirrhotic liver.
Journal of gastroenterology and hepatology 2004;19(3):296-302.
2004: Guo Junchao; Kleeff Jörg; Li Junsheng; Ding Jiayi; Hammer Jürgen; Zhao Yupei; Giese Thomas; Korc Murray; Büchler Markus W; Friess Helmut
Expression and functional significance of CDC25B in human pancreatic ductal adenocarcinoma.
Oncogene 2004;23(1):71-81.
2004: Kleeff Jörg; Kothari Nayantara H; Friess Helmut; Fan Hung; Korc Murray
Adenovirus-mediated transfer of a truncated fibroblast growth factor (FGF) type I receptor blocks FGF-2 signaling in multiple pancreatic cancer cell lines.
Pancreas 2004;28(1):25-30.
2004: Paramythiotis Daniel; Kleeff Jörg; Wirtz Martin; Friess Helmut; Büchler Markus W
Still any role for transduodenal local excision in tumors of the papilla of Vater?
Journal of hepato-biliary-pancreatic surgery 2004;11(4):239-44.
2003: Friess Helmut; Kleeff Jörg; Büchler Markus W
Molecular pathophysiology of chronic pancreatitis--an update.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2003;7(8):943-5.
2003: Li Junsheng; Kleeff Jörg; Guo Junchao; Fischer Lars; Giese Nathalia; Büchler Markus W; Friess Helmut
Effects of STI571 (gleevec) on pancreatic cancer cell growth.
Molecular cancer 2003;2():32.
2003: Kayed H; Kleeff J; Keleg S; Büchler M W; Friess H
Distribution of Indian hedgehog and its receptors patched and smoothened in human chronic pancreatitis.
The Journal of endocrinology 2003;178(3):467-78.
2003: Reubi Jean Claude; Waser Beatrice; Gugger Mathias; Friess Helmut; Kleeff Jörg; Kayed Hany; Büchler Markus W; Laissue Jean A
Distribution of CCK1 and CCK2 receptors in normal and diseased human pancreatic tissue.
Gastroenterology 2003;125(1):98-106.
2003: Friess H; Ding J; Kleeff J; Fenkell L; Rosinski J A; Guweidhi A; Reidhaar-Olson J F; Korc M; Hammer J; Büchler M W
Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer.
Cellular and molecular life sciences : CMLS 2003;60(6):1180-99.
2003: Liao Quan; Guo Junchao; Kleeff Jörg; Zimmermann Arthur; Büchler Markus W; Korc Murray; Friess Helmut
Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells.
Gastroenterology 2003;124(7):1830-45.
2003: Shi Xin; Kleeff Jörg; Zhu Zhao-Wen; Schmied Bruno; Tang Wen-Hao; Zimmermann Arthur; Buchler Markus W; Friess Helmut
Gene-expression analysis of single cells-nested polymerase chain reaction after laser microdissection.
World journal of gastroenterology : WJG 2003;9(6):1337-41.
2003: Lukyanchuk Vitaliy V; Friess Helmut; Kleeff Jorg; Osinsky Sergej P; Ayuni Erick; Candinas Daniel; Roggo Antoine
Detection of circulating tumor cells by cytokeratin 20 and prostate stem cell antigen RT-PCR in blood of patients with gastrointestinal cancers.
Anticancer research 2003;23(3B):2711-6.
2003: Liao Quan; Zhao Yu-pei; Kleeff Jorg; Xiao Yi; Zimmermann Arthur; Buchler Markus W; Friess Helmut
[Preferential expression of cartilage oligomeric matrix protein in degenerating acinar cells in chronic pancreatitis and in chronic pancreatitis-like lesions]
Zhonghua wai ke za zhi [Chinese journal of surgery] 2003;41(5):328-31.
2003: Liao Q; Kleeff J; Xiao Y; Guweidhi A; Schambony A; Töpfer-Petersen E; Zimmermann A; Büchler M W; Friess H
Preferential expression of cystein-rich secretory protein-3 (CRISP-3) in chronic pancreatitis.
Histology and histopathology 2003;18(2):425-33.
2003: Xu Zhong-Wei; Kleeff Jörg; Friess Helmut; Büchler Markus W; Solioz Marc
Synergistic cytotoxic effect of TRAIL and gemcitabine in pancreatic cancer cells.
Anticancer research 2003;23(1A):251-8.
2003: Paramythiotis D; Kleeff J; Schmidt J; Büchler Mw; Friess H
Detection of oncogenes in chronic pancreatitis.
HPB : the official journal of the International Hepato Pancreato Biliary Association 2003;5(4):214-25.
2003: Kleeff J; Friess H; Büchler M W
How Helicobacter Pylori changed the life of surgeons.
Digestive surgery 2003;20(2):93-102.
2003: Shrikhande Shailesh; Kleeff Jörg; Adyanthaya Kishor; Zimmermann Arthur; Shrikhande Vinayak
Management of hepatobiliary cystadenocarcinoma.
Digestive surgery 2003;20(1):60-3.
2002: Fischer L; Kleeff J; Friess H; Büchler M W
[Surgical management of pancreatic carcinoma]
Zeitschrift für Gastroenterologie 2002;40 Suppl 2():64-7.
2002: Esposito Irene; Kleeff Jörg; Bischoff Stephan C; Fischer Lars; Collecchi Paola; Iorio Mariacarla; Bevilacqua Generoso; Büchler Markus W; Friess Helmut
The stem cell factor-c-kit system and mast cells in human pancreatic cancer.
Laboratory investigation; a journal of technical methods and pathology 2002;82(11):1481-92.
2002: Zhu Zhaowen; Kleeff Jörg; Kayed Hany; Wang Li; Korc Murray; Büchler Markus W; Friess Helmut
Nerve growth factor and enhancement of proliferation, invasion, and tumorigenicity of pancreatic cancer cells.
Molecular carcinogenesis 2002;35(3):138-47.
2002: Schneider Dominik; Kleeff Jörg; Berberat Pascal O; Zhu Zhaowen; Korc Murray; Friess Helmut; Büchler Markus W
Induction and expression of betaig-h3 in pancreatic cancer cells.
Biochimica et biophysica acta 2002;1588(1):1-6.
2002: Kleeff Jörg; Huang Yong; Mok Samuel C; Zimmermann Arthur; Friess Helmut; Büchler Markus W
Down-regulation of DOC-2 in colorectal cancer points to its role as a tumor suppressor in this malignancy.
Diseases of the colon and rectum 2002;45(9):1242-8.
2002: Koliopanos Alexander; Kleeff Jörg; Xiao Yi; Safe Stephen; Zimmermann Arthur; Büchler Markus W; Friess Helmut
Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer.
Oncogene 2002;21(39):6059-70.
2002: Zhu Zhaowen; Friess Helmut; Kleeff Jörg; Wang Li; Wirtz Martin; Zimmermann Arthur; Korc Murray; Büchler Markus W
Glypican-3 expression is markedly decreased in human gastric cancer but not in esophageal cancer.
American journal of surgery 2002;184(1):78-83.
2002: Kleeff Jörg; Fukahi Kimi; Lopez Martha E; Friess Helmut; Büchler Markus W; Sosnowski Barbara A; Korc Murray
Targeting of suicide gene delivery in pancreatic cancer cells via FGF receptors.
Cancer gene therapy 2002;9(6):522-32.
2002: Liu Sheng-Li; Friess Helmut; Kleeff Jörg; Ji Zheng-Ling; Büchler Markus W
Surgical approaches for resection of pancreatic cancer: an overview.
Hepatobiliary & pancreatic diseases international : HBPD INT 2002;1(1):118-25.
2002: Shrikhande Shailesh; Friess Helmut; Kleeff Jörg; Tempia Adrien; Zimmermann Arthur; Borner Markus; Büchler Markus W
Bile duct infarction following intraarterial hepatic chemotherapy mimicking multiple liver metastasis: report of a case and review of the literature.
Digestive diseases and sciences 2002;47(2):338-44.
2002: Künzli Beat M; Berberat Pascal O; Zhu Zhaowhen W; Martignoni Marcus; Kleeff Jörg; Tempia-Caliera Adrien A; Fukuda Minoru; Zimmermann Arthur; Friess Helmut; Büchler Markus W
Influences of the lysosomal associated membrane proteins (Lamp-1, Lamp-2) and Mac-2 binding protein (Mac-2-BP) on the prognosis of pancreatic carcinoma.
Cancer 2002;94(1):228-39.
2002: Kayed Hany; Müller Michael; Kleeff Jörg; Bockman Dale E; Büchler Markus W; Friess Helmut
Molecular alterations in chronic pancreatitis.
Journal of hepato-biliary-pancreatic surgery 2002;9(6):653-8.
2002: Shi Xin; Liu Shengli; Kleeff Jörg; Friess Helmut; Büchler Markus W
Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes.
Oncology 2002;62(4):354-62.
2001: Friess H; Ding J; Kleeff J; Liao Q; Berberat P O; Hammer J; Büchler M W
Identification of disease-specific genes in chronic pancreatitis using DNA array technology.
Annals of surgery 2001;234(6):769-78; discussion 778-9.
2001: Esposito I; Friess H; Kappeler A; Shrikhande S; Kleeff J; Ramesh H; Zimmermann A; Büchler M W
Mast cell distribution and activation in chronic pancreatitis.
Human pathology 2001;32(11):1174-83.
2001: Xu Z; Friess H; Solioz M; Aebi S; Korc M; Kleeff J; Büchler M W
Bcl-x(L) antisense oligonucleotides induce apoptosis and increase sensitivity of pancreatic cancer cells to gemcitabine.
International journal of cancer. Journal international du cancer 2001;94(2):268-74.
2001: Kleeff J; Shi X; Bode H P; Hoover K; Shrikhande S; Bryant P J; Korc M; Büchler M W; Friess H
Altered expression and localization of the tight junction protein ZO-1 in primary and metastatic pancreatic cancer.
Pancreas 2001;23(3):259-65.
2001: Liao Q; Friess H; Kleeff J; Büchler M W
Differential expression of TRAIL-R3 and TRAIL-R4 in human pancreatic cancer.
Anticancer research 2001;21(5):3153-9.
2001: Wildi S; Kleeff J; Maruyama H; Maurer C A; Büchler M W; Korc M
Overexpression of activin A in stage IV colorectal cancer.
Gut 2001;49(3):409-17.
2001: Liao Q; Ozawa F; Friess H; Zimmermann A; Takayama S; Reed J C; Kleeff J; Büchler M W
The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines.
FEBS letters 2001;503(2-3):151-7.
2001: Matsuda K; Maruyama H; Guo F; Kleeff J; Itakura J; Matsumoto Y; Lander A D; Korc M
Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cells.
Cancer research 2001;61(14):5562-9.
2001: Huang Y; Friess H; Kleeff J; Esposito I; Zhu Z; Liu S; Mok S C; Zimmermann A; Büchler M W
Doc-2/hDab2 expression is up-regulated in primary pancreatic cancer but reduced in metastasis.
Laboratory investigation; a journal of technical methods and pathology 2001;81(6):863-73.
2001: Koliopanos A; Friess H; Kleeff J; Shi X; Liao Q; Pecker I; Vlodavsky I; Zimmermann A; Büchler M W
Heparanase expression in primary and metastatic pancreatic cancer.
Cancer research 2001;61(12):4655-9.
2001: Zhu Z W; Friess H; Wang L; Abou-Shady M; Zimmermann A; Lander A D; Korc M; Kleeff J; Büchler M W
Enhanced glypican-3 expression differentiates the majority of hepatocellular carcinomas from benign hepatic disorders.
Gut 2001;48(4):558-64.
2001: Ozawa F; Friess H; Kleeff J; Xu Z W; Zimmermann A; Sheikh M S; Büchler M W
Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer.
Cancer letters 2001;163(1):71-81.
2001: Zhu Z W; Friess H; Wang L; Bogardus T; Korc M; Kleeff J; Büchler M W
Nerve growth factor exerts differential effects on the growth of human pancreatic cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(1):105-12.
2001: Kekis P B; Friess H; Kleeff J; Büchler M W
Timing and extent of surgical intervention in patients from hereditary pancreatic cancer kindreds.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2001;1(5):525-30.
2001: Shi X; Friess H; Kleeff J; Ozawa F; Büchler M W
Pancreatic cancer: factors regulating tumor development, maintenance and metastasis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2001;1(5):517-24.
2001: Shrikhande S; Kleeff J; Zimmermann A; Friess H; Büchler M W
Co-existent chronic pancreatitis and pancreatic neuroendocrine tumor. Case report and review of the literature.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2001;1(2):117-22.
2001: Koliopanos A; Friess H; Kleeff J; Roggo A; Zimmermann A; Büchler M W
Cyclooxygenase 2 expression in chronic pancreatitis: correlation with stage of the disease and diabetes mellitus.
Digestion 2001;64(4):240-7.
2001: Ozawa F; Friess H; Tempia-Caliera A; Kleeff J; Büchler M W
Growth factors and their receptors in pancreatic cancer.
Teratogenesis, carcinogenesis, and mutagenesis 2001;21(1):27-44.
2000: Lu Z; Kleeff J; Shrikhande S; Zimmermann T; Korc M; Friess H; Büchler M W
Expression of the multidrug-resistance 1 (MDR1) gene and prognosis in human pancreatic cancer.
Pancreas 2000;21(3):240-7.
2000: Conejo J R; Kleeff J; Koliopanos A; Matsuda K; Zhu Z W; Goecke H; Bicheng N; Zimmermann A; Korc M; Friess H; Büchler M W
Syndecan-1 expression is up-regulated in pancreatic but not in other gastrointestinal cancers.
International journal of cancer. Journal international du cancer 2000;88(1):12-20.
2000: Shrikhande S; Friess H; Issenegger C; Martignoni M E; Yong H; Gloor B; Yeates R; Kleeff J; Büchler M W
Fluconazole penetration into the pancreas.
Antimicrobial agents and chemotherapy 2000;44(9):2569-71.
2000: Zhu Z; Kleeff J; Friess H; Wang L; Zimmermann A; Yarden Y; Büchler M W; Korc M
Epiregulin is Up-regulated in pancreatic cancer and stimulates pancreatic cancer cell growth.
Biochemical and biophysical research communications 2000;273(3):1019-24.
2000: Ozawa F; Friess H; Zimmermann A; Kleeff J; Büchler M W
Enhanced expression of Silencer of death domains (SODD/BAG-4) in pancreatic cancer.
Biochemical and biophysical research communications 2000;271(2):409-13.
2000: Kleeff J; Kornmann M; Sawhney H; Korc M
Actinomycin D induces apoptosis and inhibits growth of pancreatic cancer cells.
International journal of cancer. Journal international du cancer 2000;86(3):399-407.
2000: Kornmann M; Ishiwata T; Kleeff J; Beger H G; Korc M
Fas and Fas-ligand expression in human pancreatic cancer.
Annals of surgery 2000;231(3):368-79.
2000: Kleeff J; Friess H; Korc M; Büchler M W
Chronic pancreatitis: pathogenesis and molecular aspects.
Annali italiani di chirurgia 2000;71(1):3-10.
2000: Kleeff J; Friess H; Berberat P O; Martignoni M E; Z'graggen K; Büchler M W
Pancreatic cancer--new aspects of molecular biology research.
Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera 2000;6(5):231-4.
1999: Wagner M; Kleeff J; Friess H; Büchler M W; Korc M
Enhanced expression of the type II transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer.
Pancreas 1999;19(4):370-6.
1999: Wildi S; Kleeff J; Maruyama H; Maurer C A; Friess H; Büchler M W; Lander A D; Korc M
Characterization of cytokeratin 20 expression in pancreatic and colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10):2840-7.
1999: Kleeff J; Wildi S; Kumbasar A; Friess H; Lander A D; Korc M
Stable transfection of a glypican-1 antisense construct decreases tumorigenicity in PANC-1 pancreatic carcinoma cells.
Pancreas 1999;19(3):281-8.
1999: Kleeff J; Friess H; Simon P; Susmallian S; Büchler P; Zimmermann A; Büchler M W; Korc M
Overexpression of Smad2 and colocalization with TGF-beta1 in human pancreatic cancer.
Digestive diseases and sciences 1999;44(9):1793-802.
1999: Kleeff J; Ishiwata T; Maruyama H; Friess H; Truong P; Büchler M W; Falb D; Korc M
The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer.
Oncogene 1999;18(39):5363-72.
1999: Maruyama H; Kleeff J; Wildi S; Friess H; Büchler M W; Israel M A; Korc M
Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis.
The American journal of pathology 1999;155(3):815-22.
1999: Kleeff J; Wildi S; Friess H; Korc M
Ligand induced upregulation of the type II transforming growth factor (TGF-beta) receptor enhances TGF-beta responsiveness in COLO-357 cells.
Pancreas 1999;18(4):364-70.
1999: Kleeff J; Kusama T; Rossi D L; Ishiwata T; Maruyama H; Friess H; Büchler M W; Zlotnik A; Korc M
Detection and localization of Mip-3alpha/LARC/Exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer.
International journal of cancer. Journal international du cancer 1999;81(4):650-7.
1999: Kleeff J; Maruyama H; Ishiwata T; Sawhney H; Friess H; Büchler M W; Korc M
Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo.
Gastroenterology 1999;116(5):1202-16.
1999: Friess H; Kleeff J; Kulli C; Wagner M; Sawhney H; Büchler M W
The impact of different types of surgery in pancreatic cancer.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1999;25(2):124-31.
1999: Kleeff J; Maruyama H; Friess H; Büchler M W; Falb D; Korc M
Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer.
Biochemical and biophysical research communications 1999;255(2):268-73.
1999: Kornmann M; Kleeff J; Debinski W; Korc M
Pancreatic cancer cells express interleukin-13 and -4 receptors, and their growth is inhibited by Pseudomonas exotoxin coupled to interleukin-13 and -4.
Anticancer research 1999;19(1A):125-31.
1999: Berberat P O; Friess H; Kleeff J; Uhl W; Büchler M W
Prevention and treatment of complications in pancreatic cancer surgery.
Digestive surgery 1999;16(4):327-36.
1999: Friess H; Kleeff J; Korc M; Büchler M W
Molecular aspects of pancreatic cancer and future perspectives.
Digestive surgery 1999;16(4):281-90.
1998: Kleeff J; Ishiwata T; Kumbasar A; Friess H; Büchler M W; Lander A D; Korc M
The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer.
The Journal of clinical investigation 1998;102(9):1662-73.
1998: Wagner M; Kleeff J; Lopez M E; Bockman I; Massaqué J; Korc M
Transfection of the type I TGF-beta receptor restores TGF-beta responsiveness in pancreatic cancer.
International journal of cancer. Journal international du cancer 1998;78(2):255-60.
1998: Kleeff J; Ishiwata T; Friess H; Büchler M W; Israel M A; Korc M
The helix-loop-helix protein Id2 is overexpressed in human pancreatic cancer.
Cancer research 1998;58(17):3769-72.
1998: Kleeff J; Ishiwata T; Friess H; Büchler M W; Korc M
Concomitant over-expression of activin/inhibin beta subunits and their receptors in human pancreatic cancer.
International journal of cancer. Journal international du cancer 1998;77(6):860-8.
1998: Friess H; Kleeff J; Isenmann R; Malfertheiner P; Büchler M W
Adaptation of the human pancreas to inhibition of luminal proteolytic activity.
Gastroenterology 1998;115(2):388-96.
1998: Friess H; Duarte R; Kleeff J; Fukuda A; Tang W H; Graber H; Schilling M; Zimmermann A; Korc M; Büchler M W
The plasminogen activator/plasmin system is up-regulated after acute necrotizing pancreatitis in human beings.
Surgery 1998;124(1):79-86.
1998: Friess H; Kleeff J; Silva J C; Sadowski C; Baer H U; Büchler M W
The role of diagnostic laparoscopy in pancreatic and periampullary malignancies.
Journal of the American College of Surgeons 1998;186(6):675-82.
1998: Friess H; Kleeff J; Malfertheiner P; Müller M W; Homuth K; Büchler M W
Influence of high-dose pancreatic enzyme treatment on pancreatic function in healthy volunteers.
International journal of pancreatology : official journal of the International Association of Pancreatology 1998;23(2):115-23.
1998: Kleeff J; Korc M
Up-regulation of transforming growth factor (TGF)-beta receptors by TGF-beta1 in COLO-357 cells.
The Journal of biological chemistry 1998;273(13):7495-500.
1997: Müller M W; Friess H; Beger H G; Kleeff J; Lauterburg B; Glasbrenner B; Riepl R L; Büchler M W
Gastric emptying following pylorus-preserving Whipple and duodenum-preserving pancreatic head resection in patients with chronic pancreatitis.
American journal of surgery 1997;173(4):257-63.
1997: Friess H; Kleeff J; Gumbs A; Büchler M W
Molecular versus conventional markers in pancreatic cancer.
Digestion 1997;58(6):557-63.
1996: Friess H; Isenmann R; Berberat P; Kleeff J; Büchler M W
[Prognosis in pancreatic carcinoma]
Therapeutische Umschau. Revue thérapeutique 1996;53(5):401-7.

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