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Andres Klein-Szanto

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Hoi Yee Chow; Sergio G Duron; J Silvio Gutkind; Klaus P Hoeflich; Zahara M Jaffer; Adrian M Jubb; Andres J P Klein-Szanto; Jennifer N Koch; Marie O'Farrell; Dina Stepanova; Kathy Q Cai; David A Campbell; Jonathan Chernoff
p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.
Laura Pontano Vaites; Mariusz A Wasik; Olena Barbash; Andres J P Klein-Szanto; Eric K Lee; Zhaorui Lian; Darshan Roy; Anil K Rustgi; J Alan Diehl
The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation.
Jacky G Goetz; Patricia J Keely; Andres J P Klein-Szanto; Juan José Lazcano; Susana Minguet; Inmaculada Navarro-Lérida; Teresa Osteso-Ibáñez; Teijo Pellinen; Rafael Samaniego; Paloma Sánchez-Mateos; Marta Tello; Enrique Calvo; Ana Cerezo; Edna Cukierman; Asier Echarri; Ricardo Garcia; Miguel A Del Pozo
Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis.

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All Publications

2012: Hoi Yee Chow; Sergio G Duron; J Silvio Gutkind; Klaus P Hoeflich; Zahara M Jaffer; Adrian M Jubb; Andres J P Klein-Szanto; Jennifer N Koch; Marie O'Farrell; Dina Stepanova; Kathy Q Cai; David A Campbell; Jonathan Chernoff
p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.
Cancer research 2012;72(22):5966-75.
2011: Laura Pontano Vaites; Mariusz A Wasik; Olena Barbash; Andres J P Klein-Szanto; Eric K Lee; Zhaorui Lian; Darshan Roy; Anil K Rustgi; J Alan Diehl
The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation.
Molecular and cellular biology 2011;31(22):4513-23.
2011: Jacky G Goetz; Patricia J Keely; Andres J P Klein-Szanto; Juan José Lazcano; Susana Minguet; Inmaculada Navarro-Lérida; Teresa Osteso-Ibáñez; Teijo Pellinen; Rafael Samaniego; Paloma Sánchez-Mateos; Marta Tello; Enrique Calvo; Ana Cerezo; Edna Cukierman; Asier Echarri; Ricardo Garcia; Miguel A Del Pozo
Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis.
Cell 2011;146(1):148-63.
2011: Stephen I Rudnick; Jianlong Lou; Calvin Shaller; Yong Tang; Andres J P Klein-Szanto; Louis M Weiner; James D Marks; Gregory P Adams
Influence of affinity and antigen internalization on the uptake and penetration of Anti-HER2 antibodies in solid tumors.
Cancer research 2011;71(6):2250-9.
2011: Ekaterina G Shatalova; Andres J P Klein-Szanto; Karthik Devarajan; Edna Cukierman; Margie L Clapper
Estrogen and cytochrome P450 1B1 contribute to both early- and late-stage head and neck carcinogenesis.
Cancer prevention research (Philadelphia, Pa.) 2011;4(1):107-15.
2010: Mitsuteru Natsuizaka; Shinya Ohashi; Gabrielle S Wong; Azal Ahmadi; Ross A Kalman; Daniela Budo; Andres J P Klein-Szanto; Meenhard Herlyn; J Alan Diehl; Hiroshi Nakagawa
Insulin-like growth factor-binding protein-3 promotes transforming growth factor-{beta}1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells.
Carcinogenesis 2010;31(8):1344-53.
2010: Katharine D Grugan; Charles G Miller; Yao Yao; Carmen Z Michaylira; Shinya Ohashi; Andres J P Klein-Szanto; J Alan Diehl; Meenhard Herlyn; May Han; Hiroshi Nakagawa; Anil K Rustgi
Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(24):11026-31.
2010: James J Lee; Mitsuteru Natsuizaka; Shinya Ohashi; Gabrielle S Wong; Munenori Takaoka; Carmen Z Michaylira; Daniela Budo; John W Tobias; Michiyuki Kanai; Yasuhiro Shirakawa; Yoshio Naomoto; Andres J P Klein-Szanto; Volker H Haase; Hiroshi Nakagawa
Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis.
Carcinogenesis 2010;31(3):427-34.
2010: Jian Fu; Fang Jin; Jirong Zhang; Kathryn Fong; Daniel E Bassi; Ricardo Lopez De Cicco; Divya Ramaraju; Karl-Heinz Braunewell; Claudio Conti; Fernando Benavides; Andres J P Klein-Szanto
VILIP-1 expression in vivo results in decreased mouse skin keratinocyte proliferation and tumor development.
PloS one 2010;5(4):e10196.
2008: Russell J Schilder; Michael W Sill; Roger B Lee; Tanya J Shaw; Mary K Senterman; Andres J P Klein-Szanto; Zoe Miner; Barbara C Vanderhyden
Phase II evaluation of imatinib mesylate in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(20):3418-25.
2008: Qihong Huang; Kiranmai Gumireddy; Mariette Schrier; Carlos le Sage; Remco Nagel; Suresh Nair; David A Egan; Anping Li; Guanghua Huang; Andres J P Klein-Szanto; Phyllis A Gimotty; Dionyssios Katsaros; George Coukos; Lin Zhang; Ellen Puré; Reuven Agami
The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis.
Nature cell biology 2008;10(2):202-10.
2008: Jian Fu; Kathryn Fong; Alfonso Bellacosa; Eric Ross; Sinoula Apostolou; Daniel E Bassi; Fang Jin; Jirong Zhang; Paul Cairns; Inmaculada Ibañez de Caceres; Karl-Heinz Braunewell; Andres J P Klein-Szanto
VILIP-1 downregulation in non-small cell lung carcinomas: mechanisms and prediction of survival.
PloS one 2008;3(2):e1698.
2008: Niklas Finnberg; Andres J P Klein-Szanto; Wafik S El-Deiry
TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis.
The Journal of clinical investigation 2008;118(1):111-23.
2007: Priya Aggarwal; Matthew D Lessie; Douglas I Lin; Laura Pontano; Andrew B Gladden; Beth Nuskey; Ami Goradia; Mariusz A Wasik; Andres J P Klein-Szanto; Anil K Rustgi; Craig H Bassing; J Alan Diehl
Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication.
Genes & development 2007;21(22):2908-22.
2007: Takaomi Okawa; Carmen Z Michaylira; Jiri Kalabis; Douglas B Stairs; Hiroshi Nakagawa; Claudia D Andl; Cameron N Johnstone; Andres J P Klein-Szanto; Wafik S El-Deiry; Edna Cukierman; Meenhard Herlyn; Anil K Rustgi
The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation.
Genes & development 2007;21(21):2788-803.
2007: Ricardo López de Cicco; Daniel E Bassi; Fernando Benavides; Claudio J Conti; Andres J P Klein-Szanto
Inhibition of proprotein convertases: approaches to block squamous carcinoma development and progression.
Molecular carcinogenesis 2007;46(8):654-9.
2007: Linda L Garland; Cathryn Rankin; David R Gandara; Saul E Rivkin; Katherine M Scott; Raymond B Nagle; Andres J P Klein-Szanto; Joseph R Testa; Deborah A Altomare; Ernest C Borden
Phase II study of erlotinib in patients with malignant pleural mesothelioma: a Southwest Oncology Group Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(17):2406-13.
2007: Kiranmai Gumireddy; Fangxian Sun; Andres J P Klein-Szanto; Jonathan M Gibbins; Phyllis A Gimotty; Aleister J Saunders; Peter G Schultz; Qihong Huang
In vivo selection for metastasis promoting genes in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(16):6696-701.
2007: Munenori Takaoka; Seok-Hyun Kim; Takaomi Okawa; Carmen Z Michaylira; Douglas B Stairs; Cameron N Johnstone; Claudia D Andl; Ben Rhoades; James J Lee; Andres J P Klein-Szanto; Wafik S El-Deiry; Hiroshi Nakagawa
IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms.
Cancer biology & therapy 2007;6(4):534-40.
2007: Ying Yu; Jinjin Fan; Yiqun Hui; Carol A Rouzer; Lawrence J Marnett; Andres J P Klein-Szanto; garret fitzgerald; Colin D Funk
Targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality.
The Journal of biological chemistry 2007;282(2):1498-506.
2007: Robert E Page; Andres J P Klein-Szanto; Samuel Litwin; Emmanuelle Nicolas; Raid Al-Jumaily; Peter Alexander; Andrew K Godwin; Eric A Ross; Russell J Schilder; Daniel E Bassi
Increased expression of the pro-protein convertase furin predicts decreased survival in ovarian cancer.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(4):289-99.
2007: Victoria A Robb; Magdalena Karbowniczek; Andres J P Klein-Szanto; Elizabeth Petri Henske
Activation of the mTOR signaling pathway in renal clear cell carcinoma.
The Journal of urology 2007;177(1):346-52.
2007: Walter M Klein; Bryan P Wu; Shuping Zhao; Hong Wu; Andres J P Klein-Szanto; Steven R Tahan
Increased expression of stem cell markers in malignant melanoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(1):102-7.
2006: Douglas I Lin; Olena Barbash; K G Suresh Kumar; Jason D. Weber; J Wade Harper; Andres J P Klein-Szanto; Anil K Rustgi; Serge Y Fuchs; J Alan Diehl
Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex.
Molecular cell 2006;24(3):355-66.
2006: Seok-Hyun Kim; Hiroshi Nakagawa; Arunasalam Navaraj; Yoshio Naomoto; Andres J P Klein-Szanto; Anil K Rustgi; Wafik S El-Deiry
Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras.
Cancer research 2006;66(21):10415-24.
2006: Carla Wickborn; Andres J P Klein-Szanto; Peter M Schlag; Karl-Heinz Braunewell
Correlation of visinin-like-protein-1 expression with clinicopathological features in squamous cell carcinoma of the esophagus.
Molecular carcinogenesis 2006;45(8):572-81.
2006: Ying Yu; Jinjin Fan; Xin-Sheng Chen; Dairong Wang; Andres J P Klein-Szanto; Robert L Campbell; garret fitzgerald; Colin D Funk
Genetic model of selective COX2 inhibition reveals novel heterodimer signaling.
Nature medicine 2006;12(6):699-704.
2006: Monica Fedele; Vincenzo Fidanza; Sabrina Battista; Francesca Pentimalli; Andres J P Klein-Szanto; Rosa Visone; Ivana De Martino; Antonio Curcio; Carmine Morisco; Luigi Del Vecchio; Gustavo Baldassarre; Claudio Arra; Giuseppe Viglietto; Ciro Indolfi; Carlo M Croce; Alfredo Fusco
Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice.
Cancer research 2006;66(5):2536-43.
2005: Daniel E Bassi; Jian Fu; Ricardo Lopez De Cicco; Andres J P Klein-Szanto
Proprotein convertases: "master switches" in the regulation of tumor growth and progression.
Molecular carcinogenesis 2005;44(3):151-61.
2005: Abdel-Majid Khatib; Daniel E Bassi; Geraldine Siegfried; Andres J P Klein-Szanto; L'Houcine Ouafik
Endo/exo-proteolysis in neoplastic progression and metastasis.
Journal of molecular medicine (Berlin, Germany) 2005;83(11):856-64.
2005: Daniel E Bassi; Ricardo Lopez De Cicco; Jonathan Cenna; Samuel Litwin; Edna Cukierman; Andres J P Klein-Szanto
PACE4 expression in mouse basal keratinocytes results in basement membrane disruption and acceleration of tumor progression.
Cancer research 2005;65(16):7310-9.
2005: Michael D Amatangelo; Daniel E Bassi; Andres J P Klein-Szanto; Edna Cukierman
Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts.
The American journal of pathology 2005;167(2):475-88.
2005: Ricardo López de Cicco; Daniel E Bassi; Stanley Zucker; Nabil G Seidah; Andres J P Klein-Szanto
Human carcinoma cell growth and invasiveness is impaired by the propeptide of the ubiquitous proprotein convertase furin.
Cancer research 2005;65(10):4162-71.
2005: Monica Fedele; Francesca Pentimalli; Gustavo Baldassarre; Sabrina Battista; Andres J P Klein-Szanto; Lawrence Kenyon; Rosa Visone; Ivana De Martino; Andrea Ciarmiello; Claudio Arra; Giuseppe Viglietto; Carlo M Croce; Alfredo Fusco
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.
Oncogene 2005;24(21):3427-35.
2005: Shanchun Guo; Mohamed-Ali Hakimi; David Baillat; Xiaowei Chen; Michele J Farber; Andres J P Klein-Szanto; Neil Cooch; Andrew K Godwin; Ramin Shiekhattar
Linking transcriptional elongation and messenger RNA export to metastatic breast cancers.
Cancer research 2005;65(8):3011-6.
2005: Anatilde M Gonzalez Guerrico; Zahara M Jaffer; Robert E Page; Karl-Heinz Braunewell; Jonathan Chernoff; Andres J P Klein-Szanto
Visinin-like protein-1 is a potent inhibitor of cell adhesion and migration in squamous carcinoma cells.
Oncogene 2005;24(14):2307-16.
2005: Edward R Sauter; Hormoz Ehya; Andres J P Klein-Szanto; Colette Wagner-Mann; Brenda MacGibbon
Fiberoptic ductoscopy findings in women with and without spontaneous nipple discharge.
Cancer 2005;103(5):914-21.
2005: María I Nunez; Daniel G Rosen; John H Ludes-Meyers; Martin Abba; Hyunsuk Kil; Robert Page; Andres J P Klein-Szanto; Andrew K Godwin; Jinsong Liu; Gordon B Mills; C Marcelo Aldaz
WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome.
BMC cancer 2005;5():64.
2005: María I Nunez; John H Ludes-Meyers; Martin Abba; Hyunsuk Kil; Nancy W Abbey; Robert E Page; Aysegul Sahin; Andres J P Klein-Szanto; C Marcelo Aldaz
Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status.
Breast cancer research and treatment 2005;89(2):99-105.
2004: Munenori Takaoka; Hideki Harada; Claudia D Andl; Kenji Oyama; Yoshio Naomoto; Kelly L Dempsey; Andres J P Klein-Szanto; Wafik S El-Deiry; Adda Grimberg; Hiroshi Nakagawa
Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3.
Cancer research 2004;64(21):7711-23.
2004: Gregory P Adams; Calvin Shaller; Ekaterina Dadachova; Heidi H Simmons; Eva M Horak; Abohawariat Tesfaye; Andres J P Klein-Szanto; James D Marks; Martin W Brechbiel; Louis M Weiner
A single treatment of yttrium-90-labeled CHX-A"-C6.5 diabody inhibits the growth of established human tumor xenografts in immunodeficient mice.
Cancer research 2004;64(17):6200-6.
2004: Deborah A Altomare; Hui Qin Wang; Kristine L Skele; Assunta De Rienzo; Andres J P Klein-Szanto; Andrew K Godwin; Joseph R Testa
AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth.
Oncogene 2004;23(34):5853-7.
2004: Ricardo López de Cicco; James C Watson; Daniel E Bassi; Samuel Litwin; Andres J P Klein-Szanto
Simultaneous expression of furin and vascular endothelial growth factor in human oral tongue squamous cell carcinoma progression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(13):4480-8.
2003: Javier Mercapide; Ricardo Lopez De Cicco; Javier S Castresana; Andres J P Klein-Szanto
Stromelysin-1/matrix metalloproteinase-3 (MMP-3) expression accounts for invasive properties of human astrocytoma cell lines.
International journal of cancer. Journal international du cancer 2003;106(5):676-82.
2003: Haleh Mahloogi; Anatilde M González-Guerrico; Ricardo Lopez De Cicco; Daniel E Bassi; Tamra Goodrow; Karl-Heinz Braunewell; Andres J P Klein-Szanto
Overexpression of the calcium sensor visinin-like protein-1 leads to a cAMP-mediated decrease of in vivo and in vitro growth and invasiveness of squamous cell carcinoma cells.
Cancer research 2003;63(16):4997-5004.
2003: Clark M Whitehead; Keith A Earle; John Fetter; Songmei Xu; Theresa Hartman; Daniel C Chan; Tom L M Zhao; Gary Piazza; Andres J P Klein-Szanto; Rifat Pamukcu; Hector Alila; Paul A Bunn; W Joseph Thompson
Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival.
Molecular cancer therapeutics 2003;2(5):479-88.
2003: Sylvia Julien Grille; Alfonso Bellacosa; John Upson; Andres J P Klein-Szanto; Frans van Roy; Whaseon L Kwon; Mark Donowitz; Philip Tsichlis; Lionel Larue
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines.
Cancer research 2003;63(9):2172-8.
2002: Javier Mercapide; Shi Yu Zhang; Xing Fan; Vicente Furió-Bacete; José Schneider; Iñigo López de la Osa; Arthur S Patchefsky; Andres J P Klein-Szanto; Javier S Castresana
CCND1- and ERBB2-gene deregulation and PTEN mutation analyses in invasive lobular carcinoma of the breast.
Molecular carcinogenesis 2002;35(1):6-12.
2002: Shao Chen Liu; Daniel E Bassi; Shi Yu Zhang; Dana Holoran; Claudio J Conti; Andres J P Klein-Szanto
Overexpression of cyclin D2 is associated with increased in vivo invasiveness of human squamous carcinoma cells.
Molecular carcinogenesis 2002;34(3):131-9.
2002: Javier Mercapide; Ricardo Lopez De Cicco; Daniel E Bassi; Javier S Castresana; Gary Thomas; Andres J P Klein-Szanto
Inhibition of furin-mediated processing results in suppression of astrocytoma cell growth and invasiveness.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1740-6.
2002: Monica Fedele; Sabrina Battista; Lawrence Kenyon; Gustavo Baldassarre; Vincenzo Fidanza; Andres J P Klein-Szanto; A F Parlow; Rosa Visone; Giovanna Maria Pierantoni; Eric K Outwater; Massimo Santoro; Carlo M Croce; Alfredo Fusco
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.
Oncogene 2002;21(20):3190-8.
2002: Haleh Mahloogi; Daniel E Bassi; Andres J P Klein-Szanto
Malignant conversion of non-tumorigenic murine skin keratinocytes overexpressing PACE4.
Carcinogenesis 2002;23(4):565-72.
2002: Walter M Klein; Ralph Hruban; Andres J P Klein-Szanto; Robb E Wilentz
Direct correlation between proliferative activity and dysplasia in pancreatic intraepithelial neoplasia (PanIN): additional evidence for a recently proposed model of progression.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2002;15(4):441-7.
2002: Ricardo López de Cicco; Daniel E Bassi; R Page; Andres J P Klein-Szanto
Furin expression in squamous cell carcinomas of the oral cavity and other sites evaluated by tissue microarray technology.
Acta odontológica latinoamericana : AOL 2002;15(1-2):29-37.
2002: Deborah A Altomare; Satoshi Tanno; Assunta De Rienzo; Andres J P Klein-Szanto; Satoshi Tanno; Kristine L Skele; John P Hoffman; Joseph R Testa
Frequent activation of AKT2 kinase in human pancreatic carcinomas.
Journal of cellular biochemistry 2002;87(4):470-6.
2001: Daniel E Bassi; Ricardo Lopez De Cicco; Haleh Mahloogi; S Zucker; Gary Thomas; Andres J P Klein-Szanto
Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10326-31.
2001: Daniel E Bassi; Haleh Mahloogi; L Al-Saleem; Ricardo Lopez De Cicco; J A Ridge; Andres J P Klein-Szanto
Elevated furin expression in aggressive human head and neck tumors and tumor cell lines.
Molecular carcinogenesis 2001;31(4):224-32.
2001: Gustavo Baldassarre; Monica Fedele; Sabrina Battista; Aldo Vecchione; Andres J P Klein-Szanto; Massimo Santoro; Thomas Waldmann; N Azimi; Carlo M Croce; Alfredo Fusco
Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):7970-5.
2001: Gary Piazza; W Joseph Thompson; Rifat Pamukcu; Hector Alila; Clark M Whitehead; Li Liu; John Fetter; W E Gresh; Andres J P Klein-Szanto; D R Farnell; Isao Eto; Clinton J Grubbs
Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis.
Cancer research 2001;61(10):3961-8.
2001: SC Liu; S Y Zhang; J S Babb; J A Ridge; Andres J P Klein-Szanto
Image cytometry of cyclin D1: a prognostic marker for head and neck squamous cell carcinomas.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(5):455-9.
2001: J Virmani; Eric N Johnson; Andres J P Klein-Szanto; Colin D Funk
Role of 'platelet-type' 12-lipoxygenase in skin carcinogenesis.
Cancer letters 2001;162(2):161-5.
2000: Daniel E Bassi; Haleh Mahloogi; Andres J P Klein-Szanto
The proprotein convertases furin and PACE4 play a significant role in tumor progression.
Molecular carcinogenesis 2000;28(2):63-9.
2000: Wendy Bruening; Benoit I Giasson; Andres J P Klein-Szanto; Virginia M-Y Lee; John Q Trojanowski; Andrew K Godwin
Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary.
Cancer 2000;88(9):2154-63.
2000: S Y Zhang; SC Liu; L F Al-Saleem; D Holloran; James Babb; X Guo; Andres J P Klein-Szanto
E2F-1: a proliferative marker of breast neoplasia.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(4):395-401.
2000: SC Liu; Andres J P Klein-Szanto
Markers of proliferation in normal and leukoplakic oral epithelia.
Oral oncology 2000;36(2):145-51.
1999: Edward R Sauter; M Nesbit; Samuel Litwin; Andres J P Klein-Szanto; S Cheffetz; Meenhard Herlyn
Antisense cyclin D1 induces apoptosis and tumor shrinkage in human squamous carcinomas.
Cancer research 1999;59(19):4876-81.
1999: Sabrina Battista; Vincenzo Fidanza; Monica Fedele; Andres J P Klein-Szanto; Eric K Outwater; H Brunner; Massimo Santoro; Carlo M Croce; Alfredo Fusco
The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis.
Cancer research 1999;59(19):4793-7.
1999: Sheila J Miknyoczki; Craig Dionne; Andres J P Klein-Szanto; Bruce Ruggeri
The novel Trk receptor tyrosine kinase inhibitor CEP-701 (KT-5555) exhibits antitumor efficacy against human pancreatic carcinoma (Panc1) xenograft growth and in vivo invasiveness.
Annals of the New York Academy of Sciences 1999;880():252-62.
1999: Sheila J Miknyoczki; D Lang; L Huang; Andres J P Klein-Szanto; Craig Dionne; Bruce Ruggeri
Neurotrophins and Trk receptors in human pancreatic ductal adenocarcinoma: expression patterns and effects on in vitro invasive behavior.
International journal of cancer. Journal international du cancer 1999;81(3):417-27.
1999: S C Liu; Y Hu; Edward R Sauter; Margie L Clapper; S Y Chen; H E Lanfranchi; Paul F Engstrom; Andres J P Klein-Szanto
Image analysis of p53 and cyclin D1 expression in premalignant lesions of the oral mucosa.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1999;21(2):166-73.
1998: Edward R Sauter; Andres J P Klein-Szanto; ES Atillasoy; Kathleen T Montone; Tamra Goodrow; Robert L Binder; John T Seykora; Meenhard Herlyn
Ultraviolet B-induced squamous epithelial and melanocytic cell changes in a xenograft model of cancer development in human skin.
Molecular carcinogenesis 1998;23(3):168-74.
1998: A E Kisielewski; Guang-Hui Xiao; Shao Chen Liu; Andres J P Klein-Szanto; M Novara; J Sina; K Bleicher; Raymond S Yeung; Tamra Goodrow
Analysis of the FHIT gene and its product in squamous cell carcinomas of the head and neck.
Oncogene 1998;17(1):83-91.
1998: SC Liu; Edward R Sauter; Margie L Clapper; R S Feldman; L Levin; S Y Chen; Tim J Yen; Eric A Ross; Paul F Engstrom; Andres J P Klein-Szanto
Markers of cell proliferation in normal epithelia and dysplastic leukoplakias of the oral cavity.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(7):597-603.
1997: Elizabeth Petri Henske; LL Wessner; J Golden; B W Scheithauer; A O Vortmeyer; Z Zhuang; Andres J P Klein-Szanto; D J Kwiatkowski; Raymond S Yeung
Loss of tuberin in both subependymal giant cell astrocytomas and angiomyolipomas supports a two-hit model for the pathogenesis of tuberous sclerosis tumors.
The American journal of pathology 1997;151(6):1639-47.
1997: Guang-Hui Xiao; F Jin; Andres J P Klein-Szanto; Tamra Goodrow; M W Linehan; Raymond S Yeung
The FHIT gene product is highly expressed in the cytoplasm of renal tubular epithelium and is down-regulated in kidney cancers.
The American journal of pathology 1997;151(6):1541-7.
1997: F C Hubbard; Tamra Goodrow; Shao Chen Liu; Murray H Brilliant; P Basset; R E Mains; Andres J P Klein-Szanto
Expression of PACE4 in chemically induced carcinomas is associated with spindle cell tumor conversion and increased invasive ability.
Cancer research 1997;57(23):5226-31.
1997: S Y Zhang; Shao Chen Liu; Tamra Goodrow; R Morris; Andres J P Klein-Szanto
Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms.
Molecular carcinogenesis 1997;18(3):142-52.
1997: Bruce Ruggeri; L Huang; D Berger; H Chang; Andres J P Klein-Szanto; Tamra Goodrow; M Wood; T Obara; C W Heath; H Lynch
Molecular pathology of primary and metastatic ductal pancreatic lesions: analyses of mutations and expression of the p53, mdm-2, and p21/WAF-1 genes in sporadic and familial lesions.
Cancer 1997;79(4):700-16.
1997: S Mitsunaga; Margie L Clapper; S Litwin; P Watts; B Bauer; Andres J P Klein-Szanto
Chemopreventive effect of difluoromethylornithine (DFMO) on mouse skin squamous cell carcinomas induced by benzo(a)pyrene.
Journal of cellular biochemistry. Supplement 1997;28-29():81-9.