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Alison Klein

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Gloria H Lewis; Eileen M O'Reilly; Richard D Schulick; Lauren Ende Schwartz; Huamin Wang; Christopher L Wolfgang; Kenneth H Yu; Frederic B Askin; Andrew M Bellizzi; John L Cameron; Alison P Klein; Ralph H Hruban
Prognosis of minimally invasive carcinoma arising in mucinous cystic neoplasms of the pancreas.
Max Leenders; Donghui Li; Margaret T Mandelson; Robert R McWilliams; Julie B Mendelsohn; Sara H Olson; Alpa V Patel; Gloria Petersen; Kari G Rabe; Elio Riboli; Harvey A Risch; Xiao-Ou Shu; Victoria Stevens; Anne Tjønneland; Geoffrey S Tobias; Dimitrios Trichopoulos; Paolo Vineis; Jarmo Virtamo; Kala Visvanathan; Jean Wactawski-Wende; Brian M Wolpin; Herbert Yu; Kai Yu; Anne Zeleniuch-Jacquotte; Wei Zheng; Ilir Agalliu; Demetrius Albanes; Laufey Amundadottir; Alan A Arslan; Samsiddhi Bhattacharjee; Marie-Christine Boutron-Ruault; Paige M Bracci; H Bas Bueno-de-Mesquita; Julie E Buring; Federico Canzian; Kenneth Chang; STEPHEN CHANOCK; Michelle Cotterchio; Eric J Duell; Joanne W Elena; Charles S Fuchs; Steven Gallinger; J Michael Gaziano; Edward L Giovanucci; Michael Goggins; Myron Gross; Göran Hallmans; Susan E Hankinson; Patricia Hartge; Judith A Hoffman-Bolton; Elizabeth A Holly; Robert N Hoover; David J Hunter; Amy Hutchinson; Eric J Jacobs; Kevin B Jacobs; Mazda Jenab; Kay-Tee Khaw; Alison P Klein; Charles Kooperberg; Peter Kraft; Vittorio Krogh; Robert C Kurtz; Andrea LaCroix; Rachael Z Stolzenberg-Solomon
Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4.
Alison P Klein
Identifying people at a high risk of developing pancreatic cancer.

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All Publications

2013: Gloria H Lewis; Eileen M O'Reilly; Richard D Schulick; Lauren Ende Schwartz; Huamin Wang; Christopher L Wolfgang; Kenneth H Yu; Frederic B Askin; Andrew M Bellizzi; John L Cameron; Alison P Klein; Ralph H Hruban
Prognosis of minimally invasive carcinoma arising in mucinous cystic neoplasms of the pancreas.
The American journal of surgical pathology 2013;37(4):601-5.
2013: Max Leenders; Donghui Li; Margaret T Mandelson; Robert R McWilliams; Julie B Mendelsohn; Sara H Olson; Alpa V Patel; Gloria Petersen; Kari G Rabe; Elio Riboli; Harvey A Risch; Xiao-Ou Shu; Victoria Stevens; Anne Tjønneland; Geoffrey S Tobias; Dimitrios Trichopoulos; Paolo Vineis; Jarmo Virtamo; Kala Visvanathan; Jean Wactawski-Wende; Brian M Wolpin; Herbert Yu; Kai Yu; Anne Zeleniuch-Jacquotte; Wei Zheng; Ilir Agalliu; Demetrius Albanes; Laufey Amundadottir; Alan A Arslan; Samsiddhi Bhattacharjee; Marie-Christine Boutron-Ruault; Paige M Bracci; H Bas Bueno-de-Mesquita; Julie E Buring; Federico Canzian; Kenneth Chang; STEPHEN CHANOCK; Michelle Cotterchio; Eric J Duell; Joanne W Elena; Charles S Fuchs; Steven Gallinger; J Michael Gaziano; Edward L Giovanucci; Michael Goggins; Myron Gross; Göran Hallmans; Susan E Hankinson; Patricia Hartge; Judith A Hoffman-Bolton; Elizabeth A Holly; Robert N Hoover; David J Hunter; Amy Hutchinson; Eric J Jacobs; Kevin B Jacobs; Mazda Jenab; Kay-Tee Khaw; Alison P Klein; Charles Kooperberg; Peter Kraft; Vittorio Krogh; Robert C Kurtz; Andrea LaCroix; Rachael Z Stolzenberg-Solomon
Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4.
Cancer causes & control : CCC 2013;24(3):595-602.
2013: Alison P Klein
Identifying people at a high risk of developing pancreatic cancer.
Nature reviews. Cancer 2013;13(1):66-74.
2012: Shinichi Yachida; Yi Zhong; Jacqueline A Brosnan; JOSEPH HERMAN; Ralph Hruban; Siân Jones; Alison P Klein; Daniel Laheru; Anne M Macgregor-Das; Richard A Morgan; Yoshiki Naito; Tyler Saunders; Victor E Velculescu; Catherine M White; Christopher L Wolfgang; Christine A Iacobuzio-Donahue
Clinical significance of the genetic landscape of pancreatic cancer and implications for identification of potential long-term survivors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(22):6339-47.
2012: Wigdan Al-Sukhni; Melissa Bondy; Ayelet Borgida; Aaron Gropper; Spring Holter; Sarah Joe; Alison P Klein; Anath C Lionel; Christian R Marshall; Sara Moore; Gloria M Petersen; Kari G Rabe; Stephen W Scherer; Ann Grossbart Schwartz; Sapna Syngal; George Zogopoulos; Nora Zwingerman; Steven Gallinger
Identification of germline genomic copy number variation in familial pancreatic cancer.
Human genetics 2012;131(9):1481-94.
2012: Haibo Bai; Mariana F Gayyed; Mehtab Khan; Alison P Klein; Dora M Lam-Himlin; Suresh K Nayar; Duojia Pan; Yang Xu; Pedram Argani; Robert A Anders
Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies.
Human pathology 2012;43(9):1376-85.
2012: Seung-Mo Hong; Ralph Hruban; Mitsuro Kanda; Alison P Klein; Julie Leclerc; Noriyuki Omura; Audrey Vincent; Michael Borges; Marcia Canto; Michael Goggins
Genome-wide somatic copy number alterations in low-grade PanINs and IPMNs from individuals with a family history of pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(16):4303-12.
2012: Chad M McCall; Richard D Schulick; Chanjuan Shi; Christopher L Wolfgang; BARISH EDIL; Trevor A Ellison; Alison P Klein; Günter Klöppel; Björn Konukiewitz; Ralph Hruban
Serotonin expression in pancreatic neuroendocrine tumors correlates with a trabecular histologic pattern and large duct involvement.
Human pathology 2012;43(8):1169-76.
2012: Donghui Li; Margaret T Mandelson; Robert R McWilliams; Julie B Mendelsohn; Sara H Olson; Alpa V Patel; Gloria Petersen; Kari G Rabe; Elio Riboli; Harvey A Risch; Xiao-Ou Shu; Anne Tjønneland; Geoffrey S Tobias; Dimitrios Trichopoulos; Jarmo Virtamo; Kala Visvanathan; Joanne Watters; Bill Wheeler; Brian M Wolpin; Herbert Yu; Kai Yu; Anne Zeleniuch-Jacquotte; Wei Zheng; Ilir Agalliu; Demetrius Albanes; Laufey Amundadottir; Alan A Arslan; Marie-Christine Boutron-Ruault; Paige M Bracci; H Bas Bueno-de-Mesquita; Julie E Buring; Federico Canzian; Kenneth Chang; STEPHEN CHANOCK; Michelle Cotterchio; Xiaoqun Dong; Eric J Duell; Charles S Fuchs; Steven Gallinger; J Michael Gaziano; Edward L Giovannucci; Michael Goggins; Myron Gross; Göran Hallmans; Susan E Hankinson; Patricia Hartge; Judith A Hoffman Bolton; Elizabeth A Holly; Robert N Hoover; David J Hunter; Amy Hutchinson; Eric J Jacobs; Kevin B Jacobs; Mazda Jenab; Li Jiao; Kay-Tee Khaw; Alison P Klein; Charles Kooperberg; Peter Kraft; Vittorio Krogh; Robert C Kurtz; Andrea LaCroix; Rachael Z Stolzenberg-Solomon
Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer.
Carcinogenesis 2012;33(7):1384-90.
2012: Pedro A Pérez-Mancera; Christian Pilarsky; Petra Rümmele; Alistair G Rust; Aaron L Sarver; Kevin A T Silverstein; Shane Stegeman; Derek L Stemple; Jelle J ten Hoeve; Louise van der Weyden; Lodewyk F A Wessels; Stephen A Wood; Jun Yu; David J Adams; Daniela Aust; Andrew V Biankin; Jacqueline A Brosnan; David K Chang; Lara S Collier; Jeroen de Ridder; Michael Goggins; Sean M Grimmond; Robert Grützmann; Colin Herd; Ralph Hruban; Christine A Iacobuzio-Donahue; Ross Kettleborough; Alison P Klein; Spencer Knight; Thomas Knösel; Glen Kristiansen; David A Largaespada; Allen Li; Ang Li; Richard Morgan; David A Tuveson
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
Nature 2012;486(7402):266-70.
2012: Kevin B Jacobs; Mazda Jenab; Li Jiao; Christoffer Johansen; Alison Johnson; Kay-Tee Khaw; Alison P Klein; Manolis Kogevinas; Woon-Puay Koh; Laurence N Kolonel; Charles Kooperberg; Joseph Kovaks; Peter Kraft; Christian P Kratz; Vittorio Krogh; Robert C Kurtz; Andrea LaCroix; Annelie Landgren; Maria Teresa Landi; Loic Le Marchand; Donghui Li; Linda Liao; Jolanta Lissowska; Chenwei Liu; Nuria Malats; Margaret T Mandelson; Gaelle Marenne; Katherine A McGlynn; Roberta McKean-Cowdin; Lorna H McNeill; Robert R McWilliams; Beatrice S Melin; Julie B Mendelsohn; Dominique S Michaud; Lisa Mirabello; Lee E Moore; Sara H Olson; Beata Peplonska; Luis A Pérez-Jurado; Ulrike Peters; Gloria Petersen; Ludmila Prokunina-Olsson; Mark Purdue; You-Lin Qiao; Kari G Rabe; Preetha Rajaraman; Francisco X Real; Elio Riboli; Harvey A Risch; Benjamin Rodriguez-Santiago; Nathaniel Rothman; Melissa Rotunno; Avima Ruder; Benjamin A Rybicki; Joshua Sampson; Sharon A Savage; Fredrick Schumacher; Ann Grossbart Schwartz; Kendra Schwartz; Molly Schwenn; Howard D Sesso; Gianluca Severi; Xiao-Ou Shu; Luis Sierrasesúmaga; Lisa B Signorello; Debra T Silverman; Margaret R Spitz; Victoria L Stevens; Rachael Z Stolzenberg-Solomon; Daniel Stram; Ze-Zhong Tang; Philip R Taylor; Lauren T Teras; Gilles Thomas; Anne Tjønneland; Geoffrey S Tobias; Dimitrios Trichopoulos; Margaret Tucker; Olaya Villa; Jarmo Virtamo; Kala Visvanathan; Sholom Wacholder; Zhaoming Wang; Stephanie J Weinstein; Nicolas Wentzensen; William Wheeler; Emily White; John K Wiencke; Alicja Wolk; Brian M Wolpin; Margaret Wrensch; Xifeng Wu; Jay S Wunder; Yong-Bing Xiang; Meredith Yeager; Herbert Yu; Kai Yu; Jian-Min Yuan; Krista A Zanetti; Anne Zeleniuch-Jacquotte; Wei Zheng; Weiyin Zhou; Regina G Ziegler; Laura E Beane Freeman; Judith A Hoffman Bolton; Ana Patiño García; Nilanjan Chatterjee; Wong-Ho Chow; Charles C Chung; Dario Consonni; Michael B Cook; Michelle Cotterchio; Michael Cullen; Faith G Davis; Michael C Dean; Xiang Deng; Ti Ding; Eric J Duell; Joanne W Elena; Caroline G Epstein; Ralph L Erickson; Jin-Hu Fan; Maria Feychting; Jonine D Figueroa; Joseph F Fraumeni; Neal D Freedman; Charles S Fuchs; Steven Gallinger; Yu-Tang Gao; Susan M Gapstur; Montserrat Garcia-Closas; Mia M Gaudet; J Michael Gaziano; Graham G Giles; Elizabeth M Gillanders; Edward L Giovannucci; Michael Goggins; Lynn Goldin; Alisa M Goldstein; Juan R Gonzalez; Richard G Gorlick; Barry I Graubard; Mark H Greene; Myron D Gross; Christopher A Haiman; Goran Hallmans; Susan E Hankinson; Curtis C Harris; Patricia Hartge; Manal Hassan; Brian E Henderson; Roger Henriksson; Elizabeth A Holly; Robert N Hoover; Marie-Josephe Horner; Ann W Hsing; Nan Hu; David J Hunter; Amy Hutchinson; Peter D Inskip; Christian C Abnet; Anders Ahlbom; Demetrius Albanes; Melinda C Aldrich; Christopher Amos; Laufey Amundadottir; Ulrika Andersson; Irene L Andrulis; Alan A Arslan; Dalsu Baris; Donald A Barkauskas; Christine D Berg; Sonja I Berndt; Pier Alberto Bertazzi; Amanda Black; William J Blot; Cathryn Hufford Bock; Marie-Christine Boutron-Ruault; Paige M Bracci; Louise A Brinton; H Bas Bueno-de-Mesquita; Laurie Burdett; Julie E Buring; Mary A Butler; Federico Canzian; Neil E Caporaso; Tania Carreon; Kenneth Chang; STEPHEN CHANOCK
Detectable clonal mosaicism and its relationship to aging and cancer.
Nature genetics 2012;44(6):651-8.
2012: Marcia Canto; James Farrell; elliot fishman; Joel Fletcher; Michael Goggins; Constance A Griffin; Ralph Hruban; Ihab R Kamel; Alison P Klein; Jeffrey Lee; Daniel Margolis; Koenraad J Mortele; Gloria Petersen; John R Saltzman; Richard D Schulick; Sapna Syngal; Naoki Takahashi; Eric Tamm; Mark Topazian; Raghunandan Vikram; Zhe Zhang; Jennifer E Axilbund; Priya Bhosale
Frequent detection of pancreatic lesions in asymptomatic high-risk individuals.
Gastroenterology 2012;142(4):796-804; quiz e14-5.
2012: Janis M Taube; Suzanne Topalian; Haiying Xu; Geoffrey D Young; Shuming Chen; Alison P Klein; Tracee L McMiller; Drew M Pardoll; Rajni Sharma; Robert A Anders; Lieping Chen
Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape.
Science translational medicine 2012;4(127):127ra37.
2012: Nicholas J Roberts; Richard D Schulick; Ann Grossbart Schwartz; Sapna Syngal; Victor E Velculescu; Bert Vogelstein; Jun Yu; Levy Kopelovich; Nickolas Papadopoulos; Gloria M Petersen; Syed Z Ali; Jennifer E Axilbund; Melissa L Bondy; Michele Cote; James R Eshleman; Steven Gallinger; Michael Goggins; Ralph Hruban; Yuchen Jiao; Kenneth W Kinzler; Alison P Klein
ATM mutations in patients with hereditary pancreatic cancer.
Cancer discovery 2012;2(1):41-6.
2012: Soma Ghosh; Michael Goggins; M Zulfiquer Hossain; Roxann G Ingersoll; Michael Borges; James R Eshleman; Alison P Klein; Scott E Kern
Analysis of polymorphisms and haplotype structure of the human thymidylate synthase genetic region: a tool for pharmacogenetic studies.
PloS one 2012;7(4):e34426.
2012: Alison P Klein
Genetic susceptibility to pancreatic cancer.
Molecular carcinogenesis 2012;51(1):14-24.
2011: Jian Wu; Marcia Canto; James R Eshleman; Michael A Choti; Hannah Carter; G Johan A Offerhaus; Marco Dal Molin; Nickolas Papadopoulos; Laura D Wood; Anirban Maitra; Yuchen Jiao; C Max Schmidt; Kenneth W Kinzler; Rachel Karchin; Volkan Adsay; Alison P Klein; Yoshiki Naito; Michael Goggins; Richard D Schulick; Roeland F de Wilde; Christopher L Wolfgang; David S Klimstra; BARISH EDIL; Luis Alberto Diaz; Levy Kopelovich; Ralph Hruban; Peter J Allen; Bert Vogelstein
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(52):21188-93.
2011: Priya Duggal; Grace Ibay; Alison P Klein
Current gene discovery strategies for ocular conditions.
Investigative ophthalmology & visual science 2011;52(10):7761-70.
2011: Hiroyuki Matsubayashi; Yuji Miyagi; Hiroyuki Ono; Katsuhiko Uesaka; Kentaro Yamazaki; Shuichi Hironaka; Hisatomo Ikehara; Hideyuki Kanemoto; Alison P Klein; Atsuyuki Maeda; Michael Goggins
Risk factors of familial pancreatic cancer in Japan: current smoking and recent onset of diabetes.
Pancreas 2011;40(6):974-8.
2011: Christopher M Heaphy; Sachidanand Hebbar; Ralph Hruban; Yuchen Jiao; Kenneth W Kinzler; Alison P Klein; Anirban Maitra; Suely Kazue Nagahashi Marie; Roger McLendon; Sueli M Oba-Shinjo; G Johan A Offerhaus; Nickolas Papadopoulos; B Ahmed Rasheed; Gregory J Riggins; Fausto J Rodriguez; Chanjuan Shi; Bert Vogelstein; Hai Yan; Chetan Bettegowda; Darell D Bigner; Roeland F de Wilde; Charles G Eberhart; BARISH EDIL; Yiping He; Alan K Meeker
Altered telomeres in tumors with ATRX and DAXX mutations.
Science (New York, N.Y.) 2011;333(6041):425.
2011: Jian Wu; Christopher L Wolfgang; Laura D Wood; Peter J Allen; Marcia Canto; Marco Dal Molin; Luis Alberto Diaz; BARISH EDIL; James R Eshleman; Michael Goggins; Ralph Hruban; Kenneth W Kinzler; Alison P Klein; Anirban Maitra; Hanno Matthaei; Nickolas Papadopoulos; C Max Schmidt; Richard D Schulick; Bert Vogelstein
Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development.
Science translational medicine 2011;3(92):92ra66.
2011: Alison P Klein; Joan E Bailey-Wilson; Ching-Yu Cheng; Priya Duggal; Ronald Klein; Kristine E Lee; Barbara E K Klein
Linkage analysis of quantitative refraction and refractive errors in the Beaver Dam Eye Study.
Investigative ophthalmology & visual science 2011;52(8):5220-5.
2011: Andrew Jaffe; Audrey Chu; Priya Duggal; Asieh Golozar; Ankit Maroo; Genevieve Wojcik; Alison P Klein
Identification of functional genetic variation in exome sequence analysis.
BMC proceedings 2011;5 Suppl 9():S13.
2011: Maria C Villarroel; N V Rajeshkumar; Ignacio Garrido-Laguna; Ana De Jesus-Acosta; Siân Jones; Anirban Maitra; Ralph Hruban; James R Eshleman; Alison P Klein; Daniel Laheru; Ross C Donehower; Manuel Hidalgo
Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer.
Molecular cancer therapeutics 2011;10(1):3-8.
2010: Gloria M Petersen; Laufey Amundadottir; Charles S Fuchs; Peter Kraft; Rachael Z Stolzenberg-Solomon; Kevin B Jacobs; Alan A Arslan; H Bas Bueno-de-Mesquita; Steven Gallinger; Myron Gross; Kathy Helzlsouer; Elizabeth A Holly; Eric J Jacobs; Alison P Klein; Andrea LaCroix; Donghui Li; Margaret T Mandelson; Sara H Olson; Harvey A Risch; Wei Zheng; Demetrius Albanes; William R Bamlet; Christine D Berg; Marie-Christine Boutron-Ruault; Julie E Buring; Paige M Bracci; Federico Canzian; SANDRA CLIPP; Michelle Cotterchio; Mariza de Andrade; Eric J Duell; J Michael Gaziano; Edward L Giovannucci; Michael Goggins; Göran Hallmans; Susan E Hankinson; Manal Hassan; Barbara Howard; David J Hunter; Amy Hutchinson; Mazda Jenab; Rudolf Kaaks; Charles Kooperberg; Vittorio Krogh; Robert C Kurtz; Shannon M Lynch; Robert R McWilliams; Julie B Mendelsohn; Dominique S Michaud; Hemang Parikh; Alpa V Patel; Petra Peeters; Aleksandar Rajkovic; Elio Riboli; Laudina Rodriguez; Daniela Seminara; Xiao-Ou Shu; Gilles Thomas; Anne Tjønneland; Geoffrey S Tobias; Dimitrios Trichopoulos; Stephen K Van Den Eeden; Jarmo Virtamo; Jean Wactawski-Wende; Zhaoming Wang; Brian M Wolpin; Herbert Yu; Kai Yu; Anne Zeleniuch-Jacquotte; Joseph F Fraumeni; Robert N Hoover; Patricia Hartge; STEPHEN CHANOCK
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.
Nature genetics 2010;42(3):224-8.
2010: Kieran A Brune; Bryan Lau; Emily Palmisano; Marcia Canto; Michael Goggins; Ralph Hruban; Alison P Klein
Importance of age of onset in pancreatic cancer kindreds.
Journal of the National Cancer Institute 2010;102(2):119-26.
2010: Ralph Hruban; Marcia Canto; Michael Goggins; Richard D Schulick; Alison P Klein
Update on familial pancreatic cancer.
Advances in surgery 2010;44():293-311.
2010: Anne Marie Lennon; Alison P Klein; Michael Goggins
ABO blood group and other genetic variants associated with pancreatic cancer.
Genome medicine 2010;2(6):39.
2009: Li Wang; Kieran A Brune; Kala Visvanathan; Daniel Laheru; JOSEPH HERMAN; Christopher L Wolfgang; Richard D Schulick; John L Cameron; Michael Goggins; Ralph Hruban; Alison P Klein
Elevated cancer mortality in the relatives of patients with pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(11):2829-34.
2009: Kim Walter; Seung-Mo Hong; Sinead Nyhan; Marcia Canto; Neal S Fedarko; Alison P Klein; Margaret Griffith; Noriyuki Omura; Susan M Medghalchi; Francis P Kuhajda; Michael Goggins
Serum fatty acid synthase as a marker of pancreatic neoplasia.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(9):2380-5.
2009: Laufey Amundadottir; Peter Kraft; Rachael Z Stolzenberg-Solomon; Charles S Fuchs; Gloria M Petersen; Alan A Arslan; H Bas Bueno-de-Mesquita; Myron Gross; Kathy Helzlsouer; Eric J Jacobs; Andrea LaCroix; Wei Zheng; Demetrius Albanes; William Bamlet; Christine D Berg; Franco Berrino; Sheila Bingham; Julie E Buring; Paige M Bracci; Federico Canzian; Françoise Clavel-Chapelon; SANDRA CLIPP; Michelle Cotterchio; Mariza de Andrade; Eric J Duell; John W Fox; Steven Gallinger; J Michael Gaziano; Edward L Giovannucci; Michael Goggins; Carlos A González; Göran Hallmans; Susan E Hankinson; Manal Hassan; Elizabeth A Holly; David J Hunter; Amy Hutchinson; Rebecca Jackson; Kevin B Jacobs; Mazda Jenab; Rudolf Kaaks; Alison P Klein; Charles Kooperberg; Robert C Kurtz; Donghui Li; Shannon M Lynch; Margaret Mandelson; Robert R McWilliams; Julie B Mendelsohn; Dominique S Michaud; Sara H Olson; Kim Overvad; Alpa V Patel; Petra Peeters; Aleksandar Rajkovic; Elio Riboli; Harvey A Risch; Xiao-Ou Shu; Gilles Thomas; Geoffrey S Tobias; Dimitrios Trichopoulos; Stephen K Van Den Eeden; Jarmo Virtamo; Jean Wactawski-Wende; Brian M Wolpin; Herbert Yu; Kai Yu; Anne Zeleniuch-Jacquotte; STEPHEN CHANOCK; Patricia Hartge; Robert N Hoover
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.
Nature genetics 2009;41(9):986-90.
2009: Amanda Blackford; Oscar K Serrano; Christopher L Wolfgang; Giovanni Parmigiani; Siân Jones; Xiaosong Zhang; DONALD PARSONS; Jimmy Cheng-Ho Lin; Rebecca J Leary; James R Eshleman; Michael Goggins; Elizabeth M Jaffee; Christine A Iacobuzio-Donahue; Anirban Maitra; John L Cameron; Kelly Olino; Richard D Schulick; Jordan Winter; JOSEPH HERMAN; Daniel Laheru; Alison P Klein; Bert Vogelstein; Kenneth W Kinzler; Victor E Velculescu; Ralph Hruban
SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(14):4674-9.
2009: Gyungah Jun; Hong Guo; Barbara E K Klein; Ronald Klein; Jie Jin Wang; Paul Mitchell; Hui Miao; Kristine E Lee; Tripti Joshi; Matthias Buck; Preeti Chugha; David Bardenstein; Alison P Klein; Joan E Bailey-Wilson; Xiaohua Gong; Tim D Spector; Toby Andrew; Christopher J Hammond; Robert C Elston; Sudha K Iyengar; Bingcheng Wang
EPHA2 is associated with age-related cortical cataract in mice and humans.
PLoS genetics 2009;5(7):e1000584.
2009: Alison P Klein; Bhoom Suktitipat; Priya Duggal; Kristine E Lee; Ronald Klein; Joan E Bailey-Wilson; Barbara E K Klein
Heritability analysis of spherical equivalent, axial length, corneal curvature, and anterior chamber depth in the Beaver Dam Eye Study.
Archives of ophthalmology 2009;127(5):649-55.
2009: Amanda Blackford; Giovanni Parmigiani; Thomas W Kensler; Christopher L Wolfgang; Siân Jones; Xiaosong Zhang; DONALD PARSONS; Jimmy Cheng-Ho Lin; Rebecca J Leary; James R Eshleman; Michael Goggins; Elizabeth M Jaffee; Christine A Iacobuzio-Donahue; Anirban Maitra; Alison P Klein; John L Cameron; Kelly Olino; Richard D Schulick; Jordan Winter; Bert Vogelstein; Victor E Velculescu; Kenneth W Kinzler; Ralph Hruban
Genetic mutations associated with cigarette smoking in pancreatic cancer.
Cancer research 2009;69(8):3681-8.
2009: Christine A Iacobuzio-Donahue; BAOJIN FU; Shinichi Yachida; Mingde Luo; Hisashi Abe; Clark M Henderson; Felip Vilardell; Zheng Wang; Jesse W Keller; Priya Banerjee; JOSEPH HERMAN; John L Cameron; Charles J Yeo; Marc K Halushka; James R Eshleman; Marian Raben; Alison P Klein; Ralph Hruban; Manuel Hidalgo; Daniel Laheru
DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(11):1806-13.
2009: Siân Jones; Ralph Hruban; Mihoko Kamiyama; Michael Borges; Xiaosong Zhang; DONALD PARSONS; Jimmy Cheng-Ho Lin; Emily Palmisano; Kieran Brune; Elizabeth M Jaffee; Christine A Iacobuzio-Donahue; Anirban Maitra; Giovanni Parmigiani; Scott E Kern; Victor E Velculescu; Kenneth W Kinzler; Bert Vogelstein; James R Eshleman; Michael Goggins; Alison P Klein
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.
Science (New York, N.Y.) 2009;324(5924):217.
2009: Alison P Klein; Michael Borges; Margaret Griffith; Kieran Brune; Seung-Mo Hong; Noriyuki Omura; Ralph Hruban; Michael Goggins
Absence of deleterious palladin mutations in patients with familial pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(4):1328-30.
2009: Chanjuan Shi; Ralph Hruban; Alison P Klein
Familial pancreatic cancer.
Archives of pathology & laboratory medicine 2009;133(3):365-74.
2009: Yoonhee Kim; Robert Wojciechowski; Heejong Sung; Rasika A Mathias; Li Wang; Alison P Klein; Rhoshel K Lenroot; James D Malley; Joan E Bailey-Wilson
Evaluation of random forests performance for genome-wide association studies in the presence of interaction effects.
BMC proceedings 2009;3 Suppl 7():S64.
2009: Jennifer E Axilbund; Pedram Argani; Mihoko Kamiyama; Emily Palmisano; Marian Raben; Michael Borges; Kieran A Brune; Michael Goggins; Ralph Hruban; Alison P Klein
Absence of germline BRCA1 mutations in familial pancreatic cancer patients.
Cancer biology & therapy 2009;8(2):131-5.
2008: Kieran Brune; Seung-Mo Hong; Ang Li; Shinichi Yachida; Tadayoshi Abe; Margaret Griffith; Dawei Yang; Noriyuki Omura; James R Eshleman; Marcia Canto; Richard D Schulick; Alison P Klein; Ralph Hruban; Christine Iacobuzio-Donohue; Michael Goggins
Genetic and epigenetic alterations of familial pancreatic cancers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(12):3536-42.
2008: Angela A Steinhardt; Mariana F Gayyed; Alison P Klein; Jixin Dong; Anirban Maitra; Duojia Pan; Elizabeth Montgomery; Robert A Anders
Expression of Yes-associated protein in common solid tumors.
Human pathology 2008;39(11):1582-9.
2008: Siân Jones; Xiaosong Zhang; DONALD PARSONS; Jimmy Cheng-Ho Lin; Rebecca J Leary; Philipp Angenendt; Parminder Mankoo; Hannah Carter; Hirohiko Kamiyama; Antonio Jimeno; Seung-Mo Hong; BAOJIN FU; Ming-Tseh Lin; Eric S Calhoun; Mihoko Kamiyama; Kimberly Walter; Tatiana Nikolskaya; Yuri Nikolsky; James Hartigan; Douglas R Smith; Manuel Hidalgo; Steven D Leach; Alison P Klein; Elizabeth M Jaffee; Michael Goggins; Anirban Maitra; Christine A Iacobuzio-Donahue; James R Eshleman; Scott E Kern; Ralph Hruban; Rachel Karchin; Nickolas Papadopoulos; Giovanni Parmigiani; Bert Vogelstein; Victor E Velculescu; Kenneth W Kinzler
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.
Science (New York, N.Y.) 2008;321(5897):1801-6.
2008: Thomas A Laffan; Karen M Horton; Alison P Klein; Bruce Berlanstein; Stanley S Siegelman; Satomi Kawamoto; Pamela T Johnson; elliot fishman; Ralph Hruban
Prevalence of unsuspected pancreatic cysts on MDCT.
AJR. American journal of roentgenology 2008;191(3):802-7.
2008: Amy Berrington de Gonzalez; Ji Eun Yun; Sang-Yi Lee; Alison P Klein; Sun Ha Jee
Pancreatic cancer and factors associated with the insulin resistance syndrome in the Korean cancer prevention study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(2):359-64.
2008: Yu Chuan Tai; Sining Chen; Giovanni Parmigiani; Alison P Klein
Incorporating tumor immunohistochemical markers in BRCA1 and BRCA2 carrier prediction.
Breast cancer research : BCR 2008;10(2):401.
2008: Aik Choon Tan; Jian-Bing Fan; Collins Karikari; Marina Bibikova; Eliza Wickham Garcia; Lixin Zhou; David Barker; david serre; Georg Feldmann; Ralph Hruban; Alison P Klein; Michael Goggins; Fergus J. Couch; Thomas J Hudson; Raimond L Winslow; Anirban Maitra; Aravinda Chakravarti
Allele-specific expression in the germline of patients with familial pancreatic cancer: an unbiased approach to cancer gene discovery.
Cancer biology & therapy 2008;7(1):135-44.
2007: Priya Duggal; Alison P Klein; Kristine E Lee; Ronald Klein; Barbara E K Klein; Joan E Bailey-Wilson
The GLC1H glaucoma locus may reflect glaucoma with elevated intraocular pressure.
Archives of ophthalmology 2007;125(12):1716-7; author reply 1717.
2007: Ralph Hruban; Alison P Klein; James R Eshleman; Jennifer E Axilbund; Michael Goggins
Familial pancreatic cancer: from genes to improved patient care.
Expert review of gastroenterology & hepatology 2007;1(1):81-8.
2007: Hiroyuki Matsubayashi; Jeffrey R Infante; Jordan Winter; Alison P Klein; Richard D Schulick; Ralph Hruban; Kala Visvanathan; Michael Goggins
Tumor COX-2 expression and prognosis of patients with resectable pancreatic cancer.
Cancer biology & therapy 2007;6(10):1569-75.
2007: Robert Lucito; Shubha Suresh; Kimberly Walter; Akhilesh Pandey; B Lakshmi; Alexander Krasnitz; Jonathan Sebat; Michael Wigler; Alison P Klein; Kieran Brune; Emily Palmisano; Anirban Maitra; Michael Goggins; Ralph Hruban
Copy-number variants in patients with a strong family history of pancreatic cancer.
Cancer biology & therapy 2007;6(10):1592-9.
2007: Wenyi Wang; Sining Chen; Kieran Brune; Ralph Hruban; Giovanni Parmigiani; Alison P Klein
PancPRO: risk assessment for individuals with a family history of pancreatic cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(11):1417-22.
2007: Safia N Salaria; PETER ILLEI; Rajni Sharma; Kimberly M Walter; Alison P Klein; James R Eshleman; Anirban Maitra; Richard D Schulick; Jordan Winter; Michel M Ouellette; Michael Goggins; Ralph Hruban
Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells.
Cancer biology & therapy 2007;6(3):324-8.
2007: Alison P Klein; Mariza de Andrade; Ralph Hruban; Melissa Bondy; Ann Grossbart Schwartz; Steven Gallinger; Henry T Lynch; Sapna Syngal; Kari G Rabe; Michael Goggins; Gloria M Petersen
Linkage analysis of chromosome 4 in families with familial pancreatic cancer.
Cancer biology & therapy 2007;6(3):320-3.
2007: Fergus J. Couch; Michele R Johnson; Kari G Rabe; Kieran Brune; Mariza de Andrade; Michael Goggins; Heidi Rothenmund; Steven Gallinger; Alison P Klein; Gloria M Petersen; Ralph Hruban
The prevalence of BRCA2 mutations in familial pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(2):342-6.
2007: Jeffrey R Infante; Hiroyuki Matsubayashi; Norihiro Sato; James Tonascia; Alison P Klein; Taylor A Riall; Charles Yeo; Christine A Iacobuzio-Donahue; Michael Goggins
Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(3):319-25.
2007: Alison P Klein; Priya Duggal; Kristine E Lee; Ronald Klein; Joan E Bailey-Wilson; Barbara E K Klein
Confirmation of linkage to ocular refraction on chromosome 22q and identification of a novel linkage region on 1q.
Archives of ophthalmology 2007;125(1):80-5.
2007: Priya Duggal; Alison P Klein; Kristine E Lee; Ronald Klein; Barbara E K Klein; Joan E Bailey-Wilson
Identification of novel genetic loci for intraocular pressure: a genomewide scan of the Beaver Dam Eye Study.
Archives of ophthalmology 2007;125(1):74-9.
2006: Kieran Brune; Tadayoshi Abe; Marcia Canto; Lauren O'Malley; Alison P Klein; Anirban Maitra; N Volkan Adsay; elliot fishman; John L Cameron; Charles J Yeo; Scott E Kern; Michael Goggins; Ralph Hruban
Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer.
The American journal of surgical pathology 2006;30(9):1067-76.
2006: Valeria Sebastiani; Francesca Ricci; Belen Rubio-Viqueira; Belen Rubio-Viquiera; Piotr Kulesza; Charles J Yeo; Manuel Hidalgo; Alison P Klein; Daniel Laheru; Christine A Iacobuzio-Donahue
Immunohistochemical and genetic evaluation of deoxycytidine kinase in pancreatic cancer: relationship to molecular mechanisms of gemcitabine resistance and survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(8):2492-7.
2006: Gloria M Petersen; Mariza de Andrade; Michael Goggins; Ralph Hruban; Melissa Bondy; Jeannette F Korczak; Steven Gallinger; Henry T Lynch; Sapna Syngal; Kari G Rabe; Daniela Seminara; Alison P Klein
Pancreatic cancer genetic epidemiology consortium.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(4):704-10.
2006: Hiroyuki Matsubayashi; Marcia Canto; Norihiro Sato; Alison P Klein; Tadayoshi Abe; Keishi Yamashita; Charles J Yeo; Anthony N Kalloo; Ralph Hruban; Michael Goggins
DNA methylation alterations in the pancreatic juice of patients with suspected pancreatic disease.
Cancer research 2006;66(2):1208-17.
2006: Ralph Hruban; N Volkan Adsay; Jorge Albores-Saavedra; Miriam R Anver; Andrew V Biankin; Gregory P Boivin; Emma E Furth; Toru Furukawa; Alison P Klein; David S Klimstra; Gunter Kloppel; Gregory Y Lauwers; Daniel S Longnecker; Jutta Luttges; Anirban Maitra; G Johan A Offerhaus; Lucía Pérez-Gallego; Mark Redston; David A Tuveson
Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.
Cancer research 2006;66(1):95-106.
2005: Ralph Hruban; Marcia Canto; Constance A Griffin; Scott E Kern; Alison P Klein; Daniel Laheru; Charles J Yeo
Treatment of familial pancreatic cancer and its precursors.
Current treatment options in gastroenterology 2005;8(5):365-75.
2005: Alison P Klein; Priya Duggal; Kristine E Lee; Jennifer A O'Neill; Ronald Klein; Joan E Bailey-Wilson; Barbara E K Klein
Polygenic effects and cigarette smoking account for a portion of the familial aggregation of nuclear sclerosis.
American journal of epidemiology 2005;161(8):707-13.
2005: Priya Duggal; Alison P Klein; Kristine E Lee; Sudha K Iyengar; Ronald Klein; Joan E Bailey-Wilson; Barbara E K Klein
A genetic contribution to intraocular pressure: the beaver dam eye study.
Investigative ophthalmology & visual science 2005;46(2):555-60.
2005: Alison P Klein; Priya Duggal; Kristine E Lee; Ronald Klein; Joan E Bailey-Wilson; Barbara E K Klein
Support for polygenic influences on ocular refractive error.
Investigative ophthalmology & visual science 2005;46(2):442-6.
2005: Priya Duggal; Elizabeth M Gillanders; Rasika A Mathias; Grace P Ibay; Alison P Klein; Agnes B Baffoe-Bonnie; Liang Ou; Ian P Dusenberry; Ya-Yu Tsai; Peter S Chines; Betty Q Doan; Joan E Bailey-Wilson
Identification of tag single-nucleotide polymorphisms in regions with varying linkage disequilibrium.
BMC genetics 2005;6 Suppl 1():S73.
2005: Alison P Klein; Ya-Yu Tsai; Priya Duggal; Elizabeth M Gillanders; Michael Barnhart; Rasika A Mathias; Ian P Dusenberry; Amy Turiff; Peter S Chines; Janet Goldstein; Robert Wojciechowski; Wayne Hening; Elizabeth W Pugh; Joan E Bailey-Wilson
Investigation of altering single-nucleotide polymorphism density on the power to detect trait loci and frequency of false positive in nonparametric linkage analyses of qualitative traits.
BMC genetics 2005;6 Suppl 1():S20.
2005: Alison P Klein
Overview of linkage analysis: application to pancreatic cancer.
Methods in molecular medicine 2005;103():329-41.
2004: Elizabeth M Gillanders; Anthony Masiello; Derek Gildea; Lowell Umayam; Priya Duggal; Mary Pat Jones; Alison P Klein; Diana Freas-Lutz; Grace Ibay; Kenneth L Trout; Tyra G Wolfsberg; Jeffrey M. Trent; Joan E Bailey-Wilson; Andreas D Baxevanis
GeneLink: a database to facilitate genetic studies of complex traits.
BMC genomics 2004;5():81.
2004: Sara Chandros Hull; Holly Gooding; Alison P Klein; Esther Warshauer-Baker; Susan Metosky; Benjamin S Wilfond
Genetic research involving human biological materials: a need to tailor current consent forms.
IRB 2004;26(3):1-7.
2004: Alison P Klein; Kieran Brune; Gloria M Petersen; Michael Goggins; Anne C Tersmette; G Johan A Offerhaus; Constance A Griffin; John L Cameron; Charles J Yeo; Scott E Kern; Ralph Hruban
Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds.
Cancer research 2004;64(7):2634-8.
2003: Alison P Klein; Ilija Kovac; Alexa J M Sorant; Agnes B Baffoe-Bonnie; Betty Q Doan; Grace Ibay; Erica Lockwood; Diptasri Mandal; Lekshmi Santhosh; Karen Weissbecker; Jessica Woo; April Zambelli-Weiner; JIE ZHANG; Daniel Q Naiman; James D Malley; Joan E Bailey-Wilson
Importance sampling method of correction for multiple testing in affected sib-pair linkage analysis.
BMC genetics 2003;4 Suppl 1():S73.
2002: Alison P Klein; Terri H beaty; Joan E Bailey-Wilson; Kieran Brune; Ralph Hruban; Gloria M Petersen
Evidence for a major gene influencing risk of pancreatic cancer.
Genetic epidemiology 2002;23(2):133-49.
2001: Alison P Klein; Ralph Hruban; Kieran Brune; Gloria M Petersen; Michael Goggins
Familial pancreatic cancer.
Cancer journal (Sudbury, Mass.) 2001;7(4):266-73.
2001: Yen-Feng Chiu; Anjene Addington; Terri H beaty; Alison P Klein; Kung-Yee Liang
Multipoint linkage analysis under heterogeneity: incorporation of parametric and nonparametric approaches.
Genetic epidemiology 2001;21 Suppl 1():S55-60.
2001: Peter P Zandi; Alison P Klein; Anjene Addington; J B Hetmanski; L Roberts; R Peila; Sadeep Shrestha; C K Shaw; hosen kiat; C D Langefeld; Terri H beaty
Multilocus linkage analysis of the German asthma data.
Genetic epidemiology 2001;21 Suppl 1():S210-5.
1999: Diptasri Mandal; Alexa J M Sorant; Elizabeth W Pugh; S E Marcus; Alison P Klein; Rasika A Mathias; Jennifer O'Neill; L F Temiyakarn; Alexander F Wilson; Joan E Bailey-Wilson
Environmental covariates: effects on the power of sib-pair linkage methods.
Genetic epidemiology 1999;17 Suppl 1():S643-8.
1999: Suh-Hang Hank Juo; Elizabeth W Pugh; Agnes B Baffoe-Bonnie; A Kingman; Alexa J M Sorant; Alison P Klein; Jennifer O'Neill; Rasika A Mathias; Alexander F Wilson; Joan E Bailey-Wilson
Possible linkage of alcoholism, monoamine oxidase activity and P300 amplitude to markers on chromosome 12q24.
Genetic epidemiology 1999;17 Suppl 1():S193-8.