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Christine Klein

Research Profile

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Ana Westenberger; Aloysius Domingo; Dirk Dressler; Karen Freimann; Gabriele Gillessen-Kaesbach; Uta Gölnitz; Sascha Heinitz; Roland D Jamora; Lilian V Lee; Katja Lohmann; Inga Nagel; Arlene R Ng; Arndt Rolfs; Raymond L Rosales; Reiner Siebert; Uwe Walter; Christine Klein
X-linked Dystonia-Parkinsonism manifesting in a female patient due to atypical turner syndrome.
Nikola Kresojević; Milan B Lakočević; Milija Mijajlović; Ivana Novaković; Aleksandra Pavlović; Stojan Perić; Marina Svetel; Valerija Dobričić; Milena Janković; Christine Klein; Vladimir S Kostić
Transcranial sonography in patients with Parkinson's disease with glucocerebrosidase mutations.
Anne Weissbach; Norbert Brüggemann; Anne Grünewald; Meike Kasten; Christine Klein; Peter Trillenberg; Johann Hagenah
Prominent psychiatric comorbidity in the dominantly inherited movement disorder myoclonus-dystonia.

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All Publications

2013: Ana Westenberger; Aloysius Domingo; Dirk Dressler; Karen Freimann; Gabriele Gillessen-Kaesbach; Uta Gölnitz; Sascha Heinitz; Roland D Jamora; Lilian V Lee; Katja Lohmann; Inga Nagel; Arlene R Ng; Arndt Rolfs; Raymond L Rosales; Reiner Siebert; Uwe Walter; Christine Klein
X-linked Dystonia-Parkinsonism manifesting in a female patient due to atypical turner syndrome.
Movement disorders : official journal of the Movement Disorder Society 2013;28(5):675-8.
2013: Nikola Kresojević; Milan B Lakočević; Milija Mijajlović; Ivana Novaković; Aleksandra Pavlović; Stojan Perić; Marina Svetel; Valerija Dobričić; Milena Janković; Christine Klein; Vladimir S Kostić
Transcranial sonography in patients with Parkinson's disease with glucocerebrosidase mutations.
Parkinsonism & related disorders 2013;19(4):431-5.
2013: Anne Weissbach; Norbert Brüggemann; Anne Grünewald; Meike Kasten; Christine Klein; Peter Trillenberg; Johann Hagenah
Prominent psychiatric comorbidity in the dominantly inherited movement disorder myoclonus-dystonia.
Parkinsonism & related disorders 2013;19(4):422-5.
2013: Christine Klein; T Gasser
[Introduction to neurogenetics].
Der Nervenarzt 2013;84(2):135-6.
2013: Meike Kasten; Alexander Katalinic; Julia Graf; Johann Hagenah; Anne Lorwin; Elke Peters; Heiner Raspe; Eva-Juliane Vollstedt; Christine Klein
Cohort Profile: a population-based cohort to study non-motor symptoms in parkinsonism (EPIPARK).
International journal of epidemiology 2013;42(1):128-128k.
2013: K R Kumar; K Lohmann; C M Sue; J R Mazzulli; A Ramirez; A Rolfs; Marina Svetel; Christine Klein; V Kostic; Dimitri Krainc; N Kresojević; R N Alcalay; A Göbel; Anne Grünewald
Glucocerebrosidase mutations in a Serbian Parkinson's disease population.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2013;20(2):402-5.
2013: Aleksandar Rakovic; Philip Seibler; Katharina Shurkewitsch; Alessandra Zanon; Anne Grünewald; Johann Hagenah; Dimitri Krainc; Christine Klein
Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons.
The Journal of biological chemistry 2013;288(4):2223-37.
2013: Christine Klein; Alexander Münchau
Progressive dystonia.
Handbook of clinical neurology 2013;113():1889-97.
2012: Ina Schmitt; Jan Pierre van Rooyen; Alexander Volk; Ullrich Wüllner; Julian Becker; Tim Becker; Hassan Khazneh; Christine Klein; Vladimir S Kostic; Christian Kubisch; Alfredo Ramirez
Variants in the 3'UTR of SNCA do not affect miRNA-433 binding and alpha-synuclein expression.
European journal of human genetics : EJHG 2012;20(12):1265-9.
2012: Anne Weissbach; Norbert Brüggemann; Johann Hagenah; Meike Kasten; Christine Klein; Ebba Lohmann; Thora Lohnau; Hiltrud Muhle; Irene Pichler; Peter P Pramstaller; Alexander Schmidt; Eberhard Schwinger; Katharina Siegesmund; Ulrich Stephani; Katja Lohmann
Exome sequencing in a family with restless legs syndrome.
Movement disorders : official journal of the Movement Disorder Society 2012;27(13):1686-9.
2012: Anna Göbel; Christine Klein; Katja Lohmann; Eric A Macklin; Rebecca A Betensky; Susen Winkler; David K Simon
Genetic risk factors in Parkinson's disease: single gene effects and interactions of genotypes.
Journal of neurology 2012;259(11):2503-5.
2012: Christine Klein; Inke R König; Katja Lohmann
Exome sequencing for gene discovery: time to set standard criteria.
Annals of neurology 2012;72(4):627-8.
2012: Susanne A Schneider; Laura Drude; Meike Kasten; Christine Klein; Johann Hagenah
A study of subtle motor signs in early Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2012;27(12):1563-6.
2012: Kishore R Kumar; Johann Hagenah; Marcus Heldmann; Meike Kasten; Christine Klein; Vladimir S Kostić; Thomas F Münte; Alfredo Ramirez; Juan Segura-Aguilar; David K Simon; Carolyn M Sue; Marina Svetel; Sinem Tunc; Peter Vieregge; Anne Weissbach; Katja Lohmann
Frequency of the D620N mutation in VPS35 in Parkinson disease.
Archives of neurology 2012;69(10):1360-4.
2012: Silke Appenzeller; Daniela Berg; Günther Deuschl; Thomas Gasser; Johann Hagenah; Meike Kasten; Christine Klein; Frank Papengut; Stefan Schreiber; Karin Srulijes; Sandra Thier; Gregor Kuhlenbäumer
No association between NOD2 variants and Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2012;27(9):1191-2.
2012: Anne Grünewald; Björn Arns; Alexander Münchau; Aleksandar Rakovic; Alfredo Ramirez; Philip Seibler; Carolyn M Sue; Christine Klein
ATP13A2 mutations impair mitochondrial function in fibroblasts from patients with Kufor-Rakeb syndrome.
Neurobiology of aging 2012;33(8):1843.e1-7.
2012: N Brüggemann; Johann Hagenah; P Bauer; W Külper; K Lohmann; Thora Lohnau; Cristian Pattaro; Peter P Pramstaller; Olaf Riess; A Rolfs; R Siebert; Andreas Sprenger; V Tadic; H Tönnies; Peter Vieregge; Susen Winkler; Christine Klein
Autosomal dominant Parkinson's disease in a large German pedigree.
Acta neurologica Scandinavica 2012;126(2):129-37.
2012: Katja Lohmann; Christine Klein
Familial idiopathic basal ganglia calcification: unraveling the first genetic cause.
Movement disorders : official journal of the Movement Disorder Society 2012;27(8):963.
2012: Alexander Schmidt; Karin Wiegers; Eckart Altenmüller; Hans-Christian Jabusch; Christine Klein; André Lee; Katja Lohmann
The GAG deletion in Tor1A (DYT1) is a rare cause of complex musician's dystonia.
Parkinsonism & related disorders 2012;18(5):690-1.
2012: Simone Zittel; A Ramirez; Hartwig R Siebner; J P M van der Vegt; Tobias Bäumer; M I Behrens; N Brüggemann; Christian Gerloff; Christine Klein; J Kroeger; Alexander Münchau
Motor pathway excitability in ATP13A2 mutation carriers: a transcranial magnetic stimulation study.
Parkinsonism & related disorders 2012;18(5):590-4.
2012: Alexander Schmidt; Carolyn M Sue; Hans-Jürgen Christen; Anne Grünewald; Johann Hagenah; Hans Hartmann; Kishore R Kumar; Matthias Leben; Katja Lohmann; Alexander Münchau; Katharina Redyk; Christine Klein
Two faces of the same coin: benign familial infantile seizures and paroxysmal kinesigenic dyskinesia caused by PRRT2 mutations.
Archives of neurology 2012;69(5):668-70.
2012: Meike Kasten; Lena Kertelge; Norbert Brüggemann; Carsten Buhmann; Johann Hagenah; Kishore R Kumar; Rebekka Lencer; Katja Lohmann; Alexander Schmidt; Hartwig Siebner; Vera Tadic; Joyce van der Vegt; Christine Klein
Depression and quality of life in monogenic compared to idiopathic, early-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2012;27(6):754-9.
2012: Silke Anders; Christine Klein; Thomas Münte; Anna Pohl; Peter Pramstaller; Benjamin Sack; Ferdinand Binkofski
Compensatory premotor activity during affective face processing in subclinical carriers of a single mutant Parkin allele.
Brain : a journal of neurology 2012;135(Pt 4):1128-40.
2012: Julia Richter; Steffen Paschen; Ole Ammerpohl; Silke Appenzeller; Norbert Brüggemann; Günther Deuschl; Christine Klein; Gregor Kuhlenbäumer
No evidence for differential methylation of α-synuclein in leukocyte DNA of Parkinson's disease patients.
Movement disorders : official journal of the Movement Disorder Society 2012;27(4):590-1.
2012: Christine Klein; Dimitri Krainc
Movement disorders in 2011: Translating new research findings into clinical practice.
Nature reviews. Neurology 2012;8(2):65-6.
2012: Nils Freundlieb; Christian Gerloff; Christine Klein; Stephan Philipp; Susanne A Schneider; Norbert Brüggemann; Friedhelm C Hummel
No association of the BDNF val66met polymorphism with implicit associative vocabulary and motor learning.
PloS one 2012;7(11):e48327.
2012: Christine Klein; Ana Westenberger
Genetics of Parkinson's disease.
Cold Spring Harbor perspectives in medicine 2012;2(1):a008888.
2011: Susanne A Schneider; Uwe H Schneider; Christine Klein
Genetic testing for neurologic disorders.
Seminars in neurology 2011;31(5):542-52.
2011: Christine Klein
Next-generation neurogenetics: the future has begun.
Seminars in neurology 2011;31(5):431-2.
2011: Sascha Heinitz; Christine Klein; Ana Djarmati
The p.S77N presenilin-associated rhomboid-like protein mutation is not a frequent cause of early-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2011;26(13):2441-2.
2011: Simone Zittel; Tobias Bäumer; Norbert Brüggemann; Christian Gerloff; Christine Klein; Alexander Münchau
Paroxysmal cervical myoclonus.
Movement disorders : official journal of the Movement Disorder Society 2011;26(13):2445-6.
2011: Beenish Arif; Nobert Brüggemann; Amara Fatima; Anne Grünewald; Christine Klein; Katja Lohmann; Akbar Malik; Alfredo Ramirez; Arndt Rolfs; Jens Würfel; Arif Ali; Sadaf Naz
An unusual neurological syndrome of crawling gait, dystonia, pyramidal signs, and limited speech.
Movement disorders : official journal of the Movement Disorder Society 2011;26(12):2279-83.
2011: Christoph Kamm; Christine Klein; Friedrich Asmus; Reiner Benecke; Thomas Gasser; Johann Hagenah; Alexander Münchau; Jens Pahnke; Christoph Schrader; Nils Uflacker; Jens Volkmann; Matthias Wittstock; Alexander Wolters; Katja Lohmann
No evidence for THAP1/DYT6 variants as disease modifiers in DYT1 dystonia.
Movement disorders : official journal of the Movement Disorder Society 2011;26(11):2136-7.
2011: Vladimir S Kostić; Maja Krajinović; Milica Lukić-Ječmenica; Ivana Novaković; Lela Brajković; Valerija Dobričić; Christine Klein; Aleksandra Pavlović
Exclusion of linkage to chromosomes 14q, 2q37 and 8p21.1-q11.23 in a Serbian family with idiopathic basal ganglia calcification.
Journal of neurology 2011;258(9):1637-42.
2011: Christine Klein; B Landwehrmeyer; T Münte; Johann Hagenah; T Klockgether
[The presymptomatic stage of neurodegenerative disorders].
Der Nervenarzt 2011;82(8):994-1001.
2011: Susanne A Schneider; Christine Klein
What is the role of genetic testing in movement disorders practice?
Current neurology and neuroscience reports 2011;11(4):351-61.
2011: N Brüggemann; J Wuerfel; D Petersen; Christine Klein; J Hagenah; Susanne A Schneider
Idiopathic NBIA--clinical spectrum and transcranial sonography findings.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2011;18(6):e58-9.
2011: Susanne Steinlechner; Gabriele Schmid; Vera Sobottka; Birte Behn; Alexander Benthien; Norbert Brüggemann; Christine Klein; Rebekka Lencer
Restless legs syndrome as a possible predictor for psychiatric disorders in parents of children with ADHD.
European archives of psychiatry and clinical neuroscience 2011;261(4):285-91.
2011: Philip Seibler; John Graziotto; Hyun Jeong; Filip Simunovic; Christine Klein; Dimitri Krainc
Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(16):5970-6.
2011: Susanne A Schneider; Alfredo Ramirez; Kaveh Shafiee; Frank J Kaiser; Alev Erogullari; Norbert Brüggemann; Susen Winkler; Ideh Bahman; Alma Osmanovic; Mohammad A Shafa; KP Bhatia; Hossein Najmabadi; Christine Klein; Katja Lohmann
Homozygous THAP1 mutations as cause of early-onset generalized dystonia.
Movement disorders : official journal of the Movement Disorder Society 2011;26(5):858-61.
2011: Norbert Brüggemann; Johann Hagenah; Kaili Stanley; Christine Klein; Cuiling Wang; Deborah Raymond; Laurie Ozelius; Susan Bressman; Rachel Saunders-Pullman
Substantia nigra hyperechogenicity with LRRK2 G2019S mutations.
Movement disorders : official journal of the Movement Disorder Society 2011;26(5):885-8.
2011: Meike Kasten; Norbert Brüggemann; Inke R König; Katja Doerry; Susanne Steinlechner; Liv Wenzel; Katja Lohmann; Christine Klein; Rebekka Lencer
Risk for antipsychotic-induced extrapyramidal symptoms: influence of family history and genetic susceptibility.
Psychopharmacology 2011;214(3):729-36.
2011: Johann Hagenah; Inke R König; Charlotte Kötter; Günter Seidel; Christine Klein; Norbert Brüggemann
Basal ganglia hyperechogenicity does not distinguish between patients with primary dystonia and healthy individuals.
Journal of neurology 2011;258(4):590-5.
2011: Maurizio Facheris; Andrew A Hicks; Cosetta Minelli; Johann M Hagenah; Vladimir Kostic; Susan Campbell; Caroline Hayward; Claudia B Volpato; Cristian Pattaro; Veronique Vitart; Alan Wright; Harry Campbell; Christine Klein; Peter P Pramstaller
Variation in the uric acid transporter gene SLC2A9 and its association with AAO of Parkinson's disease.
Journal of molecular neuroscience : MN 2011;43(3):246-50.
2011: Christine Klein; Andreas Ziegler
From GWAS to clinical utility in Parkinson's disease.
Lancet 2011;377(9766):613-4.
2011: Alexander Schmidt; Hans-Christian Jabusch; Eckart Altenmüller; Leonie Enders; Rachel Saunders-Pullman; Susan Bressman; Alexander Münchau; Christine Klein; Johann Hagenah
Phenotypic spectrum of musician's dystonia: a task-specific disorder?
Movement disorders : official journal of the Movement Disorder Society 2011;26(3):546-9.
2011: Leonie Enders; June T Spector; Eckart Altenmüller; Alexander Schmidt; Christine Klein; Hans-Christian Jabusch
Musician's dystonia and comorbid anxiety: two sides of one coin?
Movement disorders : official journal of the Movement Disorder Society 2011;26(3):539-42.
2011: Andrey Yurevich Abramov; Matthew E Gegg; Anne Grunewald; Christine Klein; Nicholas William Wood; Anthony Henry Vernon Schapira
Bioenergetic consequences of PINK1 mutations in Parkinson disease.
PloS one 2011;6(10):e25622.
2011: Aleksandar Rakovic; Anne Grünewald; Lisa Voges; Sarah Hofmann; Slobodanka Orolicki; Katja Lohmann; Christine Klein
PINK1-Interacting Proteins: Proteomic Analysis of Overexpressed PINK1.
Parkinson's disease 2011;2011():153979.
2011: Aleksandar Rakovic; Anne Grünewald; Jan Kottwitz; Norbert Brüggemann; Peter P Pramstaller; Katja Lohmann; Christine Klein
Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts.
PloS one 2011;6(3):e16746.
2010: Björn Machner; Andreas Sprenger; Maria Isabel Behrens; Alfredo Ramirez; Norbert Brüggemann; Christine Klein; Christoph Helmchen
Eye movement disorders in ATP13A2 mutation carriers (PARK9).
Movement disorders : official journal of the Movement Disorder Society 2010;25(15):2687-9.
2010: Norbert Brüggemann; Susanne A Schneider; Thurid Sander; Christine Klein; Johann Hagenah
Distinct basal ganglia hyperechogenicity in idiopathic basal ganglia calcification.
Movement disorders : official journal of the Movement Disorder Society 2010;25(15):2661-4.
2010: Lena Kertelge; Norbert Brüggemann; Alexander Schmidt; Vera Tadic; Claudia Wisse; Sylwia Dankert; Laura Drude; Joyce van der Vegt; Hartwig Siebner; Heike Pawlack; Peter P Pramstaller; Maria Isabel Behrens; Alfredo Ramirez; Dirk Reichel; Carsten Buhmann; Johann Hagenah; Christine Klein; Katja Lohmann; Meike Kasten
Impaired sense of smell and color discrimination in monogenic and idiopathic Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2010;25(15):2665-9.
2010: Norbert Brüggemann; Johann Hagenah; Kathrin Reetz; Alexander Schmidt; Meike Kasten; Inga Buchmann; Susanne Eckerle; M Bähre; Alexander Münchau; Ana Djarmati; Joyce van der Vegt; Hartwig Siebner; Ferdinand Binkofski; Alfredo Ramirez; Maria I Behrens; Christine Klein
Recessively inherited parkinsonism: effect of ATP13A2 mutations on the clinical and neuroimaging phenotype.
Archives of neurology 2010;67(11):1357-63.
2010: Simone Zittel; Christian K E Moll; Norbert Brüggemann; Vera Tadic; Wolfgang Hamel; Meike Kasten; Katja Lohmann; Thora Lohnau; Susen Winkler; Christian Gerloff; Rainer Schönweiler; Johann Hagenah; Christine Klein; Alexander Münchau; Susanne A Schneider
Clinical neuroimaging and electrophysiological assessment of three DYT6 dystonia families.
Movement disorders : official journal of the Movement Disorder Society 2010;25(14):2405-12.
2010: Frank J Kaiser; Alma Osmanoric; Aleksandar Rakovic; Alev Erogullari; Nils Uflacker; Diana Braunholz; Thora Lohnau; Slobodanka Orolicki; Melanie Albrecht; Gabriele Gillessen-Kaesbach; Christine Klein; Katja Lohmann
The dystonia gene DYT1 is repressed by the transcription factor THAP1 (DYT6).
Annals of neurology 2010;68(4):554-9.
2010: N Brüggemann; J Vegt; Christine Klein; Hartwig R Siebner
[Imaging of genetic aspects of Parkinson's disease].
Der Nervenarzt 2010;81(10):1196-203.
2010: Stephan Klebe; Sandra Thier; Delia Lorenz; Michael Nothnagel; Stefan Schreiber; Christine Klein; Johann Hagenah; Meike Kasten; Daniela Berg; Karin Srulijes; Thomas Gasser; Günther Deuschl; Gregor Kuhlenbäumer
LINGO1 is not associated with Parkinson's disease in German patients.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(6):1173-8.
2010: Anne Weissbach; Ana Djarmati; Christine Klein; Natasa Dragasević; Christine Zühlke; Aleksandar Raković; Miodrag Guzvić; Elisabeth Butz; Holger Tönnies; Reiner Siebert; Igor Petrović; Marina Svetel; Vladimir S Kostić; Katja Lohmann
Possible genetic heterogeneity of spinocerebellar ataxia linked to chromosome 15.
Movement disorders : official journal of the Movement Disorder Society 2010;25(11):1577-82.
2010: Rachel Saunders-Pullman; Johann Hagenah; Vijay Dhawan; Kaili Stanley; Gregory Pastores; Swati Sathe; Michele Tagliati; Kelly Condefer; Christina Palmese; Norbert Brüggemann; Christine Klein; Anne Marie Andersen Roe; Ruth Kornreich; Laurie J Ozelius; Susan Bressman
Gaucher disease ascertained through a Parkinson's center: imaging and clinical characterization.
Movement disorders : official journal of the Movement Disorder Society 2010;25(10):1364-72.
2010: Georg Kägi; Christine Klein; Nicholas W Wood; Susanne A Schneider; Peter P Pramstaller; Vera Tadic; Niall Quinn; Bart P C van de Warrenburg; Kailash P Bhatia
Nonmotor symptoms in Parkin gene-related parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2010;25(9):1279-84.
2010: B Machner; Christine Klein; Andreas Sprenger; P Baumbach; Peter P Pramstaller; Christoph Helmchen; Wolfgang Heide
Eye movement disorders are different in Parkin-linked and idiopathic early-onset PD.
Neurology 2010;75(2):125-8.
2010: A Schmidt; Christine Klein
The role of genes in causing dystonia.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2010;17 Suppl 1():65-70.
2010: Thilo van Eimeren; Ferdinand Binkofski; Carsten Buhmann; Johann Hagenah; Antonio P Strafella; Peter P Pramstaller; Hartwig R Siebner; Christine Klein
Imaging movement-related activity in medicated Parkin-associated and sporadic Parkinson's disease.
Parkinsonism & related disorders 2010;16(6):384-7.
2010: Sebastian Paus; F Gadow; O Kaut; Michael Knapp; Christine Klein; Thomas Klockgether; Ullrich Wüllner
Tremor in Parkinson's disease is not associated with the DRD3 Ser9Gly polymorphism.
Parkinsonism & related disorders 2010;16(6):381-3.
2010: Rachel Saunders-Pullman; Kaili Stanley; Norbert Brüggemann; Deborah Raymond; Marta San Luciano; Cuiling Wang; Christine Klein; Naomi Lubarr; Laurie Ozelius; Susan Bressman; Johann Hagenah
Substantia nigra hyperechogenicity in DYT6 dystonia: a pilot study.
Parkinsonism & related disorders 2010;16(6):420-2.
2010: Meike Kasten; Lena Kertelge; Norbert Brüggemann; Joyce van der Vegt; Alexander Schmidt; Vera Tadic; Carsten Buhmann; Susanne Steinlechner; Maria Isabel Behrens; Alfredo Ramirez; Ferdinand Binkofski; Hartwig Siebner; Heiner Raspe; Johann Hagenah; Rebekka Lencer; Christine Klein
Nonmotor symptoms in genetic Parkinson disease.
Archives of neurology 2010;67(6):670-6.
2010: C Eggers; A Schmidt; Johann Hagenah; N Brüggemann; J C Klein; V Tadic; L Kertelge; M Kasten; Ferdinand Binkofski; Hartwig R Siebner; B Neumaier; G R Fink; Rüdiger Hilker; Christine Klein
Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficit.
Neurology 2010;74(22):1798-805.
2010: Johann Hagenah; Inke R König; Jürgen Sperner; Lucas Wessel; Günter Seidel; Kelly Condefer; Rachel Saunders-Pullman; Christine Klein; Norbert Brüggemann
Life-long increase of substantia nigra hyperechogenicity in transcranial sonography.
NeuroImage 2010;51(1):28-32.
2010: Norbert Brüggemann; Christine Klein
Genetics of primary torsion dystonia.
Current neurology and neuroscience reports 2010;10(3):199-206.
2010: M Walter; Michael Bonin; Rachel Saunders-Pullman; E M Valente; M Loi; M Gambarin; D Raymond; M Tinazzi; Christoph Kamm; N Glöckle; Sven Poths; Thomas Gasser; Susan Bressman; Christine Klein; L J Ozelius; Olaf Riess; Kathrin Grundmann
Expression profiling in peripheral blood reveals signature for penetrance in DYT1 dystonia.
Neurobiology of disease 2010;38(2):192-200.
2010: Connie Marras; Christine Klein; Anthony E Lang; Yosuke Wakutani; Danielle Moreno; Christine Sato; Edwin Yip; Renato P Munhoz; Katja Lohmann; Ana Djarmati; Andrew Bi; Ekaterina Rogaeva
LRRK2 and Parkin mutations in a family with parkinsonism-Lack of genotype-phenotype correlation.
Neurobiology of aging 2010;31(4):721-2.
2010: Kaili Stanley; Johann Hagenah; Norbert Brüggemann; Kathrin Reetz; Lawrence Severt; Christine Klein; Qiping Yu; Carol A Derby; Seth Pullman; Rachel Saunders-Pullman
Digitized spiral analysis is a promising early motor marker for Parkinson Disease.
Parkinsonism & related disorders 2010;16(3):233-4.
2010: Irene Pichler; Fabio Marroni; Cristian Pattaro; Katja Lohmann; Alessandro De Grandi; Christine Klein; Andrew A Hicks; Peter P Pramstaller
Parkin gene modifies the effect of RLS4 on the age at onset of restless legs syndrome (RLS).
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(1):350-5.
2010: Anne Grünewald; Lisa Voges; Aleksandar Rakovic; Meike Kasten; Himesha Vandebona; Claudia Hemmelmann; Katja Lohmann; Slobodanka Orolicki; Alfredo Ramirez; Anthony H V Schapira; Peter P Pramstaller; Carolyn M Sue; Christine Klein
Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts.
PloS one 2010;5(9):e12962.
2010: Susanne Steinlechner; Christine Klein; Andreas Moser; Rebekka Lencer; Johann Hagenah
Botulinum toxin B as an effective and safe treatment for neuroleptic-induced sialorrhea.
Psychopharmacology 2010;207(4):593-7.
2010: Rolf Verleger; Johann Hagenah; Manuel Weiss; Thomas Ewers; I Heberlein; Peter P Pramstaller; Hartwig R Siebner; Christine Klein
Responsiveness to distracting stimuli, though increased in Parkinson's disease, is decreased in asymptomatic PINK1 and Parkin mutation carriers.
Neuropsychologia 2010;48(2):467-76.
2009: J P M van der Vegt; B F L van Nuenen; Bastiaan R Bloem; Christine Klein; Hartwig R Siebner
Imaging the impact of genes on Parkinson's disease.
Neuroscience 2009;164(1):191-204.
2009: Christine Klein; Giorgio Rovelli; Wolfdieter Springer; Christoph Schall; Thomas Gasser; Philipp J Kahle
Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment.
Journal of neurochemistry 2009;111(3):703-15.
2009: Christine Klein; Susanne A Schneider; Anthony E Lang
Hereditary parkinsonism: Parkinson disease look-alikes--an algorithm for clinicians to "PARK" genes and beyond.
Movement disorders : official journal of the Movement Disorder Society 2009;24(14):2042-58.
2009: Ana Djarmati; Johann Hagenah; Kathrin Reetz; Susen Winkler; Maria Isabel Behrens; Heike Pawlack; Katja Lohmann; Alfredo Ramirez; Vera Tadić; Norbert Brüggemann; Daniela Berg; Hartwig R Siebner; Anthony E Lang; Peter P Pramstaller; Ferdinand Binkofski; Vladimir S Kostić; Jens Volkmann; Thomas Gasser; Christine Klein
ATP13A2 variants in early-onset Parkinson's disease patients and controls.
Movement disorders : official journal of the Movement Disorder Society 2009;24(14):2104-11.
2009: Rebekka Lencer; Susanne Steinlechner; J Stahlberg; H Rehling; M Orth; T Baeumer; Hans-Jürgen Rumpf; Christian Meyer; Christine Klein; A Muenchau; Johann Hagenah
Primary focal dystonia: evidence for distinct neuropsychiatric and personality profiles.
Journal of neurology, neurosurgery, and psychiatry 2009;80(10):1176-9.
2009: Anne Grünewald; M E Gegg; J-W Taanman; R H King; Norman Kock; Christine Klein; Anthony H V Schapira
Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology.
Experimental neurology 2009;219(1):266-73.
2009: Susanne Hertel; Andreas Sprenger; Christine Klein; Detlef Kömpf; Christoph Helmchen; Hubert Kimmig
Different saccadic abnormalities in PINK1 mutation carriers and in patients with non-genetic Parkinson's disease.
Journal of neurology 2009;256(7):1192-4.
2009: Norbert Brüggemann; Manfred Mitterer; Andrea J Lanthaler; Ana Djarmati; Johann Hagenah; Karin Wiegers; Susen Winkler; Heike Pawlack; Thora Lohnau; Peter P Pramstaller; Christine Klein; Katja Lohmann
Frequency of heterozygous Parkin mutations in healthy subjects: need for careful prospective follow-up examination of mutation carriers.
Parkinsonism & related disorders 2009;15(6):425-9.
2009: Sebastian Paus; Franziska Gadow; Michael Knapp; Christine Klein; Thomas Klockgether; Ullrich Wüllner
Motor complications in patients form the German Competence Network on Parkinson's disease and the DRD3 Ser9Gly polymorphism.
Movement disorders : official journal of the Movement Disorder Society 2009;24(7):1080-4.
2009: J Gierthmühlen; F Lienau; R Maag; J M Hagenah; Günther Deuschl; E Fritzer; Christine Klein; Ralf Baron; C Helmchen
Somatosensory processing in a German family with PINK1 mutations: its potential role in Parkinson disease.
Journal of neurology, neurosurgery, and psychiatry 2009;80(5):571-4.
2009: Ana Djarmati; Susanne A Schneider; Katja Lohmann; Susen Winkler; Heike Pawlack; Johann Hagenah; Norbert Brüggemann; Simone Zittel; Tania Fuchs; Aleksandar Raković; Alexander Schmidt; Hans-Christian Jabusch; Robert Wilcox; Vladimir S Kostić; Hartwig R Siebner; Eckart Altenmüller; Alexander Münchau; Laurie J Ozelius; Christine Klein
Mutations in THAP1 (DYT6) and generalised dystonia with prominent spasmodic dysphonia: a genetic screening study.
Lancet neurology 2009;8(5):447-52.
2009: N Brüggemann; Norman Kock; K Lohmann; Inke R König; A Rakovic; Johann Hagenah; A Schmidt; Andreas Ziegler; Hans-Christian Jabusch; Hartwig R Siebner; Eckart Altenmüller; Alexander Münchau; Christine Klein
The D216H variant in the DYT1 gene: a susceptibility factor for dystonia in familial cases?
Neurology 2009;72(16):1441-3.
2009: A Schmidt; Hans-Christian Jabusch; Eckart Altenmüller; Johann Hagenah; N Brüggemann; K Lohmann; L Enders; Patricia L Kramer; Rachel Saunders-Pullman; Susan Bressman; Alexander Münchau; Christine Klein
Etiology of musician's dystonia: familial or environmental?
Neurology 2009;72(14):1248-54.
2009: Bart van Nuenen; M M Weiss; Bastiaan R Bloem; K Reetz; Thilo van Eimeren; K Lohmann; J Hagenah; P P Pramstaller; F Binkofski; Christine Klein; Hartwig R Siebner
Heterozygous carriers of a Parkin or PINK1 mutation share a common functional endophenotype.
Neurology 2009;72(12):1041-7.
2009: Aleksandar Rakovic; Barbara Stiller; Ana Djarmati; Antonia Flaquer; Jan Freudenberg; Mohammad-Reza Toliat; Michael Linnebank; Vladimir Kostic; Katja Lohmann; Sebastian Paus; Peter Nürnberg; Christian Kubisch; Christine Klein; Ullrich Wüllner; Alfredo Ramirez
Genetic association study of the P-type ATPase ATP13A2 in late-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2009;24(3):429-33.
2009: Kathrin Reetz; Christian Gaser; Christine Klein; Johann Hagenah; Christian Büchel; Stefan Gottschalk; Peter P Pramstaller; Hartwig R Siebner; Ferdinand Binkofski
Structural findings in the basal ganglia in genetically determined and idiopathic Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2009;24(1):99-103.
2009: Christine Klein; Katja Lohmann
Parkinson disease(s): is "Parkin disease" a distinct clinical entity?
Neurology 2009;72(2):106-7.
2009: Bart F L van Nuenen; Thilo van Eimeren; Joyce P M van der Vegt; Carsten Buhmann; Christine Klein; Bastiaan R Bloem; Hartwig R Siebner
Mapping preclinical compensation in Parkinson's disease: an imaging genomics approach.
Movement disorders : official journal of the Movement Disorder Society 2009;24 Suppl 2():S703-10.
2009: Katja Zschiedrich; Inke R König; Norbert Brüggemann; Norman Kock; Meike Kasten; Klaus L Leenders; Vladimir Kostić; Peter Vieregge; Andreas Ziegler; Christine Klein; Katja Lohmann
MDR1 variants and risk of Parkinson disease. Association with pesticide exposure?
Journal of neurology 2009;256(1):115-20.
2008: N Brueggemann; P Odin; A Gruenewald; V Tadic; J Hagenah; Günter Seidel; K Lohmann; Christine Klein; A Djarmati
Re: Alpha-synuclein gene duplication is present in sporadic Parkinson disease.
Neurology 2008;71(16):1294; author reply 1294.
2008: Emilie Guettard; Marie France Portnoi; Katja Lohmann-Hedrich; Boris Keren; Sylvie Rossignol; Susen Winkler; Imen El Kamel; Smaranda Leu; Emmanuelle Apartis; Marie Vidailhet; Christine Klein; Emmanuel Roze
Myoclonus-dystonia due to maternal uniparental disomy.
Archives of neurology 2008;65(10):1380-5.
2008: A Schmidt; S A Schneider; Johann Hagenah; Christine Klein
[Dystonia].
Der Nervenarzt 2008;79 Suppl 2():53-63; quiz 64-5.
2008: Johann Hagenah; B Becker; N Brüggemann; Ana Djarmati; K Lohmann; Andreas Sprenger; Christine Klein; Günter Seidel
Transcranial sonography findings in a large family with homozygous and heterozygous PINK1 mutations.
Journal of neurology, neurosurgery, and psychiatry 2008;79(9):1071-4.
2008: Christopher F McNicoll; Jeanne C Latourelle; Marcy E MacDonald; Mark F Lew; Oksana Suchowersky; Christine Klein; Lawrence I Golbe; Margery H Mark; John H Growdon; G Frederick Wooten; Ray L Watts; Mark Guttman; Brad A Racette; Joel S Perlmutter; Anwar Ahmed; Holly A Shill; Carlos Singer; Marie H Saint-Hilaire; Tiffany Massood; Karen W Huskey; Anita L DeStefano; Tammy Gillis; Jayalakshmi Mysore; Stefano Goldwurm; Gianni Pezzoli; Kenneth B Baker; Ilia Itin; Irene Litvan; Garth Nicholson; Alastair Corbett; Martha Nance; Edward Drasby; Stuart Isaacson; David J Burn; Patrick F Chinnery; Peter P Pramstaller; Jomana Al-Hinti; Anette T Moller; Karen Ostergaard; Scott J Sherman; Richard Roxburgh; Barry Snow; John T Slevin; Franca Cambi; James Gusella; Richard H Myers
Huntington CAG repeat size does not modify onset age in familial Parkinson's disease: the GenePD study.
Movement disorders : official journal of the Movement Disorder Society 2008;23(11):1596-601.
2008: Anita L DeStefano; Jeanne Latourelle; Mark F Lew; Oksana Suchowersky; Christine Klein; Lawrence I Golbe; Margery H Mark; John H Growdon; G Fredrick Wooten; Ray L Watts; Mark Guttman; Brad A Racette; Joel S Perlmutter; Lynn Marlor; Holly A Shill; Carlos Singer; Stefano Goldwurm; Gianni Pezzoli; Marie H Saint-Hilaire; Audrey E Hendricks; Adam Gower; Sally Williamson; Michael W Nagle; Jemma B Wilk; Tiffany Massood; Karen W Huskey; Kenneth B Baker; Ilia Itin; Irene Litvan; Garth Nicholson; Alastair Corbett; Martha Nance; Edward Drasby; Stuart Isaacson; David J Burn; Patrick F Chinnery; Peter P Pramstaller; Jomana Al-Hinti; Anette T Moller; Karen Ostergaard; Scott J Sherman; Richard Roxburgh; Barry Snow; John T Slevin; Franca Cambi; James Gusella; Richard H Myers
Replication of association between ELAVL4 and Parkinson disease: the GenePD study.
Human genetics 2008;124(1):95-9.
2008: Maurizio Francesco Facheris; Susanna Maniak; Francesco Scaravilli; Birgitt Schuele; Christine Klein; Peter Paul Pramstaller
Pure akinesia as initial presentation of PSP: a clinicopathological study.
Parkinsonism & related disorders 2008;14(6):517-9.
2008: Kathrin Reetz; Rebekka Lencer; Susanne Steinlechner; Christian Gaser; Johann Hagenah; Christian Büchel; Dirk Petersen; Norman Kock; Ana Djarmati; Hartwig R Siebner; Christine Klein; Ferdinand Binkofski
Limbic and frontal cortical degeneration is associated with psychiatric symptoms in PINK1 mutation carriers.
Biological psychiatry 2008;64(3):241-7.
2008: Daniel G Healy; Mario Falchi; Sean S O'Sullivan; Vincenzo Bonifati; Alexandra Durr; Susan Bressman; Alexis Brice; Jan Aasly; Cyrus Zabetian; Stefano Goldwurm; Joaquim Ferreira; Eduardo Tolosa; Denise M Kay; Christine Klein; David R Williams; Connie Marras; Anthony E Lang; Zbigniew K Wszolek; Jose Berciano; Anthony H V Schapira; Timothy Lynch; Kailash P Bhatia; Thomas Gasser; Andrew J Lees; Nicholas W Wood
Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study.
Lancet neurology 2008;7(7):583-90.
2008: J E Tobin; J C Latourelle; M F Lew; Christine Klein; O Suchowersky; H A Shill; Lawrence I Golbe; M H Mark; John H Growdon; G F Wooten; B A Racette; J S Perlmutter; Ray L Watts; M Guttman; K B Baker; S Goldwurm; G Pezzoli; Carlos Singer; M H Saint-Hilaire; A E Hendricks; S Williamson; M W Nagle; J B Wilk; T Massood; J M Laramie; A L DeStefano; I Litvan; G Nicholson; A Corbett; S Isaacson; David J Burn; P F Chinnery; P P Pramstaller; S Sherman; J Al-hinti; E Drasby; M Nance; A T Moller; K Ostergaard; R Roxburgh; B Snow; J T Slevin; F Cambi; James Gusella; Richard H Myers
Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study.
Neurology 2008;71(1):28-34.
2008: Hiltrud Muhle; Anja Neumann; Katja Lohmann-Hedrich; Thora Lohnau; Yang Lu; Susen Winkler; Stephan Waltz; Anke Fischenbeck; Patricia L Kramer; Christine Klein; Ulrich Stephani
Childhood-onset restless legs syndrome: clinical and genetic features of 22 families.
Movement disorders : official journal of the Movement Disorder Society 2008;23(8):1113-21; quiz 1203.
2008: Christoph Kamm; H Fischer; B Garavaglia; S Kullmann; Manu Sharma; C Schrader; Kathrin Grundmann; Christine Klein; I Borggraefe; E Lobsien; Andreas Kupsch; N Nardocci; Thomas Gasser
Susceptibility to DYT1 dystonia in European patients is modified by the D216H polymorphism.
Neurology 2008;70(23):2261-2.
2008: Philip Seibler; Ana Djarmati; Brigitte Langpap; Johann Hagenah; Alexander Schmidt; Norbert Brüggemann; Hartwig R Siebner; Hans-Christian Jabusch; Eckart Altenmüller; Alexander Münchau; Katja Lohmann; Christine Klein
A heterozygous frameshift mutation in PRKRA (DYT16) associated with generalised dystonia in a German patient.
Lancet neurology 2008;7(5):380-1.
2008: K Haugarvoll; R Rademakers; Jennifer Kachergus; K Nuytemans; O A Ross; J M Gibson; E-K Tan; C Gaig; E Tolosa; S Goldwurm; M Guidi; Giulio Riboldazzi; L Brown; U Walter; R Benecke; Daniela Berg; T Gasser; J Theuns; P Pals; Patrick cras; P Paul De Deyn; S Engelborghs; B Pickut; Ryan Uitti; T Foroud; W C Nichols; J Hagenah; Christine Klein; Amir Samii; Cyrus Zabetian; Vincenzo Bonifati; Christine Van Broeckhoven; Matthew J Farrer; Zbigniew K Wszolek
Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease.
Neurology 2008;70(16 Pt 2):1456-60.
2008: Christine Klein; Andreas Ziegler
How to predict the risk of Parkinson disease in relatives of parkin mutation carriers: a complex puzzle of age, penetrance, and number of mutated alleles.
Archives of neurology 2008;65(4):443-4.
2008: Elena Moro; Jens Volkmann; I R König; S Winkler; A Hiller; S Hassin-Baer; J Herzog; Alfons Schnitzler; K Lohmann; Marcus Pinsker; J Voges; A Djarmatic; P Seibler; Andres M Lozano; Ekaterina Rogaeva; Anthony E Lang; Günther Deuschl; Christine Klein
Bilateral subthalamic stimulation in Parkin and PINK1 parkinsonism.
Neurology 2008;70(14):1186-91.
2008: Deborah Raymond; Rachel Saunders-Pullman; Patricia de Carvalho Aguiar; Birgitt Schule; Norman Kock; Jennifer Friedman; Juliette Harris; Blair Ford; Steven Frucht; Gary A Heiman; Danna Jennings; Dana Doheny; Mitchell F Brin; Deborah de Leon Brin; Trisha Multhaupt-Buell; Anthony E Lang; Roger Kurlan; Christine Klein; Laurie J Ozelius; Susan Bressman
Phenotypic spectrum and sex effects in eleven myoclonus-dystonia families with epsilon-sarcoglycan mutations.
Movement disorders : official journal of the Movement Disorder Society 2008;23(4):588-92.
2008: Sebastian Paus; Anne Grünewald; Christine Klein; Michael Knapp; Alexander Zimprich; Bernd Janetzky; J Carsten Möller; Thomas Klockgether; Ullrich Wüllner
The DRD2 TaqIA polymorphism and demand of dopaminergic medication in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2008;23(4):599-602.
2008: Christine Klein
DYT16: a new twist to familial dystonia.
Lancet neurology 2008;7(3):192-3.
2008: Katja Lohmann-Hedrich; A Neumann; André Kleensang; Thora Lohnau; Hiltrud Muhle; Ana Djarmati; Inke R König; Peter P Pramstaller; Eberhard Schwinger; Patricia L Kramer; Andreas Ziegler; Ulrich Stephani; Christine Klein
Evidence for linkage of restless legs syndrome to chromosome 9p: are there two distinct loci?
Neurology 2008;70(9):686-94.
2008: Anne Grünewald; Ana Djarmati; Katja Lohmann-Hedrich; K Farrell; J A Zeller; Niels Allert; F Papengut; B Petersen; Victor S C Fung; C M Sue; D O'Sullivan; N Mahant; Andreas Kupsch; R S Chuang; Karin Wiegers; H Pawlack; Johann Hagenah; Laurie J Ozelius; Ulrich Stephani; Robert Schuit; Anthony E Lang; Jens Volkmann; Alexander Münchau; Christine Klein
Myoclonus-dystonia: significance of large SGCE deletions.
Human mutation 2008;29(2):331-2.
2008: Kathrin Reetz; Hartwig R Siebner; Christian Gaser; J Hagenah; C Buechel; M Kasten; D Petersen; Peter P Pramstaller; Christine Klein; F Binkofksi
Premotor Gray Matter Volume is Associated with Clinical Findings in Idiopathic and Genetically Determined Parkinson's Disease.
The open neuroimaging journal 2008;2():102-5.
2008: Jeanne C Latourelle; Mei Sun; Mark F Lew; Oksana Suchowersky; Christine Klein; Lawrence I Golbe; Margery H Mark; John H Growdon; G Frederick Wooten; Ray L Watts; Mark Guttman; Brad A Racette; Joel S Perlmutter; Anwar Ahmed; Holly A Shill; Carlos Singer; Stefano Goldwurm; Gianni Pezzoli; Michela Zini; Marie H Saint-Hilaire; Audrey E Hendricks; Sally Williamson; Michael W Nagle; Jemma B Wilk; Tiffany Massood; Karen W Huskey; Jason M Laramie; Anita L DeStefano; Kenneth B Baker; Ilia Itin; Irene Litvan; Garth Nicholson; Alastair Corbett; Martha Nance; Edward Drasby; Stuart Isaacson; David J Burn; Patrick F Chinnery; Peter P Pramstaller; Jomana Al-hinti; Anette T Moller; Karen Ostergaard; Scott J Sherman; Richard Roxburgh; Barry Snow; John T Slevin; Franca Cambi; James Gusella; Richard H Myers
The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study.
BMC medicine 2008;6():32.
2007: Ana Djarmati; V Dobricić; M Kecmanović; P Marsh; J Jancić-Stefanović; Christine Klein; M Djurić; Stanka Romac
MECP2 mutations in Serbian Rett syndrome patients.
Acta neurologica Scandinavica 2007;116(6):413-9.
2007: Igor Petrović; Christine Klein; Vladimir S Kostić
Delayed-onset dystonia due to perinatal asphyxia: a prospective study.
Movement disorders : official journal of the Movement Disorder Society 2007;22(16):2426-9.
2007: Christine Klein; Michael G Schlossmacher
Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder.
Neurology 2007;69(22):2093-104.
2007: Tobias Bäumer; Peter P Pramstaller; Hartwig R Siebner; S Schippling; Johann Hagenah; Martin Peller; Christian Gerloff; Christine Klein; Alexander Münchau
Sensorimotor integration is abnormal in asymptomatic Parkin mutation carriers: a TMS study.
Neurology 2007;69(21):1976-81.
2007: Susen Winkler; Inke R König; Katja Lohmann-Hedrich; Peter Vieregge; Vladimir Kostic; Christine Klein
Role of ethnicity on the association of MAPT H1 haplotypes and subhaplotypes in Parkinson's disease.
European journal of human genetics : EJHG 2007;15(11):1163-8.
2007: Michael Orth; Ana Djarmati; Tobias Bäumer; Susen Winkler; Anne Grünewald; Katja Lohmann-Hedrich; Kemal Kabakci; Johann Hagenah; Christine Klein; Alexander Münchau
Autosomal dominant myoclonus-dystonia and Tourette syndrome in a family without linkage to the SGCE gene.
Movement disorders : official journal of the Movement Disorder Society 2007;22(14):2090-6.
2007: Susen Winkler; Johann Hagenah; Sarah J Lincoln; Michael G Heckman; K Haugarvoll; Katja Lohmann-Hedrich; Vladimir Kostic; Matthew J Farrer; Christine Klein
alpha-Synuclein and Parkinson disease susceptibility.
Neurology 2007;69(18):1745-50.
2007: Johann Hagenah; Inke R König; B Becker; Rüdiger Hilker; Meike Kasten; Katja Hedrich; Peter P Pramstaller; Christine Klein; Günter Seidel
Substantia nigra hyperechogenicity correlates with clinical status and number of Parkin mutated alleles.
Journal of neurology 2007;254(10):1407-13.
2007: Ana Djarmati; Miodrag Guzvić; Anne Grünewald; Anthony E Lang; Peter P Pramstaller; David K Simon; Angela M Kaindl; Peter Vieregge; Anders O H Nygren; christian beetz; Katja Hedrich; Christine Klein
Rapid and reliable detection of exon rearrangements in various movement disorders genes by multiplex ligation-dependent probe amplification.
Movement disorders : official journal of the Movement Disorder Society 2007;22(12):1708-14.
2007: J Hübner; Andreas Sprenger; Christine Klein; Johann Hagenah; Holger Rambold; Christine Zühlke; Detlef Kömpf; A Rolfs; H Kimmig; Christoph Helmchen
Eye movement abnormalities in spinocerebellar ataxia type 17 (SCA17).
Neurology 2007;69(11):1160-8.
2007: Ferdinand Binkofski; Kathrin Reetz; Christian Gaser; Rüdiger Hilker; Johann Hagenah; Katja Hedrich; Thilo van Eimeren; A Thiel; Christian Büchel; Peter P Pramstaller; Hartwig R Siebner; Christine Klein
Morphometric fingerprint of asymptomatic Parkin and PINK1 mutation carriers in the basal ganglia.
Neurology 2007;69(9):842-50.
2007: Christine Klein; Katja Lohmann-Hedrich
Impact of recent genetic findings in Parkinson's disease.
Current opinion in neurology 2007;20(4):453-64.
2007: Christine Klein; Vincenzo Bonifati
Dissecting the complexity of frontotemporal dementia: genotypes, phenotypes, and phenocopies.
Neurology 2007;69(2):129-30.
2007: Christine Klein; Katja Lohmann-Hedrich; Ekaterina Rogaeva; Michael G Schlossmacher; Anthony E Lang
Deciphering the role of heterozygous mutations in genes associated with parkinsonism.
Lancet neurology 2007;6(7):652-62.
2007: Johann Hagenah; Kathrin Reetz; Christine Zühlke; A Rolfs; Ferdinand Binkofski; Christine Klein
Predominant dystonia with marked cerebellar atrophy: a rare phenotype in familial dystonia.
Neurology 2007;68(24):2157; author reply 2157-8.
2007: Lorraine N Clark; Eneli Haamer; Helen Mejia-Santana; Juliette Harris; Suzanne Lesage; Alexandra Durr; Sabine Janin Bs; Katja Hedrich; Elan D Louis; Lucien J Cote; Howard Andrews; Stanley Fahn; Cheryl Waters; Blair Ford; Steven Frucht; William Scott; Christine Klein; Alexis Brice; Hanno Roomere; Ruth Ottman; Karen Marder
Construction and validation of a Parkinson's disease mutation genotyping array for the Parkin gene.
Movement disorders : official journal of the Movement Disorder Society 2007;22(7):932-7.
2007: Susanne Steinlechner; Jessica Stahlberg; Birgit Völkel; Ana Djarmati; Johann Hagenah; Anja Hiller; Katja Hedrich; Inke R König; Christine Klein; Rebekka Lencer
Co-occurrence of affective and schizophrenia spectrum disorders with PINK1 mutations.
Journal of neurology, neurosurgery, and psychiatry 2007;78(5):532-5.
2007: Karla Eggert; Ullrich Wüllner; Gisela Antony; Thomas Gasser; Bernd Janetzky; Christine Klein; Ludger Schöls; Wolfgang H Oertel
Data protection in biomaterial banks for Parkinson's disease research: the model of GEPARD (Gene Bank Parkinson's Disease Germany).
Movement disorders : official journal of the Movement Disorder Society 2007;22(5):611-8.
2007: W G Janzarik; Christian P Kratz; Niki Tomas Loges; Heike Olbrich; Christine Klein; T Schäfer; Wolfram Scheurlen; W Roggendorf; C Weiller; C Niemeyer; Rudolf Korinthenberg; Stefan Pfister; Heymut Omran
Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma.
Neuropediatrics 2007;38(2):61-3.
2007: Anne Grünewald; Guido J Breedveld; Katja Lohmann-Hedrich; Christan F Rohé; Inke R König; Johann Hagenah; Nicola Vanacore; Giuseppe Meco; Angelo Antonini; Stefano Goldwurm; Suzanne Lesage; Alexandra Dürr; Ferdinand Binkofski; Hartwig R Siebner; Alexander Münchau; Alexis Brice; Ben A Oostra; Christine Klein; Vincenzo Bonifati
Biological effects of the PINK1 c.1366C>T mutation: implications in Parkinson disease pathogenesis.
Neurogenetics 2007;8(2):103-9.
2007: Allison Brashear; William B Dobyns; Patricia de Carvalho Aguiar; Michel Borg; C J M Frijns; Seema Gollamudi; Andrew Green; João Guimaraes; Bret C Haake; Christine Klein; Gurutz Linazasoro; Alexander Münchau; Deborah Raymond; David Riley; Rachel Saunders-Pullman; Marina A J Tijssen; David Webb; Jacek Zaremba; Susan Bressman; Laurie J Ozelius
The phenotypic spectrum of rapid-onset dystonia-parkinsonism (RDP) and mutations in the ATP1A3 gene.
Brain : a journal of neurology 2007;130(Pt 3):828-35.
2007: C W Hess; Deborah Raymond; Patricia de Carvalho Aguiar; S Frucht; Janet Shriberg; Gary A Heiman; Roger Kurlan; Christine Klein; Susan Bressman; Laurie J Ozelius; Rachel Saunders-Pullman
Myoclonus-dystonia, obsessive-compulsive disorder, and alcohol dependence in SGCE mutation carriers.
Neurology 2007;68(7):522-4.
2007: David Kemlink; Olli Polo; Pasquale Montagna; Federica Provini; Karin Stiasny-Kolster; Wolfgang H Oertel; Al W de Weerd; Sona Nevsimalova; Karel Sonka; Birgit Högl; Birgit Frauscher; Werner Poewe; Claudia Trenkwalder; Peter P Pramstaller; Luigi Ferini-Strambi; Marco Zucconi; Eric Konofal; Isabelle Arnulf; Georgios M Hadjigeorgiou; Svenja Happe; Christine Klein; Anja Hiller; Peter Lichtner; Thomas Meitinger; Betram Müller-Myshok; Juliane Winkelmann
Family-based association study of the restless legs syndrome loci 2 and 3 in a European population.
Movement disorders : official journal of the Movement Disorder Society 2007;22(2):207-12.
2007: Juliane Winkelmann; Oli Polo; Federica Provini; Sona Nevsimalova; David Kemlink; Karel Sonka; Birgit Högl; Werner Poewe; Karin Stiasny-Kolster; Wolfgang H Oertel; Al W de Weerd; Luigi Ferini Strambi; Marco Zucconi; Peter P Pramstaller; Isabelle Arnulf; Claudia Trenkwalder; Christine Klein; Georgios M Hadjigeorgiou; Svenja Happe; David Rye; Pasquale Montagna
Genetics of restless legs syndrome (RLS): State-of-the-art and future directions.
Movement disorders : official journal of the Movement Disorder Society 2007;22 Suppl 18():S449-58.
2007: Claudia Trenkwalder; Ralf Kohnen; Richard Allen; Heike Benes; Luigi Ferini-Strambi; Diego Garcia-Borreguero; Georgios M Hadjigeorgiou; Svenja Happe; Birgit Högl; Magdolna Hornyak; Christine Klein; Alexander Nass; Pasquale Montagna; Wolfgang H Oertel; Shaun O'Keeffe; Walter Paulus; Werner Poewe; Federica Provini; Peter P Pramstaller; Mariusz Sieminski; Karel Sonka; Karin Stiasny-Kolster; Al W de Weerd; Thomas C Wetter; Juliane Winkelmann; Marco Zucconi
Clinical trials in restless legs syndrome--recommendations of the European RLS Study Group (EURLSSG).
Movement disorders : official journal of the Movement Disorder Society 2007;22 Suppl 18():S495-504.
2007: Anja Hiller; Johann Hagenah; Ana Djarmati; Katja Hedrich; Kathrin Reetz; Christiane Schneider-Gold; Wolfram Kress; Alexander Münchau; Christine Klein
Phenotypic spectrum of PINK1-associated parkinsonism in 15 mutation carriers from 1 family.
Movement disorders : official journal of the Movement Disorder Society 2007;22(1):145-7.
2006: J B Wilk; J E Tobin; O Suchowersky; H A Shill; Christine Klein; G F Wooten; M F Lew; M H Mark; M Guttman; Ray L Watts; Carlos Singer; John H Growdon; J C Latourelle; M H Saint-Hilaire; A L DeStefano; R Prakash; S Williamson; C J Berg; M Sun; S Goldwurm; G Pezzoli; B A Racette; J S Perlmutter; A Parsian; K B Baker; M L Giroux; I Litvan; P P Pramstaller; G Nicholson; David J Burn; P F Chinnery; Peter Vieregge; J T Slevin; F Cambi; Marcy E MacDonald; James Gusella; Richard H Myers; Lawrence I Golbe
Herbicide exposure modifies GSTP1 haplotype association to Parkinson onset age: the GenePD Study.
Neurology 2006;67(12):2206-10.
2006: Vladimir S Kostić; Marina Svetel; Kemal Kabakci; Aleksandar Ristić; Igor Petrović; Birgitt Schuele; Norman Kock; Ana Djarmati; Stanka Romac; Christine Klein
Intrafamilial phenotypic and genetic heterogeneity of dystonia.
Journal of the neurological sciences 2006;250(1-2):92-6.
2006: E M J Foncke; M C F Gerrits; F van Ruissen; Frank Baas; Katja Hedrich; C C Tijssen; Christine Klein; Marina A J Tijssen
Distal myoclonus and late onset in a large Dutch family with myoclonus-dystonia.
Neurology 2006;67(9):1677-80.
2006: Elka Stefanova; Ana Djarmati; Dragana Momcilović; Natasa Dragasević; Marina Svetel; Christine Klein; Vladimir S Kostić
Clinical characteristics of paroxysmal nonkinesigenic dyskinesia in Serbian family with Myofibrillogenesis regulator 1 gene mutation.
Movement disorders : official journal of the Movement Disorder Society 2006;21(11):2010-5.
2006: Irene Pichler; Fabio Marroni; Claudia Beu Volpato; James Gusella; Christine Klein; Giorgio Casari; Alessandro De Grandi; Peter P Pramstaller
Linkage analysis identifies a novel locus for restless legs syndrome on chromosome 2q in a South Tyrolean population isolate.
American journal of human genetics 2006;79(4):716-23.
2006: Kathrin Lasek; Rebekka Lencer; Christian Gaser; Johann Hagenah; U Walter; A Wolters; Norman Kock; Susanne Steinlechner; M Nagel; Christine Zühlke; Matthias F Nitschke; K Brockmann; Christine Klein; A Rolfs; Ferdinand Binkofski
Morphological basis for the spectrum of clinical deficits in spinocerebellar ataxia 17 (SCA17).
Brain : a journal of neurology 2006;129(Pt 9):2341-52.
2006: Katja Hedrich; Susen Winkler; Johann Hagenah; Kemal Kabakci; Meike Kasten; Eberhard Schwinger; Jens Volkmann; Peter P Pramstaller; Vladimir Kostic; Peter Vieregge; Christine Klein
Recurrent LRRK2 (Park8) mutations in early-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2006;21(9):1506-10.
2006: Ana Djarmati; Katja Hedrich; Marina Svetel; Thora Lohnau; Eberhard Schwinger; Stanka Romac; Peter P Pramstaller; Vladimir Kostić; Christine Klein
Heterozygous PINK1 mutations: a susceptibility factor for Parkinson disease?
Movement disorders : official journal of the Movement Disorder Society 2006;21(9):1526-30.
2006: A Schmidt; Hans-Christian Jabusch; Eckart Altenmüller; Johann Hagenah; N Brüggemann; Katja Hedrich; Rachel Saunders-Pullman; Susan Bressman; Patricia L Kramer; Christine Klein
Dominantly transmitted focal dystonia in families of patients with musician's cramp.
Neurology 2006;67(4):691-3.
2006: Christoph Helmchen; A Schwekendiek; Peter P Pramstaller; Katja Hedrich; Christine Klein; Holger Rambold
Blink amplitude but not saccadic hypometria indicates carriers of Parkin mutations.
Journal of neurology 2006;253(8):1071-5.
2006: Florian D Vogl; Irene Pichler; Susanna Adel; Gerd K Pinggera; Stefano Bracco; Alessandro De Grandi; Claudia Beu Volpato; paolo aridon; Thomas Mayer; Thomas Meitinger; Christine Klein; Giorgio Casari; Peter P Pramstaller
Restless legs syndrome: epidemiological and clinicogenetic study in a South Tyrolean population isolate.
Movement disorders : official journal of the Movement Disorder Society 2006;21(8):1189-95.
2006: Johann Hagenah; Katja Hedrich; B Becker; Peter P Pramstaller; Günter Seidel; Christine Klein
Distinguishing early-onset PD from dopa-responsive dystonia with transcranial sonography.
Neurology 2006;66(12):1951-2.
2006: Katja Hedrich; Johann Hagenah; Ana Djarmati; Anja Hiller; Thora Lohnau; Kathrin Lasek; Anne Grünewald; Rüdiger Hilker; Susanne Steinlechner; Heather Boston; Norman Kock; Christiane Schneider-Gold; Wolfram Kress; Hartwig R Siebner; Ferdinand Binkofski; Rebekka Lencer; Alexander Münchau; Christine Klein
Clinical spectrum of homozygous and heterozygous PINK1 mutations in a large German family with Parkinson disease: role of a single hit?
Archives of neurology 2006;63(6):833-8.
2006: Mei Sun; Jeanne C Latourelle; G Frederick Wooten; Mark F Lew; Christine Klein; Holly A Shill; Lawrence I Golbe; Margery H Mark; Brad A Racette; Joel S Perlmutter; Abbas Parsian; Mark Guttman; Garth Nicholson; Gang Xu; Jemma B Wilk; Marie H Saint-Hilaire; Anita L DeStefano; Ranjana Prakash; Sally Williamson; Oksana Suchowersky; Nancy Labelle; John H Growdon; Carlos Singer; Ray L Watts; Stefano Goldwurm; Gianni Pezzoli; Kenneth B Baker; Peter P Pramstaller; David J Burn; Patrick F Chinnery; Scott Sherman; Peter Vieregge; Irene Litvan; Tammy Gillis; Marcy E MacDonald; Richard H Myers; James Gusella
Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study.
Archives of neurology 2006;63(6):826-32.
2006: Cindy Zadikoff; Ekaterina Rogaeva; Ana Djarmati; Christine Sato; Shabnam Salehi-Rad; Peter St George-Hyslop; Christine Klein; Anthony E Lang
Homozygous and heterozygous PINK1 mutations: considerations for diagnosis and care of Parkinson's disease patients.
Movement disorders : official journal of the Movement Disorder Society 2006;21(6):875-9.
2006: Christine Klein; Anne Grünewald; Katja Hedrich
Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes.
Neurology 2006;66(7):1129-30; author reply 1129-30.
2006: Matthias F Nitschke; Christian Erdmann; Peter Trillenberg; Andreas Sprenger; Norman Kock; Jürgen Sperner; Christine Klein
Functional MRI reveals activation of a subcortical network in a 5-year-old girl with genetically confirmed myoclonus-dystonia.
Neuropediatrics 2006;37(2):79-82.
2006: C Zadikoff; Anthony E Lang; Christine Klein
The 'essentials' of essential palatal tremor: a reappraisal of the nosology.
Brain : a journal of neurology 2006;129(Pt 4):832-40.
2006: M C F Gerrits; E M J Foncke; Rob J De Haan; Katja Hedrich; Y L C van de Leemput; Frank Baas; Laurie J Ozelius; Johannes D Speelman; Christine Klein; Marina A J Tijssen
Phenotype-genotype correlation in Dutch patients with myoclonus-dystonia.
Neurology 2006;66(5):759-61.
2006: Christine Klein; Michael G Schlossmacher
The genetics of Parkinson disease: Implications for neurological care.
Nature clinical practice. Neurology 2006;2(3):136-46.
2006: Christine Klein
Implications of genetics on the diagnosis and care of patients with Parkinson disease.
Archives of neurology 2006;63(3):328-34.
2006: Susanna Adel; Ana Djarmati; Kemal Kabakci; Irene Pichler; Cordula Eskelson; Thora Lohnau; Norman Kock; Johann Hagenah; Katja Hedrich; Eberhard Schwinger; Patricia L Kramer; Peter P Pramstaller; Christine Klein
Co-occurrence of restless legs syndrome and Parkin mutations in two families.
Movement disorders : official journal of the Movement Disorder Society 2006;21(2):258-63.
2006: Natasa T Dragasević; Biljana Culjković; Christine Klein; Aleksandar Ristić; Milica Keckarević; Ivan Topisirović; Slobodanka Vukosavić; Marina Svetel; Norman Kock; Elka Stefanova; Stanka Romac; Vladimir S Kostić
Frequency analysis and clinical characterization of different types of spinocerebellar ataxia in Serbian patients.
Movement disorders : official journal of the Movement Disorder Society 2006;21(2):187-91.
2006: Laurie J Ozelius; Geetha Senthil; Rachel Saunders-Pullman; Erin Ohmann; Amanda Deligtisch; Michele Tagliati; Ann L Hunt; Christine Klein; Brian Henick; Susan M Hailpern; richard lipton; Jeannie Soto-Valencia; Neil Risch; Susan Bressman
LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews.
The New England journal of medicine 2006;354(4):424-5.
2006: Johan L K Van Hove; J Steyaert; Gert Matthijs; Eric Legius; Paul Theys; R Wevers; Anne Romstad; L B Møller; K Hedrich; D Goriounov; Nenad Blau; Christine Klein; P Casaer
Expanded motor and psychiatric phenotype in autosomal dominant Segawa syndrome due to GTP cyclohydrolase deficiency.
Journal of neurology, neurosurgery, and psychiatry 2006;77(1):18-23.
2005: S Karamohamed; J C Latourelle; B A Racette; J S Perlmutter; G F Wooten; M Lew; Christine Klein; H Shill; Lawrence I Golbe; M H Mark; M Guttman; G Nicholson; J B Wilk; M Saint-Hilaire; A L DeStefano; R Prakash; S Tobin; J Williamson; O Suchowersky; N Labell; B N J Growdon; Carlos Singer; Ray L Watts; S Goldwurm; G Pezzoli; K B Baker; M L Giroux; P P Pramstaller; David J Burn; P Chinnery; S Sherman; Peter Vieregge; I Litvan; James Gusella; Richard H Myers; A Parsian
BDNF genetic variants are associated with onset age of familial Parkinson disease: GenePD Study.
Neurology 2005;65(11):1823-5.
2005: Ana Djarmati; Marina Svetel; Dragana Momcilovic; Vladimir Kostic; Christine Klein
Significance of recurrent mutations in the myofibrillogenesis regulator 1 gene.
Archives of neurology 2005;62(10):1641.
2005: Carsten Buhmann; Ferdinand Binkofski; Christine Klein; Christian Büchel; Thilo van Eimeren; Christian Erdmann; Katja Hedrich; Meike Kasten; Johann Hagenah; Günther Deuschl; Peter P Pramstaller; Hartwig R Siebner
Motor reorganization in asymptomatic carriers of a single mutant Parkin allele: a human model for presymptomatic parkinsonism.
Brain : a journal of neurology 2005;128(Pt 10):2281-90.
2005: Bernhard Kis; Katja Hedrich; Martin Kann; Eberhard Schwinger; D Kömpf; Christine Klein; Peter P Pramstaller
Oculogyric dystonic states in early-onset parkinsonism with basal ganglia calcifications.
Neurology 2005;65(5):761.
2005: Peter P Pramstaller; Michael G Schlossmacher; Thomas S Jacques; Francesco Scaravilli; Cordula Eskelson; Imelda Pepivani; Katja Hedrich; Susanna Adel; Melissa Gonzales-McNeal; Rüdiger Hilker; Patricia L Kramer; Christine Klein
Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers.
Annals of neurology 2005;58(3):411-22.
2005: Christine Klein; Ana Djarmati; Katja Hedrich; Nora Schäfer; Cesa Scaglione; Roberta Marchese; Norman Kock; Birgitt Schuele; Anja Hiller; Thora Lohnau; Susen Winkler; Karin Wiegers; Robert Hering; Peter Bauer; Olaf Riess; Giovanni Abbruzzese; Paolo Martinelli; Peter P Pramstaller
PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism.
European journal of human genetics : EJHG 2005;13(9):1086-93.
2005: Samer Karamohamed; Lawrence I Golbe; M H Mark; Alice Lazzarini; O Suchowersky; N Labelle; Mark Guttman; L J Currie; G F Wooten; M Stacy; M Saint-Hilaire; R G Feldman; J Liu; C M Shoemaker; J B Wilk; A L DeStefano; J C Latourelle; G Xu; Ray L Watts; John H Growdon; M Lew; C Waters; Peter Vieregge; P P Pramstaller; Christine Klein; B A Racette; J S Perlmutter; A Parsian; Carlos Singer; E Montgomery; K Baker; James Gusella; A Herbert; Richard H Myers
Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson's disease from the GenePD study.
Movement disorders : official journal of the Movement Disorder Society 2005;20(9):1188-91.
2005: Daniela Berg; Marc Niwar; Sylvia Maass; Alexander Zimprich; J Carsten Möller; Ullrich Wüllner; Tanja Schmitz-Hübsch; Christine Klein; Eng-King Tan; Ludger Schöls; Laura Marsh; Ted M Dawson; Bernd Janetzky; Thomas Müller; Dirk Woitalla; Vladimir Kostic; Peter P Pramstaller; Wolfgang H Oertel; Peter Bauer; Rejko Krueger; Thomas Gasser; Olaf Riess
Alpha-synuclein and Parkinson's disease: implications from the screening of more than 1,900 patients.
Movement disorders : official journal of the Movement Disorder Society 2005;20(9):1191-4.
2005: Katja Hedrich; Peter P Pramstaller; Katrin Stübke; Anja Hiller; Kemal Kabakci; Sabine Purmann; Meike Kasten; Cesa Scaglione; Eberhard Schwinger; Jens Volkmann; Vladimir Kostic; Peter Vieregge; Paolo Martinelli; Giovanni Abbruzzese; Christine Klein; Christine Zühlke
Premutations in the FMR1 gene as a modifying factor in Parkin-associated Parkinson's disease?
Movement disorders : official journal of the Movement Disorder Society 2005;20(8):1060-2.
2005: Kemal Kabakci; K Isbruch; Karla Schilling; Katja Hedrich; Patricia de Carvalho Aguiar; Laurie J Ozelius; Patricia L Kramer; M H R M Schwarz; Christine Klein
Genetic heterogeneity in rapid onset dystonia-parkinsonism: description of a new family.
Journal of neurology, neurosurgery, and psychiatry 2005;76(6):860-2.
2005: Johann Hagenah; Kai G Kahl; Susanne Steinlechner; Rebekka Lencer; Christine Klein
[Treatment of sialorrhea with botulinum toxin: an overview].
Der Nervenarzt 2005;76(4):418-25.
2005: Johann Hagenah; Rachel Saunders-Pullman; Katja Hedrich; Kemal Kabakci; K Habermann; Karin Wiegers; Kathrin Mohrmann; Thora Lohnau; Deborah Raymond; Peter Vieregge; TG Nygaard; Laurie J Ozelius; Susan Bressman; Christine Klein
High mutation rate in dopa-responsive dystonia: detection with comprehensive GCHI screening.
Neurology 2005;64(5):908-11.
2005: Kai G Kahl; Peter Trillenberg; Andreas Kordon; Rebekka Lencer; Christine Klein; Johann Hagenah
[Pharmacological strategies for clozapine-induced hypersalivation: treatment with botulinum toxin B in one patient and review of the literature].
Der Nervenarzt 2005;76(2):205-8.
2005: Christine Klein
Movement disorders: classifications.
Journal of inherited metabolic disease 2005;28(3):425-39.
2004: Rebekka Lencer; Gunnar Eismann; Meike Kasten; Kemal Kabakci; Verena Geithe; Jenny Grimm; Christine Klein
Family history of primary movement disorders as a predictor for neuroleptic-induced extrapyramidal symptoms.
The British journal of psychiatry : the journal of mental science 2004;185():465-71.
2004: Uwe Walter; Christine Klein; Rüdiger Hilker; Reiner Benecke; Peter P Pramstaller; Dirk Dressler
Brain parenchyma sonography detects preclinical parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2004;19(12):1445-9.
2004: Rachel Saunders-Pullman; N Blau; Keith Hyland; J Zschocke; TG Nygaard; Deborah Raymond; Vicki Shanker; Kathrin Mohrmann; L Arnold; SD Tabbal; D DeLeon; Blair Ford; Mitchell F Brin; S Chouinard; Laurie J Ozelius; Christine Klein; Susan Bressman
Phenylalanine loading as a diagnostic test for DRD: interpreting the utility of the test.
Molecular genetics and metabolism 2004;83(3):207-12.
2004: Katja Hedrich; Cordula Eskelson; Beth Wilmot; Karen Marder; Juliette Harris; Jennifer Garrels; Helen Meija-Santana; Peter Vieregge; Helfried Jacobs; Susan Bressman; Anthony E Lang; Martin Kann; Giovanni Abbruzzese; Paolo Martinelli; Eberhard Schwinger; Laurie J Ozelius; Peter P Pramstaller; Christine Klein; Patricia L Kramer
Distribution, type, and origin of Parkin mutations: review and case studies.
Movement disorders : official journal of the Movement Disorder Society 2004;19(10):1146-57.
2004: Robert Hering; Karsten M Strauss; Xiao Tao; Andreas Bauer; Dirk Woitalla; Eva-Maria Mietz; Slobodanka Petrovic; Peter Bauer; Wilhelm Schaible; Thomas Müller; Ludger Schöls; Christine Klein; Daniela Berg; Philipp T Meyer; Jörg B Schulz; Bernd Wollnik; Liang Tong; Rejko Krüger; Olaf Riess
Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7).
Human mutation 2004;24(4):321-9.
2004: Birgitt Schuele; Norman Kock; Marina Svetel; Natasa Dragasevic; Katja Hedrich; Patricia de Carvalho Aguiar; Liu Liu; Kemal Kabakci; Jennifer Garrels; E-M Meyer; I Berisavac; Eberhard Schwinger; Patricia L Kramer; Laurie J Ozelius; Christine Klein; Vladimir Kostic
Genetic heterogeneity in ten families with myoclonus-dystonia.
Journal of neurology, neurosurgery, and psychiatry 2004;75(8):1181-5.
2004: Fang Wang; Stacy R Denison; Jin-Ping Lai; Leslie A Philips; Damien Montoya; Norman Kock; Birgitt Schuele; Christine Klein; Viji Shridhar; Lewis Roberts; David I Smith
Parkin gene alterations in hepatocellular carcinoma.
Genes, chromosomes & cancer 2004;40(2):85-96.
2004: Ana Djarmati; Katja Hedrich; Marina Svetel; Nora Schäfer; Vladislava Juric; Slobodanka Vukosavic; Robert Hering; Olaf Riess; Stanka Romac; Christine Klein; Vladimir Kostic
Detection of Parkin (PARK2) and DJ1 (PARK7) mutations in early-onset Parkinson disease: Parkin mutation frequency depends on ethnic origin of patients.
Human mutation 2004;23(5):525.
2004: Katja Hedrich; E-M Meyer; Birgitt Schuele; Norman Kock; Patricia de Carvalho Aguiar; Karin Wiegers; J H T M Koelman; Jennifer Garrels; R Dürr; Liu Liu; Eberhard Schwinger; Laurie J Ozelius; B Landwehrmeyer; A Jon Stoessl; Marina A J Tijssen; Christine Klein
Myoclonus-dystonia: detection of novel, recurrent, and de novo SGCE mutations.
Neurology 2004;62(7):1229-31.
2004: Christine Klein
[Genetics of dystonia].
Fortschritte der Neurologie-Psychiatrie 2004;72(4):220-32; quiz 233-4.
2004: Kai G Kahl; Johann Hagenah; Silke Zapf; Peter Trillenberg; Christine Klein; Rebekka Lencer
Botulinum toxin as an effective treatment of clozapine-induced hypersalivation.
Psychopharmacology 2004;173(1-2):229-30.
2004: Kemal Kabakci; Katja Hedrich; J C Leung; Manfred Mitterer; Peter Vieregge; Rebekka Lencer; Johann Hagenah; Jennifer Garrels; K Witt; F Klostermann; Marina Svetel; Jennifer Friedman; Vladimir Kostic; Susan Bressman; Xandra O Breakefield; Laurie J Ozelius; Peter P Pramstaller; Christine Klein
Mutations in DYT1: extension of the phenotypic and mutational spectrum.
Neurology 2004;62(3):395-400.
2004: Katja Hedrich; Ana Djarmati; Nora Schäfer; Robert Hering; Claudia Wellenbrock; Peter H Weiss; Rüdiger Hilker; Peter Vieregge; Laurie J Ozelius; Peter Heutink; Vincenzo Bonifati; Eberhard Schwinger; Anthony E Lang; J Noth; Susan Bressman; Peter P Pramstaller; Olaf Riess; Christine Klein
DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease.
Neurology 2004;62(3):389-94.
2004: Norman Kock; Meike Kasten; Birgitt Schuele; Katja Hedrich; Karin Wiegers; Kemal Kabakci; Johann Hagenah; Peter P Pramstaller; Matthias F Nitschke; Alexander Münchau; Jürgen Sperner; Christine Klein
Clinical and genetic features of myoclonus-dystonia in 3 cases: a video presentation.
Movement disorders : official journal of the Movement Disorder Society 2004;19(2):231-4.
2004: Johann Hagenah; Christine Zühlke; Yorck Hellenbroich; Wolfgang Heide; Christine Klein
Focal dystonia as a presenting sign of spinocerebellar ataxia 17.
Movement disorders : official journal of the Movement Disorder Society 2004;19(2):217-20.
2004: Katja Hedrich; Nora Schäfer; Robert Hering; Johann Hagenah; Andrea J Lanthaler; Eberhard Schwinger; Patricia L Kramer; Laurie J Ozelius; Susan Bressman; Giovanni Abbruzzese; Paolo Martinelli; Vladimir Kostic; Peter P Pramstaller; Peter Vieregge; Olaf Riess; Christine Klein
The R98Q variation in DJ-1 represents a rare polymorphism.
Annals of neurology 2004;55(1):145; author reply 145-6.
2003: S Karamohamed; A L DeStefano; J B Wilk; C M Shoemaker; Lawrence I Golbe; M H Mark; Alice Lazzarini; O Suchowersky; N Labelle; M Guttman; L J Currie; G F Wooten; M Stacy; M Saint-Hilaire; R G Feldman; K M Sullivan; G Xu; Ray L Watts; John H Growdon; M Lew; C Waters; Peter Vieregge; P P Pramstaller; Christine Klein; B A Racette; J S Perlmutter; A Parsian; Carlos Singer; E Montgomery; K Baker; James Gusella; S J Fink; Richard H Myers; A Herbert
A haplotype at the PARK3 locus influences onset age for Parkinson's disease: the GenePD study.
Neurology 2003;61(11):1557-61.
2003: Stacy R Denison; Fang Wang; Nicole A Becker; Birgitt Schuele; Norman Kock; Leslie A Phillips; Christine Klein; David I Smith
Alterations in the common fragile site gene Parkin in ovarian and other cancers.
Oncogene 2003;22(51):8370-8.
2003: Claudia Wellenbrock; Katja Hedrich; Nora Schäfer; Meike Kasten; Helfried Jacobs; Eberhard Schwinger; Johann Hagenah; Peter P Pramstaller; Peter Vieregge; Christine Klein
NR4A2 mutations are rare among European patients with familial Parkinson's disease.
Annals of neurology 2003;54(3):415.
2003: Christine Klein; Katja Hedrich; Claudia Wellenbrock; Martin Kann; Juliette Harris; Karen Marder; Anthony E Lang; Eberhard Schwinger; Laurie J Ozelius; Peter Vieregge; Peter P Pramstaller; Patricia L Kramer
Frequency of parkin mutations in late-onset Parkinson's disease.
Annals of neurology 2003;54(3):415-6; author reply 416-7.
2003: E M J Foncke; Christine Klein; J H T M Koelman; Patricia L Kramer; Karla Schilling; Birgitt Müller; Jennifer Garrels; Patricia de Carvalho Aguiar; Liu Liu; A de Froe; Johannes D Speelman; Laurie J Ozelius; Marina A J Tijssen
Hereditary myoclonus-dystonia associated with epilepsy.
Neurology 2003;60(12):1988-90.
2003: Sarah J Lincoln; Joseph Wiley; Timothy Lynch; J William Langston; R Chen; Anthony E Lang; Ekaterina Rogaeva; Daniel S Sa; Renato P Munhoz; J Harris; Karen Marder; Christine Klein; Gina Bisceglio; Jennifer Hussey; A West; Mary Hulihan; John Hardy; Matthew J Farrer
Parkin-proven disease: common founders but divergent phenotypes.
Neurology 2003;60(10):1605-10.
2003: S Maniak; MG Sieberer; Johann Hagenah; Christine Klein; Peter Vieregge
Focal and segmental primary dystonia in north-western Germany--a clinico-genetic study.
Acta neurologica Scandinavica 2003;107(3):228-32.
2002: Christine Klein; Katja Hedrich; K Kabakçi; Kathrin Mohrmann; Karin Wiegers; Olfert Landt; Johann Hagenah; Eberhard Schwinger; Peter P Pramstaller; Laurie J Ozelius; K Gucuyener; Sabiha Aysun; E Demir
Exon deletions in the GCHI gene in two of four Turkish families with dopa-responsive dystonia.
Neurology 2002;59(11):1783-6.
2002: Birgitt Müller; Katja Hedrich; Norman Kock; Natasa Dragasevic; Marina Svetel; Jennifer Garrels; Olfert Landt; Matthias F Nitschke; Peter P Pramstaller; Wolf Reik; Eberhard Schwinger; Jürgen Sperner; Laurie J Ozelius; Vladimir Kostic; Christine Klein
Evidence that paternal expression of the epsilon-sarcoglycan gene accounts for reduced penetrance in myoclonus-dystonia.
American journal of human genetics 2002;71(6):1303-11.
2002: Christine Klein; Liu Liu; Dana Doheny; Norman Kock; Birgitt Müller; Patricia de Carvalho Aguiar; Joanne Leung; Deborah de Leon; Susan Bressman; Jeremy Silverman; Christopher Smith; Fabio Danisi; Chris Morrison; Ruth H Walker; Miodrag Velickovic; Eberhard Schwinger; Patricia L Kramer; Xandra O Breakefield; Mitchell F Brin; Laurie J Ozelius
Epsilon-sarcoglycan mutations found in combination with other dystonia gene mutations.
Annals of neurology 2002;52(5):675-9.
2002: Dana Doheny; Fabio Danisi; Christopher Smith; C Morrison; Miodrag Velickovic; Deborah de Leon; Susan Bressman; Joanne Leung; Laurie J Ozelius; Christine Klein; Xandra O Breakefield; Mitchell F Brin; Jeremy Silverman
Clinical findings of a myoclonus-dystonia family with two distinct mutations.
Neurology 2002;59(8):1244-6.
2002: Dana Doheny; Mitchell F Brin; Chris E Morrison; C J Smith; Ruth H Walker; S Abbasi; Birgitt Müller; Jennifer Garrels; Liu Liu; Patricia de Carvalho Aguiar; Karla Schilling; Patricia L Kramer; Deborah de Leon; Deborah Raymond; Rachel Saunders-Pullman; Christine Klein; Susan Bressman; B Schmand; Marina A J Tijssen; Laurie J Ozelius; Jeremy Silverman
Phenotypic features of myoclonus-dystonia in three kindreds.
Neurology 2002;59(8):1187-96.
2002: Sarah J Augood; Zane R Hollingsworth; David S Albers; L Yang; J-C Leung; B Muller; Christine Klein; Xandra O Breakefield; David G Standaert
Dopamine transmission in DYT1 dystonia: a biochemical and autoradiographical study.
Neurology 2002;59(3):445-8.
2002: Stefanie Bubel; Verena Peters; Christine Klein; Rolf Hackler; Juergen R Schaefer; J Hagenah; Georg F Hoffmann; Peter Vieregge
[CDG (congenital disorders of glycosylation). Differential hereditary ataxia in adulthood diagnosis].
Der Nervenarzt 2002;73(8):754-60.
2002: Norman Kock; Birgitt Müller; Peter Vieregge; Peter P Pramstaller; Karen Marder; Giovanni Abbruzzese; Paolo Martinelli; Anthony E Lang; Helfried Jacobs; Johann Hagenah; Juliette Harris; Helen Meija-Santana; Stanley Fahn; Katja Hedrich; Martin Kann; Ulrike Gehlken; Biljana Culjkovic; Eberhard Schwinger; Zbigniew K Wszolek; Christine Zühlke; Christine Klein
Role of SCA2 mutations in early- and late-onset dopa-responsive parkinsonism.
Annals of neurology 2002;52(2):257-8; author reply 258.
2002: Christine Klein; Laurie J Ozelius
Dystonia: clinical features, genetics, and treatment.
Current opinion in neurology 2002;15(4):491-7.
2002: Pramod Kumar Pal; Joanne Leung; Katya Hedrich; Ali Samii; Abraham Lieberman; Paul A Nausieda; Donald B Calne; Xandra O Breakefield; Christine Klein; A Jon Stoessl
[18F]-Dopa positron emission tomography imaging in early-stage, non-parkin juvenile parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2002;17(4):789-94.
2002: Norman Kock; Biljana Culjkovic; Susanna Maniak; Karla Schilling; Birgitt Müller; Christine Zühlke; Laurie J Ozelius; Christine Klein; Peter P Pramstaller; Patricia L Kramer
Mode of inheritance and susceptibility locus for restless legs syndrome, on chromosome 12q.
American journal of human genetics 2002;71(1):205-8; author reply 208.
2002: Bernhard Kis; A Schrag; Y Ben-Shlomo; Christine Klein; A Gasperi; F Spoegler; Rudolf Schoenhuber; Peter P Pramstaller
Novel three-stage ascertainment method: prevalence of PD and parkinsonism in South Tyrol, Italy.
Neurology 2002;58(12):1820-5.
2002: Martin Kann; Helfried Jacobs; Kathrin Mohrmann; Kirsten Schumacher; Katja Hedrich; Jennifer Garrels; Karin Wiegers; Eberhard Schwinger; Peter P Pramstaller; Xandra O Breakefield; Laurie J Ozelius; Peter Vieregge; Christine Klein
Role of parkin mutations in 111 community-based patients with early-onset parkinsonism.
Annals of neurology 2002;51(5):621-5.
2002: Anita L DeStefano; Mark F Lew; Lawrence I Golbe; Margery H Mark; Alice Lazzarini; Mark Guttman; Erwin Montgomery; Cheryl H Waters; Carlos Singer; Ray L Watts; Lillian J Currie; G Frederick Wooten; Nancy E Maher; Jemma B Wilk; Kristin M Sullivan; Karen M Slater; Marie H Saint-Hilaire; Robert G Feldman; Oksana Suchowersky; Anne-Louise Lafontaine; Nancy Labelle; John H Growdon; Peter Vieregge; Peter P Pramstaller; Christine Klein; Jean P Hubble; Carson R Reider; Mark Stacy; Marcy E MacDonald; James Gusella; Richard H Myers
PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study.
American journal of human genetics 2002;70(5):1089-95.
2002: Katja Hedrich; Karen Marder; Juliette Harris; Martin Kann; T Lynch; Helen Meija-Santana; Peter P Pramstaller; Eberhard Schwinger; Susan Bressman; Stanley Fahn; Christine Klein
Evaluation of 50 probands with early-onset Parkinson's disease for Parkin mutations.
Neurology 2002;58(8):1239-46.
2002: Rüdiger Hilker; Christine Klein; Katja Hedrich; Laurie J Ozelius; Peter Vieregge; Karl Herholz; Peter P Pramstaller; Wolf-Dieter Heiss
The striatal dopaminergic deficit is dependent on the number of mutant alleles in a family with mutations in the parkin gene: evidence for enzymatic parkin function in humans.
Neuroscience letters 2002;323(1):50-4.
2002: Martin Kann; Katja Hedrich; Peter Vieregge; Helfried Jacobs; B Müller; Norman Kock; Eberhard Schwinger; Christine Klein; Karen Marder; Juliette Harris; Helen Meija-Santana; Susan Bressman; Laurie J Ozelius; Anthony E Lang; Peter P Pramstaller
The parkin gene is not involved in late-onset Parkinson's disease.
Neurology 2002;58(5):835; author reply 835.
2002: Peter P Pramstaller; G Künig; Klaus L Leenders; Martin Kann; Katja Hedrich; Peter Vieregge; Christopher G Goetz; Christine Klein
Parkin mutations in a patient with hemiparkinsonism-hemiatrophy: a clinical-genetic and PET study.
Neurology 2002;58(5):808-10.
2002: Peter P Pramstaller; Bernhard Kis; Cordula Eskelson; Katja Hedrich; Monika Scherer; Eberhard Schwinger; Xandra O Breakefield; Patricia L Kramer; Laurie J Ozelius; Christine Klein
Phenotypic variability in a large kindred (Family LA) with deletions in the parkin gene.
Movement disorders : official journal of the Movement Disorder Society 2002;17(2):424-6.
2002: Roberta Vitaliani; Tomaso Scaravilli; Eduard Egarter-Vigl; Bruno Giometto; Christine Klein; Francesco Scaravilli; Shu F An; Peter P Pramstaller
The pathology of the spinal cord in progressive supranuclear palsy.
Journal of neuropathology and experimental neurology 2002;61(3):268-74.
2002: Rachel Saunders-Pullman; Janet Shriberg; Gary A Heiman; Deborah Raymond; K Wendt; Patricia L Kramer; Karla Schilling; Roger Kurlan; Christine Klein; Laurie J Ozelius; Neil J Risch; Susan Bressman
Myoclonus dystonia: possible association with obsessive-compulsive disorder and alcohol dependence.
Neurology 2002;58(2):242-5.
2002: NE Maher; Lawrence I Golbe; Alice Lazzarini; Margery H Mark; Lillian J Currie; G Frederick Wooten; Marie H Saint-Hilaire; Jemma B Wilk; Jeannine Volcjak; J E Maher; Robert G Feldman; Mark Guttman; Mark Lew; C H Waters; S Schuman; Oksana Suchowersky; Anne-Louise Lafontaine; Nancy Labelle; Peter Vieregge; P P Pramstaller; Christine Klein; Jean P Hubble; C Reider; John H Growdon; Ray L Watts; E Montgomery; K Baker; Carlos Singer; Mark Stacy; Richard H Myers
Epidemiologic study of 203 sibling pairs with Parkinson's disease: the GenePD study.
Neurology 2002;58(1):79-84.
2001: Matthias F Nitschke; G Krüger; H Bruhn; Christine Klein; Eckard Gehrking; Karl Wessel; J Frahm; Peter Vieregge
Voluntary palatal tremor is associated with hyperactivation of the inferior olive: a functional magnetic resonance imaging study.
Movement disorders : official journal of the Movement Disorder Society 2001;16(6):1193-5.
2001: Anita L DeStefano; Lawrence I Golbe; Margery H Mark; Alice Lazzarini; NE Maher; Marie H Saint-Hilaire; Robert G Feldman; Mark Guttman; Ray L Watts; Oksana Suchowersky; Anne-Louise Lafontaine; Nancy Labelle; Mark Lew; C H Waters; John H Growdon; Carlos Singer; Lillian J Currie; G Frederick Wooten; Peter Vieregge; P P Pramstaller; Christine Klein; Jean P Hubble; Mark Stacy; E Montgomery; Marcy E MacDonald; James Gusella; Richard H Myers
Genome-wide scan for Parkinson's disease: the GenePD Study.
Neurology 2001;57(6):1124-6.
2001: Katja Hedrich; Martin Kann; A J Lanthaler; Andreas Dalski; Cordula Eskelson; Olfert Landt; Eberhard Schwinger; Peter Vieregge; Anthony E Lang; Xandra O Breakefield; Laurie J Ozelius; Peter P Pramstaller; Christine Klein
The importance of gene dosage studies: mutational analysis of the parkin gene in early-onset parkinsonism.
Human molecular genetics 2001;10(16):1649-56.
2001: J C Leung; Christine Klein; Jennifer Friedman; Peter Vieregge; H Jacobs; Dana Doheny; Christoph Kamm; D DeLeon; Peter P Pramstaller; John B Penney; M Eisengart; Joseph Jankovic; T Gasser; Susan Bressman; David P Corey; Patricia L Kramer; Mitchell F Brin; Laurie J Ozelius; Xandra O Breakefield
Novel mutation in the TOR1A (DYT1) gene in atypical early onset dystonia and polymorphisms in dystonia and early onset parkinsonism.
Neurogenetics 2001;3(3):133-43.
2001: Christine Klein
[The genetics of Parkinson syndrome].
Praxis 2001;90(23):1015-23.
2001: Christine Zühlke; Yorck Hellenbroich; Andreas Dalski; N Kononowa; Johann Hagenah; Peter Vieregge; Olaf Riess; Christine Klein; Eberhard Schwinger
Different types of repeat expansion in the TATA-binding protein gene are associated with a new form of inherited ataxia.
European journal of human genetics : EJHG 2001;9(3):160-4.
2001: Rüdiger Hilker; Christine Klein; Mehran Ghaemi; Bernhard Kis; T Strotmann; Laurie J Ozelius; O Lenz; Peter Vieregge; Karl Herholz; Wolf-Dieter Heiss; Peter P Pramstaller
Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene.
Annals of neurology 2001;49(3):367-76.
2000: Bernhard Kis; I Heberlein; Johann Hagenah; Helfried Jacobs; Christine Klein; Peter Vieregge
Neuropsychological abnormalities in first degree relatives of patients with familial Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 2000;69(6):838.
2000: J R Friedman; Christine Klein; J Leung; H Woodward; Laurie J Ozelius; Xandra O Breakefield; M E Charness
The GAG deletion of the DYT1 gene is infrequent in musicians with focal dystonia.
Neurology 2000;55(9):1417-8.
2000: Christine Klein; Karla Schilling; Rachel Saunders-Pullman; Jennifer Garrels; Xandra O Breakefield; Mitchell F Brin; D DeLeon; Dana Doheny; Stanley Fahn; J S Fink; Lars Forsgren; Jennifer Friedman; S Frucht; Juliette Harris; Gösta Holmgren; Bernhard Kis; Roger Kurlan; M Kyllerman; Anthony E Lang; Joanne Leung; Deborah Raymond; J D Robishaw; G Sanner; Eberhard Schwinger; Rowena Tabamo; Michele Tagliati
A major locus for myoclonus-dystonia maps to chromosome 7q in eight families.
American journal of human genetics 2000;67(5):1314-9.
2000: Christine Klein; K Schumacher; Helfried Jacobs; Johann Hagenah; Bernhard Kis; Jennifer Garrels; Eberhard Schwinger; Laurie J Ozelius; Peter P Pramstaller; Peter Vieregge; Patricia L Kramer
Association studies of Parkinson's disease and parkin polymorphisms.
Annals of neurology 2000;48(1):126-7.
2000: Christine Klein; Peter P Pramstaller; Bernhard Kis; C C Page; Martin Kann; Joanne Leung; H Woodward; C C Castellan; M Scherer; Peter Vieregge; Xandra O Breakefield; Patricia L Kramer; Laurie J Ozelius
Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: expanding the phenotype.
Annals of neurology 2000;48(1):65-71.
2000: Christine Klein; Martin Kann; Bernhard Kis; Peter P Pramstaller; Xandra O Breakefield; Laurie J Ozelius; Peter Vieregge
[Genetics of dystonia].
Der Nervenarzt 2000;71(6):431-41.
2000: Susan Bressman; C Sabatti; Deborah Raymond; Deborah de Leon; Christine Klein; Patricia L Kramer; Mitchell F Brin; Stanley Fahn; Xandra O Breakefield; Laurie J Ozelius; Neil J Risch
The DYT1 phenotype and guidelines for diagnostic testing.
Neurology 2000;54(9):1746-52.
2000: Christine Klein; Nadia Gurvich; Miguel Sena-Esteves; Susan Bressman; Mitchell F Brin; Barbara J Ebersole; S Fink; Lars Forsgren; Jennifer Friedman; D Grimes; Gösta Holmgren; M Kyllerman; Anthony E Lang; Deborah de Leon; Joanne Leung; C Prioleau; Deborah Raymond; G Sanner; Rachel Saunders-Pullman; Peter Vieregge; J Wahlström; Xandra O Breakefield; Patricia L Kramer; Laurie J Ozelius; Stuart C Sealfon
Evaluation of the role of the D2 dopamine receptor in myoclonus dystonia.
Annals of neurology 2000;47(3):369-73.
1999: Laurie J Ozelius; CE Page; Christine Klein; Jeffrey W Hewett; M Mineta; Joanne Leung; Christo Shalish; Susan Bressman; Deborah de Leon; Mitchell F Brin; Stanley Fahn; David P Corey; Xandra O Breakefield
The TOR1A (DYT1) gene family and its role in early onset torsion dystonia.
Genomics 1999;62(3):377-84.
1999: MG Sieberer; Peter Vieregge; Christine Klein; Laurie J Ozelius; Klaus-Peter Wandinger
Concordant late onset of craniocervical dystonia in a pair of monozygotic twins.
Movement disorders : official journal of the Movement Disorder Society 1999;14(6):1040-3.
1999: TG Nygaard; Deborah Raymond; C Chen; Ichizo Nishino; Paul Greene; D Jennings; Gary A Heiman; Christine Klein; Rachel Saunders-Pullman; Patricia L Kramer; Laurie J Ozelius; Susan Bressman
Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31.
Annals of neurology 1999;46(5):794-8.
1999: Peter Vieregge; Johann Hagenah; I Heberlein; Christine Klein; H P Ludin
Parkinson's disease in twins: a follow-up study.
Neurology 1999;53(3):566-72.
1999: Patricia L Kramer; M Mineta; Christine Klein; Karla Schilling; Deborah de Leon; Martin R Farlow; Xandra O Breakefield; Susan Bressman; W B Dobyns; Laurie J Ozelius; Allison Brashear
Rapid-onset dystonia-parkinsonism: linkage to chromosome 19q13.
Annals of neurology 1999;46(2):176-82.
1999: Christine Klein; Peter Vieregge; Johann Hagenah; MG Sieberer; E Doyle; H Jacobs; T Gasser; Xandra O Breakefield; Neil J Risch; Laurie J Ozelius
Search for the PARK3 founder haplotype in a large cohort of patients with Parkinson's disease from northern Germany.
Annals of human genetics 1999;63(Pt 4):285-91.
1999: Christine Klein; Mitchell F Brin; Patricia L Kramer; Miguel Sena-Esteves; Deborah de Leon; Dana Doheny; Susan Bressman; Stanley Fahn; Xandra O Breakefield; Laurie J Ozelius
Association of a missense change in the D2 dopamine receptor with myoclonus dystonia.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5173-6.
1999: Christine Klein; CE Page; Peter LeWitt; Mark Forrest Gordon; Deborah de Leon; Yasser Awaad; Xandra O Breakefield; Mitchell F Brin; Laurie J Ozelius
Genetic analysis of three patients with an 18p- syndrome and dystonia.
Neurology 1999;52(3):649-51.
1999: Christine Klein; Xandra O Breakefield; Laurie J Ozelius
Genetics of primary dystonia.
Seminars in neurology 1999;19(3):271-80.
1999: Christine Klein; Jennifer Friedman; Susan Bressman; Peter Vieregge; Mitchell F Brin; Peter P Pramstaller; Deborah de Leon; Johann Hagenah; MG Sieberer; C Fleet; Rosemary Kiely; W Xin; Xandra O Breakefield; Laurie J Ozelius; Katherine B Sims
Genetic testing for early-onset torsion dystonia (DYT1): introduction of a simple screening method, experiences from testing of a large patient cohort, and ethical aspects.
Genetic testing 1999;3(4):323-8.
1999: Johann Hagenah; Christine Klein; MG Sieberer; Peter Vieregge
Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: further clinical evidence.
Journal of neural transmission (Vienna, Austria : 1996) 1999;106(3-4):301-7.
1998: Christine Klein; Laurie J Ozelius; Johann Hagenah; Xandra O Breakefield; Neil J Risch; Peter Vieregge
Search for a founder mutation in idiopathic focal dystonia from Northern Germany.
American journal of human genetics 1998;63(6):1777-82.
1998: Christine Klein; Peter Vieregge; Wolfgang Heide; B Kemper; M Hagedorn-Greiwe; Johann Hagenah; Clemens Vollmer; Xandra O Breakefield; Detlef Kömpf; Laurie J Ozelius
Exclusion of chromosome regions 6p12 and 15q11, but not chromosome region 7p11, in a German family with autosomal dominant congenital nystagmus.
Genomics 1998;54(1):176-7.
1998: Christine Klein; Peter P Pramstaller; C C Castellan; Xandra O Breakefield; Patricia L Kramer; Laurie J Ozelius
Clinical and genetic evaluation of a family with a mixed dystonia phenotype from South Tyrol.
Annals of neurology 1998;44(3):394-8.
1998: Christine Klein; Peter Vieregge
[Non-epileptic paroxysmal movement disorders].
Der Nervenarzt 1998;69(8):647-59.
1998: Christine Klein; Mitchell F Brin; Deborah de Leon; Svetlana A Limborska; Irina A Ivanova-Smolenskaya; Susan Bressman; A Friedman; Elena D Markova; Neil J Risch; Xandra O Breakefield; Laurie J Ozelius
De novo mutations (GAG deletion) in the DYT1 gene in two non-Jewish patients with early-onset dystonia.
Human molecular genetics 1998;7(7):1133-6.
1998: Christine Klein; Peter Vieregge
Fahr's disease--far from a disease.
Movement disorders : official journal of the Movement Disorder Society 1998;13(3):620-1.
1998: Christine Klein; Eckard Gehrking; Peter Vieregge
Voluntary palatal tremor in two siblings.
Movement disorders : official journal of the Movement Disorder Society 1998;13(3):545-8.
1997: Zbigniew K Wszolek; Peter Vieregge; Ryan Uitti; Thomas Gasser; O Yasuhara; Patrick L McGeer; K Berry; Donald B Calne; F J Vingerhoets; Christine Klein; Ronald F Pfeiffer
German-Canadian family (family A) with parkinsonism, amyotrophy, and dementia - Longitudinal observations.
Parkinsonism & related disorders 1997;3(3):125-39.
1997: Christine Klein; R Brown; Gregor Wenning; Niall Quinn
The "cold hands sign" in multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society 1997;12(4):514-8.
1997: Peter Vieregge; Christine Klein; Eckard Gehrking; D Körtke; Detlef Kömpf
The diagnosis of 'essential palatal tremor'.
Neurology 1997;49(1):248-9.
1997: Christine Klein; Detlef Kömpf; U Pulkowski; A Moser; Peter Vieregge
A study of visual hallucinations in patients with Parkinson's disease.
Journal of neurology 1997;244(6):371-7.
1997: Christine Klein; Peter Vieregge; Detlef Kömpf
Paroxysmal choreoathetosis in a patient with idiopathic basal ganglia calcification, chorea, and dystonia.
Movement disorders : official journal of the Movement Disorder Society 1997;12(2):254-5.
1997: Peter Vieregge; H Stolze; Christine Klein; I Heberlein
Gait quantitation in Parkinson's disease--locomotor disability and correlation to clinical rating scales.
Journal of neural transmission (Vienna, Austria : 1996) 1997;104(2-3):237-48.
1982: R Sandyk; Christine Klein
Progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome). A case report.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1982;62(18):667-8.