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Christine Klein

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
van der Vegt J P M; van Nuenen B F L; Bloem B R; Klein C; Siebner H R
Imaging the impact of genes on Parkinson's disease.
Klein Christine; Schneider Susanne A; Lang Anthony E
Hereditary parkinsonism: Parkinson disease look-alikes--an algorithm for clinicians to "PARK" genes and beyond.
Djarmati Ana; Hagenah Johann; Reetz Kathrin; Winkler Susen; Behrens Maria Isabel; Pawlack Heike; Lohmann Katja; Ramirez Alfredo; Tadic Vera; Brüggemann Norbert; Berg Daniela; Siebner Hartwig R; Lang Anthony E; Pramstaller Peter P; Binkofski Ferdinand; Kostic Vladimir S; Volkmann Jens; Gasser Thomas; Klein Christine
ATP13A2 variants in early-onset Parkinson's disease patients and controls.

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All Publications

2009: van der Vegt J P M; van Nuenen B F L; Bloem B R; Klein C; Siebner H R
Imaging the impact of genes on Parkinson's disease.
Neuroscience 2009;164(1):191-204.
2009: Klein Christine; Schneider Susanne A; Lang Anthony E
Hereditary parkinsonism: Parkinson disease look-alikes--an algorithm for clinicians to "PARK" genes and beyond.
Movement disorders : official journal of the Movement Disorder Society 2009;24(14):2042-58.
2009: Djarmati Ana; Hagenah Johann; Reetz Kathrin; Winkler Susen; Behrens Maria Isabel; Pawlack Heike; Lohmann Katja; Ramirez Alfredo; Tadic Vera; Brüggemann Norbert; Berg Daniela; Siebner Hartwig R; Lang Anthony E; Pramstaller Peter P; Binkofski Ferdinand; Kostic Vladimir S; Volkmann Jens; Gasser Thomas; Klein Christine
ATP13A2 variants in early-onset Parkinson's disease patients and controls.
Movement disorders : official journal of the Movement Disorder Society 2009;24(14):2104-11.
2009: Lencer R; Steinlechner S; Stahlberg J; Rehling H; Orth M; Baeumer T; Rumpf H-J; Meyer C; Klein C; Muenchau A; Hagenah J
Primary focal dystonia: evidence for distinct neuropsychiatric and personality profiles.
Journal of neurology, neurosurgery, and psychiatry 2009;80(10):1176-9.
2009: Grünewald A; Gegg M E; Taanman J-W; King R H; Kock N; Klein C; Schapira A H V
Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology.
Experimental neurology 2009;219(1):266-73.
2009: Hertel Susanne; Sprenger Andreas; Klein Christine; Kömpf Detlef; Helmchen Christoph; Kimmig Hubert
Different saccadic abnormalities in PINK1 mutation carriers and in patients with non-genetic Parkinson's disease.
Journal of neurology 2009;256(7):1192-4.
2009: Brüggemann Norbert; Mitterer Manfred; Lanthaler Andrea J; Djarmati Ana; Hagenah Johann; Wiegers Karin; Winkler Susen; Pawlack Heike; Lohnau Thora; Pramstaller Peter P; Klein Christine; Lohmann Katja
Frequency of heterozygous Parkin mutations in healthy subjects: need for careful prospective follow-up examination of mutation carriers.
Parkinsonism & related disorders 2009;15(6):425-9.
2009: Gierthmühlen J; Lienau F; Maag R; Hagenah J M; Deuschl G; Fritzer E; Klein C; Baron R; Helmchen C
Somatosensory processing in a German family with PINK1 mutations: its potential role in Parkinson disease.
Journal of neurology, neurosurgery, and psychiatry 2009;80(5):571-4.
2009: Paus Sebastian; Gadow Franziska; Knapp Michael; Klein Christine; Klockgether Thomas; Wüllner Ullrich
Motor complications in patients form the German Competence Network on Parkinson's disease and the DRD3 Ser9Gly polymorphism.
Movement disorders : official journal of the Movement Disorder Society 2009;24(7):1080-4.
2009: Djarmati Ana; Schneider Susanne A; Lohmann Katja; Winkler Susen; Pawlack Heike; Hagenah Johann; Brüggemann Norbert; Zittel Simone; Fuchs Tania; Rakovic Aleksandar; Schmidt Alexander; Jabusch Hans-Christian; Wilcox Robert; Kostic Vladimir S; Siebner Hartwig; Altenmüller Eckart; Münchau Alexander; Ozelius Laurie J; Klein Christine
Mutations in THAP1 (DYT6) and generalised dystonia with prominent spasmodic dysphonia: a genetic screening study.
Lancet neurology 2009;8(5):447-52.
2009: Brüggemann N; Kock N; Lohmann K; König I R; Rakovic A; Hagenah J; Schmidt A; Ziegler A; Jabusch H C; Siebner H; Altenmüller E; Münchau A; Klein C
The D216H variant in the DYT1 gene: a susceptibility factor for dystonia in familial cases?
Neurology 2009;72(16):1441-3.
2009: Schmidt A; Jabusch H-C; Altenmüller E; Hagenah J; Brüggemann N; Lohmann K; Enders L; Kramer P L; Saunders-Pullman R; Bressman S B; Münchau A; Klein C
Etiology of musician's dystonia: familial or environmental?
Neurology 2009;72(14):1248-54.
2009: van Nuenen B F L; Weiss M M; Bloem B R; Reetz K; van Eimeren T; Lohmann K; Hagenah J; Pramstaller P P; Binkofski F; Klein C; Siebner H R
Heterozygous carriers of a Parkin or PINK1 mutation share a common functional endophenotype.
Neurology 2009;72(12):1041-7.
2009: Rakovic Aleksandar; Stiller Barbara; Djarmati Ana; Flaquer Antonia; Freudenberg Jan; Toliat Mohammad-Reza; Linnebank Michael; Kostic Vladimir; Lohmann Katja; Paus Sebastian; Nürnberg Peter; Kubisch Christian; Klein Christine; Wüllner Ullrich; Ramirez Alfredo
Genetic association study of the P-type ATPase ATP13A2 in late-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2009;24(3):429-33.
2009: Zschiedrich Katja; König Inke R; Brüggemann Norbert; Kock Norman; Kasten Meike; Leenders Klaus L; Kostic Vladimir; Vieregge Peter; Ziegler Andreas; Klein Christine; Lohmann Katja
MDR1 variants and risk of Parkinson disease. Association with pesticide exposure?
Journal of neurology 2009;256(1):115-20.
2009: Klein Christine; Lohmann Katja
Parkinson disease(s): is "Parkin disease" a distinct clinical entity?
Neurology 2009;72(2):106-7.
2009: Reetz Kathrin; Gaser Christian; Klein Christine; Hagenah Johannes; Büchel Christian; Gottschalk Stefan; Pramstaller Peter P; Siebner Hartwig R; Binkofski Ferdinand
Structural findings in the basal ganglia in genetically determined and idiopathic Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2009;24(1):99-103.
2008: Brueggemann N; Odin P; Gruenewald A; Tadic V; Hagenah J; Seidel G; Lohmann K; Klein C; Djarmati A
Re: Alpha-synuclein gene duplication is present in sporadic Parkinson disease.
Neurology 2008;71(16):1294; author reply 1294.
2008: Guettard Emilie; Portnoi Marie-France; Lohmann-Hedrich Katja; Keren Boris; Rossignol Sylvie; Winkler Susen; El Kamel Imen; Leu Smaranda; Apartis Emmanuelle; Vidailhet Marie; Klein Christine; Roze Emmanuel
Myoclonus-dystonia due to maternal uniparental disomy.
Archives of neurology 2008;65(10):1380-5.
2008: Schmidt A; Schneider S A; Hagenah J; Klein C
[Dystonia]
Der Nervenarzt 2008;79 Suppl 2():53-63; quiz 64-5.
2008: Hagenah J M; Becker B; Brüggemann N; Djarmati A; Lohmann K; Sprenger A; Klein C; Seidel G
Transcranial sonography findings in a large family with homozygous and heterozygous PINK1 mutations.
Journal of neurology, neurosurgery, and psychiatry 2008;79(9):1071-4.
2008: McNicoll Christopher F; Latourelle Jeanne C; MacDonald Marcy E; Lew Mark F; Suchowersky Oksana; Klein Christine; Golbe Lawrence I; Mark Margery H; Growdon John H; Wooten G Frederick; Watts Ray L; Guttman Mark; Racette Brad A; Perlmutter Joel S; Ahmed Anwar; Shill Holly A; Singer Carlos; Saint-Hilaire Marie H; Massood Tiffany; Huskey Karen W; DeStefano Anita L; Gillis Tammy; Mysore Jayalakshmi; Goldwurm Stefano; Pezzoli Gianni; Baker Kenneth B; Itin Ilia; Litvan Irene; Nicholson Garth; Corbett Alastair; Nance Martha; Drasby Edward; Isaacson Stuart; Burn David J; Chinnery Patrick F; Pramstaller Peter P; Al-Hinti Jomana; Moller Anette T; Ostergaard Karen; Sherman Scott J; Roxburgh Richard; Snow Barry; Slevin John T; Cambi Franca; Gusella James F; Myers Richard H
Huntington CAG repeat size does not modify onset age in familial Parkinson's disease: the GenePD study.
Movement disorders : official journal of the Movement Disorder Society 2008;23(11):1596-601.
2008: DeStefano Anita L; Latourelle Jeanne; Lew Mark F; Suchowersky Oksana; Klein Christine; Golbe Lawrence I; Mark Margery H; Growdon John H; Wooten G Fredrick; Watts Ray; Guttman Mark; Racette Brad A; Perlmutter Joel S; Marlor Lynn; Shill Holly A; Singer Carlos; Goldwurm Stefano; Pezzoli Gianni; Saint-Hilaire Marie H; Hendricks Audrey E; Gower Adam; Williamson Sally; Nagle Michael W; Wilk Jemma B; Massood Tiffany; Huskey Karen W; Baker Kenneth B; Itin Ilia; Litvan Irene; Nicholson Garth; Corbett Alastair; Nance Martha; Drasby Edward; Isaacson Stuart; Burn David J; Chinnery Patrick F; Pramstaller Peter P; Al-Hinti Jomana; Moller Anette T; Ostergaard Karen; Sherman Scott J; Roxburgh Richard; Snow Barry; Slevin John T; Cambi Franca; Gusella James F; Myers Richard H
Replication of association between ELAVL4 and Parkinson disease: the GenePD study.
Human genetics 2008;124(1):95-9.
2008: Facheris Maurizio Francesco; Maniak Susanna; Scaravilli Francesco; Schüle Birgit; Klein Christine; Pramstaller Peter Paul
Pure akinesia as initial presentation of PSP: a clinicopathological study.
Parkinsonism & related disorders 2008;14(6):517-9.
2008: Reetz Kathrin; Lencer Rebekka; Steinlechner Susanne; Gaser Christian; Hagenah Johann; Büchel Christian; Petersen Dirk; Kock Norman; Djarmati Ana; Siebner Hartwig R; Klein Christine; Binkofski Ferdinand
Limbic and frontal cortical degeneration is associated with psychiatric symptoms in PINK1 mutation carriers.
Biological psychiatry 2008;64(3):241-7.
2008: Healy Daniel G; Falchi Mario; O'Sullivan Sean S; Bonifati Vincenzo; Durr Alexandra; Bressman Susan; Brice Alexis; Aasly Jan; Zabetian Cyrus P; Goldwurm Stefano; Ferreira Joaquim J; Tolosa Eduardo; Kay Denise M; Klein Christine; Williams David R; Marras Connie; Lang Anthony E; Wszolek Zbigniew K; Berciano Jose; Schapira Anthony H V; Lynch Timothy; Bhatia Kailash P; Gasser Thomas; Lees Andrew J; Wood Nicholas W;
Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study.
Lancet neurology 2008;7(7):583-90.
2008: Tobin J E; Latourelle J C; Lew M F; Klein C; Suchowersky O; Shill H A; Golbe L I; Mark M H; Growdon J H; Wooten G F; Racette B A; Perlmutter J S; Watts R; Guttman M; Baker K B; Goldwurm S; Pezzoli G; Singer C; Saint-Hilaire M H; Hendricks A E; Williamson S; Nagle M W; Wilk J B; Massood T; Laramie J M; DeStefano A L; Litvan I; Nicholson G; Corbett A; Isaacson S; Burn D J; Chinnery P F; Pramstaller P P; Sherman S; Al-hinti J; Drasby E; Nance M; Moller A T; Ostergaard K; Roxburgh R; Snow B; Slevin J T; Cambi F; Gusella J F; Myers R H
Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study.
Neurology 2008;71(1):28-34.
2008: Kamm C; Fischer H; Garavaglia B; Kullmann S; Sharma M; Schrader C; Grundmann K; Klein C; Borggraefe I; Lobsien E; Kupsch A; Nardocci N; Gasser T
Susceptibility to DYT1 dystonia in European patients is modified by the D216H polymorphism.
Neurology 2008;70(23):2261-2.
2008: Muhle Hiltrud; Neumann Anja; Lohmann-Hedrich Katja; Lohnau Thora; Lu Yang; Winkler Susen; Waltz Stephan; Fischenbeck Anke; Kramer Patricia L; Klein Christine; Stephani Ulrich
Childhood-onset restless legs syndrome: clinical and genetic features of 22 families.
Movement disorders : official journal of the Movement Disorder Society 2008;23(8):1113-21; quiz 1203.
2008: Seibler Philip; Djarmati Ana; Langpap Brigitte; Hagenah Johann; Schmidt Alexander; Brüggemann Norbert; Siebner Hartwig; Jabusch Hans-Christian; Altenmüller Eckart; Münchau Alexander; Lohmann Katja; Klein Christine
A heterozygous frameshift mutation in PRKRA (DYT16) associated with generalised dystonia in a German patient.
Lancet neurology 2008;7(5):380-1.
2008: Klein Christine; Ziegler Andreas
How to predict the risk of Parkinson disease in relatives of parkin mutation carriers: a complex puzzle of age, penetrance, and number of mutated alleles.
Archives of neurology 2008;65(4):443-4.
2008: Moro E; Volkmann J; König I R; Winkler S; Hiller A; Hassin-Baer S; Herzog J; Schnitzler A; Lohmann K; Pinsker M O; Voges J; Djarmatic A; Seibler P; Lozano A M; Rogaeva E; Lang A E; Deuschl G; Klein C
Bilateral subthalamic stimulation in Parkin and PINK1 parkinsonism.
Neurology 2008;70(14):1186-91.
2008: Haugarvoll K; Rademakers R; Kachergus J M; Nuytemans K; Ross O A; Gibson J M; Tan E-K; Gaig C; Tolosa E; Goldwurm S; Guidi M; Riboldazzi G; Brown L; Walter U; Benecke R; Berg D; Gasser T; Theuns J; Pals P; Cras P; De Deyn P Paul; Engelborghs S; Pickut B; Uitti R J; Foroud T; Nichols W C; Hagenah J; Klein C; Samii A; Zabetian C P; Bonifati V; Van Broeckhoven C; Farrer M J; Wszolek Z K
Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease.
Neurology 2008;70(16 Pt 2):1456-60.
2008: Klein Christine
DYT16: a new twist to familial dystonia.
Lancet neurology 2008;7(3):192-3.
2008: Raymond Deborah; Saunders-Pullman Rachel; de Carvalho Aguiar Patricia; Schule Birgitt; Kock Norman; Friedman Jennifer; Harris Juliette; Ford Blair; Frucht Steven; Heiman Gary A; Jennings Danna; Doheny Dana; Brin Mitchell F; de Leon Brin Deborah; Multhaupt-Buell Trisha; Lang Anthony E; Kurlan Roger; Klein Christine; Ozelius Laurie; Bressman Susan
Phenotypic spectrum and sex effects in eleven myoclonus-dystonia families with epsilon-sarcoglycan mutations.
Movement disorders : official journal of the Movement Disorder Society 2008;23(4):588-92.
2008: Paus Sebastian; Grünewald Anne; Klein Christine; Knapp Michael; Zimprich Alexander; Janetzky Bernd; Möller Jens C; Klockgether Thomas; Wüllner Ullrich
The DRD2 TaqIA polymorphism and demand of dopaminergic medication in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2008;23(4):599-602.
2008: Grünewald A; Djarmati A; Lohmann-Hedrich K; Farrell K; Zeller J A; Allert N; Papengut F; Petersen B; Fung V; Sue C M; O'Sullivan D; Mahant N; Kupsch A; Chuang R S; Wiegers K; Pawlack H; Hagenah J; Ozelius L J; Stephani U; Schuit R; Lang A E; Volkmann J; Münchau A; Klein C
Myoclonus-dystonia: significance of large SGCE deletions.
Human mutation 2008;29(2):331-2.
2008: Lohmann-Hedrich K; Neumann A; Kleensang A; Lohnau T; Muhle H; Djarmati A; König I R; Pramstaller P P; Schwinger E; Kramer P L; Ziegler A; Stephani U; Klein C
Evidence for linkage of restless legs syndrome to chromosome 9p: are there two distinct loci?
Neurology 2008;70(9):686-94.
2008: Reetz K; Siebner H R; Gaser C; Hagenah J; Buechel C; Kasten M; Petersen D; Pramstaller P P; Klein C; Binkofksi F
Premotor Gray Matter Volume is Associated with Clinical Findings in Idiopathic and Genetically Determined Parkinson's Disease.
The open neuroimaging journal 2008;2():102-5.
2008: Latourelle Jeanne C; Sun Mei; Lew Mark F; Suchowersky Oksana; Klein Christine; Golbe Lawrence I; Mark Margery H; Growdon John H; Wooten G Frederick; Watts Ray L; Guttman Mark; Racette Brad A; Perlmutter Joel S; Ahmed Anwar; Shill Holly A; Singer Carlos; Goldwurm Stefano; Pezzoli Gianni; Zini Michela; Saint-Hilaire Marie H; Hendricks Audrey E; Williamson Sally; Nagle Michael W; Wilk Jemma B; Massood Tiffany; Huskey Karen W; Laramie Jason M; DeStefano Anita L; Baker Kenneth B; Itin Ilia; Litvan Irene; Nicholson Garth; Corbett Alastair; Nance Martha; Drasby Edward; Isaacson Stuart; Burn David J; Chinnery Patrick F; Pramstaller Peter P; Al-hinti Jomana; Moller Anette T; Ostergaard Karen; Sherman Scott J; Roxburgh Richard; Snow Barry; Slevin John T; Cambi Franca; Gusella James F; Myers Richard H
The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study.
BMC medicine 2008;6():32.
2007: Djarmati A; Dobricic V; Kecmanovic M; Marsh P; Jancic-Stefanovic J; Klein C; Djuric M; Romac S
MECP2 mutations in Serbian Rett syndrome patients.
Acta neurologica Scandinavica 2007;116(6):413-9.
2007: Petrovic Igor; Klein Christine; Kostic Vladimir S
Delayed-onset dystonia due to perinatal asphyxia: a prospective study.
Movement disorders : official journal of the Movement Disorder Society 2007;22(16):2426-9.
2007: Bäumer T; Pramstaller P P; Siebner H R; Schippling S; Hagenah J; Peller M; Gerloff C; Klein C; Münchau A
Sensorimotor integration is abnormal in asymptomatic Parkin mutation carriers: a TMS study.
Neurology 2007;69(21):1976-81.
2007: Klein Christine; Schlossmacher Michael G
Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder.
Neurology 2007;69(22):2093-104.
2007: Winkler Susan; König Inke R; Lohmann-Hedrich Katja; Vieregge Peter; Kostic Vladimir; Klein Christine
Role of ethnicity on the association of MAPT H1 haplotypes and subhaplotypes in Parkinson's disease.
European journal of human genetics : EJHG 2007;15(11):1163-8.
2007: Hagenah J M; König I R; Becker B; Hilker R; Kasten M; Hedrich K; Pramstaller P P; Klein C; Seidel G
Substantia nigra hyperechogenicity correlates with clinical status and number of Parkin mutated alleles.
Journal of neurology 2007;254(10):1407-13.
2007: Winkler S; Hagenah J; Lincoln S; Heckman M; Haugarvoll K; Lohmann-Hedrich K; Kostic V; Farrer M; Klein C
alpha-Synuclein and Parkinson disease susceptibility.
Neurology 2007;69(18):1745-50.
2007: Orth Michael; Djarmati Ana; Bäumer Tobias; Winkler Susan; Grünewald Anne; Lohmann-Hedrich Katja; Kabakci Kemal; Hagenah Johann; Klein Christine; Münchau Alexander
Autosomal dominant myoclonus-dystonia and Tourette syndrome in a family without linkage to the SGCE gene.
Movement disorders : official journal of the Movement Disorder Society 2007;22(14):2090-6.
2007: Hübner J; Sprenger A; Klein C; Hagenah J; Rambold H; Zühlke C; Kömpf D; Rolfs A; Kimmig H; Helmchen C
Eye movement abnormalities in spinocerebellar ataxia type 17 (SCA17).
Neurology 2007;69(11):1160-8.
2007: Djarmati Ana; Guzvic Miodrag; Grünewald Anne; Lang Anthony E; Pramstaller Peter P; Simon David K; Kaindl Angela M; Vieregge Peter; Nygren Anders O H; Beetz Christian; Hedrich Katja; Klein Christine
Rapid and reliable detection of exon rearrangements in various movement disorders genes by multiplex ligation-dependent probe amplification.
Movement disorders : official journal of the Movement Disorder Society 2007;22(12):1708-14.
2007: Binkofski F; Reetz K; Gaser C; Hilker R; Hagenah J; Hedrich K; van Eimeren T; Thiel A; Büchel C; Pramstaller P P; Siebner H R; Klein C
Morphometric fingerprint of asymptomatic Parkin and PINK1 mutation carriers in the basal ganglia.
Neurology 2007;69(9):842-50.
2007: Klein Christine; Lohmann-Hedrich Katja
Impact of recent genetic findings in Parkinson's disease.
Current opinion in neurology 2007;20(4):453-64.
2007: Klein Christine; Bonifati Vincenzo
Dissecting the complexity of frontotemporal dementia: genotypes, phenotypes, and phenocopies.
Neurology 2007;69(2):129-30.
2007: Klein Christine; Lohmann-Hedrich Katja; Rogaeva Ekaterina; Schlossmacher Michael G; Lang Anthony E
Deciphering the role of heterozygous mutations in genes associated with parkinsonism.
Lancet neurology 2007;6(7):652-62.
2007: Hagenah J; Reetz K; Zühlke C; Rolfs A; Binkofski F; Klein C
Predominant dystonia with marked cerebellar atrophy: a rare phenotype in familial dystonia.
Neurology 2007;68(24):2157; author reply 2157-8.
2007: Clark Lorraine N; Haamer Eneli; Mejia-Santana Helen; Harris Juliette; Lesage Suzanne; Durr Alexandra; Bs Sabine Janin; Hedrich Katja; Louis Elan D; Cote Lucien J; Andrews Howard; Fahn Stanley; Waters Cheryl; Ford Blair; Frucht Steven; Scott William; Klein Christine; Brice Alexis; Roomere Hanno; Ottman Ruth; Marder Karen
Construction and validation of a Parkinson's disease mutation genotyping array for the Parkin gene.
Movement disorders : official journal of the Movement Disorder Society 2007;22(7):932-7.
2007: Steinlechner Susanne; Stahlberg Jessica; Völkel Birgit; Djarmati Ana; Hagenah Johann; Hiller Anja; Hedrich Katja; König Inke; Klein Christine; Lencer Rebekka
Co-occurrence of affective and schizophrenia spectrum disorders with PINK1 mutations.
Journal of neurology, neurosurgery, and psychiatry 2007;78(5):532-5.
2007: Janzarik W G; Kratz C P; Loges N T; Olbrich H; Klein C; Schäfer T; Scheurlen W; Roggendorf W; Weiller C; Niemeyer C; Korinthenberg R; Pfister S; Omran H
Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma.
Neuropediatrics 2007;38(2):61-3.
2007: Eggert Karla; Wüllner Ullrich; Antony Gisela; Gasser Thomas; Janetzky Bernd; Klein Christine; Schöls Ludger; Oertel Wolfgang
Data protection in biomaterial banks for Parkinson's disease research: the model of GEPARD (Gene Bank Parkinson's Disease Germany).
Movement disorders : official journal of the Movement Disorder Society 2007;22(5):611-8.
2007: Grünewald Anne; Breedveld Guido J; Lohmann-Hedrich Katja; Rohé Christan F; König Inke R; Hagenah Johann; Vanacore Nicola; Meco Giuseppe; Antonini Angelo; Goldwurm Stefano; Lesage Suzanne; Dürr Alexandra; Binkofski Ferdinand; Siebner Hartwig; Münchau Alexander; Brice Alexis; Oostra Ben A; Klein Christine; Bonifati Vincenzo
Biological effects of the PINK1 c.1366C>T mutation: implications in Parkinson disease pathogenesis.
Neurogenetics 2007;8(2):103-9.
2007: Brashear Allison; Dobyns William B; de Carvalho Aguiar Patricia; Borg Michel; Frijns C J M; Gollamudi Seema; Green Andrew; Guimaraes João; Haake Bret C; Klein Christine; Linazasoro Gurutz; Münchau Alexander; Raymond Deborah; Riley David; Saunders-Pullman Rachel; Tijssen Marina A J; Webb David; Zaremba Jacek; Bressman Susan B; Ozelius Laurie J
The phenotypic spectrum of rapid-onset dystonia-parkinsonism (RDP) and mutations in the ATP1A3 gene.
Brain : a journal of neurology 2007;130(Pt 3):828-35.
2007: Hess C W; Raymond D; Aguiar P de Carvalho; Frucht S; Shriberg J; Heiman G A; Kurlan R; Klein C; Bressman S B; Ozelius L J; Saunders-Pullman R
Myoclonus-dystonia, obsessive-compulsive disorder, and alcohol dependence in SGCE mutation carriers.
Neurology 2007;68(7):522-4.
2007: Kemlink David; Polo Olli; Montagna Pasquale; Provini Federica; Stiasny-Kolster Karin; Oertel Wolfgang; de Weerd Al; Nevsimalova Sona; Sonka Karel; Högl Birgit; Frauscher Birgit; Poewe Werner; Trenkwalder Claudia; Pramstaller Peter P; Ferini-Strambi Luigi; Zucconi Marco; Konofal Eric; Arnulf Isabelle; Hadjigeorgiou Georgios M; Happe Svenja; Klein Christine; Hiller Anja; Lichtner Peter; Meitinger Thomas; Müller-Myshok Betram; Winkelmann Juliane
Family-based association study of the restless legs syndrome loci 2 and 3 in a European population.
Movement disorders : official journal of the Movement Disorder Society 2007;22(2):207-12.
2007: Hiller Anja; Hagenah Johann M; Djarmati Ana; Hedrich Katja; Reetz Kathrin; Schneider-Gold Christiane; Kress Wolfgang; Münchau Alexander; Klein Christine
Phenotypic spectrum of PINK1-associated parkinsonism in 15 mutation carriers from 1 family.
Movement disorders : official journal of the Movement Disorder Society 2007;22(1):145-7.
2007: Winkelmann Juliane; Polo Oli; Provini Federica; Nevsimalova Sonja; Kemlink David; Sonka Karel; Högl Birgit; Poewe Werner; Stiasny-Kolster Karin; Oertel Wolfgang; de Weerd Al; Strambi Luigi Ferini; Zucconi Marco; Pramstaller Peter P; Arnulf Isabelle; Trenkwalder Claudia; Klein Christine; Hadjigeorgiou Georgios M; Happe Svenja; Rye David; Montagna Pasquale
Genetics of restless legs syndrome (RLS): State-of-the-art and future directions.
Movement disorders : official journal of the Movement Disorder Society 2007;22 Suppl 18():S449-58.
2007: Trenkwalder Claudia; Kohnen Ralf; Allen Richard P; Benes Heike; Ferini-Strambi Luigi; Garcia-Borreguero Diego; Hadjigeorgiou Georgios M; Happe Svenja; Högl Birgit; Hornyak Magdolna; Klein Christine; Nass Alexander; Montagna Pasquale; Oertel Wolfgang H; O'Keeffe Shaun; Paulus Walter; Poewe Werner; Provini Federica; Pramstaller Peter P; Sieminski Mariusz; Sonka Karel; Stiasny-Kolster Karin; de Weerd Al; Wetter Thomas C; Winkelmann Juliane; Zucconi Marco
Clinical trials in restless legs syndrome--recommendations of the European RLS Study Group (EURLSSG).
Movement disorders : official journal of the Movement Disorder Society 2007;22 Suppl 18():S495-504.
2006: Wilk J B; Tobin J E; Suchowersky O; Shill H A; Klein C; Wooten G F; Lew M F; Mark M H; Guttman M; Watts R L; Singer C; Growdon J H; Latourelle J C; Saint-Hilaire M H; DeStefano A L; Prakash R; Williamson S; Berg C J; Sun M; Goldwurm S; Pezzoli G; Racette B A; Perlmutter J S; Parsian A; Baker K B; Giroux M L; Litvan I; Pramstaller P P; Nicholson G; Burn D J; Chinnery P F; Vieregge P; Slevin J T; Cambi F; MacDonald M E; Gusella J F; Myers R H; Golbe L I
Herbicide exposure modifies GSTP1 haplotype association to Parkinson onset age: the GenePD Study.
Neurology 2006;67(12):2206-10.
2006: Kostic Vladimir S; Svetel Marina; Kabakci Kemal; Ristic Aleksandar; Petrovic Igor; Schüle Birgitt; Kock Norman; Djarmati Ana; Romac Stanka; Klein Christine
Intrafamilial phenotypic and genetic heterogeneity of dystonia.
Journal of the neurological sciences 2006;250(1-2):92-6.
2006: Foncke E M J; Gerrits M C F; van Ruissen F; Baas F; Hedrich K; Tijssen C C; Klein C; Tijssen M A J
Distal myoclonus and late onset in a large Dutch family with myoclonus-dystonia.
Neurology 2006;67(9):1677-80.
2006: Stefanova Elka; Djarmati Ana; Momcilovic Dragana; Dragasevic Natasa; Svetel Marina; Klein Christine; Kostic Vladimir S
Clinical characteristics of paroxysmal nonkinesigenic dyskinesia in Serbian family with Myofibrillogenesis regulator 1 gene mutation.
Movement disorders : official journal of the Movement Disorder Society 2006;21(11):2010-5.
2006: Pichler Irene; Marroni Fabio; Volpato Claudia Beu; Gusella James F; Klein Christine; Casari Giorgio; De Grandi Alessandro; Pramstaller Peter P
Linkage analysis identifies a novel locus for restless legs syndrome on chromosome 2q in a South Tyrolean population isolate.
American journal of human genetics 2006;79(4):716-23.
2006: Lasek K; Lencer R; Gaser C; Hagenah J; Walter U; Wolters A; Kock N; Steinlechner S; Nagel M; Zühlke C; Nitschke M-F; Brockmann K; Klein C; Rolfs A; Binkofski F
Morphological basis for the spectrum of clinical deficits in spinocerebellar ataxia 17 (SCA17).
Brain : a journal of neurology 2006;129(Pt 9):2341-52.
2006: Hedrich Katja; Winkler Susen; Hagenah Johann; Kabakci Kemal; Kasten Meike; Schwinger Eberhard; Volkmann Jens; Pramstaller Peter P; Kostic Vladimir; Vieregge Peter; Klein Christine
Recurrent LRRK2 (Park8) mutations in early-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2006;21(9):1506-10.
2006: Djarmati Ana; Hedrich Katja; Svetel Marina; Lohnau Thora; Schwinger Eberhard; Romac Stanka; Pramstaller Peter P; Kostic Vladimir; Klein Christine
Heterozygous PINK1 mutations: a susceptibility factor for Parkinson disease?
Movement disorders : official journal of the Movement Disorder Society 2006;21(9):1526-30.
2006: Schmidt A; Jabusch H-C; Altenmüller E; Hagenah J; Brüggemann N; Hedrich K; Saunders-Pullman R; Bressman S B; Kramer P L; Klein C
Dominantly transmitted focal dystonia in families of patients with musician's cramp.
Neurology 2006;67(4):691-3.
2006: Helmchen C; Schwekendiek A; Pramstaller P P; Hedrich K; Klein C; Rambold H
Blink amplitude but not saccadic hypometria indicates carriers of Parkin mutations.
Journal of neurology 2006;253(8):1071-5.
2006: Vogl Florian D; Pichler Irene; Adel Susanna; Pinggera Gerd K; Bracco Stefano; De Grandi Alessandro; Volpato Claudia Beu; Aridon Paolo; Mayer Thomas; Meitinger Thomas; Klein Christine; Casari Giorgio; Pramstaller Peter P
Restless legs syndrome: epidemiological and clinicogenetic study in a South Tyrolean population isolate.
Movement disorders : official journal of the Movement Disorder Society 2006;21(8):1189-95.
2006: Hagenah J M; Hedrich K; Becker B; Pramstaller P P; Seidel G; Klein C
Distinguishing early-onset PD from dopa-responsive dystonia with transcranial sonography.
Neurology 2006;66(12):1951-2.
2006: Hedrich Katja; Hagenah Johann; Djarmati Ana; Hiller Anja; Lohnau Thora; Lasek Kathrin; Grünewald Anne; Hilker Rüdiger; Steinlechner Susanne; Boston Heather; Kock Norman; Schneider-Gold Christiane; Kress Wolfram; Siebner Hartwig; Binkofski Ferdinand; Lencer Rebekka; Münchau Alexander; Klein Christine
Clinical spectrum of homozygous and heterozygous PINK1 mutations in a large German family with Parkinson disease: role of a single hit?
Archives of neurology 2006;63(6):833-8.
2006: Sun Mei; Latourelle Jeanne C; Wooten G Frederick; Lew Mark F; Klein Christine; Shill Holly A; Golbe Lawrence I; Mark Margery H; Racette Brad A; Perlmutter Joel S; Parsian Abbas; Guttman Mark; Nicholson Garth; Xu Gang; Wilk Jemma B; Saint-Hilaire Marie H; DeStefano Anita L; Prakash Ranjana; Williamson Sally; Suchowersky Oksana; Labelle Nancy; Growdon John H; Singer Carlos; Watts Ray L; Goldwurm Stefano; Pezzoli Gianni; Baker Kenneth B; Pramstaller Peter P; Burn David J; Chinnery Patrick F; Sherman Scott; Vieregge Peter; Litvan Irene; Gillis Tammy; MacDonald Marcy E; Myers Richard H; Gusella James F
Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study.
Archives of neurology 2006;63(6):826-32.
2006: Zadikoff Cindy; Rogaeva Ekaterina; Djarmati Ana; Sato Christine; Salehi-Rad Shabnam; St George-Hyslop Peter; Klein Christine; Lang Anthony E
Homozygous and heterozygous PINK1 mutations: considerations for diagnosis and care of Parkinson's disease patients.
Movement disorders : official journal of the Movement Disorder Society 2006;21(6):875-9.
2006: Nitschke M F; Erdmann C; Trillenberg P; Sprenger A; Kock N; Sperner J; Klein C
Functional MRI reveals activation of a subcortical network in a 5-year-old girl with genetically confirmed myoclonus-dystonia.
Neuropediatrics 2006;37(2):79-82.
2006: Klein Christine; Grünewald Anne; Hedrich Katja
Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes.
Neurology 2006;66(7):1129-30; author reply 1129-30.
2006: Klein Christine; Schlossmacher Michael G
The genetics of Parkinson disease: Implications for neurological care.
Nature clinical practice. Neurology 2006;2(3):136-46.
2006: Gerrits M C F; Foncke E M J; de Haan R; Hedrich K; van de Leemput Y L C; Baas F; Ozelius L J; Speelman J D; Klein C; Tijssen M A J
Phenotype-genotype correlation in Dutch patients with myoclonus-dystonia.
Neurology 2006;66(5):759-61.
2006: Klein Christine
Implications of genetics on the diagnosis and care of patients with Parkinson disease.
Archives of neurology 2006;63(3):328-34.
2006: Adel Susanna; Djarmati Ana; Kabakci Kemal; Pichler Irene; Eskelson Cordula; Lohnau Thora; Kock Norman; Hagenah Johann; Hedrich Katja; Schwinger Eberhard; Kramer Patricia L; Pramstaller Peter P; Klein Christine
Co-occurrence of restless legs syndrome and Parkin mutations in two families.
Movement disorders : official journal of the Movement Disorder Society 2006;21(2):258-63.
2006: Dragasevic Natasa T; Culjkovic Biljana; Klein Christine; Ristic Aleksandar; Keckarevic Milica; Topisirovic Ivan; Vukosavic Slobodanka; Svetel Marina; Kock Norman; Stefanova Elka; Romac Stanka; Kostic Vladimir S
Frequency analysis and clinical characterization of different types of spinocerebellar ataxia in Serbian patients.
Movement disorders : official journal of the Movement Disorder Society 2006;21(2):187-91.
2006: Ozelius Laurie J; Senthil Geetha; Saunders-Pullman Rachel; Ohmann Erin; Deligtisch Amanda; Tagliati Michele; Hunt Ann L; Klein Christine; Henick Brian; Hailpern Susan M; Lipton Richard B; Soto-Valencia Jeannie; Risch Neil; Bressman Susan B
LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews.
The New England journal of medicine 2006;354(4):424-5.
2005: Karamohamed S; Latourelle J C; Racette B A; Perlmutter J S; Wooten G F; Lew M; Klein C; Shill H; Golbe L I; Mark M H; Guttman M; Nicholson G; Wilk J B; Saint-Hilaire M; DeStefano A L; Prakash R; Tobin S; Williamson J; Suchowersky O; Labell N; Growdon B N J; Singer C; Watts R; Goldwurm S; Pezzoli G; Baker K B; Giroux M L; Pramstaller P P; Burn D J; Chinnery P; Sherman S; Vieregge P; Litvan I; Gusella J F; Myers R H; Parsian A
BDNF genetic variants are associated with onset age of familial Parkinson disease: GenePD Study.
Neurology 2005;65(11):1823-5.
2005: Djarmati Ana; Svetel Marina; Momcilovic Dragana; Kostic Vladimir; Klein Christine
Significance of recurrent mutations in the myofibrillogenesis regulator 1 gene.
Archives of neurology 2005;62(10):1641.
2005: Buhmann C; Binkofski F; Klein C; Büchel C; van Eimeren T; Erdmann C; Hedrich K; Kasten M; Hagenah J; Deuschl G; Pramstaller P P; Siebner H R
Motor reorganization in asymptomatic carriers of a single mutant Parkin allele: a human model for presymptomatic parkinsonism.
Brain : a journal of neurology 2005;128(Pt 10):2281-90.
2005: Kis B; Hedrich K; Kann M; Schwinger E; Kömpf D; Klein C; Pramstaller P P
Oculogyric dystonic states in early-onset parkinsonism with basal ganglia calcifications.
Neurology 2005;65(5):761.
2005: Pramstaller Peter P; Schlossmacher Michael G; Jacques Thomas S; Scaravilli Francesco; Eskelson Cordula; Pepivani Imelda; Hedrich Katja; Adel Susanna; Gonzales-McNeal Melissa; Hilker Rüdiger; Kramer Patricia L; Klein Christine
Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers.
Annals of neurology 2005;58(3):411-22.
2005: Klein Christine; Djarmati Ana; Hedrich Katja; Schäfer Nora; Scaglione Cesa; Marchese Roberta; Kock Norman; Schüle Birgitt; Hiller Anja; Lohnau Thora; Winkler Susen; Wiegers Karin; Hering Robert; Bauer Peter; Riess Olaf; Abbruzzese Giovanni; Martinelli Paolo; Pramstaller Peter P
PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism.
European journal of human genetics : EJHG 2005;13(9):1086-93.
2005: Karamohamed Samer; Golbe L I; Mark M H; Lazzarini A M; Suchowersky O; Labelle N; Guttman Mark; Currie L J; Wooten G F; Stacy M; Saint-Hilaire M; Feldman R G; Liu J; Shoemaker C M; Wilk J B; DeStefano A L; Latourelle J C; Xu G; Watts R; Growdon J; Lew M; Waters C; Vieregge P; Pramstaller P P; Klein C; Racette B A; Perlmutter J S; Parsian A; Singer Carlos; Montgomery E; Baker K; Gusella J F; Herbert A; Myers R H
Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson's disease from the GenePD study.
Movement disorders : official journal of the Movement Disorder Society 2005;20(9):1188-91.
2005: Berg Daniela; Niwar Marc; Maass Sylvia; Zimprich Alexander; Möller J Carsten; Wuellner Ullrich; Schmitz-Hübsch Tanja; Klein Christine; Tan Eng-King; Schöls Ludger; Marsh Laura; Dawson Ted M; Janetzky Bernd; Müller Thomas; Woitalla Dirk; Kostic Vladimir; Pramstaller Peter P; Oertel Wolfgang H; Bauer Peter; Krueger Rejko; Gasser Thomas; Riess Olaf
Alpha-synuclein and Parkinson's disease: implications from the screening of more than 1,900 patients.
Movement disorders : official journal of the Movement Disorder Society 2005;20(9):1191-4.
2005: Hedrich Katja; Pramstaller Peter P; Stübke Katrin; Hiller Anja; Kabakci Kemal; Purmann Sabine; Kasten Meike; Scaglione Cesa; Schwinger Eberhard; Volkmann Jens; Kostic Vladimir; Vieregge Peter; Martinelli Paolo; Abbruzzese Giovanni; Klein Christine; Zühlke Christine
Premutations in the FMR1 gene as a modifying factor in Parkin-associated Parkinson's disease?
Movement disorders : official journal of the Movement Disorder Society 2005;20(8):1060-2.
2005: Kabakci K; Isbruch K; Schilling K; Hedrich K; de Carvalho Aguiar P; Ozelius L J; Kramer P L; Schwarz M H R M; Klein C
Genetic heterogeneity in rapid onset dystonia-parkinsonism: description of a new family.
Journal of neurology, neurosurgery, and psychiatry 2005;76(6):860-2.
2005: Hagenah J; Kahl K G; Steinlechner S; Lencer R; Klein C
[Treatment of sialorrhea with botulinum toxin: an overview]
Der Nervenarzt 2005;76(4):418-25.
2005: Hagenah J; Saunders-Pullman R; Hedrich K; Kabakci K; Habermann K; Wiegers K; Mohrmann K; Lohnau T; Raymond D; Vieregge P; Nygaard T; Ozelius L J; Bressman S B; Klein C
High mutation rate in dopa-responsive dystonia: detection with comprehensive GCHI screening.
Neurology 2005;64(5):908-11.
2005: Kahl K G; Trillenberg P; Kordon A; Lencer R; Klein C; Hagenah J
[Pharmacological strategies for clozapine-induced hypersalivation: treatment with botulinum toxin B in one patient and review of the literature]
Der Nervenarzt 2005;76(2):205-8.
2005: Klein C
Movement disorders: classifications.
Journal of inherited metabolic disease 2005;28(3):425-39.
2004: Lencer Rebekka; Eismann Gunnar; Kasten Meike; Kabakci Kemal; Geithe Verena; Grimm Jenny; Klein Christine
Family history of primary movement disorders as a predictor for neuroleptic-induced extrapyramidal symptoms.
The British journal of psychiatry : the journal of mental science 2004;185():465-71.
2004: Walter Uwe; Klein Christine; Hilker Ruediger; Benecke Reiner; Pramstaller Peter P; Dressler Dirk
Brain parenchyma sonography detects preclinical parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2004;19(12):1445-9.
2004: Saunders-Pullman R; Blau N; Hyland K; Zschocke J; Nygaard T; Raymond D; Shanker V; Mohrmann K; Arnold L; Tabbal S; deLeon D; Ford B; Brin M; Chouinard S; Ozelius L; Klein C; Bressman S B
Phenylalanine loading as a diagnostic test for DRD: interpreting the utility of the test.
Molecular genetics and metabolism 2004;83(3):207-12.
2004: Hedrich Katja; Eskelson Cordula; Wilmot Beth; Marder Karen; Harris Juliette; Garrels Jennifer; Meija-Santana Helen; Vieregge Peter; Jacobs Helfried; Bressman Susan B; Lang Anthony E; Kann Martin; Abbruzzese Giovanni; Martinelli Paolo; Schwinger Eberhard; Ozelius Laurie J; Pramstaller Peter P; Klein Christine; Kramer Patricia
Distribution, type, and origin of Parkin mutations: review and case studies.
Movement disorders : official journal of the Movement Disorder Society 2004;19(10):1146-57.
2004: Hering Robert; Strauss Karsten M; Tao Xiao; Bauer Andreas; Woitalla Dirk; Mietz Eva-Maria; Petrovic Slobodanka; Bauer Peter; Schaible Wilhelm; Müller Thomas; Schöls Ludger; Klein Christine; Berg Daniela; Meyer Philipp T; Schulz Jörg B; Wollnik Bernd; Tong Liang; Krüger Rejko; Riess Olaf
Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7).
Human mutation 2004;24(4):321-9.
2004: Schüle B; Kock N; Svetel M; Dragasevic N; Hedrich K; De Carvalho Aguiar P; Liu L; Kabakci K; Garrels J; Meyer E-M; Berisavac I; Schwinger E; Kramer P L; Ozelius L J; Klein C; Kostic V
Genetic heterogeneity in ten families with myoclonus-dystonia.
Journal of neurology, neurosurgery, and psychiatry 2004;75(8):1181-5.
2004: Wang Fang; Denison Stacy; Lai Jin-Ping; Philips Leslie A; Montoya Damien; Kock Norman; Schüle Birgitt; Klein Christine; Shridhar Viji; Roberts Lewis R; Smith David I
Parkin gene alterations in hepatocellular carcinoma.
Genes, chromosomes & cancer 2004;40(2):85-96.
2004: Djarmati Ana; Hedrich Katja; Svetel Marina; Schäfer Nora; Juric Vladislava; Vukosavic Slobodanka; Hering Robert; Riess Olaf; Romac Stanka; Klein Christine; Kostic Vladimir
Detection of Parkin (PARK2) and DJ1 (PARK7) mutations in early-onset Parkinson disease: Parkin mutation frequency depends on ethnic origin of patients.
Human mutation 2004;23(5):525.
2004: Klein Christine
[Genetics of dystonia]
Fortschritte der Neurologie-Psychiatrie 2004;72(4):220-32; quiz 233-4.
2004: Hedrich K; Meyer E-M; Schüle B; Kock N; de Carvalho Aguiar P; Wiegers K; Koelman J H; Garrels J; Dürr R; Liu L; Schwinger E; Ozelius L J; Landwehrmeyer B; Stoessl A J; Tijssen M A J; Klein C
Myoclonus-dystonia: detection of novel, recurrent, and de novo SGCE mutations.
Neurology 2004;62(7):1229-31.
2004: Kahl Kai G; Hagenah Johann; Zapf Silke; Trillenberg Peter; Klein Christine; Lencer Rebekka
Botulinum toxin as an effective treatment of clozapine-induced hypersalivation.
Psychopharmacology 2004;173(1-2):229-30.
2004: Kock Norman; Kasten Meike; Schüle Birgitt; Hedrich Katja; Wiegers Karin; Kabakci Kemal; Hagenah Johann; Pramstaller Peter P; Nitschke Matthias F; Münchau Alexander; Sperner Jürgen; Klein Christine
Clinical and genetic features of myoclonus-dystonia in 3 cases: a video presentation.
Movement disorders : official journal of the Movement Disorder Society 2004;19(2):231-4.
2004: Hagenah Johann M; Zühlke Christine; Hellenbroich Yorck; Heide Wolfgang; Klein Christine
Focal dystonia as a presenting sign of spinocerebellar ataxia 17.
Movement disorders : official journal of the Movement Disorder Society 2004;19(2):217-20.
2004: Kabakci K; Hedrich K; Leung J C; Mitterer M; Vieregge P; Lencer R; Hagenah J; Garrels J; Witt K; Klostermann F; Svetel M; Friedman J; Kostic V; Bressman S B; Breakefield X O; Ozelius L J; Pramstaller P P; Klein C
Mutations in DYT1: extension of the phenotypic and mutational spectrum.
Neurology 2004;62(3):395-400.
2004: Hedrich K; Djarmati A; Schäfer N; Hering R; Wellenbrock C; Weiss P H; Hilker R; Vieregge P; Ozelius L J; Heutink P; Bonifati V; Schwinger E; Lang A E; Noth J; Bressman S B; Pramstaller P P; Riess O; Klein C
DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease.
Neurology 2004;62(3):389-94.
2004: Hedrich Katja; Schäfer Nora; Hering Robert; Hagenah Johann; Lanthaler Andrea J; Schwinger Eberhard; Kramer Patricia L; Ozelius Laurie J; Bressman Susan B; Abbruzzese Giovanni; Martinelli Paolo; Kostic Vladimir; Pramstaller Peter P; Vieregge Peter; Riess Olaf; Klein Christine
The R98Q variation in DJ-1 represents a rare polymorphism.
Annals of neurology 2004;55(1):145; author reply 145-6.
2003: Karamohamed S; DeStefano A L; Wilk J B; Shoemaker C M; Golbe L I; Mark M H; Lazzarini A M; Suchowersky O; Labelle N; Guttman M; Currie L J; Wooten G F; Stacy M; Saint-Hilaire M; Feldman R G; Sullivan K M; Xu G; Watts R; Growdon J; Lew M; Waters C; Vieregge P; Pramstaller P P; Klein C; Racette B A; Perlmutter J S; Parsian A; Singer C; Montgomery E; Baker K; Gusella J F; Fink S J; Myers R H; Herbert A;
A haplotype at the PARK3 locus influences onset age for Parkinson's disease: the GenePD study.
Neurology 2003;61(11):1557-61.
2003: Denison Stacy R; Wang Fang; Becker Nicole A; Schüle Birgitt; Kock Norman; Phillips Leslie A; Klein Christine; Smith David I
Alterations in the common fragile site gene Parkin in ovarian and other cancers.
Oncogene 2003;22(51):8370-8.
2003: Wellenbrock Claudia; Hedrich Katja; Schäfer Nora; Kasten Meike; Jacobs Helfried; Schwinger Eberhard; Hagenah Johann; Pramstaller Peter P; Vieregge Peter; Klein Christine
NR4A2 mutations are rare among European patients with familial Parkinson's disease.
Annals of neurology 2003;54(3):415.
2003: Klein Christine; Hedrich Katja; Wellenbrock Claudia; Kann Martin; Harris Juliette; Marder Karen; Lang Anthony E; Schwinger Eberhard; Ozelius Laurie J; Vieregge Peter; Pramstaller Peter P; Kramer Patricia L
Frequency of parkin mutations in late-onset Parkinson's disease.
Annals of neurology 2003;54(3):415-6; author reply 416-7.
2003: Foncke E M J; Klein C; Koelman J H T M; Kramer P L; Schilling K; Müller B; Garrels J; de Carvalho Aguiar P; Liu L; de Froe A; Speelman J D; Ozelius L J; Tijssen M A J
Hereditary myoclonus-dystonia associated with epilepsy.
Neurology 2003;60(12):1988-90.
2003: Lincoln S; Wiley J; Lynch T; Langston J W; Chen R; Lang A; Rogaeva E; Sa D S; Munhoz R P; Harris J; Marder K; Klein C; Bisceglio G; Hussey J; West A; Hulihan M; Hardy J; Farrer M
Parkin-proven disease: common founders but divergent phenotypes.
Neurology 2003;60(10):1605-10.
2003: Maniak S; Sieberer M; Hagenah J; Klein C; Vieregge P
Focal and segmental primary dystonia in north-western Germany--a clinico-genetic study.
Acta neurologica Scandinavica 2003;107(3):228-32.
2002: Klein C; Hedrich K; Kabakçi K; Mohrmann K; Wiegers K; Landt O; Hagenah J; Schwinger E; Pramstaller P P; Ozelius L J; Gucuyener K; Aysun S; Demir E
Exon deletions in the GCHI gene in two of four Turkish families with dopa-responsive dystonia.
Neurology 2002;59(11):1783-6.
2002: Müller Birgitt; Hedrich Katja; Kock Norman; Dragasevic Natasa; Svetel Marina; Garrels Jennifer; Landt Olfert; Nitschke Matthias; Pramstaller Peter P; Reik Wolf; Schwinger Eberhard; Sperner Jürgen; Ozelius Laurie; Kostic Vladimir; Klein Christine
Evidence that paternal expression of the epsilon-sarcoglycan gene accounts for reduced penetrance in myoclonus-dystonia.
American journal of human genetics 2002;71(6):1303-11.
2002: Klein Christine; Liu Liu; Doheny Dana; Kock Norman; Müller Birgitt; de Carvalho Aguiar Patricia; Leung Joanne; de Leon Deborah; Bressman Susan B; Silverman Jeremy; Smith Christopher; Danisi Fabio; Morrison Chris; Walker Ruth H; Velickovic Miodrag; Schwinger Eberhard; Kramer Patricia L; Breakefield Xandra O; Brin Mitchell F; Ozelius Laurie J
Epsilon-sarcoglycan mutations found in combination with other dystonia gene mutations.
Annals of neurology 2002;52(5):675-9.
2002: Doheny D; Danisi F; Smith C; Morrison C; Velickovic M; De Leon D; Bressman S B; Leung J; Ozelius L; Klein C; Breakefield X O; Brin M F; Silverman J M
Clinical findings of a myoclonus-dystonia family with two distinct mutations.
Neurology 2002;59(8):1244-6.
2002: Doheny D O; Brin M F; Morrison C E; Smith C J; Walker R H; Abbasi S; Müller B; Garrels J; Liu L; De Carvalho Aguiar P; Schilling K; Kramer P; De Leon D; Raymond D; Saunders-Pullman R; Klein C; Bressman S B; Schmand B; Tijssen M A J; Ozelius L J; Silverman J M
Phenotypic features of myoclonus-dystonia in three kindreds.
Neurology 2002;59(8):1187-96.
2002: Bubel S; Peters V; Klein C; Hackler R; Schaefer J R; Hagenah J; Hoffmann G F; Vieregge P
[CDG (congenital disorders of glycosylation). Differential hereditary ataxia in adulthood diagnosis]
Der Nervenarzt 2002;73(8):754-60.
2002: Kock Norman; Müller Birgitt; Vieregge Peter; Pramstaller Peter P; Marder Karen; Abbruzzese Giovanni; Martinelli Paolo; Lang Anthony E; Jacobs Helfried; Hagenah Johann; Harris Juliette; Meija-Santana Helen; Fahn Stanley; Hedrich Katja; Kann Martin; Gehlken Ulrike; Culjkovic Biljana; Schwinger Eberhard; Wszolek Zbigniew K; Zühlke Christine; Klein Christine
Role of SCA2 mutations in early- and late-onset dopa-responsive parkinsonism.
Annals of neurology 2002;52(2):257-8; author reply 258.
2002: Augood Sarah J; Hollingsworth Z; Albers D S; Yang L; Leung J-C; Muller B; Klein C; Breakefield X O; Standaert D G
Dopamine transmission in DYT1 dystonia: a biochemical and autoradiographical study.
Neurology 2002;59(3):445-8.
2002: Klein Christine; Ozelius Laurie J
Dystonia: clinical features, genetics, and treatment.
Current opinion in neurology 2002;15(4):491-7.
2002: Pal Pramod K; Leung Joanne; Hedrich Katya; Samii Ali; Lieberman Abraham; Nausieda Paul A; Calne Donald B; Breakefield Xandra O; Klein Christine; Stoessl A Jon
[18F]-Dopa positron emission tomography imaging in early-stage, non-parkin juvenile parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2002;17(4):789-94.
2002: Kock Norman; Culjkovic Biljana; Maniak Susanna; Schilling Karla; Müller Birgitt; Zühlke Christine; Ozelius Laurie; Klein Christine; Pramstaller Peter P; Kramer Patricia L
Mode of inheritance and susceptibility locus for restless legs syndrome, on chromosome 12q.
American journal of human genetics 2002;71(1):205-8; author reply 208.
2002: Kis B; Schrag A; Ben-Shlomo Y; Klein C; Gasperi A; Spoegler F; Schoenhuber R; Pramstaller P P
Novel three-stage ascertainment method: prevalence of PD and parkinsonism in South Tyrol, Italy.
Neurology 2002;58(12):1820-5.
2002: Kann Martin; Jacobs Helfried; Mohrmann Kathrin; Schumacher Kirsten; Hedrich Katja; Garrels Jennifer; Wiegers Karin; Schwinger Eberhard; Pramstaller Peter P; Breakefield Xandra O; Ozelius Laurie J; Vieregge Peter; Klein Christine
Role of parkin mutations in 111 community-based patients with early-onset parkinsonism.
Annals of neurology 2002;51(5):621-5.
2002: DeStefano Anita L; Lew Mark F; Golbe Lawrence I; Mark Margery H; Lazzarini Alice M; Guttman Mark; Montgomery Erwin; Waters Cheryl H; Singer Carlos; Watts Ray L; Currie Lillian J; Wooten G Frederick; Maher Nancy E; Wilk Jemma B; Sullivan Kristin M; Slater Karen M; Saint-Hilaire Marie H; Feldman Robert G; Suchowersky Oksana; Lafontaine Anne-Louise; Labelle Nancy; Growdon John H; Vieregge Peter; Pramstaller Peter P; Klein Christine; Hubble Jean P; Reider Carson R; Stacy Mark; MacDonald Marcy E; Gusella James F; Myers Richard H
PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study.
American journal of human genetics 2002;70(5):1089-95.
2002: Hedrich K; Marder K; Harris J; Kann M; Lynch T; Meija-Santana H; Pramstaller P P; Schwinger E; Bressman S B; Fahn S; Klein C
Evaluation of 50 probands with early-onset Parkinson's disease for Parkin mutations.
Neurology 2002;58(8):1239-46.
2002: Hilker Rüdiger; Klein Christine; Hedrich Katja; Ozelius Laurie J; Vieregge Peter; Herholz Karl; Pramstaller Peter P; Heiss Wolf Dieter
The striatal dopaminergic deficit is dependent on the number of mutant alleles in a family with mutations in the parkin gene: evidence for enzymatic parkin function in humans.
Neuroscience letters 2002;323(1):50-4.
2002: Pramstaller Peter P; Kis Bernhard; Eskelson Cordula; Hedrich Katja; Scherer Monika; Schwinger Eberhard; Breakefield Xandra O; Kramer Patricia L; Ozelius Laurie J; Klein Christine
Phenotypic variability in a large kindred (Family LA) with deletions in the parkin gene.
Movement disorders : official journal of the Movement Disorder Society 2002;17(2):424-6.
2002: Vitaliani Roberta; Scaravilli Tomaso; Egarter-Vigl Eduard; Giometto Bruno; Klein Christine; Scaravilli Francesco; An Shu F; Pramstaller Peter P
The pathology of the spinal cord in progressive supranuclear palsy.
Journal of neuropathology and experimental neurology 2002;61(3):268-74.
2002: Kann M; Hedrich K; Vieregge P; Jacobs H; Müller B; Kock N; Schwinger E; Klein C; Marder K; Harris J; Meija-Santana H; Bressman S; Ozelius L J; Lang A E; Pramstaller P P
The parkin gene is not involved in late-onset Parkinson's disease.
Neurology 2002;58(5):835; author reply 835.
2002: Pramstaller P P; Künig G; Leenders K; Kann M; Hedrich K; Vieregge P; Goetz C G; Klein C
Parkin mutations in a patient with hemiparkinsonism-hemiatrophy: a clinical-genetic and PET study.
Neurology 2002;58(5):808-10.
2002: Saunders-Pullman R; Shriberg J; Heiman G; Raymond D; Wendt K; Kramer P; Schilling K; Kurlan R; Klein C; Ozelius L J; Risch N J; Bressman S B
Myoclonus dystonia: possible association with obsessive-compulsive disorder and alcohol dependence.
Neurology 2002;58(2):242-5.
2002: Maher N E; Golbe L I; Lazzarini A M; Mark M H; Currie L J; Wooten G F; Saint-Hilaire M; Wilk J B; Volcjak J; Maher J E; Feldman R G; Guttman M; Lew M; Waters C H; Schuman S; Suchowersky O; Lafontaine A L; Labelle N; Vieregge P; Pramstaller P P; Klein C; Hubble J; Reider C; Growdon J; Watts R; Montgomery E; Baker K; Singer C; Stacy M; Myers R H
Epidemiologic study of 203 sibling pairs with Parkinson's disease: the GenePD study.
Neurology 2002;58(1):79-84.
2001: Nitschke M F; Krüger G; Bruhn H; Klein C; Gehrking E; Wessel K; Frahm J; Vieregge P
Voluntary palatal tremor is associated with hyperactivation of the inferior olive: a functional magnetic resonance imaging study.
Movement disorders : official journal of the Movement Disorder Society 2001;16(6):1193-5.
2001: DeStefano A L; Golbe L I; Mark M H; Lazzarini A M; Maher N E; Saint-Hilaire M; Feldman R G; Guttman M; Watts R L; Suchowersky O; Lafontaine A L; Labelle N; Lew M F; Waters C H; Growdon J H; Singer C; Currie L J; Wooten G F; Vieregge P; Pramstaller P P; Klein C; Hubble J P; Stacy M; Montgomery E; MacDonald M E; Gusella J F; Myers R H
Genome-wide scan for Parkinson's disease: the GenePD Study.
Neurology 2001;57(6):1124-6.
2001: Hedrich K; Kann M; Lanthaler A J; Dalski A; Eskelson C; Landt O; Schwinger E; Vieregge P; Lang A E; Breakefield X O; Ozelius L J; Pramstaller P P; Klein C
The importance of gene dosage studies: mutational analysis of the parkin gene in early-onset parkinsonism.
Human molecular genetics 2001;10(16):1649-56.
2001: Leung J C; Klein C; Friedman J; Vieregge P; Jacobs H; Doheny D; Kamm C; DeLeon D; Pramstaller P P; Penney J B; Eisengart M; Jankovic J; Gasser T; Bressman S B; Corey D P; Kramer P; Brin M F; Ozelius L J; Breakefield X O
Novel mutation in the TOR1A (DYT1) gene in atypical early onset dystonia and polymorphisms in dystonia and early onset parkinsonism.
Neurogenetics 2001;3(3):133-43.
2001: Klein C
[The genetics of Parkinson syndrome]
Praxis 2001;90(23):1015-23.
2001: Zühlke C; Hellenbroich Y; Dalski A; Kononowa N; Hagenah J; Vieregge P; Riess O; Klein C; Schwinger E
Different types of repeat expansion in the TATA-binding protein gene are associated with a new form of inherited ataxia.
European journal of human genetics : EJHG 2001;9(3):160-4.
2001: Hilker R; Klein C; Ghaemi M; Kis B; Strotmann T; Ozelius L J; Lenz O; Vieregge P; Herholz K; Heiss W D; Pramstaller P P
Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene.
Annals of neurology 2001;49(3):367-76.
2000: Kis B; Heberlein I; Hagenah J; Jacobs H; Klein C; Vieregge P
Neuropsychological abnormalities in first degree relatives of patients with familial Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 2000;69(6):838.
2000: Friedman J R; Klein C; Leung J; Woodward H; Ozelius L J; Breakefield X O; Charness M E
The GAG deletion of the DYT1 gene is infrequent in musicians with focal dystonia.
Neurology 2000;55(9):1417-8.
2000: Klein C; Schilling K; Saunders-Pullman R J; Garrels J; Breakefield X O; Brin M F; deLeon D; Doheny D; Fahn S; Fink J S; Forsgren L; Friedman J; Frucht S; Harris J; Holmgren G; Kis B; Kurlan R; Kyllerman M; Lang A E; Leung J; Raymond D; Robishaw J D; Sanner G; Schwinger E; Tabamo R E; Tagliati M
A major locus for myoclonus-dystonia maps to chromosome 7q in eight families.
American journal of human genetics 2000;67(5):1314-9.
2000: Klein C; Schumacher K; Jacobs H; Hagenah J; Kis B; Garrels J; Schwinger E; Ozelius L; Pramstaller P; Vieregge P; Kramer P L
Association studies of Parkinson's disease and parkin polymorphisms.
Annals of neurology 2000;48(1):126-7.
2000: Klein C; Pramstaller P P; Kis B; Page C C; Kann M; Leung J; Woodward H; Castellan C C; Scherer M; Vieregge P; Breakefield X O; Kramer P L; Ozelius L J
Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: expanding the phenotype.
Annals of neurology 2000;48(1):65-71.
2000: Klein C; Kann M; Kis B; Pramstaller P P; Breakefield X O; Ozelius L J; Vieregge P
[Genetics of dystonia]
Der Nervenarzt 2000;71(6):431-41.
2000: Bressman S B; Sabatti C; Raymond D; de Leon D; Klein C; Kramer P L; Brin M F; Fahn S; Breakefield X; Ozelius L J; Risch N J
The DYT1 phenotype and guidelines for diagnostic testing.
Neurology 2000;54(9):1746-52.
2000: Klein C; Gurvich N; Sena-Esteves M; Bressman S; Brin M F; Ebersole B J; Fink S; Forsgren L; Friedman J; Grimes D; Holmgren G; Kyllerman M; Lang A E; de Leon D; Leung J; Prioleau C; Raymond D; Sanner G; Saunders-Pullman R; Vieregge P; Wahlström J; Breakefield X O; Kramer P L; Ozelius L J; Sealfon S C
Evaluation of the role of the D2 dopamine receptor in myoclonus dystonia.
Annals of neurology 2000;47(3):369-73.
1999: Ozelius L J; Page C E; Klein C; Hewett J W; Mineta M; Leung J; Shalish C; Bressman S B; de Leon D; Brin M F; Fahn S; Corey D P; Breakefield X O
The TOR1A (DYT1) gene family and its role in early onset torsion dystonia.
Genomics 1999;62(3):377-84.
1999: Sieberer M G; Vieregge P; Klein C; Ozelius L J; Wandinger K P
Concordant late onset of craniocervical dystonia in a pair of monozygotic twins.
Movement disorders : official journal of the Movement Disorder Society 1999;14(6):1040-3.
1999: Nygaard T G; Raymond D; Chen C; Nishino I; Greene P E; Jennings D; Heiman G A; Klein C; Saunders-Pullman R J; Kramer P; Ozelius L J; Bressman S B
Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31.
Annals of neurology 1999;46(5):794-8.
1999: Vieregge P; Hagenah J; Heberlein I; Klein C; Ludin H P
Parkinson's disease in twins: a follow-up study.
Neurology 1999;53(3):566-72.
1999: Kramer P L; Mineta M; Klein C; Schilling K; de Leon D; Farlow M R; Breakefield X O; Bressman S B; Dobyns W B; Ozelius L J; Brashear A
Rapid-onset dystonia-parkinsonism: linkage to chromosome 19q13.
Annals of neurology 1999;46(2):176-82.
1999: Klein C; Vieregge P; Hagenah J; Sieberer M; Doyle E; Jacobs H; Gasser T; Breakefield X O; Risch N J; Ozelius L J
Search for the PARK3 founder haplotype in a large cohort of patients with Parkinson's disease from northern Germany.
Annals of human genetics 1999;63(Pt 4):285-91.
1999: Klein C; Brin M F; Kramer P; Sena-Esteves M; de Leon D; Doheny D; Bressman S; Fahn S; Breakefield X O; Ozelius L J
Association of a missense change in the D2 dopamine receptor with myoclonus dystonia.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5173-6.
1999: Klein C; Page C E; LeWitt P; Gordon M F; de Leon D; Awaad Y; Breakefield X O; Brin M F; Ozelius L J
Genetic analysis of three patients with an 18p- syndrome and dystonia.
Neurology 1999;52(3):649-51.
1999: Klein C; Breakefield X O; Ozelius L J
Genetics of primary dystonia.
Seminars in neurology 1999;19(3):271-80.
1999: Klein C; Friedman J; Bressman S; Vieregge P; Brin M F; Pramstaller P P; De Leon D; Hagenah J; Sieberer M; Fleet C; Kiely R; Xin W; Breakefield X O; Ozelius L J; Sims K B
Genetic testing for early-onset torsion dystonia (DYT1): introduction of a simple screening method, experiences from testing of a large patient cohort, and ethical aspects.
Genetic testing 1999;3(4):323-8.
1999: Hagenah J; Klein C; Sieberer M; Vieregge P
Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: further clinical evidence.
Journal of neural transmission (Vienna, Austria : 1996) 1999;106(3-4):301-7.
1998: Klein C; Ozelius L J; Hagenah J; Breakefield X O; Risch N J; Vieregge P
Search for a founder mutation in idiopathic focal dystonia from Northern Germany.
American journal of human genetics 1998;63(6):1777-82.
1998: Klein C; Vieregge P; Heide W; Kemper B; Hagedorn-Greiwe M; Hagenah J; Vollmer C; Breakefield X O; Kömpf D; Ozelius L
Exclusion of chromosome regions 6p12 and 15q11, but not chromosome region 7p11, in a German family with autosomal dominant congenital nystagmus.
Genomics 1998;54(1):176-7.
1998: Klein C; Pramstaller P P; Castellan C C; Breakefield X O; Kramer P L; Ozelius L J
Clinical and genetic evaluation of a family with a mixed dystonia phenotype from South Tyrol.
Annals of neurology 1998;44(3):394-8.
1998: Klein C; Vieregge P
[Non-epileptic paroxysmal movement disorders]
Der Nervenarzt 1998;69(8):647-59.
1998: Klein C; Brin M F; de Leon D; Limborska S A; Ivanova-Smolenskaya I A; Bressman S B; Friedman A; Markova E D; Risch N J; Breakefield X O; Ozelius L J
De novo mutations (GAG deletion) in the DYT1 gene in two non-Jewish patients with early-onset dystonia.
Human molecular genetics 1998;7(7):1133-6.
1998: Klein C; Vieregge P
Fahr's disease--far from a disease.
Movement disorders : official journal of the Movement Disorder Society 1998;13(3):620-1.
1998: Klein C; Gehrking E; Vieregge P
Voluntary palatal tremor in two siblings.
Movement disorders : official journal of the Movement Disorder Society 1998;13(3):545-8.
1997: Wszolek Z K; Vieregge P; Uitti R J; Gasser T; Yasuhara O; McGeer P; Berry K; Calne D B; Vingerhoets F J; Klein C; Pfeiffer R F
German-Canadian family (family A) with parkinsonism, amyotrophy, and dementia - Longitudinal observations.
Parkinsonism & related disorders 1997;3(3):125-39.
1997: Klein C; Brown R; Wenning G; Quinn N
The "cold hands sign" in multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society 1997;12(4):514-8.
1997: Vieregge P; Klein C; Gehrking E; Körtke D; Kömpf D
The diagnosis of 'essential palatal tremor'.
Neurology 1997;49(1):248-9.
1997: Klein C; Kömpf D; Pulkowski U; Moser A; Vieregge P
A study of visual hallucinations in patients with Parkinson's disease.
Journal of neurology 1997;244(6):371-7.
1997: Klein C; Vieregge P; Kömpf D
Paroxysmal choreoathetosis in a patient with idiopathic basal ganglia calcification, chorea, and dystonia.
Movement disorders : official journal of the Movement Disorder Society 1997;12(2):254-5.
1997: Vieregge P; Stolze H; Klein C; Heberlein I
Gait quantitation in Parkinson's disease--locomotor disability and correlation to clinical rating scales.
Journal of neural transmission (Vienna, Austria : 1996) 1997;104(2-3):237-48.
1982: Sandyk R; Klein C
Progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome). A case report.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1982;62(18):667-8.

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