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Hynda Kleinman

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Co-Publications
Name
37
Yamada, Yoshihiko
30
Nomizu, Motoyoshi
16
Hoffman, Matthew
13
Grant, Derrick
10
Kuratomi, Y
10
Philp, Deborah
9
Malinda, KM
9
Engbring, Jean
8
Song, SY
7
Goldstein, Allan
7
Elkin, Michael
7
Ponce, Lourdes
6
Lugassy, Claire
6
Gho, Yong Song
6
Barnhill, Raymond

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Publications

TOP 3
Lugassy Claire; Torres-Muñoz Jorge E; Kleinman Hynda K; Ghanem Ghanem; Vernon Stephen; Barnhill Raymond L
Overexpression of malignancy-associated laminins and laminin receptors by angiotropic human melanoma cells in a chick chorioallantoic membrane model.
Arnaoutova Irina; George Jay; Kleinman Hynda K; Benton Gabriel
The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art.
Yoshida Yoshio; Kurokawa Tetsuji; Nishikawa Yukiko; Orisa Makoto; Kleinman Hynda K; Kotsuji Fumikazu
Laminin-1-derived scrambled peptide AG73T disaggregates laminin-1-induced ovarian cancer cell spheroids and improves the efficacy of cisplatin.

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All Publications

2009: Lugassy Claire; Torres-Muñoz Jorge E; Kleinman Hynda K; Ghanem Ghanem; Vernon Stephen; Barnhill Raymond L
Overexpression of malignancy-associated laminins and laminin receptors by angiotropic human melanoma cells in a chick chorioallantoic membrane model.
Journal of cutaneous pathology 2009;36(12):1237-43.
2009: Arnaoutova Irina; George Jay; Kleinman Hynda K; Benton Gabriel
The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art.
Angiogenesis 2009;12(3):267-74.
2008: Yoshida Yoshio; Kurokawa Tetsuji; Nishikawa Yukiko; Orisa Makoto; Kleinman Hynda K; Kotsuji Fumikazu
Laminin-1-derived scrambled peptide AG73T disaggregates laminin-1-induced ovarian cancer cell spheroids and improves the efficacy of cisplatin.
International journal of oncology 2008;32(3):673-81.
2008: Malinda Katherine M; Wysocki Annette B; Koblinski Jennifer E; Kleinman Hynda K; Ponce M Lourdes
Angiogenic laminin-derived peptides stimulate wound healing.
The international journal of biochemistry & cell biology 2008;40(12):2771-80.
2007: Lugassy C; Kleinman H K; Vernon S E; Welch D R; Barnhill R L
C16 laminin peptide increases angiotropic extravascular migration of human melanoma cells in a shell-less chick chorioallantoic membrane assay.
The British journal of dermatology 2007;157(4):780-2.
2007: Philp Deborah; St-Surin Sharleen; Cha Hee-Jae; Moon Hye-Sung; Kleinman Hynda K; Elkin Michael
Thymosin beta 4 induces hair growth via stem cell migration and differentiation.
Annals of the New York Academy of Sciences 2007;1112():95-103.
2007: Kipper Matt J; Kleinman Hynda K; Wang Francis W
New method for modeling connective-tissue cell migration: improved accuracy on motility parameters.
Biophysical journal 2007;93(5):1797-808.
2007: Kipper Matt J; Kleinman Hynda K; Wang Francis W
Covalent surface chemistry gradients for presenting bioactive peptides.
Analytical biochemistry 2007;363(2):175-84.
2007: Chen Silvia S; Fitzgerald Wendy; Zimmerberg Joshua; Kleinman Hynda K; Margolis Leonid
Cell-cell and cell-extracellular matrix interactions regulate embryonic stem cell differentiation.
Stem cells (Dayton, Ohio) 2007;25(3):553-61.
2007: Mochizuki Mayumi; Philp Deborah; Hozumi Kentaro; Suzuki Nobuharu; Yamada Yoshihiko; Kleinman Hynda K; Nomizu Motoyoshi
Angiogenic activity of syndecan-binding laminin peptide AG73 (RKRLQVQLSIRT).
Archives of biochemistry and biophysics 2007;459(2):249-55.
2007: Mochizuki Mayumi; Yamagata Natsumi; Philp Deborah; Hozumi Kentaro; Watanabe Tadashi; Kikkawa Yamato; Kadoya Yuichi; Kleinman Hynda K; Nomizu Motoyoshi
Integrin-dependent cell behavior on ECM peptide-conjugated chitosan membranes.
Biopolymers 2007;88(2):122-30.
2006: Cid M C; Hoffman M P; Hernández-Rodríguez J; Segarra M; Elkin M; Sánchez M; Vilardell C; García-Martínez A; Pla-Campo M; Grau J M; Kleinman H K
Association between increased CCL2 (MCP-1) expression in lesions and persistence of disease activity in giant-cell arteritis.
Rheumatology (Oxford, England) 2006;45(11):1356-63.
2006: Moon Hye-Sung; Even-Ram Sharona; Kleinman Hynda K; Cha Hee-Jae
Zyxin is upregulated in the nucleus by thymosin beta4 in SiHa cells.
Experimental cell research 2006;312(17):3425-31.
2006: Movafagh Sharareh; Hobson John P; Spiegel Sarah; Kleinman Hynda K; Zukowska Zofia
Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(11):1924-6.
2006: Philp Deborah; Scheremeta Brooke; Sibliss Kedesha; Zhou Min; Fine Esther L; Nguyen Mychi; Wahl Larry; Hoffman Matthew P; Kleinman Hynda K
Thymosin beta4 promotes matrix metalloproteinase expression during wound repair.
Journal of cellular physiology 2006;208(1):195-200.
2006: Lugassy Claire; Vernon Stephen E; Busam Klaus; Engbring Jean A; Welch Danny R; Poulos Evangelos G; Kleinman Hynda K; Barnhill Raymond L
Angiotropism of human melanoma: studies involving in transit and other cutaneous metastases and the chicken chorioallantoic membrane: implications for extravascular melanoma invasion and metastasis.
The American Journal of dermatopathology 2006;28(3):187-93.
2006: Devadas Krishnakumar; Boykins Robert A; Hardegen Neil J; Philp Deborah; Kleinman Hynda K; Osa Etin-Osa; Wang Jiun; Clouse Kathleen A; Wahl Larry M; Hewlett Indira K; Rappaport Jay; Yamada Kenneth M; Dhawan Subhash
Selective side-chain modification of cysteine and arginine residues blocks pathogenic activity of HIV-1-Tat functional peptides.
Peptides 2006;27(4):611-21.
2006: Hatakeyama J; Philp D; Hatakeyama Y; Haruyama N; Shum L; Aragon M A; Yuan Z; Gibson C W; Sreenath T; Kleinman H K; Kulkarni A B
Amelogenin-mediated regulation of osteoclastogenesis, and periodontal cell proliferation and migration.
Journal of dental research 2006;85(2):144-9.
2005: Hibino Suguru; Shibuya Masahiko; Hoffman Matthew P; Engbring Jean A; Hossain Rydhwana; Mochizuki Mayumi; Kudoh Shoji; Nomizu Motoyoshi; Kleinman Hynda K
Laminin alpha5 chain metastasis- and angiogenesis-inhibiting peptide blocks fibroblast growth factor 2 activity by binding to the heparan sulfate chains of CD44.
Cancer research 2005;65(22):10494-501.
2005: Kleinman Hynda K; Martin George R
Matrigel: basement membrane matrix with biological activity.
Seminars in cancer biology 2005;15(5):378-86.
2005: Goldstein Allan L; Hannappel Ewald; Kleinman Hynda K
Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues.
Trends in molecular medicine 2005;11(9):421-9.
2005: Koblinski Jennifer E; Kaplan-Singer Benjamin R; VanOsdol Sherilyn J; Wu Michael; Engbring Jean A; Wang Songlin; Goldsmith Corinne M; Piper John T; Vostal Jaroslav G; Harms John F; Welch Danny R; Kleinman Hynda K
Endogenous osteonectin/SPARC/BM-40 expression inhibits MDA-MB-231 breast cancer cell metastasis.
Cancer research 2005;65(16):7370-7.
2005: Yokoyama Fumiharu; Suzuki Nobuharu; Kadoya Yuichi; Utani Atsushi; Nakatsuka Hiroko; Nishi Norio; Haruki Masahiro; Kleinman Hynda K; Nomizu Motoyoshi
Bifunctional peptides derived from homologous loop regions in the laminin alpha chain LG4 modules interact with both alpha 2 beta 1 integrin and syndecan-2.
Biochemistry 2005;44(28):9581-9.
2005: Koblinski Jennifer E; Wu Michael; Demeler Borries; Jacob Karin; Kleinman Hynda K
Matrix cell adhesion activation by non-adhesion proteins.
Journal of cell science 2005;118(Pt 13):2965-74.
2005: Zcharia Eyal; Philp Deborah; Edovitsky Evgeny; Aingorn Helena; Metzger Shula; Kleinman Hynda K; Vlodavsky Israel; Elkin Michael
Heparanase regulates murine hair growth.
The American journal of pathology 2005;166(4):999-1008.
2005: Philp Deborah; Chen Silvia S; Fitzgerald Wendy; Orenstein Jan; Margolis Leonid; Kleinman Hynda K
Complex extracellular matrices promote tissue-specific stem cell differentiation.
Stem cells (Dayton, Ohio) 2005;23(2):288-96.
2005: Huh Jung-Im; Calvo Alfonso; Stafford Jeffrey; Cheung Mui; Kumar Rakesh; Philp Deborah; Kleinman Hynda K; Green Jeffrey E
Inhibition of VEGF receptors significantly impairs mammary cancer growth in C3(1)/Tag transgenic mice through antiangiogenic and non-antiangiogenic mechanisms.
Oncogene 2005;24(5):790-800.
2004: Yokoyama Fumiharu; Suzuki Nobuharu; Haruki Masahiro; Nishi Norio; Oishi Shinya; Fujii Nobutaka; Utani Atsushi; Kleinman Hynda K; Nomizu Motoyoshi
Cyclic peptides from the loop region of the laminin alpha 4 chain LG4 module show enhanced biological activity over linear peptides.
Biochemistry 2004;43(42):13590-7.
2004: Hibino Suguru; Shibuya Masahiko; Engbring Jean A; Mochizuki Mayumi; Nomizu Motoyoshi; Kleinman Hynda K
Identification of an active site on the laminin alpha5 chain globular domain that binds to CD44 and inhibits malignancy.
Cancer research 2004;64(14):4810-6.
2004: Hwang Jungsu; Kim Chan Woo; Son Kyung-No; Han Kyu Yeon; Lee Kyung Hee; Kleinman Hynda K; Ko Jesang; Na Doe Sun; Kwon Byoung S; Gho Yong Song; Kim Jiyoung
Angiogenic activity of human CC chemokine CCL15 in vitro and in vivo.
FEBS letters 2004;570(1-3):47-51.
2004: Elkin Michael; Orgel Adam; Kleinman Hynda K
An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1.
Journal of the National Cancer Institute 2004;96(11):875-8.
2004: Lugassy Claire; Kleinman Hynda K; Engbring Jean A; Welch Danny R; Harms John F; Rufner Robyn; Ghanem Ghanem; Patierno Steven R; Barnhill Raymond L
Pericyte-like location of GFP-tagged melanoma cells: ex vivo and in vivo studies of extravascular migratory metastasis.
The American journal of pathology 2004;164(4):1191-8.
2004: Philp D; Goldstein A L; Kleinman H K
Thymosin beta4 promotes angiogenesis, wound healing, and hair follicle development.
Mechanisms of ageing and development 2004;125(2):113-5.
2004: Sosne Gabriel; Xu Lihua; Prach Lisa; Mrock Linda K; Kleinman Hynda K; Letterio John J; Hazlett Linda D; Kurpakus-Wheater Michelle
Thymosin beta 4 stimulates laminin-5 production independent of TGF-beta.
Experimental cell research 2004;293(1):175-83.
2004: Philp Deborah; Nguyen Mychi; Scheremeta Brooke; St-Surin Sharleen; Villa Ana M; Orgel Adam; Kleinman Hynda K; Elkin Michael
Thymosin beta4 increases hair growth by activation of hair follicle stem cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(2):385-7.
2003: Elkin Michael; Cohen Irit; Zcharia Eyal; Orgel Adam; Guatta-Rangini Zehava; Peretz Tamar; Vlodavsky Israel; Kleinman Hynda K
Regulation of heparanase gene expression by estrogen in breast cancer.
Cancer research 2003;63(24):8821-6.
2003: Cha Hee-Jae; Jeong Moon-Jin; Kleinman Hynda K
Role of thymosin beta4 in tumor metastasis and angiogenesis.
Journal of the National Cancer Institute 2003;95(22):1674-80.
2003: Philp Deborah; Huff Thomas; Gho Yong Song; Hannappel Ewald; Kleinman Hynda K
The actin binding site on thymosin beta4 promotes angiogenesis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(14):2103-5.
2003: Suzuki Nobuharu; Nakatsuka Hiroko; Mochizuki Mayumi; Nishi Norio; Kadoya Yuichi; Utani Atsushi; Oishi Shinya; Fujii Nobutaka; Kleinman Hynda K; Nomizu Motoyoshi
Biological activities of homologous loop regions in the laminin alpha chain G domains.
The Journal of biological chemistry 2003;278(46):45697-705.
2003: Kleinman Hynda K; Philp Deborah; Hoffman Matthew P
Role of the extracellular matrix in morphogenesis.
Current opinion in biotechnology 2003;14(5):526-32.
2003: Ponce M Lourdes; Hibino Suguru; Lebioda Agata M; Mochizuki Mayumi; Nomizu Motoyoshi; Kleinman Hynda K
Identification of a potent peptide antagonist to an active laminin-1 sequence that blocks angiogenesis and tumor growth.
Cancer research 2003;63(16):5060-4.
2003: Engbring Jean A; Kleinman Hynda K
The basement membrane matrix in malignancy.
The Journal of pathology 2003;200(4):465-70.
2003: Hernández-Rodríguez José; Segarra Marta; Vilardell Carme; Sánchez Montse; García-Martínez Ana; Esteban María-José; Grau Josep M; Urbano-Márquez Alvaro; Colomer Dolors; Kleinman Hynda K; Cid Maria C
Elevated production of interleukin-6 is associated with a lower incidence of disease-related ischemic events in patients with giant-cell arteritis: angiogenic activity of interleukin-6 as a potential protective mechanism.
Circulation 2003;107(19):2428-34.
2003: Ponce M Lourdes; Kleinman Hynda K
Identification of redundant angiogenic sites in laminin alpha1 and gamma1 chains.
Experimental cell research 2003;285(2):189-95.
2003: Philp Deborah; Badamchian Mahnaz; Scheremeta Brooke; Nguyen Mychi; Goldstein Allan L; Kleinman Hynda K
Thymosin beta 4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair in db/db diabetic mice and in aged mice.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2003;11(1):19-24.
2002: Schneider Gregory P; Salcedo Rosalba; Dong Hui Fang; Kleinman Hynda K; Oppenheim Joost J; Howard O M Zack
Suradista NSC 651016 inhibits the angiogenic activity of CXCL12-stromal cell-derived factor 1alpha.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3955-60.
2002: Lugassy Claire; Haroun Raymond I; Brem Henry; Tyler Betty M; Jones Robert V; Fernandez Patricia M; Patierno Steven R; Kleinman Hynda K; Barnhill Raymond L
Pericytic-like angiotropism of glioma and melanoma cells.
The American Journal of dermatopathology 2002;24(6):473-8.
2002: Hoffman Matthew P; Kidder Benjamin L; Steinberg Zachary L; Lakhani Saba; Ho Susan; Kleinman Hynda K; Larsen Melinda
Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanisms.
Development (Cambridge, England) 2002;129(24):5767-78.
2002: Mulligan-Kehoe Mary Jo; Kleinman Hynda K; Drinane Mary; Wagner Robert J; Wieland Courtney; Powell Richard J
A truncated plasminogen activator inhibitor-1 protein blocks the availability of heparin-binding vascular endothelial growth factor A isoforms.
The Journal of biological chemistry 2002;277(50):49077-89.
2002: Kim Chan Woo; Lee Hwan Myung; Lee Tae Hoon; Kang Chulhun; Kleinman Hynda K; Gho Yong Song
Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin.
Cancer research 2002;62(21):6312-7.
2002: Yamada Masanori; Kadoya Yuichi; Kasai Shingo; Kato Kozue; Mochizuki Mayumi; Nishi Norio; Watanabe Nobuhisa; Kleinman Hynda K; Yamada Yoshihiko; Nomizu Motoyoshi
Ile-Lys-Val-Ala-Val (IKVAV)-containing laminin alpha1 chain peptides form amyloid-like fibrils.
FEBS letters 2002;530(1-3):48-52.
2002: Cid Maria C; Hernández-Rodríguez José; Esteban María-José; Cebrián Mireia; Gho Yong Song; Font Carme; Urbano-Márquez Alvaro; Grau Josep M; Kleinman Hynda K
Tissue and serum angiogenic activity is associated with low prevalence of ischemic complications in patients with giant-cell arteritis.
Circulation 2002;106(13):1664-71.
2002: Hecht Dalit; Jung Dale; Prabhu Vinay V; Munson Peter J; Hoffman Matthew P; Kleinman Hynda K
Metallothionein promotes laminin-1-induced acinar differentiation in vitro and reduces tumor growth in vivo.
Cancer research 2002;62(18):5370-4.
2002: Lugassy Claire; Kleinman Hynda K; Fernandez Patricia M; Patierno Steven R; Webber Mukta M; Ghanem Ghanem; Spatz Alain; Barnhill Raymond L
Human melanoma cell migration along capillary-like structures in vitro: a new dynamic model for studying extravascular migratory metastasis.
The Journal of investigative dermatology 2002;119(3):703-4.
2002: Martínez Alfredo; Vos Michele; Guédez Liliana; Kaur Gurmeet; Chen Zhong; Garayoa Mercedes; Pío Rubén; Moody Terry; Stetler-Stevenson William G; Kleinman Hynda K; Cuttitta Frank
The effects of adrenomedullin overexpression in breast tumor cells.
Journal of the National Cancer Institute 2002;94(16):1226-37.
2002: Clement Paul M J; Hanauske-Abel Hartmut M; Wolff Edith C; Kleinman Hynda K; Park Myung Hee
The antifungal drug ciclopirox inhibits deoxyhypusine and proline hydroxylation, endothelial cell growth and angiogenesis in vitro.
International journal of cancer. Journal international du cancer 2002;100(4):491-8.
2002: Cid Maria C; Schnaper H William; Kleinman Hynda K
Estrogens and the vascular endothelium.
Annals of the New York Academy of Sciences 2002;966():143-57.
2002: Engbring Jean A; Hoffman Matthew P; Karmand Arezo J; Kleinman Hynda K
The B16F10 cell receptor for a metastasis-promoting site on laminin-1 is a heparan sulfate/chondroitin sulfate-containing proteoglycan.
Cancer research 2002;62(12):3549-54.
2002: Kuratomi Y; Nomizu M; Tanaka K; Ponce M L; Komiyama S; Kleinman H K; Yamada Y
Laminin gamma 1 chain peptide, C-16 (KAFDITYVRLKF), promotes migration, MMP-9 secretion, and pulmonary metastasis of B16-F10 mouse melanoma cells.
British journal of cancer 2002;86(7):1169-73.
2002: Sosne Gabriel; Szliter Elizabeth A; Barrett Ronald; Kernacki Karen A; Kleinman Hynda; Hazlett Linda D
Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury.
Experimental eye research 2002;74(2):293-9.
2001: Nomizu M; Yokoyama F; Suzuki N; Okazaki I; Nishi N; Ponce M L; Kleinman H K; Yamamoto Y; Nakagawa S; Mayumi T
Identification of homologous biologically active sites on the N-terminal domain of laminin alpha chains.
Biochemistry 2001;40(50):15310-7.
2001: Salcedo R; Young H A; Ponce M L; Ward J M; Kleinman H K; Murphy W J; Oppenheim J J
Eotaxin (CCL11) induces in vivo angiogenic responses by human CCR3+ endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7571-8.
2001: Ponce M L; Nomizu M; Kleinman H K
An angiogenic laminin site and its antagonist bind through the alpha(v)beta3 and alpha5beta1 integrins.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(8):1389-97.
2001: Hoffman M P; Engbring J A; Nielsen P K; Vargas J; Steinberg Z; Karmand A J; Nomizu M; Yamada Y; Kleinman H K
Cell type-specific differences in glycosaminoglycans modulate the biological activity of a heparin-binding peptide (RKRLQVQLSIRT) from the G domain of the laminin alpha1 chain.
The Journal of biological chemistry 2001;276(25):22077-85.
2001: Kleinman H K; Cid M C
Preparation of endothelial cells.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2001;Chapter 2():Unit 2.3.
2001: Kleinman H K; Jacob K
Invasion assays.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2001;Chapter 12():Unit 12.2.
2001: Kleinman H K
Preparation of gelled substrates.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2001;Chapter 10():Unit 10.3.
2001: Kleinman H K
Preparation of basement membrane components from EHS tumors.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2001;Chapter 10():Unit 10.2.
2001: Gho Y S; Kim P N; Li H C; Elkin M; Kleinman H K
Stimulation of tumor growth by human soluble intercellular adhesion molecule-1.
Cancer research 2001;61(10):4253-7.
2001: Sosne G; Chan C C; Thai K; Kennedy M; Szliter E A; Hazlett L D; Kleinman H K
Thymosin beta 4 promotes corneal wound healing and modulates inflammatory mediators in vivo.
Experimental eye research 2001;72(5):605-8.
2001: Kleinman H K; Koblinski J; Lee S; Engbring J
Role of basement membrane in tumor growth and metastasis.
Surgical oncology clinics of North America 2001;10(2):329-38, ix.
2000: Jung D W; Hecht D; Ho S W; O'Connell B C; Kleinman H K; Hoffman M P
PKC and ERK1/2 regulate amylase promoter activity during differentiation of a salivary gland cell line.
Journal of cellular physiology 2000;185(2):215-25.
2000: Powell S K; Rao J; Roque E; Nomizu M; Kuratomi Y; Yamada Y; Kleinman H K
Neural cell response to multiple novel sites on laminin-1.
Journal of neuroscience research 2000;61(3):302-12.
2000: Salcedo R; Ponce M L; Young H A; Wasserman K; Ward J M; Kleinman H K; Oppenheim J J; Murphy W J
Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression.
Blood 2000;96(1):34-40.
2000: Nomizu M; Kuratomi Y; Ponce M L; Song S Y; Miyoshi K; Otaka A; Powell S K; Hoffman M P; Kleinman H K; Yamada Y
Cell adhesive sequences in mouse laminin beta1 chain.
Archives of biochemistry and biophysics 2000;378(2):311-20.
1999: Gho Y S; Kleinman H K; Sosne G
Angiogenic activity of human soluble intercellular adhesion molecule-1.
Cancer research 1999;59(20):5128-32.
1999: Jacob K; Webber M; Benayahu D; Kleinman H K
Osteonectin promotes prostate cancer cell migration and invasion: a possible mechanism for metastasis to bone.
Cancer research 1999;59(17):4453-7.
1999: Malinda K M; Sidhu G S; Mani H; Banaudha K; Maheshwari R K; Goldstein A L; Kleinman H K
Thymosin beta4 accelerates wound healing.
The Journal of investigative dermatology 1999;113(3):364-8.
1999: Malinda K M; Ponce L; Kleinman H K; Shackelton L M; Millis A J
Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells.
Experimental cell research 1999;250(1):168-73.
1999: Boykins R A; Mahieux R; Shankavaram U T; Gho Y S; Lee S F; Hewlett I K; Wahl L M; Kleinman H K; Brady J N; Yamada K M; Dhawan S
Cutting edge: a short polypeptide domain of HIV-1-Tat protein mediates pathogenesis.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):15-20.
1999: Kuratomi Y; Nomizu M; Nielsen P K; Tanaka K; Song S Y; Kleinman H K; Yamada Y
Identification of metastasis-promoting sequences in the mouse laminin alpha 1 chain.
Experimental cell research 1999;249(2):386-95.
1999: Cid M C; Hernández-Rodríguez J; Robert J; del Río A; Casademont J; Coll-Vinent B; Grau J M; Kleinman H K; Urbano-Márquez A; Cardellach F
Interferon-alpha may exacerbate cryoblobulinemia-related ischemic manifestations: an adverse effect potentially related to its anti-angiogenic activity.
Arthritis and rheumatism 1999;42(5):1051-5.
1999: Salcedo R; Wasserman K; Young H A; Grimm M C; Howard O M; Anver M R; Kleinman H K; Murphy W J; Oppenheim J J
Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha.
The American journal of pathology 1999;154(4):1125-35.
1999: Ponce M L; Nomizu M; Delgado M C; Kuratomi Y; Hoffman M P; Powell S; Yamada Y; Kleinman H K; Malinda K M
Identification of endothelial cell binding sites on the laminin gamma 1 chain.
Circulation research 1999;84(6):688-94.
1999: Malinda K M; Nomizu M; Chung M; Delgado M; Kuratomi Y; Yamada Y; Kleinman H K; Ponce M L
Identification of laminin alpha1 and beta1 chain peptides active for endothelial cell adhesion, tube formation, and aortic sprouting.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(1):53-62.
1998: Zheng C; Hoffman M P; McMillan T; Kleinman H K; O'Connell B C
Growth factor regulation of the amylase promoter in a differentiating salivary acinar cell line.
Journal of cellular physiology 1998;177(4):628-35.
1998: Nomizu M; Kuratomi Y; Malinda K M; Song S Y; Miyoshi K; Otaka A; Powell S K; Hoffman M P; Kleinman H K; Yamada Y
Cell binding sequences in mouse laminin alpha1 chain.
The Journal of biological chemistry 1998;273(49):32491-9.
1998: Powell S K; Williams C C; Nomizu M; Yamada Y; Kleinman H K
Laminin-like proteins are differentially regulated during cerebellar development and stimulate granule cell neurite outgrowth in vitro.
Journal of neuroscience research 1998;54(2):233-47.
1998: Hoffman M P; Nomizu M; Roque E; Lee S; Jung D W; Yamada Y; Kleinman H K
Laminin-1 and laminin-2 G-domain synthetic peptides bind syndecan-1 and are involved in acinar formation of a human submandibular gland cell line.
The Journal of biological chemistry 1998;273(44):28633-41.
1998: Kim W H; Nomizu M; Song S Y; Tanaka K; Kuratomi Y; Kleinman H K; Yamada Y
Laminin-alpha1-chain sequence Leu-Gln-Val-Gln-Leu-Ser-Ile-Arg (LQVQLSIR) enhances murine melanoma cell metastases.
International journal of cancer. Journal international du cancer 1998;77(4):632-9.
1998: Zukowska-Grojec Z; Karwatowska-Prokopczuk E; Rose W; Rone J; Movafagh S; Ji H; Yeh Y; Chen W T; Kleinman H K; Grouzmann E; Grant D S
Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium.
Circulation research 1998;83(2):187-95.
1998: Montesano R; Soriano J V; Malinda K M; Ponce M L; Bafico A; Kleinman H K; Bottaro D P; Aaronson S A
Differential effects of hepatocyte growth factor isoforms on epithelial and endothelial tubulogenesis.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(5):355-65.
1998: Thaloor D; Singh A K; Sidhu G S; Prasad P V; Kleinman H K; Maheshwari R K
Inhibition of angiogenic differentiation of human umbilical vein endothelial cells by curcumin.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(4):305-12.
1998: Malinda K M; Sidhu G S; Banaudha K K; Gaddipati J P; Maheshwari R K; Goldstein A L; Kleinman H K
Thymosin alpha 1 stimulates endothelial cell migration, angiogenesis, and wound healing.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):1001-6.
1997: Nomizu M; Kuratomi Y; Song S Y; Ponce M L; Hoffman M P; Powell S K; Miyoshi K; Otaka A; Kleinman H K; Yamada Y
Identification of cell binding sequences in mouse laminin gamma1 chain by systematic peptide screening.
The Journal of biological chemistry 1997;272(51):32198-205.
1997: Lee S K; Malpeli M; Cancedda R; Utani A; Yamada Y; Kleinman H K
Laminin chain expression by chick chondrocytes and mouse cartilaginous tissues in vivo and in vitro.
Experimental cell research 1997;236(1):212-22.
1997: Malinda K M; Goldstein A L; Kleinman H K
Thymosin beta 4 stimulates directional migration of human umbilical vein endothelial cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(6):474-81.
1997: Song S Y; Nomizu M; Yamada Y; Kleinman H K
Liver metastasis formation by laminin-1 peptide (LQVQLSIR)-adhesion selected B16-F10 melanoma cells.
International journal of cancer. Journal international du cancer 1997;71(3):436-41.
1996: Nomizu M; Song S Y; Kuratomi Y; Tanaka M; Kim W H; Kleinman H K; Yamada Y
Active peptides from the carboxyl-terminal globular domain of laminin alpha2 and Drosophila alpha chains.
FEBS letters 1996;396(1):37-42.
1996: Richard B L; Nomizu M; Yamada Y; Kleinman H K
Identification of synthetic peptides derived from laminin alpha1 and alpha2 chains with cell type specificity for neurite outgrowth.
Experimental cell research 1996;228(1):98-105.
1996: Malinda K M; Kleinman H K
The laminins.
The international journal of biochemistry & cell biology 1996;28(9):957-9.
1996: Hoffman M P; Kibbey M C; Letterio J J; Kleinman H K
Role of laminin-1 and TGF-beta 3 in acinar differentiation of a human submandibular gland cell line (HSG).
Journal of cell science 1996;109 ( Pt 8)():2013-21.
1995: Grant D S; Kinsella J L; Kibbey M C; LaFlamme S; Burbelo P D; Goldstein A L; Kleinman H K
Matrigel induces thymosin beta 4 gene in differentiating endothelial cells.
Journal of cell science 1995;108 ( Pt 12)():3685-94.
1995: Kibbey M C; Johnson B; Petryshyn R; Jucker M; Kleinman H K
A 110-kD nuclear shuttling protein, nucleolin, binds to the neurite-promoting IKVAV site of laminin-1.
Journal of neuroscience research 1995;42(3):314-22.
1995: Schnaper H W; Barnathan E S; Mazar A; Maheshwari S; Ellis S; Cortez S L; Baricos W H; Kleinman H K
Plasminogen activators augment endothelial cell organization in vitro by two distinct pathways.
Journal of cellular physiology 1995;165(1):107-18.
1995: Weeks B S; Lieberman D M; Johnson B; Roque E; Green M; Loewenstein P; Oldfield E H; Kleinman H K
Neurotoxicity of the human immunodeficiency virus type 1 tat transactivator to PC12 cells requires the Tat amino acid 49-58 basic domain.
Journal of neuroscience research 1995;42(1):34-40.
1995: Nomizu M; Kim W H; Yamamura K; Utani A; Song S Y; Otaka A; Roller P P; Kleinman H K; Yamada Y
Identification of cell binding sites in the laminin alpha 1 chain carboxyl-terminal globular domain by systematic screening of synthetic peptides.
The Journal of biological chemistry 1995;270(35):20583-90.
1995: Nomizu M; Weeks B S; Weston C A; Kim W H; Kleinman H K; Yamada Y
Structure-activity study of a laminin alpha 1 chain active peptide segment Ile-Lys-Val-Ala-Val (IKVAV).
FEBS letters 1995;365(2-3):227-31.
1995: Corcoran M L; Kibbey M C; Kleinman H K; Wahl L M
Laminin SIKVAV peptide induction of monocyte/macrophage prostaglandin E2 and matrix metalloproteinases.
The Journal of biological chemistry 1995;270(18):10365-8.
1995: Morales D E; McGowan K A; Grant D S; Maheshwari S; Bhartiya D; Cid M C; Kleinman H K; Schnaper H W
Estrogen promotes angiogenic activity in human umbilical vein endothelial cells in vitro and in a murine model.
Circulation 1995;91(3):755-63.
1994: Kim W H; Schnaper H W; Nomizu M; Yamada Y; Kleinman H K
Apoptosis in human fibrosarcoma cells is induced by a multimeric synthetic Tyr-Ile-Gly-Ser-Arg (YIGSR)-containing polypeptide from laminin.
Cancer research 1994;54(18):5005-10.
1994: Kibbey M C; Corcoran M L; Wahl L M; Kleinman H K
Laminin SIKVAV peptide-induced angiogenesis in vivo is potentiated by neutrophils.
Journal of cellular physiology 1994;160(1):185-93.
1994: Burbelo P D; Gabriel G C; Kibbey M C; Yamada Y; Kleinman H K; Weeks B S
LZIP-1 and LZIP-2: two novel members of the bZIP family.
Gene 1994;139(2):241-5.
1994: Weeks B S; Holloway E; Klotman P E; Akiyama S K; Schnaper H W; Kleinman H K
12-O-tetradecanoylphorbol 13-acetate stimulates human T-lymphocyte adherence to the fibronectin RGD domain and the laminin IKVAV domain.
Cellular immunology 1994;153(1):94-104.
1994: Kim W H; Jun S H; Kibbey M C; Thompson E W; Kleinman H K
Expression of beta 1 integrin in laminin-adhesion-selected human colon cancer cell lines of varying tumorigenicity.
Invasion & metastasis 1994;14(1-6):147-55.
1994: Kibbey M C; Yamamura K; Jun S H; Grant D S; Kleinman H K
Enhancement of tumor growth by basement membrane: modulation of growth and angiogenesis by laminin-derived synthetic peptides.
Cancer treatment and research 1994;71():267-75.
1993: Weeks B S; Schnaper H W; Handy M; Holloway E; Kleinman H K
Human T lymphocytes synthesize the 92 kDa type IV collagenase (gelatinase B).
Journal of cellular physiology 1993;157(3):644-9.
1993: Kibbey M C; Jucker M; Weeks B S; Neve R L; Van Nostrand W E; Kleinman H K
beta-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):10150-3.
1993: Yamamura K; Kibbey M C; Jun S H; Kleinman H K
Effect of Matrigel and laminin peptide YIGSR on tumor growth and metastasis.
Seminars in cancer biology 1993;4(4):259-65.
1993: Nomizu M; Yamamura K; Kleinman H K; Yamada Y
Multimeric forms of Tyr-Ile-Gly-Ser-Arg (YIGSR) peptide enhance the inhibition of tumor growth and metastasis.
Cancer research 1993;53(15):3459-61.
1993: Ren K; Kibbey M C; Kleinman H K; Ruda M A
110/140 laminin-binding protein immunoreactivity in spinal dorsal root ganglia: a capsaicin-insensitive reduction induced by constriction injury of the sciatic nerve in rats.
Journal of neuroscience research 1993;35(3):227-36.
1993: Weeks B S; Klotman M E; Holloway E; Stetler-Stevenson W G; Kleinman H K; Klotman P E
HIV-1 infection stimulates T cell invasiveness and synthesis of the 92-kDa type IV collagenase.
AIDS research and human retroviruses 1993;9(6):513-8.
1993: Weeks B S; Desai K; Loewenstein P M; Klotman M E; Klotman P E; Green M; Kleinman H K
Identification of a novel cell attachment domain in the HIV-1 Tat protein and its 90-kDa cell surface binding protein.
The Journal of biological chemistry 1993;268(7):5279-84.
1993: Royce L S; Kibbey M C; Mertz P; Kleinman H K; Baum B J
Human neoplastic submandibular intercalated duct cells express an acinar phenotype when cultured on a basement membrane matrix.
Differentiation; research in biological diversity 1993;52(3):247-55.
1993: Grant D S; Kleinman H K; Goldberg I D; Bhargava M M; Nickoloff B J; Kinsella J L; Polverini P; Rosen E M
Scatter factor induces blood vessel formation in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1937-41.
1993: Yamamura K; Kibbey M C; Kleinman H K
Melanoma cells selected for adhesion to laminin peptides have different malignant properties.
Cancer research 1993;53(2):423-8.
1993: Kleinman H K; Weeks B S; Schnaper H W; Kibbey M C; Yamamura K; Grant D S
The laminins: a family of basement membrane glycoproteins important in cell differentiation and tumor metastases.
Vitamins and hormones 1993;47():161-86.
1993: Rosen E M; Grant D S; Kleinman H K; Goldberg I D; Bhargava M M; Nickoloff B J; Kinsella J L; Polverini P
Scatter factor (hepatocyte growth factor) is a potent angiogenesis factor in vivo.
Symposia of the Society for Experimental Biology 1993;47():227-34.
1992: Paralkar V M; Weeks B S; Yu Y M; Kleinman H K; Reddi A H
Recombinant human bone morphogenetic protein 2B stimulates PC12 cell differentiation: potentiation and binding to type IV collagen.
The Journal of cell biology 1992;119(6):1721-8.
1992: Grant D S; Kinsella J L; Fridman R; Auerbach R; Piasecki B A; Yamada Y; Zain M; Kleinman H K
Interaction of endothelial cells with a laminin A chain peptide (SIKVAV) in vitro and induction of angiogenic behavior in vivo.
Journal of cellular physiology 1992;153(3):614-25.
1992: Kibbey M C; Grant D S; Kleinman H K
Role of the SIKVAV site of laminin in promotion of angiogenesis and tumor growth: an in vivo Matrigel model.
Journal of the National Cancer Institute 1992;84(21):1633-8.
1992: Yamada Y; Kleinman H K
Functional domains of cell adhesion molecules.
Current opinion in cell biology 1992;4(5):819-23.
1992: Fridman R; Sweeney T M; Zain M; Martin G R; Kleinman H K
Malignant transformation of NIH-3T3 cells after subcutaneous co-injection with a reconstituted basement membrane (matrigel).
International journal of cancer. Journal international du cancer 1992;51(5):740-4.
1992: Furtado G C; Slowik M; Kleinman H K; Joiner K A
Laminin enhances binding of Toxoplasma gondii tachyzoites to J774 murine macrophage cells.
Infection and immunity 1992;60(6):2337-42.
1992: Kibbey M C; Royce L S; Dym M; Baum B J; Kleinman H K
Glandular-like morphogenesis of the human submandibular tumor cell line A253 on basement membrane components.
Experimental cell research 1992;198(2):343-51.
1992: Royce L S; Martin G R; Kleinman H K
Induction of an invasive phenotype in benign tumor cells with a laminin A-chain synthetic peptide.
Invasion & metastasis 1992;12(3-4):149-55.
1991: Kleinman H K; Weeks B S; Cannon F B; Sweeney T M; Sephel G C; Clement B; Zain M; Olson M O; Jucker M; Burrous B A
Identification of a 110-kDa nonintegrin cell surface laminin-binding protein which recognizes an A chain neurite-promoting peptide.
Archives of biochemistry and biophysics 1991;290(2):320-5.
1991: Weeks B S; Kopp J B; Horikoshi S; Cannon F B; Garrett M; Kleinman H K; Klotman P E
Adult and fetal human mesangial cells interact with specific laminin domains.
The American journal of physiology 1991;261(4 Pt 2):F688-95.
1991: Sweeney T M; Kibbey M C; Zain M; Fridman R; Kleinman H K
Basement membrane and the SIKVAV laminin-derived peptide promote tumor growth and metastases.
Cancer metastasis reviews 1991;10(3):245-54.
1991: Weeks B S; Klotman M E; Dhawan S; Kibbey M; Rappaport J; Kleinman H K; Yamada K M; Klotman P E
HIV-1 infection of human T lymphocytes results in enhanced alpha 5 beta 1 integrin expression.
The Journal of cell biology 1991;114(4):847-53.
1991: Fridman R; Kibbey M C; Royce L S; Zain M; Sweeney M; Jicha D L; Yannelli J R; Martin G R; Kleinman H K
Enhanced tumor growth of both primary and established human and murine tumor cells in athymic mice after coinjection with Matrigel.
Journal of the National Cancer Institute 1991;83(11):769-74.
1991: Grant D S; Lelkes P I; Fukuda K; Kleinman H K
Intracellular mechanisms involved in basement membrane induced blood vessel differentiation in vitro.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1991;27A(4):327-36.
1991: Weeks B S; Papadopoulos V; Dym M; Kleinman H K
cAMP promotes branching of laminin-induced neuronal processes.
Journal of cellular physiology 1991;147(1):62-7.
1991: Tashiro K; Sephel G C; Greatorex D; Sasaki M; Shirashi N; Martin G R; Kleinman H K; Yamada Y
The RGD containing site of the mouse laminin A chain is active for cell attachment, spreading, migration and neurite outgrowth.
Journal of cellular physiology 1991;146(3):451-9.
1991: Maheshwari R K; Srikantan V; Bhartiya D; Kleinman H K; Grant D S
Differential effects of interferon gamma and alpha on in vitro model of angiogenesis.
Journal of cellular physiology 1991;146(1):164-9.
1991: Rosen E M; Grant D; Kleinman H; Jaken S; Donovan M A; Setter E; Luckett P M; Carley W; Bhargava M; Goldberg I D
Scatter factor stimulates migration of vascular endothelium and capillary-like tube formation.
EXS 1991;59():76-88.
1990: Weeks B S; DiSalvo J; Kleinman H K
Laminin-mediated process formation in neuronal cells involves protein dephosphorylation.
Journal of neuroscience research 1990;27(3):418-26.
1990: Paralkar V M; Nandedkar A K; Pointer R H; Kleinman H K; Reddi A H
Interaction of osteogenin, a heparin binding bone morphogenetic protein, with type IV collagen.
The Journal of biological chemistry 1990;265(28):17281-4.
1990: Vukicevic S; Luyten F P; Kleinman H K; Reddi A H
Differentiation of canalicular cell processes in bone cells by basement membrane matrix components: regulation by discrete domains of laminin.
Cell 1990;63(2):437-45.
1990: Kanemoto T; Reich R; Royce L; Greatorex D; Adler S H; Shiraishi N; Martin G R; Yamada Y; Kleinman H K
Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(6):2279-83.
1990: Clément B; Segui-Real B; Savagner P; Kleinman H K; Yamada Y
Hepatocyte attachment to laminin is mediated through multiple receptors.
The Journal of cell biology 1990;110(1):185-92.
1990: Grant D S; Kleinman H K; Martin G R
The role of basement membranes in vascular development.
Annals of the New York Academy of Sciences 1990;588():61-72.
1990: Kleinman H K; Sephel G C; Tashiro K; Weeks B S; Burrous B A; Adler S H; Yamada Y; Martin G R
Laminin in neuronal development.
Annals of the New York Academy of Sciences 1990;580():302-10.
1989: Kleinman H K; Weeks B S
Laminin: structure, functions and receptors.
Current opinion in cell biology 1989;1(5):964-7.
1989: Tashiro K; Sephel G C; Weeks B; Sasaki M; Martin G R; Kleinman H K; Yamada Y
A synthetic peptide containing the IKVAV sequence from the A chain of laminin mediates cell attachment, migration, and neurite outgrowth.
The Journal of biological chemistry 1989;264(27):16174-82.
1989: Grant D S; Tashiro K; Segui-Real B; Yamada Y; Martin G R; Kleinman H K
Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro.
Cell 1989;58(5):933-43.
1989: Sephel G C; Tashiro K; Sasaki M; Kandel S; Yamada Y; Kleinman H K
A laminin-pepsin fragment with cell attachment and neurite outgrowth activity at distinct sites.
Developmental biology 1989;135(1):172-81.
1989: Sephel G C; Tashiro K I; Sasaki M; Greatorex D; Martin G R; Yamada Y; Kleinman H K
Laminin A chain synthetic peptide which supports neurite outgrowth.
Biochemical and biophysical research communications 1989;162(2):821-9.
1989: Kleinman H K; Graf J; Iwamoto Y; Sasaki M; Schasteen C S; Yamada Y; Martin G R; Robey F A
Identification of a second active site in laminin for promotion of cell adhesion and migration and inhibition of in vivo melanoma lung colonization.
Archives of biochemistry and biophysics 1989;272(1):39-45.
1989: Sephel G C; Burrous B A; Kleinman H K
Laminin neural activity and binding proteins.
Developmental neuroscience 1989;11(4-5):313-31.
1988: Sasaki M; Kleinman H K; Huber H; Deutzmann R; Yamada Y
Laminin, a multidomain protein. The A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains.
The Journal of biological chemistry 1988;263(32):16536-44.
1988: Luckenbill-Edds L; Kleinman H K
Effect of laminin and cytoskeletal agents on neurite formation by NG108-15 cells.
Journal of neuroscience research 1988;19(2):219-29.
1988: Iwamoto Y; Graf J; Sasaki M; Kleinman H K; Greatorex D R; Martin G R; Robey F A; Yamada Y
Synthetic pentapeptide from the B1 chain of laminin promotes B16F10 melanoma cell migration.
Journal of cellular physiology 1988;134(2):287-91.
1988: Kleinman H K; Ogle R C; Cannon F B; Little C D; Sweeney T M; Luckenbill-Edds L
Laminin receptors for neurite formation.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):1282-6.
1987: Graf J; Ogle R C; Robey F A; Sasaki M; Martin G R; Yamada Y; Kleinman H K
A pentapeptide from the laminin B1 chain mediates cell adhesion and binds the 67,000 laminin receptor.
Biochemistry 1987;26(22):6896-900.
1987: Iwamoto Y; Robey F A; Graf J; Sasaki M; Kleinman H K; Yamada Y; Martin G R
YIGSR, a synthetic laminin pentapeptide, inhibits experimental metastasis formation.
Science (New York, N.Y.) 1987;238(4830):1132-4.
1987: Kleinman H K; Luckenbill-Edds L; Cannon F W; Sephel G C
Use of extracellular matrix components for cell culture.
Analytical biochemistry 1987;166(1):1-13.
1987: Kleinman H K; Graf J; Iwamoto Y; Kitten G T; Ogle R C; Sasaki M; Yamada Y; Martin G R; Luckenbill-Edds L
Role of basement membranes in cell differentiation.
Annals of the New York Academy of Sciences 1987;513():134-45.

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