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Joel Kleinman

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William C Kreisl; Francis J McMahon; Cheryl L Morse; Victor W Pike; Sami S Zoghbi; Winston Corona; Christina S Hines; Thomas Hyde; Chul Hyoung Lyoo; Robert B Innis; Kimberly J Jenko; Joel E Kleinman
A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation.
Kimberly J Jenko; Sami S Zoghbi; Kacey B Anderson; Amy Deep-Soboslay; Ioline D Henter; Jussi Hirvonen; Thomas M Hyde; Robert B Innis; Joel E Kleinman
Binding of a tritiated inverse agonist to cannabinoid CB1 receptors is increased in patients with schizophrenia.
Amanda J Law; Barbara K Lipska; Patricio O'Donnell; Francesco Papaleo; Patrick Piantadosi; Yoshitatsu Sei; Richard E Straub; Craig J Thomas; Radhakrishna Vakkalanka; Yanhong Wang; Aaron D Besterman; Paul J Harrison; Wenwei Huang; Thomas M Hyde; Joel E Kleinman; Daniel R Weinberger
Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy.

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All Publications

2013: William C Kreisl; Francis J McMahon; Cheryl L Morse; Victor W Pike; Sami S Zoghbi; Winston Corona; Christina S Hines; Thomas Hyde; Chul Hyoung Lyoo; Robert B Innis; Kimberly J Jenko; Joel E Kleinman
A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013;33(1):53-8.
2012: Kimberly J Jenko; Sami S Zoghbi; Kacey B Anderson; Amy Deep-Soboslay; Ioline D Henter; Jussi Hirvonen; Thomas M Hyde; Robert B Innis; Joel E Kleinman
Binding of a tritiated inverse agonist to cannabinoid CB1 receptors is increased in patients with schizophrenia.
Schizophrenia research 2012;141(2-3):185-8.
2012: Amanda J Law; Barbara K Lipska; Patricio O'Donnell; Francesco Papaleo; Patrick Piantadosi; Yoshitatsu Sei; Richard E Straub; Craig J Thomas; Radhakrishna Vakkalanka; Yanhong Wang; Aaron D Besterman; Paul J Harrison; Wenwei Huang; Thomas M Hyde; Joel E Kleinman; Daniel R Weinberger
Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(30):12165-70.
2012: Ran Tao; Daniel R Weinberger; Tianzhang Ye; Mary M Herman; Joel E Kleinman; Chao Li; Barbara K Lipska; Erin N Newburn; Thomas M Hyde
Transcript-specific associations of SLC12A5 (KCC2) in human prefrontal cortex with development, schizophrenia, and affective disorders.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(15):5216-22.
2012: Shusuke Numata; Ran Tao; Daniel R Weinberger; Michael Wininger; Tianzhang Ye; Carlo Colantuoni; Xavier Guitart-Navarro; Thomas M Hyde; Joel E Kleinman; Barbara K Lipska
DNA methylation signatures in development and aging of the human prefrontal cortex.
American journal of human genetics 2012;90(2):260-72.
2012: Lindsay A Bliss; Josh G Chenoweth; Amy Deep-Soboslay; Andrew E Jaffe; Amritha Jaishankar; Joel E Kleinman; Renee F Ren-Patterson; Malik R Sams; Thomas M Hyde
Use of postmortem human dura mater and scalp for deriving human fibroblast cultures.
PloS one 2012;7(9):e45282.
2011: Carlo Colantuoni; ELIZABETH COLANTUONI; Abdel G Elkahloun; Mary M Herman; Thomas M Hyde; Jeffrey T Leek; Barbara K Lipska; Ran Tao; Daniel R Weinberger; Tianzhang Ye; Joel E Kleinman
Temporal dynamics and genetic control of transcription in the human prefrontal cortex.
Nature 2011;478(7370):519-23.
2011: Thomas M Hyde; Towhid Ali; Llewellyn B Bigelow; Carlo Colantuoni; Mary M Herman; Amanda J Law; Barbara K Lipska; Shiny V Mathew; Ochuko E Metitiri; Richard E Straub; Daniel R Weinberger; Tianzhang Ye; Joel E Kleinman
Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(30):11088-95.
2011: Fengyu Zhang; Qiang Chen; Tianzhang Ye; Barbara K Lipska; Richard E Straub; Radhakrishna Vakkalanka; Dan Rujescu; David St Clair; Thomas M Hyde; Llewellyn B Bigelow; Joel E Kleinman; Daniel R Weinberger
Evidence of sex-modulated association of ZNF804A with schizophrenia.
Biological psychiatry 2011;69(10):914-7.
2011: Joel E Kleinman
Genetic variation in PCLO is associated with prefrontal cortex expression and bipolar disorder.
Biological psychiatry 2011;69(4):298.
2011: Joel E Kleinman; Amanda J Law; Barbara K Lipska; Thomas M Hyde; Justin K Ellis; Paul J Harrison; Daniel R Weinberger
Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains.
Biological psychiatry 2011;69(2):140-5.
2011: Amy Deep-Soboslay; Francine M Benes; Vahram Haroutunian; Justin K Ellis; Joel E Kleinman; Thomas M Hyde
Psychiatric brain banking: three perspectives on current trends and future directions.
Biological psychiatry 2011;69(2):104-12.
2010: Kristin L Bigos; Venkata S Mattay; Joseph Callicott; Richard E Straub; Radhakrishna Vakkalanka; Bhaskar S Kolachana; Thomas M Hyde; Barbara K Lipska; Joel E Kleinman; Daniel R Weinberger
Genetic variation in CACNA1C affects brain circuitries related to mental illness.
Archives of general psychiatry 2010;67(9):939-45.
2010: Wee-Tin Kao; Yanhong Wang; Joel E Kleinman; Barbara K Lipska; Thomas M Hyde; Daniel R Weinberger; Amanda J Law
Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(35):15619-24.
2010: Heike Tost; Barbara K Lipska; Radhakrishna Vakkalanka; Herve Lemaitre; Joseph Callicott; Venkata S Mattay; Joel E Kleinman; Stefano Marenco; Daniel R Weinberger
No effect of a common allelic variant in the reelin gene on intermediate phenotype measures of brain structure, brain function, and gene expression.
Biological psychiatry 2010;68(1):105-7.
2010: Herve Lemaitre; Venkata S Mattay; Fabio Sambataro; Beth A Verchinski; Richard E Straub; Joseph Callicott; Raja Kittappa; Thomas M Hyde; Barbara K Lipska; Joel E Kleinman; Ronald McKay; Daniel R Weinberger
Genetic variation in FGF20 modulates hippocampal biology.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(17):5992-7.
2009: Kenji Nakata; Barbara K Lipska; Thomas M Hyde; Tianzhang Ye; Erin N Newburn; Yukitaka Morita; Radhakrishna Vakkalanka; Maxim Barenboim; Yoshitatsu Sei; Daniel R Weinberger; Joel E Kleinman
DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(37):15873-8.
2009: Stephen J Huffaker; Jingshan Chen; Kristin K Nicodemus; Fabio Sambataro; Feng Yang; Venkata S Mattay; Barbara K Lipska; Thomas M Hyde; Jian Song; Dan Rujescu; Ina Giegling; Karine Mayilyan; Morgan J Proust; Armen Soghoyan; Grazia Caforio; Joseph Callicott; Alessandro Bertolino; Andreas Meyer-Lindenberg; Jay Chang; Yuanyuan Ji; Michael Egan; Terry Goldberg; Joel E Kleinman; Bai Lu; Daniel R Weinberger
A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia.
Nature medicine 2009;15(5):509-18.
2008: Amy Deep-Soboslay; Bianca Iglesias; Thomas M Hyde; Llewelyn B Bigelow; Vesna Imamovic; Mary M Herman; Joel E Kleinman
Evaluation of tissue collection for postmortem studies of bipolar disorder.
Bipolar disorders 2008;10(7):822-8.
2008: Subroto Ghose; Jeremy M Crook; Cynthia L Bartus; Thomas G Sherman; Mary M Herman; Thomas M Hyde; Joel E Kleinman; Mayada Akil
Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia.
The International journal of neuroscience 2008;118(11):1609-27.
2008: Leah J Sartorius; Daniel R Weinberger; Thomas M Hyde; Paul J Harrison; Joel E Kleinman; Barbara K Lipska
Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(11):2626-34.
2008: Carlo Colantuoni; Thomas M Hyde; Shruti Mitkus; Andrew Joseph; Leah Sartorius; Claudia Aguirre; Johanna Creswell; ELIZABETH COLANTUONI; Amy Deep-Soboslay; Mary M Herman; Barbara K Lipska; Daniel R Weinberger; Joel E Kleinman
Age-related changes in the expression of schizophrenia susceptibility genes in the human prefrontal cortex.
Brain structure & function 2008;213(1-2):255-71.
2008: Cynthia Shannon Weickert; Ana L Miranda-Angulo; Jenny Wong; William R Perlman; Sarah E Ward; Vakkalanka Radhakrishna; Richard E Straub; Daniel R Weinberger; Joel E Kleinman
Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia.
Human molecular genetics 2008;17(15):2293-309.
2008: D Montague; Cynthia Shannon Weickert; Eva Tomaskovic-Crook; Debora A Rothmond; Joel E Kleinman; David Rubinow
Oestrogen receptor alpha localisation in the prefrontal cortex of three mammalian species.
Journal of neuroendocrinology 2008;20(7):893-903.
2008: Nader D Halim; Barbara K Lipska; Thomas M Hyde; Amy Deep-Soboslay; E Michael Saylor; Mary M Herman; Jay Thakar; Ajay Verma; Joel E Kleinman
Increased lactate levels and reduced pH in postmortem brains of schizophrenics: medication confounds.
Journal of neuroscience methods 2008;169(1):208-13.
2008: Elin Lehrmann; Zoan R Afanador; Amy Deep-Soboslay; Gloria Gallegos; William D Darwin; Ross H Lowe; Allan J Barnes; Marilyn A Huestis; Jean L Cadet; Mary M Herman; Thomas M Hyde; Joel E Kleinman; William J Freed
Postmortem diagnosis and toxicological validation of illicit substance use.
Addiction biology 2008;13(1):105-17.
2008: Shruti N Mitkus; Thomas M Hyde; Radhakrishna Vakkalanka; Bhaskar S Kolachana; Daniel R Weinberger; Joel E Kleinman; Barbara K Lipska
Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia.
Schizophrenia research 2008;98(1-3):129-38.
2008: Cynthia Shannon Weickert; Debora A Rothmond; Thomas M Hyde; Joel E Kleinman; Richard E Straub
Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients.
Schizophrenia research 2008;98(1-3):105-10.
2007: Shiny V Mathew; Amanda J Law; Barbara K Lipska; Martha I Dávila-García; Eduardo D Zamora; Shruti N Mitkus; Radhakrishna Vakkalanka; Richard E Straub; Daniel R Weinberger; Joel E Kleinman; Thomas M Hyde
Alpha7 nicotinic acetylcholine receptor mRNA expression and binding in postmortem human brain are associated with genetic variation in neuregulin 1.
Human molecular genetics 2007;16(23):2921-32.
2007: Richard E Straub; Barbara K Lipska; Michael Egan; Terry Goldberg; Joseph Callicott; M B Mayhew; Radhakrishna Vakkalanka; Bhaskar S Kolachana; Joel E Kleinman; Daniel R Weinberger
Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression.
Molecular psychiatry 2007;12(9):854-69.
2007: Elizabeth Tunbridge; Cynthia Shannon Weickert; Joel E Kleinman; Mary M Herman; J Chen; Bhaskar S Kolachana; Paul J Harrison; Daniel R Weinberger
Catechol-o-methyltransferase enzyme activity and protein expression in human prefrontal cortex across the postnatal lifespan.
Cerebral cortex (New York, N.Y. : 1991) 2007;17(5):1206-12.
2007: Andreas Meyer-Lindenberg; Richard E Straub; Barbara K Lipska; Beth A Verchinski; Terry Goldberg; Joseph Callicott; Michael Egan; Stephen S Huffaker; Venkata S Mattay; Bhaskar S Kolachana; Joel E Kleinman; Daniel R Weinberger
Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition.
The Journal of clinical investigation 2007;117(3):672-82.
2007: William R Perlman; Maree Webster; Mary M Herman; Joel E Kleinman; Cynthia Shannon Weickert
Age-related differences in glucocorticoid receptor mRNA levels in the human brain.
Neurobiology of aging 2007;28(3):447-58.
2007: Cynthia Shannon Weickert; Maree Webster; P Gondipalli; Debora A Rothmond; Robert J Fatula; Mary M Herman; Joel E Kleinman; Mayada Akil
Postnatal alterations in dopaminergic markers in the human prefrontal cortex.
Neuroscience 2007;144(3):1109-19.
2007: Amanda J Law; Joel E Kleinman; Daniel R Weinberger; Cynthia Shannon Weickert
Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia.
Human molecular genetics 2007;16(2):129-41.
2006: Maree Webster; M M Herman; Joel E Kleinman; Cynthia Shannon Weickert
BDNF and trkB mRNA expression in the hippocampus and temporal cortex during the human lifespan.
Gene expression patterns : GEP 2006;6(8):941-51.
2006: Barbara K Lipska; Amy Deep-Soboslay; Cynthia Shannon Weickert; Thomas M Hyde; Catherine E Martin; Mary M Herman; Joel E Kleinman
Critical factors in gene expression in postmortem human brain: Focus on studies in schizophrenia.
Biological psychiatry 2006;60(6):650-8.
2006: Barbara K Lipska; Shruti N Mitkus; Mark Caruso; Thomas M Hyde; Jingshan Chen; Radhakrishna Vakkalanka; Richard E Straub; Daniel R Weinberger; Joel E Kleinman
RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity.
Human molecular genetics 2006;15(18):2804-12.
2006: Amanda J Law; Barbara K Lipska; Cynthia Shannon Weickert; Thomas M Hyde; Richard E Straub; Ryota Hashimoto; Paul J Harrison; Joel E Kleinman; Daniel R Weinberger
Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(17):6747-52.
2006: Barbara K Lipska; Tricia Peters; Thomas M Hyde; Nader D Halim; Cara Horowitz; Shruti N Mitkus; Cynthia Shannon Weickert; Mitsuyuki Matsumoto; Akira Sawa; Richard E Straub; Radhakrishna Vakkalanka; Mary M Herman; Daniel R Weinberger; Joel E Kleinman
Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs.
Human molecular genetics 2006;15(8):1245-58.
2006: Ross H Lowe; Allan J Barnes; Elin Lehrmann; William J Freed; Joel E Kleinman; Thomas M Hyde; Mary M Herman; Marilyn A Huestis
A validated positive chemical ionization GC/MS method for the identification and quantification of amphetamine, opiates, cocaine, and metabolites in human postmortem brain.
Journal of mass spectrometry : JMS 2006;41(2):175-84.
2006: Elin Lehrmann; Carlo Colantuoni; Amy Deep-Soboslay; Kevin G Becker; Ross Lowe; Marilyn A Huestis; Thomas M Hyde; Joel E Kleinman; William J Freed
Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse.
PloS one 2006;1():e114.
2006: Barbara K Lipska; Shruti N Mitkus; Shiny V Mathew; Robert J Fatula; Thomas M Hyde; Daniel R Weinberger; Joel E Kleinman
Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophrenia.
Dialogues in clinical neuroscience 2006;8(3):353-7.
2006: Sharon L Eastwood; Cynthia Shannon Weickert; Maree Webster; Mary M Herman; Joel E Kleinman; Paul J Harrison
Synaptophysin protein and mRNA expression in the human hippocampal formation from birth to old age.
Hippocampus 2006;16(8):645-54.
2005: William R Perlman; Eva Tomaskovic-Crook; Deidra M Montague; Maree Webster; David Rubinow; Joel E Kleinman; Cynthia Shannon Weickert
Alteration in estrogen receptor alpha mRNA levels in frontal cortex and hippocampus of patients with major mental illness.
Biological psychiatry 2005;58(10):812-24.
2005: Daphne J Holt; Susan E Bachus; Thomas M Hyde; Michael Wittie; Mary M Herman; Mark Vangel; Clifford B Saper; Joel E Kleinman
Reduced density of cholinergic interneurons in the ventral striatum in schizophrenia: an in situ hybridization study.
Biological psychiatry 2005;58(5):408-16.
2005: Mitsuyuki Matsumoto; Senda Beltaifa; Cynthia Shannon Weickert; Mary M Herman; Thomas M Hyde; Richard C Saunders; Barbara K Lipska; Daniel R Weinberger; Joel E Kleinman
A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain.
Brain research. Molecular brain research 2005;138(1):58-69.
2005: Cynthia Shannon Weickert; Davinna L Ligons; T Romanczyk; G Ungaro; Thomas M Hyde; Mary M Herman; Daniel R Weinberger; Joel E Kleinman
Reductions in neurotrophin receptor mRNAs in the prefrontal cortex of patients with schizophrenia.
Molecular psychiatry 2005;10(7):637-50.
2005: Senda Beltaifa; Maree Webster; Davinna L Ligons; Robert J Fatula; Mary M Herman; Joel E Kleinman; Cynthia Shannon Weickert
Discordant changes in cortical TrkC mRNA and protein during the human lifespan.
The European journal of neuroscience 2005;21(9):2433-44.
2005: William R Perlman; Mitsuyuki Matsumoto; Senda Beltaifa; Thomas M Hyde; Richard C Saunders; Maree Webster; David Rubinow; Joel E Kleinman; Cynthia Shannon Weickert
Expression of estrogen receptor alpha exon-deleted mRNA variants in the human and non-human primate frontal cortex.
Neuroscience 2005;134(1):81-95.
2005: Cynthia Shannon Weickert; D A Kittell; Richard C Saunders; Mary M Herman; R A Horlick; Joel E Kleinman; Thomas M Hyde
Basic fibroblast growth factor and fibroblast growth factor receptor-1 in the human hippocampal formation.
Neuroscience 2005;131(1):219-33.
2005: Amy Deep-Soboslay; Mayada Akil; Catherine E Martin; Llewellyn B Bigelow; Mary M Herman; Thomas M Hyde; Joel E Kleinman
Reliability of psychiatric diagnosis in postmortem research.
Biological psychiatry 2005;57(1):96-101.
2004: William R Perlman; Maree Webster; Joel E Kleinman; Cynthia Shannon Weickert
Reduced glucocorticoid and estrogen receptor alpha messenger ribonucleic acid levels in the amygdala of patients with major mental illness.
Biological psychiatry 2004;56(11):844-52.
2004: Jingshan Chen; Barbara K Lipska; Nader D Halim; Quang D Ma; Mitsuyuki Matsumoto; Samer Melhem; Bhaskar S Kolachana; Thomas M Hyde; Mary M Herman; José A Apud; Michael Egan; Joel E Kleinman; Daniel R Weinberger
Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain.
American journal of human genetics 2004;75(5):807-21.
2004: Amanda J Law; Cynthia Shannon Weickert; Thomas M Hyde; Joel E Kleinman; Paul J Harrison
Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines.
The American journal of psychiatry 2004;161(10):1848-55.
2004: Michael Egan; Richard E Straub; Terry Goldberg; Imtiaz Yakub; Joseph Callicott; Ahmad R Hariri; Venkata S Mattay; Alessandro Bertolino; Thomas M Hyde; Cynthia Shannon Weickert; Mayada Akil; Jeremy Crook; Radhakrishna Vakkalanka; Rishi Balkissoon; Richard A Gibbs; Joel E Kleinman; Daniel R Weinberger
Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12604-9.
2004: William R Perlman; Cynthia Shannon Weickert; Mayada Akil; Joel E Kleinman
Postmortem investigations of the pathophysiology of schizophrenia: the role of susceptibility genes.
Journal of psychiatry & neuroscience : JPN 2004;29(4):287-93.
2004: Cynthia Shannon Weickert; Richard E Straub; Benjamin W McClintock; Mitsuyuki Matsumoto; Ryota Hashimoto; Thomas M Hyde; Mary M Herman; Daniel R Weinberger; Joel E Kleinman
Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain.
Archives of general psychiatry 2004;61(6):544-55.
2004: Marquis P Vawter; Cynthia Shannon Weickert; Erick Ferran; Mitsuyuki Matsumoto; Kevin Overman; Thomas M Hyde; Daniel R Weinberger; William E Bunney; Joel E Kleinman
Gene expression of metabolic enzymes and a protease inhibitor in the prefrontal cortex are decreased in schizophrenia.
Neurochemical research 2004;29(6):1245-55.
2004: R Hashimoto; Richard E Straub; Cynthia Shannon Weickert; Thomas M Hyde; Joel E Kleinman; Daniel R Weinberger
Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia.
Molecular psychiatry 2004;9(3):299-307.
2004: Amy Deep-Soboslay; Catherine E Martin; Joel E Kleinman
The development of a posttraumatic stress disorder brain collection.
Psychiatry 2004;67(4):416-8.
2004: Amanda J Law; Cynthia Shannon Weickert; Thomas M Hyde; Joel E Kleinman; Paul J Harrison
Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain.
Neuroscience 2004;127(1):125-36.
2004: Subroto Ghose; Cynthia Shannon Weickert; Sarah M Colvin; Joseph T Coyle; Mary M Herman; Thomas M Hyde; Joel E Kleinman
Glutamate carboxypeptidase II gene expression in the human frontal and temporal lobe in schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(1):117-25.
2003: Amanda J Law; Cynthia Shannon Weickert; Maree Webster; Mary M Herman; Joel E Kleinman; Paul J Harrison
Changes in NMDA receptor subunit mRNAs and cyclophilin mRNA during development of the human hippocampus.
Annals of the New York Academy of Sciences 2003;1003():426-30.
2003: Amanda J Law; Cynthia Shannon Weickert; Maree Webster; Mary M Herman; Joel E Kleinman; Paul J Harrison
Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation.
The European journal of neuroscience 2003;18(5):1197-205.
2003: Nader D Halim; Cynthia Shannon Weickert; Benjamin W McClintock; Thomas M Hyde; Daniel R Weinberger; Joel E Kleinman; Barbara K Lipska
Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development.
Molecular psychiatry 2003;8(9):797-810.
2003: Elin Lehrmann; Thomas M Hyde; Marquis P Vawter; Kevin G Becker; Joel E Kleinman; William J Freed
The use of microarrays to characterize neuropsychiatric disorders: postmortem studies of substance abuse and schizophrenia.
Current molecular medicine 2003;3(5):437-46.
2003: Mitsuyuki Matsumoto; Cynthia Shannon Weickert; Senda Beltaifa; Bhaskar S Kolachana; Jingshan Chen; Thomas M Hyde; Mary M Herman; Daniel R Weinberger; Joel E Kleinman
Catechol O-methyltransferase (COMT) mRNA expression in the dorsolateral prefrontal cortex of patients with schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(8):1521-30.
2003: Cynthia Shannon Weickert; Thomas M Hyde; Barbara K Lipska; Mary M Herman; Daniel R Weinberger; Joel E Kleinman
Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia.
Molecular psychiatry 2003;8(6):592-610.
2003: Mayada Akil; Bhaskar S Kolachana; Debora A Rothmond; Thomas M Hyde; Daniel R Weinberger; Joel E Kleinman
Catechol-O-methyltransferase genotype and dopamine regulation in the human brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(6):2008-13.
2003: Elin Lehrmann; Jonathan M Oyler; Marquis P Vawter; Thomas M Hyde; Bhaskar S Kolachana; Joel E Kleinman; Marilyn A Huestis; Kevin G Becker; William J Freed
Transcriptional profiling in the human prefrontal cortex: evidence for two activational states associated with cocaine abuse.
The pharmacogenomics journal 2003;3(1):27-40.
2003: Mitsuyuki Matsumoto; Cynthia Shannon Weickert; Mayada Akil; Barbara K Lipska; Thomas M Hyde; Mary M Herman; Joel E Kleinman; Daniel R Weinberger
Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function.
Neuroscience 2003;116(1):127-37.
2002: Marquis P Vawter; Jeremy M Crook; Thomas M Hyde; Joel E Kleinman; Daniel R Weinberger; Kevin G Becker; William J Freed
Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study.
Schizophrenia research 2002;58(1):11-20.
2002: Emad H Hamid; Thomas M Hyde; Michael Egan; Steve S Wolf; Mary M Herman; Charles Nemeroff; Joel E Kleinman
Neurotensin receptor binding abnormalities in the entorhinal cortex in schizophrenia and affective disorders.
Biological psychiatry 2002;51(10):795-800.
2002: Marquis P Vawter; L Thatcher; N Usen; Thomas M Hyde; Joel E Kleinman; William J Freed
Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia.
Molecular psychiatry 2002;7(6):571-8.
2002: T B Romanczyk; Cynthia Shannon Weickert; Maree Webster; Mary M Herman; Mayada Akil; Joel E Kleinman
Alterations in trkB mRNA in the human prefrontal cortex throughout the lifespan.
The European journal of neuroscience 2002;15(2):269-80.
2002: Jeremy M Crook; Mayada Akil; B C W Law; Thomas M Hyde; Joel E Kleinman
Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects.
Molecular psychiatry 2002;7(2):157-64.
2001: Brita Elvevåg; D M Weinstock; Mayada Akil; Joel E Kleinman; Terry Goldberg
A comparison of verbal fluency tasks in schizophrenic patients and normal controls.
Schizophrenia research 2001;51(2-3):119-26.
2001: Ruslan Damadzic; Llewellyn B Bigelow; LS Krimer; D A Goldenson; Richard C Saunders; Joel E Kleinman; Mary M Herman
A quantitative immunohistochemical study of astrocytes in the entorhinal cortex in schizophrenia, bipolar disorder and major depression: absence of significant astrocytosis.
Brain research bulletin 2001;55(5):611-8.
2001: Maree Webster; Cynthia Shannon Weickert; M M Herman; Thomas M Hyde; Joel E Kleinman
Synaptophysin and GAP-43 mRNA levels in the hippocampus of subjects with schizophrenia.
Schizophrenia research 2001;49(1-2):89-98.
2001: J Thomas Noga; Thomas M Hyde; Susan E Bachus; M M Herman; Joel E Kleinman
AMPA receptor binding in the dorsolateral prefrontal cortex of schizophrenics and controls.
Schizophrenia research 2001;48(2-3):361-3.
2001: Cynthia Shannon Weickert; Maree Webster; Thomas M Hyde; Mary M Herman; Susan E Bachus; G Bali; Daniel R Weinberger; Joel E Kleinman
Reduced GAP-43 mRNA in dorsolateral prefrontal cortex of patients with schizophrenia.
Cerebral cortex (New York, N.Y. : 1991) 2001;11(2):136-47.
2000: Marquis P Vawter; William J Freed; Joel E Kleinman
Neuropathology of bipolar disorder.
Biological psychiatry 2000;48(6):486-504.
2000: Cynthia Shannon Weickert; Maree Webster; S M Colvin; Mary M Herman; Thomas M Hyde; Daniel R Weinberger; Joel E Kleinman
Localization of epidermal growth factor receptors and putative neuroblasts in human subependymal zone.
The Journal of comparative neurology 2000;423(3):359-72.
1999: Chris F Spurney; Serapio Baca; A M Murray; george jaskiw; Joel E Kleinman; Thomas M Hyde
Differential effects of haloperidol and clozapine on ionotropic glutamate receptors in rats.
Synapse (New York, N.Y.) 1999;34(4):266-76.
1999: Marquis P Vawter; A L Howard; Thomas M Hyde; Joel E Kleinman; William J Freed
Alterations of hippocampal secreted N-CAM in bipolar disorder and synaptophysin in schizophrenia.
Molecular psychiatry 1999;4(5):467-75.
1999: C E Helmkamp; Llewellyn B Bigelow; J D Paltán-Ortiz; E F Torrey; Joel E Kleinman; Mary M Herman
Evaluation of superior vermal Purkinje cell placement in mental illness.
Biological psychiatry 1999;45(10):1370-5.
1999: Daphne J Holt; Mary M Herman; Thomas M Hyde; Joel E Kleinman; Christopher M Sinton; Dwight C German; Louis B Hersh; Ann M Graybiel; Clifford B Saper
Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia.
Neuroscience 1999;94(1):21-31.
1998: Marquis P Vawter; JJ Hemperly; Thomas M Hyde; Susan E Bachus; Dale VanderPutten; A L Howard; H E Cannon-Spoor; Michael T McCoy; Maree Webster; Joel E Kleinman; William J Freed
VASE-containing N-CAM isoforms are increased in the hippocampus in bipolar disorder but not schizophrenia.
Experimental neurology 1998;154(1):1-11.
1998: Marquis P Vawter; H E Cannon-Spoor; JJ Hemperly; Thomas M Hyde; Dale VanderPutten; Joel E Kleinman; William J Freed
Abnormal expression of cell recognition molecules in schizophrenia.
Experimental neurology 1998;149(2):424-32.
1997: Susan E Bachus; T M Hyde; Mayada Akil; Cynthia Shannon Weickert; Marquis P Vawter; Joel E Kleinman
Neuropathology of suicide. A review and an approach.
Annals of the New York Academy of Sciences 1997;836():201-19.
1997: LS Krimer; Mary M Herman; Richard C Saunders; James C Boyd; Thomas M Hyde; J M Carter; Joel E Kleinman; Daniel R Weinberger
A qualitative and quantitative analysis of the entorhinal cortex in schizophrenia.
Cerebral cortex (New York, N.Y. : 1991) 1997;7(8):732-9.
1997: J Thomas Noga; Thomas M Hyde; M M Herman; Chris F Spurney; Llewellyn B Bigelow; Daniel R Weinberger; Joel E Kleinman
Glutamate receptors in the postmortem striatum of schizophrenic, suicide, and control brains.
Synapse (New York, N.Y.) 1997;27(3):168-76.
1997: Y L Hurd; Mary M Herman; Thomas M Hyde; Llewellyn B Bigelow; Daniel R Weinberger; Joel E Kleinman
Prodynorphin mRNA expression is increased in the patch vs matrix compartment of the caudate nucleus in suicide subjects.
Molecular psychiatry 1997;2(6):495-500.
1997: Susan E Bachus; Thomas M Hyde; Mary M Herman; Michael Egan; Joel E Kleinman
Abnormal cholecystokinin mRNA levels in entorhinal cortex of schizophrenics.
Journal of psychiatric research 1997;31(2):233-56.
1996: Michael B Knable; Thomas M Hyde; A M Murray; M M Herman; Joel E Kleinman
A postmortem study of frontal cortical dopamine D1 receptors in schizophrenics, psychiatric controls, and normal controls.
Biological psychiatry 1996;40(12):1191-9.
1996: S E Bachus; Joel E Kleinman
The neuropathology of schizophrenia.
The Journal of clinical psychiatry 1996;57 Suppl 11():72-83.
1995: A M Murray; Thomas M Hyde; Michael B Knable; M M Herman; L B Bigelow; J M Carter; Daniel R Weinberger; Joel E Kleinman
Distribution of putative D4 dopamine receptors in postmortem striatum from patients with schizophrenia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(3 Pt 2):2186-91.
1995: Thomas M Hyde; Michael Egan; L L Wing; RJ Wyatt; Daniel R Weinberger; Joel E Kleinman
Persistent catalepsy associated with severe dyskinesias in rats treated with chronic injections of haloperidol decanoate.
Psychopharmacology 1995;118(2):142-9.
1995: T M Hyde; Michael Egan; R J Brown; Daniel R Weinberger; Joel E Kleinman
Diurnal variation in tardive dyskinesia.
Psychiatry research 1995;56(1):53-7.
1994: Michael B Knable; Thomas M Hyde; M M Herman; J M Carter; L Bigelow; Joel E Kleinman
Quantitative autoradiography of dopamine-D1 receptors, D2 receptors, and dopamine uptake sites in postmortem striatal specimens from schizophrenic patients.
Biological psychiatry 1994;36(12):827-35.
1994: Michael B Knable; Thomas M Hyde; Michael Egan; M Tosayali; RJ Wyatt; Joel E Kleinman
Quantitative autoradiography of striatal dopamine D1, D2 and re-uptake sites in rats with vacuous chewing movements.
Brain research 1994;646(2):217-22.
1994: Thomas M Hyde; S Nawroz; Terry Goldberg; L B Bigelow; D Strong; J L Ostrem; Daniel R Weinberger; Joel E Kleinman
Is there cognitive decline in schizophrenia? A cross-sectional study.
The British journal of psychiatry : the journal of mental science 1994;164(4):494-500.
1994: D C Ohuoha; Michael B Knable; S S Wolf; Joel E Kleinman; Thomas M Hyde
The subnuclear distribution of 5-HT3 receptors in the human nucleus of the solitary tract and other structures of the caudal medulla.
Brain research 1994;637(1-2):222-6.
1993: Terry Goldberg; James M Gold; R Greenberg; S Griffin; S C Schulz; DAVID PICKAR; Joel E Kleinman; Daniel R Weinberger
Contrasts between patients with affective disorders and patients with schizophrenia on a neuropsychological test battery.
The American journal of psychiatry 1993;150(9):1355-62.
1993: Anissa Abi-Dargham; Marc Laruelle; Barbara K Lipska; george jaskiw; D T Wong; D W Robertson; Daniel R Weinberger; Joel E Kleinman
Serotonin 5-HT3 receptors in schizophrenia: a postmortem study of the amygdala.
Brain research 1993;616(1-2):53-7.
1993: Terry Goldberg; R D Greenberg; S J Griffin; James M Gold; Joel E Kleinman; DAVID PICKAR; S C Schulz; Daniel R Weinberger
The effect of clozapine on cognition and psychiatric symptoms in patients with schizophrenia.
The British journal of psychiatry : the journal of mental science 1993;162():43-8.
1993: Terry Goldberg; T M Hyde; Joel E Kleinman; Daniel R Weinberger
Course of schizophrenia: neuropsychological evidence for a static encephalopathy.
Schizophrenia bulletin 1993;19(4):797-804.
1992: J R Zigun; D G Daniel; Joel E Kleinman; Daniel R Weinberger
Ventricular enlargement in schizophrenia: is there really a gender effect?
Archives of general psychiatry 1992;49(12):995-7.
1992: M F Casanova; M Zito; L Altshuler; Daniel R Weinberger; Joel E Kleinman
Normal nucleolar size of entorhinal cortex cells in schizophrenia.
Psychiatry research 1992;44(1):79-82.
1992: Marc Laruelle; george jaskiw; Barbara K Lipska; Bhaskar S Kolachana; M F Casanova; Joel E Kleinman; Daniel R Weinberger
D1 and D2 receptor modulation in rat striatum and nucleus accumbens after subchronic and chronic haloperidol treatment.
Brain research 1992;575(1):47-56.
1992: M F Casanova; S O Comparini; R W Kim; Joel E Kleinman
Staining intensity of brain iron in patients with schizophrenia: a postmortem study.
The Journal of neuropsychiatry and clinical neurosciences 1992;4(1):36-41.
1991: Marc Laruelle; A Sidhu; M F Casanova; Daniel R Weinberger; Joel E Kleinman
Characterization of [125I]SCH 23982 binding in human brain: comparison with [3H]SCH 23390.
Neuroscience letters 1991;131(2):273-6.
1991: H T Chen; M F Casanova; Joel E Kleinman; M Zito; David Goldman; Markku Linnoila
3H-paroxetine binding in brains of alcoholics.
Psychiatry research 1991;38(3):293-9.
1991: Barbara K Lipska; george jaskiw; F Karoum; I Phillips; Joel E Kleinman; Daniel R Weinberger
Dorsal hippocampal lesion does not affect dopaminergic indices in the basal ganglia.
Pharmacology, biochemistry, and behavior 1991;40(1):181-4.
1991: D G Daniel; Daniel R Weinberger; Douglas W Jones; J R Zigun; Richard Coppola; S Handel; L B Bigelow; Terry Goldberg; Karen Faith Berman; Joel E Kleinman
The effect of amphetamine on regional cerebral blood flow during cognitive activation in schizophrenia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(7):1907-17.
1991: D G Daniel; E Kim; D Kostianovsky; Terry Goldberg; M F Casanova; DAVID PICKAR; Joel E Kleinman; Daniel R Weinberger
Computed tomography measurements of brain density in Schizophrenia.
Biological psychiatry 1991;29(8):745-56.
1991: M F Casanova; Sakkubai Naidu; Terry Goldberg; H W Moser; S Khoromi; Anil Kumar; Joel E Kleinman; Daniel R Weinberger
Quantitative magnetic resonance imaging in Rett syndrome.
The Journal of neuropsychiatry and clinical neurosciences 1991;3(1):66-72.
1991: Daniel R Weinberger; R L Suddath; M F Casanova; E F Torrey; Joel E Kleinman
Crow's 'lateralization hypothesis' for schizophrenia.
Archives of general psychiatry 1991;48(1):85-7.
1991: Terry Goldberg; L B Bigelow; Daniel R Weinberger; D G Daniel; Joel E Kleinman
Cognitive and behavioral effects of the coadministration of dextroamphetamine and haloperidol in schizophrenia.
The American journal of psychiatry 1991;148(1):78-84.
1991: Thomas M Hyde; J R Hotson; Joel E Kleinman
Differential diagnosis of choreiform tardive dyskinesia.
The Journal of neuropsychiatry and clinical neurosciences 1991;3(3):255-68.
1990: george jaskiw; F Karoum; W J Freed; I Phillips; Joel E Kleinman; Daniel R Weinberger
Effect of ibotenic acid lesions of the medial prefrontal cortex on amphetamine-induced locomotion and regional brain catecholamine concentrations in the rat.
Brain research 1990;534(1-2):263-72.
1990: L L Altshuler; M F Casanova; Terry Goldberg; Joel E Kleinman
The hippocampus and parahippocampus in schizophrenia, suicide, and control brains.
Archives of general psychiatry 1990;47(11):1029-34.
1990: M F Casanova; Joel E Kleinman
The neuropathology of schizophrenia: a critical assessment of research methodologies.
Biological psychiatry 1990;27(3):353-62.
1990: M F Casanova; I N Waldman; Joel E Kleinman
A postmortem quantitative study of iron in the globus pallidus of schizophrenic patients.
Biological psychiatry 1990;27(2):143-9.
1990: M F Casanova; Terry Goldberg; R L Suddath; D G Daniel; R Rawlings; D G Lloyd; H L Loats; Joel E Kleinman; Daniel R Weinberger
Quantitative shape analysis of the temporal and prefrontal lobes of schizophrenic patients: a magnetic resonance image study.
The Journal of neuropsychiatry and clinical neurosciences 1990;2(4):363-72.
1990: M F Casanova; N Carosella; Joel E Kleinman
Neuropathological findings in a suspected case of childhood schizophrenia.
The Journal of neuropsychiatry and clinical neurosciences 1990;2(3):313-9.
1989: G W Christison; M F Casanova; Daniel R Weinberger; R Rawlings; Joel E Kleinman
A quantitative investigation of hippocampal pyramidal cell size, shape, and variability of orientation in schizophrenia.
Archives of general psychiatry 1989;46(11):1027-32.
1989: M F Casanova; M Zito; L B Bigelow; B Berthot; R D Sanders; Joel E Kleinman
Axonal counts of the corpus callosum of schizophrenic patients.
The Journal of neuropsychiatry and clinical neurosciences 1989;1(4):391-3.
1988: Terry Goldberg; Joel E Kleinman; D G Daniel; M S Myslobodsky; J Daniel Ragland; Daniel R Weinberger
Dementia praecox revisited. Age disorientation, mental status, and ventricular enlargement.
The British journal of psychiatry : the journal of mental science 1988;153():187-90.
1988: Joel E Kleinman; M F Casanova; george jaskiw
The neuropathology of schizophrenia.
Schizophrenia bulletin 1988;14(2):209-16.