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John Klement

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Francois-Xavier Sicot; Takeshi Tsuda; Dessislava Markova; John F Klement; Machiko Arita; Rui-Zhu Zhang; Te-Cheng Pan; Robert P Mecham; David E Birk; Mon-Li Chu
Fibulin-2 is dispensable for mouse development and elastic fiber formation.
Qiaoli Li; Qiujie Jiang; Jennifer Larusso; John F Klement; Alan C Sartorelli; Martin G Belinsky; Gary Kruh; Jouni Uitto
Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.
John F Klement; Yasushi Matsuzaki; Qiu-Jie Jiang; Joseph Terlizzi; Hae Young Choi; Norihiro Fujimoto; Kehua Li; Leena Pulkkinen; David E Birk; John P Sundberg; Jouni Uitto
Targeted ablation of the abcc6 gene results in ectopic mineralization of connective tissues.

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2008: Francois-Xavier Sicot; Takeshi Tsuda; Dessislava Markova; John F Klement; Machiko Arita; Rui-Zhu Zhang; Te-Cheng Pan; Robert P Mecham; David E Birk; Mon-Li Chu
Fibulin-2 is dispensable for mouse development and elastic fiber formation.
Molecular and cellular biology 2008;28(3):1061-7.
2007: Qiaoli Li; Qiujie Jiang; Jennifer Larusso; John F Klement; Alan C Sartorelli; Martin G Belinsky; Gary Kruh; Jouni Uitto
Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.
Experimental dermatology 2007;16(10):853-9.
2005: John F Klement; Yasushi Matsuzaki; Qiu-Jie Jiang; Joseph Terlizzi; Hae Young Choi; Norihiro Fujimoto; Kehua Li; Leena Pulkkinen; David E Birk; John P Sundberg; Jouni Uitto
Targeted ablation of the abcc6 gene results in ectopic mineralization of connective tissues.
Molecular and cellular biology 2005;25(18):8299-310.
2004: Sirpa Aho; Kehua Li; Young Ryoo; Clair McGee; Akemi Ishida-Yamamoto; Jouni Uitto; John F Klement
Periplakin gene targeting reveals a constituent of the cornified cell envelope dispensable for normal mouse development.
Molecular and cellular biology 2004;24(14):6410-8.
2003: Michael Naso; Jouni Uitto; John F Klement
Transcriptional control of the mouse Col7a1 gene in keratinocytes: basal and transforming growth factor-beta regulated expression.
The Journal of investigative dermatology 2003;121(6):1469-78.
2003: Morgana Colombo; Raymond Brittingham; John F Klement; Ireneusz Majsterek; David E Birk; Jouni Uitto; Andrzej Fertala
Procollagen VII self-assembly depends on site-specific interactions and is promoted by cleavage of the NC2 domain with procollagen C-proteinase.
Biochemistry 2003;42(39):11434-42.
2003: Xianmin Meng; John F Klement; Dominic A Leperi; David E Birk; Takako Sasaki; Rupert Timpl; Jouni Uitto; Leena Pulkkinen
Targeted inactivation of murine laminin gamma2-chain gene recapitulates human junctional epidermolysis bullosa.
The Journal of investigative dermatology 2003;121(4):720-31.
1999: S Heinonen; M Männikkö; John F Klement; Diana Whitaker-Menezes; George F Murphy; Jouni Uitto
Targeted inactivation of the type VII collagen gene (Col7a1) in mice results in severe blistering phenotype: a model for recessive dystrophic epidermolysis bullosa.
Journal of cell science 1999;112 ( Pt 21)():3641-8.
1999: DJ Kouba; K Y Chung; T Nishiyama; L Vindevoghel; A Kon; John F Klement; Jouni Uitto; Alain Mauviel
Nuclear factor-kappa B mediates TNF-alpha inhibitory effect on alpha 2(I) collagen (COL1A2) gene transcription in human dermal fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):4226-34.