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Claus-Detlev Klemke

Research Profile

Disorders

Procedures

Anatomy

Chemicals & Drugs

Concepts & Ideas

Geographic Areas

Germany

Physiology

Gene Expression Regulation, Neoplastic

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Publications

TOP 3
Chalid Assaf; Jürgen C Becker; Marc Beyer; Antonio Cozzio; Edgar Dippel; Claus-Detlev Klemke; Peter Kurschat; Michael Weichenthal; Rudolf Stadler
Therapie der fortgeschrittenen kutanen T-Zell-Lymphome mit nichtpegyliertem liposomalem Doxorubicin - Konsensus der Lymphomgruppe der Arbeitsgemeinschaft Dermatologische Onkologie.
Chalid Assaf; Jürgen C Becker; Marc Beyer; Antonio Cozzio; Edgar Dippel; Claus-Detlev Klemke; Peter Kurschat; Michael Weichenthal; Rudolf Stadler
Treatment of advanced cutaneous T-cell lymphomas with non-pegylated liposomal doxorubicin - Consensus of the lymphoma group of the Working Group Dermatologic Oncology.
Nina Booken; Sergij Goerdt; Markus Heck; Wiebke K Peitsch; Claus-Detlev Klemke
Ulcerated nodules on the oral mucosa and fingers: lymphomatoid papulosis, type A.

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2013: Chalid Assaf; Jürgen C Becker; Marc Beyer; Antonio Cozzio; Edgar Dippel; Claus-Detlev Klemke; Peter Kurschat; Michael Weichenthal; Rudolf Stadler
Therapie der fortgeschrittenen kutanen T-Zell-Lymphome mit nichtpegyliertem liposomalem Doxorubicin - Konsensus der Lymphomgruppe der Arbeitsgemeinschaft Dermatologische Onkologie.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2013;11(4):338-47.
2013: Chalid Assaf; Jürgen C Becker; Marc Beyer; Antonio Cozzio; Edgar Dippel; Claus-Detlev Klemke; Peter Kurschat; Michael Weichenthal; Rudolf Stadler
Treatment of advanced cutaneous T-cell lymphomas with non-pegylated liposomal doxorubicin - Consensus of the lymphoma group of the Working Group Dermatologic Oncology.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2013;11(4):338-47.
2013: Nina Booken; Sergij Goerdt; Markus Heck; Wiebke K Peitsch; Claus-Detlev Klemke
Ulcerated nodules on the oral mucosa and fingers: lymphomatoid papulosis, type A.
Acta dermato-venereologica 2013;93(2):250-1.
2013: Nina Booken; Jan Peter Nicolay; Christel Weiss; Claus-Detlev Klemke
Cutaneous tumor cell load correlates with survival in patients with Sézary syndrome.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2013;11(1):67-79.
2012: Markus Brechmann; Rebecca Breuer; Felice Frey; Marco Herling; Michael Kiessling; Claus-Detlev Klemke; Peter H Krammer; Thomas Mock; Wolfgang Müller; Dorothee Nickles; Jan P Nicolay; Yvonne Samstag; Guido H Wabnitz; Nicole Weit; Nina Booken; Michael Boutros; Rüdiger Arnold
A PP4 holoenzyme balances physiological and oncogenic nuclear factor-kappa B signaling in T lymphocytes.
Immunity 2012;37(4):697-708.
2012: M Felcht; S Goerdt; M Heck; C S L Müller; D Nashan; J P Nicolay; M M Sachse; C Weiss; J C Becker; N Booken; E Dippel; Claus-Detlev Klemke
Expression of the T-cell regulatory marker FOXP3 in primary cutaneous large B-cell lymphoma tumour cells.
The British journal of dermatology 2012;167(2):348-58.
2012: Nina Booken; Sergij Goerdt; Claus-Detlev Klemke
Clinical spectrum of primary cutaneous CD30-positive anaplastic large cell lymphoma: an analysis of the Mannheim Cutaneous Lymphoma Registry.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2012;10(5):331-9.
2011: Claus-Detlev Klemke
[Systemic treatment of cutaneous lymphomas].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2011;62(6):436-43.
2011: N Booken; M Heck; J P Nicolay; Claus-Detlev Klemke; Sergij Goerdt; Jochen Utikal
Oral aprepitant in the therapy of refractory pruritus in erythrodermic cutaneous T-cell lymphoma.
The British journal of dermatology 2011;164(3):665-7.
2011: Michael K Kiessling; Patrick A Oberholzer; Chandrani Mondal; Maria B Karpova; Marie C Zipser; William M Lin; Michael Girardi; Laura E Macconaill; Sarah M Kehoe; Charlie Hatton; Lars E French; Levi A Garraway; Gernot Polier; Dorothee Süss; Claus-Detlev Klemke; Peter H Krammer; Karsten Gülow; Reinhard Dummer
High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade.
Blood 2011;117(8):2433-40.
2011: C Géraud; Sergij Goerdt; Claus-Detlev Klemke
Primary cutaneous CD8+ small/medium-sized pleomorphic T-cell lymphoma, ear-type: a unique cutaneous T-cell lymphoma with a favourable prognosis.
The British journal of dermatology 2011;164(2):456-8.
2011: Moritz Felcht; Nina Booken; Philipp Stroebel; Sergij Goerdt; Claus-Detlev Klemke
The value of molecular diagnostics in primary cutaneous B-cell lymphomas in the context of clinical findings, histology, and immunohistochemistry.
Journal of the American Academy of Dermatology 2011;64(1):135-43, 143.e1-4.
2010: Melanie Kremer; Katja Sliva; Claus-Detlev Klemke; Barbara S Schnierle
Cutaneous T-cell lymphoma cells are sensitive to rapamycin.
Experimental dermatology 2010;19(9):800-5.
2010: M Linke; C Géraud; Wiebke K Peitsch; Sergij Goerdt; Claus-Detlev Klemke; Jochen Utikal
[Exulcerated, nodular tumor on the occiput of a 29-year-old patient].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2010;61(8):700-4.
2010: Nina Booken; Christel Weiss; Jochen Utikal; Moritz Felcht; Sergij Goerdt; Claus-Detlev Klemke
Combination therapy with extracorporeal photopheresis, interferon-alpha, PUVA and topical corticosteroids in the management of Sézary syndrome.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2010;8(6):428-38.
2010: Jörg Faulhaber; M Felcht; G Teerling; Claus-Detlev Klemke; C Wagner; Sergij Goerdt; Wolfgang Koenen
Long-term results after reconstruction of full thickness scalp defects with a dermal regeneration template.
Journal of the European Academy of Dermatology and Venereology : JEADV 2010;24(5):572-7.
2010: Moritz Felcht; Matthias Goebeler; Sergij Goerdt; Thomas Henzler; Alexander Marx; Kirsten Merx; Ute Moog; Philipp Stroebel; Urs Voßmerbäumer; Nina Booken; Nicola Dikow; Claus-Detlev Klemke
Warty skin changes, chronic scrotal lymphoedema, and facial dysmorphism.
BMJ case reports 2010;2010():.
2009: Julia B Heid; Angelika Schmidt; Nina Oberle; Sergij Goerdt; Peter H Krammer; Elisabeth Suri-Payer; Claus-Detlev Klemke
FOXP3+CD25- tumor cells with regulatory function in Sézary syndrome.
The Journal of investigative dermatology 2009;129(12):2875-85.
2009: N Booken; S Goerdt; Claus-Detlev Klemke
Probiotic supplementation: an alternative in the treatment of mycosis fungoides?
Journal of the European Academy of Dermatology and Venereology : JEADV 2009;23(12):1459-61.
2009: Jörg Faulhaber; Claus-Detlev Klemke; Sergij Goerdt; Wolfgang Koenen
[Nasal reconstruction using a titanium mesh].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2009;7(11):991-2.
2009: Moritz Felcht; Wiebke K Peitsch; Sergij Goerdt; Claus-Detlev Klemke
[Growing nodi on hand and knee of a 33-years old patient from Brazil].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2009;7(6):557-9.
2009: Andreas Lange; Claudia Kistler; Tanja B Jutzi; Alexandr V Bazhin; Claus-Detlev Klemke; Dirk Schadendorf; Stefan B Eichmüller
Detergent fractionation with subsequent subtractive suppression hybridization as a tool for identifying genes coding for plasma membrane proteins.
Experimental dermatology 2009;18(6):527-35.
2009: Claus-Detlev Klemke; Dirk Brenner; Eva-Maria Weiss; Marc Schmidt; Martin Leverkus; Karsten Gülow; Peter H Krammer
Lack of T-cell receptor-induced signaling is crucial for CD95 ligand up-regulation and protects cutaneous T-cell lymphoma cells from activation-induced cell death.
Cancer research 2009;69(10):4175-83.
2009: Michael K Kiessling; Claus-Detlev Klemke; Marcin Kaminski; Ioanna Galani; Peter H Krammer; Karsten Gülow
Inhibition of constitutively activated nuclear factor-kappaB induces reactive oxygen species- and iron-dependent cell death in cutaneous T-cell lymphoma.
Cancer research 2009;69(6):2365-74.
2008: Claus-Detlev Klemke; Sergij Goerdt
Molecular biology and targeted therapy of cutaneous T-cell lymphomas.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia 2008;143(6):365-74.
2008: Claus-Detlev Klemke; J Brade; S Weckesser; M M Sachse; N Booken; Michael Neumaier; Sergij Goerdt; T C Nebe
The diagnosis of Sézary syndrome on peripheral blood by flow cytometry requires the use of multiple markers.
The British journal of dermatology 2008;159(4):871-80.
2008: Rudolf Stadler; Chalid Assaf; Claus-Detlev Klemke; Dorothee Nashan; Michael Weichenthal; Reinhard Dummer; Wolfram Sterry
Short German guidelines: cutaneous lymphomas.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2008;6 Suppl 1():S25-31.
2008: Nina Booken; Jochen Utikal; Ralf Hildenbrand; Sergij Goerdt; Claus-Detlev Klemke
[Annular erythema in a 78-year old woman].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2008;6(4):321-3.
2008: N Booken; Alexei Gratchev; Jochen Utikal; C Weiss; X Yu; M Qadoumi; M Schmuth; N Sepp; Dorothée Nashan; K Rass; T Tüting; Chalid Assaf; Edgar Dippel; Rudolf Stadler; Claus-Detlev Klemke; Sergij Goerdt
Sézary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3.
Leukemia 2008;22(2):393-9.
2007: Chalid Assaf; Sylke Gellrich; Matthias Steinhoff; Dorothée Nashan; Franca Weisse; Edgar Dippel; Esther Coors; Anette Stein; Philippa Gollin; Ulrike Henke; Sabrina Adam-Murati; André Koch; Claus-Detlev Klemke; Rudolf Stadler; Wolfram Sterry
Cutaneous lymphomas in Germany: an analysis of the Central Cutaneous Lymphoma Registry of the German Society of Dermatology (DDG).
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2007;5(8):662-8.
2007: B Franz; Benedikt Fritzsching; A Riehl; Nina Oberle; Claus-Detlev Klemke; Jaromir Sykora; S Quick; Christine Stumpf; Marius Hartmann; A Enk; T Ruzicka; Peter H Krammer; Elisabeth Suri-Payer; A Kuhn
Low number of regulatory T cells in skin lesions of patients with cutaneous lupus erythematosus.
Arthritis and rheumatism 2007;56(6):1910-20.
2007: Mieun Lee; Claudia Kistler; Tanja B Hartmann; Fang Li; Reinhard Dummer; Edgar Dippel; Nina Booken; Claus-Detlev Klemke; Dirk Schadendorf; Stefan B Eichmüller
Immunoscreening of a cutaneous T-cell lymphoma library for plasma membrane proteins.
Cancer immunology, immunotherapy : CII 2007;56(6):783-95.
2007: Wiebke K Peitsch; Claus-Detlev Klemke; M S Michel; Sergij Goerdt; Christiane Bayerl
[Hematogenous contact dermatitis after intravesicular instillation of mitomycin C].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2007;58(3):246-9.
2007: Claus-Detlev Klemke; Bjsrn Held; Edgar Dippel; Sergij Goerdt
Multiple juvenile xanthogranulomas successfully treated with CO laser.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2007;5(1):30-3.
2006: Hjalmar Kurzen; Carmen Henrich; Dirk Booken; Nina Poenitz; Alexei Gratchev; Claus-Detlev Klemke; Monika Engstner; Sergij Goerdt; Nicole Maas-Szabowski
Functional characterization of the epidermal cholinergic system in vitro.
The Journal of investigative dermatology 2006;126(11):2458-72.
2006: Claus-Detlev Klemke; Benedikt Fritzsching; B Franz; E V Kleinmann; Nina Oberle; Nina Poenitz; Jaromir Sykora; Alison H Banham; Giovanna Roncador; A Kuhn; Sergij Goerdt; Peter H Krammer; Elisabeth Suri-Payer
Paucity of FOXP3+ cells in skin and peripheral blood distinguishes Sézary syndrome from other cutaneous T-cell lymphomas.
Leukemia 2006;20(6):1123-9.
2006: Jochen Utikal; Nina Poenitz; Alexei Gratchev; Claus-Detlev Klemke; Dorothea Nashan; Thomas Tüting; Sergij Goerdt
Additional Her 2/neu gene copies in patients with Sézary syndrome.
Leukemia research 2006;30(6):755-60.
2006: Claus-Detlev Klemke; Sergij Goerdt; David Schrama; Jürgen C Becker
New insights into the molecular biology and targeted therapy of cutaneous T-cell lymphomas.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2006;4(5):395-406.
2006: Claus-Detlev Klemke; Nina Poenitz; Edgar Dippel; Michael Hummel; Harald Stein; Sergij Goerdt
T-cell clonality of undetermined significance.
Archives of dermatology 2006;142(3):393-4.
2005: Claus-Detlev Klemke; U Mansmann; Nina Poenitz; Edgar Dippel; Sergij Goerdt
Prognostic factors and prediction of prognosis by the CTCL Severity Index in mycosis fungoides and Sézary syndrome.
The British journal of dermatology 2005;153(1):118-24.
2005: Nina Poenitz; Dorothea Tadler; Claus-Detlev Klemke; Elke Glorer; Sergij Goerdt
[Ulceration of the scalp: a unique manifestation of pyoderma gangrenosum].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2005;3(2):113-6.
2005: Nina Poenitz; J Simon-Ackermann; Alexei Gratchev; M Qadoumi; Claus-Detlev Klemke; Rudolf Stadler; Almut Kremer; M Radenhausen; U Henke; Chalid Assaf; Jochen Utikal; Sergij Goerdt; Edgar Dippel
Overexpression of c-myb in leukaemic and non-leukaemic variants of cutaneous T-cell lymphoma.
Dermatology (Basel, Switzerland) 2005;211(2):84-92.
2004: Tanja Hördt; Claus-Detlev Klemke; Edgar Dippel; Sergij Goerdt
[Ulcerated red, livid nodule on the scrotum of a 64-year old man].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2004;2(12):1027-9.
2003: Edgar Dippel; Sylke Gellrich; Claus-Detlev Klemke; Sergij Goerdt; Wolfram Sterry
[Cutaneous T-cell lymphoma].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2003;1(12):965-80; quiz 981-2.
2003: Claus-Detlev Klemke; Edgar Dippel; Christoph C Geilen; Michael P Koenigsmann; Eckhard Thiel; Constantin E Orfanos; Sergij Goerdt
Atypical generalized eruptive histiocytosis associated with acute monocytic leukemia.
Journal of the American Academy of Dermatology 2003;49(5 Suppl):S233-6.
2003: Edgar Dippel; Claus-Detlev Klemke; Sergij Goerdt
Current status of cutaneous T-cell lymphoma: molecular diagnosis, pathogenesis, therapy and future directions.
Onkologie 2003;26(5):477-83.
2003: Jochen Utikal; Claus-Detlev Klemke; Alexei Gratchev; Sergij Goerdt
[Cutaneous non-Langerhans' cell histiocytoses].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2003;1(6):471-91; quiz 492-3.
2003: Edgar Dippel; Jochen Utikal; G Feller; N Fackel; Claus-Detlev Klemke; R Happle; Sergij Goerdt
Nevi flammei affecting two contralateral quadrants and nevus depigmentosus: a new type of phacomatosis pigmentovascularis?
American journal of medical genetics. Part A 2003;119A(2):228-30.
2003: Chalid Assaf; Michael Hummel; Edgar Dippel; Stefan Schwartz; Christoph C Geilen; Lana Harder; Reiner Siebert; Matthias Steinhoff; Claus-Detlev Klemke; Eckhard Thiel; Sergij Goerdt; Harald Stein; Constantin E Orfanos
Common clonal T-cell origin in a patient with T-prolymphocytic leukaemia and associated cutaneous T-cell lymphomas.
British journal of haematology 2003;120(3):488-91.
2003: Claus-Detlev Klemke; D Siebold; Edgar Dippel; Ralf Hildenbrand; Uwe Bleyl; Sergij Goerdt
Generalised annular elastolytic giant cell granuloma.
Dermatology (Basel, Switzerland) 2003;207(4):420-2.
2003: Jochen Utikal; Darinka Keil; Claus-Detlev Klemke; Christiane Bayerl; Sergij Goerdt
Predominant telangiectatic erythema in linear atrophoderma of Moulin: novel variant or separate entity?
Dermatology (Basel, Switzerland) 2003;207(3):310-5.
2003: Nina Poenitz; Edgar Dippel; Claus-Detlev Klemke; M Qadoumi; Sergij Goerdt
Jessner's lymphocytic infiltration of the skin: a CD8+ polyclonal reactive skin condition.
Dermatology (Basel, Switzerland) 2003;207(3):276-84.
2003: Jochen Utikal; E Beck; E Dippel; Claus-Detlev Klemke; S Goerdt
Reiter's syndrome-like pattern in AIDS-associated psoriasiform dermatitis.
Journal of the European Academy of Dermatology and Venereology : JEADV 2003;17(1):114-6.
2002: Claus-Detlev Klemke; Edgar Dippel; Antje Dembinski; Nina Pönitz; Chalid Assaf; Michael Hummel; Harald Stein; Sergij Goerdt
Clonal T cell receptor gamma-chain gene rearrangement by PCR-based GeneScan analysis in the skin and blood of patients with parapsoriasis and early-stage mycosis fungoides.
The Journal of pathology 2002;197(3):348-54.
2002: Claus-Detlev Klemke; Sergij Goerdt; Constantin E Orfanos; Ulrike Blume-Peytavi
[Persistent hemorrhagic crusts on the lips of a 13-year-old patient. Cheilitis crustosa factitia].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2002;53(4):265-7.
2002: Edgar Dippel; Nina Poenitz; Claus-Detlev Klemke; Constantin E Orfanos; Sergij Goerdt
Familial lymphocytic infiltration of the skin: histochemical and molecular analysis in three brothers.
Dermatology (Basel, Switzerland) 2002;204(1):12-6.
2000: Claus-Detlev Klemke; S Nestoris; LU Wölfer; S Krengel; Christos Zouboulis; Beate Tebbe; Sergij Goerdt
[Radiation-induced acne].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2000;51(3):187-91.
1999: Claus-Detlev Klemke; Edgar Dippel; Chalid Assaf; Michael Hummel; Harald Stein; Sergij Goerdt; Constantin E Orfanos
Follicular mycosis fungoides.
The British journal of dermatology 1999;141(1):137-40.
1999: Sergij Goerdt; Oliver Politz; Kai Schledzewski; RW Birk; Alexei Gratchev; P Guillot; N Hakiy; Claus-Detlev Klemke; Edgar Dippel; V Kodelja; Constantin E Orfanos
Alternative versus classical activation of macrophages.
Pathobiology : journal of immunopathology, molecular and cellular biology 1999;67(5-6):222-6.