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Vadim Klenchin

Research Profile

Chemicals & Drugs

Procedures

X Ray Crystallography

Physiology

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Rats

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PC12 Cells

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Amino Acid Sequences

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Publications

TOP 3
Jeremiah Frye; Vadim A Klenchin; Ivan Rayment
Structure of the tropomyosin overlap complex from chicken smooth muscle: insight into the diversity of N-terminal recognition.
Jeremiah J Frye; Vadim A Klenchin; Clive R Bagshaw; Ivan Rayment
Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236.
Mari Nojiri; Kelly M Loyet; Vadim A Klenchin; Gregory Kabachinski; Thomas F J Martin
CAPS activity in priming vesicle exocytosis requires CK2 phosphorylation.

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All Publications

2010: Jeremiah Frye; Vadim A Klenchin; Ivan Rayment
Structure of the tropomyosin overlap complex from chicken smooth muscle: insight into the diversity of N-terminal recognition.
Biochemistry 2010;49(23):4908-20.
2010: Jeremiah J Frye; Vadim A Klenchin; Clive R Bagshaw; Ivan Rayment
Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236.
Biochemistry 2010;49(23):4897-907.
2009: Mari Nojiri; Kelly M Loyet; Vadim A Klenchin; Gregory Kabachinski; Thomas F J Martin
CAPS activity in priming vesicle exocytosis requires CK2 phosphorylation.
The Journal of biological chemistry 2009;284(28):18707-14.
2008: Vadim A Klenchin; Agata Czyz; Igor Y Goryshin; Richard Gradman; Scott Lovell; Ivan Rayment; William S Reznikoff
Phosphate coordination and movement of DNA in the Tn5 synaptic complex: role of the (R)YREK motif.
Nucleic acids research 2008;36(18):5855-62.
2008: C J Rocco; K L Dennison; Vadim A Klenchin; Ivan Rayment; Jorge C Escalante-Semerena
Construction and use of new cloning vectors for the rapid isolation of recombinant proteins from Escherichia coli.
Plasmid 2008;59(3):231-7.
2006: Vadim A Klenchin; Sofia Yu Khaitlina; Ivan Rayment
Crystal structure of polymerization-competent actin.
Journal of molecular biology 2006;362(1):140-50.
2006: John S Allingham; Vadim A Klenchin; Ivan Rayment
Actin-targeting natural products: structures, properties and mechanisms of action.
Cellular and molecular life sciences : CMLS 2006;63(18):2119-34.
2005: Vadim A Klenchin; Ryan King; Junichi Tanaka; Gerard Marriott; Ivan Rayment
Structural basis of swinholide A binding to actin.
Chemistry & biology 2005;12(3):287-91.
2004: Ruslan Grishanin; Judith A Kowalchyk; Vadim A Klenchin; Kyoungsook Ann; Cynthia A Earles; Edwin R Chapman; Roy R L Gerona; Thomas F J Martin
CAPS acts at a prefusion step in dense-core vesicle exocytosis as a PIP2 binding protein.
Neuron 2004;43(4):551-62.
2004: Vadim A Klenchin; Dawn M Z Schmidt; John Alan Gerlt; Ivan Rayment
Evolution of enzymatic activities in the enolase superfamily: structure of a substrate-liganded complex of the L-Ala-D/L-Glu epimerase from Bacillus subtilis.
Biochemistry 2004;43(32):10370-8.
2003: Vadim A Klenchin; Erika Taylor; John Alan Gerlt; Ivan Rayment
Evolution of enzymatic activity in the enolase superfamily: structural and mutagenic studies of the mechanism of the reaction catalyzed by o-succinylbenzoate synthase from Escherichia coli.
Biochemistry 2003;42(49):14427-33.
2003: Vadim A Klenchin; John S Allingham; Ryan King; Junichi Tanaka; Gerard Marriott; Ivan Rayment
Trisoxazole macrolide toxins mimic the binding of actin-capping proteins to actin.
Nature structural biology 2003;10(12):1058-63.
2003: Junichi Tanaka; Yuling Yan; Jeongeun Choi; Jihong Bai; Vadim A Klenchin; Ivan Rayment; Gerard Marriott
Biomolecular mimicry in the actin cytoskeleton: mechanisms underlying the cytotoxicity of kabiramide C and related macrolides.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):13851-6.
2002: Ruslan Grishanin; Vadim A Klenchin; Kelly M Loyet; Judith A Kowalchyk; Kyoungsook Ann; Thomas F J Martin
Membrane association domains in Ca2+-dependent activator protein for secretion mediate plasma membrane and dense-core vesicle binding required for Ca2+-dependent exocytosis.
The Journal of biological chemistry 2002;277(24):22025-34.
2001: Markus R Wenk; Lorenzo Pellegrini; Vadim A Klenchin; Gilbert Di Paolo; Sunghoe Chang; Laurie Daniell; M Arioka; Thomas F J Martin; Pietro De Camilli
PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapse.
Neuron 2001;32(1):79-88.
2000: Vadim A Klenchin; Thomas F J Martin
Priming in exocytosis: attaining fusion-competence after vesicle docking.
Biochimie 2000;82(5):399-407.
1999: Scott E Phillips; B Sha; L Topalof; Zhigang Xie; James G Alb; Vadim A Klenchin; Philip Swigart; Shamshad Cockcroft; Thomas F J Martin; M Luo; Vytas A Bankaitis
Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivo.
Molecular cell 1999;4(2):187-97.
1998: Vadim A Klenchin; Judith A Kowalchyk; Thomas F J Martin
Large dense-core vesicle exocytosis in PC12 cells.
Methods (San Diego, Calif.) 1998;16(2):204-8.