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Hans-Dieter Klenk

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Larissa Kolesnikova; Stephan Becker; Sonja Heck; Hans-Dieter Klenk; Tatyana Matrosovich; Mikhail Matrosovich
Influenza virus budding from the tips of cellular microvilli in differentiated human airway epithelial cells.
Sarah Katharina Fehling; Wolfgang Garten; Yoshihiro Kawaoka; Hans-Dieter Klenk; Boris Lamp; Andrea Maisner; Takeshi Noda; Karl-Klaus Conzelmann; Thomas Strecker
The microtubule motor protein KIF13A is involved in intracellular trafficking of the Lassa virus matrix protein Z.
Joanna Baron; Wolfgang Garten; Yi Guan; Maya Hammami; Hans-Dieter Klenk; Deborah Mayoli-Nüssle; Daniela Meyer; Eva Schilling; Folker Schwalm; Torsten Steinmetzer; Carolin Tarnow; Eva Böttcher-Friebertshäuser
Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.

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All Publications

2013: Larissa Kolesnikova; Stephan Becker; Sonja Heck; Hans-Dieter Klenk; Tatyana Matrosovich; Mikhail Matrosovich
Influenza virus budding from the tips of cellular microvilli in differentiated human airway epithelial cells.
The Journal of general virology 2013;94(Pt 5):971-6.
2013: Sarah Katharina Fehling; Wolfgang Garten; Yoshihiro Kawaoka; Hans-Dieter Klenk; Boris Lamp; Andrea Maisner; Takeshi Noda; Karl-Klaus Conzelmann; Thomas Strecker
The microtubule motor protein KIF13A is involved in intracellular trafficking of the Lassa virus matrix protein Z.
Cellular microbiology 2013;15(2):315-34.
2013: Joanna Baron; Wolfgang Garten; Yi Guan; Maya Hammami; Hans-Dieter Klenk; Deborah Mayoli-Nüssle; Daniela Meyer; Eva Schilling; Folker Schwalm; Torsten Steinmetzer; Carolin Tarnow; Eva Böttcher-Friebertshäuser
Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.
Journal of virology 2013;87(3):1811-20.
2013: Hans-Dieter Klenk
[Evolution and infection biology of new influenza A viruses with pandemic potential].
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 2013;56(1):15-21.
2012: Eva Böttcher-Friebertshäuser; Hans-Dieter Klenk; Yinghui Lu; Daniela Meyer; Frank Sielaff; Torsten Steinmetzer; Wolfgang Garten
Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections.
Vaccine 2012;30(51):7374-80.
2012: T Gerlach; Hans-Dieter Klenk; L Kühling; V Laukemper; Tatyana Matrosovich; F Schwalm; J Uhlendorff; V Czudai-Matwich; Mikhail Matrosovich
Characterization of the neuraminidase of the H1N1/09 pandemic influenza virus.
Vaccine 2012;30(51):7348-52.
2012: Alexandra S Gambaryan; Hans-Dieter Klenk; Scott L Krauss; Jill Banks; Nicolai V Bovin; Ilaria Capua; Giovanni Cattoli; Ron A M Fouchier; Tatyana Matrosovich; Vincent J Munster; Jennifer Philipp; Robert G Webster; Mikhail Matrosovich
Receptor-binding profiles of H7 subtype influenza viruses in different host species.
Journal of virology 2012;86(8):4370-9.
2011: Jürgen Stech; Olga Stech; Thorsten Wolff; Thomas C Mettenleiter; Bianca Dauber; Holger Garn; Astrid Herwig; Hans-Dieter Klenk
Influenza B virus with modified hemagglutinin cleavage site as a novel attenuated live vaccine.
The Journal of infectious diseases 2011;204(10):1483-90.
2011: Hans-Dieter Klenk
[Flu outbreaks. Influenza viruses on the way from animal to man].
Pharmazie in unserer Zeit 2011;40(2):104-8.
2011: Eva Böttcher-Friebertshäuser; David A Stein; Hans-Dieter Klenk; Wolfgang Garten
Inhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2.
Journal of virology 2011;85(4):1554-62.
2010: Bjoern Keiner; Benjamin Maenz; Ralf Wagner; Giovanni Cattoli; Ilaria Capua; Hans-Dieter Klenk
Intracellular distribution of NS1 correlates with the infectivity and interferon antagonism of an avian influenza virus (H7N1).
Journal of virology 2010;84(22):11858-65.
2010: Yan Liu; Robert A Childs; Tatyana Matrosovich; Stephen Wharton; Angelina S Palma; Wengang Chai; Rodney Daniels; Victoria Gregory; Jennifer Uhlendorff; Makoto Kiso; Hans-Dieter Klenk; Alan Hay; Ten Feizi; Mikhail Matrosovich
Altered receptor specificity and cell tropism of D222G hemagglutinin mutants isolated from fatal cases of pandemic A(H1N1) 2009 influenza virus.
Journal of virology 2010;84(22):12069-74.
2010: Eva Böttcher-Friebertshäuser; Catharina Freuer; Frank Sielaff; Sarah Schmidt; Markus Eickmann; Jennifer Uhlendorff; Torsten Steinmetzer; Hans-Dieter Klenk; Wolfgang Garten
Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors.
Journal of virology 2010;84(11):5605-14.
2009: Eva Böttcher; Catharina Freuer; Torsten Steinmetzer; Hans-Dieter Klenk; Wolfgang Garten
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.
Vaccine 2009;27(45):6324-9.
2009: Anna Maisa; Ute Ströher; Hans-Dieter Klenk; Wolfgang Garten; Thomas Strecker
Inhibition of Lassa virus glycoprotein cleavage and multicycle replication by site 1 protease-adapted alpha(1)-antitrypsin variants.
PLoS neglected tropical diseases 2009;3(6):e446.
2009: Jennifer Uhlendorff; Tatyana Matrosovich; Hans-Dieter Klenk; Mikhail Matrosovich
Functional significance of the hemadsorption activity of influenza virus neuraminidase and its alteration in pandemic viruses.
Archives of virology 2009;154(6):945-57.
2008: Jürgen Stech; Olga Stech; Astrid Herwig; Hermann Altmeppen; Jana Hundt; Sandra Gohrbandt; Anne Kreibich; Siegfried Weber; Hans-Dieter Klenk; Thomas C Mettenleiter
Rapid and reliable universal cloning of influenza A virus genes by target-primed plasmid amplification.
Nucleic acids research 2008;36(21):e139.
2008: Gülsah Gabriel; Alexandra Nordmann; David A Stein; Patrick L Iversen; Hans-Dieter Klenk
Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus.
The Journal of general virology 2008;89(Pt 4):939-48.
2008: Nicole Runkler; Erik Dietzel; Markus Moll; Hans-Dieter Klenk; Andrea Maisner
Glycoprotein targeting signals influence the distribution of measles virus envelope proteins and virus spread in lymphocytes.
The Journal of general virology 2008;89(Pt 3):687-96.
2008: G Gabriel; Holger Garn; Michael Wegmann; Harald Renz; Astrid Herwig; Hans-Dieter Klenk; Jürgen Stech
The potential of a protease activation mutant of a highly pathogenic avian influenza virus for a pandemic live vaccine.
Vaccine 2008;26(7):956-65.
2008: Gülsah Gabriel; Astrid Herwig; Hans-Dieter Klenk
Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus.
PLoS pathogens 2008;4(2):e11.
2007: Steven M Jones; Ute Stroher; Lisa Fernando; Xianggou Qiu; Judie B Alimonti; Pasquale L Melito; Mike Bray; Hans-Dieter Klenk; Heinz Feldmann
Assessment of a vesicular stomatitis virus-based vaccine by use of the mouse model of Ebola virus hemorrhagic fever.
The Journal of infectious diseases 2007;196 Suppl 2():S404-12.
2007: Werner Slenczka; Hans-Dieter Klenk
Forty years of marburg virus.
The Journal of infectious diseases 2007;196 Suppl 2():S131-5.
2007: G Gabriel; M Abram; B Keiner; Ralf Wagner; Hans-Dieter Klenk; Jürgen Stech
Differential polymerase activity in avian and mammalian cells determines host range of influenza virus.
Journal of virology 2007;81(17):9601-4.
2007: Mikhail Matrosovich; Tatyana Matrosovich; Jennifer Uhlendorff; Wolfgang Garten; Hans-Dieter Klenk
Avian-virus-like receptor specificity of the hemagglutinin impedes influenza virus replication in cultures of human airway epithelium.
Virology 2007;361(2):384-90.
2007: Nicole Runkler; Christine Pohl; Sibylle Schneider-Schaulies; Hans-Dieter Klenk; Andrea Maisner
Measles virus nucleocapsid transport to the plasma membrane requires stable expression and surface accumulation of the viral matrix protein.
Cellular microbiology 2007;9(5):1203-14.
2006: Eva Böttcher; Tatyana Matrosovich; Michaela Beyerle; Hans-Dieter Klenk; Wolfgang Garten; Mikhail Matrosovich
Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium.
Journal of virology 2006;80(19):9896-8.
2006: Henju Marjuki; Mohammad I Alam; Christina Ehrhardt; Ralf Wagner; Oliver Planz; Hans-Dieter Klenk; Stephan Ludwig; Stephan Pleschka
Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling.
The Journal of biological chemistry 2006;281(24):16707-15.
2006: Jürgen Stech; Hans-Dieter Klenk
A new approach to an influenza life vaccine: haemagglutinin cleavage site mutants generated by reverse genetics.
Berliner und Münchener tierärztliche Wochenschrift 2006;119(3-4):186-91.
2006: Mikhail Matrosovich; Takashi Suzuki; Yoshio Hirabayashi; Wolfgang Garten; Robert G Webster; Hans-Dieter Klenk
Gangliosides are not essential for influenza virus infection.
Glycoconjugate journal 2006;23(1-2):107-13.
2006: Mikhail Matrosovich; Tatyana Matrosovich; Wolfgang Garten; Hans-Dieter Klenk
New low-viscosity overlay medium for viral plaque assays.
Virology journal 2006;3():63.
2006: Sven Enterlein; Viktor Volchkov; Michael Weik; Larissa Kolesnikova; Valentina Volchkova; Hans-Dieter Klenk; Elke Mühlberger
Rescue of recombinant Marburg virus from cDNA is dependent on nucleocapsid protein VP30.
Journal of virology 2006;80(2):1038-43.
2005: G Gabriel; Bianca Dauber; Thorsten Wolff; Oliver Planz; Hans-Dieter Klenk; Jürgen Stech
The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(51):18590-5.
2005: Peggy Möller; Nonia Pariente; Hans-Dieter Klenk; Stephan Becker
Homo-oligomerization of Marburgvirus VP35 is essential for its function in replication and transcription.
Journal of virology 2005;79(23):14876-86.
2005: Alexandra Gambaryan; E Y Boravleva; Tatyana Matrosovich; Mikhail Matrosovich; Hans-Dieter Klenk; E V Moiseeva; Alexander B Tuzikov; Alexander A Chinarev; Galina Pazynina; Nicolai V Bovin
Polymer-bound 6' sialyl-N-acetyllactosamine protects mice infected by influenza virus.
Antiviral research 2005;68(3):116-23.
2005: Sandra Bamberg; Larissa Kolesnikova; Peggy Möller; Hans-Dieter Klenk; Stephan Becker
VP24 of Marburg virus influences formation of infectious particles.
Journal of virology 2005;79(21):13421-33.
2005: Sandra Diederich; Markus Moll; Hans-Dieter Klenk; Andrea Maisner
The nipah virus fusion protein is cleaved within the endosomal compartment.
The Journal of biological chemistry 2005;280(33):29899-903.
2005: Hans-Dieter Klenk
Infection of the endothelium by influenza viruses.
Thrombosis and haemostasis 2005;94(2):262-5.
2005: Stephane Daffis; Roland Kontermann; Jehanara Korimbocus; Hervé Zeller; Hans-Dieter Klenk; Jan ter Meulen
Antibody responses against wild-type yellow fever virus and the 17D vaccine strain: characterization with human monoclonal antibody fragments and neutralization escape variants.
Virology 2005;337(2):262-72.
2005: Steven M Jones; Heinz Feldmann; Ute Ströher; Joan B Geisbert; Lisa Fernando; Allen Grolla; Hans-Dieter Klenk; Nancy J Sullivan; Viktor Volchkov; Elizabeth A Fritz; Kathleen M Daddario; Lisa E Hensley; Peter B Jahrling; Thomas W Geisbert
Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses.
Nature medicine 2005;11(7):786-90.
2005: Ralf Wagner; Astrid Herwig; Nahid Azzouz; Hans-Dieter Klenk
Acylation-mediated membrane anchoring of avian influenza virus hemagglutinin is essential for fusion pore formation and virus infectivity.
Journal of virology 2005;79(10):6449-58.
2005: Viktor Volchkov; Valentina Volchkova; Olga Dolnik; Heinz Feldmann; Hans-Dieter Klenk
Polymorphism of filovirus glycoproteins.
Advances in virus research 2005;64():359-81.
2004: Mikhail Matrosovich; Tatyana Matrosovich; Thomas Gray; Noel A Roberts; Hans-Dieter Klenk
Neuraminidase is important for the initiation of influenza virus infection in human airway epithelium.
Journal of virology 2004;78(22):12665-7.
2004: Markus Moll; Sandra Diederich; Hans-Dieter Klenk; Markus Czub; Andrea Maisner
Ubiquitous activation of the Nipah virus fusion protein does not require a basic amino acid at the cleavage site.
Journal of virology 2004;78(18):9705-12.
2004: Olga Dolnik; Valentina Volchkova; Wolfgang Garten; Caroline Carbonnelle; Stephan Becker; Jörg Kahnt; Ute Ströher; Hans-Dieter Klenk; Viktor Volchkov
Ectodomain shedding of the glycoprotein GP of Ebola virus.
The EMBO journal 2004;23(10):2175-84.
2004: Michael Garbutt; Ryan Liebscher; Victoria Wahl-Jensen; Steven Jones; Peggy Möller; Ralf Wagner; Viktor Volchkov; Hans-Dieter Klenk; Heinz Feldmann; Ute Ströher
Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses.
Journal of virology 2004;78(10):5458-65.
2004: Markus Moll; Joanna Pfeuffer; Hans-Dieter Klenk; Stefan Niewiesk; Andrea Maisner
Polarized glycoprotein targeting affects the spread of measles virus in vitro and in vivo.
The Journal of general virology 2004;85(Pt 4):1019-27.
2004: Mikhail Matrosovich; Tatyana Matrosovich; Thomas Gray; Noel A Roberts; Hans-Dieter Klenk
Human and avian influenza viruses target different cell types in cultures of human airway epithelium.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4620-4.
2004: Robert Eichler; Oliver Lenz; Thomas Strecker; Markus Eickmann; Hans-Dieter Klenk; Wolfgang Garten
Lassa virus glycoprotein signal peptide displays a novel topology with an extended endoplasmic reticulum luminal region.
The Journal of biological chemistry 2004;279(13):12293-9.
2004: Robert Eichler; Thomas Strecker; Larissa Kolesnikova; Jan ter Meulen; Winfried Weissenhorn; Stephan Becker; Hans-Dieter Klenk; Wolfgang Garten; Oliver Lenz
Characterization of the Lassa virus matrix protein Z: electron microscopic study of virus-like particles and interaction with the nucleoprotein (NP).
Virus research 2004;100(2):249-55.
2003: Hans-Dieter Klenk
In memoriam Rudolf Rott (1926-2003).
Archives of virology 2003;148(12):2489-91.
2003: Robert Eichler; Oliver Lenz; Thomas Strecker; Markus Eickmann; Hans-Dieter Klenk; Wolfgang Garten
Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor.
EMBO reports 2003;4(11):1084-8.
2003: Bettina Hartlieb; Jens Modrof; Elke Mühlberger; Hans-Dieter Klenk; Stephan Becker
Oligomerization of Ebola virus VP30 is essential for viral transcription and can be inhibited by a synthetic peptide.
The Journal of biological chemistry 2003;278(43):41830-6.
2003: Joanna Timmins; Guy Schoehn; Christine Kohlhaas; Hans-Dieter Klenk; Rob W H Ruigrok; Winfried Weissenhorn
Oligomerization and polymerization of the filovirus matrix protein VP40.
Virology 2003;312(2):359-68.
2003: Mikhail Matrosovich; Tatyana Matrosovich; Jackie Carr; Noel A Roberts; Hans-Dieter Klenk
Overexpression of the alpha-2,6-sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitors.
Journal of virology 2003;77(15):8418-25.
2003: Christopher F Basler; Andrea Mikulasova; Luis Martinez-Sobrido; Jason Paragas; Elke Mühlberger; Mike Bray; Hans-Dieter Klenk; Peter Palese; Adolfo García-Sastre
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
Journal of virology 2003;77(14):7945-56.
2003: F Xavier Gomis-Rüth; Andréa Dessen; Joanna Timmins; Andreas Bracher; Larissa Kolesnikowa; Stephan Becker; Hans-Dieter Klenk; Winfried Weissenhorn
The matrix protein VP40 from Ebola virus octamerizes into pore-like structures with specific RNA binding properties.
Structure (London, England : 1993) 2003;11(4):423-33.
2003: Mikhail Matrosovich; Hans-Dieter Klenk
Natural and synthetic sialic acid-containing inhibitors of influenza virus receptor binding.
Reviews in medical virology 2003;13(2):85-97.
2002: Jens Modrof; Elke Mühlberger; Hans-Dieter Klenk; Stephan Becker
Phosphorylation of VP30 impairs ebola virus transcription.
The Journal of biological chemistry 2002;277(36):33099-104.
2002: Dominic Wichmann; Hermann-Josef Gröne; Michael Frese; Jovan Pavlovic; Bärbel Anheier; Otto Haller; Hans-Dieter Klenk; Heinz Feldmann
Hantaan virus infection causes an acute neurological disease that is fatal in adult laboratory mice.
Journal of virology 2002;76(17):8890-9.
2002: Michael Weik; Jens Modrof; Hans-Dieter Klenk; Stephan Becker; Elke Mühlberger
Ebola virus VP30-mediated transcription is regulated by RNA secondary structure formation.
Journal of virology 2002;76(17):8532-9.
2002: Markus Moll; Hans-Dieter Klenk; Andrea Maisner
Importance of the cytoplasmic tails of the measles virus glycoproteins for fusogenic activity and the generation of recombinant measles viruses.
Journal of virology 2002;76(14):7174-86.
2002: Ralf Wagner; Mikhail Matrosovich; Hans-Dieter Klenk
Functional balance between haemagglutinin and neuraminidase in influenza virus infections.
Reviews in medical virology 2002;12(3):159-66.
2002: Christian Sänger; Elke Mühlberger; Beate Lötfering; Hans-Dieter Klenk; Stephan Becker
The Marburg virus surface protein GP is phosphorylated at its ectodomain.
Virology 2002;295(1):20-9.
2002: Ralf Wagner; Dagmar Heuer; Thorsten Wolff; Astrid Herwig; Hans-Dieter Klenk
N-Glycans attached to the stem domain of haemagglutinin efficiently regulate influenza A virus replication.
The Journal of general virology 2002;83(Pt 3):601-9.
2002: Petra Riedl; Markus Moll; Hans-Dieter Klenk; Andrea Maisner
Measles virus matrix protein is not cotransported with the viral glycoproteins but requires virus infection for efficient surface targeting.
Virus research 2002;83(1-2):1-12.
2002: Larissa Kolesnikova; Harald Bugany; Hans-Dieter Klenk; Stephan Becker
VP40, the matrix protein of Marburg virus, is associated with membranes of the late endosomal compartment.
Journal of virology 2002;76(4):1825-38.
2002: Hans-Dieter Klenk; Ralf Wagner; Dagmar Heuer; Thorsten Wolff
Importance of hemagglutinin glycosylation for the biological functions of influenza virus.
Virus research 2002;82(1-2):73-5.
2001: Heinz Feldmann; Viktor Volchkov; Valentina Volchkova; Ute Ströher; Hans-Dieter Klenk
Biosynthesis and role of filoviral glycoproteins.
The Journal of general virology 2001;82(Pt 12):2839-48.
2001: Hans-Dieter Klenk; Heinz Feldmann
Symposium on Marburg and Ebola viruses.
Virus research 2001;80(1-2):117-23.
2001: Ute Ströher; E West; H Bugany; Hans-Dieter Klenk; Hans-Joachim Schnittler; Heinz Feldmann
Infection and activation of monocytes by Marburg and Ebola viruses.
Journal of virology 2001;75(22):11025-33.
2001: C Löber; B Anheier; S Lindow; Hans-Dieter Klenk; H Feldmann
The Hantaan virus glycoprotein precursor is cleaved at the conserved pentapeptide WAASA.
Virology 2001;289(2):224-9.
2001: Oliver Lenz; Jan ter Meulen; Hans-Dieter Klenk; N G Seidah; Wolfgang Garten
The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(22):12701-5.
2001: Markus Moll; Hans-Dieter Klenk; Georg Herrler; Andrea Maisner
A single amino acid change in the cytoplasmic domains of measles virus glycoproteins H and F alters targeting, endocytosis, and cell fusion in polarized Madin-Darby canine kidney cells.
The Journal of biological chemistry 2001;276(21):17887-94.
2001: Viktor Volchkov; Valentina Volchkova; E Muhlberger; Larissa Kolesnikova; Michael Weik; Olga Dolnik; Hans-Dieter Klenk
Recovery of infectious Ebola virus from complementary DNA: RNA editing of the GP gene and viral cytotoxicity.
Science (New York, N.Y.) 2001;291(5510):1965-9.
2001: Christian Sänger; Elke Mühlberger; Elena Ryabchikova; Larissa Kolesnikova; Hans-Dieter Klenk; Stephan Becker
Sorting of Marburg virus surface protein and virus release take place at opposite surfaces of infected polarized epithelial cells.
Journal of virology 2001;75(3):1274-83.
2001: Christian Sänger; Elke Mühlberger; Hans-Dieter Klenk; Stephan Becker
Adverse effects of MVA-T7 on the transport of Marburg virus glycoprotein.
Journal of virological methods 2001;91(1):29-35.
2000: Sandra Scianimanico; Guy Schoehn; Joanna Timmins; R H Ruigrok; Hans-Dieter Klenk; Winfried Weissenhorn
Membrane association induces a conformational change in the Ebola virus matrix protein.
The EMBO journal 2000;19(24):6732-41.
2000: Oliver Lenz; Jan ter Meulen; H Feldmann; Hans-Dieter Klenk; Wolfgang Garten
Identification of a novel consensus sequence at the cleavage site of the Lassa virus glycoprotein.
Journal of virology 2000;74(23):11418-21.
2000: Viktor Volchkov; Alexander Chepurnov; Valentina Volchkova; V A Ternovoj; Hans-Dieter Klenk
Molecular characterization of guinea pig-adapted variants of Ebola virus.
Virology 2000;277(1):147-55.
2000: Christopher F Basler; Xiuyan Wang; Elke Mühlberger; Viktor Volchkov; Jason Paragas; Hans-Dieter Klenk; Adolfo García-Sastre; Peter Palese
The Ebola virus VP35 protein functions as a type I IFN antagonist.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12289-94.
2000: A Feldmann; M K Schäfer; Wolfgang Garten; Hans-Dieter Klenk
Targeted infection of endothelial cells by avian influenza virus A/FPV/Rostock/34 (H7N1) in chicken embryos.
Journal of virology 2000;74(17):8018-27.
2000: Andréa Dessen; Viktor Volchkov; Olga Dolnik; Hans-Dieter Klenk; Winfried Weissenhorn
Crystal structure of the matrix protein VP40 from Ebola virus.
The EMBO journal 2000;19(16):4228-36.
2000: Ralf Wagner; Thorsten Wolff; Astrid Herwig; Stephan Pleschka; Hans-Dieter Klenk
Interdependence of hemagglutinin glycosylation and neuraminidase as regulators of influenza virus growth: a study by reverse genetics.
Journal of virology 2000;74(14):6316-23.
2000: Rob W H Ruigrok; Guy Schoehn; Andréa Dessen; Eric Forest; Viktor Volchkov; Olga Dolnik; Hans-Dieter Klenk; Winfried Weissenhorn
Structural characterization and membrane binding properties of the matrix protein VP40 of Ebola virus.
Journal of molecular biology 2000;300(1):103-12.
2000: A Berting; C Fischer; Stephan Schaefer; Wolfgang Garten; Hans-Dieter Klenk; W H Gerlich
Hemifusion activity of a chimeric influenza virus hemagglutinin with a putative fusion peptide from hepatitis B virus.
Virus research 2000;68(1):35-49.
2000: Andréa Dessen; Eric Forest; Viktor Volchkov; Olga Dolnik; Hans-Dieter Klenk; Winfried Weissenhorn
Crystallization and preliminary X-ray analysis of the matrix protein from Ebola virus.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 6):758-60.
2000: Viktor Volchkov; Valentina Volchkova; Ute Ströher; Stephan Becker; Olga Dolnik; M Cieplik; Wolfgang Garten; Hans-Dieter Klenk; Heinz Feldmann
Proteolytic processing of Marburg virus glycoprotein.
Virology 2000;268(1):1-6.
2000: C Krempl; ML Ballesteros; Gert Zimmer; Luis Enjuanes; Hans-Dieter Klenk; Georg Herrler
Characterization of the sialic acid binding activity of transmissible gastroenteritis coronavirus by analysis of haemagglutination-deficient mutants.
The Journal of general virology 2000;81(Pt 2):489-96.
2000: Andrea Maisner; B Mrkic; Georg Herrler; Markus Moll; Martin A Billeter; Roberto Cattaneo; Hans-Dieter Klenk
Recombinant measles virus requiring an exogenous protease for activation of infectivity.
The Journal of general virology 2000;81(Pt 2):441-9.
2000: Nahid Azzouz; Mamdouh H Kedees; Peter Gerold; S Becker; Jean-François Dubremetz; Hans-Dieter Klenk; Volker Eckert; Ralph T Schwarz
An early step of glycosylphosphatidyl-inositol anchor biosynthesis is abolished in lepidopteran insect cells following baculovirus infection.
Glycobiology 2000;10(2):177-83.
2000: Mamdouh H Kedees; Peter Gerold; Nahid Azzouz; Thomas Blaschke; Hosam Shams-Eldin; E Mühlberger; Anthony A Holder; Hans-Dieter Klenk; Ralph T Schwarz; Volker Eckert
Processing and localisation of a GPI-anchored Plasmodium falciparum surface protein expressed by the baculovirus system.
European journal of cell biology 2000;79(1):52-61.
1999: M Teuchert; S Berghöfer; Hans-Dieter Klenk; Wolfgang Garten
Recycling of furin from the plasma membrane. Functional importance of the cytoplasmic tail sorting signals and interaction with the AP-2 adaptor medium chain subunit.
The Journal of biological chemistry 1999;274(51):36781-9.
1999: Valentina Volchkova; Hans-Dieter Klenk; Viktor Volchkov
Delta-peptide is the carboxy-terminal cleavage fragment of the nonstructural small glycoprotein sGP of Ebola virus.
Virology 1999;265(1):164-71.
1999: Gert Zimmer; Frank Oeffner; Veronika von Messling; T Tschernig; H J Gröness; Hans-Dieter Klenk; Georg Herrler
Cloning and characterization of gp36, a human mucin-type glycoprotein preferentially expressed in vascular endothelium.
The Biochemical journal 1999;341 ( Pt 2)():277-84.
1999: Andreas Heiske; Bärbel Anheier; J Pilaski; Hans-Dieter Klenk; Hermann-Josef Gröne; Heinz Feldmann
Polymerase chain reaction detection of Puumala virus RNA in formaldehyde-fixed biopsy material.
Kidney international 1999;55(5):2062-9.
1999: M Teuchert; W Schäfer; S Berghöfer; B Hoflack; Hans-Dieter Klenk; Wolfgang Garten
Sorting of furin at the trans-Golgi network. Interaction of the cytoplasmic tail sorting signals with AP-1 Golgi-specific assembly proteins.
The Journal of biological chemistry 1999;274(12):8199-207.
1999: A Stroh; W Schäfer; S Berghöfer; Markus Eickmann; M Teuchert; I Bürger; Hans-Dieter Klenk; Wolfgang Garten
A mono phenylalanine-based motif (F790) and a leucine-dependent motif (LI760) mediate internalization of furin.
European journal of cell biology 1999;78(3):151-60.
1999: Wolfgang Garten; Hans-Dieter Klenk
Understanding influenza virus pathogenicity.
Trends in microbiology 1999;7(3):99-100.
1999: Beate Lötfering; Elke Mühlberger; T Tamura; Hans-Dieter Klenk; Stephan Becker
The nucleoprotein of Marburg virus is target for multiple cellular kinases.
Virology 1999;255(1):50-62.
1999: Elke Mühlberger; Michael Weik; Viktor Volchkov; Hans-Dieter Klenk; Stephan Becker
Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems.
Journal of virology 1999;73(3):2333-42.
1999: Frank Oeffner; Hans-Dieter Klenk; Georg Herrler
The cytoplasmic tail of the influenza C virus glycoprotein HEF negatively affects transport to the cell surface.
The Journal of general virology 1999;80 ( Pt 2)():363-9.
1999: Heinz Feldmann; Viktor Volchkov; Valentina Volchkova; Hans-Dieter Klenk
The glycoproteins of Marburg and Ebola virus and their potential roles in pathogenesis.
Archives of virology. Supplementum 1999;15():159-69.
1999: N V Kaverin; Hans-Dieter Klenk
Strain-specific differences in the effect of influenza A virus neuraminidase on vector-expressed hemagglutinin.
Archives of virology 1999;144(4):781-6.
1998: M Cieplik; Hans-Dieter Klenk; Wolfgang Garten
Identification and characterization of spodoptera frugiperda furin: a thermostable subtilisin-like endopeptidase.
Biological chemistry 1998;379(12):1433-40.
1998: Elke Mühlberger; Beate Lötfering; Hans-Dieter Klenk; Stephan Becker
Three of the four nucleocapsid proteins of Marburg virus, NP, VP35, and L, are sufficient to mediate replication and transcription of Marburg virus-specific monocistronic minigenomes.
Journal of virology 1998;72(11):8756-64.
1998: Valentina Volchkova; Heinz Feldmann; Hans-Dieter Klenk; Viktor Volchkov
The nonstructural small glycoprotein sGP of Ebola virus is secreted as an antiparallel-orientated homodimer.
Virology 1998;250(2):408-14.
1998: S Adler; P Reay; P Roy; Hans-Dieter Klenk
Induction of T cell response by bluetongue virus core-like particles expressing a T cell epitope of the M1 protein of influenza A virus.
Medical microbiology and immunology 1998;187(2):91-6.
1998: Stephan Becker; C Rinne; U Hofsäss; Hans-Dieter Klenk; Elke Mühlberger
Interactions of Marburg virus nucleocapsid proteins.
Virology 1998;249(2):406-17.
1998: C Fischer; B Schroth-Diez; A Herrmann; Wolfgang Garten; Hans-Dieter Klenk
Acylation of the influenza hemagglutinin modulates fusion activity.
Virology 1998;248(2):284-94.
1998: Andrea Maisner; Hans-Dieter Klenk; Georg Herrler
Polarized budding of measles virus is not determined by viral surface glycoproteins.
Journal of virology 1998;72(6):5276-8.
1998: Viktor Volchkov; Valentina Volchkova; Werner Slenczka; Hans-Dieter Klenk; Heinz Feldmann
Release of viral glycoproteins during Ebola virus infection.
Virology 1998;245(1):110-9.
1998: Viktor Volchkov; Heinz Feldmann; Valentina Volchkova; Hans-Dieter Klenk
Processing of the Ebola virus glycoprotein by the proprotein convertase furin.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5762-7.
1998: Masanobu Ohuchi; C Fischer; Reiko Ohuchi; Astrid Herwig; Hans-Dieter Klenk
Elongation of the cytoplasmic tail interferes with the fusion activity of influenza virus hemagglutinin.
Journal of virology 1998;72(5):3554-9.
1997: J Hausmann; E Kretzschmar; Wolfgang Garten; Hans-Dieter Klenk
Biosynthesis, intracellular transport and enzymatic activity of an avian influenza A virus neuraminidase: role of unpaired cysteines and individual oligosaccharides.
The Journal of general virology 1997;78 ( Pt 12)():3233-45.
1997: Masanobu Ohuchi; Reiko Ohuchi; A Feldmann; Hans-Dieter Klenk
Regulation of receptor binding affinity of influenza virus hemagglutinin by its carbohydrate moiety.
Journal of virology 1997;71(11):8377-84.
1997: Gert Zimmer; F Lottspeich; Andrea Maisner; Hans-Dieter Klenk; Georg Herrler
Molecular characterization of gp40, a mucin-type glycoprotein from the apical plasma membrane of Madin-Darby canine kidney cells (type I).
The Biochemical journal 1997;326 ( Pt 1)():99-108.
1997: Viktor Volchkov; Valentina Volchkova; C Eckel; Hans-Dieter Klenk; M Bouloy; B LeGuenno; Heinz Feldmann
Emergence of subtype Zaire Ebola virus in Gabon.
Virology 1997;232(1):139-44.
1997: Reiko Ohuchi; Masanobu Ohuchi; Wolfgang Garten; Hans-Dieter Klenk
Oligosaccharides in the stem region maintain the influenza virus hemagglutinin in the metastable form required for fusion activity.
Journal of virology 1997;71(5):3719-25.
1997: K Höfling; Hans-Dieter Klenk; Georg Herrler
Inactivation of inhibitors by the receptor-destroying enzyme of influenza C virus.
The Journal of general virology 1997;78 ( Pt 3)():567-70.
1997: S Hallenberger; M Moulard; M Sordel; Hans-Dieter Klenk; Wolfgang Garten
The role of eukaryotic subtilisin-like endoproteases for the activation of human immunodeficiency virus glycoproteins in natural host cells.
Journal of virology 1997;71(2):1036-45.
1996: Elke Mühlberger; S Trommer; C Funke; Viktor Volchkov; Hans-Dieter Klenk; Stephan Becker
Termini of all mRNA species of Marburg virus: sequence and secondary structure.
Virology 1996;223(2):376-80.
1996: R Wagner; H Geyer; Rudolf Geyer; Hans-Dieter Klenk
N-acetyl-beta-glucosaminidase accounts for differences in glycosylation of influenza virus hemagglutinin expressed in insect cells from a baculovirus vector.
Journal of virology 1996;70(6):4103-9.
1996: Heinz Feldmann; H Bugany; F Mahner; Hans-Dieter Klenk; Detlev Drenckhahn; Hans-Joachim Schnittler
Filovirus-induced endothelial leakage triggered by infected monocytes/macrophages.
Journal of virology 1996;70(4):2208-14.
1996: K Höfling; Reinhard Brossmer; Hans-Dieter Klenk; Georg Herrler
Transfer of an esterase-resistant receptor analog to the surface of influenza C virions results in reduced infectivity due to aggregate formation.
Virology 1996;218(1):127-33.
1996: R Wagner; S Liedtke; E Kretzschmar; Hildegard Geyer; Rudolf Geyer; Hans-Dieter Klenk
Elongation of the N-glycans of fowl plague virus hemagglutinin expressed in Spodoptera frugiperda (Sf9) cells by coexpression of human beta 1,2-N-acetylglucosaminyltransferase I.
Glycobiology 1996;6(2):165-75.
1996: Heinz Feldmann; Hans-Dieter Klenk
Marburg and Ebola viruses.
Advances in virus research 1996;47():1-52.
1996: Heinz Feldmann; Werner Slenczka; Hans-Dieter Klenk
Emerging and reemerging of filoviruses.
Archives of virology. Supplementum 1996;11():77-100.
1996: N V Kaverin; Masanobu Ohuchi; Reiko Ohuchi; Hans-Dieter Klenk
Phenotypic mixing with recombinant haemagglutinin of high cleavability mediates multi-cycle replication of human influenza virus in cell culture.
The Journal of general virology 1996;77 ( Pt 1)():119-22.
1995: Viktor Volchkov; S Becker; Valentina Volchkova; V A Ternovoj; A N Kotov; Sergey V Netesov; Hans-Dieter Klenk
GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases.
Virology 1995;214(2):421-30.
1995: S Pleschka; Hans-Dieter Klenk; Georg Herrler
The catalytic triad of the influenza C virus glycoprotein HEF esterase: characterization by site-directed mutagenesis and functional analysis.
The Journal of general virology 1995;76 ( Pt 10)():2529-37.
1995: M Itoh; P Hetterich; Rainer Isecke; Reinhard Brossmer; Hans-Dieter Klenk
Suppression of influenza virus infection by an N-thioacetylneuraminic acid acrylamide copolymer resistant to neuraminidase.
Virology 1995;212(2):340-7.
1995: Masanobu Ohuchi; A Feldmann; Reiko Ohuchi; Hans-Dieter Klenk
Neuraminidase is essential for fowl plague virus hemagglutinin to show hemagglutinating activity.
Virology 1995;212(1):77-83.
1995: Gert Zimmer; Hans-Dieter Klenk; Georg Herrler
Identification of a 40-kDa cell surface sialoglycoprotein with the characteristics of a major influenza C virus receptor in a Madin-Darby canine kidney cell line.
The Journal of biological chemistry 1995;270(30):17815-22.
1995: J Hausmann; E Kretzschmar; Wolfgang Garten; Hans-Dieter Klenk
N1 neuraminidase of influenza virus A/FPV/Rostock/34 has haemadsorbing activity.
The Journal of general virology 1995;76 ( Pt 7)():1719-28.
1995: W Schäfer; A Stroh; S Berghöfer; J Seiler; M Vey; M L Kruse; H F Kern; Hans-Dieter Klenk; Wolfgang Garten
Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin.
The EMBO journal 1995;14(11):2424-35.
1995: C Funke; Stephan Becker; H Dartsch; Hans-Dieter Klenk; Elke Mühlberger
Acylation of the Marburg virus glycoprotein.
Virology 1995;208(1):289-97.
1995: John W M Creemers; M Vey; W Schäfer; Torik A Y Ayoubi; Anton J M Roebroek; Hans-Dieter Klenk; Wolfgang Garten; Wim J M Van De Ven
Endoproteolytic cleavage of its propeptide is a prerequisite for efficient transport of furin out of the endoplasmic reticulum.
The Journal of biological chemistry 1995;270(6):2695-702.
1995: Stephan Becker; M Spiess; Hans-Dieter Klenk
The asialoglycoprotein receptor is a potential liver-specific receptor for Marburg virus.
The Journal of general virology 1995;76 ( Pt 2)():393-9.
1995: M Vey; W Schäfer; B Reis; Reiko Ohuchi; W Britt; Wolfgang Garten; Hans-Dieter Klenk; Klaus Radsak
Proteolytic processing of human cytomegalovirus glycoprotein B (gpUL55) is mediated by the human endoprotease furin.
Virology 1995;206(1):746-9.
1995: E Kretzschmar; K Kuroda; Hans-Dieter Klenk
Expression of the hemagglutinin protein of influenza virus. Analysis of protein modifications.
Methods in molecular biology (Clifton, N.J.) 1995;39():317-36.
1994: M Vey; W Schäfer; S Berghöfer; Hans-Dieter Klenk; Wolfgang Garten
Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation.
The Journal of cell biology 1994;127(6 Pt 2):1829-42.
1994: R Boycott; Hans-Dieter Klenk; Masanobu Ohuchi
Cell tropism of influenza virus mediated by hemagglutinin activation at the stage of virus entry.
Virology 1994;203(2):313-9.
1994: S Szepanski; Michael Veit; S Pleschka; Hans-Dieter Klenk; Michael F G Schmidt; Georg Herrler
Post-translational folding of the influenza C virus glycoprotein HEF: defective processing in cells expressing the cloned gene.
The Journal of general virology 1994;75 ( Pt 5)():1023-30.
1994: E Kretzchmar; Rudolf Geyer; Hans-Dieter Klenk
Baculovirus infection does not alter N-glycosylation in Spodoptera frugiperda cells.
Biological chemistry Hoppe-Seyler 1994;375(5):23-7.
1994: D Ortmann; Masanobu Ohuchi; H Angliker; E Shaw; Wolfgang Garten; Hans-Dieter Klenk
Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2.
Journal of virology 1994;68(4):2772-6.
1994: Masanobu Ohuchi; A Cramer; M Vey; Reiko Ohuchi; Wolfgang Garten; Hans-Dieter Klenk
Rescue of vector-expressed fowl plague virus hemagglutinin in biologically active form by acidotropic agents and coexpressed M2 protein.
Journal of virology 1994;68(2):920-6.
1994: Hans-Dieter Klenk; Wolfgang Garten
Host cell proteases controlling virus pathogenicity.
Trends in microbiology 1994;2(2):39-43.
1994: Wolfgang Garten; S Hallenberger; D Ortmann; W Schäfer; M Vey; H Angliker; E Shaw; Hans-Dieter Klenk
Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones.
Biochimie 1994;76(3-4):217-25.
1993: D Machytka; I Kharitonenkov; Rainer Isecke; P Hetterich; Reinhard Brossmer; R A Klein; Hans-Dieter Klenk; H Egge
Methyl alpha-glycoside of N-thioacetyl-D-neuraminic acid: a potential inhibitor of influenza A virus. A 1H NMR study.
FEBS letters 1993;334(1):117-20.
1993: P C Roberts; Wolfgang Garten; Hans-Dieter Klenk
Role of conserved glycosylation sites in maturation and transport of influenza A virus hemagglutinin.
Journal of virology 1993;67(6):3048-60.
1993: Hans-Joachim Schnittler; F Mahner; Detlev Drenckhahn; Hans-Dieter Klenk; Heinz Feldmann
Replication of Marburg virus in human endothelial cells. A possible mechanism for the development of viral hemorrhagic disease.
The Journal of clinical investigation 1993;91(4):1301-9.
1993: Cindy L Will; Elke Mühlberger; D Linder; Werner Slenczka; Hans-Dieter Klenk; Heinz Feldmann
Marburg virus gene 4 encodes the virion membrane protein, a type I transmembrane glycoprotein.
Journal of virology 1993;67(3):1203-10.
1993: Heinz Feldmann; Hans-Dieter Klenk; A Sanchez
Molecular biology and evolution of filoviruses.
Archives of virology. Supplementum 1993;7():81-100.
1992: S Hallenberger; V Bosch; H Angliker; E Shaw; Hans-Dieter Klenk; Wolfgang Garten
Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160.
Nature 1992;360(6402):358-61.
1992: Hildegard Geyer; C Will; H Feldmann; Hans-Dieter Klenk; Rudolf Geyer
Carbohydrate structure of Marburg virus glycoprotein.
Glycobiology 1992;2(4):299-312.
1992: A Stieneke-Gröber; M Vey; H Angliker; E Shaw; Gary Thomas; C Roberts; Hans-Dieter Klenk; Wolfgang Garten
Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.
The EMBO journal 1992;11(7):2407-14.
1992: Heinz Feldmann; Elke Mühlberger; A Randolf; Cindy L Will; M P Kiley; A Sanchez; Hans-Dieter Klenk
Marburg virus, a filovirus: messenger RNAs, gene order, and regulatory elements of the replication cycle.
Virus research 1992;24(1):1-19.
1992: K Munk; E Pritzer; E Kretzschmar; B Gutte; Wolfgang Garten; Hans-Dieter Klenk
Carbohydrate masking of an antigenic epitope of influenza virus haemagglutinin independent of oligosaccharide size.
Glycobiology 1992;2(3):233-40.
1992: S Szepanski; H J Gross; Reinhard Brossmer; Hans-Dieter Klenk; Georg Herrler
A single point mutation of the influenza C virus glycoprotein (HEF) changes the viral receptor-binding activity.
Virology 1992;188(1):85-92.
1992: M Vey; M Orlich; S Adler; Hans-Dieter Klenk; R Rott; Wolfgang Garten
Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R.
Virology 1992;188(1):408-13.
1992: E Kretzschmar; Michael Veit; S Brunschön; K Kuroda; Hans-Dieter Klenk
Secretion of fowl plague virus haemagglutinin from insect cells requires elimination of both hydrophobic domains.
The Journal of general virology 1992;73 ( Pt 4)():839-48.
1992: Elke Mühlberger; A Sanchez; A Randolf; Cindy L Will; M P Kiley; Hans-Dieter Klenk; Heinz Feldmann
The nucleotide sequence of the L gene of Marburg virus, a filovirus: homologies with paramyxoviruses and rhabdoviruses.
Virology 1992;187(2):534-47.
1992: Wolfgang Garten; Cindy L Will; K Buckard; K Kuroda; D Ortmann; K Munk; C Scholtissek; Hans-Joachim Schnittler; Detlev Drenckhahn; Hans-Dieter Klenk
Structure and assembly of hemagglutinin mutants of fowl plague virus with impaired surface transport.
Journal of virology 1992;66(3):1495-505.
1991: Reiko Ohuchi; Masanobu Ohuchi; Wolfgang Garten; Hans-Dieter Klenk
Human influenza virus hemagglutinin with high sensitivity to proteolytic activation.
Journal of virology 1991;65(7):3530-7.
1991: Hans-Dieter Klenk; K Kuroda; E Kretzschmar; Rudolf Geyer; A Gröner; W Doerfler
Processing of influenza virus hemagglutinin in insect cells.
Behring Institute Mitteilungen 1991;(89):27-34.
1991: Wolfgang Garten; M Vey; Reiko Ohuchi; Masanobu Ohuchi; Hans-Dieter Klenk
Modification of the cleavage activation of the influenza virus hemagglutinin by site-specific mutagenesis.
Behring Institute Mitteilungen 1991;(89):12-22.
1991: Michael Veit; Hans-Dieter Klenk; A Kendal; R Rott
The M2 protein of influenza A virus is acylated.
The Journal of general virology 1991;72 ( Pt 6)():1461-5.
1991: Heinz Feldmann; Cindy L Will; M Schikore; Werner Slenczka; Hans-Dieter Klenk
Glycosylation and oligomerization of the spike protein of Marburg virus.
Virology 1991;182(1):353-6.
1991: Michael Veit; E Kretzschmar; K Kuroda; Wolfgang Garten; Michael F G Schmidt; Hans-Dieter Klenk; R Rott
Site-specific mutagenesis identifies three cysteine residues in the cytoplasmic tail as acylation sites of influenza virus hemagglutinin.
Journal of virology 1991;65(5):2491-500.
1991: B Schultze; K Wahn; Hans-Dieter Klenk; Georg Herrler
Isolated HE-protein from hemagglutinating encephalomyelitis virus and bovine coronavirus has receptor-destroying and receptor-binding activity.
Virology 1991;180(1):221-8.
1991: K Kuroda; Michael Veit; Hans-Dieter Klenk
Retarded processing of influenza virus hemagglutinin in insect cells.
Virology 1991;180(1):159-65.
1991: Georg Herrler; Hans-Dieter Klenk
Structure and function of the HEF glycoprotein of influenza C virus.
Advances in virus research 1991;40():213-34.
1991: A P Kendal; Hans-Dieter Klenk
Amantadine inhibits an early, M2 protein-dependent event in the replication cycle of avian influenza (H7) viruses.
Archives of virology 1991;119(3-4):265-73.
1990: K H Brücher; Wolfgang Garten; Hans-Dieter Klenk; E Shaw; Klaus Radsak
Inhibition of endoproteolytic cleavage of cytomegalovirus (HCMV) glycoprotein B by palmitoyl-peptidyl-chloromethyl ketone.
Virology 1990;178(2):617-20.
1990: Michael Veit; Georg Herrler; Michael F G Schmidt; R Rott; Hans-Dieter Klenk
The hemagglutinating glycoproteins of influenza B and C viruses are acylated with different fatty acids.
Virology 1990;177(2):807-11.
1990: B Schultze; H J Gross; Reinhard Brossmer; Hans-Dieter Klenk; Georg Herrler
Hemagglutinating encephalomyelitis virus attaches to N-acetyl-9-O-acetylneuraminic acid-containing receptors on erythrocytes: comparison with bovine coronavirus and influenza C virus.
Virus research 1990;16(2):185-94.
1990: E Pritzer; K Kuroda; Wolfgang Garten; Y Nagai; Hans-Dieter Klenk
A host range mutant of Newcastle disease virus with an altered cleavage site for proteolytic activation of the F protein.
Virus research 1990;15(3):237-42.
1990: K Kuroda; H Geyer; Rudolf Geyer; W Doerfler; Hans-Dieter Klenk
The oligosaccharides of influenza virus hemagglutinin expressed in insect cells by a baculovirus vector.
Virology 1990;174(2):418-29.
1990: B Schultze; H J Gross; Hans-Dieter Klenk; Reinhard Brossmer; Georg Herrler
Differential reactivity of bovine coronavirus (BCV) and influenza C virus with N-acetyl-9-O-acetylneuraminic acid (Neu5,9Ac2)-containing receptors.
Advances in experimental medicine and biology 1990;276():115-9.
1990: B Schultze; G Hess; R Rott; Hans-Dieter Klenk; Georg Herrler
Isolation and characterization of the acetylesterase of hemagglutinating encephalomyelitis virus (HEV).
Advances in experimental medicine and biology 1990;276():109-13.
1989: Wolfgang Garten; A Stieneke; E Shaw; P Wikstrom; Hans-Dieter Klenk
Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones.
Virology 1989;172(1):25-31.
1989: K Kuroda; A Gröner; K Frese; Detlev Drenckhahn; C Hauser; R Rott; W Doerfler; Hans-Dieter Klenk
Synthesis of biologically active influenza virus hemagglutinin in insect larvae.
Journal of virology 1989;63(4):1677-85.
1989: Masanobu Ohuchi; M Orlich; Reiko Ohuchi; B E Simpson; Wolfgang Garten; Hans-Dieter Klenk; R Rott
Mutations at the cleavage site of the hemagglutinin after the pathogenicity of influenza virus A/chick/Penn/83 (H5N2).
Virology 1989;168(2):274-80.
1988: Heinz Feldmann; E Kretzschmar; B Klingeborn; R Rott; Hans-Dieter Klenk; Wolfgang Garten
The structure of serotype H10 hemagglutinin of influenza A virus: comparison of an apathogenic avian and a mammalian strain pathogenic for mink.
Virology 1988;165(2):428-37.
1988: Georg Herrler; I Dürkop; H Becht; Hans-Dieter Klenk
The glycoprotein of influenza C virus is the haemagglutinin, esterase and fusion factor.
The Journal of general virology 1988;69 ( Pt 4)():839-46.
1988: Georg Herrler; Gerd Multhaup; Konrad Beyreuther; Hans-Dieter Klenk
Serine 71 of the glycoprotein HEF is located at the active site of the acetylesterase of influenza C virus.
Archives of virology 1988;102(3-4):269-74.
1988: Hans-Dieter Klenk; R Rott
The molecular biology of influenza virus pathogenicity.
Advances in virus research 1988;34():247-81.
1986: W Schuy; Cindy L Will; K Kuroda; C Scholtissek; Wolfgang Garten; Hans-Dieter Klenk
Mutations blocking the transport of the influenza virus hemagglutinin between the rough endoplasmic reticulum and the Golgi apparatus.
The EMBO journal 1986;5(11):2831-6.
1985: Wolfgang Garten; K Kuroda; W Schuy; H Naruse; C Scholtissek; Hans-Dieter Klenk
Haemagglutinin transport mutants.
Vaccine 1985;3(3 Suppl):227-9.
1984: W Schuy; Wolfgang Garten; D Linder; Hans-Dieter Klenk
The carboxyterminus of the hemagglutinin-neuraminidase of Newcastle disease virus is exposed at the surface of the viral envelope.
Virus research 1984;1(5):415-26.