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Hans-Dieter Klenk

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Co-Publications
Name
50
Garten, Wolfgang
25
Feldmann, Heinz
22
Volchkov, Viktor
21
Herrler, Georg
20
Becker, Stephan
18
Mühlberger, Elke
14
Volchkova, Valentina
11
Ohuchi, Masanobu
11
Maisner, Andrea
11
Matrosovich, Mikhail
10
Ohuchi, Reiko
8
Rott, R
8
Matrosovich, Tatyana
8
Moll, Markus
7
Herwig, Astrid

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Publications

TOP 3
Böttcher Eva; Freuer Catharina; Steinmetzer Torsten; Klenk Hans-Dieter; Garten Wolfgang
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.
Maisa Anna; Ströher Ute; Klenk Hans-Dieter; Garten Wolfgang; Strecker Thomas
Inhibition of Lassa Virus Glycoprotein Cleavage and Multicycle Replication by Site 1 Protease-Adapted alpha(1)-Antitrypsin Variants.
Uhlendorff Jennifer; Matrosovich Tatyana; Klenk Hans-Dieter; Matrosovich Mikhail
Functional significance of the hemadsorption activity of influenza virus neuraminidase and its alteration in pandemic viruses.

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All Publications

2009: Böttcher Eva; Freuer Catharina; Steinmetzer Torsten; Klenk Hans-Dieter; Garten Wolfgang
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.
Vaccine 2009;27(45):6324-9.
2009: Maisa Anna; Ströher Ute; Klenk Hans-Dieter; Garten Wolfgang; Strecker Thomas
Inhibition of Lassa Virus Glycoprotein Cleavage and Multicycle Replication by Site 1 Protease-Adapted alpha(1)-Antitrypsin Variants.
PLoS neglected tropical diseases 2009;3(6):e446.
2009: Uhlendorff Jennifer; Matrosovich Tatyana; Klenk Hans-Dieter; Matrosovich Mikhail
Functional significance of the hemadsorption activity of influenza virus neuraminidase and its alteration in pandemic viruses.
Archives of virology 2009;154(6):945-57.
2008: Stech Jürgen; Stech Olga; Herwig Astrid; Altmeppen Hermann; Hundt Jana; Gohrbandt Sandra; Kreibich Anne; Weber Siegfried; Klenk Hans-Dieter; Mettenleiter Thomas C
Rapid and reliable universal cloning of influenza A virus genes by target-primed plasmid amplification.
Nucleic acids research 2008;36(21):e139.
2008: Gabriel Gülsah; Nordmann Alexandra; Stein David A; Iversen Patrick L; Klenk Hans-Dieter
Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus.
The Journal of general virology 2008;89(Pt 4):939-48.
2008: Runkler Nicole; Dietzel Erik; Moll Markus; Klenk Hans-Dieter; Maisner Andrea
Glycoprotein targeting signals influence the distribution of measles virus envelope proteins and virus spread in lymphocytes.
The Journal of general virology 2008;89(Pt 3):687-96.
2008: Gabriel Gülsah; Herwig Astrid; Klenk Hans-Dieter
Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus.
PLoS pathogens 2008;4(2):e11.
2008: Gabriel G; Garn H; Wegmann M; Renz H; Herwig A; Klenk H-D; Stech J
The potential of a protease activation mutant of a highly pathogenic avian influenza virus for a pandemic live vaccine.
Vaccine 2008;26(7):956-65.
2007: Jones Steven M; Stroher Ute; Fernando Lisa; Qiu Xianggou; Alimonti Judie; Melito Pasquale; Bray Mike; Klenk Hans-Dieter; Feldmann Heinz
Assessment of a vesicular stomatitis virus-based vaccine by use of the mouse model of Ebola virus hemorrhagic fever.
The Journal of infectious diseases 2007;196 Suppl 2():S404-12.
2007: Slenczka Werner; Klenk Hans Dieter
Forty years of marburg virus.
The Journal of infectious diseases 2007;196 Suppl 2():S131-5.
2007: Gabriel G; Abram M; Keiner B; Wagner R; Klenk H-D; Stech J
Differential polymerase activity in avian and mammalian cells determines host range of influenza virus.
Journal of virology 2007;81(17):9601-4.
2007: Runkler Nicole; Pohl Christine; Schneider-Schaulies Sibylle; Klenk Hans-Dieter; Maisner Andrea
Measles virus nucleocapsid transport to the plasma membrane requires stable expression and surface accumulation of the viral matrix protein.
Cellular microbiology 2007;9(5):1203-14.
2007: Matrosovich Mikhail; Matrosovich Tatyana; Uhlendorff Jennifer; Garten Wolfgang; Klenk Hans-Dieter
Avian-virus-like receptor specificity of the hemagglutinin impedes influenza virus replication in cultures of human airway epithelium.
Virology 2007;361(2):384-90.
2006: Böttcher Eva; Matrosovich Tatyana; Beyerle Michaela; Klenk Hans-Dieter; Garten Wolfgang; Matrosovich Mikhail
Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium.
Journal of virology 2006;80(19):9896-8.
2006: Marjuki Henju; Alam Mohammad I; Ehrhardt Christina; Wagner Ralf; Planz Oliver; Klenk Hans-D; Ludwig Stephan; Pleschka Stephan
Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling.
The Journal of biological chemistry 2006;281(24):16707-15.
2006: Stech Jürgen; Klenk Hans-Dieter
A new approach to an influenza life vaccine: haemagglutinin cleavage site mutants generated by reverse genetics.
Berliner und Münchener tierärztliche Wochenschrift 2006;119(3-4):186-91.
2006: Matrosovich Mikhail; Suzuki Takashi; Hirabayashi Yoshio; Garten Wolfgang; Webster Robert G; Klenk Hans-Dieter
Gangliosides are not essential for influenza virus infection.
Glycoconjugate journal 2006;23(1-2):107-13.
2006: Enterlein Sven; Volchkov Viktor; Weik Michael; Kolesnikova Larissa; Volchkova Valentina; Klenk Hans-Dieter; Mühlberger Elke
Rescue of recombinant Marburg virus from cDNA is dependent on nucleocapsid protein VP30.
Journal of virology 2006;80(2):1038-43.
2006: Matrosovich Mikhail; Matrosovich Tatyana; Garten Wolfgang; Klenk Hans-Dieter
New low-viscosity overlay medium for viral plaque assays.
Virology journal 2006;3():63.
2005: Gabriel G; Dauber B; Wolff T; Planz O; Klenk H-D; Stech J
The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(51):18590-5.
2005: Möller Peggy; Pariente Nonia; Klenk Hans-Dieter; Becker Stephan
Homo-oligomerization of Marburgvirus VP35 is essential for its function in replication and transcription.
Journal of virology 2005;79(23):14876-86.
2005: Gambaryan A S; Boravleva E Y; Matrosovich T Y; Matrosovich M N; Klenk H-D; Moiseeva E V; Tuzikov A B; Chinarev A A; Pazynina G V; Bovin N V
Polymer-bound 6' sialyl-N-acetyllactosamine protects mice infected by influenza virus.
Antiviral research 2005;68(3):116-23.
2005: Bamberg Sandra; Kolesnikova Larissa; Möller Peggy; Klenk Hans-Dieter; Becker Stephan
VP24 of Marburg virus influences formation of infectious particles.
Journal of virology 2005;79(21):13421-33.
2005: Klenk Hans-Dieter
Infection of the endothelium by influenza viruses.
Thrombosis and haemostasis 2005;94(2):262-5.
2005: Diederich Sandra; Moll Markus; Klenk Hans-Dieter; Maisner Andrea
The nipah virus fusion protein is cleaved within the endosomal compartment.
The Journal of biological chemistry 2005;280(33):29899-903.
2005: Jones Steven M; Feldmann Heinz; Ströher Ute; Geisbert Joan B; Fernando Lisa; Grolla Allen; Klenk Hans-Dieter; Sullivan Nancy J; Volchkov Viktor E; Fritz Elizabeth A; Daddario Kathleen M; Hensley Lisa E; Jahrling Peter B; Geisbert Thomas W
Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses.
Nature medicine 2005;11(7):786-90.
2005: Daffis Stephane; Kontermann Roland E; Korimbocus Jehanara; Zeller Hervé; Klenk Hans-Dieter; Ter Meulen Jan
Antibody responses against wild-type yellow fever virus and the 17D vaccine strain: characterization with human monoclonal antibody fragments and neutralization escape variants.
Virology 2005;337(2):262-72.
2005: Wagner Ralf; Herwig Astrid; Azzouz Nahid; Klenk Hans Dieter
Acylation-mediated membrane anchoring of avian influenza virus hemagglutinin is essential for fusion pore formation and virus infectivity.
Journal of virology 2005;79(10):6449-58.
2005: Volchkov Viktor E; Volchkova Valentina A; Dolnik Olga; Feldmann Heinz; Klenk Hans-Dieter
Polymorphism of filovirus glycoproteins.
Advances in virus research 2005;64():359-81.
2004: Matrosovich Mikhail N; Matrosovich Tatyana Y; Gray Thomas; Roberts Noel A; Klenk Hans-Dieter
Neuraminidase is important for the initiation of influenza virus infection in human airway epithelium.
Journal of virology 2004;78(22):12665-7.
2004: Moll Markus; Diederich Sandra; Klenk Hans-Dieter; Czub Markus; Maisner Andrea
Ubiquitous activation of the Nipah virus fusion protein does not require a basic amino acid at the cleavage site.
Journal of virology 2004;78(18):9705-12.
2004: Garbutt Michael; Liebscher Ryan; Wahl-Jensen Victoria; Jones Steven; Möller Peggy; Wagner Ralf; Volchkov Viktor; Klenk Hans-Dieter; Feldmann Heinz; Ströher Ute
Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses.
Journal of virology 2004;78(10):5458-65.
2004: Dolnik Olga; Volchkova Valentina; Garten Wolfgang; Carbonnelle Caroline; Becker Stephan; Kahnt Jörg; Ströher Ute; Klenk Hans-Dieter; Volchkov Viktor
Ectodomain shedding of the glycoprotein GP of Ebola virus.
The EMBO journal 2004;23(10):2175-84.
2004: Moll Markus; Pfeuffer Joanna; Klenk Hans-Dieter; Niewiesk Stefan; Maisner Andrea
Polarized glycoprotein targeting affects the spread of measles virus in vitro and in vivo.
The Journal of general virology 2004;85(Pt 4):1019-27.
2004: Matrosovich Mikhail N; Matrosovich Tatyana Y; Gray Thomas; Roberts Noel A; Klenk Hans-Dieter
Human and avian influenza viruses target different cell types in cultures of human airway epithelium.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4620-4.
2004: Eichler Robert; Strecker Thomas; Kolesnikova Larissa; ter Meulen Jan; Weissenhorn Winfried; Becker Stephan; Klenk Hans Dieter; Garten Wolfgang; Lenz Oliver
Characterization of the Lassa virus matrix protein Z: electron microscopic study of virus-like particles and interaction with the nucleoprotein (NP).
Virus research 2004;100(2):249-55.
2004: Eichler Robert; Lenz Oliver; Strecker Thomas; Eickmann Markus; Klenk Hans-Dieter; Garten Wolfgang
Lassa virus glycoprotein signal peptide displays a novel topology with an extended endoplasmic reticulum luminal region.
The Journal of biological chemistry 2004;279(13):12293-9.
2003: Klenk Hans-Dieter
In memoriam Rudolf Rott (1926-2003).
Archives of virology 2003;148(12):2489-91.
2003: Eichler Robert; Lenz Oliver; Strecker Thomas; Eickmann Markus; Klenk Hans-Dieter; Garten Wolfgang
Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor.
EMBO reports 2003;4(11):1084-8.
2003: Hartlieb Bettina; Modrof Jens; Mühlberger Elke; Klenk Hans-Dieter; Becker Stephan
Oligomerization of Ebola virus VP30 is essential for viral transcription and can be inhibited by a synthetic peptide.
The Journal of biological chemistry 2003;278(43):41830-6.
2003: Timmins Joanna; Schoehn Guy; Kohlhaas Christine; Klenk Hans-Dieter; Ruigrok Rob W H; Weissenhorn Winfríed
Oligomerization and polymerization of the filovirus matrix protein VP40.
Virology 2003;312(2):359-68.
2003: Matrosovich Mikhail; Matrosovich Tatyana; Carr Jackie; Roberts Noel A; Klenk Hans-Dieter
Overexpression of the alpha-2,6-sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitors.
Journal of virology 2003;77(15):8418-25.
2003: Basler Christopher F; Mikulasova Andrea; Martinez-Sobrido Luis; Paragas Jason; Mühlberger Elke; Bray Mike; Klenk Hans-Dieter; Palese Peter; García-Sastre Adolfo
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
Journal of virology 2003;77(14):7945-56.
2003: Gomis-Rüth F Xavier; Dessen Andréa; Timmins Joanna; Bracher Andreas; Kolesnikowa Larissa; Becker Stephan; Klenk Hans Dieter; Weissenhorn Winfried
The matrix protein VP40 from Ebola virus octamerizes into pore-like structures with specific RNA binding properties.
Structure (London, England : 1993) 2003;11(4):423-33.
2003: Matrosovich Mikhail; Klenk Hans-Dieter
Natural and synthetic sialic acid-containing inhibitors of influenza virus receptor binding.
Reviews in medical virology 2003;13(2):85-97.
2002: Wichmann Dominic; Gröne Hermann-Josef; Frese Michael; Pavlovic Jovan; Anheier Bärbel; Haller Otto; Klenk Hans-Dieter; Feldmann Heinz
Hantaan virus infection causes an acute neurological disease that is fatal in adult laboratory mice.
Journal of virology 2002;76(17):8890-9.
2002: Weik Michael; Modrof Jens; Klenk Hans-Dieter; Becker Stephan; Mühlberger Elke
Ebola virus VP30-mediated transcription is regulated by RNA secondary structure formation.
Journal of virology 2002;76(17):8532-9.
2002: Modrof Jens; Mühlberger Elke; Klenk Hans-Dieter; Becker Stephan
Phosphorylation of VP30 impairs ebola virus transcription.
The Journal of biological chemistry 2002;277(36):33099-104.
2002: Moll Markus; Klenk Hans-Dieter; Maisner Andrea
Importance of the cytoplasmic tails of the measles virus glycoproteins for fusogenic activity and the generation of recombinant measles viruses.
Journal of virology 2002;76(14):7174-86.
2002: Wagner Ralf; Matrosovich Mikhail; Klenk Hans-Dieter
Functional balance between haemagglutinin and neuraminidase in influenza virus infections.
Reviews in medical virology 2002;12(3):159-66.
2002: Sänger Christian; Mühlberger Elke; Lötfering Beate; Klenk Hans-Dieter; Becker Stephan
The Marburg virus surface protein GP is phosphorylated at its ectodomain.
Virology 2002;295(1):20-9.
2002: Wagner Ralf; Heuer Dagmar; Wolff Thorsten; Herwig Astrid; Klenk Hans-Dieter
N-Glycans attached to the stem domain of haemagglutinin efficiently regulate influenza A virus replication.
The Journal of general virology 2002;83(Pt 3):601-9.
2002: Riedl Petra; Moll Markus; Klenk Hans-Dieter; Maisner Andrea
Measles virus matrix protein is not cotransported with the viral glycoproteins but requires virus infection for efficient surface targeting.
Virus research 2002;83(1-2):1-12.
2002: Kolesnikova Larissa; Bugany Harald; Klenk Hans-Dieter; Becker Stephan
VP40, the matrix protein of Marburg virus, is associated with membranes of the late endosomal compartment.
Journal of virology 2002;76(4):1825-38.
2002: Klenk Hans-Dieter; Wagner Ralf; Heuer Dagmar; Wolff Thorsten
Importance of hemagglutinin glycosylation for the biological functions of influenza virus.
Virus research 2002;82(1-2):73-5.
2001: Feldmann H; Volchkov V E; Volchkova V A; Ströher U; Klenk H D
Biosynthesis and role of filoviral glycoproteins.
The Journal of general virology 2001;82(Pt 12):2839-48.
2001: Ströher U; West E; Bugany H; Klenk H D; Schnittler H J; Feldmann H
Infection and activation of monocytes by Marburg and Ebola viruses.
Journal of virology 2001;75(22):11025-33.
2001: Klenk H D; Feldmann H
Symposium on Marburg and Ebola viruses.
Virus research 2001;80(1-2):117-23.
2001: Löber C; Anheier B; Lindow S; Klenk H D; Feldmann H
The Hantaan virus glycoprotein precursor is cleaved at the conserved pentapeptide WAASA.
Virology 2001;289(2):224-9.
2001: Lenz O; ter Meulen J; Klenk H D; Seidah N G; Garten W
The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(22):12701-5.
2001: Moll M; Klenk H D; Herrler G; Maisner A
A single amino acid change in the cytoplasmic domains of measles virus glycoproteins H and F alters targeting, endocytosis, and cell fusion in polarized Madin-Darby canine kidney cells.
The Journal of biological chemistry 2001;276(21):17887-94.
2001: Volchkov V E; Volchkova V A; Muhlberger E; Kolesnikova L V; Weik M; Dolnik O; Klenk H D
Recovery of infectious Ebola virus from complementary DNA: RNA editing of the GP gene and viral cytotoxicity.
Science (New York, N.Y.) 2001;291(5510):1965-9.
2001: Sänger C; Mühlberger E; Ryabchikova E; Kolesnikova L; Klenk H D; Becker S
Sorting of Marburg virus surface protein and virus release take place at opposite surfaces of infected polarized epithelial cells.
Journal of virology 2001;75(3):1274-83.
2001: Sänger C; Mühlberger E; Klenk H D; Becker S
Adverse effects of MVA-T7 on the transport of Marburg virus glycoprotein.
Journal of virological methods 2001;91(1):29-35.
2000: Scianimanico S; Schoehn G; Timmins J; Ruigrok R H; Klenk H D; Weissenhorn W
Membrane association induces a conformational change in the Ebola virus matrix protein.
The EMBO journal 2000;19(24):6732-41.
2000: Lenz O; ter Meulen J; Feldmann H; Klenk H D; Garten W
Identification of a novel consensus sequence at the cleavage site of the Lassa virus glycoprotein.
Journal of virology 2000;74(23):11418-21.
2000: Volchkov V E; Chepurnov A A; Volchkova V A; Ternovoj V A; Klenk H D
Molecular characterization of guinea pig-adapted variants of Ebola virus.
Virology 2000;277(1):147-55.
2000: Basler C F; Wang X; Mühlberger E; Volchkov V; Paragas J; Klenk H D; García-Sastre A; Palese P
The Ebola virus VP35 protein functions as a type I IFN antagonist.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12289-94.
2000: Feldmann A; Schäfer M K; Garten W; Klenk H D
Targeted infection of endothelial cells by avian influenza virus A/FPV/Rostock/34 (H7N1) in chicken embryos.
Journal of virology 2000;74(17):8018-27.
2000: Dessen A; Volchkov V; Dolnik O; Klenk H D; Weissenhorn W
Crystal structure of the matrix protein VP40 from Ebola virus.
The EMBO journal 2000;19(16):4228-36.
2000: Wagner R; Wolff T; Herwig A; Pleschka S; Klenk H D
Interdependence of hemagglutinin glycosylation and neuraminidase as regulators of influenza virus growth: a study by reverse genetics.
Journal of virology 2000;74(14):6316-23.
2000: Berting A; Fischer C; Schaefer S; Garten W; Klenk H D; Gerlich W H
Hemifusion activity of a chimeric influenza virus hemagglutinin with a putative fusion peptide from hepatitis B virus.
Virus research 2000;68(1):35-49.
2000: Ruigrok R W; Schoehn G; Dessen A; Forest E; Volchkov V; Dolnik O; Klenk H D; Weissenhorn W
Structural characterization and membrane binding properties of the matrix protein VP40 of Ebola virus.
Journal of molecular biology 2000;300(1):103-12.
2000: Dessen A; Forest E; Volchkov V; Dolnik O; Klenk H D; Weissenhorn W
Crystallization and preliminary X-ray analysis of the matrix protein from Ebola virus.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 6):758-60.
2000: Volchkov V E; Volchkova V A; Ströher U; Becker S; Dolnik O; Cieplik M; Garten W; Klenk H D; Feldmann H
Proteolytic processing of Marburg virus glycoprotein.
Virology 2000;268(1):1-6.
2000: Krempl C; Ballesteros M L; Zimmer G; Enjuanes L; Klenk H D; Herrler G
Characterization of the sialic acid binding activity of transmissible gastroenteritis coronavirus by analysis of haemagglutination-deficient mutants.
The Journal of general virology 2000;81(Pt 2):489-96.
2000: Maisner A; Mrkic B; Herrler G; Moll M; Billeter M A; Cattaneo R; Klenk H D
Recombinant measles virus requiring an exogenous protease for activation of infectivity.
The Journal of general virology 2000;81(Pt 2):441-9.
2000: Azzouz N; Kedees M H; Gerold P; Becker S; Dubremetz J F; Klenk H D; Eckert V; Schwarz R T
An early step of glycosylphosphatidyl-inositol anchor biosynthesis is abolished in lepidopteran insect cells following baculovirus infection.
Glycobiology 2000;10(2):177-83.
2000: Kedees M H; Gerold P; Azzouz N; Blaschke T; Shams-Eldin H; Mühlberger E; Holder A A; Klenk H D; Schwarz R T; Eckert V
Processing and localisation of a GPI-anchored Plasmodium falciparum surface protein expressed by the baculovirus system.
European journal of cell biology 2000;79(1):52-61.
1999: Volchkova V A; Klenk H D; Volchkov V E
Delta-peptide is the carboxy-terminal cleavage fragment of the nonstructural small glycoprotein sGP of Ebola virus.
Virology 1999;265(1):164-71.
1999: Teuchert M; Berghöfer S; Klenk H D; Garten W
Recycling of furin from the plasma membrane. Functional importance of the cytoplasmic tail sorting signals and interaction with the AP-2 adaptor medium chain subunit.
The Journal of biological chemistry 1999;274(51):36781-9.
1999: Zimmer G; Oeffner F; Von Messling V; Tschernig T; Gröness H J; Klenk H D; Herrler G
Cloning and characterization of gp36, a human mucin-type glycoprotein preferentially expressed in vascular endothelium.
The Biochemical journal 1999;341 ( Pt 2)():277-84.
1999: Heiske A; Anheier B; Pilaski J; Klenk H D; Gröne H J; Feldmann H
Polymerase chain reaction detection of Puumala virus RNA in formaldehyde-fixed biopsy material.
Kidney international 1999;55(5):2062-9.
1999: Stroh A; Schäfer W; Berghöfer S; Eickmann M; Teuchert M; Bürger I; Klenk H D; Garten W
A mono phenylalanine-based motif (F790) and a leucine-dependent motif (LI760) mediate internalization of furin.
European journal of cell biology 1999;78(3):151-60.
1999: Garten W; Klenk H D
Understanding influenza virus pathogenicity.
Trends in microbiology 1999;7(3):99-100.
1999: Teuchert M; Schäfer W; Berghöfer S; Hoflack B; Klenk H D; Garten W
Sorting of furin at the trans-Golgi network. Interaction of the cytoplasmic tail sorting signals with AP-1 Golgi-specific assembly proteins.
The Journal of biological chemistry 1999;274(12):8199-207.
1999: Lötfering B; Mühlberger E; Tamura T; Klenk H D; Becker S
The nucleoprotein of Marburg virus is target for multiple cellular kinases.
Virology 1999;255(1):50-62.
1999: Mühlberger E; Weik M; Volchkov V E; Klenk H D; Becker S
Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems.
Journal of virology 1999;73(3):2333-42.
1999: Oeffner F; Klenk H D; Herrler G
The cytoplasmic tail of the influenza C virus glycoprotein HEF negatively affects transport to the cell surface.
The Journal of general virology 1999;80 ( Pt 2)():363-9.
1999: Feldmann H; Volchkov V E; Volchkova V A; Klenk H D
The glycoproteins of Marburg and Ebola virus and their potential roles in pathogenesis.
Archives of virology. Supplementum 1999;15():159-69.
1999: Kaverin N V; Klenk H D
Strain-specific differences in the effect of influenza A virus neuraminidase on vector-expressed hemagglutinin.
Archives of virology 1999;144(4):781-6.
1998: Cieplik M; Klenk H D; Garten W
Identification and characterization of spodoptera frugiperda furin: a thermostable subtilisin-like endopeptidase.
Biological chemistry 1998;379(12):1433-40.
1998: Mühlberger E; Lötfering B; Klenk H D; Becker S
Three of the four nucleocapsid proteins of Marburg virus, NP, VP35, and L, are sufficient to mediate replication and transcription of Marburg virus-specific monocistronic minigenomes.
Journal of virology 1998;72(11):8756-64.
1998: Adler S; Reay P; Roy P; Klenk H D
Induction of T cell response by bluetongue virus core-like particles expressing a T cell epitope of the M1 protein of influenza A virus.
Medical microbiology and immunology 1998;187(2):91-6.
1998: Volchkova V A; Feldmann H; Klenk H D; Volchkov V E
The nonstructural small glycoprotein sGP of Ebola virus is secreted as an antiparallel-orientated homodimer.
Virology 1998;250(2):408-14.
1998: Becker S; Rinne C; Hofsäss U; Klenk H D; Mühlberger E
Interactions of Marburg virus nucleocapsid proteins.
Virology 1998;249(2):406-17.
1998: Fischer C; Schroth-Diez B; Herrmann A; Garten W; Klenk H D
Acylation of the influenza hemagglutinin modulates fusion activity.
Virology 1998;248(2):284-94.
1998: Maisner A; Klenk H; Herrler G
Polarized budding of measles virus is not determined by viral surface glycoproteins.
Journal of virology 1998;72(6):5276-8.
1998: Volchkov V E; Volchkova V A; Slenczka W; Klenk H D; Feldmann H
Release of viral glycoproteins during Ebola virus infection.
Virology 1998;245(1):110-9.
1998: Volchkov V E; Feldmann H; Volchkova V A; Klenk H D
Processing of the Ebola virus glycoprotein by the proprotein convertase furin.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5762-7.
1998: Ohuchi M; Fischer C; Ohuchi R; Herwig A; Klenk H D
Elongation of the cytoplasmic tail interferes with the fusion activity of influenza virus hemagglutinin.
Journal of virology 1998;72(5):3554-9.
1997: Hausmann J; Kretzschmar E; Garten W; Klenk H D
Biosynthesis, intracellular transport and enzymatic activity of an avian influenza A virus neuraminidase: role of unpaired cysteines and individual oligosaccharides.
The Journal of general virology 1997;78 ( Pt 12)():3233-45.
1997: Ohuchi M; Ohuchi R; Feldmann A; Klenk H D
Regulation of receptor binding affinity of influenza virus hemagglutinin by its carbohydrate moiety.
Journal of virology 1997;71(11):8377-84.
1997: Zimmer G; Lottspeich F; Maisner A; Klenk H D; Herrler G
Molecular characterization of gp40, a mucin-type glycoprotein from the apical plasma membrane of Madin-Darby canine kidney cells (type I).
The Biochemical journal 1997;326 ( Pt 1)():99-108.
1997: Volchkov V; Volchkova V; Eckel C; Klenk H D; Bouloy M; LeGuenno B; Feldmann H
Emergence of subtype Zaire Ebola virus in Gabon.
Virology 1997;232(1):139-44.
1997: Ohuchi R; Ohuchi M; Garten W; Klenk H D
Oligosaccharides in the stem region maintain the influenza virus hemagglutinin in the metastable form required for fusion activity.
Journal of virology 1997;71(5):3719-25.
1997: Höfling K; Klenk H D; Herrler G
Inactivation of inhibitors by the receptor-destroying enzyme of influenza C virus.
The Journal of general virology 1997;78 ( Pt 3)():567-70.
1997: Hallenberger S; Moulard M; Sordel M; Klenk H D; Garten W
The role of eukaryotic subtilisin-like endoproteases for the activation of human immunodeficiency virus glycoproteins in natural host cells.
Journal of virology 1997;71(2):1036-45.
1996: Mühlberger E; Trommer S; Funke C; Volchkov V; Klenk H D; Becker S
Termini of all mRNA species of Marburg virus: sequence and secondary structure.
Virology 1996;223(2):376-80.
1996: Wagner R; Geyer H; Geyer R; Klenk H D
N-acetyl-beta-glucosaminidase accounts for differences in glycosylation of influenza virus hemagglutinin expressed in insect cells from a baculovirus vector.
Journal of virology 1996;70(6):4103-9.
1996: Feldmann H; Bugany H; Mahner F; Klenk H D; Drenckhahn D; Schnittler H J
Filovirus-induced endothelial leakage triggered by infected monocytes/macrophages.
Journal of virology 1996;70(4):2208-14.
1996: Höfling K; Brossmer R; Klenk H; Herrler G
Transfer of an esterase-resistant receptor analog to the surface of influenza C virions results in reduced infectivity due to aggregate formation.
Virology 1996;218(1):127-33.
1996: Wagner R; Liedtke S; Kretzschmar E; Geyer H; Geyer R; Klenk H D
Elongation of the N-glycans of fowl plague virus hemagglutinin expressed in Spodoptera frugiperda (Sf9) cells by coexpression of human beta 1,2-N-acetylglucosaminyltransferase I.
Glycobiology 1996;6(2):165-75.
1996: Kaverin N V; Ohuchi M; Ohuchi R; Klenk H D
Phenotypic mixing with recombinant haemagglutinin of high cleavability mediates multi-cycle replication of human influenza virus in cell culture.
The Journal of general virology 1996;77 ( Pt 1)():119-22.
1996: Feldmann H; Klenk H D
Marburg and Ebola viruses.
Advances in virus research 1996;47():1-52.
1996: Feldmann H; Slenczka W; Klenk H D
Emerging and reemerging of filoviruses.
Archives of virology. Supplementum 1996;11():77-100.
1995: Volchkov V E; Becker S; Volchkova V A; Ternovoj V A; Kotov A N; Netesov S V; Klenk H D
GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases.
Virology 1995;214(2):421-30.
1995: Pleschka S; Klenk H D; Herrler G
The catalytic triad of the influenza C virus glycoprotein HEF esterase: characterization by site-directed mutagenesis and functional analysis.
The Journal of general virology 1995;76 ( Pt 10)():2529-37.
1995: Itoh M; Hetterich P; Isecke R; Brossmer R; Klenk H D
Suppression of influenza virus infection by an N-thioacetylneuraminic acid acrylamide copolymer resistant to neuraminidase.
Virology 1995;212(2):340-7.
1995: Ohuchi M; Feldmann A; Ohuchi R; Klenk H D
Neuraminidase is essential for fowl plague virus hemagglutinin to show hemagglutinating activity.
Virology 1995;212(1):77-83.
1995: Hausmann J; Kretzschmar E; Garten W; Klenk H D
N1 neuraminidase of influenza virus A/FPV/Rostock/34 has haemadsorbing activity.
The Journal of general virology 1995;76 ( Pt 7)():1719-28.
1995: Zimmer G; Klenk H D; Herrler G
Identification of a 40-kDa cell surface sialoglycoprotein with the characteristics of a major influenza C virus receptor in a Madin-Darby canine kidney cell line.
The Journal of biological chemistry 1995;270(30):17815-22.
1995: Schäfer W; Stroh A; Berghöfer S; Seiler J; Vey M; Kruse M L; Kern H F; Klenk H D; Garten W
Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin.
The EMBO journal 1995;14(11):2424-35.
1995: Funke C; Becker S; Dartsch H; Klenk H D; Mühlberger E
Acylation of the Marburg virus glycoprotein.
Virology 1995;208(1):289-97.
1995: Creemers J W; Vey M; Schäfer W; Ayoubi T A; Roebroek A J; Klenk H D; Garten W; Van de Ven W J
Endoproteolytic cleavage of its propeptide is a prerequisite for efficient transport of furin out of the endoplasmic reticulum.
The Journal of biological chemistry 1995;270(6):2695-702.
1995: Becker S; Spiess M; Klenk H D
The asialoglycoprotein receptor is a potential liver-specific receptor for Marburg virus.
The Journal of general virology 1995;76 ( Pt 2)():393-9.
1995: Vey M; Schäfer W; Reis B; Ohuchi R; Britt W; Garten W; Klenk H D; Radsak K
Proteolytic processing of human cytomegalovirus glycoprotein B (gpUL55) is mediated by the human endoprotease furin.
Virology 1995;206(1):746-9.
1995: Kretzschmar E; Kuroda K; Klenk H D
Expression of the hemagglutinin protein of influenza virus. Analysis of protein modifications.
Methods in molecular biology (Clifton, N.J.) 1995;39():317-36.
1994: Vey M; Schäfer W; Berghöfer S; Klenk H D; Garten W
Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation.
The Journal of cell biology 1994;127(6 Pt 2):1829-42.
1994: Boycott R; Klenk H D; Ohuchi M
Cell tropism of influenza virus mediated by hemagglutinin activation at the stage of virus entry.
Virology 1994;203(2):313-9.
1994: Szepanski S; Veit M; Pleschka S; Klenk H D; Schmidt M F; Herrler G
Post-translational folding of the influenza C virus glycoprotein HEF: defective processing in cells expressing the cloned gene.
The Journal of general virology 1994;75 ( Pt 5)():1023-30.
1994: Kretzchmar E; Geyer R; Klenk H D
Baculovirus infection does not alter N-glycosylation in Spodoptera frugiperda cells.
Biological chemistry Hoppe-Seyler 1994;375(5):23-7.
1994: Ortmann D; Ohuchi M; Angliker H; Shaw E; Garten W; Klenk H D
Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2.
Journal of virology 1994;68(4):2772-6.
1994: Ohuchi M; Cramer A; Vey M; Ohuchi R; Garten W; Klenk H D
Rescue of vector-expressed fowl plague virus hemagglutinin in biologically active form by acidotropic agents and coexpressed M2 protein.
Journal of virology 1994;68(2):920-6.
1994: Klenk H D; Garten W
Host cell proteases controlling virus pathogenicity.
Trends in microbiology 1994;2(2):39-43.
1994: Garten W; Hallenberger S; Ortmann D; Schäfer W; Vey M; Angliker H; Shaw E; Klenk H D
Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones.
Biochimie 1994;76(3-4):217-25.
1993: Machytka D; Kharitonenkov I; Isecke R; Hetterich P; Brossmer R; Klein R A; Klenk H D; Egge H
Methyl alpha-glycoside of N-thioacetyl-D-neuraminic acid: a potential inhibitor of influenza A virus. A 1H NMR study.
FEBS letters 1993;334(1):117-20.
1993: Roberts P C; Garten W; Klenk H D
Role of conserved glycosylation sites in maturation and transport of influenza A virus hemagglutinin.
Journal of virology 1993;67(6):3048-60.
1993: Schnittler H J; Mahner F; Drenckhahn D; Klenk H D; Feldmann H
Replication of Marburg virus in human endothelial cells. A possible mechanism for the development of viral hemorrhagic disease.
The Journal of clinical investigation 1993;91(4):1301-9.
1993: Will C; Mühlberger E; Linder D; Slenczka W; Klenk H D; Feldmann H
Marburg virus gene 4 encodes the virion membrane protein, a type I transmembrane glycoprotein.
Journal of virology 1993;67(3):1203-10.
1993: Feldmann H; Klenk H D; Sanchez A
Molecular biology and evolution of filoviruses.
Archives of virology. Supplementum 1993;7():81-100.
1992: Hallenberger S; Bosch V; Angliker H; Shaw E; Klenk H D; Garten W
Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160.
Nature 1992;360(6402):358-61.
1992: Geyer H; Will C; Feldmann H; Klenk H D; Geyer R
Carbohydrate structure of Marburg virus glycoprotein.
Glycobiology 1992;2(4):299-312.
1992: Stieneke-Gröber A; Vey M; Angliker H; Shaw E; Thomas G; Roberts C; Klenk H D; Garten W
Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.
The EMBO journal 1992;11(7):2407-14.
1992: Feldmann H; Mühlberger E; Randolf A; Will C; Kiley M P; Sanchez A; Klenk H D
Marburg virus, a filovirus: messenger RNAs, gene order, and regulatory elements of the replication cycle.
Virus research 1992;24(1):1-19.
1992: Munk K; Pritzer E; Kretzschmar E; Gutte B; Garten W; Klenk H D
Carbohydrate masking of an antigenic epitope of influenza virus haemagglutinin independent of oligosaccharide size.
Glycobiology 1992;2(3):233-40.
1992: Szepanski S; Gross H J; Brossmer R; Klenk H D; Herrler G
A single point mutation of the influenza C virus glycoprotein (HEF) changes the viral receptor-binding activity.
Virology 1992;188(1):85-92.
1992: Vey M; Orlich M; Adler S; Klenk H D; Rott R; Garten W
Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R.
Virology 1992;188(1):408-13.
1992: Kretzschmar E; Veit M; Brunschön S; Kuroda K; Klenk H D
Secretion of fowl plague virus haemagglutinin from insect cells requires elimination of both hydrophobic domains.
The Journal of general virology 1992;73 ( Pt 4)():839-48.
1992: Mühlberger E; Sanchez A; Randolf A; Will C; Kiley M P; Klenk H D; Feldmann H
The nucleotide sequence of the L gene of Marburg virus, a filovirus: homologies with paramyxoviruses and rhabdoviruses.
Virology 1992;187(2):534-47.
1992: Garten W; Will C; Buckard K; Kuroda K; Ortmann D; Munk K; Scholtissek C; Schnittler H; Drenckhahn D; Klenk H D
Structure and assembly of hemagglutinin mutants of fowl plague virus with impaired surface transport.
Journal of virology 1992;66(3):1495-505.
1991: Ohuchi R; Ohuchi M; Garten W; Klenk H D
Human influenza virus hemagglutinin with high sensitivity to proteolytic activation.
Journal of virology 1991;65(7):3530-7.
1991: Klenk H D; Kuroda K; Kretzschmar E; Geyer R; Gröner A; Doerfler W
Processing of influenza virus hemagglutinin in insect cells.
Behring Institute Mitteilungen 1991;(89):27-34.
1991: Garten W; Vey M; Ohuchi R; Ohuchi M; Klenk H D
Modification of the cleavage activation of the influenza virus hemagglutinin by site-specific mutagenesis.
Behring Institute Mitteilungen 1991;(89):12-22.
1991: Veit M; Klenk H D; Kendal A; Rott R
The M2 protein of influenza A virus is acylated.
The Journal of general virology 1991;72 ( Pt 6)():1461-5.
1991: Feldmann H; Will C; Schikore M; Slenczka W; Klenk H D
Glycosylation and oligomerization of the spike protein of Marburg virus.
Virology 1991;182(1):353-6.
1991: Veit M; Kretzschmar E; Kuroda K; Garten W; Schmidt M F; Klenk H D; Rott R
Site-specific mutagenesis identifies three cysteine residues in the cytoplasmic tail as acylation sites of influenza virus hemagglutinin.
Journal of virology 1991;65(5):2491-500.
1991: Schultze B; Wahn K; Klenk H D; Herrler G
Isolated HE-protein from hemagglutinating encephalomyelitis virus and bovine coronavirus has receptor-destroying and receptor-binding activity.
Virology 1991;180(1):221-8.
1991: Kuroda K; Veit M; Klenk H D
Retarded processing of influenza virus hemagglutinin in insect cells.
Virology 1991;180(1):159-65.
1991: Herrler G; Klenk H D
Structure and function of the HEF glycoprotein of influenza C virus.
Advances in virus research 1991;40():213-34.
1991: Kendal A P; Klenk H D
Amantadine inhibits an early, M2 protein-dependent event in the replication cycle of avian influenza (H7) viruses.
Archives of virology 1991;119(3-4):265-73.
1990: Brücher K H; Garten W; Klenk H D; Shaw E; Radsak K
Inhibition of endoproteolytic cleavage of cytomegalovirus (HCMV) glycoprotein B by palmitoyl-peptidyl-chloromethyl ketone.
Virology 1990;178(2):617-20.
1990: Veit M; Herrler G; Schmidt M F; Rott R; Klenk H D
The hemagglutinating glycoproteins of influenza B and C viruses are acylated with different fatty acids.
Virology 1990;177(2):807-11.
1990: Schultze B; Gross H J; Brossmer R; Klenk H D; Herrler G
Hemagglutinating encephalomyelitis virus attaches to N-acetyl-9-O-acetylneuraminic acid-containing receptors on erythrocytes: comparison with bovine coronavirus and influenza C virus.
Virus research 1990;16(2):185-94.
1990: Pritzer E; Kuroda K; Garten W; Nagai Y; Klenk H D
A host range mutant of Newcastle disease virus with an altered cleavage site for proteolytic activation of the F protein.
Virus research 1990;15(3):237-42.
1990: Kuroda K; Geyer H; Geyer R; Doerfler W; Klenk H D
The oligosaccharides of influenza virus hemagglutinin expressed in insect cells by a baculovirus vector.
Virology 1990;174(2):418-29.
1990: Schultze B; Gross H J; Klenk H D; Brossmer R; Herrler G
Differential reactivity of bovine coronavirus (BCV) and influenza C virus with N-acetyl-9-O-acetylneuraminic acid (Neu5,9Ac2)-containing receptors.
Advances in experimental medicine and biology 1990;276():115-9.
1990: Schultze B; Hess G; Rott R; Klenk H D; Herrler G
Isolation and characterization of the acetylesterase of hemagglutinating encephalomyelitis virus (HEV).
Advances in experimental medicine and biology 1990;276():109-13.
1989: Garten W; Stieneke A; Shaw E; Wikstrom P; Klenk H D
Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones.
Virology 1989;172(1):25-31.
1989: Kuroda K; Gröner A; Frese K; Drenckhahn D; Hauser C; Rott R; Doerfler W; Klenk H D
Synthesis of biologically active influenza virus hemagglutinin in insect larvae.
Journal of virology 1989;63(4):1677-85.
1989: Ohuchi M; Orlich M; Ohuchi R; Simpson B E; Garten W; Klenk H D; Rott R
Mutations at the cleavage site of the hemagglutinin after the pathogenicity of influenza virus A/chick/Penn/83 (H5N2).
Virology 1989;168(2):274-80.
1988: Feldmann H; Kretzschmar E; Klingeborn B; Rott R; Klenk H D; Garten W
The structure of serotype H10 hemagglutinin of influenza A virus: comparison of an apathogenic avian and a mammalian strain pathogenic for mink.
Virology 1988;165(2):428-37.
1988: Herrler G; Dürkop I; Becht H; Klenk H D
The glycoprotein of influenza C virus is the haemagglutinin, esterase and fusion factor.
The Journal of general virology 1988;69 ( Pt 4)():839-46.
1988: Herrler G; Multhaup G; Beyreuther K; Klenk H D
Serine 71 of the glycoprotein HEF is located at the active site of the acetylesterase of influenza C virus.
Archives of virology 1988;102(3-4):269-74.
1988: Klenk H D; Rott R
The molecular biology of influenza virus pathogenicity.
Advances in virus research 1988;34():247-81.
1986: Schuy W; Will C; Kuroda K; Scholtissek C; Garten W; Klenk H D
Mutations blocking the transport of the influenza virus hemagglutinin between the rough endoplasmic reticulum and the Golgi apparatus.
The EMBO journal 1986;5(11):2831-6.
1985: Garten W; Kuroda K; Schuy W; Naruse H; Scholtissek C; Klenk H D
Haemagglutinin transport mutants.
Vaccine 1985;3(3 Suppl):227-9.
1984: Schuy W; Garten W; Linder D; Klenk H D
The carboxyterminus of the hemagglutinin-neuraminidase of Newcastle disease virus is exposed at the surface of the viral envelope.
Virus research 1984;1(5):415-26.

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