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Alexander Kleschevnikov

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Alexander M Kleschevnikov; Mehrdad Shamloo; Pavel V Belichenko; Mehrdad Faizi; Khin Htun; Lucia F Jacobs; William C. Mobley
Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists.
Alexander M Kleschevnikov; Michael T Maloney; Pavel V Belichenko; Jessica Gall; Lizzy George; Rachel Nosheny; Ahmad Salehi; William C. Mobley
Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome.
Alexander M Kleschevnikov; Ahmad Salehi; Pavel V Belichenko; C Wu
Discoveries in Down syndrome: moving basic science to clinical care.

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2012: Alexander M Kleschevnikov; Mehrdad Shamloo; Pavel V Belichenko; Mehrdad Faizi; Khin Htun; Lucia F Jacobs; William C. Mobley
Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(27):9217-27.
2012: Alexander M Kleschevnikov; Michael T Maloney; Pavel V Belichenko; Jessica Gall; Lizzy George; Rachel Nosheny; Ahmad Salehi; William C. Mobley
Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome.
Neurobiology of disease 2012;45(2):683-91.
2012: Alexander M Kleschevnikov; Ahmad Salehi; Pavel V Belichenko; C Wu
Discoveries in Down syndrome: moving basic science to clinical care.
Progress in brain research 2012;197():199-221.
2012: Li Zhang; Pavel V Belichenko; Steven J Clapcote; Dawei Fu; Alexander M Kleschevnikov; Ping Liang; Chunhong Liu; William C Mobley; Annie Pao; Y Eugene Yu
Genetic analysis of Down syndrome facilitated by mouse chromosome engineering.
Bioengineered bugs 2012;3(1):8-12.
2011: Mehrdad Faizi; Alexander M Kleschevnikov; William C. Mobley; Matthew Priestley; Nay Saw; Patrick L Bader; Pavel V Belichenko; Angelo Encarnacion; Richard W Tsien; Christine Tun; Mehrdad Shamloo
Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer.
Neurobiology of disease 2011;43(2):397-413.
2011: Victor I Popov; Alexander M Kleschevnikov; Oleg A Klimenko; Michael G Stewart; Pavel V Belichenko
Three-dimensional synaptic ultrastructure in the dentate gyrus and hippocampal area CA3 in the Ts65Dn mouse model of Down syndrome.
The Journal of comparative neurology 2011;519(7):1338-54.
2009: Ahmad Salehi; Mehrdad Faizi; D Colas; Janice S Valletta; J Laguna; R Takimoto-Kimura; Alexander M Kleschevnikov; S L Wagner; P Aisen; Mehrdad Shamloo; William C. Mobley
Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome.
Science translational medicine 2009;1(7):7ra17.
2009: Nadia P Belichenko; Pavel V Belichenko; Alexander M Kleschevnikov; Ahmad Salehi; Roger H Reeves; William C. Mobley
The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(18):5938-48.
2009: Pavel V Belichenko; Alexander M Kleschevnikov; Eliezer Masliah; Chengbiao Wu; Ryoko Takimoto-Kimura; Ahmad Salehi; William C. Mobley
Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome.
The Journal of comparative neurology 2009;512(4):453-66.
2007: Pavel V Belichenko; Alexander M Kleschevnikov; Ahmad Salehi; Charles J Epstein; William C. Mobley
Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships.
The Journal of comparative neurology 2007;504(4):329-45.
2006: Ahmad Salehi; Jean-Dominique Delcroix; Pavel V Belichenko; Ke Zhan; Chengbiao Wu; Janice S Valletta; Ryoko Takimoto-Kimura; Alexander M Kleschevnikov; Kumar Sambamurti; Peter P Chung; Weiming Xia; Angela Villar; William A Campbell; Laura Shapiro Kulnane; Ralph A. Nixon; Bruce Lamb; Charles J Epstein; Gorazd B Stokin; Lawrence S B Goldstein; William C. Mobley
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.
Neuron 2006;51(1):29-42.
2004: Pavel V Belichenko; Eliezer Masliah; Alexander M Kleschevnikov; Angela J Villar; Charles J Epstein; Ahmad Salehi; William C. Mobley
Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome.
The Journal of comparative neurology 2004;480(3):281-98.
2004: Alexander M Kleschevnikov; Pavel V Belichenko; Angela J Villar; Charles J Epstein; Robert C Malenka; William C. Mobley
Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(37):8153-60.
2003: Alexander M Kleschevnikov; Aryeh Routtenberg
Long-term potentiation recruits a trisynaptic excitatory associative network within the mouse dentate gyrus.
The European journal of neuroscience 2003;17(12):2690-702.
2001: Alexander M Kleschevnikov; Aryeh Routtenberg
PKC activation rescues LTP from NMDA receptor blockade.
Hippocampus 2001;11(2):168-75.