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Lars Klimaschewski

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Maria Auer; Mohammed Barham; Xavier Navarro; Wolfram F Neiss; Esther Udina; Ilary Allodi; Lars Klimaschewski
C3 exoenzyme lacks effects on peripheral axon regeneration in vivo.
Lisa Fellner; Regina Irschick; Lars Klimaschewski; Werner Poewe; Markus Reindl; Kathrin Schanda; Gregor Wenning; Nadia Stefanova
Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia.
Regina Irschick; Georg Karp; Maria Auer; Peter Claus; Barbara Hausott; Tobias Trost; Lars Klimaschewski
Sorting of the FGF receptor 1 in a human glioma cell line.

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All Publications

2013: Maria Auer; Mohammed Barham; Xavier Navarro; Wolfram F Neiss; Esther Udina; Ilary Allodi; Lars Klimaschewski
C3 exoenzyme lacks effects on peripheral axon regeneration in vivo.
Journal of the peripheral nervous system : JPNS 2013;18(1):30-6.
2013: Lisa Fellner; Regina Irschick; Lars Klimaschewski; Werner Poewe; Markus Reindl; Kathrin Schanda; Gregor Wenning; Nadia Stefanova
Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia.
Glia 2013;61(3):349-60.
2013: Regina Irschick; Georg Karp; Maria Auer; Peter Claus; Barbara Hausott; Tobias Trost; Lars Klimaschewski
Sorting of the FGF receptor 1 in a human glioma cell line.
Histochemistry and cell biology 2013;139(1):135-48.
2012: Philipp Lirk; Markus F Stevens; Suzuko Suzuki; Stephan Blumenthal; Magdalena Flatz; Ingrid Haller; Barbara Hausott; Lars Klimaschewski; Peter Gerner
In Zucker diabetic fatty rats, subclinical diabetic neuropathy increases in vivo lidocaine block duration but not in vitro neurotoxicity.
Regional anesthesia and pain medicine 2012;37(6):601-6.
2012: Barbara Hausott; Maria Auer; Beate Brand-Saberi; Fangping Dai; Benedikt Nimmervoll; Gerald Obermair; Bettina Schlick; Christoph Schwarzer; Natalie Vallant; Lars Klimaschewski
Sprouty2 and -4 regulate axon outgrowth by hippocampal neurons.
Hippocampus 2012;22(3):434-41.
2012: Niko Hensel; Lars Klimaschewski; Andreas Ratzka; Hella Brinkmann; Claudia Grothe; Peter Claus
Analysis of the fibroblast growth factor system reveals alterations in a mouse model of spinal muscular atrophy.
PloS one 2012;7(2):e31202.
2011: Barbara Hausott; M Auer; I Haller; Susanne Perkhofer; A Rietzler; N Vallant; Lars Klimaschewski
Inhibition of fibroblast growth factor receptor 1 endocytosis promotes axonal branching of adult sensory neurons.
Neuroscience 2011;188():13-22.
2011: M Seitz; Maria Grosheva; Emmanouil Skouras; S K Angelova; J Ankerne; J Jungnickel; C Grothe; Lars Klimaschewski; C U Hübbers; S A Dunlop; Doychin Angelov
Poor functional recovery and muscle polyinnervation after facial nerve injury in fibroblast growth factor-2-/- mice can be improved by manual stimulation of denervated vibrissal muscles.
Neuroscience 2011;182():241-7.
2010: L Lang; Shota Ingorokva; Barbara Hausott; N Vallant; S Schmidt; Christoph Schwarzer; Lars Klimaschewski
Selective up-regulation of the vasodilator peptide apelin after dorsal root but not after spinal nerve injury.
Neuroscience 2010;170(3):954-60.
2010: Francesco Boato; Sven Hendrix; Stefanie C Huelsenbeck; Fred Hofmann; Gisela Grosse; Susann Djalali; Lars Klimaschewski; Maria Auer; Ingo Just; Gudrun Ahnert-Hilger; Markus Höltje
C3 peptide enhances recovery from spinal cord injury by improved regenerative growth of descending fiber tracts.
Journal of cell science 2010;123(Pt 10):1652-62.
2009: Barbara Hausott; Isil Kurnaz; Srecko Gajovic; Lars Klimaschewski
Signaling by neuronal tyrosine kinase receptors: relevance for development and regeneration.
Anatomical record (Hoboken, N.J. : 2007) 2009;292(12):1976-85.
2009: Ozlem Demir; Sheila Singh; Lars Klimaschewski; Isil Aksan Kurnaz
From birth till death: neurogenesis, cell cycle, and neurodegeneration.
Anatomical record (Hoboken, N.J. : 2007) 2009;292(12):1953-61.
2009: Barbara Hausott; Natalie Vallant; Maria Auer; Lin Yang; Fangping Dai; Beate Brand-Saberi; Lars Klimaschewski
Sprouty2 down-regulation promotes axon growth by adult sensory neurons.
Molecular and cellular neurosciences 2009;42(4):328-40.
2008: Christina Doverhag; Matthias Keller; Anna Karlsson; Maj Hedtjarn; Ulf Nilsson; Edith Kapeller; Gergely Sárközy; Lars Klimaschewski; Christian Humpel; Henrik Hagberg; Georg Simbruner; Pierre Gressens; Karin Savman
Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice.
Neurobiology of disease 2008;31(1):133-44.
2008: Barbara Hausott; Bettina Schlick; N Vallant; R Dorn; Lars Klimaschewski
Promotion of neurite outgrowth by fibroblast growth factor receptor 1 overexpression and lysosomal inhibition of receptor degradation in pheochromocytoma cells and adult sensory neurons.
Neuroscience 2008;153(2):461-73.
2008: Philipp Lirk; Ingrid Haller; Hans Peter Colvin; Leopold Lang; Bettina Thauerer; Lars Klimaschewski; Peter Gerner
In vitro, inhibition of mitogen-activated protein kinase pathways protects against bupivacaine- and ropivacaine-induced neurotoxicity.
Anesthesia and analgesia 2008;106(5):1456-64, table of contents.
2007: Rüdiger Schweigreiter; Taras Stasyk; Igea Contarini; Silke Frauscher; Thomas Oertle; Lars Klimaschewski; Lukas A Huber; Christine E Bandtlow
Phosphorylation-regulated cleavage of the reticulon protein Nogo-B by caspase-7 at a noncanonical recognition site.
Proteomics 2007;7(24):4457-67.
2007: Benjamin Dieplinger; Natalia Schiefermeier; Michaela Juchum-Pasquazzo; Ronald Gstir; Lukas A Huber; Lars Klimaschewski; Ilja Vietor
The transcriptional corepressor TPA-inducible sequence 7 regulates adult axon growth through cellular retinoic acid binding protein II expression.
The European journal of neuroscience 2007;26(12):3358-67.
2007: Philipp Lirk; Ingrid Haller; Hans Peter Colvin; Silke Frauscher; Lukas Kirchmair; Peter Gerner; Lars Klimaschewski
In vitro, lidocaine-induced axonal injury is prevented by peripheral inhibition of the p38 mitogen-activated protein kinase, but not by inhibiting caspase activity.
Anesthesia and analgesia 2007;105(6):1657-64, table of contents.
2007: Ingrid Haller; Philipp Lirk; Christian Keller; Ging Kuo Wang; Peter Gerner; Lars Klimaschewski
Differential neurotoxicity of tricyclic antidepressants and novel derivatives in vitro in a dorsal root ganglion cell culture model.
European journal of anaesthesiology 2007;24(8):702-8.
2006: Ingrid Haller; Barbara Hausott; Bettina Thauerer; Christian Keller; Lars Klimaschewski; Peter Gerner; Philipp Lirk
Neurotoxicity of lidocaine involves specific activation of the p38 mitogen-activated protein kinase, but not extracellular signal-regulated or c-jun N-terminal kinases, and is mediated by arachidonic acid metabolites.
Anesthesiology 2006;105(5):1024-33.
2006: Victor Suarez; Orlando Guntinas-Lichius; Michael Streppel; Shota Ingorokva; Maria Grosheva; Wolfram F Neiss; Doychin Angelov; Lars Klimaschewski
The axotomy-induced neuropeptides galanin and pituitary adenylate cyclase-activating peptide promote axonal sprouting of primary afferent and cranial motor neurones.
The European journal of neuroscience 2006;24(6):1555-64.
2006: Philipp Lirk; Ingrid Haller; Robert R Myers; Lars Klimaschewski; Yi-Chuan Kau; Yu-Chun Hung; Peter Gerner
Mitigation of direct neurotoxic effects of lidocaine and amitriptyline by inhibition of p38 mitogen-activated protein kinase in vitro and in vivo.
Anesthesiology 2006;104(6):1266-73.
2006: Philipp Lirk; Ingrid Haller; Barbara Hausott; Shota Ingorokva; Martina Deibl; Peter Gerner; Lars Klimaschewski
The neurotoxic effects of amitriptyline are mediated by apoptosis and are effectively blocked by inhibition of caspase activity.
Anesthesia and analgesia 2006;102(6):1728-33.
2006: Lars Klimaschewski; Barbara Hausott; Shota Ingorokva; Kristian Pfaller
Constitutively expressed catalytic proteasomal subunits are up-regulated during neuronal differentiation and required for axon initiation, elongation and maintenance.
Journal of neurochemistry 2006;96(6):1708-17.
2005: Pujan Kavakebi; Barbara Hausott; Andre Tomasino; Shota Ingorokva; Lars Klimaschewski
The N-end rule ubiquitin-conjugating enzyme, HR6B, is up-regulated by nerve growth factor and required for neurite outgrowth.
Molecular and cellular neurosciences 2005;29(4):559-68.
2005: Andre Tomasino; Lars Klimaschewski
Tissue distribution of the "N-end rule" ubiquitin-conjugating enzyme, HR6, in the rat.
Histochemistry and cell biology 2005;123(4-5):483-9.
2005: Josef Troger; Alfred Doblinger; Johannes Leierer; Andrea Laslop; Eduard Schmid; Barbara Teuchner; Markus Opatril; Wolfgang Philipp; Lars Klimaschewski; Kristian Pfaller; Wolfgang Göttinger; Reiner Fischer-Colbrie
Secretoneurin in the peripheral ocular innervation.
Investigative ophthalmology & visual science 2005;46(2):647-54.
2004: Susanne Eder; Johannes Leierer; Lars Klimaschewski; Alexander Wilhelm; Walter Volknandt; Andrea Laslop; Reiner Fischer-Colbrie
Secretion and molecular forms of NESP55, a novel genomically imprinted neuroendocrine-specific protein from AtT-20 cells.
Neuro-Signals 2004;13(6):298-307.
2004: Philipp Lirk; Stefano Longato; Josef Rieder; Lars Klimaschewski
Cisatracurium, but not mivacurium, inhibits survival and axonal growth of neonatal and adult rat peripheral neurons in vitro.
Neuroscience letters 2004;365(2):153-5.
2004: Lars Klimaschewski; Werner Nindl; J Feurle; Pujan Kavakebi; Herwig Kostron
Basic fibroblast growth factor isoforms promote axonal elongation and branching of adult sensory neurons in vitro.
Neuroscience 2004;126(2):347-53.
2004: Werner Nindl; Pujan Kavakebi; Peter Claus; C Grothe; Kristian Pfaller; Lars Klimaschewski
Expression of basic fibroblast growth factor isoforms in postmitotic sympathetic neurons: synthesis, intracellular localization and involvement in karyokinesis.
Neuroscience 2004;124(3):561-72.
2003: Nadia Stefanova; Kathrin Schanda; Lars Klimaschewski; Werner Poewe; Gregor Wenning; Markus Reindl
Tumor necrosis factor-alpha-induced cell death in U373 cells overexpressing alpha-synuclein.
Journal of neuroscience research 2003;73(3):334-40.
2003: Lars Klimaschewski
Ubiquitin-dependent proteolysis in neurons.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2003;18():29-33.
2002: Nadia Stefanova; M Emgård; Lars Klimaschewski; Gregor Wenning; Markus Reindl
Ultrastructure of alpha-synuclein-positive aggregations in U373 astrocytoma and rat primary glial cells.
Neuroscience letters 2002;323(1):37-40.
2002: Lars Klimaschewski; Werner Nindl; Michael Pimpl; Peter Waltinger; Kristian Pfaller
Biolistic transfection and morphological analysis of cultured sympathetic neurons.
Journal of neuroscience methods 2002;113(1):63-71.
2002: Mariusz Majewski; Jerzy Kaleczyc; Krzysztof Wasowicz; Agnieszka Bossowska; Slawomir Gonkowski; Lars Klimaschewski
Characterization of afferent and efferent galanin-containing nerve fibres in the porcine ovary.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 2002;40(3):261-8.
2001: Lars Klimaschewski; Nicholas Obermüller; Ralph Witzgall
Regulation of clusterin expression following spinal cord injury.
Cell and tissue research 2001;306(2):209-16.
2001: Nadia Stefanova; Lars Klimaschewski; Werner Poewe; Gregor Wenning; Markus Reindl
Glial cell death induced by overexpression of alpha-synuclein.
Journal of neuroscience research 2001;65(5):432-8.
2001: Lars Klimaschewski
Increased innervation of rat preganglionic sympathetic neurons by substance P containing nerve fibers in response to spinal cord injury.
Neuroscience letters 2001;307(2):73-6.
1999: Lars Klimaschewski; C Meisinger; C Grothe
Localization and regulation of basic fibroblast growth factor (FGF-2) and FGF receptor-1 in rat superior cervical ganglion after axotomy.
Journal of neurobiology 1999;38(4):499-506.
1998: A Eschelbach; A Hunziker; Lars Klimaschewski
Differential display PCR reveals induction of immediate early genes by vasoactive intestinal peptide in PC12 cells.
Annals of the New York Academy of Sciences 1998;865():181-8.
1997: Lars Klimaschewski
Regulation of galanin in rat sympathetic neurons in vitro.
Neuroscience letters 1997;234(2-3):87-90.
1997: S Kroesen; S Lang; Reiner Fischer-Colbrie; Lars Klimaschewski
Plasticity of neuropeptide Y in the rat superior cervical ganglion in response to nerve lesion.
Neuroscience 1997;78(1):251-8.
1996: Lars Klimaschewski; C Hauser; C Heym
PACAP immunoreactivity in the rat superior cervical ganglion in comparison to VIP.
Neuroreport 1996;7(15-17):2797-801.
1996: Lars Klimaschewski; Wolfgang Kummer; C Heym
Localization, regulation and functions of neurotransmitters and neuromodulators in cervical sympathetic ganglia.
Microscopy research and technique 1996;35(1):44-68.
1996: Lars Klimaschewski; Nicholas Obermüller; Mariusz Majewski; Sebastian Bachmann; C Heym
Increased expression of nitric oxide synthase in a subpopulation of rat sympathetic neurons after axotomy - correlation with vasoactive intestinal peptide.
Cell and tissue research 1996;285(3):419-25.
1996: Lars Klimaschewski; I Grohmann; C Heym
Target-dependent plasticity of galanin and vasoactive intestinal peptide in the rat superior cervical ganglion after nerve lesion and re-innervation.
Neuroscience 1996;72(1):265-72.
1996: M Colombo-Benkmann; Lars Klimaschewski; C Heym
Immunohistochemical heterogeneity of nerve cells in the human adrenal gland with special reference to substance P.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(4):369-75.
1995: C Heym; B Braun; Y Shuyi; Lars Klimaschewski; M Colombo-Benkmann
Immunohistochemical correlation of human adrenal nerve fibres and thoracic dorsal root neurons with special reference to substance P.
Histochemistry and cell biology 1995;104(3):233-43.
1995: Lars Klimaschewski; Klaus Unsicker; C Heym
Vasoactive intestinal peptide but not galanin promotes survival of neonatal rat sympathetic neurons and neurite outgrowth of PC12 cells.
Neuroscience letters 1995;195(2):133-6.
1995: Lars Klimaschewski; K Benndorf; R Kirchmair; R Fischer-Colbrie; C Heym
Secretoneurin-immunoreactivity in nerve terminals apposing identified preganglionic sympathetic neurons in the rat: colocalization with substance P and enkephalin.
Journal of chemical neuroanatomy 1995;9(1):55-63.
1995: C Heym; B Braun; Lars Klimaschewski; Wolfgang Kummer
Chemical codes of sensory neurons innervating the guinea-pig adrenal gland.
Cell and tissue research 1995;279(1):169-81.
1994: Lars Klimaschewski; Stefan Reuss; Rainer Spessert; C Lobron; Andrea Wevers; C Heym; Alfred Maelicke; H Schröder
Expression of nicotinic acetylcholine receptors in the rat superior cervical ganglion on mRNA and protein level.
Brain research. Molecular brain research 1994;27(1):167-73.
1994: C Heym; Lars Klimaschewski; N Borghini; R Fischer-Colbrie
Immunohistochemistry of small intensely fluorescent (SIF) cells and of SIF cell-associated nerve fibers in the rat superior cervical ganglion.
Microscopy research and technique 1994;29(2):143-50.
1994: Lars Klimaschewski; T D Tran; R Nobiling; C Heym
Plasticity of postganglionic sympathetic neurons in the rat superior cervical ganglion after axotomy.
Microscopy research and technique 1994;29(2):120-30.
1993: C Heym; B Common; S Yin; Lars Klimaschewski; J Y Couraud; Sebastian Bachmann
Neurochemistry, connectivity and plasticity of small intensely fluorescent (SIF) cells in the rat superior cervical ganglion.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 1993;175(4):309-19.
1993: C Heym; B Common; Lars Klimaschewski; U Preissler; Wolfgang Kummer
Immunohistochemical evidence from co-localization and denervation studies for four types of substance P-containing nervous structures in the rat superior cervical ganglion.
Anatomy and embryology 1993;187(5):485-92.
1992: Lars Klimaschewski; Wolfgang Kummer; B Mayer; J Y Couraud; U Preissler; B Philippin; C Heym
Nitric oxide synthase in cardiac nerve fibers and neurons of rat and guinea pig heart.
Circulation research 1992;71(6):1533-7.