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Sharyn Baker

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Eric I Zimmerman; AA Gibson; Shuiying Hu; Lie Li; Shelley J Orwick; Justin L Roberts; Alex Sparreboom; Sharyn D Baker
Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.
C D Drenberg; Sharyn D Baker; Alex Sparreboom
Integrating clinical pharmacology concepts in individualized therapy with tyrosine kinase inhibitors.
Fariba Navid; John C Panetta; Wilburn E Reddick; Sheri L Spunt; Clinton F Stewart; David Turner; Jianrong Wu; Sharyn D Baker; Catherine A Billups; Andrew M Davidoff; Demba Fofana; Wayne L Furman; Shuiying Hu; Wing Leung; M Beth McCarville; Lisa M McGregor; Victor M Santana
Phase I and clinical pharmacology study of bevacizumab, sorafenib, and low-dose cyclophosphamide in children and young adults with refractory/recurrent solid tumors.

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All Publications

2013: Eric I Zimmerman; AA Gibson; Shuiying Hu; Lie Li; Shelley J Orwick; Justin L Roberts; Alex Sparreboom; Sharyn D Baker
Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(6):1458-66.
2013: C D Drenberg; Sharyn D Baker; Alex Sparreboom
Integrating clinical pharmacology concepts in individualized therapy with tyrosine kinase inhibitors.
Clinical pharmacology and therapeutics 2013;93(3):215-9.
2013: Fariba Navid; John C Panetta; Wilburn E Reddick; Sheri L Spunt; Clinton F Stewart; David Turner; Jianrong Wu; Sharyn D Baker; Catherine A Billups; Andrew M Davidoff; Demba Fofana; Wayne L Furman; Shuiying Hu; Wing Leung; M Beth McCarville; Lisa M McGregor; Victor M Santana
Phase I and clinical pharmacology study of bevacizumab, sorafenib, and low-dose cyclophosphamide in children and young adults with refractory/recurrent solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(1):236-46.
2012: Eric I Zimmerman; Amarjit S Chaudhry; David Finkelstein; Alice Gibson; Hiroto Inaba; Lie Li; Justin L Roberts; Jeffrey E Rubnitz; Erin G Schuetz; Sharyn D Baker
Ontogeny and sorafenib metabolism.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(20):5788-95.
2012: Anne-Joy M de Graan; Guoqing Du; Laure Elens; Lena E Friberg; Alice A Gibson; Bruno Hagenbuch; Shuiying Hu; Cynthia S Lancaster; Walter J Loos; Ron H J Mathijssen; Torben S Mikkelsen; Amanda Obaidat; Sharyn D Baker; Gitte H Bruun; Thomas J Corydon; Peter de Bruijn; Ron H N van Schaik; Aisha L Walker; Alex Sparreboom
Influence of polymorphic OATP1B-type carriers on the disposition of docetaxel.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(16):4433-40.
2012: Anne-Joy M de Graan; Lena E Friberg; Walter J Loos; Jessica M van der Bol; Bronno van der Holt; Leni van Doorn; Jaap Verweij; Erik A C Wiemer; Sharyn D Baker; Ron H J Mathijssen
Influence of smoking on the pharmacokinetics and toxicity profiles of taxane therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(16):4425-32.
2012: Chaoxin Hu; Shuiying Hu; Cynthia S Lancaster; Jeffrey E Rubnitz; Sharyn D Baker; Zhaoyuan Chen; Zhili Zuo; Alex Sparreboom
Inhibition of OCTN2-mediated transport of carnitine by etoposide.
Molecular cancer therapeutics 2012;11(4):921-9.
2011: Colin D Weekes; Sharyn D Baker; Ross C Donehower; Manuel Hidalgo; Antonio Jimeno; Daniel Laheru; KATHLEEN MURPHY; Sujatha Nallapareddy; Alexis Norris-Kirby; MICHELLE RUDEK-RENAUT; Wells A Messersmith
Thymidylate synthase (TYMS) enhancer region genotype-directed phase II trial of oral capecitabine for 2nd line treatment of advanced pancreatic cancer.
Investigational new drugs 2011;29(5):1057-65.
2011: Hiroto Inaba; Lie Li; Gerard P Mascara; Mihaela Onciu; Stanley Pounds; Ching-Hon Pui; Raul C Ribeiro; Jeffrey E Rubnitz; Sheila A Shurtleff; Dario Campana; Robbin Christensen; Elaine Coustan-Smith; Brian D Furmanski; Kenneth M Heym; Sharyn D Baker
Phase I pharmacokinetic and pharmacodynamic study of the multikinase inhibitor sorafenib in combination with clofarabine and cytarabine in pediatric relapsed/refractory leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(24):3293-300.
2011: Shuiying Hu; Hiroto Inaba; Hongmei Niu; Shelley Orwick; John C Panetta; Stanley Pounds; Jerold E Rehg; Charles Rose; Jeffrey E Rubnitz; Shengping Yang; Christopher Calabrese; Dario Campana; Yiping Fan; Sharyn D Baker
Activity of the multikinase inhibitor sorafenib in combination with cytarabine in acute myeloid leukemia.
Journal of the National Cancer Institute 2011;103(11):893-905.
2011: Ryan Franke; C S Lancaster; C J Peer; A A Gibson; A M Kosloske; S J Orwick; Ron H J Mathijssen; W D Figg; Sharyn D Baker; Alex Sparreboom
Effect of ABCC2 (MRP2) transport function on erythromycin metabolism.
Clinical pharmacology and therapeutics 2011;89(5):693-701.
2011: Roisin M Connolly; MICHELLE RUDEK-RENAUT; Elizabeth Garrett-Mayer; Stacie C Jeter; Michele G Donehower; Laurie A Wright; Ming Zhao; John H Fetting; Leisha A Emens; Vered Stearns; Nancy E Davidson; Sharyn D Baker; Antonio C Wolff
Docetaxel metabolism is not altered by imatinib: findings from an early phase study in metastatic breast cancer.
Breast cancer research and treatment 2011;127(1):153-62.
2011: Charles G Mullighan; Jinghui Zhang; Lawryn H Kasper; Stephanie Lerach; Debbie Payne-Turner; Letha A Phillips; Sue L Heatley; Linda Holmfeldt; J Racquel Collins-Underwood; Jing Ma; Kenneth H Buetow; Ching-Hon Pui; Sharyn D Baker; Paul K Brindle; James R Downing
CREBBP mutations in relapsed acute lymphoblastic leukaemia.
Nature 2011;471(7337):235-9.
2011: Jatinder K Lamba; Kristine R Crews; Stanley B Pounds; Xueyuan Cao; Varsha Gandhi; William Plunkett; Bassem I Razzouk; Vishal Lamba; Sharyn D Baker; Susana C Raimondi; Dario Campana; Ching-Hon Pui; James R Downing; Jeffrey E Rubnitz; Raul C Ribeiro
Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes.
Pharmacogenomics 2011;12(3):327-39.
2011: Nielka P H van Erp; Sharyn D Baker; Anthe S Zandvliet; Bart A Ploeger; Margaret den Hollander; Zhaoyuan Chen; Jan den Hartigh; Jacqueline M C König-Quartel; Henk-Jan Guchelaar; Hans Gelderblom
Marginal increase of sunitinib exposure by grapefruit juice.
Cancer chemotherapy and pharmacology 2011;67(3):695-703.
2011: B Douglas Smith; Richard J Jones; Eunpi Cho; Jeanne Kowalski; Judith E Karp; Steven D Gore; Milada Vala; Brooke Meade; Sharyn D Baker; Ming Zhao; Steven Piantadosi; Zhe Zhang; Gideon Blumenthal; Erica D Warlick; Robert A Brodsky; Anthony Murgo; MICHELLE RUDEK-RENAUT; William Matsui
Differentiation therapy in poor risk myeloid malignancies: Results of a dose finding study of the combination bryostatin-1 and GM-CSF.
Leukemia research 2011;35(1):87-94.
2010: Lie Li; Ming Zhao; Fariba Navid; Keith William Pratz; B Douglas Smith; MICHELLE RUDEK-RENAUT; Sharyn D Baker
Quantitation of sorafenib and its active metabolite sorafenib N-oxide in human plasma by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(29):3033-8.
2010: Ryan M Franke; Michael A Carducci; MICHELLE RUDEK-RENAUT; Sharyn D Baker; Alex Sparreboom
Castration-dependent pharmacokinetics of docetaxel in patients with prostate cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(30):4562-7.
2010: Keith William Pratz; E Cho; Mark Levis; Judith E Karp; Steven D Gore; A MICHAEL MCDEVITT; A Stine; Ming Zhao; Sharyn D Baker; Michael A Carducci; John J Wright; MICHELLE RUDEK-RENAUT; B Douglas Smith
A pharmacodynamic study of sorafenib in patients with relapsed and refractory acute leukemias.
Leukemia 2010;24(8):1437-44.
2009: Emmanuel S Antonarakis; Elisabeth Iljas Heath; JANET WALCZAK; William G Nelson; Helen Fedor; Angelo M DeMarzo; Marianna L Zahurak; Steven Piantadosi; Andrew J Dannenberg; Robin T Gurganus; Sharyn D Baker; Howard L Parnes; Theodore L DeWeese; Alan W Partin; Michael A Carducci
Phase II, randomized, placebo-controlled trial of neoadjuvant celecoxib in men with clinically localized prostate cancer: evaluation of drug-specific biomarkers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(30):4986-93.
2009: Jianqing Lin; Jill Gilbert; MICHELLE RUDEK-RENAUT; James Zwiebel; Steven D Gore; Anchalee Jiemjit; Ming Zhao; Sharyn D Baker; Richard F Ambinder; James G Herman; Ross C Donehower; Michael A Carducci
A phase I dose-finding study of 5-azacytidine in combination with sodium phenylbutyrate in patients with refractory solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6241-9.
2009: Shuiying Hu; Zhaoyuan Chen; Ryan Franke; Shelley Orwick; Ming Zhao; MICHELLE RUDEK-RENAUT; Alex Sparreboom; Sharyn D Baker
Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6062-9.
2008: Antonio Jimeno; Jing Li; Wells A Messersmith; Daniel Laheru; MICHELLE RUDEK-RENAUT; Manoj Maniar; Manuel Hidalgo; Sharyn D Baker; Ross C Donehower
Phase I study of ON 01910.Na, a novel modulator of the Polo-like kinase 1 pathway, in adult patients with solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(34):5504-10.
2008: Patton Minkin; Ming Zhao; Zhaoyuan Chen; Jan Ouwerkerk; Hans Gelderblom; Sharyn D Baker
Quantification of sunitinib in human plasma by high-performance liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;874(1-2):84-8.
2008: Antonio Jimeno; MICHELLE RUDEK-RENAUT; Peter Kulesza; Wen W Ma; Jenna Wheelhouse; Anna Howard; Yasmin Khan; Ming Zhao; Heather A Jacene; Wells A Messersmith; Daniel Laheru; Ross C Donehower; Elizabeth Garrett-Mayer; Sharyn D Baker; Manuel Hidalgo
Pharmacodynamic-guided modified continuous reassessment method-based, dose-finding study of rapamycin in adult patients with solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(25):4172-9.
2008: Dana Elizabeth Rathkopf; Michael A Carducci; Michael J Morris; Susan F Slovin; Mario A Eisenberger; Roberto Pili; Samuel R Denmeade; Moshe Kelsen; Tracy Curley; Melinda Halter; Connie Collins; Martin Fleisher; Glenn Heller; Sharyn D Baker; Howard I Scher
Phase II trial of docetaxel with rapid androgen cycling for progressive noncastrate prostate cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(18):2959-65.
2008: Nicola F Smith; Sharyn D Baker; Frank J Gonzalez; J W Harris; William D Figg; Alex Sparreboom
Modulation of erlotinib pharmacokinetics in mice by a novel cytochrome P450 3A4 inhibitor, BAS 100.
British journal of cancer 2008;98(10):1630-2.
2008: Shuiying Hu; Ryan Franke; Kelly K Filipski; Chaoxin Hu; Shelley J Orwick; Ernst A de Bruijn; Herman Burger; Sharyn D Baker; Alex Sparreboom
Interaction of imatinib with human organic ion carriers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(10):3141-8.
2008: Shuiying Hu; Hongmei Niu; Patton Minkin; Shelley Orwick; Akira Shimada; Hiroto Inaba; Gary V H Dahl; Jeffrey Rubnitz; Sharyn D Baker
Comparison of antitumor effects of multitargeted tyrosine kinase inhibitors in acute myelogenous leukemia.
Molecular cancer therapeutics 2008;7(5):1110-20.
2008: Jing Li; Michael B Jameson; Bruce C Baguley; Roberto Pili; Sharyn D Baker
Population pharmacokinetic-pharmacodynamic model of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid in cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(7):2102-10.
2008: Vanesa Gregorc; Manuel Hidalgo; Anna Spreafico; George Cusatis; Vienna Ludovini; Roxann G Ingersoll; S Marsh; S M Steinberg; M G Viganò; D Ghio; Eugenio Villa; Alex Sparreboom; Sharyn D Baker
Germline polymorphisms in EGFR and survival in patients with lung cancer receiving gefitinib.
Clinical pharmacology and therapeutics 2008;83(3):477-84.
2008: Antonio Jimeno; MICHELLE RUDEK-RENAUT; W. PURCELL; Daniel Laheru; Wells A Messersmith; Janet Dancey; Michael A Carducci; Sharyn D Baker; Manuel Hidalgo; Ross C Donehower
Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors.
Cancer chemotherapy and pharmacology 2008;61(3):423-33.
2008: Antonio Jimeno; Wells A Messersmith; Carlton K K Lee; Wen W Ma; Daniel Laheru; Ross C Donehower; Sharyn D Baker; Manuel Hidalgo
Phase I study of troxacitabine administered by continuous infusion in subjects with advanced solid malignancies.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(2):374-9.
2007: Nielka P H van Erp; Hans Gelderblom; Mats O Karlsson; Jing Li; Ming Zhao; Jan Ouwerkerk; J W R Nortier; Henk-Jan Guchelaar; Sharyn D Baker; Alex Sparreboom
Influence of CYP3A4 inhibition on the steady-state pharmacokinetics of imatinib.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(24):7394-400.
2007: Alex Sparreboom; Antonio C Wolff; Ron H J Mathijssen; Etienne Chatelut; Eric K Rowinsky; Jaap Verweij; Sharyn D Baker
Evaluation of alternate size descriptors for dose calculation of anticancer drugs in the obese.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(30):4707-13.
2007: Jing Li; Ming Zhao; Ping He; Manuel Hidalgo; Sharyn D Baker
Differential metabolism of gefitinib and erlotinib by human cytochrome P450 enzymes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(12):3731-7.
2007: Yoshinori Kato; Baasil Okollie; Venu Raman; Farhad Vesuna; Ming Zhao; Sharyn D Baker; Zaver M Bhujwalla; Dmitri Artemov
Contributing factors of temozolomide resistance in MCF-7 tumor xenograft models.
Cancer biology & therapy 2007;6(6):891-7.
2007: Hongwei Wang; Haiyan Huang; Hao Li; Denise G Teotico; Michael Sinz; Sharyn D Baker; Jeffrey Staudinger; Ganjam V Kalpana; Matthew R Redinbo; Sridhar Mani
Activated pregnenolone X-receptor is a target for ketoconazole and its analogs.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(8):2488-95.
2007: Jing Li; George Cusatis; Julie R Brahmer; Alex Sparreboom; Robert W Robey; Susan E Bates; Manuel Hidalgo; Sharyn D Baker
Association of variant ABCG2 and the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitors in cancer patients.
Cancer biology & therapy 2007;6(3):432-8.
2007: Ming Zhao; MICHELLE RUDEK-RENAUT; Ping He; Frank-Thorsten Hafner; Martin Radtke; John J Wright; B Douglas Smith; Wells A Messersmith; Manuel Hidalgo; Sharyn D Baker
A rapid and sensitive method for determination of sorafenib in human plasma using a liquid chromatography/tandem mass spectrometry assay.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;846(1-2):1-7.
2007: Ming Zhao; MICHELLE RUDEK-RENAUT; Aleksandr Mnasakanyan; Carol Hartke; Roberto Pili; Sharyn D Baker
A liquid chromatography/tandem mass spectrometry assay to quantitate MS-275 in human plasma.
Journal of pharmaceutical and biomedical analysis 2007;43(2):784-7.
2007: Wells A Messersmith; MICHELLE RUDEK-RENAUT; Sharyn D Baker; Ming Zhao; Connie Collins; A Dimitrios Colevas; Ross C Donehower; Michael A Carducci; Antonio C Wolff
Phase I study of continuous weekly dosing of dimethylamino benzoylphenylurea (BPU) in patients with solid tumours.
European journal of cancer (Oxford, England : 1990) 2007;43(1):78-86.
2006: George Cusatis; Vanesa Gregorc; Jing Li; Anna Spreafico; Roxann G Ingersoll; Jaap Verweij; Vienna Ludovini; Eugenio Villa; Manuel Hidalgo; Alex Sparreboom; Sharyn D Baker
Pharmacogenetics of ABCG2 and adverse reactions to gefitinib.
Journal of the National Cancer Institute 2006;98(23):1739-42.
2006: Jing Li; Mats O Karlsson; Julie R Brahmer; Avery Spitz; Ming Zhao; Manuel Hidalgo; Sharyn D Baker
CYP3A phenotyping approach to predict systemic exposure to EGFR tyrosine kinase inhibitors.
Journal of the National Cancer Institute 2006;98(23):1714-23.
2006: Jill Gilbert; Michael A Carducci; Sharyn D Baker; Elizabeth Dees; Ross C Donehower
A Phase I study of the oral antimetabolite, CS-682, administered once daily 5 days per week in patients with refractory solid tumor malignancies.
Investigational new drugs 2006;24(6):499-508.
2006: Arti Hurria; Mark T Fleming; Sharyn D Baker; W Kevin Kelly; Katie Cutchall; Katherine S Panageas; James Caravelli; Henry Yeung; Mark G Kris; Jorge Gomez; Vincent A Miller; Gabriella D'Andrea-Carlino; Howard I Scher; Larry Norton; Clifford Hudis
Pharmacokinetics and toxicity of weekly docetaxel in older patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 1):6100-5.
2006: MICHELLE RUDEK-RENAUT; Ming Zhao; Ping He; Wells A Messersmith; Sharyn D Baker
Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ABT-751, ABT-751 glucuronide, and ABT-751 sulfate in human plasma for clinical pharmacology studies.
Journal of pharmaceutical and biomedical analysis 2006;42(2):253-60.
2006: Victoria Sinibaldi; Kathy Elza-Brown; Jill Schmidt; Mario A Eisenberger; Eli Rosenbaum; Samuel R Denmeade; Roberto Pili; JANET WALCZAK; Sharyn D Baker; Marianna Zahurak; Michael A Carducci
Phase II evaluation of docetaxel plus exisulind in patients with androgen independent prostate carcinoma.
American journal of clinical oncology 2006;29(4):395-8.
2006: Erin R Gardner; Herman Burger; Ron van Schaik; Allan T van Oosterom; Ernst A de Bruijn; Gunther Guetens; Hans Prenen; Floris A de Jong; Sharyn D Baker; Susan E Bates; William D Figg; Jaap Verweij; Alex Sparreboom; Kees Nooter
Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib.
Clinical pharmacology and therapeutics 2006;80(2):192-201.
2006: Jing Li; Julie R Brahmer; Wells A Messersmith; Manuel Hidalgo; Sharyn D Baker
Binding of gefitinib, an inhibitor of epidermal growth factor receptor-tyrosine kinase, to plasma proteins and blood cells: in vitro and in cancer patients.
Investigational new drugs 2006;24(4):291-7.
2006: Sharyn D Baker; Alex Sparreboom
Predicting vinorelbine disposition and toxicity: does BSA provide more than a "bad statistical association"?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(16):2412-3.
2006: Carlton K K Lee; Eric K Rowinsky; Jing Li; Francis Giles; Malcolm J Moore; Manuel Hidalgo; Edmund Capparelli; Jacques Jolivet; Sharyn D Baker
Population pharmacokinetics of troxacitabine, a novel dioxolane nucleoside analogue.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 1):2158-65.
2006: Wells A Messersmith; Sharyn D Baker; Lance K Lassiter; Rana A Sullivan; Kimberly Dinh; Virna I Almuete; John J Wright; Ross C Donehower; Michael A Carducci; Deborah K Armstrong
Phase I trial of bortezomib in combination with docetaxel in patients with advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(4):1270-5.
2006: Catalin Mita; Christopher J Sweeney; Sharyn D Baker; Andrew Goetz; Lisa A Hammond; Amita Patnaik; Anthony W Tolcher; Miguel A Villalona-Calero; Alan B Sandler; Tuhin Chaudhuri; Kathleen Molpus; Jane E Latz; Lorinda Simms; Ajai K Chaudhary; Robert D Johnson; Eric K Rowinsky; Chris H Takimoto
Phase I and pharmacokinetic study of pemetrexed administered every 3 weeks to advanced cancer patients with normal and impaired renal function.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(4):552-62.
2006: Christopher J Sweeney; Chris H Takimoto; Jane E Latz; Sharyn D Baker; Daryl J Murry; James H Krull; Karen Fife; Linda Battiato; Ann Cleverly; Ajai K Chaudhary; Tuhin Chaudhuri; Alan B Sandler; Catalin Mita; Eric K Rowinsky
Two drug interaction studies evaluating the pharmacokinetics and toxicity of pemetrexed when coadministered with aspirin or Ibuprofen in patients with advanced cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(2):536-42.
2006: Satoshi Murata; Scott L Kominsky; Mustafa Vali; Zhe Zhang; Elizabeth Garrett-Mayer; Dorian Korz; David L Huso; Sharyn D Baker; James Barber; Elizabeth M Jaffee; Richard T. Reilly; Saraswati Sukumar
Ductal access for prevention and therapy of mammary tumors.
Cancer research 2006;66(2):638-45.
2006: Sharyn D Baker; Alex Sparreboom; Jaap Verweij
Clinical pharmacokinetics of docetaxel : recent developments.
Clinical pharmacokinetics 2006;45(3):235-52.
2005: MICHELLE RUDEK-RENAUT; Ming Zhao; Ping He; Yelena Zabelina; Runyan Jin; Wells A Messersmith; Antonio C Wolff; Sharyn D Baker
Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate dimethyl benzoylphenylurea (BPU) and its five metabolites in human plasma and urine for clinical pharmacology studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;828(1-2):41-54.
2005: MICHELLE RUDEK-RENAUT; Ming Zhao; Nicola F Smith; Robert W Robey; Ping He; Gurulingappa Hallur; Saeed R Khan; Manuel Hidalgo; Antonio Jimeno; A Dimitrios Colevas; Wells A Messersmith; Antonio C Wolff; Sharyn D Baker
In vitro and in vivo clinical pharmacology of dimethyl benzoylphenylurea, a novel oral tubulin-interactive agent.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(23):8503-11.
2005: Nielka P H van Erp; Sharyn D Baker; Ming Zhao; MICHELLE RUDEK-RENAUT; Henk-Jan Guchelaar; J W R Nortier; Alex Sparreboom; Hans Gelderblom
Effect of milk thistle (Silybum marianum) on the pharmacokinetics of irinotecan.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7800-6.
2005: Alex Sparreboom; Sharyn D Baker; Jaap Verweij
Paclitaxel repackaged in an albumin-stabilized nanoparticle: handy or just a dandy?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(31):7765-7.
2005: Erin R Lepper; Sharyn D Baker; Matthew G Permenter; Nicole Ries; Ron van Schaik; Paul W Schenk; Douglas K Price; Danielle Ahn; Nicola F Smith; George Cusatis; Roxann G Ingersoll; Susan E Bates; Ron H J Mathijssen; Jaap Verweij; William D Figg; Alex Sparreboom
Effect of common CYP3A4 and CYP3A5 variants on the pharmacokinetics of the cytochrome P450 3A phenotyping probe midazolam in cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(20):7398-404.
2005: MICHELLE RUDEK-RENAUT; Ming Zhao; Ping He; Carol Hartke; Jill Gilbert; Steven D Gore; Michael A Carducci; Sharyn D Baker
Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(17):3906-11.
2005: Ming Zhao; Carol Hartke; Antonio Jimeno; Jing Li; Ping He; Yelena Zabelina; Manuel Hidalgo; Sharyn D Baker
Specific method for determination of gefitinib in human plasma, mouse plasma and tissues using high performance liquid chromatography coupled to tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;819(1):73-80.
2005: Surasak Phuphanich; Sharyn D Baker; Stuart A Grossman; Kathryn Carson; Mark R Gilbert; Joy D Fisher; Michael A Carducci
Oral sodium phenylbutyrate in patients with recurrent malignant gliomas: a dose escalation and pharmacologic study.
Neuro-oncology 2005;7(2):177-82.
2005: MICHELLE RUDEK-RENAUT; Carol Hartke; Yelena Zabelina; Ming Zhao; Pamela New; Sharyn D Baker
A sensitive method for determination of COL-3, a chemically modified tetracycline, in human plasma using high-performance liquid chromatography and ultraviolet detection.
Journal of pharmaceutical and biomedical analysis 2005;37(4):751-6.
2005: Albert J ten Tije; Jaap Verweij; Michael A Carducci; Wilfried J Graveland; Theresa Rogers; Tatjana Pronk; M P Verbruggen; Fitzroy W Dawkins; Sharyn D Baker
Prospective evaluation of the pharmacokinetics and toxicity profile of docetaxel in the elderly.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(6):1070-7.
2005: Ming Zhao; MICHELLE RUDEK-RENAUT; Ping He; B Douglas Smith; Sharyn D Baker
Validation and implementation of a method for determination of bryostatin 1 in human plasma by using liquid chromatography/tandem mass spectrometry.
Analytical biochemistry 2005;337(1):143-8.
2005: Elizabeth Dees; Sharyn D Baker; Seamus O'Reilly; MICHELLE RUDEK-RENAUT; Susan B Davidson; Cheryl Aylesworth; Kathy Elza-Brown; Michael A Carducci; Ross C Donehower
A phase I and pharmacokinetic study of short infusions of UCN-01 in patients with refractory solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):664-71.
2005: Sharyn D Baker; Jing Li; Albert J ten Tije; William D Figg; Wilfried J Graveland; Jaap Verweij; Alex Sparreboom
Relationship of systemic exposure to unbound docetaxel and neutropenia.
Clinical pharmacology and therapeutics 2005;77(1):43-53.
2004: Ming Zhao; MICHELLE RUDEK-RENAUT; Ping He; Carol Hartke; Steven D Gore; Michael A Carducci; Sharyn D Baker
Quantification of 5-azacytidine in plasma by electrospray tandem mass spectrometry coupled with high-performance liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;813(1-2):81-8.
2004: Sharyn D Baker; Ron van Schaik; Laurent P Rivory; Albert J ten Tije; Kimberly Dinh; Wilfried J Graveland; Paul W Schenk; Kellie A Charles; Stephen J Clarke; Michael A Carducci; William P McGuire; Fitzroy W Dawkins; Hans Gelderblom; Jaap Verweij; Alex Sparreboom
Factors affecting cytochrome P-450 3A activity in cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8341-50.
2004: Maria L Amador; Darin Oppenheimer; Sofia Perea; Anirban Maitra; George Cusatis; George Cusati; Christine A Iacobuzio-Donahue; Sharyn D Baker; Raheela Ashfaq; Chris Takimoto; Arlene A Forastiere; Manuel Hidalgo
An epidermal growth factor receptor intron 1 polymorphism mediates response to epidermal growth factor receptor inhibitors.
Cancer research 2004;64(24):9139-43.
2004: Ming Zhao; Sharyn D Baker; Xiaohua Yan; Yiyu Zhao; William W Wright; Barry R Zirkin; Jonathan P Jarow
Simultaneous determination of steroid composition of human testicular fluid using liquid chromatography tandem mass spectrometry.
Steroids 2004;69(11-12):721-6.
2004: Albert J ten Tije; Walter J Loos; Ming Zhao; Sharyn D Baker; Roelien H Enting; Hans van der Meulen; Jaap Verweij; Alex Sparreboom
Limited cerebrospinal fluid penetration of docetaxel.
Anti-cancer drugs 2004;15(7):715-8.
2004: Milin R Acharya; Sharyn D Baker; Jaap Verweij; William D Figg; Alex Sparreboom
Determination of fraction unbound docetaxel using microequilibrium dialysis.
Analytical biochemistry 2004;331(1):192-4.
2004: MICHELLE RUDEK-RENAUT; Yelena Zabelina; Ming Zhao; Antonio C Wolff; Sharyn D Baker
A method for determination of dimethyl benzoylphenyl urea (BPU) in human plasma by using LC/UV.
Biomedical chromatography : BMC 2004;18(5):282-7.
2004: Frederike K Engels; Albert J ten Tije; Sharyn D Baker; Carlton K K Lee; Walter J Loos; Arnold G Vulto; Jaap Verweij; Alex Sparreboom
Effect of cytochrome P450 3A4 inhibition on the pharmacokinetics of docetaxel.
Clinical pharmacology and therapeutics 2004;75(5):448-54.
2004: MICHELLE RUDEK-RENAUT; Alex Sparreboom; Elizabeth Garrett-Mayer; Deborah K Armstrong; Antonio C Wolff; Jaap Verweij; Sharyn D Baker
Factors affecting pharmacokinetic variability following doxorubicin and docetaxel-based therapy.
European journal of cancer (Oxford, England : 1990) 2004;40(8):1170-8.
2004: Sharyn D Baker; Ming Zhao; Carlton K K Lee; Jaap Verweij; Yelena Zabelina; Julie R Brahmer; Antonio C Wolff; Alex Sparreboom; Michael A Carducci
Comparative pharmacokinetics of weekly and every-three-weeks docetaxel.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(6):1976-83.
2004: Sharyn D Baker; Ming Zhao; Ping He; Michael A Carducci; Jaap Verweij; Alex Sparreboom
Simultaneous analysis of docetaxel and the formulation vehicle polysorbate 80 in human plasma by liquid chromatography/tandem mass spectrometry.
Analytical biochemistry 2004;324(2):276-84.
2004: MICHELLE RUDEK-RENAUT; Ross C Donehower; Paul Statkevich; Vijay K Batra; David L Cutler; Sharyn D Baker
Temozolomide in patients with advanced cancer: phase I and pharmacokinetic study.
Pharmacotherapy 2004;24(1):16-25.
2003: Ming Zhao; Yelena Zabelina; MICHELLE RUDEK-RENAUT; Antonio C Wolff; Sharyn D Baker
A rapid and sensitive method for determination of dimethyl benzoylphenyl urea in human plasma by using LC/MS/MS.
Journal of pharmaceutical and biomedical analysis 2003;33(4):725-33.
2003: Albert J ten Tije; Walter J Loos; Jaap Verweij; Sharyn D Baker; Kimberly Dinh; William D Figg; Alex Sparreboom
Disposition of polyoxyethylated excipients in humans: implications for drug safety and formulation approaches.
Clinical pharmacology and therapeutics 2003;74(5):509-10.
2003: Walter J Loos; Sharyn D Baker; Jaap Verweij; Joke G Boonstra; Alex Sparreboom
Clinical pharmacokinetics of unbound docetaxel: role of polysorbate 80 and serum proteins.
Clinical pharmacology and therapeutics 2003;74(4):364-71.
2003: Ramaswamy Govindan; William Read; Joan Faust; Kathryn Trinkaus; Margaret K Ma; Sharyn D Baker; howard mcleod; Michael C Perry
Phase II study of docetaxel and irinotecan in metastatic or recurrent esophageal cancer: a preliminary report.
Oncology (Williston Park, N.Y.) 2003;17(9 Suppl 8):27-31.
2003: Antonio C Wolff; Ross C Donehower; M Katherine Carducci; Michael A Carducci; Julie R Brahmer; Yelena Zabelina; Matthews O Bradley; Forrest H Anthony; Charles S Swindell; Philip A Witman; Nigel L Webb; Sharyn D Baker
Phase I study of docosahexaenoic acid-paclitaxel: a taxane-fatty acid conjugate with a unique pharmacology and toxicity profile.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 1):3589-97.
2003: Ron H J Mathijssen; Sharon Marsh; Mats O Karlsson; Rujia Xie; Sharyn D Baker; Jaap Verweij; Alex Sparreboom; howard mcleod
Irinotecan pathway genotype analysis to predict pharmacokinetics.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3246-53.
2003: Ming Zhao; Ping He; MICHELLE RUDEK-RENAUT; Manuel Hidalgo; Sharyn D Baker
Specific method for determination of OSI-774 and its metabolite OSI-420 in human plasma by using liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;793(2):413-20.
2003: Hans Gelderblom; Sharyn D Baker; Ming Zhao; Jaap Verweij; Alex Sparreboom
Distribution of paclitaxel in plasma and cerebrospinal fluid.
Anti-cancer drugs 2003;14(5):365-8.
2003: Alex Sparreboom; Antonio C Wolff; Jaap Verweij; Yelena Zabelina; Desirée M van Zomeren; Gregory L McIntire; Charles S Swindell; Ross C Donehower; Sharyn D Baker
Disposition of docosahexaenoic acid-paclitaxel, a novel taxane, in blood: in vitro and clinical pharmacokinetic studies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(1):151-9.
2002: Sharyn D Baker; Jaap Verweij; Eric K Rowinsky; Ross C Donehower; Jan H M Schellens; Louise B. Grochow; Alex Sparreboom
Role of body surface area in dosing of investigational anticancer agents in adults, 1991-2001.
Journal of the National Cancer Institute 2002;94(24):1883-8.
2002: Alex Sparreboom; Ming Zhao; Julie R Brahmer; Jaap Verweij; Sharyn D Baker
Determination of the docetaxel vehicle, polysorbate 80, in patient samples by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;773(2):183-90.
2002: Karl Bélanger; Malcolm Moore; Sharyn D Baker; Jeanne Dionne; Martha Maclean; Jacques Jolivet; Lillian Siu; Denis Soulières; Nancy Wainman; Lesley Seymour
Phase I and pharmacokinetic study of novel L-nucleoside analog troxacitabine given as a 30-minute infusion every 21 days.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(10):2567-74.
2002: Clet Niyikiza; Sharyn D Baker; David E Seitz; Jackie M Walling; Katrina Nelson; James J Rusthoven; Sally P Stabler; Paolo Paoletti; A Hilary Calvert; Robert H Allen
Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy.
Molecular cancer therapeutics 2002;1(7):545-52.
2002: Francis Giles; Guillermo Garcia-Manero; Jorge E Cortes; Sharyn D Baker; Carole B Miller; Susan M O'Brien; Deborah A Thomas; Michael Andreeff; Carol Bivins; Jacques Jolivet; Hagop M Kantarjian
Phase II study of troxacitabine, a novel dioxolane nucleoside analog, in patients with refractory leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(3):656-64.
2002: Johann S de Bono; Joseph Stephenson; Sharyn D Baker; Manuel Hidalgo; Amita Patnaik; Lisa A Hammond; Geoffrey Weiss; Andrew Goetz; Lillian Siu; Cecilia Simmons; Jacques Jolivet; Eric K Rowinsky
Troxacitabine, an L-stereoisomeric nucleoside analog, on a five-times-daily schedule: a phase I and pharmacokinetic study in patients with advanced solid malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(1):96-109.
2001: Matthews O Bradley; Nigel L Webb; Forrest H Anthony; P Devanesan; Philip A Witman; S Hemamalini; M C Chander; Sharyn D Baker; L He; Susan B. Horwitz; Charles S Swindell
Tumor targeting by covalent conjugation of a natural fatty acid to paclitaxel.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(10):3229-38.
2001: J Gilbert; Sharyn D Baker; M Kathy Bowling; Louise B. Grochow; William D Figg; Yelena Zabelina; Ross C Donehower; Michael A Carducci
A phase I dose escalation and bioavailability study of oral sodium phenylbutyrate in patients with refractory solid tumor malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2292-300.
2001: Matthews O Bradley; Charles S Swindell; Forrest H Anthony; Philip A Witman; P Devanesan; Nigel L Webb; Sharyn D Baker; Antonio C Wolff; Ross C Donehower
Tumor targeting by conjugation of DHA to paclitaxel.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):233-6.
2001: Francis Giles; Jorge E Cortes; Sharyn D Baker; Deborah A Thomas; Susan O'Brien; Terry L Smith; Miloslav Beran; Carol Bivins; J Jolivet; Hagop M Kantarjian
Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(3):762-71.
2000: S Gail Eckhardt; Sharyn D Baker; Carolyn D Britten; Manuel Hidalgo; Lillian Siu; Lisa A Hammond; Miguel A Villalona-Calero; Sally A Felton; Ronald L Drengler; John Kuhn; Gary M Clark; S L Smith; John R MacDonald; C Smith; Judy Moczygemba; Steven D Weitman; Daniel Von Hoff; Eric K Rowinsky
Phase I and pharmacokinetic study of irofulven, a novel mushroom-derived cytotoxin, administered for five consecutive days every four weeks in patients with advanced solid malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(24):4086-97.
2000: Sharyn D Baker
Pharmacology of fluorinated pyrimidines: eniluracil.
Investigational new drugs 2000;18(4):373-81.
2000: Carolyn D Britten; Sharyn D Baker; Louis Denis; T Johnson; Ronald L Drengler; Lillian L Siu; K Duchin; John Kuhn; Eric K Rowinsky
Oral paclitaxel and concurrent cyclosporin A: targeting clinically relevant systemic exposure to paclitaxel.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3459-68.
2000: Sharyn D Baker; R B Diasio; Seamus O'Reilly; V S Lucas; SP Khor; SE Sartorius; Ross C Donehower; Louise B. Grochow; Thomas Spector; JA Hohneker; Eric K Rowinsky
Phase I and pharmacologic study of oral fluorouracil on a chronic daily schedule in combination with the dihydropyrimidine dehydrogenase inactivator eniluracil.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(4):915-26.
2000: Carolyn D Britten; Eric K Rowinsky; Sharyn D Baker; Geoffrey R Weiss; Lon Smith; Joseph Stephenson; M Rothenberg; Leslie Ann Smetzer; J Cramer; W Collins; Daniel Von Hoff; S Gail Eckhardt
A phase I and pharmacokinetic study of the mitochondrial-specific rhodacyanine dye analog MKT 077.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(1):42-9.
1999: Lisa A Hammond; John R Eckardt; Sharyn D Baker; S Gail Eckhardt; Margaret Dugan; K Forral; P Reidenberg; Paul Statkevich; Geoffrey R Weiss; David A Rinaldi; Daniel Von Hoff; Eric K Rowinsky
Phase I and pharmacokinetic study of temozolomide on a daily-for-5-days schedule in patients with advanced solid malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(8):2604-13.
1999: Carolyn D Britten; Eric K Rowinsky; Sharyn D Baker; S S Agarwala; John R Eckardt; RE Barrington; Sami Diab; Lisa A Hammond; T Johnson; Miguel A Villalona-Calero; U Fraass; Paul Statkevich; Daniel Von Hoff; S Gail Eckhardt
A Phase I and pharmacokinetic study of temozolomide and cisplatin in patients with advanced solid malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(7):1629-37.
1999: S Gail Eckhardt; Jinee Rizzo; K R Sweeney; Gillian F Cropp; Sharyn D Baker; Maura Kraynak; John Kuhn; Miguel A Villalona-Calero; L Hammond; Geoffrey Weiss; A Thurman; Lon Smith; Ronald L Drengler; John R Eckardt; Judy Moczygemba; Alison L Hannah; Daniel Von Hoff; Eric K Rowinsky
Phase I and pharmacologic study of the tyrosine kinase inhibitor SU101 in patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(4):1095-104.
1999: Sharyn D Baker; M Wirth; Paul Statkevich; P Reidenberg; Kevin B Alton; SE Sartorius; Margaret Dugan; David Cutler; Vijay K Batra; Louise B. Grochow; Ross C Donehower; Eric K Rowinsky
Absorption, metabolism, and excretion of 14C-temozolomide following oral administration to patients with advanced cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(2):309-17.
1999: Sami Diab; Sharyn D Baker; A Joshi; Howard A Burris; P W Cobb; Miguel A Villalona-Calero; S Gail Eckhardt; Geoffrey R Weiss; Gladys I Rodriguez; Ronald L Drengler; Maura Kraynak; L Hammond; M Finizio; Daniel Von Hoff; Eric K Rowinsky
A phase I and pharmacokinetic study of losoxantrone and paclitaxel in patients with advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(2):299-308.
1998: Miguel A Villalona-Calero; Sharyn D Baker; L Hammond; Cheryl Aylesworth; S Gail Eckhardt; Maura Kraynak; Robert J Fram; Steven Fischkoff; R Velagapudi; D Toppmeyer; B Razvillas; K Jakimowicz; Daniel Von Hoff; Eric K Rowinsky
Phase I and pharmacokinetic study of the water-soluble dolastatin 15 analog LU103793 in patients with advanced solid malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(8):2770-9.
1998: S Gail Eckhardt; Sharyn D Baker; John R Eckardt; Thomas G Burke; D L Warner; John Kuhn; G Rodriguez; S Fields; A Thurman; Lon Smith; Mace L Rothenberg; L White; Paul Wissel; R Kunka; S DePee; D Littlefield; Howard A Burris; Daniel Von Hoff; Eric K Rowinsky
Phase I and pharmacokinetic study of GI147211, a water-soluble camptothecin analogue, administered for five consecutive days every three weeks.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(3):595-604.
1998: Eric K Rowinsky; Sharyn D Baker; Kathleen Burks; Seamus O'Reilly; Ross C Donehower; Louise B. Grochow
High-dose topotecan with granulocyte-colony stimulating factor in fluoropyrimidine-refractory colorectal cancer: a phase II and pharmacodynamic study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1998;9(2):173-80.
1998: Seamus O'Reilly; Sharyn D Baker; SE Sartorius; Eric K Rowinsky; M Finizio; G M Lubiniecki; Louise B. Grochow; J E Gray; Henry J Pieniaszek; Ross C Donehower
A phase I and pharmacologic study of DMP 840 administered by 24-hour infusion.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1998;9(1):101-4.
1997: Sharyn D Baker; Louise B. Grochow
Pharmacology of cancer chemotherapy in the older person.
Clinics in geriatric medicine 1997;13(1):169-83.
1996: Eric K Rowinsky; Scott H Kaufmann; Sharyn D Baker; Carole B Miller; SE Sartorius; M K Bowling; Tian Ling Chen; Ross C Donehower; Steven D Gore
A phase I and pharmacological study of topotecan infused over 30 minutes for five days in patients with refractory acute leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(12):1921-30.
1996: Sharyn D Baker; SP Khor; Alex A. Adjei; M Doucette; T Spector; Ross C Donehower; Louise B. Grochow; SE Sartorius; D A Noe; JA Hohneker; Eric K Rowinsky
Pharmacokinetic, oral bioavailability, and safety study of fluorouracil in patients treated with 776C85, an inactivator of dihydropyrimidine dehydrogenase.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(12):3085-96.
1996: Eric K Rowinsky; Scott H Kaufmann; Sharyn D Baker; Louise B. Grochow; Tian Ling Chen; D Peereboom; M K Bowling; SE Sartorius; David S Ettinger; Arlene A Forastiere; Ross C Donehower
Sequences of topotecan and cisplatin: phase I, pharmacologic, and in vitro studies to examine sequence dependence.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(12):3074-84.
1996: Wayne L Furman; Sharyn D Baker; Charles B Pratt; Jaime Rivera; William Evans; Clinton F Stewart
Escalating systemic exposure of continuous infusion topotecan in children with recurrent acute leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(5):1504-11.
1996: Sharyn D Baker; Richard L Heideman; W R Crom; John Frank Kuttesch; Amar Gajjar; Clinton F Stewart
Cerebrospinal fluid pharmacokinetics and penetration of continuous infusion topotecan in children with central nervous system tumors.
Cancer chemotherapy and pharmacology 1996;37(3):195-202.
1995: Sharyn D Baker; Louise B. Grochow; Ross C Donehower
Should anticancer drug doses be adjusted in the obese patient?
Journal of the National Cancer Institute 1995;87(5):333-4.
1995: Sharyn D Baker; Randy M Wadkins; Clinton F Stewart; William T Beck; Mary K Danks
Cell cycle analysis of amount and distribution of nuclear DNA topoisomerase I as determined by fluorescence digital imaging microscopy.
Cytometry 1995;19(2):134-45.
1994: Clinton F Stewart; Sharyn D Baker; Richard L Heideman; D Jones; W R Crom; Charles B Pratt
Clinical pharmacodynamics of continuous infusion topotecan in children: systemic exposure predicts hematologic toxicity.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(9):1946-54.