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Nora Klöting

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John Heiker; Matthias Kern; Matthias Blüher; Miriam Dreßler; Gesine Flehmig; Joanna Kosacka; Peter Kovacs; Tobias Lohmann; Edward Shang; Michael Stumvoll; Nora Klöting
Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity.
F Bernhard; Antje Berthold; Matthias Blüher; P Büttner; D Friebe; Wieland Kiess; Nora Klöting; Peter Kovacs; K Landgraf; Antje Körner
Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology.
Joanna Krist; Tobias Lohmann; Andreas Oberbach; Michael R Schön; Edward Shang; Michael Stumvoll; Katharina Wieder; Tobias Wiesner; Arne Dietrich; Miriam Dreßler; Mathias Fasshauer; Daniel Gärtner; Nora Klöting; Susan Kralisch; Matthias Blüher
Effects of weight loss and exercise on apelin serum concentrations and adipose tissue expression in human obesity.

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2013: John Heiker; Matthias Kern; Matthias Blüher; Miriam Dreßler; Gesine Flehmig; Joanna Kosacka; Peter Kovacs; Tobias Lohmann; Edward Shang; Michael Stumvoll; Nora Klöting
Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity.
Obesity (Silver Spring, Md.) 2013;21(3):529-34.
2013: F Bernhard; Antje Berthold; Matthias Blüher; P Büttner; D Friebe; Wieland Kiess; Nora Klöting; Peter Kovacs; K Landgraf; Antje Körner
Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology.
Diabetologia 2013;56(2):311-22.
2013: Joanna Krist; Tobias Lohmann; Andreas Oberbach; Michael R Schön; Edward Shang; Michael Stumvoll; Katharina Wieder; Tobias Wiesner; Arne Dietrich; Miriam Dreßler; Mathias Fasshauer; Daniel Gärtner; Nora Klöting; Susan Kralisch; Matthias Blüher
Effects of weight loss and exercise on apelin serum concentrations and adipose tissue expression in human obesity.
Obesity facts 2013;6(1):57-69.
2013: John Heiker; Nora Klöting
Replication initiator 1 in adipose tissue function and human obesity.
Vitamins and hormones 2013;91():97-105.
2012: H Serke; Matthias Blüher; S Kallendrusch; Nora Klöting; Joanna Kosacka; Marcin Nowicki; T Schröder; Katharina Spanel-Borowski
Leptin-deficient (ob/ob) mouse ovaries show fatty degeneration, enhanced apoptosis and decreased expression of steroidogenic acute regulatory enzyme.
International journal of obesity (2005) 2012;36(8):1047-53.
2012: Rima Chakaroun; Miriam Dreßler; Mathias Fasshauer; Gesine Flehmig; Matthias Kern; Nora Klöting; Tobias Lohmann; Andreas Oberbach; Matthias Raschpichler; Michael R Schön; Edward Shang; Michael Stumvoll; Matthias Blüher
Effects of weight loss and exercise on chemerin serum concentrations and adipose tissue expression in human obesity.
Metabolism: clinical and experimental 2012;61(5):706-14.
2012: Matthias Blüher; Martin Fiedler; Yftach Gepner; Rachel Golan; Yaakov Henkin; Nora Klöting; Eitan Rubin; Assaf Rudich; Dan Schwarzfuchs; Meir J Stampfer; Michael Stumvoll; Joachim Thiery; Iris Shai
Two patterns of adipokine and other biomarker dynamics in a long-term weight loss intervention.
Diabetes care 2012;35(2):342-9.
2012: Matthias Kern; Matthias Blüher; John Heiker; Anja Knigge; Joanna Kosacka; Peter Kovacs; Michael Stumvoll; Nora Klöting
C57BL/6JRj mice are protected against diet induced obesity (DIO).
Biochemical and biophysical research communications 2012;417(2):717-20.
2012: Martin T Gericke; Nora Klöting; Joanna Kosacka; Marcin Nowicki; Thomas Schröder; Katharina Spanel-Borowski
Neuropeptide Y impairs insulin-stimulated translocation of glucose transporter 4 in 3T3-L1 adipocytes through the Y1 receptor.
Molecular and cellular endocrinology 2012;348(1):27-32.
2012: Matthias Kern; Thomas Klein; Nora Klöting; Michael Mark; Heiko G Niessen; Detlef Stiller; Leo Thomas; Matthias Blüher
Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity.
PloS one 2012;7(6):e38744.
2012: Joanna Kosacka; Marcin Nowicki; Heike Serke; Michael Stumvoll; Ingo Bechmann; Matthias Kern; Nora Klöting; Matthias Blüher
COMP-angiopoietin-1 recovers molecular biomarkers of neuropathy and improves vascularisation in sciatic nerve of ob/ob mice.
PloS one 2012;7(3):e32881.
2011: Kathrin Müller; Roy E Weiss; Kurt Werner Schmid; Marie-Christine Many; Jens Mittag; Matthias Blüher; Dagmar Führer; Nora Klöting; Knut Krohn
TSH compensates thyroid-specific IGF-I receptor knockout and causes papillary thyroid hyperplasia.
Molecular endocrinology (Baltimore, Md.) 2011;25(11):1867-79.
2011: Jeanette Bahr; Ingrid Klöting; Nora Klöting; Niels Follak
Gene expression profiling supports the role of Repin1 in the pathophysiology of metabolic syndrome.
Endocrine 2011;40(2):310-4.
2011: Jeanette Bahr; Ingrid Klöting; Nora Klöting; Barbara Wilke; Niels Follak
High-fat diet protects BB/OK rats from developing type 1 diabetes.
Diabetes/metabolism research and reviews 2011;27(6):552-6.
2011: Nora Klöting; Peter Kovacs; Michael R Schön; Michael Stumvoll; Annette G Beck-Sickinger; Mathias Fasshauer; John Heiker; M Kern; Matthias Blüher
Central vaspin administration acutely reduces food intake and has sustained blood glucose-lowering effects.
Diabetologia 2011;54(7):1819-23.
2011: J Bahr; Niels Follak; B Haertel; Nora Klöting; Barbara Wilke; Ingrid Klöting
Iddm1 and Iddm2 homozygous WOK.4BB rats develop lymphopenia, but no hyperglycemia like the BB/OK rats.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2011;119(7):395-400.
2011: Jeanette Bahr; Nora Klöting; Ingrid Klöting; Niels Follak
Transplantation of adipose tissue protects BB/OK rats from type 1 diabetes development.
Transplant immunology 2011;24(4):238-40.
2011: Julia Kovsan; Matthias Blüher; Tanya Tarnovscki; Nora Klöting; Boris Kirshtein; Liron Madar; Iris Shai; Rachel Golan; Ilana Harman-Boehm; Michael R Schön; Andrew S Greenberg; Zvulun Elazar; Nava Bashan; Assaf Rudich
Altered autophagy in human adipose tissues in obesity.
The Journal of clinical endocrinology and metabolism 2011;96(2):E268-77.
2011: Dorit Schleinitz; Nora Klöting; Yvonne Böttcher; Sara Wolf; Kerstin Dietrich; Anke Tönjes; Jana Breitfeld; Beate Enigk; Jan Halbritter; Antje Körner; Michael R Schön; Jost Jenkner; Yu-Hua Tseng; Tobias Lohmann; Miriam Dressler; Michael Stumvoll; Matthias Blüher; Peter Kovacs
Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity.
PloS one 2011;6(2):e16155.
2011: Joanna Kosacka; Thomas Schröder; Ingo Bechmann; Nora Klöting; Marcin Nowicki; Anja Mittag; Martin Gericke; Katharina Spanel-Borowski; Matthias Blüher
PACAP up-regulates the expression of apolipoprotein D in 3T3-L1 adipocytes. DRG/3T3-L1 co-cultures study.
Neuroscience research 2011;69(1):8-16.
2010: Karen Ruschke; Monica Illes; Matthias Kern; Ingrid Klöting; Mathias Fasshauer; Michael R Schön; Joanna Kosacka; Gunther Fitzl; Peter Kovacs; Michael Stumvoll; Matthias Blüher; Nora Klöting
Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes.
Biochemical and biophysical research communications 2010;400(2):246-51.
2010: Nora Klöting; Mathias Fasshauer; Arne Dietrich; Peter Kovacs; Michael R Schön; Matthias Kern; Michael Stumvoll; Matthias Blüher
Insulin-sensitive obesity.
American journal of physiology. Endocrinology and metabolism 2010;299(3):E506-15.
2010: John Heiker; Nora Klöting; Matthias Blüher; Annette G Beck-Sickinger
Access to gram scale amounts of functional globular adiponectin from E. coli inclusion bodies by alkaline-shock solubilization.
Biochemical and biophysical research communications 2010;398(1):32-7.
2010: Dorit Schleinitz; Nora Klöting; Antje Körner; Janin Berndt; Marlene Reichenbächer; Anke Tönjes; Karen Ruschke; Yvonne Böttcher; Kerstin Dietrich; Beate Enigk; Matthias Filz; Michael R Schön; Jost Jenkner; Wieland Kiess; Michael Stumvoll; Matthias Blüher; Peter Kovacs
Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression.
Obesity (Silver Spring, Md.) 2010;18(6):1218-25.
2010: Dorit Schleinitz; Solveig Carmienke; Yvonne Böttcher; Anke Tönjes; Janin Berndt; Nora Klöting; Beate Enigk; Ines Müller; Kerstin Dietrich; Jana Breitfeld; Gerhard Scholz; Stefan Engeli; Michael Stumvoll; Matthias Blüher; Peter Kovacs
Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity.
Pharmacogenomics 2010;11(5):693-702.
2009: Yvonne Böttcher; Hanne Unbehauen; Nora Klöting; Karen Ruschke; Antje Körner; Dorit Schleinitz; Anke Tönjes; Beate Enigk; Sara Wolf; Kerstin Dietrich; Moritz Koriath; Gerhard Scholz; Yu-Hua Tseng; Arne Dietrich; Michael R Schön; Wieland Kiess; Michael Stumvoll; Matthias Blüher; Peter Kovacs
Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity.
Diabetes 2009;58(9):2119-28.
2009: Matthias Blüher; Nava Bashan; Iris Shai; Ilana Harman-Boehm; Tanya Tarnovscki; Eliezer Avinaoch; Michael Stumvoll; Arne Dietrich; Nora Klöting; Assaf Rudich
Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity.
The Journal of clinical endocrinology and metabolism 2009;94(7):2507-15.
2009: Romy Baguhl; Barbara Wilke; Nora Klöting; Ingrid Klöting
Genes on rat chromosomes 3, 5, 10, and 16 are linked with facets of metabolic syndrome.
Obesity (Silver Spring, Md.) 2009;17(6):1215-9.
2009: Michael Ristow; Kim Zarse; Andreas Oberbach; Nora Klöting; Marc Birringer; Michael Kiehntopf; Michael Stumvoll; C Ronald Kahn; Matthias Blüher
Antioxidants prevent health-promoting effects of physical exercise in humans.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(21):8665-70.
2009: Gabriela Aust; Olaf Richter; Silvio Rohm; Christiane Kerner; Johann Hauss; Nora Klöting; Karen Ruschke; Peter Kovacs; Byung-Soo Youn; Matthias Blüher
Vaspin serum concentrations in patients with carotid stenosis.
Atherosclerosis 2009;204(1):262-6.
2009: Byung-Soo Youn; Sa Ik Bang; Nora Klöting; Ji Woo Park; Namseok Lee; Ji-Eun Oh; Kyung-Bae Pi; Tae Hee Lee; Karen Ruschke; Mathias Fasshauer; Michael Stumvoll; Matthias Blüher
Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue.
Diabetes 2009;58(3):627-36.
2009: Karen Ruschke; Henning Ebelt; Nora Klöting; Thomas Boettger; Kay Raum; Matthias Blüher; Nanette Kälin
Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice.
PloS one 2009;4(5):e5516.
2009: Nora Klöting; Susan Berthold; Peter Kovacs; Michael R Schön; Mathias Fasshauer; Karen Ruschke; Michael Stumvoll; Matthias Blüher
MicroRNA expression in human omental and subcutaneous adipose tissue.
PloS one 2009;4(3):e4699.
2008: Peter Kovacs; Janin Berndt; Karen Ruschke; Nora Klöting; Michael R Schön; Antje Körner; Michael Stumvoll; Matthias Blüher
TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus.
Metabolism: clinical and experimental 2008;57(9):1227-31.
2008: Nora Klöting; Linda Koch; Thomas Wunderlich; Matthias Kern; Karen Ruschke; Wilhelm Krone; Jens C Brüning; Matthias Blüher
Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth.
Diabetes 2008;57(8):2074-82.
2008: Nora Klöting; D Schleinitz; Karen Ruschke; Janin Berndt; Mathias Fasshauer; Anke Tönjes; Michael R Schön; Peter Kovacs; Michael Stumvoll; Matthias Blüher
Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans.
Diabetologia 2008;51(4):641-7.
2008: Janin Berndt; Susan Kralisch; Nora Klöting; Karen Ruschke; M Kern; Mathias Fasshauer; Michael R Schön; Michael Stumvoll; Matthias Blüher
Adipose triglyceride lipase gene expression in human visceral obesity.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2008;116(4):203-10.
2008: Byung-Soo Youn; Nora Klöting; Jürgen Kratzsch; Namseok Lee; Ji Woo Park; Eun-Sun Song; Karen Ruschke; Andreas Oberbach; Mathias Fasshauer; Michael Stumvoll; Matthias Blüher
Serum vaspin concentrations in human obesity and type 2 diabetes.
Diabetes 2008;57(2):372-7.
2007: Matthias Blüher; Catherine J Williams; Nora Klöting; Alex Hsi; Karen Ruschke; Andreas Oberbach; Mathias Fasshauer; Janin Berndt; Michael R Schön; Alicja Wolk; Michael Stumvoll; Christos S Mantzoros
Gene expression of adiponectin receptors in human visceral and subcutaneous adipose tissue is related to insulin resistance and metabolic parameters and is altered in response to physical training.
Diabetes care 2007;30(12):3110-5.
2007: Peter Kovacs; Michaela Geyer; Janin Berndt; Nora Klöting; Timothy E Graham; Yvonne Böttcher; Beate Enigk; Anke Tönjes; Dorit Schleinitz; Michael R Schön; Barbara B Kahn; Matthias Blüher; Michael Stumvoll
Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression.
Diabetes 2007;56(12):3095-100.
2007: Beate Kuttler; Heike Wanka; Nora Klöting; Bernhard Gerstmayer; Hans-Dieter Volk; Birgit Sawitzki; Thomas Ritter
Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats.
Journal of cellular and molecular medicine 2007;11(4):868-80.
2007: Nora Klöting; Timothy E Graham; Janin Berndt; Susan Kralisch; Peter Kovacs; Christopher J Wason; Mathias Fasshauer; Michael R Schön; Michael Stumvoll; Matthias Blüher; Barbara B Kahn
Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass.
Cell metabolism 2007;6(1):79-87.
2007: Janin Berndt; Peter Kovacs; Karen Ruschke; Nora Klöting; Mathias Fasshauer; Michael R Schön; Antje Körner; Michael Stumvoll; Matthias Blüher
Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes.
Diabetologia 2007;50(7):1472-80.
2007: Nora Klöting; Barbara Wilke; Ingrid Klöting
Triplet repeat in the Repin1 3'-untranslated region on rat chromosome 4 correlates with facets of the metabolic syndrome.
Diabetes/metabolism research and reviews 2007;23(5):406-10.
2007: Ilana Harman-Boehm; Matthias Blüher; Henry Redel; Netta Sion-Vardy; Shira Ovadia; Eliezer Avinoach; Iris Shai; Nora Klöting; Michael Stumvoll; Nava Bashan; Assaf Rudich
Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity.
The Journal of clinical endocrinology and metabolism 2007;92(6):2240-7.
2007: Nora Klöting; Michael Stumvoll; Matthias Blüher
[The biology of visceral fat].
Der Internist 2007;48(2):126-33.
2006: Matthias Blüher; Stefan Engeli; Nora Klöting; Janin Berndt; Mathias Fasshauer; Sandor Batkai; Pal Pacher; Michael R Schön; Jens Jordan; Michael Stumvoll
Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity.
Diabetes 2006;55(11):3053-60.
2006: Klemens Raile; Jürgen Klammt; Antje Garten; S Laue; Matthias Blüher; Susan Kralisch; Nora Klöting; Wieland Kiess
Glucose regulates expression of the nerve growth factor (NGF) receptors TrkA and p75NTR in rat islets and INS-1E beta-cells.
Regulatory peptides 2006;135(1-2):30-8.
2006: Yvonne Böttcher; Daniel Teupser; Beate Enigk; Janin Berndt; Nora Klöting; Michael R Schön; Joachim Thiery; Matthias Blüher; Michael Stumvoll; Peter Kovacs
Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans.
The Journal of clinical endocrinology and metabolism 2006;91(7):2725-31.
2006: Matthias Blüher; John W Bullen; Jennifer H Lee; Susan Kralisch; Mathias Fasshauer; Nora Klöting; Josef Niebauer; Michael R Schön; Catherine J Williams; Christos S Mantzoros
Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training.
The Journal of clinical endocrinology and metabolism 2006;91(6):2310-6.
2006: Andreas Oberbach; Anke Tönjes; Nora Klöting; Mathias Fasshauer; Jürgen Kratzsch; Martin W Busse; Ralf Paschke; Michael Stumvoll; Matthias Blüher
Effect of a 4 week physical training program on plasma concentrations of inflammatory markers in patients with abnormal glucose tolerance.
European journal of endocrinology / European Federation of Endocrine Societies 2006;154(4):577-85.
2006: Nora Klöting; Matthias Blüher; Ingrid Klöting
The polygenetically inherited metabolic syndrome of WOKW rats is associated with insulin resistance and altered gene expression in adipose tissue.
Diabetes/metabolism research and reviews 2006;22(2):146-54.
2006: Nora Klöting; Janin Berndt; Susan Kralisch; Peter Kovacs; Mathias Fasshauer; Michael R Schön; Michael Stumvoll; Matthias Blüher
Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes.
Biochemical and biophysical research communications 2006;339(1):430-6.
2005: Nora Klöting; Niels Follak; Ingrid Klöting
Is there an autoimmune process in bone? Gene expression studies in diabetic and nondiabetic BB rats as well as BB rat-related and -unrelated rat strains.
Physiological genomics 2005;24(1):59-64.
2005: Nora Klöting; Matthias Blüher
Extended longevity and insulin signaling in adipose tissue.
Experimental gerontology 2005;40(11):878-83.
2005: Janin Berndt; Nora Klöting; Susan Kralisch; Peter Kovacs; Mathias Fasshauer; Michael R Schön; Michael Stumvoll; Matthias Blüher
Plasma visfatin concentrations and fat depot-specific mRNA expression in humans.
Diabetes 2005;54(10):2911-6.
2005: Klemens Raile; Jürgen Klammt; S Laue; Antje Garten; Matthias Blüher; Susan Kralisch; Nora Klöting; Wieland Kiess
Glucose concentration and AMP-dependent kinase activation regulate expression of insulin receptor family members in rat islets and INS-1E beta cells.
Diabetologia 2005;48(9):1798-809.
2005: Nora Klöting; Ingrid Klöting
Visfatin: gene expression in isolated adipocytes and sequence analysis in obese WOKW rats compared with lean control rats.
Biochemical and biophysical research communications 2005;332(4):1070-2.
2005: Nora Klöting; Niels Follak; Ingrid Klöting
Diabetes per se and metabolic state influence gene expression in tissue-dependent manner of BB/OK rats.
Diabetes/metabolism research and reviews 2005;21(3):281-7.
2005: Nora Klöting; Barbara Wilke; Ingrid Klöting
Alleles on rat chromosome 4 (D4Got41-Fabp1/Tacr1) regulate subphenotypes of obesity.
Obesity research 2005;13(3):589-95.
2004: Nora Klöting; Ingrid Klöting
Congenic mapping of type 1 diabetes--protective gene(s) in an interval of 4 Mb on rat chromosome 6q32.
Biochemical and biophysical research communications 2004;323(2):388-94.
2004: Nora Klöting; Barbara Wilke; Ingrid Klöting
Phenotypic and genetic analyses of subcongenic BB.SHR rat lines shorten the region on chromosome 4 bearing gene(s) for underlying facets of metabolic syndrome.
Physiological genomics 2004;18(3):325-30.
2004: Nora Klöting; Ingrid Klöting
Genetic variation in the multifunctional transcription factor Yy1 and type 1 diabetes mellitus in the BB rat.
Molecular genetics and metabolism 2004;82(3):255-9.
2004: Nora Klöting; I Klöting; R S Jack
CD14 triggers autoimmune Type 1 diabetes in the NOD mouse.
Diabetologia 2004;47(1):151-2.
2003: Beate Kuttler; Antje Steveling; Nora Klöting; Olaf Morgenstern; Heike Wanka
Aminoguanidine downregulates expression of cytokine-induced Fas and inducible nitric oxide synthase but not cytokine-enhanced surface antigens of rat islet cells.
Biochemical pharmacology 2003;66(12):2437-48.
2003: I Klöting; M Poetsch; B Müller-Myhsok; Ilona Rjasanowski; Wolfgang Kerner; Nora Klöting
Is there relatedness between maternal lines of Type 1 diabetic patients?
Diabetologia 2003;46(3):441-2.
2003: Ingrid Klöting; Jens van den Brandt; Nora Klöting; Branislav Radović
Alleles of diabetes-resistant BN rats contribute to insulin-dependent type 1 diabetes mellitus.
Journal of autoimmunity 2003;20(2):119-23.