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William Klunk

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Ann D Cohen; Steven Dekosky; Howard J Aizenstein; Oscar L Lopez; Chester A Mathis; Eric McDade; James M Mountz; Wenzhu Mowrey; Robert D Nebes; Julie C Price; Judith A Saxton; Beth Snitz; Lisa A Weissfeld; Jeff Williamson; William E Klunk
Classification of amyloid-positivity in controls: comparison of visual read and quantitative approaches.
Jinhe Pan; Manik L Debnath; William E Klunk; Neale S Mason; Chester A Mathis; Kuo-Shyan Lin
Design, synthesis and structure-activity relationship of rhenium 2-arylbenzothiazoles as β-amyloid plaque binding agents.
Ira Driscoll; Luigi Ferrucci; William E Klunk; Michael A Kraut; Chester A Mathis; Richard J O'Brien; Olga Pletnikova; Gay Rudow; Jitka Sojkova; Juan C Troncoso; Dean F Wong; Yun Zhou; Christos Davatzikos; Susan M Resnick
Correspondence between in vivo (11)C-PiB-PET amyloid imaging and postmortem, region-matched assessment of plaques.

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2013: Ann D Cohen; Steven Dekosky; Howard J Aizenstein; Oscar L Lopez; Chester A Mathis; Eric McDade; James M Mountz; Wenzhu Mowrey; Robert D Nebes; Julie C Price; Judith A Saxton; Beth Snitz; Lisa A Weissfeld; Jeff Williamson; William E Klunk
Classification of amyloid-positivity in controls: comparison of visual read and quantitative approaches.
NeuroImage 2013;71():207-15.
2013: Jinhe Pan; Manik L Debnath; William E Klunk; Neale S Mason; Chester A Mathis; Kuo-Shyan Lin
Design, synthesis and structure-activity relationship of rhenium 2-arylbenzothiazoles as β-amyloid plaque binding agents.
Bioorganic & medicinal chemistry letters 2013;23(6):1720-6.
2012: Ira Driscoll; Luigi Ferrucci; William E Klunk; Michael A Kraut; Chester A Mathis; Richard J O'Brien; Olga Pletnikova; Gay Rudow; Jitka Sojkova; Juan C Troncoso; Dean F Wong; Yun Zhou; Christos Davatzikos; Susan M Resnick
Correspondence between in vivo (11)C-PiB-PET amyloid imaging and postmortem, region-matched assessment of plaques.
Acta neuropathologica 2012;124(6):823-31.
2012: Patrick S Murray; William R Paljug; Peter Penzes; Eric E Abrahamson; Megan C Gray; Ronald L Hamilton; RA Henteleff; Milos D Ikonomovic; Caitlin M Kirkwood; William E Klunk; Julia K Kofler; Oscar L Lopez; Robert A Sweet
β-Amyloid 42/40 ratio and kalirin expression in Alzheimer disease with psychosis.
Neurobiology of aging 2012;33(12):2807-16.
2012: Benjamin L Handen; Chester A Mathis; Julie C Price; Peter Bulova; Sheila A Cannon; Umapathy Channamalappa; Ann D Cohen; William I Cohen; William E Klunk
Imaging brain amyloid in nondemented young adults with Down syndrome using Pittsburgh compound B.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2012;8(6):496-501.
2012: Chester A Mathis; Brian J Lopresti; N Scott Mason; William E Klunk
Development of positron emission tomography β-amyloid plaque imaging agents.
Seminars in nuclear medicine 2012;42(6):423-32.
2012: David A Wolk; William E Klunk; Oscar L Lopez; Charles Madeira; Chester A Mathis; Julie C Price; Judy A Saxton; Beth E Snitz; Steven T DeKosky
Amyloid imaging in dementias with atypical presentation.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2012;8(5):389-98.
2012: Randall J Bateman; Tammie L S Benzinger; Tyler M Blazey; V Buckles; Nigel J Cairns; Anne M Fagan; Nick C Fox; Bernardino Ghetti; Alison Goate; David M Holtzman; William E Klunk; Daniel S Marcus; Ralph N Martins; Colin L Masters; Richard Mayeux; Eric McDade; John C Morris; Krista Moulder; Angela Oliver; John M Ringman; Martin N Rossor; Stephen Salloway; Anna Santacruz; Peter R Schofield; Reisa A Sperling; Xianyun Xie; Chengjie Xiong; Paul S Aisen
Clinical and biomarker changes in dominantly inherited Alzheimer's disease.
The New England journal of medicine 2012;367(9):795-804.
2012: Scott B Raymond; Julie Price; Carl Becker; Ann D Cohen; William E Klunk
Anomalous PiB enhancement in the superior sagittal and transverse venous sinuses.
Alzheimer disease and associated disorders 2012;26(2):186-90.
2012: Milos D Ikonomovic; Eric E Abrahamson; Anne D Cohen; Manik L Debnath; Steven T DeKosky; Ronald L Hamilton; Oscar L Lopez; Chester A Mathis; Katsuyoshi Mizukami; William R Paljug; Julie C Price; William E Klunk
Early AD pathology in a [C-11]PiB-negative case: a PiB-amyloid imaging, biochemical, and immunohistochemical study.
Acta neuropathologica 2012;123(3):433-47.
2012: Victor L Villemagne; Michael W Weiner; David J Brooks; Bradley T Hyman; Milos D Ikonomovic; Kenji Ishii; Clifford R Jack; William J Jagust; Keith A Johnson; William E Klunk; Robert A Koeppe; Val J Lowe; Colin L Masters; Chester A Mathis; Thomas J Montine; John C Morris; Agneta Nordberg; Ronald C Petersen; Eric M Reiman; Christopher C Rowe; Dennis J Selkoe; Reisa A Sperling; Koen Van Laere; Alexander Drzezga
Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2012;39(2):209-19.
2012: Ann D Cohen; William J Jagust; William E Klunk; Chester A Mathis; Gil D Rabinovici; Milos D Ikonomovic
Using Pittsburgh Compound B for in vivo PET imaging of fibrillar amyloid-beta.
Advances in pharmacology (San Diego, Calif.) 2012;64():27-81.
2011: William E Klunk
Amyloid imaging as a biomarker for cerebral β-amyloidosis and risk prediction for Alzheimer dementia.
Neurobiology of aging 2011;32 Suppl 1():S20-36.
2011: Ira Driscoll; Luigi Ferrucci; William E Klunk; Michael A Kraut; Chester A Mathis; Jitka Sojkova; Dean F Wong; Weiguo Ye; Yun Zhou; Yang An; Christos Davatzikos; Susan M Resnick
Lack of association between 11C-PiB and longitudinal brain atrophy in non-demented older individuals.
Neurobiology of aging 2011;32(12):2123-30.
2011: Bedda L Rosario; Lisa A Weissfeld; Charles M Laymon; Chester A Mathis; William E Klunk; Michael D Berginc; Jeffrey A James; Jessica A Hoge; Julie C Price
Inter-rater reliability of manual and automated region-of-interest delineation for PiB PET.
NeuroImage 2011;55(3):933-41.
2011: Jitka Sojkova; Ira Driscoll; Diego Iacono; Yun Zhou; Kari-Elise Codispoti; Michael A Kraut; Luigi Ferrucci; Olga Pletnikova; Chester A Mathis; William E Klunk; Richard J O'Brien; Dean F Wong; Juan C Troncoso; Susan M Resnick
In vivo fibrillar beta-amyloid detected using [11C]PiB positron emission tomography and neuropathologic assessment in older adults.
Archives of neurology 2011;68(2):232-40.
2010: Timo Grimmer; Susanne Tholen; Behrooz Hooshyar Yousefi; Panagiotis Alexopoulos; Annette Förschler; hans förstl; Gjermund Henriksen; William E Klunk; Chester A Mathis; Robert Perneczky; Christian Sorg; Alexander Kurz; Alexander Drzezga
Progression of cerebral amyloid load is associated with the apolipoprotein E ε4 genotype in Alzheimer's disease.
Biological psychiatry 2010;68(10):879-84.
2010: Susan M Resnick; Jitka Sojkova; Yun Zhou; Y An; W Ye; D P Holt; Robert F Dannals; C A Mathis; William E Klunk; Luigi Ferrucci; Michael A Kraut; Dean F Wong
Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB.
Neurology 2010;74(10):807-15.
2009: Nigel J Cairns; Milos D Ikonomovic; Tammie Benzinger; Martha Storandt; Anne M Fagan; Aarti R Shah; Lisa Taylor Reinwald; Deborah Carter; Angela Felton; David M Holtzman; Mark A Mintun; William E Klunk; John C Morris
Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report.
Archives of neurology 2009;66(12):1557-62.
2009: Timo Grimmer; Gjermund Henriksen; Hans-Jürgen Wester; hans förstl; William E Klunk; Chester A Mathis; Alexander Kurz; Alexander Drzezga
Clinical severity of Alzheimer's disease is associated with PIB uptake in PET.
Neurobiology of aging 2009;30(12):1902-9.
2009: Ann D Cohen; Julie C Price; Lisa A Weissfeld; Jeffrey James; Bedda L Rosario; Wenzhu Bi; Robert D Nebes; Judith A Saxton; Beth E Snitz; Howard J Aizenstein; David A Wolk; Steven T DeKosky; Chester A Mathis; William E Klunk
Basal cerebral metabolism may modulate the cognitive effects of Abeta in mild cognitive impairment: an example of brain reserve.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(47):14770-8.
2009: David A Wolk; William E Klunk
Update on amyloid imaging: from healthy aging to Alzheimer's disease.
Current neurology and neuroscience reports 2009;9(5):345-52.
2009: Sriram Venneti; Brian J Lopresti; Guoji Wang; Ronald L Hamilton; Chester A Mathis; William E Klunk; Udayan M Apte; Clayton A Wiley
PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET.
Neurobiology of aging 2009;30(8):1217-26.
2009: Timo Grimmer; Matthias Riemenschneider; hans förstl; Gjermund Henriksen; William E Klunk; Chester A Mathis; Tohru Shiga; Hans-Jürgen Wester; Alexander Kurz; Alexander Drzezga
Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid.
Biological psychiatry 2009;65(11):927-34.
2009: Oscar L Lopez; J T Becker; A S Wahed; J Saxton; R A Sweet; D A Wolk; William E Klunk; Steven T DeKosky
Long-term effects of the concomitant use of memantine with cholinesterase inhibition in Alzheimer disease.
Journal of neurology, neurosurgery, and psychiatry 2009;80(6):600-7.
2009: David A Wolk; Julie C Price; Judy A Saxton; Beth E Snitz; Jeffrey A James; Oscar L Lopez; Howard J Aizenstein; Ann D Cohen; Lisa A Weissfeld; Chester A Mathis; William E Klunk; Steven T De-Kosky; Steven T DeKoskym
Amyloid imaging in mild cognitive impairment subtypes.
Annals of neurology 2009;65(5):557-68.
2009: Eric Reiman; Kewei Chen; Xiaofen Liu; Daniel Bandy; Meixiang Yu; Wendy Lee; Napatkamon Ayutyanont; Jennifer Keppler; Stephanie A Reeder; Jessica B S Langbaum; Gene Alexander; William E Klunk; Chester A Mathis; Julie C Price; Howard J Aizenstein; Steven T DeKosky; Richard Caselli
Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(16):6820-5.
2009: Kuo-Shyan Lin; Manik L Debnath; Chester A Mathis; William E Klunk
Synthesis and beta-amyloid binding properties of rhenium 2-phenylbenzothiazoles.
Bioorganic & medicinal chemistry letters 2009;19(8):2258-62.
2009: Maria C Carrillo; Andrew Blackwell; Harald Hampel; Johan Lindborg; Reisa Sperling; Dale Schenk; Jeffrey J Sevigny; Steven Ferris; David A Bennett; Suzanne Craft; Timothy Hsu; William E Klunk
Early risk assessment for Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2009;5(2):182-96.
2009: Rebecca L McNamee; Seong-Hwan Yee; Julie C Price; William E Klunk; Bedda Rosario; Lisa A Weissfeld; Scott K Ziolko; Michael Berginc; Brian J Lopresti; Steven T DeKosky; Chester A Mathis
Consideration of optimal time window for Pittsburgh compound B PET summed uptake measurements.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(3):348-55.
2009: Clayton A Wiley; Brian J Lopresti; Sriram Venneti; Julie Price; William E Klunk; Steven T DeKosky; Chester A Mathis
Carbon 11-labeled Pittsburgh Compound B and carbon 11-labeled (R)-PK11195 positron emission tomographic imaging in Alzheimer disease.
Archives of neurology 2009;66(1):60-7.
2008: William E Klunk; Chester A Mathis
The future of amyloid-beta imaging: a tale of radionuclides and tracer proliferation.
Current opinion in neurology 2008;21(6):683-7.
2008: Howard J Aizenstein; Robert D Nebes; Judith A Saxton; Julie C Price; Chester A Mathis; Nicholas D Tsopelas; Scott K Ziolko; Jeffrey A James; Beth E Snitz; Patricia R Houck; Wenzhu Bi; Ann D Cohen; Brian J Lopresti; Steven T DeKosky; Edythe M Halligan; William E Klunk
Frequent amyloid deposition without significant cognitive impairment among the elderly.
Archives of neurology 2008;65(11):1509-17.
2008: William E Klunk
Biopsy support for the validity of Pittsburgh compound B positron emission tomography with a twist.
Archives of neurology 2008;65(10):1281-3.
2008: S N Gomperts; Dorene M Rentz; E Moran; John A Becker; Joseph J Locascio; William E Klunk; Chester A Mathis; David R Elmaleh; T Shoup; Alan J Fischman; Bradley T Hyman; John H Growdon; Keith A Johnson
Imaging amyloid deposition in Lewy body diseases.
Neurology 2008;71(12):903-10.
2008: Jitka Sojkova; Lori L Beason-Held; Yun Zhou; Yang An; Michael A Kraut; Weigo Ye; Luigi Ferrucci; Chester A Mathis; William E Klunk; Dean F Wong; Susan M Resnick
Longitudinal cerebral blood flow and amyloid deposition: an emerging pattern?
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(9):1465-71.
2008: Cyrus A Raji; James Becker; Nicholas D Tsopelas; Julie C Price; Chester A Mathis; Judith A Saxton; Brian J Lopresti; Jessica A Hoge; Scott K Ziolko; Steven T DeKosky; William E Klunk
Characterizing regional correlation, laterality and symmetry of amyloid deposition in mild cognitive impairment and Alzheimer's disease with Pittsburgh Compound B.
Journal of neuroscience methods 2008;172(2):277-82.
2008: William E Klunk; Chester A Mathis
Whatever happened to Pittsburgh Compound-A?
Alzheimer disease and associated disorders 2008;22(3):198-203.
2008: Randall Bateman; William E Klunk
Measuring target effect of proposed disease-modifying therapies in Alzheimer's disease.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2008;5(3):381-90.
2008: Meryl A Butters; William E Klunk; Chester A Mathis; Julie C Price; Scott K Ziolko; Jessica A Hoge; Nicholas D Tsopelas; Brian J Lopresti; Charles F Reynolds; Steven T DeKosky; Carolyn Meltzer
Imaging Alzheimer pathology in late-life depression with PET and Pittsburgh Compound-B.
Alzheimer disease and associated disorders 2008;22(3):261-8.
2008: Milos D Ikonomovic; William E Klunk; Eric Abrahamson; Chester A Mathis; Julie C Price; Nicholas D Tsopelas; Brian J Lopresti; Scott K Ziolko; Wenzhu Bi; William R Paljug; Manik L Debnath; Caroline E Hope; Barbara A Isanski; Ronald L Hamilton; Steven T DeKosky
Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease.
Brain : a journal of neurology 2008;131(Pt 6):1630-45.
2008: Tristan Bolmont; Florent Haiss; Daniel Eicke; Rebecca Radde; Chester A Mathis; William E Klunk; Shinichi Kohsaka; Mathias Jucker; Michael E Calhoun
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(16):4283-92.
2008: Clifford R Jack; Val J. Lowe; Matthew L Senjem; Stephen D Weigand; Brad J Kemp; Maria M Shiung; David S. Knopman; Bradley Boeve; William E Klunk; Chester A Mathis; Ronald C. Petersen
11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment.
Brain : a journal of neurology 2008;131(Pt 3):665-80.
2008: Alexander Drzezga; Timo Grimmer; Gjermund Henriksen; Isabelle Stangier; Robert Perneczky; Janine Diehl-Schmid; Chester A Mathis; William E Klunk; Julie Price; Steven T DeKosky; Hans-Jürgen Wester; Markus Schwaiger; Alexander Kurz
Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease.
NeuroImage 2008;39(2):619-33.
2007: Kerryn E Pike; Greg Savage; Victor L Villemagne; Steven Ng; Simon A Moss; Paul Maruff; Chester A Mathis; William E Klunk; Colin L Masters; Christopher C Rowe
Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease.
Brain : a journal of neurology 2007;130(Pt 11):2837-44.
2007: Chester A Mathis; Brian J Lopresti; William E Klunk
Impact of amyloid imaging on drug development in Alzheimer's disease.
Nuclear medicine and biology 2007;34(7):809-22.
2007: Keith A Johnson; Matt Gregas; John A Becker; Catherine Kinnecom; David H Salat; Erin K Moran; Erin E Smith; Jonathan Rosand; Dorene M Rentz; William E Klunk; Chester A Mathis; Julie C Price; Steven T DeKosky; Alan J Fischman; Steven M Greenberg
Imaging of amyloid burden and distribution in cerebral amyloid angiopathy.
Annals of neurology 2007;62(3):229-34.
2007: William E Klunk; Julie C Price; Chester A Mathis; Nicholas D Tsopelas; Brian J Lopresti; Scott K Ziolko; Wenzhu Bi; Jessica A Hoge; Ann D Cohen; Milos D Ikonomovic; Judith A Saxton; Beth E Snitz; Daniel A Pollen; Majaz Moonis; Carol F Lippa; Joan M Swearer; Keith A Johnson; Dorene M Rentz; Alan J Fischman; Howard J Aizenstein; Steven T DeKosky
Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(23):6174-84.
2007: Yun Zhou; Susan M Resnick; Weiguo Ye; Hong Fan; Daniel P Holt; William E Klunk; Chester A Mathis; Robert F Dannals; Dean F Wong
Using a reference tissue model with spatial constraint to quantify [11C]Pittsburgh compound B PET for early diagnosis of Alzheimer's disease.
NeuroImage 2007;36(2):298-312.
2007: Christopher C Rowe; Steven Ng; U Ackermann; Sylvia J Gong; K Pike; G Savage; T F Cowie; K L Dickinson; Paul Maruff; D Darby; C Smith; M Woodward; John R Merory; Henri Tochon-Danguy; Graeme J O'Keefe; William E Klunk; Chester A Mathis; J C Price; Colin L Masters; Victor L Villemagne
Imaging beta-amyloid burden in aging and dementia.
Neurology 2007;68(20):1718-25.
2007: Gil Rabinovici; A J Furst; James P O'Neil; C A Racine; E C Mormino; S L Baker; S Chetty; P Patel; T A Pagliaro; William E Klunk; C A Mathis; Howard J Rosen; Bruce L Miller; William J Jagust
11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration.
Neurology 2007;68(15):1205-12.
2007: Brian J Bacskai; Matthew P Frosch; Stefanie H Freeman; Scott B Raymond; Jean C Augustinack; Keith A Johnson; Michael C Irizarry; William E Klunk; Chester A Mathis; Steven T DeKosky; Steven M Greenberg; Bradley T Hyman; John H Growdon
Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report.
Archives of neurology 2007;64(3):431-4.
2006: William E Klunk; Chester A Mathis; Julie C Price; Brian J Lopresti; Steven T DeKosky
Two-year follow-up of amyloid deposition in patients with Alzheimer's disease.
Brain : a journal of neurology 2006;129(Pt 11):2805-7.
2006: Scott K Ziolko; Lisa A Weissfeld; William E Klunk; Chester A Mathis; Jessica A Hoge; Brian J Lopresti; Steven T DeKosky; Julie C Price
Evaluation of voxel-based methods for the statistical analysis of PIB PET amyloid imaging studies in Alzheimer's disease.
NeuroImage 2006;33(1):94-102.
2006: Mark A Mintun; Gina N LaRossa; Yvette I Sheline; Carmen S Dence; S Y Lee; Robert H Mach; William E Klunk; Chester A Mathis; Steven T DeKosky; John C Morris
[11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease.
Neurology 2006;67(3):446-52.
2006: Bruno Stankoff; Yanming Wang; Michel Bottlaender; Marie-Stéphane Aigrot; Frederic Dolle; Chunying Wu; Douglas L Feinstein; Guo-Feng Huang; Franck Semah; Chester A Mathis; William E Klunk; Robert Gould; Catherine Lubetzki; Bernard Zalc
Imaging of CNS myelin by positron-emission tomography.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9304-9.
2006: Mony J de Leon; William E Klunk
Biomarkers for the early diagnosis of Alzheimer's disease.
Lancet neurology 2006;5(3):198-9.
2006: Anne M Fagan; Mark A Mintun; Robert H Mach; Sang-Yoon Lee; Carmen S Dence; Aarti R Shah; Gina N LaRossa; Michael L Spinner; William E Klunk; Chester A Mathis; Steven T DeKosky; John C Morris; David M Holtzman
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.
Annals of neurology 2006;59(3):512-9.
2006: Milos D Ikonomovic; Eric Abrahamson; Barbara A Isanski; Manik L Debnath; Chester A Mathis; Steven T DeKosky; William E Klunk
X-34 labeling of abnormal protein aggregates during the progression of Alzheimer's disease.
Methods in enzymology 2006;412():123-44.
2006: Leon J Thal; Kejal Kantarci; Eric Reiman; William E Klunk; Michael Weiner; Henrik Zetterberg; Douglas Galasko; Domenico Pratico'; Sue Griffin; Dale Schenk; Eric Siemers
The role of biomarkers in clinical trials for Alzheimer disease.
Alzheimer disease and associated disorders 2006;20(1):6-15.
2005: Brian J Lopresti; William E Klunk; Chester A Mathis; Jessica A Hoge; Scott K Ziolko; Xueling Lu; Carolyn Meltzer; Kurt Schimmel; Nicholas D Tsopelas; Steven T DeKosky; Julie C Price
Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(12):1959-72.
2005: William E Klunk; Brian J Lopresti; Milos D Ikonomovic; Iliya Lefterov; Radosveta P Koldamova; Eric Abrahamson; Manik L Debnath; Daniel P Holt; Guo-Feng Huang; Li Shao; Steven T DeKosky; Julie C Price; Chester A Mathis
Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(46):10598-606.
2005: Julie C Price; William E Klunk; Brian J Lopresti; Xueling Lu; Jessica A Hoge; Scott K Ziolko; Daniel P Holt; Carolyn Meltzer; Steven T DeKosky; Chester A Mathis
Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(11):1528-47.
2005: Purnima P Desai; Milos D Ikonomovic; Eric Abrahamson; Ronald L Hamilton; Barbara A Isanski; Caroline E Hope; William E Klunk; Steven T DeKosky; M Ilyas Kamboh
Apolipoprotein D is a component of compact but not diffuse amyloid-beta plaques in Alzheimer's disease temporal cortex.
Neurobiology of disease 2005;20(2):574-82.
2005: John C Morris; A Kimberly; K Quaid; David M Holtzman; Kejal Kantarci; Jeffrey A Kaye; Eric Reiman; William E Klunk; Eric R Siemers
Role of biomarkers in studies of presymptomatic Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2005;1(2):145-51.
2005: William E Klunk
Commentary on "Diagnosis of Alzheimer's disease: two decades of progress." Diagnosis of Alzheimer's disease: walking a well-paved path.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2005;1(2):99-100.
2005: Evgueni E Nesterov; Jesse Skoch; Bradley T Hyman; William E Klunk; Brian J Bacskai; Timothy M Swager
In vivo optical imaging of amyloid aggregates in brain: design of fluorescent markers.
Angewandte Chemie (International ed. in English) 2005;44(34):5452-6.
2005: Randy L Buckner; Abraham Z Snyder; Benjamin J Shannon; Gina N LaRossa; Rimmon Sachs; Anthony F Fotenos; Yvette I Sheline; William E Klunk; Chester A Mathis; John C Morris; Mark A Mintun
Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(34):7709-17.
2005: Yasuji Matsuoka; Li Shao; Manik Debnath; John LaFrancois; Amanda Becker; Audrey Gray; Paul S Aisen; Chester Mathis; William E Klunk; karen duff
An Abeta sequestration approach using non-antibody Abeta binding agents.
Current Alzheimer research 2005;2(2):265-8.
2005: Chester A Mathis; William E Klunk; Julie C Price; Steven T DeKosky
Imaging technology for neurodegenerative diseases: progress toward detection of specific pathologies.
Archives of neurology 2005;62(2):196-200.
2005: Robert P Brendza; Brian J Bacskai; John R Cirrito; Kelly Simmons; Jesse Skoch; William E Klunk; Chester A Mathis; Kelly R Bales; Steven M Paul; Bradley T Hyman; David M Holtzman
Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice.
The Journal of clinical investigation 2005;115(2):428-33.
2005: Oscar L Lopez; James Becker; Judith Saxton; Robert A Sweet; William E Klunk; Steven T DeKosky
Alteration of a clinically meaningful outcome in the natural history of Alzheimer's disease by cholinesterase inhibition.
Journal of the American Geriatrics Society 2005;53(1):83-7.
2004: Martin Sadowski; Joanna Pankiewicz; Henrieta Scholtzova; Julia Tsai; Yongsheng Li; Richard I Carp; Harry C Meeker; Pierluigi Gambetti; Manik L Debnath; Chester A Mathis; Li Shao; Wen-Biao Gan; William E Klunk; Thomas Wisniewski
Targeting prion amyloid deposits in vivo.
Journal of neuropathology and experimental neurology 2004;63(7):775-84.
2004: William E Klunk; Henry Willy Engler; agneta nordberg; Yanming Wang; Gunnar Blomqvist; Daniel P Holt; Mats Bergström; Irina Savitcheva; Guo-Feng Huang; Sergio Estrada; Birgitta Ausén; Manik L Debnath; Julien Barletta; Julie C Price; Johan Sandell; Brian J Lopresti; Anders Wall; Pernilla Koivisto; Gunnar Antoni; Chester A Mathis; Bengt Långström
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B.
Annals of neurology 2004;55(3):306-19.
2004: Yanming Wang; William E Klunk; Manik L Debnath; Guo-Feng Huang; Daniel P Holt; Li Shao; Chester A Mathis
Development of a PET/SPECT agent for amyloid imaging in Alzheimer's disease.
Journal of molecular neuroscience : MN 2004;24(1):55-62.
2004: Chester A Mathis; Yanming Wang; William E Klunk
Imaging beta-amyloid plaques and neurofibrillary tangles in the aging human brain.
Current pharmaceutical design 2004;10(13):1469-92.
2003: William E Klunk; Henry Willy Engler; agneta nordberg; Brian J Bacskai; Yanming Wang; Julie C Price; Mats Bergström; Bradley T Hyman; Bengt Långström; Chester A Mathis
Imaging the pathology of Alzheimer's disease: amyloid-imaging with positron emission tomography.
Neuroimaging clinics of North America 2003;13(4):781-9, ix.
2003: Jaroslaw Kanski; Rukhsana Sultana; William E Klunk; D Allan Butterfield
Antioxidant activity of X-34 in synaptosomal and neuronal systems.
Brain research 2003;988(1-2):173-9.
2003: Brian J Bacskai; Gregory A Hickey; Jesse Skoch; Stephen T Kajdasz; Yanming Wang; Guo-Feng Huang; Chester A Mathis; William E Klunk; Bradley T Hyman
Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-beta ligand in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):12462-7.
2003: Chester A Mathis; Yanming Wang; Daniel P Holt; Guo-Feng Huang; Manik L Debnath; William E Klunk
Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents.
Journal of medicinal chemistry 2003;46(13):2740-54.
2003: William E Klunk; Yanming Wang; Guo-Feng Huang; Manik L Debnath; Daniel P Holt; Li Shao; Ronald L Hamilton; Milos D Ikonomovic; Steven T DeKosky; Chester A Mathis
The binding of 2-(4'-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(6):2086-92.
2003: Yanming Wang; Chester A Mathis; Guo-Feng Huang; Manik L Debnath; Daniel P Holt; Li Shao; William E Klunk
Effects of lipophilicity on the affinity and nonspecific binding of iodinated benzothiazole derivatives.
Journal of molecular neuroscience : MN 2003;20(3):255-60.
2003: Oscar L Lopez; James Becker; Robert A Sweet; William E Klunk; Daniel Kaufer; Judith Saxton; Miguel E Habeych; Steven T DeKosky
Psychiatric symptoms vary with the severity of dementia in probable Alzheimer's disease.
The Journal of neuropsychiatry and clinical neurosciences 2003;15(3):346-53.
2003: Oscar L Lopez; James Becker; Robert A Sweet; William E Klunk; Daniel Kaufer; Judith Saxton; Steven T DeKosky
Patterns of change in the treatment of psychiatric symptoms in patients with probable Alzheimer's disease from 1983 to 2000.
The Journal of neuropsychiatry and clinical neurosciences 2003;15(1):67-73.
2003: Steven T DeKosky; Milos D Ikonomovic; Xiaoyan Wang; Martin R Farlow; Stephen R Wisniewski; Oscar L Lopez; James Becker; Judith Saxton; William E Klunk; Robert Sweet; Daniel Kaufer; M Ilyas Kamboh
Plasma and cerebrospinal fluid alpha1-antichymotrypsin levels in Alzheimer's disease: correlation with cognitive impairment.
Annals of neurology 2003;53(1):81-90.
2002: Kazuhiro Ishii; William E Klunk; Shigeki Arawaka; Manik L Debnath; Yoshiko Furiya; Naruhiko Sahara; Shin'ichi Shoji; Akira Tamaoka; Jay W Pettegrew; Hiroshi Mori
Chrysamine G and its derivative reduce amyloid beta-induced neurotoxicity in mice.
Neuroscience letters 2002;333(1):5-8.
2002: William E Klunk; Brian J Bacskai; Chester A Mathis; Stephen T Kajdasz; Megan E McLellan; Matthew P Frosch; Manik L Debnath; Daniel P Holt; Yanming Wang; Bradley T Hyman
Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative.
Journal of neuropathology and experimental neurology 2002;61(9):797-805.
2002: Brian J Bacskai; William E Klunk; Chester A Mathis; Bradley T Hyman
Imaging amyloid-beta deposits in vivo.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(9):1035-41.
2002: Yanming Wang; William E Klunk; Guo-Feng Huang; Manik L Debnath; Daniel P Holt; Chester A Mathis
Synthesis and evaluation of 2-(3'-iodo-4'-aminophenyl)-6-hydroxybenzothiazole for in vivo quantitation of amyloid deposits in Alzheimer's disease.
Journal of molecular neuroscience : MN 2002;19(1-2):11-6.
2002: Robert A Sweet; Kanagasabai Panchalingam; Jay W Pettegrew; Richard J McClure; Ronald L Hamilton; Oscar L Lopez; Daniel Kaufer; Steven T DeKosky; William E Klunk
Psychosis in Alzheimer disease: postmortem magnetic resonance spectroscopy evidence of excess neuronal and membrane phospholipid pathology.
Neurobiology of aging 2002;23(4):547-53.
2002: William E Klunk
Blood and CSF biomarkers for AD revisited: what's new, what's good, and is this where we should be looking?
Neurobiology of aging 2002;23(4):517-9; discussion 521-2.
2002: Ellen M Whyte; Benoit H Mulsant; Meryl A Butters; Moshin Qayyum; Adele L Towers; Robert A Sweet; William E Klunk; Steve Wisniewski; Steven T DeKosky
Cognitive and behavioral correlates of low vitamin B12 levels in elderly patients with progressive dementia.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2002;10(3):321-7.
2002: Chester A Mathis; Brian J Bacskai; Stephen T Kajdasz; Megan E McLellan; Matthew P Frosch; Bradley T Hyman; Daniel P Holt; Yanming Wang; Guo-Feng Huang; Manik L Debnath; William E Klunk
A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain.
Bioorganic & medicinal chemistry letters 2002;12(3):295-8.
2002: Robert A Sweet; M Ilyas Kamboh; Stephen R Wisniewski; Oscar L Lopez; William E Klunk; Daniel Kaufer; Steven T DeKosky
Apolipoprotein E and alpha-1-antichymotrypsin genotypes do not predict time to psychosis in Alzheimer's disease.
Journal of geriatric psychiatry and neurology 2002;15(1):24-30.
2002: Oscar L Lopez; James Becker; Daniel Kaufer; Ronald L Hamilton; Robert A Sweet; William E Klunk; Steven T DeKosky
Research evaluation and prospective diagnosis of dementia with Lewy bodies.
Archives of neurology 2002;59(1):43-6.
2001: Robert A Sweet; Bruce G Pollock; DL Sukonick; Benoit H Mulsant; Jules Rosen; William E Klunk; Kari B Kastango; Steven T DeKosky; Robert E Ferrell
The 5-HTTPR polymorphism confers liability to a combined phenotype of psychotic and aggressive behavior in Alzheimer disease.
International psychogeriatrics / IPA 2001;13(4):401-9.
2001: Donna L Smith; R Portier; Ben Woodman; Emma Hockly; Amarbirpal Mahal; William E Klunk; Xiao-Jiang Li; Erich E Wanker; Karl D Murray; Gillian P Bates
Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles.
Neurobiology of disease 2001;8(6):1017-26.
2001: DL Sukonick; Bruce G Pollock; Robert A Sweet; Benoit H Mulsant; Jules Rosen; William E Klunk; Kari B Kastango; Steven T DeKosky; Robert E Ferrell
The 5-HTTPR*S/*L polymorphism and aggressive behavior in Alzheimer disease.
Archives of neurology 2001;58(9):1425-8.
2001: William E Klunk; Yanming Wang; Guo-Feng Huang; Manik L Debnath; Daniel P Holt; Chester A Mathis
Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain.
Life sciences 2001;69(13):1471-84.
2001: Christopher D Link; Carolyn J Johnson; Virginia Fonte; Marie C Paupard; David H Hall; Scot D Styren; C A Mathis; William E Klunk
Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34.
Neurobiology of aging 2001;22(2):217-26.
2000: Oscar L Lopez; James Becker; William E Klunk; Judith Saxton; Ronald L Hamilton; Daniel Kaufer; Robert A Sweet; Carolyn Cidis Meltzer; Stephen R Wisniewski; M Ilyas Kamboh; Steven T DeKosky
Research evaluation and diagnosis of possible Alzheimer's disease over the last two decades: II.
Neurology 2000;55(12):1863-9.
2000: Oscar L Lopez; James Becker; William E Klunk; Judith Saxton; Ronald L Hamilton; Daniel Kaufer; Robert A Sweet; Carolyn Cidis Meltzer; Stephen R Wisniewski; M Ilyas Kamboh; Steven T DeKosky
Research evaluation and diagnosis of probable Alzheimer's disease over the last two decades: I.
Neurology 2000;55(12):1854-62.
2000: Robert A Sweet; Ronald L Hamilton; Oscar L Lopez; William E Klunk; Stephen R Wisniewski; Daniel Kaufer; M T Healy; Steven T DeKosky
Psychotic symptoms in Alzheimer's disease are not associated with more severe neuropathologic features.
International psychogeriatrics / IPA 2000;12(4):547-58.
2000: Jay W Pettegrew; William E Klunk; Kanagasabai Panchalingam; Richard J McClure; Jeffrey Stanley
Molecular insights into neurodevelopmental and neurodegenerative diseases.
Brain research bulletin 2000;53(4):455-69.
2000: Scot D Styren; Ronald L Hamilton; G C Styren; William E Klunk
X-34, a fluorescent derivative of Congo red: a novel histochemical stain for Alzheimer's disease pathology.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000;48(9):1223-32.
1999: Oscar L Lopez; I Litvan; K E Catt; R Stowe; William E Klunk; Daniel Kaufer; James Becker; Steven T DeKosky
Accuracy of four clinical diagnostic criteria for the diagnosis of neurodegenerative dementias.
Neurology 1999;53(6):1292-9.
1999: William E Klunk; Robert Jacob; R P Mason
Quantifying amyloid by congo red spectral shift assay.
Methods in enzymology 1999;309():285-305.
1999: William E Klunk; Robert Jacob; R P Mason
Quantifying amyloid beta-peptide (Abeta) aggregation using the Congo red-Abeta (CR-abeta) spectrophotometric assay.
Analytical biochemistry 1999;266(1):66-76.
1998: William E Klunk; Kanagasabai Panchalingam; Richard J McClure; Jeffrey Stanley; Jay W Pettegrew
Metabolic alterations in postmortem Alzheimer's disease brain are exaggerated by Apo-E4.
Neurobiology of aging 1998;19(6):511-5.
1998: William E Klunk
Biological markers of Alzheimer's disease.
Neurobiology of aging 1998;19(2):145-7.
1998: William E Klunk; Manik L Debnath; A M Koros; Jay W Pettegrew
Chrysamine-G, a lipophilic analogue of Congo red, inhibits A beta-induced toxicity in PC12 cells.
Life sciences 1998;63(20):1807-14.
1997: Jay W Pettegrew; William E Klunk; Kanagasabai Panchalingam; Richard J McClure; Jeffrey Stanley
Magnetic resonance spectroscopic changes in Alzheimer's disease.
Annals of the New York Academy of Sciences 1997;826():282-306.
1997: C J Xu; J N Kanfer; William E Klunk; Q Xiong; Richard J McClure; Jay W Pettegrew
Effect of phosphomonoesters, phosphodiesters, and phosphocreatine on glutamate uptake by synaptic vesicles.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1997;32(1-3):89-99.
1997: William E Klunk; C J Xu; Richard J McClure; Kanagasabai Panchalingam; Jeffrey Stanley; Jay W Pettegrew
Aggregation of beta-amyloid peptide is promoted by membrane phospholipid metabolites elevated in Alzheimer's disease brain.
Journal of neurochemistry 1997;69(1):266-72.
1996: C J Xu; William E Klunk; J N Kanfer; Q Xiong; G Miller; Jay W Pettegrew
Phosphocreatine-dependent glutamate uptake by synaptic vesicles. A comparison with atp-dependent glutamate uptake.
The Journal of biological chemistry 1996;271(23):13435-40.
1996: William E Klunk; C Xu; Kanagasabai Panchalingam; Richard J McClure; Jay W Pettegrew
Quantitative 1H and 31P MRS of PCA extracts of postmortem Alzheimer's disease brain.
Neurobiology of aging 1996;17(3):349-57.
1995: Jay W Pettegrew; William E Klunk; E Kanal; Kanagasabai Panchalingam; Richard J McClure
Changes in brain membrane phospholipid and high-energy phosphate metabolism precede dementia.
Neurobiology of aging 1995;16(6):973-5.
1995: William E Klunk; Richard J McClure; C J Xu; Jay W Pettegrew
Structural determinants of activity at the GABAB receptor. A comparison of phosphoethanolamine and related GABA analogs.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1995;26(1):15-30.
1995: William E Klunk; M L Debnath; Jay W Pettegrew
Chrysamine-G binding to Alzheimer and control brain: autopsy study of a new amyloid probe.
Neurobiology of aging 1995;16(4):541-8.
1995: Richard J McClure; J N Kanfer; Kanagasabai Panchalingam; William E Klunk; Jay W Pettegrew
Magnetic resonance spectroscopy and its application to aging and Alzheimer's disease.
Neuroimaging clinics of North America 1995;5(1):69-86.
1995: William E Klunk; M L Debnath; Richard J McClure; Jay W Pettegrew
Inactivity of phosphoethanolamine, an endogenous GABA analog decreased in Alzheimer's disease, at GABA binding sites.
Life sciences 1995;56(26):2377-83.
1995: Jay W Pettegrew; William E Klunk; Kanagasabai Panchalingam; J N Kanfer; Richard J McClure
Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer's disease.
Neurobiology of aging 1995;16(1):1-4.
1994: Richard J McClure; J N Kanfer; Kanagasabai Panchalingam; William E Klunk; Jay W Pettegrew
Alzheimer's disease: membrane-associated metabolic changes.
Annals of the New York Academy of Sciences 1994;747():110-24.
1994: William E Klunk; M L Debnath; Jay W Pettegrew
Development of small molecule probes for the beta-amyloid protein of Alzheimer's disease.
Neurobiology of aging 1994;15(6):691-8.
1994: Oscar L Lopez; M R Larumbe; James Becker; D Rezek; Jules Rosen; William E Klunk; Steven T DeKosky
Reliability of NINDS-AIREN clinical criteria for the diagnosis of vascular dementia.
Neurology 1994;44(7):1240-5.
1994: William E Klunk; C J Xu; Jay W Pettegrew
NMR identification of the formic acid-modified residue in Alzheimer's amyloid protein.
Journal of neurochemistry 1994;62(1):349-54.
1994: William E Klunk; C J Xu; Kanagasabai Panchalingam; Richard J McClure; Jay W Pettegrew
Analysis of magnetic resonance spectra by mole percent: comparison to absolute units.
Neurobiology of aging 1994;15(1):133-40.
1994: Jay W Pettegrew; Kanagasabai Panchalingam; William E Klunk; Richard J McClure; L R Muenz
Alterations of cerebral metabolism in probable Alzheimer's disease: a preliminary study.
Neurobiology of aging 1994;15(1):117-32.
1992: William E Klunk; Kanagasabai Panchalingam; J Moossy; Richard J McClure; Jay W Pettegrew
N-acetyl-L-aspartate and other amino acid metabolites in Alzheimer's disease brain: a preliminary proton nuclear magnetic resonance study.
Neurology 1992;42(8):1578-85.
1991: William E Klunk; Richard J McClure; Jay W Pettegrew
Possible roles of L-phosphoserine in the pathogenesis of Alzheimer's disease.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1991;15(1):51-73.
1991: William E Klunk; Richard J McClure; Jay W Pettegrew
L-phosphoserine, a metabolite elevated in Alzheimer's disease, interacts with specific L-glutamate receptor subtypes.
Journal of neurochemistry 1991;56(6):1997-2003.
1990: William E Klunk; Jay W Pettegrew
Alzheimer's beta-amyloid protein is covalently modified when dissolved in formic acid.
Journal of neurochemistry 1990;54(6):2050-6.
1989: William E Klunk; Jay W Pettegrew; D J Abraham
Two simple methods for quantifying low-affinity dye-substrate binding.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1989;37(8):1293-7.
1989: William E Klunk; Jay W Pettegrew; D J Abraham
Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1989;37(8):1273-81.
1988: William E Klunk; D J Abraham
Filamentous proteins in Alzheimer's disease: new insights through molecular biology.
Psychiatric developments 1988;6(2):121-52.
1983: James A Ferrendelli; A C McKeon; William E Klunk
Effects of alkyl-substituted gamma-butyrolactones and succinimides on the evoked and spontaneous activity of hippocampal slices in vitro.
Experimental neurology 1983;82(3):663-74.
1983: William E Klunk; Douglas F Covey; James A Ferrendelli
Alkyl-substituted gamma-butyrolactones as potential tools in the study and treatment of epilepsy.
Biochemical pharmacology 1983;32(20):2999-3004.
1983: William E Klunk; B L Kalman; James A Ferrendelli; Douglas F Covey
Computer-assisted modeling of the picrotoxinin and gamma-butyrolactone receptor site.
Molecular pharmacology 1983;23(2):511-8.
1982: William E Klunk; A McKeon; Douglas F Covey; James A Ferrendelli
Alpha-substituted gamma-butyrolactones: new class of anticonvulsant drugs.
Science (New York, N.Y.) 1982;217(4564):1040-2.
1982: William E Klunk; Douglas F Covey; James A Ferrendelli
Structure-activity relationships of alkyl-substituted gamma-butyrolactones and succinimides.
Molecular pharmacology 1982;22(2):444-50.
1982: William E Klunk; Douglas F Covey; James A Ferrendelli
Anticonvulsant properties of alpha, gamma, and alpha, gamma-substituted gamma-butyrolactones.
Molecular pharmacology 1982;22(2):438-43.
1982: William E Klunk; Douglas F Covey; James A Ferrendelli
Comparison of epileptogenic properties of unsubstituted and beta-alkyl-substituted gamma-butyrolactones.
Molecular pharmacology 1982;22(2):431-7.