FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Ad Knaapen

Research Profile

Disorders

Anatomy

Chemicals & Drugs

Living Beings

Rats

Procedures

Concepts & Ideas

Particle Size

Physiology

DNA Repair

Co-author Network

Publications

TOP 3
Hans B Ketelslegers; Jos C S Kleinjans; Ad M Knaapen; Gudrun Koppen; Vera Nelen; Greet Schoeters; Joost H M van Delft; Willy F Baeyens; Joep P M Geraedts; Roger W L Godschalk; Ralph W H Gottschalk; Nicolas van Larebeke
Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study.
Damien van Berlo; Catrin Albrecht; Ad M Knaapen; Flemming R Cassee; Miriam E Gerlofs-Nijland; Ingeborg M Kooter; Nicola Palomero-Gallagher; Hans-J Bidmon; Frederik-Jan van Schooten; Jean Krutmann; Roel P F Schins
Comparative evaluation of the effects of short-term inhalation exposure to diesel engine exhaust on rat lung and brain.
Nejla Güngör; Ad M Knaapen; Armelle Munnia; Marco Peluso; Guido R Haenen; Roland K Chiu; Roger Godschalk; Frederik J Van Schooten
Genotoxic effects of neutrophils and hypochlorous acid.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Ad Knaapen (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: Hans B Ketelslegers; Jos C S Kleinjans; Ad M Knaapen; Gudrun Koppen; Vera Nelen; Greet Schoeters; Joost H M van Delft; Willy F Baeyens; Joep P M Geraedts; Roger W L Godschalk; Ralph W H Gottschalk; Nicolas van Larebeke
Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study.
Environmental health : a global access science source 2011;10():85.
2010: Damien van Berlo; Catrin Albrecht; Ad M Knaapen; Flemming R Cassee; Miriam E Gerlofs-Nijland; Ingeborg M Kooter; Nicola Palomero-Gallagher; Hans-J Bidmon; Frederik-Jan van Schooten; Jean Krutmann; Roel P F Schins
Comparative evaluation of the effects of short-term inhalation exposure to diesel engine exhaust on rat lung and brain.
Archives of toxicology 2010;84(7):553-62.
2010: Nejla Güngör; Ad M Knaapen; Armelle Munnia; Marco Peluso; Guido R Haenen; Roland K Chiu; Roger Godschalk; Frederik J Van Schooten
Genotoxic effects of neutrophils and hypochlorous acid.
Mutagenesis 2010;25(2):149-54.
2010: Ingeborg M Kooter; Miriam E Gerlofs-Nijland; john boere; Daan L A C Leseman; Paul H B Fokkens; Henri M H Spronk; Kim Frederix; Hugo ten Cate; Ad M Knaapen; Hendrik J Vreman; Flemming R Cassee
Diesel engine exhaust initiates a sequence of pulmonary and cardiovascular effects in rats.
Journal of toxicology 2010;2010():206057.
2010: Damien van Berlo; Ad M Knaapen; Frederik J Van Schooten; Roel P F Schins; Catrin Albrecht
NF-kappaB dependent and independent mechanisms of quartz-induced proinflammatory activation of lung epithelial cells.
Particle and fibre toxicology 2010;7():13.
2010: Nejla Güngör; Jeroen L A Pennings; Ad M Knaapen; Roland K Chiu; Marco Peluso; Roger Godschalk; Frederik J Van Schooten
Transcriptional profiling of the acute pulmonary inflammatory response induced by LPS: role of neutrophils.
Respiratory research 2010;11():24.
2010: Nejla Güngör; Astrid Haegens; Ad M Knaapen; Roger Godschalk; Roland K Chiu; Emiel F M Wouters; Frederik J Van Schooten
Lung inflammation is associated with reduced pulmonary nucleotide excision repair in vivo.
Mutagenesis 2010;25(1):77-82.
2009: Marieke Quaak; Constant P van Schayck; Ad M Knaapen; Frederik J Van Schooten
Implications of gene-drug interactions in smoking cessation for improving the prevention of chronic degenerative diseases.
Mutation research 2009;667(1-2):44-57.
2009: M Quaak; Constant P van Schayck; Ad M Knaapen; F J van Schooten
Genetic variation as a predictor of smoking cessation success. A promising preventive and intervention tool for chronic respiratory diseases?
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;33(3):468-80.
2009: Yvonne G J van Helden; Jaap Keijer; Ad M Knaapen; Sandra G Heil; Jacob J Briedé; Frederik J Van Schooten; Roger Godschalk
Beta-carotene metabolites enhance inflammation-induced oxidative DNA damage in lung epithelial cells.
Free radical biology & medicine 2009;46(2):299-304.
2008: Hui Li; Damien van Berlo; Tingming Shi; Günter Speit; Ad M Knaapen; Paul J A Borm; Catrin Albrecht; Roel P F Schins
Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line.
Toxicology and applied pharmacology 2008;227(1):115-24.
2007: Nejla Güngör; Roger Godschalk; Daniëlle M F A Pachen; Frederik J Van Schooten; Ad M Knaapen
Activated neutrophils inhibit nucleotide excision repair in human pulmonary epithelial cells: role of myeloperoxidase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(10):2359-67.
2007: Frederik J Van Schooten; Ad M Knaapen; Alberto Izzotti
DNA damage, mutagenesis and cardiovascular disease.
Mutation research 2007;621(1-2):1-4.
2007: Ad M Knaapen; Daniëlle M J Curfs; Daniëlle M F A Pachen; Ralph W H Gottschalk; Menno de Winther; Mat J A P Daemen; Frederik J Van Schooten
The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis.
Mutation research 2007;621(1-2):31-41.
2007: Simone G J van Breda; Janneke G F Hogervorst; Leo J Schouten; Ad M Knaapen; Joost H M van Delft; R Alexandra Goldbohm; Frederik J Van Schooten; Piet A van den Brandt
Toenails: an easily accessible and long-term stable source of DNA for genetic analyses in large-scale epidemiological studies.
Clinical chemistry 2007;53(6):1168-70.
2007: Sabine A S Langie; Ad M Knaapen; Chantal H M A Ramaekers; Jan Theys; Jan Brun; Roger Godschalk; Frederik J Van Schooten; Philippe Lambin; Douglas A Gray; Bradly G Wouters; Roland K Chiu
Formation of lysine 63-linked poly-ubiquitin chains protects human lung cells against benzo[a]pyrene-diol-epoxide-induced mutagenicity.
DNA repair 2007;6(6):852-62.
2007: Hui Li; Petra Haberzettl; Catrin Albrecht; Doris Höhr; Ad M Knaapen; Paul J A Borm; Roel P F Schins
Inhibition of the mitochondrial respiratory chain function abrogates quartz induced DNA damage in lung epithelial cells.
Mutation research 2007;617(1-2):46-57.
2007: Sabine A S Langie; Ad M Knaapen; Joyce M J Houben; Frederik C van Kempen; Joep P J de Hoon; Ralph W H Gottschalk; Roger Godschalk; Frederik J Van Schooten
The role of glutathione in the regulation of nucleotide excision repair during oxidative stress.
Toxicology letters 2007;168(3):302-9.
2007: Roel P F Schins; Ad M Knaapen
Genotoxicity of poorly soluble particles.
Inhalation toxicology 2007;19 Suppl 1():189-98.
2006: Ad M Knaapen; Nejla Güngör; Roel P F Schins; Paul J A Borm; Frederik J Van Schooten
Neutrophils and respiratory tract DNA damage and mutagenesis: a review.
Mutagenesis 2006;21(4):225-36.
2006: Andrea Becker; Catrin Albrecht; Ad M Knaapen; Roel P F Schins; Doris Höhr; Kirstin Ledermann; Paul J A Borm
Induction of CYP1A1 in rat lung cells following in vivo and in vitro exposure to quartz.
Archives of toxicology 2006;80(5):258-68.
2006: Hans B Ketelslegers; Ralph W H Gottschalk; Roger Godschalk; Ad M Knaapen; Frederik J Van Schooten; Robert Francois Vlietinck; Jos C S Kleinjans; Joost H M van Delft
Interindividual variations in DNA adduct levels assessed by analysis of multiple genetic polymorphisms in smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(4):624-9.
2006: Sabine A S Langie; Ad M Knaapen; Karen J J Brauers; Damien van Berlo; Frederik J Van Schooten; Roger Godschalk
Development and validation of a modified comet assay to phenotypically assess nucleotide excision repair.
Mutagenesis 2006;21(2):153-8.
2005: Ad M Knaapen; Roel P F Schins; Paul J A Borm; Frederik J Van Schooten
Nitrite enhances neutrophil-induced DNA strand breakage in pulmonary epithelial cells by inhibition of myeloperoxidase.
Carcinogenesis 2005;26(9):1642-8.
2005: Daniëlle M J Curfs; Ad M Knaapen; Daniëlle M F A Pachen; Marion J J Gijbels; Esther Lutgens; Marjan Smook; Mark M Kockx; Mat J A P Daemen; Frederik J Van Schooten
Polycyclic aromatic hydrocarbons induce an inflammatory atherosclerotic plaque phenotype irrespective of their DNA binding properties.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1290-2.
2005: Catrin Albrecht; Ad M Knaapen; Andrea Becker; Doris Höhr; Petra Haberzettl; Frederik J Van Schooten; Paul J A Borm; Roel P F Schins
The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung.
Respiratory research 2005;6():129.
2004: Ad M Knaapen; Hans B Ketelslegers; Ralph W H Gottschalk; Rob G J H Janssen; Aimée D C Paulussen; H J M Smeets; Roger Godschalk; Frederik J Van Schooten; Jos C S Kleinjans; Joost H M van Delft
Simultaneous genotyping of nine polymorphisms in xenobiotic-metabolizing enzymes by multiplex PCR amplification and single base extension.
Clinical chemistry 2004;50(9):1664-8.
2004: Catrin Albrecht; Roel P F Schins; Doris Höhr; Andrea Becker; Tingming Shi; Ad M Knaapen; Paul J A Borm
Inflammatory time course after quartz instillation: role of tumor necrosis factor-alpha and particle surface.
American journal of respiratory cell and molecular biology 2004;31(3):292-301.
2004: Ad M Knaapen; Paul J A Borm; Catrin Albrecht; Roel P F Schins
Inhaled particles and lung cancer. Part A: Mechanisms.
International journal of cancer. Journal international du cancer 2004;109(6):799-809.
2004: Frederik J Van Schooten; Agnes W Boots; Ad M Knaapen; Roger Godschalk; Lou M Maas; Paul J A Borm; Marjolein Drent; Jan A Jacobs
Myeloperoxidase (MPO) -463G->A reduces MPO activity and DNA adduct levels in bronchoalveolar lavages of smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(5):828-33.
2003: Tingming Shi; Roel P F Schins; Ad M Knaapen; Thomas Kuhlbusch; Mike Pitz; Joachim Heinrich; Paul J A Borm
Hydroxyl radical generation by electron paramagnetic resonance as a new method to monitor ambient particulate matter composition.
Journal of environmental monitoring : JEM 2003;5(4):550-6.
2003: Ken Donaldson; Vicki Stone; Paul J A Borm; Luis A Jimenez; Peter S Gilmour; Roel P F Schins; Ad M Knaapen; Irfan Rahman; Stephen P Faux; David M Brown; William MacNee
Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10).
Free radical biology & medicine 2003;34(11):1369-82.
2003: Tingming Shi; Ad M Knaapen; Jutta Begerow; W Birmili; Paul J A Borm; Roel P F Schins
Temporal variation of hydroxyl radical generation and 8-hydroxy-2'-deoxyguanosine formation by coarse and fine particulate matter.
Occupational and environmental medicine 2003;60(5):315-21.
2002: Roel P F Schins; Rodger Duffin; Doris Höhr; Ad M Knaapen; Tingming Shi; Christel Weishaupt; Vicki Stone; Ken Donaldson; Paul J A Borm
Surface modification of quartz inhibits toxicity, particle uptake, and oxidative DNA damage in human lung epithelial cells.
Chemical research in toxicology 2002;15(9):1166-73.
2002: Ad M Knaapen; Catrin Albrecht; Andrea Becker; Doris Höhr; Astrid Winzer; Guido R M M Haenen; Paul J A Borm; Roel P F Schins
DNA damage in lung epithelial cells isolated from rats exposed to quartz: role of surface reactivity and neutrophilic inflammation.
Carcinogenesis 2002;23(7):1111-20.
2002: Roel P F Schins; Ad M Knaapen; gonca cakmak demircigil; Tingming Shi; Christel Weishaupt; Paul J A Borm
Oxidant-induced DNA damage by quartz in alveolar epithelial cells.
Mutation research 2002;517(1-2):77-86.
2002: Ad M Knaapen; Tingming Shi; Paul J A Borm; Roel P F Schins
Soluble metals as well as the insoluble particle fraction are involved in cellular DNA damage induced by particulate matter.
Molecular and cellular biochemistry 2002;234-235(1-2):317-26.
2002: Ad M Knaapen; Roel P F Schins; Dünya Polat; Andrea Becker; Paul J A Borm
Mechanisms of neutrophil-induced DNA damage in respiratory tract epithelial cells.
Molecular and cellular biochemistry 2002;234-235(1-2):143-51.
2002: Doris Höhr; Yvonne Steinfartz; Roel P F Schins; Ad M Knaapen; Gianmario Martra; Bice Fubini; Paul J A Borm
The surface area rather than the surface coating determines the acute inflammatory response after instillation of fine and ultrafine TiO2 in the rat.
International journal of hygiene and environmental health 2002;205(3):239-44.
2001: Ad M Knaapen; G J den Hartog; A Bast; Paul J A Borm
Ambient particulate matter induces relaxation of rat aortic rings in vitro.
Human & experimental toxicology 2001;20(5):259-65.
1999: Jan M S van Maanen; Paul J A Borm; Ad M Knaapen; Marcel H M van Herwijnen; P A E L Schilderman; K R Smith; A E Aust; Maura Tomatis; Bice Fubini
In vitro effects of coal fly ashes: hydroxyl radical generation, iron release, and DNA damage and toxicity in rat lung epithelial cells.
Inhalation toxicology 1999;11(12):1123-41.
1999: Ad M Knaapen; Frank Seiler; P A E L Schilderman; P Nehls; Joachim Bruch; Roel P F Schins; Paul J A Borm
Neutrophils cause oxidative DNA damage in alveolar epithelial cells.
Free radical biology & medicine 1999;27(1-2):234-40.
1997: Paul J A Borm; Ad M Knaapen; Roel P F Schins; Roger Godschalk; F J Schooten
Neutrophils amplify the formation of DNA adducts by benzo[a]pyrene in lung target cells.
Environmental health perspectives 1997;105 Suppl 5():1089-93.