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Hans-Günther Knaus

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Chemicals & Drugs

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Levent Kaya; Hans-Günther Knaus; Herbert Lindner; Barbara Meissner; Martin Muik; Maria Christine Riedl; Christoph Romanin; Bettina Sarg; Christoph Schwarzer; Rüdiger Schweigreiter; Francesco Ferraguti; Christine E Bandtlow
Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.
Lie Chen; Hans-Günther Knaus; Heather McClafferty; Peter Ruth; Franziska Steeb; Lijun Tian; Danlei Bi; Michael Shipston
Palmitoylation of the β4-Subunit Regulates Surface Expression of Large Conductance Calcium-activated Potassium Channel Splice Variants.
Lijun Tian; Hans-Günther Knaus; Heather McClafferty; Peter Ruth; Michael Shipston
Distinct acyl protein transferases and thioesterases control surface expression of calcium-activated potassium channels.

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2013: Levent Kaya; Hans-Günther Knaus; Herbert Lindner; Barbara Meissner; Martin Muik; Maria Christine Riedl; Christoph Romanin; Bettina Sarg; Christoph Schwarzer; Rüdiger Schweigreiter; Francesco Ferraguti; Christine E Bandtlow
Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.
Biochimica et biophysica acta 2013;1833(6):1421-33.
2013: Lie Chen; Hans-Günther Knaus; Heather McClafferty; Peter Ruth; Franziska Steeb; Lijun Tian; Danlei Bi; Michael Shipston
Palmitoylation of the β4-Subunit Regulates Surface Expression of Large Conductance Calcium-activated Potassium Channel Splice Variants.
The Journal of biological chemistry 2013;288(18):13136-44.
2012: Lijun Tian; Hans-Günther Knaus; Heather McClafferty; Peter Ruth; Michael Shipston
Distinct acyl protein transferases and thioesterases control surface expression of calcium-activated potassium channels.
The Journal of biological chemistry 2012;287(18):14718-25.
2010: Owen Jeffries; Nina Geiger; Iain C M Rowe; Lijun Tian; Heather McClafferty; Lie Chen; Danlei Bi; Hans-Günther Knaus; Peter Ruth; Michael Shipston
Palmitoylation of the S0-S1 linker regulates cell surface expression of voltage- and calcium-activated potassium (BK) channels.
The Journal of biological chemistry 2010;285(43):33307-14.
2010: Catrin Swantje Müller; Alexander Haupt; Wolfgang Bildl; Jens Schindler; Hans-Günther Knaus; Marcel Meissner; Burkhard Rammner; Jörg Striessnig; Veit Flockerzi; Bernd Fakler; Uwe Schulte
Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(34):14950-7.
2010: Lie Chen; Owen Jeffries; Iain C M Rowe; Zhi Liang; Hans-Günther Knaus; Peter Ruth; Michael Shipston
Membrane trafficking of large conductance calcium-activated potassium channels is regulated by alternative splicing of a transplantable, acidic trafficking motif in the RCK1-RCK2 linker.
The Journal of biological chemistry 2010;285(30):23265-75.
2008: Lijun Tian; Owen Jeffries; Heather McClafferty; Adam Molyvdas; Iain C M Rowe; Fozia Saleem; Lie Chen; Jennifer Greaves; Luke H Chamberlain; Hans-Günther Knaus; Peter Ruth; Michael Shipston
Palmitoylation gates phosphorylation-dependent regulation of BK potassium channels.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(52):21006-11.
2008: Michael Willis; Manuela Prokesch; Birgit Hutter-Paier; Manfred Windisch; Mats Stridsberg; Sushil K Mahata; Rudolf Kirchmair; Georg Wietzorrek; Hans-Günther Knaus; Kurt A Jellinger; Christian Humpel; Josef Marksteiner
Chromogranin B and Secretogranin II in transgenic mice overexpressing human APP751 with the London (V717I) and Swedish (K670M/N671L) mutations and in Alzheimer patients.
Journal of Alzheimer's disease : JAD 2008;13(2):123-35.
2007: Paula J Brunton; Matthias Sausbier; Georg Wietzorrek; Ulrike Sausbier; Hans-Günther Knaus; John A Russell; Peter Ruth; Michael Shipston
Hypothalamic-pituitary-adrenal axis hyporesponsiveness to restraint stress in mice deficient for large-conductance calcium- and voltage-activated potassium (BK) channels.
Endocrinology 2007;148(11):5496-506.
2007: Michael Willis; Birgit Hutter-Paier; Georg Wietzorrek; Manfred Windisch; Christian Humpel; Hans-Günther Knaus; Josef Marksteiner
Localization and expression of substance P in transgenic mice overexpressing human APP751 with the London (V717I) and Swedish (K670M/N671L) mutations.
Brain research 2007;1143():199-207.
2006: Lijun Tian; Lie Chen; Heather McClafferty; Claudia A Sailer; Peter Ruth; Hans-Günther Knaus; Michael Shipston
A noncanonical SH3 domain binding motif links BK channels to the actin cytoskeleton via the SH3 adapter cortactin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(14):2588-90.
2006: Christine Beeton; Heike Wulff; Nathan E Standifer; Philippe Azam; Katherine M Mullen; Michael Pennington; Aaron Kolski-Andreaco; Eric Wei; Alexandra Grino; Debra R Counts; Ping H Wang; Christine J LeeHealey; Brian S Andrews; Ananthakrishnan Sankaranarayanan; Daniel Homerick; Werner W Roeck; Jamshid Tehranzadeh; Kimber L Stanhope; Pavel Zimin; Peter J Havel; Stephen M Griffey; Hans-Günther Knaus; Gerald Nepom; George A Gutman; Peter A Calabresi; K George Chandy
Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(46):17414-9.
2006: Henrike Berkefeld; Claudia A Sailer; Wolfgang Bildl; Volker Rohde; Jörg Oliver Thumfart; Silke Eble; Norbert Klugbauer; Ellen Reisinger; Josef Bischofberger; Dominik Oliver; Hans-Günther Knaus; Uwe Schulte; Bernd Fakler
BKCa-Cav channel complexes mediate rapid and localized Ca2+-activated K+ signaling.
Science (New York, N.Y.) 2006;314(5799):615-20.
2006: Claudia A Sailer; Walter A Kaufmann; Michaela Kogler; Lie Chen; Ulrike Sausbier; Ole Petter Ottersen; Peter Ruth; Michael Shipston; Hans-Günther Knaus
Immunolocalization of BK channels in hippocampal pyramidal neurons.
The European journal of neuroscience 2006;24(2):442-54.
2006: Ulrike Sausbier; Matthias Sausbier; Claudia A Sailer; Claudia Arntz; Hans-Günther Knaus; Winfried Neuhuber; Peter Ruth
Ca2+ -activated K+ channels of the BK-type in the mouse brain.
Histochemistry and cell biology 2006;125(6):725-41.
2006: Uwe Schulte; Jörg Oliver Thumfart; Nikolaj Klöcker; Claudia A Sailer; Wolfgang Bildl; Martin L Biniossek; Doris Dehn; Thomas Deller; Silke Eble; Karen Abbass; Tanja Wangler; Hans-Günther Knaus; Bernd Fakler
The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.
Neuron 2006;49(5):697-706.
2006: Chou J Liu; Birgit T Priest; Randal M Bugianesi; Paula M Dulski; John P Felix; Ivy E Dick; Richard Brochu; Hans-Günther Knaus; Richard E Middleton; Gregory J Kaczorowski; Robert S Slaughter; Maria L Garcia; Martin G Köhler
A high-capacity membrane potential FRET-based assay for NaV1.8 channels.
Assay and drug development technologies 2006;4(1):37-48.
2006: Stephen H-F MacDonald; Peter Ruth; Hans-Günther Knaus; Michael Shipston
Increased large conductance calcium-activated potassium (BK) channel expression accompanied by STREX variant downregulation in the developing mouse CNS.
BMC developmental biology 2006;6():37.
2005: Lie Chen; Lijun Tian; Stephen H-F MacDonald; Heather McClafferty; Martin S L Hammond; Jean-Marc Huibant; Peter Ruth; Hans-Günther Knaus; Michael Shipston
Functionally diverse complement of large conductance calcium- and voltage-activated potassium channel (BK) alpha-subunits generated from a single site of splicing.
The Journal of biological chemistry 2005;280(39):33599-609.
2005: Horea Rus; CARLOS PARDO-VILLAMIZAR; Lina Hu; Erika Darrah; Cornelia Cudrici; Teodora Niculescu; Florin Niculescu; Katherine M Mullen; Rameeza Allie; Liping Guo; Heike Wulff; Christine Beeton; Susan I V Judge; Douglas A Kerr; Hans-Günther Knaus; K George Chandy; Peter A Calabresi
The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(31):11094-9.
2005: william Schmalhofer; Manuel Sanchez; Ge Dai; Ashvin Dewan; Lorena Secades; Markus Hanner; Hans-Günther Knaus; Owen B McManus; Martin Kohler; Gregory J Kaczorowski; Maria L Garcia
Role of the C-terminus of the high-conductance calcium-activated potassium channel in channel structure and function.
Biochemistry 2005;44(30):10135-44.
2005: Matthias Sausbier; Claudia Arntz; Iancu Bucurenciu; Hong Zhao; Xiao-Bo Zhou; Ulrike Sausbier; Susanne Feil; Simone Kamm; Kirill Essin; Claudia A Sailer; Usamah Abdullah; Peter Krippeit-Drews; Robert Feil; Franz Hofmann; Hans-Günther Knaus; Chris Kenyon; Michael Shipston; Johan F Storm; Winfried Neuhuber; Michael Korth; Rudolf Schubert; Maik Gollasch; Peter Ruth
Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice.
Circulation 2005;112(1):60-8.
2005: Timothy Strassmaier; Chris T Bond; Claudia A Sailer; Hans-Günther Knaus; James Maylie; John P Adelman
A novel isoform of SK2 assembles with other SK subunits in mouse brain.
The Journal of biological chemistry 2005;280(22):21231-6.
2004: Lijun Tian; Lorraine S Coghill; Heather McClafferty; Stephen H-F MacDonald; ferenc andrás antoni; Peter Ruth; Hans-Günther Knaus; Michael Shipston
Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11897-902.
2004: Heike Wulff; Hans-Günther Knaus; Michael Pennington; K George Chandy
K+ channel expression during B cell differentiation: implications for immunomodulation and autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):776-86.
2004: Claudia A Sailer; Walter A Kaufmann; Josef Marksteiner; Hans-Günther Knaus
Comparative immunohistochemical distribution of three small-conductance Ca2+-activated potassium channel subunits, SK1, SK2, and SK3 in mouse brain.
Molecular and cellular neurosciences 2004;26(3):458-69.
2004: Matthias Sausbier; Hua Hu; Claudia Arntz; Susanne Feil; Simone Kamm; H Adelsberger; Ulrike Sausbier; Claudia A Sailer; Robert Feil; Franz Hofmann; Michael Korth; Michael Shipston; Hans-Günther Knaus; D P Wolfer; Christine M Pedroarena; Johan F Storm; Peter Ruth
Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9474-8.
2004: Vikram Shakkottai; Chin-hua Chou; Salvatore Oddo; Claudia A Sailer; Hans-Günther Knaus; George A Gutman; Michael E Barish; Frank M LaFerla; K George Chandy
Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia.
The Journal of clinical investigation 2004;113(4):582-90.
2003: Gerald Obermair; Walter A Kaufmann; Hans-Günther Knaus; Bernhard E Flucher
The small conductance Ca2+-activated K+ channel SK3 is localized in nerve terminals of excitatory synapses of cultured mouse hippocampal neurons.
The European journal of neuroscience 2003;17(4):721-31.
2002: Claudia A Sailer; Hua Hu; Walter A Kaufmann; Maria Trieb; Christoph Schwarzer; Johan F Storm; Hans-Günther Knaus
Regional differences in distribution and functional expression of small-conductance Ca2+-activated K+ channels in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(22):9698-707.
2002: Bernt Pragl; alexandra koschak; Maria Trieb; Gerald Obermair; Walter A Kaufmann; Uli Gerster; Eric Blanc; Christoph Hahn; Heino Prinz; Gerhard Schütz; Hervé Darbon; Hermann J Gruber; Hans-Günther Knaus
Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The first high affinity fluorescence probes for voltage-gated K+ channels.
Bioconjugate chemistry 2002;13(3):416-25.
2002: Günter Freudenthaler; Markus Axmann; Hansgeorg Schindler; Bernt Pragl; Hans-Günther Knaus; Gerhard J Schütz
Ultrasensitive pharmacological characterisation of the voltage-gated potassium channel K(V)1.3 studied by single-molecule fluorescence microscopy.
Histochemistry and cell biology 2002;117(3):197-202.
2001: Hua Hu; LR Shao; S Chavoshy; Ning Gu; Maria Trieb; R Behrens; Petter Laake; Olaf Pongs; Hans-Günther Knaus; Ole Petter Ottersen; Johan F Storm
Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(24):9585-97.
2001: Nikolaj Klöcker; Dominik Oliver; J Peter Ruppersberg; Hans-Günther Knaus; Bernd Fakler
Developmental expression of the small-conductance Ca(2+)-activated potassium channel SK2 in the rat retina.
Molecular and cellular neurosciences 2001;17(3):514-20.
2000: Chris T Bond; Rolf Sprengel; John M Bissonnette; Walter A Kaufmann; David Pribnow; Torben R Neelands; Thorsten Storck; M Baetscher; J Jerecic; James Maylie; Hans-Günther Knaus; Peter H Seeburg; John P Adelman
Respiration and parturition affected by conditional overexpression of the Ca2+-activated K+ channel subunit, SK3.
Science (New York, N.Y.) 2000;289(5486):1942-6.
2000: Hermann J Gruber; Christoph D Hahn; Gerald Kada; Christian K Riener; G S Harms; W Ahrer; T G Dax; Hans-Günther Knaus
Anomalous fluorescence enhancement of Cy3 and cy3.5 versus anomalous fluorescence loss of Cy5 and Cy7 upon covalent linking to IgG and noncovalent binding to avidin.
Bioconjugate chemistry 2000;11(5):696-704.
2000: Christian Legros; V Pollmann; Hans-Günther Knaus; A M Farrell; Hervé Darbon; Pierre E Bougis; Marie-France Martin-Eauclaire; Olaf Pongs
Generating a high affinity scorpion toxin receptor in KcsA-Kv1.3 chimeric potassium channels.
The Journal of biological chemistry 2000;275(22):16918-24.
2000: Hermann J Gruber; Gerald Kada; Bernt Pragl; Christian K Riener; Christoph D Hahn; G S Harms; W Ahrer; T G Dax; K Hohenthanner; Hans-Günther Knaus
Preparation of thiol-reactive Cy5 derivatives from commercial Cy5 succinimidyl ester.
Bioconjugate chemistry 2000;11(2):161-6.
1999: siegmund wanner; Hartmut Glossmann; Hans-Günther Knaus; R Baker; William H Parsons; Kathleen M Rupprecht; Richard Brochu; charles cohen; william Schmalhofer; McHardy Smith; Vivien A Warren; Maria L Garcia; Gregory J Kaczorowski
WIN 17317-3, a new high-affinity probe for voltage-gated sodium channels.
Biochemistry 1999;38(34):11137-46.
1999: siegmund wanner; Robert O Koch; alexandra koschak; Maria Trieb; Maria L Garcia; Gregory J Kaczorowski; Hans-Günther Knaus
High-conductance calcium-activated potassium channels in rat brain: pharmacology, distribution, and subunit composition.
Biochemistry 1999;38(17):5392-400.
1999: Maria L Garcia; Markus Hanner; Hans-Günther Knaus; Robert S Slaughter; Gregory J Kaczorowski
Scorpion toxins as tools for studying potassium channels.
Methods in enzymology 1999;294():624-39.
1999: Maria L Garcia; Kathleen M Giangiacomo; Markus Hanner; Hans-Günther Knaus; Owen B McManus; william Schmalhofer; Gregory J Kaczorowski
Purification and functional reconstitution of high-conductance calcium-activated potassium channel from smooth muscle.
Methods in enzymology 1999;294():274-87.
1998: Markus Hanner; Rosane Vianna-Jorge; A Kamassah; william Schmalhofer; Hans-Günther Knaus; Gregory J Kaczorowski; Maria L Garcia
The beta subunit of the high conductance calcium-activated potassium channel. Identification of residues involved in charybdotoxin binding.
The Journal of biological chemistry 1998;273(26):16289-96.
1998: Lijun Tian; Hans-Günther Knaus; Michael Shipston
Glucocorticoid regulation of calcium-activated potassium channels mediated by serine/threonine protein phosphatase.
The Journal of biological chemistry 1998;273(22):13531-6.
1998: Alois Saria; C V Seidl; Hanspeter S Fischer; Robert O Koch; Stefan Telser; siegmund wanner; Christian Humpel; Maria L Garcia; Hans-Günther Knaus
Margatoxin increases dopamine release in rat striatum via voltage-gated K+ channels.
European journal of pharmacology 1998;343(2-3):193-200.
1998: alexandra koschak; Randal M Bugianesi; J Mitterdorfer; Gregory J Kaczorowski; Maria L Garcia; Hans-Günther Knaus
Subunit composition of brain voltage-gated potassium channels determined by hongotoxin-1, a novel peptide derived from Centruroides limbatus venom.
The Journal of biological chemistry 1998;273(5):2639-44.
1997: Robert O Koch; siegmund wanner; alexandra koschak; Markus Hanner; Christoph Schwarzer; Gregory J Kaczorowski; Robert S Slaughter; Maria L Garcia; Hans-Günther Knaus
Complex subunit assembly of neuronal voltage-gated K+ channels. Basis for high-affinity toxin interactions and pharmacology.
The Journal of biological chemistry 1997;272(44):27577-81.
1997: Markus Hanner; william Schmalhofer; Petraki Munujos; Hans-Günther Knaus; Gregory J Kaczorowski; Maria L Garcia
The beta subunit of the high-conductance calcium-activated potassium channel contributes to the high-affinity receptor for charybdotoxin.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):2853-8.
1997: L M Helms; John P Felix; Randal M Bugianesi; Maria L Garcia; S Stevens; Reid Leonard; Hans-Günther Knaus; R Koch; siegmund wanner; Gregory J Kaczorowski; Robert S Slaughter
Margatoxin binds to a homomultimer of K(V)1.3 channels in Jurkat cells. Comparison with K(V)1.3 expressed in CHO cells.
Biochemistry 1997;36(12):3737-44.
1997: alexandra koschak; Robert O Koch; J Liu; Gregory J Kaczorowski; P H Reinhart; Maria L Garcia; Hans-Günther Knaus
[125I]Iberiotoxin-D19Y/Y36F, the first selective, high specific activity radioligand for high-conductance calcium-activated potassium channels.
Biochemistry 1997;36(7):1943-52.
1997: Maria L Garcia; Markus Hanner; Hans-Günther Knaus; R Koch; william Schmalhofer; Robert S Slaughter; Gregory J Kaczorowski
Pharmacology of potassium channels.
Advances in pharmacology (San Diego, Calif.) 1997;39():425-71.
1996: Markus Hanner; Fabian F Moebius; A Flandorfer; Hans-Günther Knaus; Jörg Striessnig; E Kempner; Hartmut Glossmann
Purification, molecular cloning, and expression of the mammalian sigma1-binding site.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):8072-7.
1996: Gregory J Kaczorowski; Hans-Günther Knaus; Reid Leonard; Owen B McManus; Maria L Garcia
High-conductance calcium-activated potassium channels; structure, pharmacology, and function.
Journal of bioenergetics and biomembranes 1996;28(3):255-67.
1996: Hans-Günther Knaus; Christoph Schwarzer; Robert O Koch; A Eberhart; Gregory J Kaczorowski; H Glossmann; F Wunder; O Pongs; Maria L Garcia; Günther Sperk
Distribution of high-conductance Ca(2+)-activated K+ channels in rat brain: targeting to axons and nerve terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(3):955-63.
1995: Kathleen M Giangiacomo; M Garcia-Calvo; Hans-Günther Knaus; T J Mullmann; Maria L Garcia; Owen B McManus
Functional reconstitution of the large-conductance, calcium-activated potassium channel purified from bovine aortic smooth muscle.
Biochemistry 1995;34(48):15849-62.
1995: Hans-Günther Knaus; Robert O Koch; A Eberhart; Gregory J Kaczorowski; Maria L Garcia; Robert S Slaughter
[125I]margatoxin, an extraordinarily high affinity ligand for voltage-gated potassium channels in mammalian brain.
Biochemistry 1995;34(41):13627-34.
1995: Hans-Günther Knaus; A Eberhart; Robert O Koch; Petraki Munujos; william Schmalhofer; JW Warmke; Gregory J Kaczorowski; Maria L Garcia
Characterization of tissue-expressed alpha subunits of the high conductance Ca(2+)-activated K+ channel.
The Journal of biological chemistry 1995;270(38):22434-9.
1995: Petraki Munujos; Hans-Günther Knaus; Gregory J Kaczorowski; Maria L Garcia
Cross-linking of charybdotoxin to high-conductance calcium-activated potassium channels: identification of the covalently modified toxin residue.
Biochemistry 1995;34(34):10771-6.
1995: Maria L Garcia; Hans-Günther Knaus; Petraki Munujos; Robert S Slaughter; Gregory J Kaczorowski
Charybdotoxin and its effects on potassium channels.
The American journal of physiology 1995;269(1 Pt 1):C1-10.
1994: Fabian F Moebius; Markus Hanner; Hans-Günther Knaus; F Weber; Jörg Striessnig; Hartmut Glossmann
Purification and amino-terminal sequencing of the high affinity phenylalkylamine Ca2+ antagonist binding protein from guinea pig liver endoplasmic reticulum.
The Journal of biological chemistry 1994;269(46):29314-20.
1994: Hans-Günther Knaus; A Eberhart; H Glossmann; Petraki Munujos; Gregory J Kaczorowski; Maria L Garcia
Pharmacology and structure of high conductance calcium-activated potassium channels.
Cellular signalling 1994;6(8):861-70.
1994: Hans-Günther Knaus; A Eberhart; Gregory J Kaczorowski; Maria L Garcia
Covalent attachment of charybdotoxin to the beta-subunit of the high conductance Ca(2+)-activated K+ channel. Identification of the site of incorporation and implications for channel topology.
The Journal of biological chemistry 1994;269(37):23336-41.
1994: Hans-Günther Knaus; K Folander; M Garcia-Calvo; Maria L Garcia; Gregory J Kaczorowski; McHardy Smith; R Swanson
Primary sequence and immunological characterization of beta-subunit of high conductance Ca(2+)-activated K+ channel from smooth muscle.
The Journal of biological chemistry 1994;269(25):17274-8.
1994: M Garcia-Calvo; Hans-Günther Knaus; Maria L Garcia; Gregory J Kaczorowski; E S Kempner
Functional unit size of the charybdotoxin receptor in smooth muscle.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4718-22.
1994: Hans-Günther Knaus; Owen B McManus; S H Lee; william Schmalhofer; M Garcia-Calvo; L M Helms; M Sanchez; Kathleen M Giangiacomo; J P Reuben; A B Smith
Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels.
Biochemistry 1994;33(19):5819-28.
1994: Hans-Günther Knaus; M Garcia-Calvo; Gregory J Kaczorowski; Maria L Garcia
Subunit composition of the high conductance calcium-activated potassium channel from smooth muscle, a representative of the mSlo and slowpoke family of potassium channels.
The Journal of biological chemistry 1994;269(6):3921-4.
1994: M Garcia-Calvo; Hans-Günther Knaus; Owen B McManus; Kathleen M Giangiacomo; Gregory J Kaczorowski; Maria L Garcia
Purification and reconstitution of the high-conductance, calcium-activated potassium channel from tracheal smooth muscle.
The Journal of biological chemistry 1994;269(1):676-82.
1993: M Lakitsch; Hans-Günther Knaus; Gerda Topar; Christoph Romanin; R Boer; D Flockerzi; Jörg Striessnig; Hansgeorg Schindler; H D Hoeltje; Hartmut Glossmann
Heterogeneity of L-type calcium channel alpha 1 subunits: stereoselective discrimination of different populations by the novel 1,4-dihydropyridine B 874-67.
Molecular pharmacology 1993;43(2):293-301.
1992: Hans-Günther Knaus; T Moshammer; K Friedrich; H C Kang; Richard P Haugland; H Glossman
In vivo labeling of L-type Ca2+ channels by fluorescent dihydropyridines: evidence for a functional, extracellular heparin-binding site.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(8):3586-90.
1992: Hans-Günther Knaus; T Moshammer; H C Kang; Richard P Haugland; Hartmut Glossmann
A unique fluorescent phenylalkylamine probe for L-type Ca2+ channels. Coupling of phenylalkylamine receptors to Ca2+ and dihydropyridine binding sites.
The Journal of biological chemistry 1992;267(4):2179-89.
1992: Hans-Günther Knaus; Jörg Striessnig; S Hering; S Marrer; E Schwenner; Hans-Dieter Höltje; Hartmut Glossmann
[35S]sadopine, a novel high affinity, high specific activity, L-type Ca2+ channel probe: characterization of two equipotent diastereomers with opposite allosteric properties.
Molecular pharmacology 1992;41(2):298-307.
1991: G A Knaus; Hans-Günther Knaus; Alois Saria
Complex allosteric interaction of heparin with neurokinin-1 receptors.
European journal of pharmacology 1991;207(3):267-70.
1991: R Staudinger; Hans-Günther Knaus; Hartmut Glossmann
Positive heterotropic allosteric regulators of dihydropyridine binding increase the Ca2+ affinity of the L-type Ca2+ channel. Stereoselective reversal by the novel Ca2+ antagonist BM 20.1140.
The Journal of biological chemistry 1991;266(17):10787-95.
1991: Manfred Grabner; K Friedrich; Hans-Günther Knaus; Jörg Striessnig; F Scheffauer; R Staudinger; Walter J Koch; A Schwartz; Hartmut Glossmann
Calcium channels from Cyprinus carpio skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(3):727-31.
1991: Gerhard Kieselbach; R Ragaut; Hans-Günther Knaus; P König; Alois Saria; Christian Wiedermann
Neurokinin-1 receptors in the human eye. Characterization and autoradiographic distribution.
Annals of the New York Academy of Sciences 1991;632():466-7.
1991: G A Knaus; Hans-Günther Knaus; Alois Saria
Allosteric interaction of heparin with NK-1 receptors in rat striatal membranes.
Annals of the New York Academy of Sciences 1991;632():422-5.
1990: Hans-Günther Knaus; F Scheffauer; Christoph Romanin; Hansgeorg Schindler; Hartmut Glossmann
Heparin binds with high affinity to voltage-dependent L-type Ca2+ channels. Evidence for an agonistic action.
The Journal of biological chemistry 1990;265(19):11156-66.
1990: Gerhard Kieselbach; R Ragaut; Hans-Günther Knaus; P König; Christian Wiedermann
Autoradiographic analysis of binding sites for 125I-Bolton-Hunter-substance P in the human eye.
Peptides 1990;11(4):655-9.
1990: Christian Humpel; G A Knaus; Bernhard Auer; Hans-Günther Knaus; C Haring; E Theodorsson; Alois Saria
Effects of haloperidol and clozapine on preprotachykinin-A messenger RNA, tachykinin tissue levels, release and neurokinin-1 receptors in the striato-nigral system.
Synapse (New York, N.Y.) 1990;6(1):1-9.
1989: A Grassegger; Jörg Striessnig; M Weiler; Hans-Günther Knaus; Hartmut Glossmann
[3H]HOE166 defines a novel calcium antagonist drug receptor--distinct from the 1,4 dihydropyridine binding domain.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(6 Pt 2):752-9.
1989: Hartmut Glossmann; Jörg Striessnig; Hans-Günther Knaus; J Müller; A Grassegger; Hans-Dieter Höltje; S Marrer; L Hymel; Hansgeorg Schindler
Structure of calcium channels.
Annals of the New York Academy of Sciences 1989;560():198-214.
1988: Jörg Striessnig; Hans-Günther Knaus; Hartmut Glossmann
Photoaffinity-labelling of the calcium-channel-associated 1,4-dihydropyridine and phenylalkylamine receptor in guinea-pig hippocampus. A 195 kDa polypeptide carries both drug receptors and has similarities to the alpha 1 subunit of the purified skeletal-muscle calcium channel.
The Biochemical journal 1988;253(1):39-47.
1988: Jörg Striessnig; E Meusburger; Manfred Grabner; Hans-Günther Knaus; Hartmut Glossmann; J Kaiser; B Schölkens; R Becker; W Linz; R Henning
Evidence for a distinct Ca2+ antagonist receptor for the novel benzothiazinone compound HOE 166.
Naunyn-Schmiedeberg's archives of pharmacology 1988;337(3):331-40.
1987: Hans-Günther Knaus; Jörg Striessnig; A Koza; Hartmut Glossmann
Neurotoxic aminoglycoside antibiotics are potent inhibitors of [125I]-Omega-Conotoxin GVIA binding to guinea-pig cerebral cortex membranes.
Naunyn-Schmiedeberg's archives of pharmacology 1987;336(5):583-6.
1987: Jörg Striessnig; Hans-Günther Knaus; Manfred Grabner; K Moosburger; W Seitz; H Lietz; Hartmut Glossmann
Photoaffinity labelling of the phenylalkylamine receptor of the skeletal muscle transverse-tubule calcium channel.
FEBS letters 1987;212(2):247-53.