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Katherine Knight

Research Profile

Living Beings

Genes & Molecular Sequences

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B Lymphocyte Heavy Chain Gene Rearrangement

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Publications

TOP 3
Gregory R Robbins; Katherine L Knight
Mechanism for pre-B cell loss in VH-mutant rabbits.
Ana Pinheiro; Wessel van der Loo; Paulo C Alves; Katherine L Knight; Dennis Lanning; Rose G Mage; Pedro J Esteves
Molecular bases of genetic diversity and evolution of the immunoglobulin heavy chain variable region (IGHV) gene locus in leporids.
Venkata A Yeramilli; Katherine L Knight
Somatically diversified and proliferating transitional B cells: implications for peripheral B cell homeostasis.

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All Publications

2011: Gregory R Robbins; Katherine L Knight
Mechanism for pre-B cell loss in VH-mutant rabbits.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(9):4714-20.
2011: Ana Pinheiro; Wessel van der Loo; Paulo C Alves; Katherine L Knight; Dennis Lanning; Rose G Mage; Pedro J Esteves
Molecular bases of genetic diversity and evolution of the immunoglobulin heavy chain variable region (IGHV) gene locus in leporids.
Immunogenetics 2011;63(7):397-408.
2011: Venkata A Yeramilli; Katherine L Knight
Somatically diversified and proliferating transitional B cells: implications for peripheral B cell homeostasis.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(11):6437-44.
2011: Basile T Siewe; Susan L Kalis; Phong T Le; Pamela L Witte; Sangdun Choi; Simon J Conway; Laurel Druschitz; Katherine L Knight
In vitro requirement for periostin in B lymphopoiesis.
Blood 2011;117(14):3770-9.
2010: Basile T Siewe; Susan L Kalis; Pedro J Esteves; Tong Zhou; Katherine L Knight
A novel functional rabbit IL-7 isoform.
Developmental and comparative immunology 2010;34(8):828-36.
2010: Kari M Severson; Michael Mallozzi; Adam Driks; Katherine L Knight
B cell development in GALT: role of bacterial superantigen-like molecules.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):6782-9.
2010: Venkata A Yeramilli; Katherine L Knight
Requirement for BAFF and APRIL during B cell development in GALT.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(10):5527-36.
2009: Kari M Severson; Michael Mallozzi; Joel Bozue; Susan L Welkos; Christopher K Cote; Katherine L Knight; Adam Driks
Roles of the Bacillus anthracis spore protein ExsK in exosporium maturation and germination.
Journal of bacteriology 2009;191(24):7587-96.
2007: Paul J Jasper; Ki-Jong Rhee; Susan L Kalis; Periannan Sethupathi; Pi-Chen Yam; Shi-Kang Zhai; Katherine L Knight
B lymphocyte deficiency in IgH-transgenic rabbits.
European journal of immunology 2007;37(8):2290-9.
2007: Susan L Kalis; Shi-Kang Zhai; Pi-Chen Yam; Pamela L Witte; Katherine L Knight
Suppression of B lymphopoiesis at a lymphoid progenitor stage in adult rabbits.
International immunology 2007;19(6):801-11.
2006: Rose G Mage; Dennis Lanning; Katherine L Knight
B cell and antibody repertoire development in rabbits: the requirement of gut-associated lymphoid tissues.
Developmental and comparative immunology 2006;30(1-2):137-53.
2005: pedro esteves; Dennis Lanning; Nuno Ferrand; Katherine L Knight; Shi-Kang Zhai; Wessel van der Loo
The evolution of the immunoglobulin heavy chain variable region (IgVH) in Leporids: an unusual case of transspecies polymorphism.
Immunogenetics 2005;57(11):874-82.
2005: Malathy Shanmugam; Periannan Sethupathi; Ki-Jong Rhee; Sherri Yong; Katherine L Knight
Bacterial-induced inflammation in germ-free rabbit appendix.
Inflammatory bowel diseases 2005;11(11):992-6.
2005: Dennis K Lanning; Katherine L Knight
Intestinal bacteria and development of the antibody repertoire.
Discovery medicine 2005;5(28):393-8.
2005: Veronica Victorovna Volgina; Pi-Chen Yam; Katherine L Knight
A negative regulatory element in the rabbit 3'IgH chromosomal region.
International immunology 2005;17(8):973-82.
2005: Dennis Lanning; Ki-Jong Rhee; Katherine L Knight
Intestinal bacteria and development of the B-lymphocyte repertoire.
Trends in immunology 2005;26(8):419-25.
2005: Kathy Cho; Shi-Kang Zhai; pedro esteves; Katherine L Knight
Characterization of the T-cell receptor gamma locus and analysis of the variable gene segment expression in rabbit.
Immunogenetics 2005;57(5):352-63.
2005: Ki-Jong Rhee; Paul J Jasper; Periannan Sethupathi; Malathy Shanmugam; Dennis Lanning; Katherine L Knight
Positive selection of the peripheral B cell repertoire in gut-associated lymphoid tissues.
The Journal of experimental medicine 2005;201(1):55-62.
2004: Ki-Jong Rhee; Periannan Sethupathi; Adam Driks; Dennis Lanning; Katherine L Knight
Role of commensal bacteria in development of gut-associated lymphoid tissues and preimmune antibody repertoire.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1118-24.
2004: pedro esteves; Dennis Lanning; Nuno Ferrand; Katherine L Knight; Shi-Kang Zhai; Wessel van der Loo
Allelic variation at the VHa locus in natural populations of rabbit (Oryctolagus cuniculus, L.).
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1044-53.
2003: Paul J Jasper; Shi-Kang Zhai; Susan L Kalis; Mae Kingzette; Katherine L Knight
B lymphocyte development in rabbit: progenitor B cells and waning of B lymphopoiesis.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6372-80.
2003: Dennis Lanning; Shi-Kang Zhai; Katherine L Knight
Analysis of the 3' Cmu region of the rabbit Ig heavy chain locus.
Gene 2003;309(2):135-44.
2002: Helga Spieker-Polet; Pi-Chen Yam; Katherine L Knight
Functional analysis of I alpha promoter regions of multiple IgA heavy chain genes.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3360-8.
2001: S M Hayes; Katherine L Knight
Group 1 CD1 genes in rabbit.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):403-10.
2000: Veronica Victorovna Volgina; Mae Kingzette; Shi-Kang Zhai; Katherine L Knight
A single 3' alpha hs1,2 enhancer in the rabbit IgH locus.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(11):6400-5.
2000: Dennis Lanning; Periannan Sethupathi; Ki-Jong Rhee; Shi-Kang Zhai; Katherine L Knight
Intestinal microflora and diversification of the rabbit antibody repertoire.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):2012-9.
2000: Dennis Lanning; X Zhu; Shi-Kang Zhai; Katherine L Knight
Development of the antibody repertoire in rabbit: gut-associated lymphoid tissue, microbes, and selection.
Immunological reviews 2000;175():214-28.
1999: X Zhu; A Boonthum; Shi-Kang Zhai; Katherine L Knight
B lymphocyte selection and age-related changes in VH gene usage in mutant Alicia rabbits.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3313-20.
1999: CR Winstead; Shi-Kang Zhai; Periannan Sethupathi; Katherine L Knight
Antigen-induced somatic diversification of rabbit IgH genes: gene conversion and point mutation.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6602-12.
1999: Helga Spieker-Polet; Pi-Chen Yam; Zarema Arbieva; Shi-Kang Zhai; Katherine L Knight
In vitro induction of the expression of multiple IgA isotype genes in rabbit B cells by TGF-beta and IL-2.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(9):5380-8.
1999: R A Barrington; M Fasullo; Katherine L Knight
A role for RAD51 in the generation of immunoglobulin gene diversity in rabbits.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):911-9.
1998: Mae Kingzette; Helga Spieker-Polet; Pi-Chen Yam; Shi-Kang Zhai; Katherine L Knight
Trans-chromosomal recombination within the Ig heavy chain switch region in B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(20):11840-5.
1998: Katherine L Knight; R A Barrington
Somatic diversification of IgH genes in rabbit.
Immunological reviews 1998;162():37-47.
1998: M Vajdy; Periannan Sethupathi; Katherine L Knight
Dependence of antibody somatic diversification on gut-associated lymphoid tissue in rabbits.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(6):2725-9.
1998: Dennis Lanning; Katherine L Knight
Antibody diversification in the rabbit: historical and contemporary perspectives.
Current topics in microbiology and immunology 1998;229():45-57.
1997: Katherine L Knight
American Association of Immunologists Presidential Address: doing it together: a perspective on the process of experimental science.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(10):4645-52.
1997: Dennis Lanning; Katherine L Knight
Somatic hypermutation: mutations 3' of rabbit VDJ H-chain genes.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(9):4403-7.
1997: C Tunyaplin; Katherine L Knight
IgH gene rearrangements on the unexpressed allele in rabbit B cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(10):4805-11.
1997: Katherine L Knight; CR Winstead
Generation of antibody diversity in rabbits.
Current opinion in immunology 1997;9(2):228-32.
1997: Katherine L Knight; CR Winstead
B lymphocyte development in the rabbit.
International reviews of immunology 1997;15(3-4):129-63.
1996: M A Crane; M Kingzette; Katherine L Knight
Evidence for limited B-lymphopoiesis in adult rabbits.
The Journal of experimental medicine 1996;183(5):2119-21.
1995: Katherine L Knight; M A Crane
Development of the antibody repertoire in rabbits.
Annals of the New York Academy of Sciences 1995;764():198-206.
1995: H Spieker-Polet; Periannan Sethupathi; Pi-Chen Yam; Katherine L Knight
Rabbit monoclonal antibodies: generating a fusion partner to produce rabbit-rabbit hybridomas.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9348-52.
1995: C Tunyaplin; Katherine L Knight
Fetal VDJ gene repertoire in rabbit: evidence for preferential rearrangement of VH1.
European journal of immunology 1995;25(9):2583-7.
1995: Katherine L Knight; M Kingzette; M A Crane; Shi-Kang Zhai
Transchromosomally derived Ig heavy chains.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(2):684-91.
1994: Periannan Sethupathi; H Spieker-Polet; H Polet; Pi-Chen Yam; C Tunyaplin; Katherine L Knight
Lymphoid and non-lymphoid tumors in E kappa-myc transgenic rabbits.
Leukemia 1994;8(12):2144-55.
1994: C Raman; H Spieker-Polet; Pi-Chen Yam; Katherine L Knight
Preferential VH gene usage in rabbit Ig-secreting heterohybridomas.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(8):3935-45.
1994: M L Friedman; C Tunyaplin; Shi-Kang Zhai; Katherine L Knight
Neonatal VH, D, and JH gene usage in rabbit B lineage cells.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):632-41.
1994: Katherine L Knight; M A Crane
Generating the antibody repertoire in rabbit.
Advances in immunology 1994;56():179-218.
1993: M A Crane; C Raman; Katherine L Knight
An expanded view of the ontogeny of the rabbit humoral immune system.
Research in immunology 1993;144(6-7):486-91; discussion 491-4.
1993: H Spieker-Polet; Pi-Chen Yam; Katherine L Knight
Differential expression of 13 IgA-heavy chain genes in rabbit lymphoid tissues.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(12):5457-65.
1992: C Raman; Katherine L Knight
CD5+ B cells predominate in peripheral tissues of rabbit.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(12):3858-64.
1992: C Raman; Katherine L Knight
Identification and cloning of rabbit CD5.
Annals of the New York Academy of Sciences 1992;651():78-81.
1992: Luisa A DiPietro; Periannan Sethupathi; M Kingzette; Shi-Kang Zhai; M Suter; Katherine L Knight
Limited repertoire of utilized VH gene segments in a VHa3-allotype-suppressed rabbit.
International immunology 1992;4(5):555-61.
1992: Katherine L Knight
Restricted VH gene usage and generation of antibody diversity in rabbit.
Annual review of immunology 1992;10():593-616.
1991: J A Short; Periannan Sethupathi; Shi-Kang Zhai; Katherine L Knight
VDJ genes in VHa2 allotype-suppressed rabbits. Limited germline VH gene usage and accumulation of somatic mutations in D regions.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(11):4014-8.
1991: Katherine L Knight; R S Becker; Luisa A DiPietro
Restricted utilization of germ-line VH genes in rabbits: implications for inheritance of VH allotypes and generation of antibody diversity.
Advances in experimental medicine and biology 1991;292():235-44.
1991: B A Newman; G O Young-Cooper; C B Alexander; R S Becker; Katherine L Knight; A S Kelus; D Meier; Rose G Mage
Molecular analysis of recombination sites within the immunoglobulin heavy chain locus of the rabbit.
Immunogenetics 1991;34(2):101-9.
1990: R S Becker; Katherine L Knight
Somatic diversification of immunoglobulin heavy chain VDJ genes: evidence for somatic gene conversion in rabbits.
Cell 1990;63(5):987-97.
1990: R D Schneiderman; T F Lint; Katherine L Knight
Activation of the alternative pathway of complement by twelve different rabbit-mouse chimeric transfectoma IgA isotypes.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(1):233-7.
1990: Luisa A DiPietro; J A Short; Shi-Kang Zhai; A S Kelus; D Meier; Katherine L Knight
Limited number of immunoglobulin VH regions expressed in the mutant rabbit "Alicia".
European journal of immunology 1990;20(6):1401-4.
1990: Katherine L Knight; R S Becker
Molecular basis of the allelic inheritance of rabbit immunoglobulin VH allotypes: implications for the generation of antibody diversity.
Cell 1990;60(6):963-70.
1990: M Suter; R S Becker; Katherine L Knight
Rearrangement of VHa1-encoding Ig gene segment to the a2 chromosome in an a1/a2 heterozygous rabbit. Evidence for trans recombination.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(5):1997-2000.
1990: Luisa A DiPietro; Katherine L Knight
Restricted utilization of germ-line VH genes and diversity of D regions in rabbit splenic Ig mRNA.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(5):1969-73.
1990: H Spieker-Polet; N Sittisombut; Pi-Chen Yam; Katherine L Knight
Rabbit major histocompatibility complex. IV. Expression of major histocompatibility complex class II genes.
Journal of immunogenetics 1990;17(1-2):123-32.
1990: R S Becker; M Suter; Katherine L Knight
Restricted utilization of VH and DH genes in leukemic rabbit B cells.
European journal of immunology 1990;20(2):397-402.
1989: R C Burnett; W C Hanly; Shi-Kang Zhai; Katherine L Knight
The IgA heavy-chain gene family in rabbit: cloning and sequence analysis of 13 C alpha genes.
The EMBO journal 1989;8(13):4041-7.
1989: Rose G Mage; B A Newman; N Harindranath; K E Bernstein; R S Becker; Katherine L Knight
Evolutionary conservation of splice sites in sterile C mu transcripts and of immunoglobulin heavy chain (IgH) enhancer region sequences.
Molecular immunology 1989;26(10):1007-10.
1989: R D Schneiderman; W C Hanly; Katherine L Knight
Expression of 12 rabbit IgA C alpha genes as chimeric rabbit-mouse IgA antibodies.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7561-5.
1989: R S Becker; Shi-Kang Zhai; S J Currier; Katherine L Knight
Ig VH, DH, and JH germ-line gene segments linked by overlapping cosmid clones of rabbit DNA.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(4):1351-5.
1989: N Sittisombut; R G Tissot; Katherine L Knight
Rabbit major histocompatibility complex. III. Multiple class II DR beta genes and restriction fragment length polymorphism of the class II alpha and beta genes.
Journal of immunogenetics 1989;16(1):63-75.
1988: Katherine L Knight; M Suter; R S Becker
Genetic engineering of bovine Ig. Construction and characterization of hapten-binding bovine/murine chimeric IgE, IgA, IgG1, IgG2, and IgG3 molecules.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(10):3654-9.
1988: Katherine L Knight; H Spieker-Polet; D S Kazdin; V T Oi
Transgenic rabbits with lymphocytic leukemia induced by the c-myc oncogene fused with the immunoglobulin heavy chain enhancer.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(9):3130-4.
1988: N Sittisombut; J Mordacq; Katherine L Knight
Rabbit MHC. II. Sequence analysis of the R-DP alpha- and beta-genes.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(9):3237-43.
1988: S J Currier; J L Gallarda; Katherine L Knight
Partial molecular genetic map of the rabbit VH chromosomal region.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(5):1651-9.
1987: Katherine L Knight; R S Becker
Isolation of genes encoding bovine IgM, IgG, IgA and IgE chains.
Veterinary immunology and immunopathology 1987;17(1-4):17-24.
1987: Katherine L Knight; R D Schneiderman; R C Burnett
Expression of rabbit IgA heavy chain genes in E. coli and in murine myeloma cells.
Veterinary immunology and immunopathology 1987;17(1-4):279-89.
1987: Katherine L Knight; A Johnson; J E Coligan; T J Kindt
Partial amino acid sequence analysis of rabbit MHC class II molecules isolated from two-dimensional polyacrylamide gels.
Molecular immunology 1987;24(5):449-54.
1987: R C Burnett; R D Schneiderman; Katherine L Knight
Rabbit IgA heavy chain genes: cloning and in vitro expression.
Advances in experimental medicine and biology 1987;216A():15-22.
1986: N Sittisombut; Katherine L Knight
Rabbit major histocompatibility complex. I. Isolation and characterization of three subregions of class II genes.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(5):1871-5.
1985: J L Gallarda; K S Gleason; Katherine L Knight
Organization of rabbit immunoglobulin genes. I. Structure and multiplicity of germ-line VH genes.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(6):4222-8.
1984: C L Martens; S J Currier; Katherine L Knight
Molecular genetic analysis of genes encoding the heavy chains of rabbit IgG.
Journal of immunology (Baltimore, Md. : 1950) 1984;133(2):1022-7.
1983: K L Muth; W C Hanly; Katherine L Knight
Serologic cross-reactions among rabbit secretory IgA molecules: evidence for multiple subclasses of secretory IgA-f molecules.
Molecular immunology 1983;20(9):989-99.
1983: Katherine L Knight; K L Muth; C L Martens; S J Currier; J L Gallarda; W C Hanly
Serologic and molecular genetic studies of rabbit Ig heavy chains: evidence for additional C alpha and C gamma genes.
Annals of the New York Academy of Sciences 1983;409():39-47.
1982: Rose G Mage; S Dray; A Gilman-Sachs; C Hamers-Casterman; R Hamers; W C Hanly; T J Kindt; Katherine L Knight; W J Mandy; Jan Naessens
Rabbit heavy chain haplotypes--allotypic determinants expressed by VH-CH recombinants.
Immunogenetics 1982;15(3):287-97.
1981: A Gilman-Sachs; S Dray; Katherine L Knight
Genetic control of the expression of allelic Ig genes at the VH a locus in a1/a2 heterozygous rabbits.
European journal of immunology 1981;11(12):1001-5.
1980: Katherine L Knight; A L Leary; R G Tissot
Identification of two Ia-like alloantigens on rabbit B lymphocytes.
Immunogenetics 1980;10(5):443-53.