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David Knipe
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22
Coen, Donald
10
Brockman, Mark
9
Taylor, Travis
8
Schaffer, Priscilla
7
Morrison, Lynda
6
Uprichard, Susan
6
Da Costa, XJ
6
Kramer, Martha
5
Carroll, Michael
4
Garber, David
4
Verschoor, Admar
4
Zhu, Jia
4
McNamee, Elizabeth
3
Zhou, Changhong
3
Melroe, Gregory
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All Publications
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2009: Hoshino Yo; Pesnicak Lesley; Dowdell Kennichi C; Burbelo Peter D; Knipe David M; Straus Stephen E; Cohen Jeffrey I
Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs.
The Journal of infectious diseases 2009;200(7):1088-95.
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2009: Cliffe Anna R; Garber David A; Knipe David M
Transcription of the herpes simplex virus latency-associated transcript promotes the formation of facultative heterochromatin on lytic promoters.
Journal of virology 2009;83(16):8182-90.
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2009: Liu Xueqiao; Broberg Eeva; Watanabe Daisuke; Dudek Timothy; Deluca Neal; Knipe David M
Genetic engineering of a modified herpes simplex virus 1 vaccine vector.
Vaccine 2009;27(21):2760-7.
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2009: Hamirally Sofia; Kamil Jeremy P; Ndassa-Colday Yasmine M; Lin Alison J; Jahng Wan Jin; Baek Moon-Chang; Noton Sarah; Silva Laurie A; Simpson-Holley Martha; Knipe David M; Golan David E; Marto Jarrod A; Coen Donald M
Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress.
PLoS pathogens 2009;5(1):e1000275.
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2008: Brockman Mark A; Knipe David M
Herpes simplex virus as a tool to define the role of complement in the immune response to peripheral infection.
Vaccine 2008;26 Suppl 8():I94-9.
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2008: Cliffe Anna R; Knipe David M
Herpes simplex virus ICP0 promotes both histone removal and acetylation on viral DNA during lytic infection.
Journal of virology 2008;82(24):12030-8.
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2008: Liu Xueqiao; Fitzgerald Katherine; Kurt-Jones Evelyn; Finberg Robert; Knipe David M
Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(32):11335-9.
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2008: Hoshino Yo; Pesnicak Lesley; Dowdell Kennichi C; Lacayo Juan; Dudek Timothy; Knipe David M; Straus Stephen E; Cohen Jeffrey I
Comparison of immunogenicity and protective efficacy of genital herpes vaccine candidates herpes simplex virus 2 dl5-29 and dl5-29-41L in mice and guinea pigs.
Vaccine 2008;26(32):4034-40.
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2008: Silva Lindsey; Cliffe Anna; Chang Lynne; Knipe David M
Role for A-type lamins in herpesviral DNA targeting and heterochromatin modulation.
PLoS pathogens 2008;4(5):e1000071.
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2008: Johnson Karen E; Song Byeongwoon; Knipe David M
Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling.
Virology 2008;374(2):487-94.
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2008: Fontaine-Rodriguez Errin C; Knipe David M
Herpes simplex virus ICP27 increases translation of a subset of viral late mRNAs.
Journal of virology 2008;82(7):3538-45.
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2008: Knipe David M; Cliffe Anna
Chromatin control of herpes simplex virus lytic and latent infection.
Nature reviews. Microbiology 2008;6(3):211-21.
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2008: Dudek Timothy; Mathews Lydia C; Knipe David M
Disruption of the U(L)41 gene in the herpes simplex virus 2 dl5-29 mutant increases its immunogenicity and protective capacity in a murine model of genital herpes.
Virology 2008;372(1):165-75.
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2007: van Lint Allison L; Torres-Lopez Ernesto; Knipe David M
Immunization with a replication-defective herpes simplex virus 2 mutant reduces herpes simplex virus 1 infection and prevents ocular disease.
Virology 2007;368(2):227-31.
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2007: Dodson Allen W; Taylor Travis J; Knipe David M; Coen Donald M
Inhibitors of the sodium potassium ATPase that impair herpes simplex virus replication identified via a chemical screening approach.
Virology 2007;366(2):340-8.
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2007: Melroe Gregory T; Silva Lindsey; Schaffer Priscilla A; Knipe David M
Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction.
Virology 2007;360(2):305-21.
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2007: Watanabe Daisuke; Brockman Mark A; Ndung'u Thumbi; Mathews Lydia; Lucas William T; Murphy Cynthia G; Felber Barbara K; Pavlakis George N; Deluca Neal A; Knipe David M
Properties of a herpes simplex virus multiple immediate-early gene-deleted recombinant as a vaccine vector.
Virology 2007;357(2):186-98.
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2007: Kaur Amitinder; Sanford Hannah B; Garry Deirdre; Lang Sabine; Klumpp Sherry A; Watanabe Daisuke; Bronson Roderick T; Lifson Jeffrey D; Rosati Margherita; Pavlakis George N; Felber Barbara K; Knipe David M; Desrosiers Ronald C
Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus.
Virology 2007;357(2):199-214.
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2006: Orlando Joseph S; Balliet John W; Kushnir Anna S; Astor Todd L; Kosz-Vnenchak Magdalena; Rice Stephen A; Knipe David M; Schaffer Priscilla A
ICP22 is required for wild-type composition and infectivity of herpes simplex virus type 1 virions.
Journal of virology 2006;80(19):9381-90.
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2006: Brockman Mark A; Verschoor Admar; Zhu Jia; Carroll Michael C; Knipe David M
Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells.
Journal of virology 2006;80(14):7111-7.
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2006: Palliser Deborah; Chowdhury Dipanjan; Wang Qing-Yin; Lee Sandra J; Bronson Roderick T; Knipe David M; Lieberman Judy
An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection.
Nature 2006;439(7072):89-94.
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2005: Pesola Jean M; Zhu Jia; Knipe David M; Coen Donald M
Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production.
Journal of virology 2005;79(23):14516-25.
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2005: Wang Qing-Yin; Zhou Changhong; Johnson Karen E; Colgrove Robert C; Coen Donald M; Knipe David M
Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):16055-9.
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2005: Simpson-Holley Martha; Colgrove Robert C; Nalepa Grzegorz; Harper J Wade; Knipe David M
Identification and functional evaluation of cellular and viral factors involved in the alteration of nuclear architecture during herpes simplex virus 1 infection.
Journal of virology 2005;79(20):12840-51.
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2005: LaVail Jennifer H; Tauscher Andrew N; Hicks James W; Harrabi Ons; Melroe Gregory T; Knipe David M
Genetic and molecular in vivo analysis of herpes simplex virus assembly in murine visual system neurons.
Journal of virology 2005;79(17):11142-50.
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2005: Olesky Melanie; McNamee Elizabeth E; Zhou Changhong; Taylor Travis J; Knipe David M
Evidence for a direct interaction between HSV-1 ICP27 and ICP8 proteins.
Virology 2005;331(1):94-105.
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2004: Fontaine-Rodriguez Errin C; Taylor Travis J; Olesky Melanie; Knipe David M
Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors.
Virology 2004;330(2):487-92.
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2004: Melroe Gregory T; DeLuca Neal A; Knipe David M
Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production.
Journal of virology 2004;78(16):8411-20.
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2004: Taylor Travis J; Knipe David M
Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8.
Journal of virology 2004;78(11):5856-66.
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2004: Simpson-Holley Martha; Baines Joel; Roller Richard; Knipe David M
Herpes simplex virus 1 U(L)31 and U(L)34 gene products promote the late maturation of viral replication compartments to the nuclear periphery.
Journal of virology 2004;78(11):5591-600.
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2004: Pearson Angela; Knipe David M; Coen Donald M
ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells.
Journal of virology 2004;78(1):23-32.
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2004: Cook W James; Kramer Martha F; Walker Russell M; Burwell Timothy J; Holman Holly A; Coen Donald M; Knipe David M
Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection.
Virology journal 2004;1():5.
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2003: Verschoor Admar; Brockman Mark A; Gadjeva Mihaela; Knipe David M; Carroll Michael C
Myeloid C3 determines induction of humoral responses to peripheral herpes simplex virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5363-71.
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2003: Kramer Martha F; Cook W James; Roth Frederick P; Zhu Jia; Holman Holly; Knipe David M; Coen Donald M
Latent herpes simplex virus infection of sensory neurons alters neuronal gene expression.
Journal of virology 2003;77(17):9533-41.
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2003: Uprichard Susan L; Knipe David M
Conformational changes in the herpes simplex virus ICP8 DNA-binding protein coincident with assembly in viral replication structures.
Journal of virology 2003;77(13):7467-76.
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2003: Taylor Travis J; McNamee Elizabeth E; Day Cheryl; Knipe David M
Herpes simplex virus replication compartments can form by coalescence of smaller compartments.
Virology 2003;309(2):232-47.
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2003: Taylor Travis J; Knipe David M
C-terminal region of herpes simplex virus ICP8 protein needed for intranuclear localization.
Virology 2003;309(2):219-31.
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2003: Kramer Martha; Riley Jennifer; Spoering Amy; Coen Donald; Knipe David
Effect of immunization on herpes simplex virus type 1 latent infection in the trigeminal ganglion.
Current eye research 2003;26(3-4):185-94.
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2002: Gadjeva Mihaela; Verschoor Admar; Brockman Mark A; Jezak Heather; Shen Li Ming; Knipe David M; Carroll Michael C
Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5489-95.
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2002: Zhou Changhong; Knipe David M
Association of herpes simplex virus type 1 ICP8 and ICP27 proteins with cellular RNA polymerase II holoenzyme.
Journal of virology 2002;76(12):5893-904.
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2002: Chen Shun-Hua; Lee Lily Yeh; Garber David A; Schaffer Priscilla A; Knipe David M; Coen Donald M
Neither LAT nor open reading frame P mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virus.
Journal of virology 2002;76(10):4764-72.
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2002: Brockman Mark A; Knipe David M
Herpes simplex virus vectors elicit durable immune responses in the presence of preexisting host immunity.
Journal of virology 2002;76(8):3678-87.
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2002: Taylor Travis J; Brockman Mark A; McNamee Elizabeth E; Knipe David M
Herpes simplex virus.
Frontiers in bioscience : a journal and virtual library 2002;7():d752-64.
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2001: Song B; Yeh K C; Liu J; Knipe D M
Herpes simplex virus gene products required for viral inhibition of expression of G1-phase functions.
Virology 2001;290(2):320-8.
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2001: Da Costa X J; Morrison L A; Knipe D M
Comparison of different forms of herpes simplex replication-defective mutant viruses as vaccines in a mouse model of HSV-2 genital infection.
Virology 2001;288(2):256-63.
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2001: Verschoor A; Brockman M A; Knipe D M; Carroll M C
Cutting edge: myeloid complement C3 enhances the humoral response to peripheral viral infection.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(5):2446-51.
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2001: Jean S; LeVan K M; Song B; Levine M; Knipe D M
Herpes simplex virus 1 ICP27 is required for transcription of two viral late (gamma 2) genes in infected cells.
Virology 2001;283(2):273-84.
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2000: Chen S H; Garber D A; Schaffer P A; Knipe D M; Coen D M
Persistent elevated expression of cytokine transcripts in ganglia latently infected with herpes simplex virus in the absence of ganglionic replication or reactivation.
Virology 2000;278(1):207-16.
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2000: Jones C A; Taylor T J; Knipe D M
Biological properties of herpes simplex virus 2 replication-defective mutant strains in a murine nasal infection model.
Virology 2000;278(1):137-50.
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2000: McNamee E E; Taylor T J; Knipe D M
A dominant-negative herpesvirus protein inhibits intranuclear targeting of viral proteins: effects on DNA replication and late gene expression.
Journal of virology 2000;74(21):10122-31.
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2000: Da Costa X; Kramer M F; Zhu J; Brockman M A; Knipe D M
Construction, phenotypic analysis, and immunogenicity of a UL5/UL29 double deletion mutant of herpes simplex virus 2.
Journal of virology 2000;74(17):7963-71.
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2000: Murphy C G; Lucas W T; Means R E; Czajak S; Hale C L; Lifson J D; Kaur A; Johnson R P; Knipe D M; Desrosiers R C
Vaccine protection against simian immunodeficiency virus by recombinant strains of herpes simplex virus.
Journal of virology 2000;74(17):7745-54.
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2000: Song B; Liu J J; Yeh K C; Knipe D M
Herpes simplex virus infection blocks events in the G1 phase of the cell cycle.
Virology 2000;267(2):326-34.
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1999: Da Costa X J; Brockman M A; Alicot E; Ma M; Fischer M B; Zhou X; Knipe D M; Carroll M C
Humoral response to herpes simplex virus is complement-dependent.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12708-12.
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1999: Da Costa X J; Jones C A; Knipe D M
Immunization against genital herpes with a vaccine virus that has defects in productive and latent infection.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6994-8.
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1998: de Bruyn Kops A; Uprichard S L; Chen M; Knipe D M
Comparison of the intranuclear distributions of herpes simplex virus proteins involved in various viral functions.
Virology 1998;252(1):162-78.
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1998: Hann L E; Cook W J; Uprichard S L; Knipe D M; Coen D M
The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation.
Journal of virology 1998;72(10):7709-14.
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1998: Morrison L A; Da Costa X J; Knipe D M
Influence of mucosal and parenteral immunization with a replication-defective mutant of HSV-2 on immune responses and protection from genital challenge.
Virology 1998;243(1):178-87.
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1998: Kramer M F; Chen S H; Knipe D M; Coen D M
Accumulation of viral transcripts and DNA during establishment of latency by herpes simplex virus.
Journal of virology 1998;72(2):1177-85.
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1997: Morrison L A; Knipe D M
Contributions of antibody and T cell subsets to protection elicited by immunization with a replication-defective mutant of herpes simplex virus type 1.
Virology 1997;239(2):315-26.
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1997: Garber D A; Schaffer P A; Knipe D M
A LAT-associated function reduces productive-cycle gene expression during acute infection of murine sensory neurons with herpes simplex virus type 1.
Journal of virology 1997;71(8):5885-93.
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1997: Da Costa X J; Bourne N; Stanberry L R; Knipe D M
Construction and characterization of a replication-defective herpes simplex virus 2 ICP8 mutant strain and its use in immunization studies in a guinea pig model of genital disease.
Virology 1997;232(1):1-12.
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1997: Uprichard S L; Knipe D M
Assembly of herpes simplex virus replication proteins at two distinct intranuclear sites.
Virology 1997;229(1):113-25.
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1996: Brubaker J O; Thompson C M; Morrison L A; Knipe D M; Siber G R; Finberg R W
Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1598-604.
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1996: Chen Y M; Knipe D M
A dominant mutant form of the herpes simplex virus ICP8 protein decreases viral late gene transcription.
Virology 1996;221(2):281-90.
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1996: Morrison L A; Knipe D M
Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1.
Virology 1996;220(2):402-13.
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1996: Kanangat S; Babu J S; Knipe D M; Rouse B T
HSV-1-mediated modulation of cytokine gene expression in a permissive cell line: selective upregulation of IL-6 gene expression.
Virology 1996;219(1):295-300.
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1996: Uprichard S L; Knipe D M
Herpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genes.
Journal of virology 1996;70(3):1969-80.
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1996: Liptak L M; Uprichard S L; Knipe D M
Functional order of assembly of herpes simplex virus DNA replication proteins into prereplicative site structures.
Journal of virology 1996;70(3):1759-67.
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1996: Xia K; DeLuca N A; Knipe D M
Analysis of phosphorylation sites of herpes simplex virus type 1 ICP4.
Journal of virology 1996;70(2):1061-71.
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1996: Xia K; Knipe D M; DeLuca N A
Role of protein kinase A and the serine-rich region of herpes simplex virus type 1 ICP4 in viral replication.
Journal of virology 1996;70(2):1050-60.
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1996: Babu J S; Thomas J; Kanangat S; Morrison L A; Knipe D M; Rouse B T
Viral replication is required for induction of ocular immunopathology by herpes simplex virus.
Journal of virology 1996;70(1):101-7.
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1994: de Bruyn Kops A; Knipe D M
Preexisting nuclear architecture defines the intranuclear location of herpesvirus DNA replication structures.
Journal of virology 1994;68(6):3512-26.
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1994: Morrison L A; Knipe D M
Immunization with replication-defective mutants of herpes simplex virus type 1: sites of immune intervention in pathogenesis of challenge virus infection.
Journal of virology 1994;68(2):689-96.
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1994: Nguyen L; Knipe D M; Finberg R W
Mechanism of virus-induced Ig subclass shifts.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):478-84.
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1994: Davar G; Kramer M F; Garber D; Roca A L; Andersen J K; Bebrin W; Coen D M; Kosz-Vnenchak M; Knipe D M; Breakefield X O
Comparative efficacy of expression of genes delivered to mouse sensory neurons with herpes virus vectors.
The Journal of comparative neurology 1994;339(1):3-11.
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1994: Davar G; Kramer M F; Garber D; Roca A L; Andersen J K; Bebrin W; Coen D M; Kosz-Vnenchak M; Knipe D M; Breakefield X O
Gene transfer to sensory neurons using herpes virus vectors.
Gene therapy 1994;1 Suppl 1():S24.
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1993: Jacobson J G; Ruffner K L; Kosz-Vnenchak M; Hwang C B; Wobbe K K; Knipe D M; Coen D M
Herpes simplex virus thymidine kinase and specific stages of latency in murine trigeminal ganglia.
Journal of virology 1993;67(11):6903-8.
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1993: Curtin K D; Knipe D M
Altered properties of the herpes simplex virus ICP8 DNA-binding protein in cells infected with ICP27 mutant viruses.
Virology 1993;196(1):1-14.
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1993: Kosz-Vnenchak M; Jacobson J; Coen D M; Knipe D M
Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons.
Journal of virology 1993;67(9):5383-93.
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1993: Gao M; Knipe D M
Intragenic complementation of herpes simplex virus ICP8 DNA-binding protein mutants.
Journal of virology 1993;67(2):876-85.
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1992: Nguyen L H; Knipe D M; Finberg R W
Replication-defective mutants of herpes simplex virus (HSV) induce cellular immunity and protect against lethal HSV infection.
Journal of virology 1992;66(12):7067-72.
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1992: Gao M; Knipe D M
Distal protein sequences can affect the function of a nuclear localization signal.
Molecular and cellular biology 1992;12(3):1330-9.
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1991: Gibbs J S; Weisshart K; Digard P; deBruynKops A; Knipe D M; Coen D M
Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site.
Molecular and cellular biology 1991;11(9):4786-95.
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1991: Gao M; Knipe D M
Potential role for herpes simplex virus ICP8 DNA replication protein in stimulation of late gene expression.
Journal of virology 1991;65(5):2666-75.
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1991: Bush M; Yager D R; Gao M; Weisshart K; Marcy A I; Coen D M; Knipe D M
Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein.
Journal of virology 1991;65(3):1082-9.
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1990: Kosz-Vnenchak M; Coen D M; Knipe D M
Restricted expression of herpes simplex virus lytic genes during establishment of latent infection by thymidine kinase-negative mutant viruses.
Journal of virology 1990;64(11):5396-402.
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1990: Rice S A; Knipe D M
Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.
Journal of virology 1990;64(4):1704-15.
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1989: Gao M; Knipe D M
Genetic evidence for multiple nuclear functions of the herpes simplex virus ICP8 DNA-binding protein.
Journal of virology 1989;63(12):5258-67.
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1989: Rice S A; Su L S; Knipe D M
Herpes simplex virus alpha protein ICP27 possesses separable positive and negative regulatory activities.
Journal of virology 1989;63(8):3399-407.
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1989: Leib D A; Bogard C L; Kosz-Vnenchak M; Hicks K A; Coen D M; Knipe D M; Schaffer P A
A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency.
Journal of virology 1989;63(7):2893-900.
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1989: Coen D M; Kosz-Vnenchak M; Jacobson J G; Leib D A; Bogard C L; Schaffer P A; Tyler K L; Knipe D M
Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4736-40.
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1989: Su L; Knipe D M
Herpes simplex virus alpha protein ICP27 can inhibit or augment viral gene transactivation.
Virology 1989;170(2):496-504.
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1989: Leib D A; Coen D M; Bogard C L; Hicks K A; Yager D R; Knipe D M; Tyler K L; Schaffer P A
Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.
Journal of virology 1989;63(2):759-68.
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1989: Knipe D M
The role of viral and cellular nuclear proteins in herpes simplex virus replication.
Advances in virus research 1989;37():85-123.
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1988: de Bruyn Kops A; Knipe D M
Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein.
Cell 1988;55(5):857-68.
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1988: Rice S A; Knipe D M
Gene-specific transactivation by herpes simplex virus type 1 alpha protein ICP27.
Journal of virology 1988;62(10):3814-23.
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1988: Gao M; Bouchey J; Curtin K; Knipe D M
Genetic identification of a portion of the herpes simplex virus ICP8 protein required for DNA-binding.
Virology 1988;163(2):319-29.
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