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David Knipe

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Physiology

Disorders

Herpes Simplex

Genes & Molecular Sequences

Genes, Viral

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Publications

TOP 3
Jayita Sen; Xueqiao Liu; Richard J Roller; David M Knipe
Herpes simplex virus US3 tegument protein inhibits Toll-like receptor 2 signaling at or before TRAF6 ubiquitination.
David M Knipe; Jae U. Jung; Paul M Lieberman; David Margolis; Alison A McBride; Kevin V Morris; Michael Nevels; Amelia Nieto; Melanie Ott; Robin J Parks; Thomas M Kristie
Snapshots: chromatin control of viral infection.
Anna R Cliffe; Donald M Coen; David M Knipe
Kinetics of facultative heterochromatin and polycomb group protein association with the herpes simplex viral genome during establishment of latent infection.

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All Publications

2013: Jayita Sen; Xueqiao Liu; Richard J Roller; David M Knipe
Herpes simplex virus US3 tegument protein inhibits Toll-like receptor 2 signaling at or before TRAF6 ubiquitination.
Virology 2013;439(2):65-73.
2013: David M Knipe; Jae U. Jung; Paul M Lieberman; David Margolis; Alison A McBride; Kevin V Morris; Michael Nevels; Amelia Nieto; Melanie Ott; Robin J Parks; Thomas M Kristie
Snapshots: chromatin control of viral infection.
Virology 2013;435(1):141-56.
2013: Anna R Cliffe; Donald M Coen; David M Knipe
Kinetics of facultative heterochromatin and polycomb group protein association with the herpes simplex viral genome during establishment of latent infection.
mBio 2013;4(1):.
2012: Megan H Orzalli; Neal A DeLuca; David M Knipe
Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(44):E3008-17.
2012: Kevin F Bryant; David H Dreyfus; Zhipeng Yan; David M Knipe
Identification of a divalent metal cation binding site in herpes simplex virus 1 (HSV-1) ICP8 required for HSV replication.
Journal of virology 2012;86(12):6825-34.
2012: Lindsey Silva; Steven J Triezenberg; Zhipeng Yan; Lynne Chang; Hyung Suk Oh; David M Knipe
Roles of the nuclear lamina in stable nuclear association and assembly of a herpesviral transactivator complex on viral immediate-early genes.
mBio 2012;3(1):.
2011: Martha F Kramer; Jean M Pesola; Sandrine Boissel; Igor Jurak; David M Knipe; Donald M Coen
Herpes simplex virus 1 microRNAs expressed abundantly during latent infection are not essential for latency in mouse trigeminal ganglia.
Virology 2011;417(2):239-47.
2011: Ping Rao; Yang Yang; Peter Cresswell; David M Knipe; Arpita Kulkarni; Xueqiao Liu; Hong Thanh Pham; Weiming Yuan
Herpes simplex virus 1 glycoprotein B and US3 collaborate to inhibit CD1d antigen presentation and NKT cell function.
Journal of virology 2011;85(16):8093-104.
2011: Lynne Chang; William J Godinez; Il-Han Kim; Marco Tektonidis; Primal De Lanerolle; Roland Eils; Karl Rohr; David M Knipe
Herpesviral replication compartments move and coalesce at nuclear speckles to enhance export of viral late mRNA.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(21):E136-44.
2011: Timothy E Dudek; ERNESTO TORRES-LOPEZ; Clyde S Crumpacker; David M Knipe
Evidence for differences in immunologic and pathogenesis properties of herpes simplex virus 2 strains from the United States and South Africa.
The Journal of infectious diseases 2011;203(10):1434-41.
2011: Kevin F Bryant; Robert C Colgrove; David M Knipe
Cellular SNF2H chromatin-remodeling factor promotes herpes simplex virus 1 immediate-early gene expression and replication.
mBio 2011;2(1):e00330-10.
2010: Igor Jurak; Martha F Kramer; Joseph C Mellor; Alison L van Lint; Frederick P Roth; David M Knipe; Donald M Coen
Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2.
Journal of virology 2010;84(9):4659-72.
2010: Natalia Reszka; Timothy Dudek; David M Knipe
Construction and properties of a herpes simplex virus 2 dl5-29 vaccine candidate strain encoding an HSV-1 virion host shutoff protein.
Vaccine 2010;28(15):2754-62.
2010: Natalia Reszka; Changhong Zhou; Byeongwoon Song; Joseph G Sodroski; David M Knipe
Simian TRIM5alpha proteins reduce replication of herpes simplex virus.
Virology 2010;398(2):243-50.
2010: Karen E Johnson; David M Knipe
Herpes simplex virus-1 infection causes the secretion of a type I interferon-antagonizing protein and inhibits signaling at or before Jak-1 activation.
Virology 2010;396(1):21-9.
2009: Yo Hoshino; Lesley Pesnicak; Kennichi C Dowdell; Peter D Burbelo; David M Knipe; Stephen E Straus; Jeffrey I Cohen
Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs.
The Journal of infectious diseases 2009;200(7):1088-95.
2009: Anna R Cliffe; David A Garber; David M Knipe
Transcription of the herpes simplex virus latency-associated transcript promotes the formation of facultative heterochromatin on lytic promoters.
Journal of virology 2009;83(16):8182-90.
2009: Xueqiao Liu; Eeva Broberg; Daisuke Watanabe; Timothy Dudek; Neal A DeLuca; David M Knipe
Genetic engineering of a modified herpes simplex virus 1 vaccine vector.
Vaccine 2009;27(21):2760-7.
2009: Sofia Hamirally; Jeremy P Kamil; Yasmine M Ndassa-Colday; Alison J Lin; Wan Jin Jahng; Moon-Chang Baek; Sarah Noton; Laurie A Silva; Martha Simpson-Holley; David M Knipe; David E Golan; Jarrod A Marto; Donald M Coen
Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress.
PLoS pathogens 2009;5(1):e1000275.
2008: Mark Alan Brockman; David M Knipe
Herpes simplex virus as a tool to define the role of complement in the immune response to peripheral infection.
Vaccine 2008;26 Suppl 8():I94-9.
2008: Anna R Cliffe; David M Knipe
Herpes simplex virus ICP0 promotes both histone removal and acetylation on viral DNA during lytic infection.
Journal of virology 2008;82(24):12030-8.
2008: Xueqiao Liu; Katherine Fitzgerald; Evelyn Kurt-Jones; Robert Finberg; David M Knipe
Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(32):11335-9.
2008: yo hoshino; Lesley Pesnicak; Kennichi C Dowdell; Juan Lacayo; Timothy Dudek; David M Knipe; Stephen E Straus; Jeffrey I Cohen
Comparison of immunogenicity and protective efficacy of genital herpes vaccine candidates herpes simplex virus 2 dl5-29 and dl5-29-41L in mice and guinea pigs.
Vaccine 2008;26(32):4034-40.
2008: Karen E Johnson; Byeongwoon Song; David M Knipe
Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling.
Virology 2008;374(2):487-94.
2008: Lindsey Silva; Anna Cliffe; Lynne Chang; David M Knipe
Role for A-type lamins in herpesviral DNA targeting and heterochromatin modulation.
PLoS pathogens 2008;4(5):e1000071.
2008: Errin C Fontaine-Rodriguez; David M Knipe
Herpes simplex virus ICP27 increases translation of a subset of viral late mRNAs.
Journal of virology 2008;82(7):3538-45.
2008: David M Knipe; Anna Cliffe
Chromatin control of herpes simplex virus lytic and latent infection.
Nature reviews. Microbiology 2008;6(3):211-21.
2008: Tim Dudek; Lydia C Mathews; David M Knipe
Disruption of the U(L)41 gene in the herpes simplex virus 2 dl5-29 mutant increases its immunogenicity and protective capacity in a murine model of genital herpes.
Virology 2008;372(1):165-75.
2007: Allison L van Lint; ERNESTO TORRES-LOPEZ; David M Knipe
Immunization with a replication-defective herpes simplex virus 2 mutant reduces herpes simplex virus 1 infection and prevents ocular disease.
Virology 2007;368(2):227-31.
2007: Allen W Dodson; Travis J Taylor; David M Knipe; Donald M Coen
Inhibitors of the sodium potassium ATPase that impair herpes simplex virus replication identified via a chemical screening approach.
Virology 2007;366(2):340-8.
2007: Gregory T Melroe; Lindsey Silva; Priscilla A Schaffer; David M Knipe
Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction.
Virology 2007;360(2):305-21.
2007: Daisuke Watanabe; Mark Alan Brockman; Thumbi Ndung'u; Lydia Mathews; William Lucas; Cynthia G Murphy; Barbara K Felber; George Pavlakis; Neal A Deluca; David M Knipe
Properties of a herpes simplex virus multiple immediate-early gene-deleted recombinant as a vaccine vector.
Virology 2007;357(2):186-98.
2007: Amitinder Kaur; Hannah B Sanford; Deirdre Garry; Sabine Lang; Sherry A Klumpp; Daisuke Watanabe; Roderick T Bronson; Jeffrey D Lifson; margherita rosati; George Pavlakis; Barbara K Felber; David M Knipe; Ronald C Desrosiers
Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus.
Virology 2007;357(2):199-214.
2006: Joseph S Orlando; John W Balliet; Anna S Kushnir; Todd L Astor; Magdalena Kosz-Vnenchak; Stephen A Rice; David M Knipe; Priscilla A Schaffer
ICP22 is required for wild-type composition and infectivity of herpes simplex virus type 1 virions.
Journal of virology 2006;80(19):9381-90.
2006: Mark Alan Brockman; Admar Verschoor; Jia Zhu; Michael C Carroll; David M Knipe
Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells.
Journal of virology 2006;80(14):7111-7.
2006: Deborah Palliser; Dipanjan Chowdhury; Qing-Yin Wang; Sandra Lee; Roderick T Bronson; David M Knipe; Judy Lieberman
An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection.
Nature 2006;439(7072):89-94.
2005: Jean M Pesola; Jia Zhu; David M Knipe; Donald M Coen
Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production.
Journal of virology 2005;79(23):14516-25.
2005: Qing-Yin Wang; Changhong Zhou; Karen E Johnson; Robert C Colgrove; Donald M Coen; David M Knipe
Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):16055-9.
2005: Martha Simpson-Holley; Robert C Colgrove; Grzegorz Nalepa; J Wade Harper; David M Knipe
Identification and functional evaluation of cellular and viral factors involved in the alteration of nuclear architecture during herpes simplex virus 1 infection.
Journal of virology 2005;79(20):12840-51.
2005: Jennifer H LaVail; Andrew N Tauscher; James W Hicks; Ons Harrabi; Gregory T Melroe; David M Knipe
Genetic and molecular in vivo analysis of herpes simplex virus assembly in murine visual system neurons.
Journal of virology 2005;79(17):11142-50.
2005: Melanie Olesky; Elizabeth E McNamee; Changhong Zhou; Travis J Taylor; David M Knipe
Evidence for a direct interaction between HSV-1 ICP27 and ICP8 proteins.
Virology 2005;331(1):94-105.
2004: Errin C Fontaine-Rodriguez; Travis J Taylor; Melanie Olesky; David M Knipe
Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors.
Virology 2004;330(2):487-92.
2004: Gregory T Melroe; Neal A DeLuca; David M Knipe
Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production.
Journal of virology 2004;78(16):8411-20.
2004: Travis J Taylor; David M Knipe
Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8.
Journal of virology 2004;78(11):5856-66.
2004: Martha Simpson-Holley; Joel Baines; Richard J Roller; David M Knipe
Herpes simplex virus 1 U(L)31 and U(L)34 gene products promote the late maturation of viral replication compartments to the nuclear periphery.
Journal of virology 2004;78(11):5591-600.
2004: W James Cook; Martha F Kramer; Russell M Walker; Timothy J Burwell; Holly Ann Holman; Donald M Coen; David M Knipe
Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection.
Virology journal 2004;1():5.
2004: Angela Pearson; David M Knipe; Donald M Coen
ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells.
Journal of virology 2004;78(1):23-32.
2003: Admar Verschoor; Mark Alan Brockman; Mihaela Gadjeva; David M Knipe; Michael C Carroll
Myeloid C3 determines induction of humoral responses to peripheral herpes simplex virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5363-71.
2003: Martha F Kramer; W James Cook; Frederick P Roth; Jia Zhu; Holly Holman; David M Knipe; Donald M Coen
Latent herpes simplex virus infection of sensory neurons alters neuronal gene expression.
Journal of virology 2003;77(17):9533-41.
2003: Susan L Uprichard; David M Knipe
Conformational changes in the herpes simplex virus ICP8 DNA-binding protein coincident with assembly in viral replication structures.
Journal of virology 2003;77(13):7467-76.
2003: Travis J Taylor; Elizabeth E McNamee; Cheryl Day; David M Knipe
Herpes simplex virus replication compartments can form by coalescence of smaller compartments.
Virology 2003;309(2):232-47.
2003: Travis J Taylor; David M Knipe
C-terminal region of herpes simplex virus ICP8 protein needed for intranuclear localization.
Virology 2003;309(2):219-31.
2003: Martha Kramer; Jennifer Riley; Amy Spoering; Donald M Coen; David M Knipe
Effect of immunization on herpes simplex virus type 1 latent infection in the trigeminal ganglion.
Current eye research 2003;26(3-4):185-94.
2002: Mihaela Gadjeva; Admar Verschoor; Mark Alan Brockman; Heather Jezak; Li Ming Shen; David M Knipe; Michael C Carroll
Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5489-95.
2002: Changhong Zhou; David M Knipe
Association of herpes simplex virus type 1 ICP8 and ICP27 proteins with cellular RNA polymerase II holoenzyme.
Journal of virology 2002;76(12):5893-904.
2002: Shun-Hua Chen; Lily Yeh Lee; David A Garber; Priscilla A Schaffer; David M Knipe; Donald M Coen
Neither LAT nor open reading frame P mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virus.
Journal of virology 2002;76(10):4764-72.
2002: Mark Alan Brockman; David M Knipe
Herpes simplex virus vectors elicit durable immune responses in the presence of preexisting host immunity.
Journal of virology 2002;76(8):3678-87.
2002: Travis J Taylor; Mark Alan Brockman; Elizabeth E McNamee; David M Knipe
Herpes simplex virus.
Frontiers in bioscience : a journal and virtual library 2002;7():d752-64.
2001: B Song; K C Yeh; J Liu; David M Knipe
Herpes simplex virus gene products required for viral inhibition of expression of G1-phase functions.
Virology 2001;290(2):320-8.
2001: XJ Da Costa; Lynda A Morrison; David M Knipe
Comparison of different forms of herpes simplex replication-defective mutant viruses as vaccines in a mouse model of HSV-2 genital infection.
Virology 2001;288(2):256-63.
2001: Admar Verschoor; Mark Alan Brockman; David M Knipe; Michael C Carroll
Cutting edge: myeloid complement C3 enhances the humoral response to peripheral viral infection.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(5):2446-51.
2001: S Jean; K M LeVan; B Song; Myron M Levine; David M Knipe
Herpes simplex virus 1 ICP27 is required for transcription of two viral late (gamma 2) genes in infected cells.
Virology 2001;283(2):273-84.
2000: Shun-Hua Chen; David A Garber; Priscilla A Schaffer; David M Knipe; Donald M Coen
Persistent elevated expression of cytokine transcripts in ganglia latently infected with herpes simplex virus in the absence of ganglionic replication or reactivation.
Virology 2000;278(1):207-16.
2000: C A Jones; Travis J Taylor; David M Knipe
Biological properties of herpes simplex virus 2 replication-defective mutant strains in a murine nasal infection model.
Virology 2000;278(1):137-50.
2000: Elizabeth E McNamee; Travis J Taylor; David M Knipe
A dominant-negative herpesvirus protein inhibits intranuclear targeting of viral proteins: effects on DNA replication and late gene expression.
Journal of virology 2000;74(21):10122-31.
2000: XJ Da Costa; Martha F Kramer; Jia Zhu; Mark Alan Brockman; David M Knipe
Construction, phenotypic analysis, and immunogenicity of a UL5/UL29 double deletion mutant of herpes simplex virus 2.
Journal of virology 2000;74(17):7963-71.
2000: C G Murphy; William Lucas; Robert E Means; Susan Czajak; Corrina L Hale; Jeffrey D Lifson; Amitinder Kaur; R Paul Johnson; David M Knipe; Ronald C Desrosiers
Vaccine protection against simian immunodeficiency virus by recombinant strains of herpes simplex virus.
Journal of virology 2000;74(17):7745-54.
2000: B Song; J J Liu; K C Yeh; David M Knipe
Herpes simplex virus infection blocks events in the G1 phase of the cell cycle.
Virology 2000;267(2):326-34.
1999: XJ Da Costa; Mark Alan Brockman; Elisabeth M Alicot; Minghe Ma; MB Fischer; X Zhou; David M Knipe; Michael C Carroll
Humoral response to herpes simplex virus is complement-dependent.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12708-12.
1999: XJ Da Costa; C A Jones; David M Knipe
Immunization against genital herpes with a vaccine virus that has defects in productive and latent infection.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6994-8.
1998: A de Bruyn Kops; Susan L Uprichard; M Chen; David M Knipe
Comparison of the intranuclear distributions of herpes simplex virus proteins involved in various viral functions.
Virology 1998;252(1):162-78.
1998: L E Hann; W James Cook; Susan L Uprichard; David M Knipe; Donald M Coen
The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation.
Journal of virology 1998;72(10):7709-14.
1998: Lynda A Morrison; XJ Da Costa; David M Knipe
Influence of mucosal and parenteral immunization with a replication-defective mutant of HSV-2 on immune responses and protection from genital challenge.
Virology 1998;243(1):178-87.
1998: Martha F Kramer; Shun-Hua Chen; David M Knipe; Donald M Coen
Accumulation of viral transcripts and DNA during establishment of latency by herpes simplex virus.
Journal of virology 1998;72(2):1177-85.
1997: Lynda A Morrison; David M Knipe
Contributions of antibody and T cell subsets to protection elicited by immunization with a replication-defective mutant of herpes simplex virus type 1.
Virology 1997;239(2):315-26.
1997: David A Garber; Priscilla A Schaffer; David M Knipe
A LAT-associated function reduces productive-cycle gene expression during acute infection of murine sensory neurons with herpes simplex virus type 1.
Journal of virology 1997;71(8):5885-93.
1997: XJ Da Costa; Nigel Bourne; Lawrence R Stanberry; David M Knipe
Construction and characterization of a replication-defective herpes simplex virus 2 ICP8 mutant strain and its use in immunization studies in a guinea pig model of genital disease.
Virology 1997;232(1):1-12.
1997: Susan L Uprichard; David M Knipe
Assembly of herpes simplex virus replication proteins at two distinct intranuclear sites.
Virology 1997;229(1):113-25.
1996: J O Brubaker; C M Thompson; Lynda A Morrison; David M Knipe; George R Siber; Robert W Finberg
Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1598-604.
1996: Y M Chen; David M Knipe
A dominant mutant form of the herpes simplex virus ICP8 protein decreases viral late gene transcription.
Virology 1996;221(2):281-90.
1996: Lynda A Morrison; David M Knipe
Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1.
Virology 1996;220(2):402-13.
1996: S Kanangat; J S Babu; David M Knipe; Barry T Rouse
HSV-1-mediated modulation of cytokine gene expression in a permissive cell line: selective upregulation of IL-6 gene expression.
Virology 1996;219(1):295-300.
1996: Susan L Uprichard; David M Knipe
Herpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genes.
Journal of virology 1996;70(3):1969-80.
1996: L M Liptak; Susan L Uprichard; David M Knipe
Functional order of assembly of herpes simplex virus DNA replication proteins into prereplicative site structures.
Journal of virology 1996;70(3):1759-67.
1996: K Xia; Neal A DeLuca; David M Knipe
Analysis of phosphorylation sites of herpes simplex virus type 1 ICP4.
Journal of virology 1996;70(2):1061-71.
1996: K Xia; David M Knipe; Neal A DeLuca
Role of protein kinase A and the serine-rich region of herpes simplex virus type 1 ICP4 in viral replication.
Journal of virology 1996;70(2):1050-60.
1996: J S Babu; J Thomas; S Kanangat; Lynda A Morrison; David M Knipe; Barry T Rouse
Viral replication is required for induction of ocular immunopathology by herpes simplex virus.
Journal of virology 1996;70(1):101-7.
1994: A de Bruyn Kops; David M Knipe
Preexisting nuclear architecture defines the intranuclear location of herpesvirus DNA replication structures.
Journal of virology 1994;68(6):3512-26.
1994: Lynda A Morrison; David M Knipe
Immunization with replication-defective mutants of herpes simplex virus type 1: sites of immune intervention in pathogenesis of challenge virus infection.
Journal of virology 1994;68(2):689-96.
1994: L Nguyen; David M Knipe; Robert W Finberg
Mechanism of virus-induced Ig subclass shifts.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):478-84.
1994: G Davar; Martha F Kramer; D Garber; A L Roca; J K Andersen; W Bebrin; Donald M Coen; M Kosz-Vnenchak; David M Knipe; Xandra O Breakefield
Gene transfer to sensory neurons using herpes virus vectors.
Gene therapy 1994;1 Suppl 1():S24.
1994: G Davar; Martha F Kramer; D Garber; A L Roca; J K Andersen; W Bebrin; Donald M Coen; M Kosz-Vnenchak; David M Knipe; Xandra O Breakefield
Comparative efficacy of expression of genes delivered to mouse sensory neurons with herpes virus vectors.
The Journal of comparative neurology 1994;339(1):3-11.
1993: Jennie Jacobson; K L Ruffner; M Kosz-Vnenchak; Charles B C Hwang; K K Wobbe; David M Knipe; Donald M Coen
Herpes simplex virus thymidine kinase and specific stages of latency in murine trigeminal ganglia.
Journal of virology 1993;67(11):6903-8.
1993: K D Curtin; David M Knipe
Altered properties of the herpes simplex virus ICP8 DNA-binding protein in cells infected with ICP27 mutant viruses.
Virology 1993;196(1):1-14.
1993: M Kosz-Vnenchak; J Jacobson; Donald M Coen; David M Knipe
Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons.
Journal of virology 1993;67(9):5383-93.
1993: M Gao; David M Knipe
Intragenic complementation of herpes simplex virus ICP8 DNA-binding protein mutants.
Journal of virology 1993;67(2):876-85.
1992: L H Nguyen; David M Knipe; Robert W Finberg
Replication-defective mutants of herpes simplex virus (HSV) induce cellular immunity and protect against lethal HSV infection.
Journal of virology 1992;66(12):7067-72.
1992: M Gao; David M Knipe
Distal protein sequences can affect the function of a nuclear localization signal.
Molecular and cellular biology 1992;12(3):1330-9.
1991: J S Gibbs; K Weisshart; Paul Digard; A deBruynKops; David M Knipe; Donald M Coen
Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site.
Molecular and cellular biology 1991;11(9):4786-95.
1991: M Gao; David M Knipe
Potential role for herpes simplex virus ICP8 DNA replication protein in stimulation of late gene expression.
Journal of virology 1991;65(5):2666-75.
1991: M Bush; D R Yager; M Gao; K Weisshart; A I Marcy; Donald M Coen; David M Knipe
Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein.
Journal of virology 1991;65(3):1082-9.
1990: M Kosz-Vnenchak; Donald M Coen; David M Knipe
Restricted expression of herpes simplex virus lytic genes during establishment of latent infection by thymidine kinase-negative mutant viruses.
Journal of virology 1990;64(11):5396-402.
1990: S A Rice; David M Knipe
Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.
Journal of virology 1990;64(4):1704-15.
1989: M Gao; David M Knipe
Genetic evidence for multiple nuclear functions of the herpes simplex virus ICP8 DNA-binding protein.
Journal of virology 1989;63(12):5258-67.
1989: S A Rice; L S Su; David M Knipe
Herpes simplex virus alpha protein ICP27 possesses separable positive and negative regulatory activities.
Journal of virology 1989;63(8):3399-407.
1989: D A Leib; C L Bogard; M Kosz-Vnenchak; K A Hicks; Donald M Coen; David M Knipe; Priscilla A Schaffer
A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency.
Journal of virology 1989;63(7):2893-900.
1989: Donald M Coen; M Kosz-Vnenchak; Jennie Jacobson; D A Leib; C L Bogard; Priscilla A Schaffer; Kenneth L Tyler; David M Knipe
Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4736-40.
1989: L Su; David M Knipe
Herpes simplex virus alpha protein ICP27 can inhibit or augment viral gene transactivation.
Virology 1989;170(2):496-504.
1989: D A Leib; Donald M Coen; C L Bogard; K A Hicks; D R Yager; David M Knipe; Kenneth L Tyler; Priscilla A Schaffer
Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.
Journal of virology 1989;63(2):759-68.
1989: David M Knipe
The role of viral and cellular nuclear proteins in herpes simplex virus replication.
Advances in virus research 1989;37():85-123.
1988: A de Bruyn Kops; David M Knipe
Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein.
Cell 1988;55(5):857-68.
1988: S A Rice; David M Knipe
Gene-specific transactivation by herpes simplex virus type 1 alpha protein ICP27.
Journal of virology 1988;62(10):3814-23.
1988: M Gao; J Bouchey; K Curtin; David M Knipe
Genetic identification of a portion of the herpes simplex virus ICP8 protein required for DNA-binding.
Virology 1988;163(2):319-29.