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Markus Knöferl

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Mario Perl; Jörg Thomas; Philipp Kellermann; Markus W Knöferl; Dapeng Lu; Alfred Ayala; Max G Bachem; Sonja Braumüller; Stephanie Denk; Florian Gebhard; Christoph Hohmann; Markus Huber-Lang
Role of activated neutrophils in chest trauma-induced septic acute lung injury.
Daniel H Seitz; Heinrich A Veltkamp; Ulrich Wachter; Florian Daniel Wagner; Katja Wagner; Shaoxia Zhou; S Bäder; Sonja T Braumüller; Enrico Calzia; Janine S Fröba; Florian Gebhard; Markus Huber-Lang; Ulrike Niesler; Annette Palmer; Peter Radermacher; Markus W Knöferl
Inhaled hydrogen sulfide induces suspended animation, but does not alter the inflammatory response after blunt chest trauma.
Mario Perl; Alfred Ayala; Max G Bachem; Sonja Braumüller; Florian Gebhard; Hans-Jürgen Gross; Markus Huber-Lang; Manuel Kieninger; Markus W Knöferl
Divergent effects of activated neutrophils on inflammation, Kupffer cell/splenocyte activation, and lung injury following blunt chest trauma.

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All Publications

2012: Mario Perl; Jörg Thomas; Philipp Kellermann; Markus W Knöferl; Dapeng Lu; Alfred Ayala; Max G Bachem; Sonja Braumüller; Stephanie Denk; Florian Gebhard; Christoph Hohmann; Markus Huber-Lang
Role of activated neutrophils in chest trauma-induced septic acute lung injury.
Shock (Augusta, Ga.) 2012;38(1):98-106.
2012: Daniel H Seitz; Heinrich A Veltkamp; Ulrich Wachter; Florian Daniel Wagner; Katja Wagner; Shaoxia Zhou; S Bäder; Sonja T Braumüller; Enrico Calzia; Janine S Fröba; Florian Gebhard; Markus Huber-Lang; Ulrike Niesler; Annette Palmer; Peter Radermacher; Markus W Knöferl
Inhaled hydrogen sulfide induces suspended animation, but does not alter the inflammatory response after blunt chest trauma.
Shock (Augusta, Ga.) 2012;37(2):197-204.
2012: Mario Perl; Alfred Ayala; Max G Bachem; Sonja Braumüller; Florian Gebhard; Hans-Jürgen Gross; Markus Huber-Lang; Manuel Kieninger; Markus W Knöferl
Divergent effects of activated neutrophils on inflammation, Kupffer cell/splenocyte activation, and lung injury following blunt chest trauma.
Shock (Augusta, Ga.) 2012;37(2):210-8.
2011: Daniel H Seitz; Shaoxia Zhou; Ulrike Niesler; Annette Palmer; Anne Rittlinger; Sonja T Braumüller; Janine S Fröba; Florian Gebhard; Vera Heidemann; Markus W Knöferl
Alveolar macrophage phagocytosis is enhanced after blunt chest trauma and alters the posttraumatic mediator release.
Shock (Augusta, Ga.) 2011;36(6):621-7.
2011: Florian Daniel Wagner; Sandra Weber; Pierre Asfar; Enrico Calzia; Florian Gebhard; Michael Georgieff; Markus Huber-Lang; Markus W Knöferl; Oscar McCook; Peter Möller; Peter Radermacher; Angelika Scheuerle; Daniel H Seitz; Bettina Stahl; Csaba Szabó; Jörg Thomas; Katja Wagner
Cardiopulmonary, histologic, and inflammatory effects of intravenous Na2S after blunt chest trauma-induced lung contusion in mice.
The Journal of trauma 2011;71(6):1659-67.
2011: Daniel H Seitz; Annette Palmer; Ulrike Niesler; Sonja T Braumüller; Simon Bauknecht; Florian Gebhard; Markus W Knöferl
Altered expression of Fas receptor on alveolar macrophages and inflammatory effects of soluble Fas ligand following blunt chest trauma.
Shock (Augusta, Ga.) 2011;35(6):610-7.
2011: Florian Daniel Wagner; Katja Wagner; Sandra Weber; Bettina Stahl; Markus W Knöferl; Markus Huber-Lang; Daniel H Seitz; Pierre Asfar; Enrico Calzia; Uwe Senftleben; Florian Gebhard; Michael Georgieff; Peter Radermacher; Vladislava Hysa
Inflammatory effects of hypothermia and inhaled H2S during resuscitated, hyperdynamic murine septic shock.
Shock (Augusta, Ga.) 2011;35(4):396-402.
2011: Ulrich C Liener; Mario Perl; Markus Huber-Lang; Daniel H Seitz; Uwe B Brückner; Florian Gebhard; Markus W Knöferl
Is the function of alveolar macrophages altered following blunt chest trauma?
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 2011;396(2):251-9.
2011: Katja Wagner; Pierre Asfar; Enrico Calzia; Michael Georgieff; Markus W Knöferl; Peter Radermacher
Of mice and men (and sheep, swine etc.): the intriguing hemodynamic and metabolic effects of hydrogen sulfide (H2S).
Critical care (London, England) 2011;15(2):146.
2011: Daniel H Seitz; Mario Perl; Ulrich C Liener; Björn Tauchmann; Sonja T Braumüller; Uwe B Brückner; Florian Gebhard; Markus W Knöferl
Inflammatory alterations in a novel combination model of blunt chest trauma and hemorrhagic shock.
The Journal of trauma 2011;70(1):189-96.
2010: Daniel H Seitz; Ulrike Niesler; Annette Palmer; Michael Sulger; Sonja T Braumüller; Mario Perl; Florian Gebhard; Markus W Knöferl
Blunt chest trauma induces mediator-dependent monocyte migration to the lung.
Critical care medicine 2010;38(9):1852-9.
2010: Katja Baumgart; Florian Daniel Wagner; Michael Gröger; Sandra Weber; Eberhard Barth; Josef A Vogt; Ulrich Wachter; Markus Huber-Lang; Markus W Knöferl; Gerd Albuszies; Michael Georgieff; Pierre Asfar; Csaba Szabó; Enrico Calzia; Peter Radermacher; Vladislava Simkova
Cardiac and metabolic effects of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice.
Critical care medicine 2010;38(2):588-95.
2008: Daniel H Seitz; Mario Perl; Stefanie Mangold; Anne Neddermann; Sonja T Braumüller; Shaoixa Zhou; Max G Bachem; Markus Huber-Lang; Markus W Knöferl
Pulmonary contusion induces alveolar type 2 epithelial cell apoptosis: role of alveolar macrophages and neutrophils.
Shock (Augusta, Ga.) 2008;30(5):537-44.
2006: Ulrich C Liener; Stefan Sauerland; Markus W Knöferl; C Bartl; C Riepl; Lothar Kinzl; Florian Gebhard
[Emergency surgery for chest injuries in the multiply injured: a systematic review].
Der Unfallchirurg 2006;109(6):447-52.
2006: Mario Perl; Florian Gebhard; Sonja Braumüller; Björn Tauchmann; Uwe B Brückner; Lothar Kinzl; Markus W Knöferl
The pulmonary and hepatic immune microenvironment and its contribution to the early systemic inflammation following blunt chest trauma.
Critical care medicine 2006;34(4):1152-9.
2005: Mario Perl; Florian Gebhard; Uwe B Brückner; Alfred Ayala; Sonja Braumüller; Christian Büttner; Lothar Kinzl; Markus W Knöferl
Pulmonary contusion causes impairment of macrophage and lymphocyte immune functions and increases mortality associated with a subsequent septic challenge.
Critical care medicine 2005;33(6):1351-8.
2004: Markus W Knöferl; Ulrich C Liener; Mario Perl; Uwe B Brückner; Lothar Kinzl; Florian Gebhard
Blunt chest trauma induces delayed splenic immunosuppression.
Shock (Augusta, Ga.) 2004;22(1):51-6.
2003: Ulrich C Liener; Markus W Knöferl; Jörn Sträter; Thomas F E Barth; Eva-Marie Pauser; Andreas K Nüssler; Lothar Kinzl; Uwe B Brückner; Florian Gebhard
Induction of apoptosis following blunt chest trauma.
Shock (Augusta, Ga.) 2003;20(6):511-6.
2003: Markus W Knöferl; Ulrich C Liener; Daniel H Seitz; Mario Perl; Uwe B Brückner; Lothar Kinzl; Florian Gebhard
Cardiopulmonary, histological, and inflammatory alterations after lung contusion in a novel mouse model of blunt chest trauma.
Shock (Augusta, Ga.) 2003;19(6):519-25.
2003: Mario Perl; Florian Gebhard; Markus W Knöferl; Max G Bachem; Hans-Jürgen Gross; Lothar Kinzl; Wolf Strecker
The pattern of preformed cytokines in tissues frequently affected by blunt trauma.
Shock (Augusta, Ga.) 2003;19(4):299-304.
2003: Markus W Knöferl; Martin K Angele; Martin G Schwacha; T S Anantha Samy; Kirby I Bland; Irshad H Chaudry
Immunoprotection in proestrus females following trauma-hemorrhage: the pivotal role of estrogen receptors.
Cellular immunology 2003;222(1):27-34.
2002: Markus W Knöferl; Martin G Schwacha; Doraid Jarrar; Martin K Angele; Keith Fragoza; Kirby I Bland; Irshad H Chaudry
Estrogen pretreatment protects males against hypoxia-induced immune depression.
American journal of physiology. Cell physiology 2002;282(5):C1087-92.
2002: Markus W Knöferl; Martin K Angele; Martin G Schwacha; Kirby I Bland; Irshad H Chaudry
Preservation of splenic immune functions by female sex hormones after trauma-hemorrhage.
Critical care medicine 2002;30(4):888-93.
2002: Ulrich C Liener; Uwe B Brückner; Markus W Knöferl; Gerald Steinbach; Lothar Kinzl; Florian Gebhard
Chemokine activation within 24 hours after blunt accident trauma.
Shock (Augusta, Ga.) 2002;17(3):169-72.
2002: Markus W Knöferl; Martin K Angele; Michael D Diodato; Martin G Schwacha; Alfred Ayala; William G Cioffi; Kirby I Bland; Irshad H Chaudry
Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis.
Annals of surgery 2002;235(1):105-12.
2001: Markus W Knöferl; Michael D Diodato; Martin G Schwacha; William G Cioffi; Kirby I Bland; Irshad H Chaudry
Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis.
Shock (Augusta, Ga.) 2001;16(6):479-83.
2001: Martin K Angele; Markus W Knöferl; Alfred Ayala; Kirby I Bland; Irshad H Chaudry
Testosterone and estrogen differently effect Th1 and Th2 cytokine release following trauma-haemorrhage.
Cytokine 2001;16(1):22-30.
2001: Markus W Knöferl; Doraid Jarrar; Martin K Angele; Alfred Ayala; Martin G Schwacha; Kirby I Bland; Irshad H Chaudry
17 beta-Estradiol normalizes immune responses in ovariectomized females after trauma-hemorrhage.
American journal of physiology. Cell physiology 2001;281(4):C1131-8.
2001: T S Anantha Samy; Markus W Knöferl; Rui Zheng; Martin G Schwacha; Kirby I Bland; Irshad H Chaudry
Divergent immune responses in male and female mice after trauma-hemorrhage: dimorphic alterations in T lymphocyte steroidogenic enzyme activities.
Endocrinology 2001;142(8):3519-29.
2001: Michael D Diodato; Markus W Knöferl; Martin G Schwacha; Kirby I Bland; Irshad H Chaudry
Gender differences in the inflammatory response and survival following haemorrhage and subsequent sepsis.
Cytokine 2001;14(3):162-9.
2000: Martin G Schwacha; Markus W Knöferl; Irshad H Chaudry
Does burn wound excision after thermal injury attenuate subsequent macrophage hyperactivity and immunosuppression?
Shock (Augusta, Ga.) 2000;14(6):623-8.
2000: Markus W Knöferl; Doraid Jarrar; Martin G Schwacha; Martin K Angele; William G Cioffi; K I Bland; I H Chaudry
Severe hypoxemia in the absence of blood loss causes a gender dimorphic immune response.
American journal of physiology. Cell physiology 2000;279(6):C2004-10.
2000: Doraid Jarrar; Ping Wang; Markus W Knöferl; Zheng F Ba; William G Cioffi; Kirby I Bland; Irshad H Chaudry
Does early infusion of red blood cells after trauma and hemorrhage improve organ functions?
Critical care medicine 2000;28(10):3498-504.
2000: Martin K Angele; F Fitzal; N Smail; Markus W Knöferl; Martin G Schwacha; Alfred Ayala; Ping Wang; Irshad H Chaudry
L-arginine attenuates trauma-hemorrhage-induced liver injury.
Critical care medicine 2000;28(9):3242-8.
2000: Doraid Jarrar; Ping Wang; Markus W Knöferl; Joachim F Kuebler; William G Cioffi; Kirby I Bland; Irshad H Chaudry
Insight into the mechanism by which estradiol improves organ functions after trauma-hemorrhage.
Surgery 2000;128(2):246-52.
2000: Markus W Knöferl; Martin K Angele; A Ayala; W G Cioffi; K I Bland; Irshad H Chaudry
Insight into the mechanism by which metoclopramide improves immune functions after trauma-hemorrhage.
American journal of physiology. Cell physiology 2000;279(1):C72-80.
2000: Markus W Knöferl; Michael D Diodato; Martin K Angele; Alfred Ayala; William G Cioffi; Kirby I Bland; Irshad H Chaudry
Do female sex steroids adversely or beneficially affect the depressed immune responses in males after trauma-hemorrhage?
Archives of surgery (Chicago, Ill. : 1960) 2000;135(4):425-33.
2000: Doraid Jarrar; Ping Wang; Grace Y Song; Markus W Knöferl; William G Cioffi; Kirby I Bland; Irshad H Chaudry
Metoclopramide: a novel adjunct for improving cardiac and hepatocellular functions after trauma-hemorrhage.
American journal of physiology. Endocrinology and metabolism 2000;278(1):E90-5.
1999: Martin K Angele; Markus W Knöferl; Alfred Ayala; Jorge E Albina; William G Cioffi; Kirby I Bland; Irshad H Chaudry
Trauma-hemorrhage delays wound healing potentially by increasing pro-inflammatory cytokines at the wound site.
Surgery 1999;126(2):279-85.
1999: Martin K Angele; Markus W Knöferl; Martin G Schwacha; Alfred Ayala; William G Cioffi; Kirby I Bland; Irshad H Chaudry
Sex steroids regulate pro- and anti-inflammatory cytokine release by macrophages after trauma-hemorrhage.
The American journal of physiology 1999;277(1 Pt 1):C35-42.
1999: Martin K Angele; Markus W Knöferl; Martin G Schwacha; Alfred Ayala; Kirby I Bland; William G Cioffi; S L Josephson; Irshad H Chaudry
Hemorrhage decreases macrophage inflammatory protein 2 and interleukin-6 release: a possible mechanism for increased wound infection.
Annals of surgery 1999;229(5):651-60; discussion 660-1.
1999: Markus W Knöferl; Martin K Angele; Alfred Ayala; William G Cioffi; Kirby I Bland; Irshad H Chaudry
Do different rates of fluid resuscitation adversely or beneficially influence immune responses after trauma-hemorrhage?
The Journal of trauma 1999;46(1):23-33.
1999: Martin K Angele; N Smail; Markus W Knöferl; Alfred Ayala; William G Cioffi; Irshad H Chaudry
L-Arginine restores splenocyte functions after trauma and hemorrhage potentially by improving splenic blood flow.
The American journal of physiology 1999;276(1 Pt 1):C145-51.