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Jürgen Knop

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Andrea Tuettenberg; Eva Huter; Mario Hubo; Julia Horn; Jürgen Knop; Bodo Grimbacher; Richard A Kroczek; Sabine Stoll; Helmut Jonuleit
The role of ICOS in directing T cell responses: ICOS-dependent induction of T cell anergy by tolerogenic dendritic cells.
Peri Caucig; Susanne Lescau; Jürgen Knop; Marcus Maurer; Esther Von Stebut
Interleukin-2 immediate type hypersensitivity?
Ingo Böttcher; Iris Bellinghausen; Bettina König; Jürgen Knop; Joachim Saloga
Different regulation of T helper 1- and T helper 2-promoting cytokine signalling factors in human dendritic cells after exposure to protein versus contact allergens.

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2009: Andrea Tuettenberg; Eva Huter; Mario Hubo; Julia Horn; Jürgen Knop; Bodo Grimbacher; Richard A Kroczek; Sabine Stoll; Helmut Jonuleit
The role of ICOS in directing T cell responses: ICOS-dependent induction of T cell anergy by tolerogenic dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3349-56.
2008: Peri Caucig; Susanne Lescau; Jürgen Knop; Marcus Maurer; Esther Von Stebut
Interleukin-2 immediate type hypersensitivity?
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2008;6(11):956-8.
2008: Ingo Böttcher; Iris Bellinghausen; Bettina König; Jürgen Knop; Joachim Saloga
Different regulation of T helper 1- and T helper 2-promoting cytokine signalling factors in human dendritic cells after exposure to protein versus contact allergens.
Immunology 2008;123(1):139-44.
2007: Bettina König; Arnd Petersen; Iris Bellinghausen; Ingo Böttcher; Wolf-Meinhard Becker; Jürgen Knop; Joachim Saloga
Human dendritic cells transfected with allergen-DNA stimulate specific immunoglobulin G4 but not specific immunoglobulin E production of autologous B cells from atopic individuals in vitro.
Immunology 2007;122(2):239-46.
2007: Jan Kubach; Petra Lutter; Tobias Bopp; Sabine Stoll; Christian Becker; Eva Huter; Christoph Richter; Petra Weingarten; Tobias Warger; Jürgen Knop; Stefan Müllner; John Wijdenes; Hansjörg Schild; Edgar Schmitt; Helmut Jonuleit
Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function.
Blood 2007;110(5):1550-8.
2007: Henric S Adler; Sebastian Kubsch; Edith Graulich; Stephan Ludwig; Jürgen Knop; Kerstin Steinbrink
Activation of MAP kinase p38 is critical for the cell-cycle-controlled suppressor function of regulatory T cells.
Blood 2007;109(10):4351-9.
2007: Christian Becker; Jan Kubach; John Wijdenes; Jürgen Knop; Helmut Jonuleit
CD4-mediated functional activation of human CD4+CD25+ regulatory T cells.
European journal of immunology 2007;37(5):1217-23.
2007: Matthias Bros; Frank Jährling; Andrea Renzing; Nadine Wiechmann; Ngoc-Anh Dang; Arne Sutter; Ralf Ross; Jürgen Knop; Stephan Sudowe; Angelika B Reske-Kunz
A newly established murine immature dendritic cell line can be differentiated into a mature state, but exerts tolerogenic function upon maturation in the presence of glucocorticoid.
Blood 2007;109(9):3820-9.
2007: Andrea Tuettenberg; Edgar Schmitt; Jürgen Knop; Helmut Jonuleit
Dendritic cell-based immunotherapy of malignant melanoma: success and limitations.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2007;5(3):190-6.
2007: Andrea Tuettenberg; Stephan Koelsch; Jürgen Knop; Helmut Jonuleit
Oxymetazoline modulates proinflammatory cytokines and the T-cell stimulatory capacity of dendritic cells.
Experimental dermatology 2007;16(3):171-8.
2007: Karina Gisch; Nadine Gehrke; Matthias Bros; Christina Priesmeyer; Jürgen Knop; Angelika B Reske-Kunz; Stephan Sudowe
Formalin-fixed Staphylococcus aureus particles prevent allergic sensitization in a murine model of type I allergy.
International archives of allergy and immunology 2007;144(3):183-96.
2006: Iris Bellinghausen; Bettina König; Ingo Böttcher; Jürgen Knop; Joachim Saloga
Inhibition of human allergic T-helper type 2 immune responses by induced regulatory T cells requires the combination of interleukin-10-treated dendritic cells and transforming growth factor-beta for their induction.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2006;36(12):1546-55.
2006: Marcus Maurer; Susanna Lopez Kostka; Frank Siebenhaar; Katharina Moelle; Martin Metz; Jürgen Knop; Esther Von Stebut
Skin mast cells control T cell-dependent host defense in Leishmania major infections.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(14):2460-7.
2006: Iris Bellinghausen; Jürgen Knop; Joachim Saloga
[Mechanisms of specific immunotherapy].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2006;57(10):855-9.
2006: Susanna Lopez Kostka; Jürgen Knop; Abdo Konur; Mark C Udey; Esther Von Stebut
Distinct roles for IL-1 receptor type I signaling in early versus established Leishmania major infections.
The Journal of investigative dermatology 2006;126(7):1582-9.
2006: Benno Weigmann; Elizabeth R Jarman; Stephan Sudowe; Matthias Bros; Jürgen Knop; Angelika B Reske-Kunz
Induction of regulatory T cells by leflunomide in a murine model of contact allergen sensitivity.
The Journal of investigative dermatology 2006;126(7):1524-33.
2006: Andrea Tuettenberg; Christian Becker; Eva Huter; Jürgen Knop; Alexander H Enk; Helmut Jonuleit
Induction of strong and persistent MelanA/MART-1-specific immune responses by adjuvant dendritic cell-based vaccination of stage II melanoma patients.
International journal of cancer. Journal international du cancer 2006;118(10):2617-27.
2006: Wolfgang Seidel-Guyenot; Sylwia Perschon; Natascha Dechant; Ruth Alt; Jürgen Knop; Kerstin Steinbrink
Low zone tolerance induced by systemic application of allergens inhibits Tc1-mediated skin inflammation.
The Journal of allergy and clinical immunology 2006;117(5):1170-7.
2006: Florian Woelbing; Susanna Lopez Kostka; Katharina Moelle; Yasmine Belkaid; Cord Sunderkoetter; Sjef Verbeek; Ari Waisman; Axel P Nigg; Jürgen Knop; Mark C Udey; Esther Von Stebut
Uptake of Leishmania major by dendritic cells is mediated by Fcgamma receptors and facilitates acquisition of protective immunity.
The Journal of experimental medicine 2006;203(1):177-88.
2006: Iris Bellinghausen; Stephan Sudowe; Bettina König; Angelika B Reske-Kunz; Jürgen Knop; Joachim Saloga
Interleukin-10-treated dendritic cells do not inhibit Th2 immune responses in ovalbumin/alum-sensitized mice.
International archives of allergy and immunology 2006;141(1):61-9.
2005: Iris Bellinghausen; Bettina König; Ingo Böttcher; Jürgen Knop; Joachim Saloga
Regulatory activity of human CD4 CD25 T cells depends on allergen concentration, type of allergen and atopy status of the donor.
Immunology 2005;116(1):103-11.
2004: Wolfgang Seidel-Guyenot; Ruth Alt; Sylwia Perschon; Jürgen Knop; Kerstin Steinbrink
B cells are not required for T cell priming in low zone tolerance to contact allergens and contact hypersensitivity.
European journal of immunology 2004;34(11):3082-90.
2004: Martin Metz; Vladimir A Botchkarev; Natalia V Botchkareva; Pia Welker; Desmond J Tobin; Jürgen Knop; Marcus Maurer; Ralf Paus
Neurotrophin-3 regulates mast cell functions in neonatal mouse skin.
Experimental dermatology 2004;13(5):273-81.
2004: Michael Stassen; Sabine Fondel; Tobias Bopp; Christoph Richter; Christian Müller; Jan Kubach; Christian Becker; Jürgen Knop; Alexander H Enk; Steffen Schmitt; Edgar Schmitt; Helmut Jonuleit
Human CD25+ regulatory T cells: two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4+ T helper cells.
European journal of immunology 2004;34(5):1303-11.
2004: Iris Bellinghausen; Bettina Klostermann; Ingo Böttcher; Jürgen Knop; Joachim Saloga
Importance of the inducible costimulator molecule for the induction of allergic immune responses and its decreased expression on T helper cells after venom immunotherapy.
Immunology 2004;112(1):80-6.
2004: Bettina Klostermann; Iris Bellinghausen; Ingo Böttcher; Arnd Petersen; Wolf-Meinhard Becker; Jürgen Knop; Joachim Saloga
Modification of the human allergic immune response by allergen-DNA-transfected dendritic cells in vitro.
The Journal of allergy and clinical immunology 2004;113(2):327-33.
2004: Thomas M Proebstle; Frank Krummenauer; Doendue Gül; Jürgen Knop
Nonocclusion and early reopening of the great saphenous vein after endovenous laser treatment is fluence dependent.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2004;30(2 Pt 1):174-8.
2004: Andrea Tuettenberg; Helmut Jonuleit; Thomas Tüting; Jürgen Brück; Volker Biermann; Stefan Kochanek; Jürgen Knop; Alexander H Enk
Early adenoviral gene expression mediates immunosuppression by transduced dendritic cell (DC): implications for immunotherapy using genetically modified DC.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1524-30.
2003: Karsten Mahnke; Jürgen Knop; Alexander H Enk
Induction of tolerogenic DCs: 'you are what you eat'.
Trends in immunology 2003;24(12):646-51.
2003: Stefanie Bruchhausen; Sabine Zahn; Elke Valk; Jürgen Knop; Detlef Becker
Thiol antioxidants block the activation of antigen-presenting cells by contact sensitizers.
The Journal of investigative dermatology 2003;121(5):1039-44.
2003: Thomas M Proebstle; Doendue Gül; HA Lehr; Alexandra Kargl; Jürgen Knop
Infrequent early recanalization of greater saphenous vein after endovenous laser treatment.
Journal of vascular surgery 2003;38(3):511-6.
2003: Marcus Maurer; Wolfgang Seidel-Guyenot; Martin Metz; Jürgen Knop; Kerstin Steinbrink
Critical role of IL-10 in the induction of low zone tolerance to contact allergens.
The Journal of clinical investigation 2003;112(3):432-9.
2003: Karsten Mahnke; Yingjie Qian; Jürgen Knop; Alexander H Enk
Dendritic cells, engineered to secrete a T-cell receptor mimic peptide, induce antigen-specific immunosuppression in vivo.
Nature biotechnology 2003;21(8):903-8.
2003: Esther Von Stebut; Jan Ehrchen; Yasmine Belkaid; Susanna Lopez Kostka; Katharina Molle; Jürgen Knop; Cord Sunderkotter; Mark C Udey
Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice.
The Journal of experimental medicine 2003;198(2):191-9.
2003: Sebastian Kubsch; Edith Graulich; Jürgen Knop; Kerstin Steinbrink
Suppressor activity of anergic T cells induced by IL-10-treated human dendritic cells: association with IL-2- and CTLA-4-dependent G1 arrest of the cell cycle regulated by p27Kip1.
European journal of immunology 2003;33(7):1988-97.
2003: Karsten Mahnke; Yingjie Qian; Jürgen Knop; Alexander H Enk
Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells.
Blood 2003;101(12):4862-9.
2003: Ralf Ross; Stephan Sudowe; J Beisner; Xiao-Lan Ross; Isis Ludwig-Portugall; Julia Steitz; Thomas Tüting; Jürgen Knop; Angelika B Reske-Kunz
Transcriptional targeting of dendritic cells for gene therapy using the promoter of the cytoskeletal protein fascin.
Gene therapy 2003;10(12):1035-40.
2003: Iris Bellinghausen; Bettina Klostermann; Jürgen Knop; Joachim Saloga
Human CD4+CD25+ T cells derived from the majority of atopic donors are able to suppress TH1 and TH2 cytokine production.
The Journal of allergy and clinical immunology 2003;111(4):862-8.
2003: Thomas M Proebstle; Doendue Gül; Alexandra Kargl; Jürgen Knop
Endovenous laser treatment of the lesser saphenous vein with a 940-nm diode laser: early results.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2003;29(4):357-61.
2003: Ignaz Wessler; Torsten Reinheimer; Heinz Kilbinger; Fernando Bittinger; Charles James Kirkpatrick; Joachim Saloga; Jürgen Knop
Increased acetylcholine levels in skin biopsies of patients with atopic dermatitis.
Life sciences 2003;72(18-19):2169-72.
2003: Andrea Tuettenberg; Helmut Jonuleit; Thomas Tüting; Jürgen Brück; Jürgen Knop; Alexander H Enk
Priming of T cells with Ad-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor-specific CD8+ T cells: implications for an efficient vaccination strategy.
Gene therapy 2003;10(3):243-50.
2003: Iris Bellinghausen; Pia Brand; Ingo Böttcher; Bettina Klostermann; Jürgen Knop; Joachim Saloga
Production of interleukin-13 by human dendritic cells after stimulation with protein allergens is a key factor for induction of T helper 2 cytokines and is associated with activation of signal transducer and activator of transcription-6.
Immunology 2003;108(2):167-76.
2003: Detlef Becker; Elke Valk; Sabine Zahn; Pia Brand; Jürgen Knop
Coupling of contact sensitizers to thiol groups is a key event for the activation of monocytes and monocyte-derived dendritic cells.
The Journal of investigative dermatology 2003;120(2):233-8.
2003: Kerstin Steinbrink; Jürgen Knop
[Significance of immunologic tolerance in dermatology].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2003;54(1):45-52.
2003: Esther Von Stebut; Martin Metz; Genevieve Milon; Jürgen Knop; Marcus Maurer
Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1alpha /beta released from neutrophils recruited by mast cell-derived TNFalpha.
Blood 2003;101(1):210-5.
2002: Thomas M Proebstle; V Schneiders; Jürgen Knop
Gravimetrically controlled efficacy of subcorial curettage: a prospective study for treatment of axillary hyperhidrosis.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2002;28(11):1022-6.
2002: Gabriele Müller; Anke Müller; Thomas Tüting; Kerstin Steinbrink; Joachim Saloga; Claudia Szalma; Jürgen Knop; Alexander H Enk
Interleukin-10-treated dendritic cells modulate immune responses of naive and sensitized T cells in vivo.
The Journal of investigative dermatology 2002;119(4):836-41.
2002: Thomas M Proebstle; S Bethge; Sven-Erik Barnstedt; Alexandra Kargl; Jürgen Knop; G Sattler
Subfascial endoscopic perforator surgery with tumescent local anesthesia.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2002;28(8):689-93.
2002: Helmut Jonuleit; Edgar Schmitt; Hacer Kakirman; Michael Stassen; Jürgen Knop; Alexander H Enk
Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells.
The Journal of experimental medicine 2002;196(2):255-60.
2002: Pia Brand; Sibylle Plochmann; Elke Valk; Sabine Zahn; Joachim Saloga; Jürgen Knop; Detlef Becker
Activation and translocation of p38 mitogen-activated protein kinase after stimulation of monocytes with contact sensitizers.
The Journal of investigative dermatology 2002;119(1):99-106.
2002: Thomas M Proebstle; M Sandhofer; Alexandra Kargl; Doendue Gül; W Rother; Jürgen Knop; HA Lehr
Thermal damage of the inner vein wall during endovenous laser treatment: key role of energy absorption by intravascular blood.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2002;28(7):596-600.
2002: Elke Valk; Sabine Zahn; Jürgen Knop; Detlef Becker
JAK/STAT pathways are not involved in the direct activation of antigen-presenting cells by contact sensitizers.
Archives of dermatological research 2002;294(4):163-7.
2002: Rudolf E Schopf; Holger Aust; Jürgen Knop
Treatment of psoriasis with the chimeric monoclonal antibody against tumor necrosis factor alpha, infliximab.
Journal of the American Academy of Dermatology 2002;46(6):886-91.
2002: Thomas M Proebstle; HA Lehr; Alexandra Kargl; Christine Espinola-Klein; W Rother; S Bethge; Jürgen Knop
Endovenous treatment of the greater saphenous vein with a 940-nm diode laser: thrombotic occlusion after endoluminal thermal damage by laser-generated steam bubbles.
Journal of vascular surgery 2002;35(4):729-36.
2002: Kerstin Steinbrink; Edith Graulich; Sebastian Kubsch; Jürgen Knop; Alexander H Enk
CD4(+) and CD8(+) anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity.
Blood 2002;99(7):2468-76.
2002: Julia Steitz; Jürgen Brück; Andrea Gambotto; Jürgen Knop; Thomas Tüting
Genetic immunization with a melanocytic self-antigen linked to foreign helper sequences breaks tolerance and induces autoimmunity and tumor immunity.
Gene therapy 2002;9(3):208-13.
2002: Stephan Sudowe; Evelyn Montermann; Julia Steitz; Thomas Tüting; Jürgen Knop; Angelika B Reske-Kunz
Efficacy of recombinant adenovirus as vector for allergen gene therapy in a mouse model of type I allergy.
Gene therapy 2002;9(2):147-56.
2001: Julia Steitz; Jürgen Brück; Julia Lenz; Jürgen Knop; Thomas Tüting
Depletion of CD25(+) CD4(+) T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon alpha-induced, CD8(+) T-cell-dependent immune defense of B16 melanoma.
Cancer research 2001;61(24):8643-6.
2001: Iris Bellinghausen; Jürgen Knop; Joachim Saloga
The role of interleukin 10 in the regulation of allergic immune responses.
International archives of allergy and immunology 2001;126(2):97-101.
2001: Julia Steitz; Jürgen Brück; Jürgen Knop; Thomas Tüting
Adenovirus-transduced dendritic cells stimulate cellular immunity to melanoma via a CD4(+) T cell-dependent mechanism.
Gene therapy 2001;8(16):1255-63.
2001: Iris Bellinghausen; U Brand; Kerstin Steinbrink; Alexander H Enk; Jürgen Knop; Joachim Saloga
Inhibition of human allergic T-cell responses by IL-10-treated dendritic cells: differences from hydrocortisone-treated dendritic cells.
The Journal of allergy and clinical immunology 2001;108(2):242-9.
2001: Helmut Jonuleit; A Giesecke-Tuettenberg; Thomas Tüting; B Thurner-Schuler; Tor Stuge; L Paragnik; A Kandemir; Peter P Lee; Gerold Schuler; Jürgen Knop; Alexander H Enk
A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection.
International journal of cancer. Journal international du cancer 2001;93(2):243-51.
2001: Helmut Jonuleit; Edgar Schmitt; Michael Stassen; Andrea Tuettenberg; Jürgen Knop; Alexander H Enk
Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood.
The Journal of experimental medicine 2001;193(11):1285-94.
2000: A H Enk; Jürgen Knop
T cell receptor mimic peptides and their potential application in T-cell-mediated disease.
International archives of allergy and immunology 2000;123(4):275-81.
2000: Helmut Jonuleit; Edgar Schmitt; Gerold Schuler; Jürgen Knop; Alexander H Enk
Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells.
The Journal of experimental medicine 2000;192(9):1213-22.
2000: Ralf Ross; Helmut Jonuleit; Matthias Bros; Xiao-Lan Ross; S Yamashiro; F Matsumura; Alexander H Enk; Jürgen Knop; Angelika B Reske-Kunz
Expression of the actin-bundling protein fascin in cultured human dendritic cells correlates with dendritic morphology and cell differentiation.
The Journal of investigative dermatology 2000;115(4):658-63.
2000: Kerstin Steinbrink; L Paragnik; Helmut Jonuleit; Thomas Tüting; Jürgen Knop; Alexander H Enk
Induction of dendritic cell maturation and modulation of dendritic cell-induced immune responses by prostaglandins.
Archives of dermatological research 2000;292(9):437-45.
2000: Helmut Jonuleit; A Giesecke; A Kandemir; L Paragnik; Jürgen Knop; Alexander H Enk
Induction of tumor peptide-specific cytotoxic T cells under serum-free conditions by mature human dendritic cells.
Archives of dermatological research 2000;292(7):325-32.
2000: A H Enk; Jürgen Knop
[Successful management of systemic lupus erythematosus with IgM enriched immunoglobulins].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2000;51(6):416-8.
2000: G P Göllner; G Müller; Ruth Alt; Jürgen Knop; Alexander H Enk
Therapeutic application of T cell receptor mimic peptides or cDNA in the treatment of T cell-mediated skin diseases.
Gene therapy 2000;7(12):1000-4.
2000: Iris Bellinghausen; U Brand; Jürgen Knop; Joachim Saloga
Comparison of allergen-stimulated dendritic cells from atopic and nonatopic donors dissecting their effect on autologous naive and memory T helper cells of such donors.
The Journal of allergy and clinical immunology 2000;105(5):988-96.
2000: Elizabeth R Jarman; K Perschke; Evelyn Montermann; U Herz; H Renz; Jürgen Knop; Angelika B Reske-Kunz
Deficient cytokine response of human allergen-specific T lymphocytes from humanized SCID mice and reconstitution by professional antigen-presenting cells.
The Journal of allergy and clinical immunology 2000;105(5):967-74.
2000: Suzanne M Lohmann; K Galle; Jürgen Knop; A H Enk
CD83+ human dendritic cells transfected with tumor peptide cDNA by electroporation induce specific T-cell responses: A potential tool for gene immunotherapy.
Cancer gene therapy 2000;7(4):605-14.
2000: Julia Steitz; Jürgen Brück; Kerstin Steinbrink; Alexander H Enk; Jürgen Knop; Thomas Tüting
Genetic immunization of mice with human tyrosinase-related protein 2: implications for the immunotherapy of melanoma.
International journal of cancer. Journal international du cancer 2000;86(1):89-94.
2000: Helmut Jonuleit; Thomas Tüting; Julia Steitz; Jürgen Brück; A Giesecke; Kerstin Steinbrink; Jürgen Knop; Alexander H Enk
Efficient transduction of mature CD83+ dendritic cells using recombinant adenovirus suppressed T cell stimulatory capacity.
Gene therapy 2000;7(3):249-54.
2000: G Schwarz; F Laukhuf; Fernando Bittinger; Jürgen Knop; Joachim Saloga
[Calciphylaxis: ischemic tissue necrosis in chronic renal failure. Case report and review of the literature].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2000;51(1):36-40.
2000: Gabriele Müller; A Müller; Helmut Jonuleit; Kerstin Steinbrink; C Szalma; L Paragnik; K Lingnau; E Schmidt; Jürgen Knop; Alexander H Enk
Fetal calf serum-free generation of functionally active murine dendritic cells suitable for in vivo therapeutic approaches.
The Journal of investigative dermatology 2000;114(1):142-9.
1999: Ralf Ross; Xiao-Lan Ross; H Ghadially; T Lahr; J Schwing; Jürgen Knop; Angelika B Reske-Kunz
Mouse langerhans cells differentially express an activated T cell-attracting CC chemokine.
The Journal of investigative dermatology 1999;113(6):991-8.
1999: Thomas Tüting; Julia Steitz; Jürgen Brück; Andrea Gambotto; Kerstin Steinbrink; Albert B DeLeo; P Robbins; Jürgen Knop; Alexander H Enk
Dendritic cell-based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti-melanoma immunity.
The journal of gene medicine 1999;1(6):400-6.
1999: U Brand; Iris Bellinghausen; Alexander H Enk; Helmut Jonuleit; D Becker; Jürgen Knop; Joachim Saloga
Allergen-specific immune deviation from a TH2 to a TH1 response induced by dendritic cells and collagen type I.
The Journal of allergy and clinical immunology 1999;104(5):1052-9.
1999: Joachim Saloga; Jürgen Knop
Superantigens in skin diseases.
European journal of dermatology : EJD 1999;9(7):586-90; quiz 591.
1999: Kerstin Steinbrink; Helmut Jonuleit; G Müller; Gerold Schuler; Jürgen Knop; Alexander H Enk
Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) T cells resulting in a failure to lyse tumor cells.
Blood 1999;93(5):1634-42.
1999: Joachim Saloga; Iris Bellinghausen; Jürgen Knop
Do Tr1 cells play a role in immunotherapy?
International archives of allergy and immunology 1999;118(2-4):210-1.
1999: Melanie Pierkes; Iris Bellinghausen; T Hultsch; G Metz; Jürgen Knop; Joachim Saloga
Decreased release of histamine and sulfidoleukotrienes by human peripheral blood leukocytes after wasp venom immunotherapy is partially due to induction of IL-10 and IFN-gamma production of T cells.
The Journal of allergy and clinical immunology 1999;103(2 Pt 1):326-32.
1999: Iris Bellinghausen; U Brand; Alexander H Enk; Jürgen Knop; Joachim Saloga
Signals involved in the early TH1/TH2 polarization of an immune response depending on the type of antigen.
The Journal of allergy and clinical immunology 1999;103(2 Pt 1):298-306.
1999: U Neisius; Pia Brand; S Plochmann; Joachim Saloga; Jürgen Knop; Detlef Becker
Detection of increased tyrosine phosphorylation in murine Langerhans cells after stimulation with contact sensitizers.
Archives of dermatological research 1999;291(1):22-7.
1999: Alexander H Enk; Jürgen Knop
Mycophenolate is effective in the treatment of pemphigus vulgaris.
Archives of dermatology 1999;135(1):54-6.
1998: S Stoll; Helmut Jonuleit; Edgar Schmitt; Gabriele Müller; H Yamauchi; M Kurimoto; Jürgen Knop; Alexander H Enk
Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development.
European journal of immunology 1998;28(10):3231-9.
1998: T Hultsch; K D Müller; Josef G Meingassner; Maximilian Grassberger; Rudolf E Schopf; Jürgen Knop
Ascomycin macrolactam derivative SDZ ASM 981 inhibits the release of granule-associated mediators and of newly synthesized cytokines in RBL 2H3 mast cells in an immunophilin-dependent manner.
Archives of dermatological research 1998;290(9):501-7.
1998: Alexander H Enk; Jürgen Knop
Treatment of relapsing idiopathic nodular panniculitis (Pfeifer-Weber-Christian disease) with mycophenolate mofetil.
Journal of the American Academy of Dermatology 1998;39(3):508-9.
1998: T Hultsch; Pia Brand; Suzanne M Lohmann; Joachim Saloga; R L Kincaid; Jürgen Knop
Direct evidence that FK506 inhibition of FcepsilonRI-mediated exocytosis from RBL mast cells involves calcineurin.
Archives of dermatological research 1998;290(5):258-63.
1998: U Brand; Iris Bellinghausen; Alexander H Enk; Helmut Jonuleit; D Becker; Jürgen Knop; Joachim Saloga
Influence of extracellular matrix proteins on the development of cultured human dendritic cells.
European journal of immunology 1998;28(5):1673-80.
1998: Joachim Saloga; Alexander H Enk; D Becker; Iris Bellinghausen; S Kühn; Jürgen Knop
Active suppression induced by cutaneous exposure to bacterial superantigen is prevented by interleukin-12 treatment in vivo.
Immunology 1998;93(4):485-92.
1998: UM Kühn; Pia Brand; J Willemsen; Helmut Jonuleit; Alexander H Enk; R van Brandwijk-Petershans; Joachim Saloga; Jürgen Knop; Detlef Becker
Induction of tyrosine phosphorylation in human MHC class II-positive antigen-presenting cells by stimulation with contact sensitizers.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):667-73.
1997: Helmut Jonuleit; UM Kühn; Gabriele Müller; Kerstin Steinbrink; L Paragnik; Edgar Schmitt; Jürgen Knop; Alexander H Enk
Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions.
European journal of immunology 1997;27(12):3135-42.
1997: Kerstin Steinbrink; M Wölfl; Helmut Jonuleit; Jürgen Knop; Alexander H Enk
Induction of tolerance by IL-10-treated dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(10):4772-80.
1997: Alexander H Enk; Helmut Jonuleit; Joachim Saloga; Jürgen Knop
Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma.
International journal of cancer. Journal international du cancer 1997;73(3):309-16.
1997: Thomas Höhler; A Kruger; P M Schneider; Rudolf E Schopf; Jürgen Knop; Christian Rittner; Karl-Hermann Meyer zum Büschenfelde; Elisabeth Märker-Hermann
A TNF-alpha promoter polymorphism is associated with juvenile onset psoriasis and psoriatic arthritis.
The Journal of investigative dermatology 1997;109(4):562-5.
1997: M Mohamadzadeh; Jürgen Knop; S Aliani; P D Cruz
Cytokine expression and antigen-presenting capacity of 4F7+ dendritic cells derived from dermis, spleen, and lymph nodes.
Archives of dermatological research 1997;289(8):435-9.
1997: S Stoll; Gabriele Müller; M Kurimoto; Joachim Saloga; T Tanimoto; H Yamauchi; H Okamura; Jürgen Knop; Alexander H Enk
Production of IL-18 (IFN-gamma-inducing factor) messenger RNA and functional protein by murine keratinocytes.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):298-302.
1997: Iris Bellinghausen; G Metz; Alexander H Enk; S Christmann; Jürgen Knop; Joachim Saloga
Insect venom immunotherapy induces interleukin-10 production and a Th2-to-Th1 shift, and changes surface marker expression in venom-allergic subjects.
European journal of immunology 1997;27(5):1131-9.
1997: Detlef Becker; UM Kühn; U Lempertz; Alexander H Enk; Joachim Saloga; Jürgen Knop
Flow-cytometric screening for the modulation of receptor-mediated endocytosis in human dendritic cells: implications for the development of an in vitro technique for predictive testing of contact sensitizers.
Journal of immunological methods 1997;203(2):171-80.
1997: Helmut Jonuleit; K Wiedemann; Gabriele Müller; J Degwert; U Hoppe; Jürgen Knop; Alexander H Enk
Induction of IL-15 messenger RNA and protein in human blood-derived dendritic cells: a role for IL-15 in attraction of T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(6):2610-5.
1997: Benno Weigmann; J Schwing; H Huber; Ralf Ross; H Mossmann; Jürgen Knop; Angelika B Reske-Kunz
Diminished contact hypersensitivity response in IL-4 deficient mice at a late phase of the elicitation reaction.
Scandinavian journal of immunology 1997;45(3):308-14.
1997: Hans-Christian Schuppe; J Kulig; UM Kühn; U Lempertz; P Kind; Jürgen Knop; Detlef Becker
Immunostimulatory effects of platinum compounds: correlation between sensitizing properties in vivo and modulation of receptor-mediated endocytosis in vitro.
International archives of allergy and immunology 1997;112(2):125-32.
1997: Detlef Becker; J Willemsen; UM Kühn; R van Brandwijk; Jürgen Knop
Increased level of phosphotyrosine in human dendritic cells under stimulation with contact sensitizers but not irritants.
Advances in experimental medicine and biology 1997;417():455-9.
1996: Helmut Jonuleit; Jürgen Knop; Alexander H Enk
Cytokines and their effects on maturation, differentiation and migration of dendritic cells.
Archives of dermatological research 1996;289(1):1-8.
1996: Helmut Jonuleit; S Lohmann; Gabriele Müller; U Lempertz; Alexander H Enk; Jürgen Knop
Specific stabilization of the 4F7 molecule on dendritic cells by contact allergens.
Archives of dermatological research 1996;288(12):745-52.
1996: Thomas Höhler; A Weinmann; Peter M Schneider; Christian Rittner; Rudolf E Schopf; Jürgen Knop; P Hasenclever; K H Meyer zum Büschenfelde; Elisabeth Märker-Hermann
TAP-polymorphisms in juvenile onset psoriasis and psoriatic arthritis.
Human immunology 1996;51(1):49-54.
1996: Iris Bellinghausen; Alexander H Enk; M Mohamadzadeh; S Lohmann; Jürgen Knop; Joachim Saloga
Epidermal cells enhance interleukin 4 and immunoglobulin E production after stimulation with protein allergen.
The Journal of investigative dermatology 1996;107(4):582-8.
1996: Gabriele Müller; Jürgen Knop; Alexander H Enk
Is cytokine expression responsible for differences between allergens and irritants?
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 1996;7(3):177-84.
1996: U Lempertz; UM Kühn; Jürgen Knop; Detlef Becker
An approach to predictive testing of contact sensitizers in vitro by monitoring their influence on endocytotic mechanisms.
International archives of allergy and immunology 1996;111(1):64-70.
1996: Joachim Saloga; E W Gelfand; Jürgen Knop
Superantigens.
Experimental dermatology 1996;5(2):65-71.
1995: Gabriele Müller; Joachim Saloga; T Germann; G Schuler; Jürgen Knop; Alexander H Enk
IL-12 as mediator and adjuvant for the induction of contact sensitivity in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):4661-8.
1995: M Mohamadzadeh; A Takashima; I Dougherty; Jürgen Knop; P R Bergstresser; Ponciano D Cruz
Ultraviolet B radiation up-regulates the expression of IL-15 in human skin.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(9):4492-6.
1995: Joachim Saloga; Alexander H Enk; Detlef Becker; S Spieles; Iris Bellinghausen; Jürgen Knop
Prevention and reversal of superantigen-induced anergy by contact allergen exposure.
Experimental dermatology 1995;4(5):308-12.
1995: G Erdmann; Joachim Saloga; M Mohamadzadeh; Detlef Becker; Jürgen Knop; Alexander H Enk
Heat-stable antigen is expressed by murine keratinocytes and delivers costimulatory signals in T-cell activation.
Experimental dermatology 1995;4(5):291-6.
1995: H Huber; P Descossy; R van Brandwijk; Jürgen Knop
Activation of murine epidermal TCR-gamma delta+ T cells by keratinocytes treated with contact sensitizers.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(6):2888-94.
1995: Detlef Becker; U Lempertz; Alexander H Enk; Joachim Saloga; Jürgen Knop
Contact sensitizers modulate mechanisms of receptor-mediated endocytosis but not fluid-phase endocytosis in murine epidermal Langerhans cells.
Experimental dermatology 1995;4(4 Pt 1):211-7.
1995: Joachim Saloga; Alexander H Enk; Detlef Becker; M Mohamadzadeh; S Spieles; Iris Bellinghausen; D Y Leung; E W Gelfand; Jürgen Knop
Modulation of contact sensitivity responses by bacterial superantigen.
The Journal of investigative dermatology 1995;105(2):220-4.
1995: H Huber; P Descossy; E Regier; R van Brandwijk; Jürgen Knop
Activation of phenotypically heterogeneous murine T cell receptor gamma delta + dendritic epidermal T cells by self-antigen(s).
International archives of allergy and immunology 1995;107(4):498-507.
1995: Jürgen Knop; Alexander H Enk
Cellular and molecular mechanisms in the induction phase of contact sensitivity.
International archives of allergy and immunology 1995;107(1-3):231-2.
1995: UM Kühn; U Lempertz; Jürgen Knop; Detlef Becker
A new method for phenotyping proliferating cell nuclear antigen positive cells using flow cytometry: implications for analysis of the immune response in vivo.
Journal of immunological methods 1995;179(2):215-22.
1995: G Müller; Joachim Saloga; T Germann; Iris Bellinghausen; M Mohamadzadeh; Jürgen Knop; Alexander H Enk
Human keratinocyte-derived IL-12 affects LC-induced allogeneic T-cell responses.
Advances in experimental medicine and biology 1995;378():519-21.
1995: A Pavlidou; Jürgen Knop; M Mohamadzadeh; E Rüde; G Gradehandt
Processing and presentation of protein and parasite-derived antigens by 4F7+ dendritic cells.
Advances in experimental medicine and biology 1995;378():233-5.
1995: M Mohamadzadeh; Jürgen Knop; Gerhard Kolde
In vitro analysis of the phenotypical and functional properties of the 4F7+ cutaneous accessory dendritic cell.
Archives of dermatological research 1995;287(3-4):273-8.
1994: M Mohamadzadeh; A Pavlidou; Alexander H Enk; Jürgen Knop; E Rüde; G Gradehandt
Freshly isolated mouse 4F7+ splenic dendritic cells process and present exogenous antigens to T cells.
European journal of immunology 1994;24(12):3170-4.
1994: M Mohamadzadeh; M Müller; T Hultsch; Alexander H Enk; Joachim Saloga; Jürgen Knop
Enhanced expression of IL-8 in normal human keratinocytes and human keratinocyte cell line HaCaT in vitro after stimulation with contact sensitizers, tolerogens and irritants.
Experimental dermatology 1994;3(6):298-303.
1994: G Müller; Joachim Saloga; T Germann; Iris Bellinghausen; M Mohamadzadeh; Jürgen Knop; Alexander H Enk
Identification and induction of human keratinocyte-derived IL-12.
The Journal of clinical investigation 1994;94(5):1799-805.
1994: Alexander H Enk; Joachim Saloga; Detlef Becker; M Mohamadzadeh; Jürgen Knop
Induction of hapten-specific tolerance by interleukin 10 in vivo.
The Journal of experimental medicine 1994;179(4):1397-402.
1994: Detlef Becker; Gerhard Kolde; K Reske; Jürgen Knop
An in vitro test for endocytotic activation of murine epidermal Langerhans cells under the influence of contact allergens.
Journal of immunological methods 1994;169(2):195-204.
1993: M Mohamadzadeh; T Lipkow; Gerhard Kolde; Jürgen Knop
Expression of an epitope as detected by the novel monoclonal antibody 4F7 on dermal and epidermal dendritic cells. I. Identification and characterization of the 4F7+ dendritic cell in situ.
The Journal of investigative dermatology 1993;101(6):832-8.
1993: M Mohamadzadeh; Helmut Jonuleit; Gerhard Kolde; A Pavlidou; Edgar Schmitt; Jürgen Knop
Functional and morphological characterization of 4F7+ spleen accessory dendritic cells.
International immunology 1993;5(6):615-24.
1993: Detlef Becker; Jürgen Knop
Mechanism in allergic contact dermatitis.
Experimental dermatology 1993;2(2):63-9.
1993: U Neiss; Detlef Becker; Jürgen Knop; K Reske
Modulation of MHC class II determinants on rat Langerhans cells during short term culture.
Advances in experimental medicine and biology 1993;329():29-34.
1992: Gerhard Kolde; M Mohamadzadeh; T Lipkow; Jürgen Knop
A novel monoclonal antibody to a distinct subset of cutaneous dendritic cells.
The Journal of investigative dermatology 1992;99(5):56S-58S.
1992: Detlef Becker; M Mohamadzadeh; K Reske; Jürgen Knop
Increased level of intracellular MHC class II molecules in murine Langerhans cells following in vivo and in vitro administration of contact allergens.
The Journal of investigative dermatology 1992;99(5):545-9.
1992: O Wildner; T Lipkow; Jürgen Knop
Increased expression of ICAM-1, E-selectin, and VCAM-1 by cultured human endothelial cells upon exposure to haptens.
Experimental dermatology 1992;1(4):191-8.
1992: J Haas; T Lipkow; M Mohamadzadeh; Gerhard Kolde; Jürgen Knop
Induction of inflammatory cytokines in murine keratinocytes upon in vivo stimulation with contact sensitizers and tolerizing analogues.
Experimental dermatology 1992;1(2):76-83.
1992: Detlef Becker; U Neiss; S Neis; K Reske; Jürgen Knop
Contact allergens modulate the expression of MHC class II molecules on murine epidermal Langerhans cells by endocytotic mechanisms.
The Journal of investigative dermatology 1992;98(5):700-5.
1992: Gerhard Kolde; K Schulze-Osthoff; H Meyer; Jürgen Knop
Immunohistological and immunoelectron microscopic identification of TNF alpha in normal human and murine epidermis.
Archives of dermatological research 1992;284(3):154-8.
1991: Detlef Becker; Angelika B Reske-Kunz; Jürgen Knop; K Reske
Biochemical properties of MHC class II molecules endogenously synthesized and expressed by mouse Langerhans cells.
European journal of immunology 1991;21(5):1213-20.
1990: Jürgen Knop
Immunologic effects of interferon.
The Journal of investigative dermatology 1990;95(6 Suppl):72S-74S.
1989: A Schöne; E Zimmermann; Jürgen Knop
Induction of procoagulant activity in human epidermal cells.
Archives of dermatological research 1989;281(5):316-20.
1989: Jürgen Knop
Diagnostic procedures in immunodeficiency. The arsenal, its limits and pitfalls.
Current problems in dermatology 1989;18():50-9.
1988: Gerhard Kolde; Jürgen Knop
Ultrastructural localization of 2,4-dinitrophenyl groups in mouse epidermis following skin painting with 2,4-dinitrofluorobenzene and 2,4-dinitrothiocyanatebenzene: an immunoelectron microscopical study.
The Journal of investigative dermatology 1988;90(3):320-4.
1988: U Malorny; Jürgen Knop; G Burmeister; Clemens Sorg
Immunohistochemical demonstration of migration inhibitory factor (MIF) in experimental allergic contact dermatitis.
Clinical and experimental immunology 1988;71(1):164-70.
1988: J Saloga; Jürgen Knop; Gerhard Kolde
Ultrastructural cytochemical visualization of chromium in the skin of sensitized guinea pigs.
Archives of dermatological research 1988;280(4):214-9.