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Sakari Knuutila

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Katja Tuononen; Aino Wirtanen; Jenny M Andrews; Pekka Ellonen; Sari Hannula; Aija Knuuttila; Sonja Lagström; Satu Mäki-Nevala; Mikko Rönty; Kaisa Salmenkivi; Virinder Kaur Sarhadi; Aino I Telaranta-Keerie; Sakari Knuutila
Comparison of targeted next-generation sequencing (NGS) and real-time PCR in the detection of EGFR, KRAS, and BRAF mutations on formalin-fixed, paraffin-embedded tumor material of non-small cell lung carcinoma-superiority of NGS.
Neda Mosakhani; Laura Pazzaglia; Piero Picci; Irene Quattrini; Maria Serena Benassi; Ioana Borze; Sakari Knuutila
MicroRNA expression profiles in metastatic and non-metastatic giant cell tumor of bone.
Kowan Ja Jee; Sakari Knuutila; Katri Aro; Kristiina Heikinheimo; Antti Mäkitie; Edward W Odell; Fabricio Passador-Santos; Marta Persson; Göran Stenman; Kaarina Sundelin; Ilmo Leivo
Genomic profiles and CRTC1-MAML2 fusion distinguish different subtypes of mucoepidermoid carcinoma.

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2013: Katja Tuononen; Aino Wirtanen; Jenny M Andrews; Pekka Ellonen; Sari Hannula; Aija Knuuttila; Sonja Lagström; Satu Mäki-Nevala; Mikko Rönty; Kaisa Salmenkivi; Virinder Kaur Sarhadi; Aino I Telaranta-Keerie; Sakari Knuutila
Comparison of targeted next-generation sequencing (NGS) and real-time PCR in the detection of EGFR, KRAS, and BRAF mutations on formalin-fixed, paraffin-embedded tumor material of non-small cell lung carcinoma-superiority of NGS.
Genes, chromosomes & cancer 2013;52(5):503-11.
2013: Neda Mosakhani; Laura Pazzaglia; Piero Picci; Irene Quattrini; Maria Serena Benassi; Ioana Borze; Sakari Knuutila
MicroRNA expression profiles in metastatic and non-metastatic giant cell tumor of bone.
Histology and histopathology 2013;28(5):671-8.
2013: Kowan Ja Jee; Sakari Knuutila; Katri Aro; Kristiina Heikinheimo; Antti Mäkitie; Edward W Odell; Fabricio Passador-Santos; Marta Persson; Göran Stenman; Kaarina Sundelin; Ilmo Leivo
Genomic profiles and CRTC1-MAML2 fusion distinguish different subtypes of mucoepidermoid carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013;26(2):213-22.
2013: Katja Tuononen; Aino Wirtanen; Stuart Bloor; Pekka Ellonen; Aija Knuuttila; Satu Remes; Mikko Rönty; Kaisa Salmenkivi; Virinder Kaur Sarhadi; Aino I Telaranta-Keerie; Sakari Knuutila
Targeted resequencing reveals ALK fusions in non-small cell lung carcinomas detected by FISH, immunohistochemistry, and real-time RT-PCR: a comparison of four methods.
BioMed research international 2013;2013():757490.
2012: Neda Mosakhani; Ulla M Saarinen-Pihkala; Virinder Kaur Sarhadi; Katja Tuononen; Anu Usvasalo; Marja-Liisa Karjalainen-Lindsberg; Leo Lahti; Sakari Knuutila
MicroRNA profiling in pediatric acute lymphoblastic leukemia: novel prognostic tools.
Leukemia & lymphoma 2012;53(12):2517-20.
2012: Tarja Niini; Karolin H Nord; Suvi Savola; Ilari Scheinin; Tom Böhling; Jaakko Hollmén; Aarne Kivioja; Leo Lahti; Fredrik Mertens; Sakari Knuutila
Homozygous deletions of cadherin genes in chondrosarcoma-an array comparative genomic hybridization study.
Cancer genetics 2012;205(11):588-93.
2012: Neda Mosakhani; Pia Osterlund; Raija Ristamäki; Ioana Borze; Marja-Liisa Karjalainen-Lindsberg; Sakari Knuutila; Leo Lahti; Jari Sundström; Virinder Kaur Sarhadi
MicroRNA profiling predicts survival in anti-EGFR treated chemorefractory metastatic colorectal cancer patients with wild-type KRAS and BRAF.
Cancer genetics 2012;205(11):545-51.
2012: Wael M Abdel-Rahman; Sakari Knuutila; Salla Ruosaari; Päivi Peltomäki
Differential roles of EPS8 in carcinogenesis: loss of protein expression in a subset of colorectal carcinoma and adenoma.
World journal of gastroenterology : WJG 2012;18(29):3896-903.
2012: Sakari Knuutila; Satu Mustjoki
Morphology antibody chromosome technique for determining phenotype and genetic status of the same cell.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2012;Chapter 4():Unit4.7.
2012: Hanna Pelttari; Camilla Schalin-Jäntti; Johanna Arola; Sakari Knuutila; Eliisa Löyttyniemi; Matti J Välimäki
BRAF V600E mutation does not predict recurrence after long-term follow-up in TNM stage I or II papillary thyroid carcinoma patients.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2012;120(5):380-6.
2012: Fumihiko Nakatani; Massimo Negrini; Piero Picci; Karl-Ludwig Schaefer; Massimo Serra; Selena Ventura; Marco Alberghini; Valentina Del Monaco; Manuela Ferracin; Stefano Ferrari; Andrea Grilli; Sakari Knuutila; Maria Cristina Manara; Gianfranco Mattia; Katia Scotlandi
miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy.
The Journal of pathology 2012;226(5):796-805.
2012: Franz X Gruber; Tobias Gedde-Dahl; Rasmus Goll; Sakari Knuutila; Tuija Lundán; Ingvild Mikkola; Kimmo Porkka; Ole Petter Rekvig; Kari Remes; Aleksandra Silye; Henrik Hjorth-Hansen
BCR-ABL isoforms associated with intrinsic or acquired resistance to imatinib: more heterogeneous than just ABL kinase domain point mutations?
Medical oncology (Northwood, London, England) 2012;29(1):219-26.
2012: José Caldas; Ali Faisal; Nils Gehlenborg; Eeva Kettunen; Sakari Knuutila; Andrew G Nicholson; Mikko Rönty; Alvis Brazma; Samuel Kaski
Data-driven information retrieval in heterogeneous collections of transcriptomics data links SIM2s to malignant pleural mesothelioma.
Bioinformatics (Oxford, England) 2012;28(2):246-53.
2012: Matteo Brunelli; Francesco Calabrò; Anna Caliò; Ioana Borze; Emilio Bria; Sara Cingarlini; Albino Eccher; Eliana Gilioli; Stefano Gobbo; Antonio Iannucci; Sakari Knuutila; Guido Martignoni; Francesco Massari; Alessia Nottegar; Claudia Parolini; Serena Pedron; Antonio Santo; Francesca Simionato; Luca Tondulli; Giampaolo Tortora; Marco Chilosi
True 3q chromosomal amplification in squamous cell lung carcinoma by FISH and aCGH molecular analysis: impact on targeted drugs.
PloS one 2012;7(12):e49689.
2012: S Ninomiya; Riitta Räty; Ulla M Saarinen-Pihkala; Anne Tyybäkinoja; A Usvasalo; I Borze; Erkki Elonen; Sakari Knuutila
Integrated analysis of gene copy number, copy neutral LOH, and microRNA profiles in adult acute lymphoblastic leukemia.
Cytogenetic and genome research 2012;136(4):246-55.
2012: Neda Mosakhani; Tarja Niini; Suvi Savola; Katia Scotlandi; Gayle Leen; Antonio Llombart Bosch; José Antonio López-Guerrero; Isidro Machado; Silvia Calabuig-Fariñas; Mohamed Guled; Sakari Knuutila
An integrated analysis of miRNA and gene copy numbers in xenografts of Ewing's sarcoma.
Journal of experimental & clinical cancer research : CR 2012;31():24.
2012: Katja Tuononen; Olli Tynninen; Anne Tyybäkinoja; Miia Antikainen; Ari Hirvonen; Mikael Lindlöf; Hanna Mäenpää; Juha Näpänkangas; Anders Paetau; Virinder Kaur Sarhadi; Sakari Knuutila
The hypermethylation of the O6-methylguanine-DNA methyltransferase gene promoter in gliomas--correlation with array comparative genome hybridization results and IDH1 mutation.
Genes, chromosomes & cancer 2012;51(1):20-9.
2012: Neda Mosakhani; Pia Osterlund; Raija Ristamäki; Virinder Kaur Sarhadi; Jari Sundström; Ioana Borze; Marja-Liisa Karjalainen-Lindsberg; Sakari Knuutila
MicroRNA profiling differentiates colorectal cancer according to KRAS status.
Genes, chromosomes & cancer 2012;51(1):1-9.
2011: Penny Nymark; Kaisa Salmenkivi; Leo Lahti; Sisko Anttila; Ioana Borze; Ali Faisal; Mohamed Guled; Eeva Kettunen; Sakari Knuutila
Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer.
Genes, chromosomes & cancer 2011;50(8):585-97.
2011: Linda Siggberg; Aki Mustonen; Robert Schuit; Gajja S Salomons; Birthe Roos; K Michael Gibson; Cornelis Jakobs; Jaakko Ignatius; Sakari Knuutila
Familial 6p22.2 duplication associates with mild developmental delay and increased SSADH activity.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(4):448-53.
2011: Tarja Niini; Leo Lahti; Francesca Michelacci; Shinsuke Ninomiya; Claudia M Hattinger; Mohamed Guled; Tom Böhling; Piero Picci; Massimo Serra; Sakari Knuutila
Array comparative genomic hybridization reveals frequent alterations of G1/S checkpoint genes in undifferentiated pleomorphic sarcoma of bone.
Genes, chromosomes & cancer 2011;50(5):291-306.
2011: Kristiina Avela; Katja Aktan-Collan; Nina Horelli-Kuitunen; Sakari Knuutila; Mirja Somer
A microduplication on chromosome 17p13.1p13.3 including the PAFAH1B1 (LIS1) gene.
American journal of medical genetics. Part A 2011;155A(4):875-9.
2011: Ioana Borze; Mohamed Guled; Suad Musse; Anna Raunio; Erkki Elonen; Ulla M Saarinen-Pihkala; Marja-Liisa Karjalainen-Lindsberg; Leo Lahti; Sakari Knuutila
MicroRNA microarrays on archive bone marrow core biopsies of leukemias--method validation.
Leukemia research 2011;35(2):188-95.
2011: Suvi Savola; Katia Scotlandi; Arto Klami; Sakari Knuutila; Cristina Manara; Samuel Myllykangas; Piero Picci; Jukka Vakkila
High Expression of Complement Component 5 (C5) at Tumor Site Associates with Superior Survival in Ewing's Sarcoma Family of Tumour Patients.
ISRN oncology 2011;2011():168712.
2011: L Siggberg; P Olsén; K Näntö-Salonen; Sakari Knuutila
19p13.3 aberrations are associated with dysmorphic features and deviant psychomotor development.
Cytogenetic and genome research 2011;132(1-2):8-15.
2010: Neda Mosakhani; Mohamed Guled; Leo Lahti; Ioana Borze; Minna Forsman; Virve Pääkkönen; Jorma Ryhänen; Sakari Knuutila
Unique microRNA profile in Dupuytren's contracture supports deregulation of β-catenin pathway.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(11):1544-52.
2010: Anu Usvasalo; Erkki Elonen; Ulla M Saarinen-Pihkala; Riikka Räty; Arja Harila-Saari; Pirjo Koistinen; Eeva-Riitta Savolainen; Sakari Knuutila; Jaakko Hollmén
Prognostic classification of patients with acute lymphoblastic leukemia by using gene copy number profiles identified from array-based comparative genomic hybridization data.
Leukemia research 2010;34(11):1476-82.
2010: Linda Siggberg; Sirpa Ala-Mello; Elisa Jaakkola; Esa Kuusinen; Robert Schuit; Juergen Kohlhase; Detlef Böhm; Jaakko Ignatius; Sakari Knuutila
Array CGH in molecular diagnosis of mental retardation - A study of 150 Finnish patients.
American journal of medical genetics. Part A 2010;152A(6):1398-410.
2010: Gemma Armengol; Sakari Knuutila; Juan-José Lozano; Irene Madrigal; Maria Rosa Caballín
Identification of human specific gene duplications relative to other primates by array CGH and quantitative PCR.
Genomics 2010;95(4):203-9.
2010: Anu Usvasalo; Shinsuke Ninomiya; Riikka Räty; Jaakko Hollmén; Ulla M Saarinen-Pihkala; Erkki Elonen; Sakari Knuutila
Focal 9p instability in hematologic neoplasias revealed by comparative genomic hybridization and single-nucleotide polymorphism microarray analyses.
Genes, chromosomes & cancer 2010;49(4):309-18.
2010: Ioana Borze; Eeva Juvonen; Shinsuke Ninomiya; Kowan Ja Jee; Erkki Elonen; Sakari Knuutila
High-resolution oligonucleotide array comparative genomic hybridization study and methylation status of the RPS14 gene in de novo myelodysplastic syndromes.
Cancer genetics and cytogenetics 2010;197(2):166-73.
2010: Tarja Niini; José Antonio López-Guerrero; Shinsuke Ninomiya; Mohamed Guled; Claudia M Hattinger; Francesca Michelacci; Tom Böhling; Antonio Llombart Bosch; Piero Picci; Massimo Serra; Sakari Knuutila
Frequent deletion of CDKN2A and recurrent coamplification of KIT, PDGFRA, and KDR in fibrosarcoma of bone--an array comparative genomic hybridization study.
Genes, chromosomes & cancer 2010;49(2):132-43.
2010: Ilari Scheinin; José A Ferreira; Sakari Knuutila; Gerrit A Meijer; Mark A van de Wiel; Bauke Ylstra
CGHpower: exploring sample size calculations for chromosomal copy number experiments.
BMC bioinformatics 2010;11():331.
2010: Gemma Armengol; Anna Canellas; Yolanda Alvarez; Pilar Bastida; José Sánchez De Toledo; Maria Del Mar Pérez-Iribarne; Mireia Camós; Esperanza Tuset; Jesús Estella; María Dolores Coll; Maria Rosa Caballín; Sakari Knuutila
Genetic changes including gene copy number alterations and their relation to prognosis in childhood acute myeloid leukemia.
Leukemia & lymphoma 2010;51(1):114-24.
2009: Anu Usvasalo; Riikka Räty; Arja Harila-Saari; Pirjo Koistinen; Eeva-Riitta Savolainen; Kim Vettenranta; Sakari Knuutila; Erkki Elonen; Ulla M Saarinen-Pihkala
Acute lymphoblastic leukemias with normal karyotypes are not without genomic aberrations.
Cancer genetics and cytogenetics 2009;192(1):10-7.
2009: H Peterson; Hannele Laivuori; Erja Kerkelä; H Jiao; Liisa Hiltunen; S Heino; Inkeri Tiala; Sakari Knuutila; Vesa Rasi; Juha Kere; Katja Kivinen
ROCK2 allelic variants are not associated with pre-eclampsia susceptibility in the Finnish population.
Molecular human reproduction 2009;15(7):443-9.
2009: Mohamed Guled; Leo Lahti; Pamela M Lindholm; Kaisa Salmenkivi; Izhar Bagwan; Andrew G Nicholson; Sakari Knuutila
CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant mesothelioma -A miRNA microarray analysis.
Genes, chromosomes & cancer 2009;48(7):615-23.
2009: Taru A Koski; Heli J Lehtonen; Kowan J Jee; Shinsuke Ninomiya; Simon A Joosse; Pia Vahteristo; Maija Kiuru; Auli Karhu; Heli Sammalkorpi; Sakari Vanharanta; Rainer Lehtonen; Henrik Edgren; petra nederlof; Marja Hietala; Kristiina Aittomäki; Riitta Herva; Sakari Knuutila; Lauri A Aaltonen; Virpi Launonen
Array comparative genomic hybridization identifies a distinct DNA copy number profile in renal cell cancer associated with hereditary leiomyomatosis and renal cell cancer.
Genes, chromosomes & cancer 2009;48(7):544-51.
2009: Katia Scotlandi; Daniel Remondini; Gastone Castellani; Maria Cristina Manara; Filippo Nardi; Lara Cantiani; Mirko Francesconi; Mario Mercuri; Anna Maria Caccuri; Massimo Serra; Sakari Knuutila; Piero Picci
Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(13):2209-16.
2009: Karolin H Hallor; Johan Staaf; Judith Bovee; Pancras Hogendoorn; Anne-Marie Cleton-Jansen; Sakari Knuutila; Suvi Savola; Tarja Niini; Otte Brosjö; Henrik C F Bauer; Fredrik Vult von Steyern; Kjell Jonsson; Mikael Skorpil; Nils Mandahl; Fredrik Mertens
Genomic profiling of chondrosarcoma: chromosomal patterns in central and peripheral tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(8):2685-94.
2009: P M Lindholm; Ylermi Soini; M Myllärniemi; Sakari Knuutila; M Heikinheimo; Vuokko L Kinnula; K Salmenkivi
Expression of GATA-6 transcription factor in pleural malignant mesothelioma and metastatic pulmonary adenocarcinoma.
Journal of clinical pathology 2009;62(4):339-44.
2009: Musaffe Tuna; Sakari Knuutila; Gordon B Mills
Uniparental disomy in cancer.
Trends in molecular medicine 2009;15(3):120-8.
2009: Penny Nymark; Eeva Kettunen; Mervi Aavikko; Salla Ruosaari; Eeva Kuosma; Esa Vanhala; Kaisa Salmenkivi; Risto Pirinen; Antti Karjalainen; Sakari Knuutila; Harriet Wikman; Sisko Anttila
Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(2):468-75.
2009: Suvi Savola; Arto Klami; Abhishek Tripathi; Tarja Niini; Massimo Serra; Piero Picci; Samuel Kaski; Diana Zambelli; Katia Scotlandi; Sakari Knuutila
Combined use of expression and CGH arrays pinpoints novel candidate genes in Ewing sarcoma family of tumors.
BMC cancer 2009;9():17.
2009: Satu Mustjoki; Ioana Borze; Terra L Lasho; Riitta Alitalo; Animesh Pardanani; Sakari Knuutila; Eeva Juvonen
JAK2V617F mutation and spontaneous megakaryocytic or erythroid colony formation in patients with essential thrombocythaemia (ET) or polycythaemia vera (PV).
Leukemia research 2009;33(1):54-9.
2008: Marcelo L Larramendy; Massimiliano Gentile; Sonia Soloneski; Sakari Knuutila; Tom Böhling
Does comparative genomic hybridization reveal distinct differences in DNA copy number sequence patterns between leiomyosarcoma and malignant fibrous histiocytoma?
Cancer genetics and cytogenetics 2008;187(1):1-11.
2008: Sirpa Ala-Mello; Linda Siggberg; Sakari Knuutila; Harriet von Koskull; Mervi Taskinen; Maarit Peippo
Further evidence for a relationship between the 5p15 chromosome region and the oculoauriculovertebral anomaly.
American journal of medical genetics. Part A 2008;146A(19):2490-4.
2008: Samuel Myllykangas; Siina Junnila; Arto Kokkola; Reija Autio; Ilari Scheinin; Tuula Kiviluoto; Marja-Liisa Karjalainen-Lindsberg; Jaakko Hollmén; Sakari Knuutila; Pauli Puolakkainen; Outi Monni
Integrated gene copy number and expression microarray analysis of gastric cancer highlights potential target genes.
International journal of cancer. Journal international du cancer 2008;123(4):817-25.
2008: Anu Usvasalo; Riikka Räty; Sakari Knuutila; Kim Vettenranta; Arja Harila-Saari; Esa Jantunen; Marjut Kauppila; Pirjo Koistinen; Katriina Parto; Pekka Riikonen; Toivo T Salmi; Raija Silvennoinen; Erkki Elonen; Ulla M Saarinen-Pihkala
Acute lymphoblastic leukemia in adolescents and young adults in Finland.
Haematologica 2008;93(8):1161-8.
2008: Anu Usvasalo; Suvi Savola; Riikka Räty; Kim Vettenranta; Arja Harila-Saari; Pirjo Koistinen; Eeva-Riitta Savolainen; Erkki Elonen; Ulla M Saarinen-Pihkala; Sakari Knuutila
CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults: an array CGH study.
Leukemia research 2008;32(8):1228-35.
2008: Ioana Borze; Satu Mustjoki; Satu Mustjokio; Eeva Juvonen; Sakari Knuutila
Oligoarray comparative genomic hybridization in polycythemia vera and essential thrombocythemia.
Haematologica 2008;93(7):1098-100.
2008: Emmi I Joensuu; Wael M Abdel-Rahman; Miina Ollikainen; Salla Ruosaari; Sakari Knuutila; Päivi Peltomäki
Epigenetic signatures of familial cancer are characteristic of tumor type and family category.
Cancer research 2008;68(12):4597-605.
2008: Mohamed Guled; Samuel Myllykangas; Henry F Frierson; Stacey E Mills; Sakari Knuutila; Edward B Stelow
Array comparative genomic hybridization analysis of olfactory neuroblastoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21(6):770-8.
2008: Sippy Kaur; Minna Forsman; Jorma Ryhänen; Sakari Knuutila; Marcelo L Larramendy
No gene copy number changes in Dupuytren's contracture by array comparative genomic hybridization.
Cancer genetics and cytogenetics 2008;183(1):6-8.
2008: Salla T Ruosaari; Penny E H Nymark; Mervi M Aavikko; Eeva Kettunen; Sakari Knuutila; Jaakko Hollmén; Hannu Norppa; Sisko Anttila
Aberrations of chromosome 19 in asbestos-associated lung cancer and in asbestos-induced micronuclei of bronchial epithelial cells in vitro.
Carcinogenesis 2008;29(5):913-7.
2008: Anne Tyybäkinoja; Erkki Elonen; Hanna Vauhkonen; Janna Saarela; Sakari Knuutila
Single nucleotide polymorphism microarray analysis of karyotypically normal acute myeloid leukemia reveals frequent copy number neutral loss of heterozygosity.
Haematologica 2008;93(4):631-2.
2008: Tuija Lundán; Vesa Juvonen; Martin C Mueller; Satu Mustjoki; Taina Lakkala; Veli Kairisto; Andreas Hochhaus; Sakari Knuutila; Kimmo Porkka
Comparison of bone marrow high mitotic index metaphase fluorescence in situ hybridization to peripheral blood and bone marrow real time quantitative polymerase chain reaction on the International Scale for detecting residual disease in chronic myeloid leukemia.
Haematologica 2008;93(2):178-85.
2008: Wael M Abdel-Rahman; Sakari Knuutila; Päivi Peltomäki; David J Harrison; Scott A Bader
Truncation of MBD4 predisposes to reciprocal chromosomal translocations and alters the response to therapeutic agents in colon cancer cells.
DNA repair 2008;7(2):321-8.
2008: Salla Ruosaari; Tuija Hienonen-Kempas; Anne Puustinen; Virinder K Sarhadi; Jaakko Hollmén; Sakari Knuutila; Juha Saharinen; Harriet Wikman; Sisko Anttila
Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients.
BMC medical genomics 2008;1():55.
2008: David Lindgren; Sigurdur Gudjonsson; Kowan Ja Jee; Fredrik Liedberg; Sonja Aits; Anna Andersson; Gunilla Chebil; Ake Borg; Sakari Knuutila; Thoas Fioretos; Wiking Månsson; Mattias Höglund
Recurrent and multiple bladder tumors show conserved expression profiles.
BMC cancer 2008;8():183.
2008: Samuel Myllykangas; Jarkko Tikka; Tom Böhling; Sakari Knuutila; Jaakko Hollmén
Classification of human cancers based on DNA copy number amplification modeling.
BMC medical genomics 2008;1():15.
2008: Ilari Scheinin; Samuel Myllykangas; Ioana Borze; Tom Böhling; Sakari Knuutila; Juha Saharinen
CanGEM: mining gene copy number changes in cancer.
Nucleic acids research 2008;36(Database issue):D830-5.
2007: Balint Nagy; Sara Galimberti; Edoardo Benedetti; francesco caracciolo; Simone Pacini; Juhani Vilpo; Anna Ferrer; Erkki Elonen; Kaarle Franssila; Sakari Knuutila; Mario Petrini
RAF-1 over-expression does condition survival of patients affected by aggressive mantle cell lymphoma.
Leukemia research 2007;31(11):1595-7.
2007: Hanna Vauhkonen; Tom Böhling; Saad Eissa; Sohair Shoman; Sakari Knuutila
Can bladder adenocarcinomas be distinguished from schistosomiasis-associated bladder cancers by using array comparative genomic hybridization analysis?
Cancer genetics and cytogenetics 2007;177(2):153-7.
2007: Sílvia Casas; Ramon Gomis; Fiona M Gribble; Jordi Altirriba; Sakari Knuutila; Anna Novials
Impairment of the ubiquitin-proteasome pathway is a downstream endoplasmic reticulum stress response induced by extracellular human islet amyloid polypeptide and contributes to pancreatic beta-cell apoptosis.
Diabetes 2007;56(9):2284-94.
2007: Gemma Armengol; Saad Eissa; Juan Jose Lozano ; Sohair Shoman; Lauro Sumoy; Maria Rosa Caballín; Sakari Knuutila
Genomic imbalances in Schistosoma-associated and non-Schistosoma-associated bladder carcinoma. An array comparative genomic hybridization analysis.
Cancer genetics and cytogenetics 2007;177(1):16-9.
2007: Harriet Wikman; Salla Ruosaari; Penny Nymark; Virinder K Sarhadi; J Saharinen; Esa Vanhala; Antti Karjalainen; Jaakko Hollmén; Sakari Knuutila; Sisko Anttila
Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.
Oncogene 2007;26(32):4730-7.
2007: Kristiina Heikinheimo; Kowan Ja Jee; Peter R Morgan; Balint Nagy; Sakari Knuutila; Ilmo Leivo
Genetic changes in sporadic keratocystic odontogenic tumors (odontogenic keratocysts).
Journal of dental research 2007;86(6):544-9.
2007: Reetta Assämäki; Maarit Sarlomo-Rikala; José Antonio Lopez-Guerrero; Jerzy Lasota; Leif C Andersson; Antonio Llombart Bosch; Markku Miettinen; Sakari Knuutila
Array comparative genomic hybridization analysis of chromosomal imbalances and their target genes in gastrointestinal stromal tumors.
Genes, chromosomes & cancer 2007;46(6):564-76.
2007: Claudia Haferlach; Harald Rieder; Debra M Lillington; Nicole Dastugue; Anne Hagemeijer; Jochen Harbott; Stephan Stilgenbauer; Sakari Knuutila; Bertil Johansson; Christa Fonatsch
Proposals for standardized protocols for cytogenetic analyses of acute leukemias, chronic lymphocytic leukemia, chronic myeloid leukemia, chronic myeloproliferative disorders, and myelodysplastic syndromes.
Genes, chromosomes & cancer 2007;46(5):494-9.
2007: Katja Kivinen; Hanna Peterson; Liisa Hiltunen; Hannele Laivuori; Sanna Heino; Inkeri Tiala; Sakari Knuutila; Vesa Rasi; Juha Kere
Evaluation of STOX1 as a preeclampsia candidate gene in a population-wide sample.
European journal of human genetics : EJHG 2007;15(4):494-7.
2007: Anne Tyybäkinoja; Erkki Elonen; K Piippo; K Porkka; Sakari Knuutila
Oligonucleotide array-CGH reveals cryptic gene copy number alterations in karyotypically normal acute myeloid leukemia.
Leukemia 2007;21(3):571-4.
2007: Samuel Myllykangas; Tom Böhling; Sakari Knuutila
Specificity, selection and significance of gene amplifications in cancer.
Seminars in cancer biology 2007;17(1):42-55.
2007: P M Lindholm; Kaisa Salmenkivi; Hanna Vauhkonen; A G Nicholson; Sisko Anttila; V L Kinnula; Sakari Knuutila
Gene copy number analysis in malignant pleural mesothelioma using oligonucleotide array CGH.
Cytogenetic and genome research 2007;119(1-2):46-52.
2007: Hanna Vauhkonen; Matti Vauhkonen; Pentti Sipponen; Sakari Knuutila
Oligonucleotide array comparative genomic hybridization refines the structure of 8p23.1, 17q12 and 20q13.2 amplifications in gastric carcinomas.
Cytogenetic and genome research 2007;119(1-2):39-45.
2007: Suvi Savola; F Nardi; K Scotlandi; Piero Picci; Sakari Knuutila
Microdeletions in 9p21.3 induce false negative results in CDKN2A FISH analysis of Ewing sarcoma.
Cytogenetic and genome research 2007;119(1-2):21-6.
2007: Hanna Vauhkonen; S Heino; Samuel Myllykangas; P M Lindholm; Suvi Savola; Sakari Knuutila
Etiology of specific molecular alterations in human malignancies.
Cytogenetic and genome research 2007;118(2-4):277-83.
2007: A Tyybakinoja; J Vilpo; Sakari Knuutila
High-resolution oligonucleotide array-CGH pinpoints genes involved in cryptic losses in chronic lymphocytic leukemia.
Cytogenetic and genome research 2007;118(1):8-12.
2007: Penny Nymark; Pamela M Lindholm; Mikko V Korpela; Leo Lahti; Salla Ruosaari; Samuel Kaski; Jaakko Hollmén; Sisko Anttila; Vuokko L Kinnula; Sakari Knuutila
Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines.
BMC genomics 2007;8():62.
2007: Sippy Kaur; Marcelo L Larramendy; Hanna Vauhkonen; Tom Böhling; Sakari Knuutila
Loss of TP53 in sarcomas with 17p12 to approximately p11 gain. A fine-resolution oligonucleotide array comparative genomic hybridization study.
Cytogenetic and genome research 2007;116(3):153-7.
2006: Samuel Myllykangas; J Himberg; Tom Böhling; Balint Nagy; Jaakko Hollmén; Sakari Knuutila
DNA copy number amplification profiling of human neoplasms.
Oncogene 2006;25(55):7324-32.
2006: Eeva Kettunen; Kaisa Salmenkivi; Katri Vuopala; Tuula Toljamo; Eeva Kuosma; Hannu Norppa; Sakari Knuutila; Simo Kaleva; Matti S Huuskonen; Sisko Anttila
Copy number gains on 5p15, 6p11-q11, 7p12, and 8q24 are rare in sputum cells of individuals at high risk of lung cancer.
Lung cancer (Amsterdam, Netherlands) 2006;54(2):169-76.
2006: Hanna Vauhkonen; Matti Vauhkonen; Antti Sajantila; Pentti Sipponen; Sakari Knuutila
Characterizing genetically stable and unstable gastric cancers by microsatellites and array comparative genomic hybridization.
Cancer genetics and cytogenetics 2006;170(2):133-9.
2006: Marina Musti; Eeva Kettunen; Silvano Dragonieri; Pamela Lindholm; Domenica Cavone; Gabriella Serio; Sakari Knuutila
Cytogenetic and molecular genetic changes in malignant mesothelioma.
Cancer genetics and cytogenetics 2006;170(1):9-15.
2006: Marcelo L Larramendy; Sippy Kaur; Catarina Svarvar; Tom Böhling; Sakari Knuutila
Gene copy number profiling of soft-tissue leiomyosarcomas by array-comparative genomic hybridization.
Cancer genetics and cytogenetics 2006;169(2):94-101.
2006: Hannu Koistinen; Markku Seppala; Sakari Knuutila; Riitta Koistinen
Extracellular matrix-induced changes in expression of cell cycle-related proteins and proteasome components in endometrial adenocarcinoma cells.
Gynecologic oncology 2006;102(3):546-51.
2006: Catarina Svarvar; Marcelo L Larramendy; Carl Blomqvist; Massimiliano Gentile; Riitta Koivisto-Korander; Arto Leminen; Ralf Bützow; Tom Böhling; Sakari Knuutila
Do DNA copy number changes differentiate uterine from non-uterine leiomyosarcomas and predict metastasis?
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(8):1068-82.
2006: Katri Heikkinen; Katrin Rapakko; Sanna-Maria Karppinen; Hannele Erkko; Sakari Knuutila; Tuija Lundán; Arto Mannermaa; Anne-Lise Børresen-Dale; Ake Borg; Rosa B Barkardottir; John H J Petrini; Robert Winqvist
RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability.
Carcinogenesis 2006;27(8):1593-9.
2006: Nazif Maqani; Abbes Belkhiri; Christopher A Moskaluk; Sakari Knuutila; Altaf A Dar; Wa'el El-Rifai
Molecular dissection of 17q12 amplicon in upper gastrointestinal adenocarcinomas.
Molecular cancer research : MCR 2006;4(7):449-55.
2006: Penny Nymark; Harriet Wikman; Salla Ruosaari; Jaakko Hollmén; Esa Vanhala; Antti Karjalainen; Sisko Anttila; Sakari Knuutila
Identification of specific gene copy number changes in asbestos-related lung cancer.
Cancer research 2006;66(11):5737-43.
2006: Hanna Vauhkonen; Matti Vauhkonen; Antti Sajantila; Pentti Sipponen; Sakari Knuutila
DNA copy number aberrations in intestinal-type gastric cancer revealed by array-based comparative genomic hybridization.
Cancer genetics and cytogenetics 2006;167(2):150-4.
2006: Liisa Lahdelma; Kowan Ja Jee; Grigori Joffe; Evgueni Tchoukhine; Jorma Oksanen; Sippy Kaur; Sakari Knuutila; Leif C Andersson
Altered expression of myeloperoxidase precursor, myeloid cell nuclear differentiation antigen, Fms-related tyrosine kinase 3 ligand, and antigen CD11A genes in leukocytes of clozapine-treated schizophrenic patients.
Journal of clinical psychopharmacology 2006;26(3):335-8.
2006: Virinder K Sarhadi; Harriet Wikman; Kaisa Salmenkivi; Eeva Kuosma; Thanos Sioris; Jarmo Salo; Antti Karjalainen; Sakari Knuutila; Sisko Anttila
Increased expression of high mobility group A proteins in lung cancer.
The Journal of pathology 2006;209(2):206-12.
2006: Maija Tarkkanen; Marcelo L Larramendy; Tom Böhling; Massimo Serra; Claudia M Hattinger; Aarne Kivioja; Inkeri Elomaa; Piero Picci; Sakari Knuutila
Malignant fibrous histiocytoma of bone: analysis of genomic imbalances by comparative genomic hybridisation and C-MYC expression by immunohistochemistry.
European journal of cancer (Oxford, England : 1990) 2006;42(8):1172-80.
2006: Z Wu; Mir S Siadaty; Gregory Riddick; Henry F Frierson; Jae K Lee; W Golden; Sakari Knuutila; Garret M Hampton; Wa'el El-Rifai; Dan Theodorescu
A novel method for gene expression mapping of metastatic competence in human bladder cancer.
Neoplasia (New York, N.Y.) 2006;8(3):181-9.
2006: Anne Tyybäkinoja; Ulla M Saarinen-Pihkala; Erkki Elonen; Sakari Knuutila
Amplified, lost, and fused genes in 11q23-25 amplicon in acute myeloid leukemia, an array-CGH study.
Genes, chromosomes & cancer 2006;45(3):257-64.
2006: Jordi Camps; Gemma Armengol; Javier del Rey; Juan Jose Lozano ; Hanna Vauhkonen; Esther Prat; Josep Egozcue; Lauro Sumoy; Sakari Knuutila; Rosa Miró
Genome-wide differences between microsatellite stable and unstable colorectal tumors.
Carcinogenesis 2006;27(3):419-28.
2006: Aija Knuuttila; Kowan Ja Jee; Eero Taskinen; Henrik Wolff; Sakari Knuutila; Sisko Anttila
Spindle cell tumours of the pleura: a clinical, histological and comparative genomic hybridization analysis of 14 cases.
Virchows Archiv : an international journal of pathology 2006;448(2):135-41.
2006: Samuel Myllykangas; Sakari Knuutila
Manifestation, mechanisms and mysteries of gene amplifications.
Cancer letters 2006;232(1):79-89.
2006: Hanna Vauhkonen; Suvi Savola; Sippy Kaur; Marcelo L Larramendy; Sakari Knuutila
Molecular karyotyping in sarcoma diagnostics and research.
Advances in experimental medicine and biology 2006;587():53-63.
2006: Sippy Kaur; Hanna Vauhkonen; Tom Böhling; F Mertens; N Mandahl; Sakari Knuutila
Gene copy number changes in dermatofibrosarcoma protuberans - a fine-resolution study using array comparative genomic hybridization.
Cytogenetic and genome research 2006;115(3-4):283-8.
2006: Anne Tyybäkinoja; Sakari Knuutila
[Not Available].
Duodecim; lääketieteellinen aikakauskirja 2006;122(16):2018-22.
2006: Milla Mikkola; Cia Olsson; Jaan Palgi; Jarkko Ustinov; Tiina Palomaki; Nina Horelli-Kuitunen; Sakari Knuutila; Karolina Lundin; Timo Otonkoski; Timo Tuuri
Distinct differentiation characteristics of individual human embryonic stem cell lines.
BMC developmental biology 2006;6():40.
2005: Hannu Koistinen; Markku Seppala; Balint Nagy; Johanna Tapper; Sakari Knuutila; Riitta Koistinen
Glycodelin reduces carcinoma-associated gene expression in endometrial adenocarcinoma cells.
American journal of obstetrics and gynecology 2005;193(6):1955-60.
2005: Matjaz Sebenik; Andrew Ricci; Bruno DiPasquale; Kokila Mody; Peter Pytel; Kowan Ja Jee; Sakari Knuutila; John Scholes
Undifferentiated intimal sarcoma of large systemic blood vessels: report of 14 cases with immunohistochemical profile and review of the literature.
The American journal of surgical pathology 2005;29(9):1184-93.
2005: Abbes Belkhiri; Alexander Zaika; Nataliya Pidkovka; Sakari Knuutila; Christopher A Moskaluk; Wa'el El-Rifai
Darpp-32: a novel antiapoptotic gene in upper gastrointestinal carcinomas.
Cancer research 2005;65(15):6583-92.
2005: Sakari Knuutila
A leukemia-enriched cDNA microarray platform identifies new transcripts with relevance to the biology of leukemias.
Haematologica 2005;90(7):866.
2005: Wael M Abdel-Rahman; Miina Ollikainen; Reetta Kariola; Heikki J Järvinen; Jukka-Pekka Mecklin; Minna Nyström-Lahti; Sakari Knuutila; Päivi Peltomäki
Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations.
Oncogene 2005;24(9):1542-51.
2005: Sakari Knuutila
Morphology antibody chromosome technique for determining phenotype and genotype of the same cell.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2005;Chapter 4():Unit 4.7.
2005: Harriet Wikman; Penny Nymark; Aki Väyrynen; Sonata Jarmalaite; Anne Kallioniemi; Kaisa Salmenkivi; Katri Vainio-Siukola; Kirsti Husgafvel-Pursiainen; Sakari Knuutila; Maija Wolf; Sisko Anttila
CDK4 is a probable target gene in a novel amplicon at 12q13.3-q14.1 in lung cancer.
Genes, chromosomes & cancer 2005;42(2):193-9.
2005: Jassu Atiye; Maija Wolf; Sippy Kaur; Outi Monni; Tom Böhling; Aarne Kivioja; Eva Tas; Massimo Serra; Maija Tarkkanen; Sakari Knuutila
Gene amplifications in osteosarcoma-CGH microarray analysis.
Genes, chromosomes & cancer 2005;42(2):158-63.
2005: Wael M Abdel-Rahman; Hannes Lohi; Sakari Knuutila; Päivi Peltomäki
Restoring mismatch repair does not stop the formation of reciprocal translocations in the colon cancer cell line HCA7 but further destabilizes chromosome number.
Oncogene 2005;24(4):706-13.
2005: Ilmo Leivo; Kowan Ja Jee; Kristiina Heikinheimo; Merja Laine; Juha Ollila; Balint Nagy; Sakari Knuutila
Characterization of gene expression in major types of salivary gland carcinomas with epithelial differentiation.
Cancer genetics and cytogenetics 2005;156(2):104-13.
2005: Eeva Kettunen; A G Nicholson; Balint Nagy; Harriet Wikman; Jouni K Seppänen; Tuula Stjernvall; Tiina Ollikainen; Vuokko Kinnula; Stig Nordling; Jaakko Hollmén; Sisko Anttila; Sakari Knuutila
L1CAM, INP10, P-cadherin, tPA and ITGB4 over-expression in malignant pleural mesotheliomas revealed by combined use of cDNA and tissue microarray.
Carcinogenesis 2005;26(1):17-25.
2004: Nina Airla; Mari Luomala; Irina Elovaara; Eeva Kettunen; Sakari Knuutila; Terho Lehtimäki
Suppression of immune system genes by methylprednisolone in exacerbations of multiple sclerosis. Preliminary results.
Journal of neurology 2004;251(10):1215-9.
2004: Claudia M Hattinger; Maija Tarkkanen; Stefania Benini; Michela Pasello; Giuseppina Stoico; Patrizia Bacchini; Sakari Knuutila; Katia Scotlandi; Piero Picci; Massimo Serra
Genetic analysis of fibrosarcoma of bone, a rare tumour entity closely related to osteosarcoma and malignant fibrous histiocytoma of bone.
European journal of cell biology 2004;83(9):483-91.
2004: Anna Ferrer; Juha Ollila; Gerard Tobin; Balint Nagy; Ulf Thunberg; Yan Aalto; Mauno Vihinen; Juhani Vilpo; Richard Rosenquist; Sakari Knuutila
Different gene expression in immunoglobulin-mutated and immunoglobulin-unmutated forms of chronic lymphocytic leukemia.
Cancer genetics and cytogenetics 2004;153(1):69-72.
2004: Samuel Myllykangas; Outi Monni; Balint Nagy; Hilpi Rautelin; Sakari Knuutila
Helicobacter pylori infection activates FOS and stress-response genes and alters expression of genes in gastric cancer-specific loci.
Genes, chromosomes & cancer 2004;40(4):334-41.
2004: Vuokko L Kinnula; Tuula Torkkeli; Paula Kristo; Raija Sormunen; Ylermi Soini; Paavo Pääkkö; Tiina Ollikainen; Katriina Kahlos; Ari Hirvonen; Sakari Knuutila
Ultrastructural and chromosomal studies on manganese superoxide dismutase in malignant mesothelioma.
American journal of respiratory cell and molecular biology 2004;31(2):147-53.
2004: Vanessa Cerisano; Yan Aalto; Stefania Perdichizzi; Ghislaine Bernard; Maria Cristina Manara; Stefania Benini; Giovanna Cenacchi; Paola Preda; Giovanna Lattanzi; Balint Nagy; Sakari Knuutila; Mario P Colombo; Alain Bernard; Piero Picci; Katia Scotlandi
Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: actin and zyxin as key intracellular mediators.
Oncogene 2004;23(33):5664-74.
2004: Eeva Kettunen; Claire Vivo; Florence Gattacceca; Sakari Knuutila; Marie-Claude Jaurand
Gene expression profiles in human mesothelioma cell lines in response to interferon-gamma treatment.
Cancer genetics and cytogenetics 2004;152(1):42-51.
2004: Harriet Wikman; Jouni K Seppänen; Virinder K Sarhadi; Eeva Kettunen; Kaisa Salmenkivi; Eeva Kuosma; Katri Vainio-Siukola; Balint Nagy; Antti Karjalainen; Thanos Sioris; Jarmo Salo; Jaakko Hollmén; Sakari Knuutila; Sisko Anttila
Caveolins as tumour markers in lung cancer detected by combined use of cDNA and tissue microarrays.
The Journal of pathology 2004;203(1):584-93.
2004: Marcelo L Larramendy; Virve Koljonen; Tom Böhling; Erkki Tukiainen; Sakari Knuutila
Recurrent DNA copy number changes revealed by comparative genomic hybridization in primary Merkel cell carcinomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(5):561-7.
2004: Asta Varis; Alexander Zaika; Pauli Puolakkainen; Balint Nagy; Irene Madrigal; Arto Kokkola; Aki Väyrynen; Päivi Kärkkäinen; Christopher A Moskaluk; Wa'el El-Rifai; Sakari Knuutila
Coamplified and overexpressed genes at ERBB2 locus in gastric cancer.
International journal of cancer. Journal international du cancer 2004;109(4):548-53.
2004: Nils Mandahl; Fredrik Mertens; Ioannis Panagopoulos; Sakari Knuutila
Genetic characterization of bone and soft tissue tumors.
Acta orthopaedica Scandinavica. Supplementum 2004;75(311):21-8.
2004: Natalie Koon; Alexander Zaika; Christopher A Moskaluk; Henry F Frierson; Sakari Knuutila; Steven M Powell; Wa'el El-Rifai
Clustering of molecular alterations in gastroesophageal carcinomas.
Neoplasia (New York, N.Y.) 2004;6(2):143-9.
2004: Eeva Kettunen; Sisko Anttila; Jouni K Seppänen; Antti Karjalainen; Henrik Edgren; Irmeli Lindström; Reijo Salovaara; Anna-Maria Nissén; Jarmo Salo; Karin Mattson; Jaakko Hollmén; Sakari Knuutila; Harriet Wikman
Differentially expressed genes in nonsmall cell lung cancer: expression profiling of cancer-related genes in squamous cell lung cancer.
Cancer genetics and cytogenetics 2004;149(2):98-106.
2004: Tuija Lundàn; Liisa Volin; Erkki Elonen; Kirsi Autio; Sakari Knuutila
Clinical and practical value of metaphase fluorescent in situ hybridization in follow-up after allogeneic stem cell transplantation in chronic myeloid leukemia.
Haematologica 2004;89(2):247-9.
2004: Natalie Koon; R Schneider-Stock; Maarit Sarlomo-Rikala; J Lasota; Mark E Smolkin; Gina R Petroni; Alexander Zaika; C Boltze; F Meyer; L Andersson; Sakari Knuutila; M Miettinen; Wa'el El-Rifai
Molecular targets for tumour progression in gastrointestinal stromal tumours.
Gut 2004;53(2):235-40.
2004: Sakari Knuutila
Cytogenetics and molecular pathology in cancer diagnostics.
Annals of medicine 2004;36(3):162-71.
2004: Jukka Kanerva; Ulla M Saarinen-Pihkala; Tarja Niini; Pekka Riikonen; Merja Möttönen; Anne Mäkipernaa; Toivo T Salmi; Kim Vettenranta; Sakari Knuutila
Favorable outcome in 20-year follow-up of children with very-low-risk ALL and minimal standard therapy, with special reference to TEL-AML1 fusion.
Pediatric blood & cancer 2004;42(1):30-5.
2003: Pekka Nieminen; J Kotilainen; Yan Aalto; Sakari Knuutila; Sinikka Pirinen; Irma Thesleff
MSX1 gene is deleted in Wolf-Hirschhorn syndrome patients with oligodontia.
Journal of dental research 2003;82(12):1013-7.
2003: Sanna Aalto; Eeva Juvonen; Jussi Tarkkanen; Liisa Volin; Tapani Ruutu; Petri S Mattila; Heli Piiparinen; Sakari Knuutila; Klaus Hedman
Lymphoproliferative disease after allogeneic stem cell transplantation--pre-emptive diagnosis by quantification of Epstein-Barr virus DNA in serum.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2003;28(3):275-83.
2003: Sílvia Casas; Balint Nagy; Erkki Elonen; Anna Aventín; Marcelo L Larramendy; Jorge Sierra; Tapani Ruutu; Sakari Knuutila
Aberrant expression of HOXA9, DEK, CBL and CSF1R in acute myeloid leukemia.
Leukemia & lymphoma 2003;44(11):1935-41.
2003: Yuntao Xie; Maria Törnkvist; Yan Aalto; Gunnar Nilsson; Leonard Girnita; Balint Nagy; Sakari Knuutila; Olle Larsson
Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene.
Oncogene 2003;22(48):7628-31.
2003: Sílvia Casas; Juha Ollila; Anna Aventín; Mauno Vihinen; Jorge Sierra; Sakari Knuutila
Changes in apoptosis-related pathways in acute myelocytic leukemia.
Cancer genetics and cytogenetics 2003;146(2):89-101.
2003: Kajsa Paulsson; Ioannis Panagopoulos; Sakari Knuutila; Kowan Ja Jee; Stanislaw Garwicz; Thoas Fioretos; Felix Mitelman; Bertil Johansson
Formation of trisomies and their parental origin in hyperdiploid childhood acute lymphoblastic leukemia.
Blood 2003;102(8):3010-5.
2003: Petter Brandal; Francesca Micci; Bodil Bjerkehagen; Mette Eknaes; Marcelo L Larramendy; Ragnhild A Lothe; Sakari Knuutila; Sverre Heim
Molecular cytogenetic characterization of desmoid tumors.
Cancer genetics and cytogenetics 2003;146(1):1-7.
2003: Ritva Karhu; Gerard Tobin; Ulf Thunberg; Leena Vilpo; Christer Sundström; Sakari Knuutila; Richard Rosenquist; Juhani Vilpo
More extensive genetic alterations in unmutated than in hypermutated cases of chronic lymphocytic leukemia.
Genes, chromosomes & cancer 2003;37(4):417-20.
2003: Meerit Kämäräinen; Kukka Heiskala; Sakari Knuutila; Marja Heiskala; Ola Winqvist; Leif C Andersson
RELP, a novel human REG-like protein with up-regulated expression in inflammatory and metaplastic gastrointestinal mucosa.
The American journal of pathology 2003;163(1):11-20.
2003: Eeva Juvonen; Sanna Aalto; Jussi Tarkkanen; Liisa Volin; Petri S Mattila; Sakari Knuutila; Tapani Ruutu; Klaus Hedman
High incidence of PTLD after non-T-cell-depleted allogeneic haematopoietic stem cell transplantation as a consequence of intensive immunosuppressive treatment.
Bone marrow transplantation 2003;32(1):97-102.
2003: Asta Varis; Bastiaan P van Rees; M Weterman; A Ristimäki; G Johan A Offerhaus; Sakari Knuutila
DNA copy number changes in young gastric cancer patients with special reference to chromosome 19.
British journal of cancer 2003;88(12):1914-9.
2003: Balint Nagy; Anna Ferrer; Marcelo L Larramendy; Sara Galimberti; Yan Aalto; Sílvia Casas; Juhani Vilpo; Tapani Ruutu; Kim Vettenranta; Kaarle Franssila; Sakari Knuutila
Lymphotoxin beta expression is high in chronic lymphocytic leukemia but low in small lymphocytic lymphoma: a quantitative real-time reverse transcriptase polymerase chain reaction analysis.
Haematologica 2003;88(6):654-8.
2003: Päivi Laiho; Tuija Hienonen; Auli Karhu; Lara Lipton; Yan Aalto; Huw J W Thomas; Karin Birkenkamp-Demtroder; Shirley Hodgson; Reijo Salovaara; Jukka-Pekka Mecklin; Heikki Järvinen; Sakari Knuutila; Stephanie Halford; Torben F Ørntoft; Ian Tomlinson; Virpi Launonen; richard Houlston; Lauri A Aaltonen
Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases.
Oncogene 2003;22(14):2206-14.
2003: Silvina M Richard; Sakari Knuutila; Päivi Peltomäki; Martha S Bianchi; Néstor O Bianchi
Y chromosome instability in lymphoproliferative disorders.
Mutation research 2003;525(1-2):103-7.
2003: Ren Wei Chen; Yan Aalto; Tambet Teesalu; M Dürst; Sakari Knuutila; Leena-Maija Aaltonen; Antti Vaheri
Establishment and characterisation of human papillomavirus type 16 DNA immortalised human tonsillar epithelial cell lines.
European journal of cancer (Oxford, England : 1990) 2003;39(5):698-707.
2003: Balint Nagy; Tuija Lundán; Marcelo L Larramendy; Yan Aalto; Ying Zhu; Tarja Niini; Henrik Edgren; Anna Ferrer; Juhani Vilpo; Erkki Elonen; Kim Vettenranta; Kaarle Franssila; Sakari Knuutila
Abnormal expression of apoptosis-related genes in haematological malignancies: overexpression of MYC is poor prognostic sign in mantle cell lymphoma.
British journal of haematology 2003;120(3):434-41.
2003: Kowan Ja Jee; Gyungyub Gong; Sei Hyun Ahn; Jeong Mi Park; Sakari Knuutila
Gain in 1q is a common abnormality in phyllodes tumours of the breast.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2003;25(2):89-93.
2003: Veli-Matti Wasenius; Samuli Hemmer; Eeva Kettunen; Sakari Knuutila; Kaarle Franssila; Heikki Joensuu
Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are up-regulated in papillary thyroid carcinoma: a cDNA and tissue microarray study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(1):68-75.
2002: Maaike van Dartel; Peter W A Cornelissen; Sandra Redeker; Maija Tarkkanen; Sakari Knuutila; Pancras Hogendoorn; Andries Westerveld; Ingrid Gomes; Johannes Bras; Theo J M Hulsebos
Amplification of 17p11.2 approximately p12, including PMP22, TOP3A, and MAPK7, in high-grade osteosarcoma.
Cancer genetics and cytogenetics 2002;139(2):91-6.
2002: Ying Zhu; Jaakko Hollmén; Riikka Räty; Yan Aalto; Balint Nagy; Erkki Elonen; Juha Kere; Heikki Mannila; Kaarle Franssila; Sakari Knuutila
Investigatory and analytical approaches to differential gene expression profiling in mantle cell lymphoma.
British journal of haematology 2002;119(4):905-15.
2002: Tarja Niini; Kim Vettenranta; Jaakko Hollmén; Marcelo L Larramendy; Yan Aalto; Harriet Wikman; Balint Nagy; Jouni K Seppänen; A Ferrer Salvador; Heikki Mannila; Ulla M Saarinen-Pihkala; Sakari Knuutila
Expression of myeloid-specific genes in childhood acute lymphoblastic leukemia - a cDNA array study.
Leukemia 2002;16(11):2213-21.
2002: Xing Fan; Yan Aalto; Stephen G Sanko; Sakari Knuutila; David Klatzmann; Javier S Castresana
Genetic profile, PTEN mutation and therapeutic role of PTEN in glioblastomas.
International journal of oncology 2002;21(5):1141-50.
2002: Marina Musti; Domenica Cavone; Yan Aalto; Anna Scattone; Gabriella Serio; Sakari Knuutila
A cluster of familial malignant mesothelioma with del(9p) as the sole chromosomal anomaly.
Cancer genetics and cytogenetics 2002;138(1):73-6.
2002: Hakan Savli; Yan Aalto; Balint Nagy; Sakari Knuutila; Seppo Pakkala
Gene expression analysis of 1,25(OH)2D3-dependent differentiation of HL-60 cells: a cDNA array study.
British journal of haematology 2002;118(4):1065-70.
2002: Harriet Wikman; Eeva Kettunen; Jouni K Seppänen; Antti Karjalainen; Jaakko Hollmén; Sisko Anttila; Sakari Knuutila
Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array.
Oncogene 2002;21(37):5804-13.
2002: Maija Kiuru; Rainer Lehtonen; Johanna Arola; Reijo Salovaara; Heikki Järvinen; Kristiina Aittomäki; Jari Sjöberg; Tapio Visakorpi; Sakari Knuutila; Jorma Isola; Brett Delahunt; Riitta Herva; Virpi Launonen; Auli Karhu; Lauri A Aaltonen
Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families.
Cancer research 2002;62(16):4554-7.
2002: Kristiina Heikinheimo; Kowan Ja Jee; Tarja Niini; Yan Aalto; Risto-Pekka Happonen; Ilmo Leivo; Sakari Knuutila
Gene expression profiling of ameloblastoma and human tooth germ by means of a cDNA microarray.
Journal of dental research 2002;81(8):525-30.
2002: Wa'el El-Rifai; Michael Smith, Jr.; Guolian Li; Andy Beckler; Virginia S Carl; Elizabeth Montgomery; Sakari Knuutila; Christopher A Moskaluk; Henry F Frierson; Steven M Powell
Gastric cancers overexpress DARPP-32 and a novel isoform, t-DARPP.
Cancer research 2002;62(14):4061-4.
2002: Karoliina Jääskeläinen; Kowan Ja Jee; Ilmo Leivo; Irma Saloniemi; Sakari Knuutila; Kristiina Heikinheimo
Cell proliferation and chromosomal changes in human ameloblastoma.
Cancer genetics and cytogenetics 2002;136(1):31-7.
2002: Ritva Karhu; Leena Vilpo; Jorma Isola; Sakari Knuutila; Juhani Vilpo
Cryopreserved chronic lymphocytic leukemia cells analyzed by multicolor fluorescence in situ hybridization after optimized mitogen stimulation.
Genes, chromosomes & cancer 2002;34(3):345-8.
2002: Claudia M Hattinger; Ulrike Pötschger; Maija Tarkkanen; Jeremy Squire; Maria Zielenska; S Kiuru-Kuhlefelt; Leo Kager; P Thorner; Sakari Knuutila; Felix K Niggli; Peter F Ambros; Helmut Gadner; D R Betts
Prognostic impact of chromosomal aberrations in Ewing tumours.
British journal of cancer 2002;86(11):1763-9.
2002: Kim Vettenranta; Kirsi Autio; Liisa Hovi; Sakari Knuutila; Ulla M Saarinen-Pihkala
Follow-up of minimal residual disease in pediatric acute myeloblastic leukemia using metaphase-FISH.
Leukemia & lymphoma 2002;43(6):1261-5.
2002: Marcelo L Larramendy; Tarja Niini; Erkki Elonen; Balint Nagy; Juha Ollila; Mauno Vihinen; Sakari Knuutila
Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis.
Haematologica 2002;87(6):569-77.
2002: Jukka Kanerva; Kim Vettenranta; Kirsi Autio; Sakari Knuutila; Ulla M Saarinen-Pihkala
Minimal residual disease by metaphase FISH in children with ALL: clonal cells during or after chemotherapy may not predict relapse.
Leukemia research 2002;26(6):545-50.
2002: Asta Varis; Maija Wolf; Outi Monni; Marja-Leena Vakkari; Arto Kokkola; Christopher A Moskaluk; Henry F Frierson; Steven M Powell; Sakari Knuutila; Anne Kallioniemi; Wa'el El-Rifai
Targets of gene amplification and overexpression at 17q in gastric cancer.
Cancer research 2002;62(9):2625-9.
2002: Samuli Hemmer; Veli-Matti Wasenius; Caj Haglund; Ying Zhu; Sakari Knuutila; Kaarle Franssila; Heikki Joensuu
Alterations in the suppressor gene PPP2R1B in parathyroid hyperplasias and adenomas.
Cancer genetics and cytogenetics 2002;134(1):13-7.
2002: Irmeli Lindström; Stig Nordling; Anna-Maria Nissén; Lauri Tammilehto; Karin Mattson; Sakari Knuutila
DNA copy number changes in lung adenocarcinoma in younger patients.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2002;15(4):372-8.
2002: Leonardo A. Meza-Zepeda; Anne Forus; Birgitte Lygren; Anine B Dahlberg; Linda H Godager; Andrew P South; Ingo Marenholz; Maria Lioumi; Vivi Ann Flørenes; Gunhild M Maelandsmo; Massimo Serra; Dietmar Mischke; Dean Nizetic; Jiannis Ragoussis; Maija Tarkkanen; Jahn M Nesland; Sakari Knuutila; Ola Myklebost
Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21.
Oncogene 2002;21(14):2261-9.
2002: Sebsebe Lemeta; Yan Aalto; Mika Niemelä; Juha Jääskeläinen; Markku Sainio; Juha Kere; Sakari Knuutila; Tom Böhling
Recurrent DNA sequence copy losses on chromosomal arm 6q in capillary hemangioblastoma.
Cancer genetics and cytogenetics 2002;133(2):174-8.
2002: Nils Mandahl; Pelle Gustafson; Fredrik Mertens; Måns Akerman; Bo Baldetorp; David Gisselsson; Sakari Knuutila; Henrik C F Bauer; Olle Larsson
Cytogenetic aberrations and their prognostic impact in chondrosarcoma.
Genes, chromosomes & cancer 2002;33(2):188-200.
2001: Jukka Kanerva; Tarja Niini; Kim Vettenranta; Pekka Riikonen; Anne Mäkipernaa; Ritva Karhu; Sakari Knuutila; Ulla M Saarinen-Pihkala
Loss at 12p detected by comparative genomic hybridization (CGH): association with TEL-AML1 fusion and favorable prognostic features in childhood acute lymphoblastic leukemia (ALL). A multi-institutional study.
Medical and pediatric oncology 2001;37(5):419-25.
2001: Yan Aalto; W El-Rifa; Leena Vilpo; Juha Ollila; Balint Nagy; Mauno Vihinen; Juhani Vilpo; Sakari Knuutila
Distinct gene expression profiling in chronic lymphocytic leukemia with 11q23 deletion.
Leukemia 2001;15(11):1721-8.
2001: Pentscho Popov; Martti Virolainen; Erkki Tukiainen; S Asko-Scljavaara; Riikka Huuhtanen; Sakari Knuutila; Maija Tarkkanen
Primary soft tissue sarcoma and its local recurrence: genetic changes studied by comparative genomic hybridization.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001;14(10):978-84.
2001: S Rantanen; Outi Monni; Heikki Joensuu; Kaarle Franssila; Sakari Knuutila
Causes and consequences of BCL2 overexpression in diffuse large B-cell lymphoma.
Leukemia & lymphoma 2001;42(5):1089-98.
2001: Wa'el El-Rifai; Henry F Frierson; Christopher A Moskaluk; Jeffrey C Harper; Gina R Petroni; Eric A Bissonette; D R Jones; Sakari Knuutila; Steven M Powell
Genetic differences between adenocarcinomas arising in Barrett's esophagus and gastric mucosa.
Gastroenterology 2001;121(3):592-8.
2001: Johanna Tapper; Eeva Kettunen; Wa'el El-Rifai; Markku Seppala; Leif C Andersson; Sakari Knuutila
Changes in gene expression during progression of ovarian carcinoma.
Cancer genetics and cytogenetics 2001;128(1):1-6.
2001: Wa'el El-Rifai; Henry F Frierson; Jeffrey C Harper; S M Powell; Sakari Knuutila
Expression profiling of gastric adenocarcinoma using cDNA array.
International journal of cancer. Journal international du cancer 2001;92(6):832-8.
2001: Wa'el El-Rifai; Sue Rutherford; Sakari Knuutila; Henry F Frierson; Christopher A Moskaluk
Novel DNA copy number losses in chromosome 12q12--q13 in adenoid cystic carcinoma.
Neoplasia (New York, N.Y.) 2001;3(3):173-8.
2001: Asta Varis; Pauli Puolakkainen; H Savolainen; Arto Kokkola; Jarmo Salo; O Nieminen; Stig Nordling; Sakari Knuutila
DNA copy number profiling in esophageal Barrett adenocarcinoma: comparison with gastric adenocarcinoma and esophageal squamous cell carcinoma.
Cancer genetics and cytogenetics 2001;127(1):53-8.
2001: S Menghi-Sartorio; N Mandahl; F Mertens; Piero Picci; Sakari Knuutila
DNA copy number amplifications in sarcomas with homogeneously staining regions and double minutes.
Cytometry 2001;46(2):79-84.
2001: Samuli Hemmer; Veli-Matti Wasenius; Caj Haglund; Ying Zhu; Sakari Knuutila; Kaarle Franssila; Heikki Joensuu
Deletion of 11q23 and cyclin D1 overexpression are frequent aberrations in parathyroid adenomas.
The American journal of pathology 2001;158(4):1355-62.
2001: Kim Vettenranta; Yan Aalto; Sakari Wikström; Sakari Knuutila; Ulla M Saarinen-Pihkala
Comparative genomic hybridization reveals changes in DNA-copy number in poor-risk neuroblastoma.
Cancer genetics and cytogenetics 2001;125(2):125-30.
2001: Anne Forus; Marcelo L Larramendy; Leonardo A. Meza-Zepeda; Bodil Bjerkehagen; Linda H Godager; Anine B Dahlberg; Gunnar Saeter; Sakari Knuutila; Ola Myklebost
Dedifferentiation of a well-differentiated liposarcoma to a highly malignant metastatic osteosarcoma: amplification of 12q14 at all stages and gain of 1q22-q24 associated with metastases.
Cancer genetics and cytogenetics 2001;125(2):100-11.
2001: Ying Zhu; Anu Loukola; Outi Monni; K Kuokkanen; Kaarle Franssila; Erkki Elonen; Juhani Vilpo; Heikki Joensuu; Juha Kere; L Aaltonen; Sakari Knuutila
PPP2R1B gene in chronic lymphocytic leukemias and mantle cell lymphomas.
Leukemia & lymphoma 2001;41(1-2):177-83.
2001: Eeva Kettunen; Anna-Maria Nissén; Tiina Ollikainen; M Taavitsainen; Johanna Tapper; Karin Mattson; Kaija Linnainmaa; Sakari Knuutila; Wa'el El-Rifai
Gene expression profiling of malignant mesothelioma cell lines: cDNA array study.
International journal of cancer. Journal international du cancer 2001;91(4):492-6.
2001: Yan Aalto; L Eriksson; S Seregard; Olle Larsson; Sakari Knuutila
Concomitant loss of chromosome 3 and whole arm losses and gains of chromosome 1, 6, or 8 in metastasizing primary uveal melanoma.
Investigative ophthalmology & visual science 2001;42(2):313-7.
2001: Wa'el El-Rifai; Sakari Knuutila
Genetic analysis using microarrays.
Methods in molecular medicine 2001;50():195-203.
2001: Wa'el El-Rifai; Sakari Knuutila
Comparative genomic hybridization technique.
Methods in molecular medicine 2001;50():25-33.
2001: Kowan Ja Jee; Y T Kim; K R Kim; Yan Aalto; Sakari Knuutila
Amplification at 9p in cervical carcinoma by comparative genomic hybridization.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2001;22(3):159-63.
2001: S Kiuru-Kuhlefelt; Wa'el El-Rifai; J Fanburg-Smith; Juha Kere; Markku Miettinen; Sakari Knuutila
Concomitant DNA copy number amplification at 17q and 22q in dermatofibrosarcoma protuberans.
Cytogenetics and cell genetics 2001;92(3-4):192-5.
2000: M Wolf; Wa'el El-Rifai; Maija Tarkkanen; Juha Kononen; M Serra; Erik Fink Eriksen; Inkeri Elomaa; Anne Kallioniemi; Olli Kallioniemi; Sakari Knuutila
Novel findings in gene expression detected in human osteosarcoma by cDNA microarray.
Cancer genetics and cytogenetics 2000;123(2):128-32.
2000: T Lushnikova; Sakari Knuutila; Markku Miettinen
DNA copy number changes in epithelioid sarcoma and its variants: a comparative genomic hybridization study.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2000;13(10):1092-6.
2000: Ying Zhu; Outi Monni; Kaarle Franssila; Erkki Elonen; Juhani Vilpo; Heikki Joensuu; Sakari Knuutila
Deletions at 11q23 in different lymphoma subtypes.
Haematologica 2000;85(9):908-12.
2000: E Stumpf; Yan Aalto; Anders Höög; Magnus Kjellman; Timo Otonkoski; Sakari Knuutila; Leif C Andersson
Chromosomal alterations in human pancreatic endocrine tumors.
Genes, chromosomes & cancer 2000;29(1):83-7.
2000: Sakari Knuutila; Kirsi Autio; Yan Aalto
Online access to CGH data of DNA sequence copy number changes.
The American journal of pathology 2000;157(2):689.
2000: Wa'el El-Rifai; Maarit Sarlomo-Rikala; Leif C Andersson; Sakari Knuutila; M Miettinen
DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significance.
Cancer research 2000;60(14):3899-903.
2000: Tomi Koski; Ritva Karhu; T Visakorpi; Leena Vilpo; Sakari Knuutila; Juhani Vilpo
Complex chromosomal aberrations in chronic lymphocytic leukemia are associated with cellular drug and irradiation resistance.
European journal of haematology 2000;65(1):32-9.
2000: Marcelo L Larramendy; T Lushnikova; AM Björkqvist; I I Wistuba; A K Virmani; Narayan Shivapurkar; A F Gazdar; Sakari Knuutila
Comparative genomic hybridization reveals complex genetic changes in primary breast cancer tumors and their cell lines.
Cancer genetics and cytogenetics 2000;119(2):132-8.
2000: S Kiuru-Kuhlefelt; Maarit Sarlomo-Rikala; Marcelo L Larramendy; M Söderlund; K Hedman; Markku Miettinen; Sakari Knuutila
FGF4 and INT2 oncogenes are amplified and expressed in Kaposi's sarcoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2000;13(4):433-7.
2000: Tarja Niini; Jukka Kanerva; Kim Vettenranta; Ulla M Saarinen-Pihkala; Sakari Knuutila
AML1 gene amplification: a novel finding in childhood acute lymphoblastic leukemia.
Haematologica 2000;85(4):362-6.
2000: Wa'el El-Rifai; Maarit Sarlomo-Rikala; Leif C Andersson; Markku Miettinen; Sakari Knuutila
High-resolution deletion mapping of chromosome 14 in stromal tumors of the gastrointestinal tract suggests two distinct tumor suppressor loci.
Genes, chromosomes & cancer 2000;27(4):387-91.
2000: Wa'el El-Rifai; D Kamel; Marcelo L Larramendy; yehia gad; Y Gad; S Baithun; Mostafa El Awady; Saad Eissa; Hussein M Khaled; Sonia Soloneski; M Sheaff; Sakari Knuutila
DNA copy number changes in Schistosoma-associated and non-Schistosoma-associated bladder cancer.
The American journal of pathology 2000;156(3):871-8.
2000: Eeva Kettunen; Wa'el El-Rifai; AM Björkqvist; H Wolff; Antti Karjalainen; Sisko Anttila; Karin Mattson; Kirsti Husgafvel-Pursiainen; Sakari Knuutila
A broad amplification pattern at 3q in squamous cell lung cancer--a fluorescence in situ hybridization study.
Cancer genetics and cytogenetics 2000;117(1):66-70.
2000: Gemma Armengol; Sakari Knuutila; Fèlix Lluís; Gabriel Capellà; Rosa Miró; Maria Rosa Caballín
DNA copy number changes and evaluation of MYC, IGF1R, and FES amplification in xenografts of pancreatic adenocarcinoma.
Cancer genetics and cytogenetics 2000;116(2):133-41.
2000: Fredrik Mertens; Marcelo L Larramendy; Anita Gustavsson; David Gisselsson; Anders Rydholm; Otte Brosjö; Felix Mitelman; Sakari Knuutila; Nils Mandahl
Radiation-associated sarcomas are characterized by complex karyotypes with frequent rearrangements of chromosome arm 3p.
Cancer genetics and cytogenetics 2000;116(2):89-96.
1999: AM Björkqvist; M Wolf; Stig Nordling; Lauri Tammilehto; Aija Knuuttila; Juha Kere; Karin Mattson; Sakari Knuutila
Deletions at 14q in malignant mesothelioma detected by microsatellite marker analysis.
British journal of cancer 1999;81(7):1111-5.
1999: Björn Skytting; J Szymanska; Yan Aalto; T Lushnikova; Carl Blomqvist; Inkeri Elomaa; Olle Larsson; Sakari Knuutila
Clinical importance of genomic imbalances in synovial sarcoma evaluated by comparative genomic hybridization.
Cancer genetics and cytogenetics 1999;115(1):39-46.
1999: T Huhta; Kim Vettenranta; Kirsti Heinonen; Jukka Kanerva; Marcelo L Larramendy; Eija H Mahlamäki; Ulla M Saarinen-Pihkala; Sakari Knuutila
Comparative genomic hybridization and conventional cytogenetic analyses in childhood acute myeloid leukemia.
Leukemia & lymphoma 1999;35(3-4):311-5.
1999: Marcelo L Larramendy; N Mandahl; F Mertens; Carl Blomqvist; Aarne Kivioja; Erkki O Karaharju; J Valle; Tom Böhling; Maija Tarkkanen; A Rydholm; Måns Akerman; Henrik C F Bauer; J P Anttila; Inkeri Elomaa; Sakari Knuutila
Clinical significance of genetic imbalances revealed by comparative genomic hybridization in chondrosarcomas.
Human pathology 1999;30(10):1247-53.
1999: Maija Tarkkanen; S Kiuru-Kuhlefelt; Carl Blomqvist; Gemma Armengol; Tom Böhling; Tauno O Ekfors; Martti Virolainen; P Lindholm; OR Monge; Piero Picci; Sakari Knuutila; Inkeri Elomaa
Clinical correlations of genetic changes by comparative genomic hybridization in Ewing sarcoma and related tumors.
Cancer genetics and cytogenetics 1999;114(1):35-41.
1999: Sakari Knuutila; Yan Aalto; Kirsi Autio; AM Björkqvist; Wa'el El-Rifai; Samuli Hemmer; T Huhta; Eeva Kettunen; S Kiuru-Kuhlefelt; Marcelo L Larramendy; T Lushnikova; Outi Monni; H Pere; Johanna Tapper; Maija Tarkkanen; Asta Varis; Veli-Matti Wasenius; M Wolf; Ying Zhu
DNA copy number losses in human neoplasms.
The American journal of pathology 1999;155(3):683-94.
1999: Maija Tarkkanen; Riikka Huuhtanen; Martti Virolainen; Tom Wiklund; Sirpa Asko-Seljavaara; Erkki Tukiainen; M Lepäntalo; Inkeri Elomaa; Sakari Knuutila
Comparison of genetic changes in primary sarcomas and their pulmonary metastases.
Genes, chromosomes & cancer 1999;25(4):323-31.
1999: M Wolf; Maija Tarkkanen; Theo J M Hulsebos; Marcelo L Larramendy; Anne Forus; Ola Myklebost; Lauri A Aaltonen; Inkeri Elomaa; Sakari Knuutila
Characterization of the 17p amplicon in human sarcomas: microsatellite marker analysis.
International journal of cancer. Journal international du cancer 1999;82(3):329-33.
1999: Wa'el El-Rifai; L Tarmo; Samuli Hemmer; Asta Försti; N Pedersen; Paul Lichtenstein; A Ahlbom; Magnus Söderberg; Sakari Knuutila; Kari Hemminki
DNA copy number losses at 1p32-pter in monozygotic twins concordant for breast cancer.
Cancer genetics and cytogenetics 1999;112(2):169-72.
1999: Outi Monni; Kaarle Franssila; Heikki Joensuu; Sakari Knuutila
BCL2 overexpression in diffuse large B-cell lymphoma.
Leukemia & lymphoma 1999;34(1-2):45-52.
1999: Yan Aalto; Stig Nordling; Aarne Kivioja; Erkki O Karaharju; Inkeri Elomaa; Sakari Knuutila
Among numerous DNA copy number changes, losses of chromosome 13 are highly recurrent in plasmacytoma.
Genes, chromosomes & cancer 1999;25(2):104-7.
1999: Ying Zhu; Outi Monni; Wa'el El-Rifai; Sanna Siitonen; Leena Vilpo; Juhani Vilpo; Sakari Knuutila
Discontinuous deletions at 11q23 in B cell chronic lymphocytic leukemia.
Leukemia 1999;13(5):708-12.
1999: Samuli Hemmer; Veli-Matti Wasenius; Sakari Knuutila; Kaarle Franssila; Heikki Joensuu
DNA copy number changes in thyroid carcinoma.
The American journal of pathology 1999;154(5):1539-47.
1999: Maija Tarkkanen; Inkeri Elomaa; Carl Blomqvist; Aarne Kivioja; P Kellokumpu-Lehtinen; Tom Böhling; J Valle; Sakari Knuutila
DNA sequence copy number increase at 8q: a potential new prognostic marker in high-grade osteosarcoma.
International journal of cancer. Journal international du cancer 1999;84(2):114-21.
1999: Outi Monni; Ying Zhu; Kaarle Franssila; Riikka Oinonen; P Höglund; Erkki Elonen; Heikki Joensuu; Sakari Knuutila
Molecular characterization of deletion at 11q22.1-23.3 in mantle cell lymphoma.
British journal of haematology 1999;104(4):665-71.
1999: V Vidgren; Asta Varis; Arto Kokkola; Outi Monni; Pauli Puolakkainen; Stig Nordling; F Forozan; Anne Kallioniemi; M L Vakkari; Eero Kivilaakso; Sakari Knuutila
Concomitant gastrin and ERBB2 gene amplifications at 17q12-q21 in the intestinal type of gastric cancer.
Genes, chromosomes & cancer 1999;24(1):24-9.
1998: Arto Kokkola; Outi Monni; Pauli Puolakkainen; Stig Nordling; Reijo Haapiainen; Eero Kivilaakso; Sakari Knuutila
Presence of high-level DNA copy number gains in gastric carcinoma and severely dysplastic adenomas but not in moderately dysplastic adenomas.
Cancer genetics and cytogenetics 1998;107(1):32-6.
1998: J Szymanska; M Serra; Björn Skytting; Olle Larsson; Martti Virolainen; Måns Akerman; Maija Tarkkanen; Riikka Huuhtanen; Piero Picci; P Bacchini; Sirpa Asko-Seljavaara; Inkeri Elomaa; Sakari Knuutila
Genetic imbalances in 67 synovial sarcomas evaluated by comparative genomic hybridization.
Genes, chromosomes & cancer 1998;23(3):213-9.
1998: Marcelo L Larramendy; T Huhta; Kirsti Heinonen; Kim Vettenranta; Eija H Mahlamäki; Pekka Riikonen; Ulla M Saarinen-Pihkala; Sakari Knuutila
DNA copy number changes in childhood acute lymphoblastic leukemia.
Haematologica 1998;83(10):890-5.
1998: Samuli Hemmer; Veli-Matti Wasenius; Sakari Knuutila; Heikki Joensuu; Kaarle Franssila
Comparison of benign and malignant follicular thyroid tumours by comparative genomic hybridization.
British journal of cancer 1998;78(8):1012-7.
1998: Marcelo L Larramendy; Wa'el El-Rifai; Arto Kokkola; Pauli Puolakkainen; Outi Monni; Reijo Salovaara; Markku T Aarnio; Sakari Knuutila
Comparative genomic hybridization reveals differences in DNA copy number changes between sporadic gastric carcinomas and gastric carcinomas from patients with hereditary nonpolyposis colorectal cancer.
Cancer genetics and cytogenetics 1998;106(1):62-5.
1998: H Pere; Johanna Tapper; Markku Seppala; Sakari Knuutila; Ralf Butzow
Genomic alterations in fallopian tube carcinoma: comparison to serous uterine and ovarian carcinomas reveals similarity suggesting likeness in molecular pathogenesis.
Cancer research 1998;58(19):4274-6.
1998: Marcelo L Larramendy; T Huhta; Kim Vettenranta; Wa'el El-Rifai; Johan Lundin; Seppo Pakkala; Ulla M Saarinen-Pihkala; Sakari Knuutila
Comparative genomic hybridization in childhood acute lymphoblastic leukemia.
Leukemia 1998;12(10):1638-44.
1998: Marcelo L Larramendy; Martti Virolainen; Erkki Tukiainen; Inkeri Elomaa; Sakari Knuutila
Chromosome band 1q21 is recurrently gained in desmoid tumors.
Genes, chromosomes & cancer 1998;23(2):183-6.
1998: Wa'el El-Rifai; Maarit Sarlomo-Rikala; Sakari Knuutila; Markku Miettinen
DNA copy number changes in development and progression in leiomyosarcomas of soft tissues.
The American journal of pathology 1998;153(3):985-90.
1998: Jukka Tienari; I Reima; Marcelo L Larramendy; Sakari Knuutila; Kristina von Boguslawsky; M Kaartinen; Ismo Virtanen; Eero Lehtonen
A cloned human germ cell tumor-derived cell line differentiating in culture.
International journal of cancer. Journal international du cancer 1998;77(5):710-9.
1998: Kirsi Autio; Yan Aalto; Kaarle Franssila; Erkki Elonen; Heikki Joensuu; Sakari Knuutila
Low number of DNA copy number changes in small lymphocytic lymphoma.
Haematologica 1998;83(8):690-2.
1998: Johanna Tapper; Laura Sarantaus; Pia Vahteristo; Heli Nevanlinna; Samuli Hemmer; Markku Seppala; Sakari Knuutila; Ralf Butzow
Genetic changes in inherited and sporadic ovarian carcinomas by comparative genomic hybridization: extensive similarity except for a difference at chromosome 2q24-q32.
Cancer research 1998;58(13):2715-9.
1998: Maija Tarkkanen; Tom Böhling; Gabriella Gamberi; Paola Ragazzini; M S Benassi; Aarne Kivioja; P Kallio; Inkeri Elomaa; Piero Picci; Sakari Knuutila
Comparative genomic hybridization of low-grade central osteosarcoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1998;11(5):421-6.
1998: Maarit Sarlomo-Rikala; Wa'el El-Rifai; Tapani Lahtinen; Leif C Andersson; Markku Miettinen; Sakari Knuutila
Different patterns of DNA copy number changes in gastrointestinal stromal tumors, leiomyomas, and schwannomas.
Human pathology 1998;29(5):476-81.
1998: AM Björkqvist; Kirsti Husgafvel-Pursiainen; Sisko Anttila; Antti Karjalainen; Lauri Tammilehto; Karin Mattson; Harri Vainio; Sakari Knuutila
DNA gains in 3q occur frequently in squamous cell carcinoma of the lung, but not in adenocarcinoma.
Genes, chromosomes & cancer 1998;22(1):79-82.
1998: Sakari Knuutila; AM Björkqvist; Kirsi Autio; Maija Tarkkanen; M Wolf; Outi Monni; J Szymanska; Marcelo L Larramendy; Johanna Tapper; H Pere; Wa'el El-Rifai; Samuli Hemmer; Veli-Matti Wasenius; V Vidgren; Ying Zhu
DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies.
The American journal of pathology 1998;152(5):1107-23.
1998: H Attalla; Sakari Knuutila; Tomi Mäkelä; Leif C Andersson; Herman Adlercreutz
Cytogenetic chromosomal preparations using 2-methoxyestradiol.
Cancer genetics and cytogenetics 1998;102(2):139-41.
1998: Outi Monni; Riikka Oinonen; Erkki Elonen; Kaarle Franssila; Lasse Teerenhovi; Heikki Joensuu; Sakari Knuutila
Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphoma.
Genes, chromosomes & cancer 1998;21(4):298-307.
1998: Kim Vettenranta; T Huhta; M Lindlöf; Sakari Knuutila; Ulla M Saarinen-Pihkala
Combined RT-PCR and metaphase-FISH posttransplant studies in pediatric patients with chronic myeloid leukemia.
Journal of pediatric hematology/oncology 1998;20(2):108-11.
1998: S Kiuru-Kuhlefelt; Wa'el El-Rifai; Maarit Sarlomo-Rikala; Sakari Knuutila; Markku Miettinen
DNA copy number changes in alveolar soft part sarcoma: a comparative genomic hybridization study.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1998;11(3):227-31.
1998: Marcelo L Larramendy; Wa'el El-Rifai; Sakari Knuutila
Comparison of fluorescein isothiocyanate- and Texas red-conjugated nucleotides for direct labeling in comparative genomic hybridization.
Cytometry 1998;31(3):174-9.
1998: H Pere; Johanna Tapper; Torsten Wahlström; Sakari Knuutila; Ralf Butzow
Distinct chromosomal imbalances in uterine serous and endometrioid carcinomas.
Cancer research 1998;58(5):892-5.
1998: M Wolf; Akseli Hemminki; Aarne Kivioja; Pertti Sistonen; Ilkka Kaitila; H Ervasti; Jaakko Kinnunen; Erkki O Karaharju; Sakari Knuutila
A novel splice site mutation of the EXT2 gene in a Finnish hereditary multiple exostoses family. Mutations in brief no. 197. Online.
Human mutation 1998;12(5):362.
1998: Wa'el El-Rifai; Maarit Sarlomo-Rikala; Leif C Andersson; Markku Miettinen; Sakari Knuutila
DNA copy number changes in gastrointestinal stromal tumors--a distinct genetic entity.
Annales chirurgiae et gynaecologiae 1998;87(4):287-90.
1998: Marcelo L Larramendy; Sanna Siitonen; Ying Zhu; M Hurme; Leena Vilpo; Juhani Vilpo; Sakari Knuutila
Optimized mitogen stimulation induces proliferation of neoplastic B cells in chronic lymphocytic leukemia: significance for cytogenetic analysis.The Tampere Chronic Lympocytic Leukemia group.
Cytogenetics and cell genetics 1998;82(3-4):215-21.
1998: AM Björkqvist; Lauri Tammilehto; Stig Nordling; Markku Nurminen; Sisko Anttila; Karin Mattson; Sakari Knuutila
Comparison of DNA copy number changes in malignant mesothelioma, adenocarcinoma and large-cell anaplastic carcinoma of the lung.
British journal of cancer 1998;77(2):260-9.
1998: Wa'el El-Rifai; Jeffrey C Harper; O W Cummings; Eija-Riitta Hyytinen; Henry F Frierson; Sakari Knuutila; Steven M Powell
Consistent genetic alterations in xenografts of proximal stomach and gastro-esophageal junction adenocarcinomas.
Cancer research 1998;58(1):34-7.
1998: Marcelo L Larramendy; P Majander; Tiina Saarto; Mikko Tenhunen; R Caballín; Inkeri Elomaa; Sakari Knuutila
Radiation therapy for breast cancer and clonal chromosome translocations: a fluorescence in situ hybridization study.
Cancer genetics and cytogenetics 1998;100(1):57-62.
1998: Sakari Knuutila; Gemma Armengol; AM Björkqvist; Wa'el El-Rifai; Marcelo L Larramendy; Outi Monni; J Szymanska
Comparative genomic hybridization study on pooled DNAs from tumors of one clinical-pathological entity.
Cancer genetics and cytogenetics 1998;100(1):25-30.
1997: S Kiuru-Kuhlefelt; Paula Kristo; Tapani Ruutu; Sakari Knuutila; Juha Kere
Evidence for two molecular steps in the pathogenesis of myeloid disorders associated with deletion of chromosome 7 long arm.
Leukemia 1997;11(12):2097-104.
1997: Wa'el El-Rifai; Marcelo L Larramendy; AM Björkqvist; Samuli Hemmer; Sakari Knuutila
Optimization of comparative genomic hybridization using fluorochrome conjugated to dCTP and dUTP nucleotides.
Laboratory investigation; a journal of technical methods and pathology 1997;77(6):699-700.
1997: J Szymanska; Martti Virolainen; Maija Tarkkanen; Tom Wiklund; Sirpa Asko-Seljavaara; Erkki Tukiainen; Inkeri Elomaa; Carl Blomqvist; Sakari Knuutila
Overrepresentation of 1q21-23 and 12q13-21 in lipoma-like liposarcomas but not in benign lipomas: a comparative genomic hybridization study.
Cancer genetics and cytogenetics 1997;99(1):14-8.
1997: Marcelo L Larramendy; Maija Tarkkanen; Carl Blomqvist; Martti Virolainen; Tom Wiklund; Sirpa Asko-Seljavaara; Inkeri Elomaa; Sakari Knuutila
Comparative genomic hybridization of malignant fibrous histiocytoma reveals a novel prognostic marker.
The American journal of pathology 1997;151(4):1153-61.
1997: Arto Kokkola; Outi Monni; Pauli Puolakkainen; Marcelo L Larramendy; M Victorzon; Stig Nordling; Reijo Haapiainen; Eero Kivilaakso; Sakari Knuutila
17q12-21 amplicon, a novel recurrent genetic change in intestinal type of gastric carcinoma: a comparative genomic hybridization study.
Genes, chromosomes & cancer 1997;20(1):38-43.
1997: Ritva Karhu; Sakari Knuutila; Olli Kallioniemi; S Siltonen; Risto Aine; Leena Vilpo; Juhani Vilpo
Frequent loss of the 11q14-24 region in chronic lymphocytic leukemia: a study by comparative genomic hybridization. Tampere CLL Group.
Genes, chromosomes & cancer 1997;19(4):286-90.
1997: Outi Monni; Heikki Joensuu; Kaarle Franssila; Juha Klefstrom; Kari Alitalo; Sakari Knuutila
BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma.
Blood 1997;90(3):1168-74.
1997: Marcelo L Larramendy; J Valle; Maija Tarkkanen; Aarne Kivioja; Erkki O Karaharju; T Salmivalli; Inkeri Elomaa; Sakari Knuutila
No DNA copy number changes in osteochondromas: a comparative genomic hybridization study.
Cancer genetics and cytogenetics 1997;97(1):76-8.
1997: Wa'el El-Rifai; Erkki Elonen; Marcelo L Larramendy; Tapani Ruutu; Sakari Knuutila
Chromosomal breakpoints and changes in DNA copy number in refractory acute myeloid leukemia.
Leukemia 1997;11(7):958-63.
1997: Wa'el El-Rifai; Tapani Ruutu; Kim Vettenranta; Erkki Elonen; UM Saarinen; Liisa Volin; Sakari Knuutila
Follow-up of residual disease using metaphase-FISH in patients with acute lymphoblastic leukemia in remission.
Leukemia 1997;11(5):633-8.
1997: Wa'el El-Rifai; Tapani Ruutu; Erkki Elonen; Liisa Volin; Sakari Knuutila
Prognostic value of metaphase-fluorescence in situ hybridization in follow-up of patients with acute myeloid leukemia in remission.
Blood 1997;89(9):3330-4.
1997: IS Pakkala; Hakan Savli; Sakari Knuutila; L Binderup; Seppo Pakkala
CB1093, a novel vitamin D analog; effects on differentiation and clonal growth on HL-60 and de novo leukemia cells.
Leukemia research 1997;21(4):321-6.
1997: Veli-Matti Wasenius; Antti Jekunen; Outi Monni; Heikki Joensuu; Stefan Aebi; S B Howell; Sakari Knuutila
Comparative genomic hybridization analysis of chromosomal changes occurring during development of acquired resistance to cisplatin in human ovarian carcinoma cells.
Genes, chromosomes & cancer 1997;18(4):286-91.
1997: Marcelo L Larramendy; Maija Tarkkanen; J Valle; Aarne Kivioja; H Ervasti; Erkki O Karaharju; T Salmivalli; Inkeri Elomaa; Sakari Knuutila
Gains, losses, and amplifications of DNA sequences evaluated by comparative genomic hybridization in chondrosarcomas.
The American journal of pathology 1997;150(2):685-91.
1997: Johanna Tapper; Ralf Bützow; Torsten Wahlström; Markku Seppala; Sakari Knuutila
Evidence for divergence of DNA copy number changes in serous, mucinous and endometrioid ovarian carcinomas.
British journal of cancer 1997;75(12):1782-7.
1997: Gemma Armengol; Maija Tarkkanen; Martti Virolainen; Anne Forus; J Valle; Tom Böhling; Sirpa Asko-Seljavaara; Carl Blomqvist; Inkeri Elomaa; Erkki O Karaharju; Aarne Kivioja; Martti A Siimes; Erkki Tukiainen; Maria Rosa Caballín; Ola Myklebost; Sakari Knuutila
Recurrent gains of 1q, 8 and 12 in the Ewing family of tumours by comparative genomic hybridization.
British journal of cancer 1997;75(10):1403-9.
1997: M Wolf; Lauri A Aaltonen; J Szymanska; Maija Tarkkanen; Inkeri Elomaa; Sakari Knuutila
Microsatellite markers as tools for characterization of DNA amplifications evaluated by comparative genomic hybridization.
Cancer genetics and cytogenetics 1997;93(1):33-8.
1997: AM Björkqvist; Lauri Tammilehto; Sisko Anttila; Karin Mattson; Sakari Knuutila
Recurrent DNA copy number changes in 1q, 4q, 6q, 9p, 13q, 14q and 22q detected by comparative genomic hybridization in malignant mesothelioma.
British journal of cancer 1997;75(4):523-7.
1997: Rolf Billström; Bertil Johansson; Bodil Strömbeck; Wa'el El-Rifai; Marcelo L Larramendy; Tor Olofsson; Felix Mitelman; Sakari Knuutila
Clonal CD5-positive B lymphocytes in myelodysplastic syndrome with systemic vasculitis and trisomy 8.
Annals of hematology 1997;74(1):37-40.
1997: Sakari Knuutila
Lineage specificity in haematological neoplasms.
British journal of haematology 1997;96(1):2-11.
1997: M Wolf; Lauri A Aaltonen; J Szymanska; Maija Tarkkanen; Carl Blomqvist; Jeanne-Marie Berner; Ola Myklebost; Sakari Knuutila
Complexity of 12q13-22 amplicon in liposarcoma: microsatellite repeat analysis.
Genes, chromosomes & cancer 1997;18(1):66-70.
1997: Akseli Hemminki; Ian Tomlinson; D Markie; Heikki Järvinen; Pertti Sistonen; AM Björkqvist; Sakari Knuutila; Reijo Salovaara; Walter Bodmer; D Shibata; Albert de La Chapelle; Lauri A Aaltonen
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis.
Nature genetics 1997;15(1):87-90.
1996: Maija Tarkkanen; S Nordling; Tom Böhling; Aarne Kivioja; J Karaharju E Szymanska; Inkeri Elomaa; Sakari Knuutila
Comparison of cytogenetics, interphase cytogenetics, and DNA flow cytometry in bone tumors.
Cytometry 1996;26(3):185-91.
1996: Maija Tarkkanen; Lauri A Aaltonen; Tom Böhling; Aarne Kivioja; Erkki O Karaharju; Inkeri Elomaa; Sakari Knuutila
No evidence of microsatellite instability in bone tumours.
British journal of cancer 1996;74(3):453-5.
1996: Wa'el El-Rifai; Maarit Sarlomo-Rikala; M Miettinen; Sakari Knuutila; Leif C Andersson
DNA copy number losses in chromosome 14: an early change in gastrointestinal stromal tumors.
Cancer research 1996;56(14):3230-3.
1996: P Kivipensas; AM Björkqvist; R Karhu; Katarina Pelin; Kaija Linnainmaa; Lauri Tammilehto; Karin Mattson; Q P Kallioniemi; Sakari Knuutila
Gains and losses of DNA sequences in malignant mesothelioma by comparative genomic hybridization.
Cancer genetics and cytogenetics 1996;89(1):7-13.
1996: Outi Monni; Heikki Joensuu; Kaarle Franssila; Sakari Knuutila
DNA copy number changes in diffuse large B-cell lymphoma--comparative genomic hybridization study.
Blood 1996;87(12):5269-78.
1996: J Szymanska; N Mandahl; F Mertens; Maija Tarkkanen; Erkki O Karaharju; Sakari Knuutila
Ring chromosomes in parosteal osteosarcoma contain sequences from 12q13-15: a combined cytogenetic and comparative genomic hybridization study.
Genes, chromosomes & cancer 1996;16(1):31-4.
1996: A Slunga-Tallberg; Wa'el El-Rifai; M Keinänen; K Ylinen; T Kurki; K Klinger; O Ylikorkala; Marcelo L Larramendy; Sakari Knuutila
Maternal origin of transferrin receptor positive cells in venous blood of pregnant women.
Clinical genetics 1996;49(4):196-9.
1996: J Szymanska; Maija Tarkkanen; Tom Wiklund; Martti Virolainen; Carl Blomqvist; Sirpa Asko-Seljavaara; Erkki Tukiainen; Inkeri Elomaa; Sakari Knuutila
Gains and losses of DNA sequences in liposarcomas evaluated by comparative genomic hybridization.
Genes, chromosomes & cancer 1996;15(2):89-94.
1996: J Szymanska; Maija Tarkkanen; Tom Wiklund; Martti Virolainen; Carl Blomqvist; Sirpa Asko-Seljavaara; Erkki Tukiainen; Inkeri Elomaa; Sakari Knuutila
Cytogenetic study of extraskeletal mesenchymal chondrosarcoma. A case report.
Cancer genetics and cytogenetics 1996;86(2):170-3.
1996: Wa'el El-Rifai; Tapani Ruutu; Kim Vettenranta; S Temtamy; Sakari Knuutila
Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia: a metaphase-FISH study.
British journal of haematology 1996;92(2):365-9.
1996: Wa'el El-Rifai; Marcelo L Larramendy; Tapani Ruutu; Sakari Knuutila
Lymphoid involvement in a patient with acute myeloid leukemia: a direct phenotypic and genotypic study of single cells.
Genes, chromosomes & cancer 1996;15(1):34-7.
1996: Wa'el El-Rifai; Sakari Knuutila
Fluorescent in situ hybridization on archival G-banded slides.
Cytogenetics and cell genetics 1996;73(4):322-4.
1995: H Wu; E Pelkonen; Sakari Knuutila; M Kaartinen
A human follicular lymphoma B cell line hypermutates its functional immunoglobulin genes in vitro.
European journal of immunology 1995;25(12):3263-9.
1995: J Szymanska; Maija Tarkkanen; Tom Wiklund; Martti Virolainen; Carl Blomqvist; Sirpa Asko-Seljavaara; Erkki Tukiainen; Inkeri Elomaa; Sakari Knuutila
A cytogenetic study of malignant fibrous histiocytoma.
Cancer genetics and cytogenetics 1995;85(2):91-6.
1995: Marcelo L Larramendy; Wa'el El-Rifai; U Saarinen; Riitta Alitalo; S Luomahaara; Sakari Knuutila
Myeloid lineage involvement in acute lymphoblastic leukemia: a morphology antibody chromosomes (MAC) study.
Experimental hematology 1995;23(14):1563-7.
1995: P Pylkkänen; A Paetau; Sakari Knuutila
Chromosome 7 in glioblastoma tissue. Parenchymal vs. endothelial cells.
Cancer genetics and cytogenetics 1995;84(1):73-5.
1995: A Slunga-Tallberg; Wa'el El-Rifai; M Keinänen; K Ylinen; T Kurki; K Klinger; O Ylikorkala; Sakari Knuutila
Maternal origin of nucleated erythrocytes in peripheral venous blood of pregnant women.
Human genetics 1995;96(1):53-7.
1995: Maija Tarkkanen; Ritva Karhu; Anne Kallioniemi; I Elomaa; Aarne Kivioja; J Nevalainen; Tom Böhling; Erkki O Karaharju; Eija-Riitta Hyytinen; Sakari Knuutila
Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization.
Cancer research 1995;55(6):1334-8.
1995: Sakari Knuutila; Marcelo L Larramendy; P Elfving; Wa'el El-Rifai; A Miettinen; F Mitelman
Trisomy 7 in non-neoplastic tubular epithelial cells of the kidney.
Human genetics 1995;95(2):149-56.
1995: A Slunga-Tallberg; Sakari Knuutila
Can nucleated erythrocytes found in maternal venous blood be used in the noninvasive prenatal diagnosis of fetal chromosome abnormalities?
European journal of human genetics : EJHG 1995;3(4):264-70.
1995: Julia Catalán; K Autio; M Wessman; Carita Lindholm; Sakari Knuutila; Marja Sorsa; Hannu Norppa
Age-associated micronuclei containing centromeres and the X chromosome in lymphocytes of women.
Cytogenetics and cell genetics 1995;68(1-2):11-6.
1995: Wa'el El-Rifai; Jaakko Leisti; M Kähkönen; A Pietarinen; M R Altherr; Sakari Knuutila
A patient with Wolf-Hirschhorn syndrome originating from translocation t(4;8) (p16.3;q24.3)pat.
Journal of medical genetics 1995;32(1):65-7.
1995: Sakari Knuutila; Marcelo L Larramendy; Tapani Ruutu; T Helander
Involvement of natural killer cells in chronic myeloid leukemia.
Cancer genetics and cytogenetics 1995;79(1):21-4.
1995: P E Kovanen; Sakari Knuutila; Tuomo Timonen
Requirement of CD4+ lymphocytes in IL-2-stimulated NK cell proliferation.
Scandinavian journal of immunology 1995;41(1):70-6.
1995: S C Maric; A Crozat; J Louhimo; Sakari Knuutila; Olli A Jänne
The human S-adenosylmethionine decarboxylase gene: nucleotide sequence of a pseudogene and chromosomal localization of the active gene (AMD1) and the pseudogene (AMD2).
Cytogenetics and cell genetics 1995;70(3-4):195-9.
1994: S J Nylund; Tapani Ruutu; UM Saarinen; Sakari Knuutila
Metaphase fluorescence in situ hybridization (FISH) in the follow-up of 60 patients with haemopoietic malignancies.
British journal of haematology 1994;88(4):778-83.
1994: M Eray; T Tuomikoski; H Wu; T Nordström; Leif C Andersson; Sakari Knuutila; M Kaartinen
Cross-linking of surface IgG induces apoptosis in a bcl-2 expressing human follicular lymphoma line of mature B cell phenotype.
International immunology 1994;6(12):1817-27.
1994: Marcelo L Larramendy; AM Björkqvist; Lauri Tammilehto; M Taavitsainen; Karin Mattson; Sakari Knuutila
Absence of trisomy 7 in nonneoplastic human ascitic and pleural fluid cells. An interphase cytogenetic study.
Cancer genetics and cytogenetics 1994;78(1):78-81.
1994: AM Björkqvist; A Slunga-Tallberg; Maija Wessman; K Ylinen; Sakari Knuutila
Prenatal sex determination by in situ hybridization on fetal nucleated cells in maternal whole venous blood.
Clinical genetics 1994;46(5):352-6.
1994: Wa'el El-Rifai; T Pettersson; Marcelo L Larramendy; Sakari Knuutila
Lineage involvement and karyotype in a patient with myelodysplasia and blood basophilia.
European journal of haematology 1994;53(5):288-92.
1994: AM Björkqvist; Maija Wessman; M Vuorinen; K Ylinen; M Keinänen; A Slunga-Tallberg; Sakari Knuutila
ISH and PCR study with Y-specific probe/primers.
Annals of the New York Academy of Sciences 1994;731():57-66.
1994: A Slunga-Tallberg; Maija Wessman; Harriet von Koskull; K Ylinen; N Gahmberg; Sakari Knuutila
Occurrence of nucleated erythrocytes in peripheral blood of pregnant women.
Annals of the New York Academy of Sciences 1994;731():226-8.
1994: A Slunga-Tallberg; Maija Wessman; K Ylinen; Harriet von Koskull; Sakari Knuutila
Nucleated erythrocytes in enriched and unenriched peripheral venous blood samples from pregnant and nonpregnant women.
Fetal diagnosis and therapy 1994;9(5):291-5.
1994: P Pohjanpelto; S Nordling; Sakari Knuutila
Flow cytometric analysis of the cell cycle in polyamine-depleted cells.
Cytometry 1994;16(4):331-8.
1994: Sakari Knuutila; Lasse Teerenhovi; Marcelo L Larramendy; Erkki Elonen; Kaarle Franssila; S J Nylund; T Timonen; Kirsti Heinonen; Eija H Mahlamäki; R Winqvist
Cell lineage involvement of recurrent chromosomal abnormalities in hematologic neoplasms.
Genes, chromosomes & cancer 1994;10(2):95-102.
1994: Juha Klefstrom; Kaarle Franssila; Päivi Peltomäki; M Kaartinen; Marja-Liisa Solin; Sakari Knuutila
Major and minor breakpoint sites of chromosomal translocation t(14;18) in subtypes of non-Hodgkin's lymphomas.
Leukemia research 1994;18(4):245-50.
1994: S J Nylund; Tapani Ruutu; UM Saarinen; Marcelo L Larramendy; Sakari Knuutila
Detection of minimal residual disease using fluorescence DNA in situ hybridization: a follow-up study in leukemia and lymphoma patients.
Leukemia 1994;8(4):587-94.
1994: H Y Wu; T Tuomikoski; M Eray; P Mattila; Sakari Knuutila; M Kaartinen
Somatic hypermutations in the immunoglobulin genes of two new human lymphoma lines of lymphatic follicle origin.
Scandinavian journal of immunology 1994;39(3):295-300.
1994: Sakari Knuutila; J Klefström; J Szymanska; T Lakkala; Päivi Peltomäki; M Eray; Lasse Teerenhovi; Erkki Elonen; Kaarle Franssila; M Kaartinen
Two novel human B-cell lymphoma lines of lymphatic follicle origin: cytogenetic, molecular genetic and histopathological characterisation.
European journal of haematology 1994;52(2):65-72.
1994: Maija Tarkkanen; Tom Wiklund; Martti Virolainen; Inkeri Elomaa; Sakari Knuutila
Dedifferentiated chondrosarcoma with t(9;22)(q34;q11-12).
Genes, chromosomes & cancer 1994;9(2):136-40.
1994: Sakari Knuutila; S J Nylund; Maija Wessman; Marcelo L Larramendy
Analysis of genotype and phenotype on the same interphase or mitotic cell. A manual of MAC (morphology antibody chromosomes) methodology.
Cancer genetics and cytogenetics 1994;72(1):1-15.
1994: Marcelo L Larramendy; S J Nylund; Maija Wessman; Tapani Ruutu; Sakari Knuutila
Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) study.
British journal of haematology 1994;86(1):203-6.
1994: Sakari Knuutila; P Majander; Tapani Ruutu
8;21 and 15;17 translocations: abnormalities in a single cell lineage in acute myeloid leukemia.
Acta haematologica 1994;92(2):88-90.
1993: Maija Tarkkanen; Erkki O Karaharju; Tom Böhling; J Szymanska; H Heliö; Aarne Kivioja; Inkeri Elomaa; Sakari Knuutila
Chromosome study of 249 patients examined for a bone tumor.
Clinical orthopaedics and related research 1993;(297):117-28.
1993: Sakari Knuutila; Riitta Alitalo; Tapani Ruutu
Power of the MAC (morphology-antibody-chromosomes) method in distinguishing reactive and clonal cells: report of a patient with acute lymphatic leukemia, eosinophilia, and t(5;14).
Genes, chromosomes & cancer 1993;8(4):219-23.
1993: S J Nylund; W Verbeek; Marcelo L Larramendy; Tapani Ruutu; Kirsti Heinonen; H Hallman; Sakari Knuutila
Cell lineage involvement in four patients with myelodysplastic syndrome and t(1;7) or trisomy 8 studied by simultaneous immunophenotyping and fluorescence in situ hybridization.
Cancer genetics and cytogenetics 1993;70(2):120-4.
1993: H Heliö; Aarne Kivioja; Erkki O Karaharju; Inkeri Elomaa; Sakari Knuutila
Malignant fibrous histiocytoma arising in a previous site of fracture and osteomyelitis.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1993;19(5):479-84.
1993: Marcelo L Larramendy; M A Reigosa; Sakari Knuutila
Pig plasma modulates cell cycle kinetics but not the baseline frequency of sister-chromatid exchanges in human lymphocytes.
Mutation research 1993;292(2):165-73.
1993: T Laulajainen; I Julkunen; A Haltia; Sakari Knuutila; Aaro Miettinen; Harry Holthöfer
Establishment and characterization of a rat glomerular endothelial cell line.
Laboratory investigation; a journal of technical methods and pathology 1993;69(2):183-92.
1993: Sakari Knuutila; Marcelo L Larramendy; Tapani Ruutu; A Paetau; Kirsti Heinonen; Eija H Mahlamäki
Analysis of phenotype and genotype of individual cells in neoplasms.
Cancer genetics and cytogenetics 1993;68(2):104-13.
1993: Maija Tarkkanen; A Kaipainen; Erkki O Karaharju; Tom Böhling; J Szymanska; H Heliö; Aarne Kivioja; Inkeri Elomaa; Sakari Knuutila
Cytogenetic study of 249 consecutive patients examined for a bone tumor.
Cancer genetics and cytogenetics 1993;68(1):1-21.
1993: Maija Wessman; S Popp; Tapani Ruutu; L Volin; Thomas Cremer; Sakari Knuutila
Detection of residual host cells after bone marrow transplantation using non-isotopic in situ hybridization and karyotype analysis.
Bone marrow transplantation 1993;11(4):279-84.
1993: Marcelo L Larramendy; M Heiskanen; Maija Wessman; A Ritvanen; Päivi Peltomäki; K Simola; Helena Kääriäinen; Harriet von Koskull; M Kähkönen; Sakari Knuutila
Molecular cytogenetic study of patients with Pallister-Killian syndrome.
Human genetics 1993;91(2):121-7.
1993: Maija Tarkkanen; Tom Böhling; H Heliö; Erkki O Karaharju; A Kaipainen; J Szymanska; Inkeri Elomaa; Sakari Knuutila
A recurrent chondromyxoid fibroma with chromosome aberrations ins(5;2)(q13;p21p25) and 2p deletion: a case report.
Cancer genetics and cytogenetics 1993;65(2):141-6.
1993: Marcelo L Larramendy; S J Nylund; E Armstrong; Sakari Knuutila
Simultaneous detection of high-resolution R-banding and fluorescence in situ hybridization signals after fluorouracil-induced cellular synchronization.
Hereditas 1993;119(1):89-94.
1993: Sakari Knuutila
Molecular cytogenetic applications in leukemias.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():89-101.
1993: Sakari Knuutila; M Lindlöf; P E Kovanen; T Ramqvist; Tapani Ruutu; Leif C Andersson
Philadelphia chromosome as the sole abnormality and p210 bcr-abl chimeric protein expression in an Epstein-Barr virus-transformed B cell line from a patient with chronic myeloid leukemia.
Acta haematologica 1993;90(4):190-4.
1993: Sakari Knuutila; Maija Wessman; S J Nylund; Tapani Ruutu; M Keinänen
[Clinical molecular cytogenetics].
Duodecim; lääketieteellinen aikakauskirja 1993;109(14):1229-37.
1993: Sakari Knuutila; Maija Wessman; K Ylinen
[Identification of fetal chromosome abnormalities and gene defects from maternal blood].
Duodecim; lääketieteellinen aikakauskirja 1993;109(4):276-8.
1992: Maija Wessman; K Ylinen; Sakari Knuutila
Fetal granulocytes in maternal venous blood detected by in situ hybridization.
Prenatal diagnosis 1992;12(12):993-1000.
1992: Marjaana Tiainen; Anton H N Hopman; O Moesker; F Ramaekers; Maija Wessman; A Laasonen; Seppo Pyrhönen; Lauri Tammilehto; Karin Mattson; Sakari Knuutila
Interphase cytogenetics on paraffin sections of malignant pleural mesothelioma. A comparison to conventional karyotyping and flow cytometric studies.
Cancer genetics and cytogenetics 1992;62(2):171-9.
1992: Marjaana Tiainen; Jukka Rautonen; Seppo Pyrhönen; Lauri Tammilehto; Karin Mattson; Sakari Knuutila
Chromosome number correlates with survival in patients with malignant pleural mesothelioma.
Cancer genetics and cytogenetics 1992;62(1):21-4.
1992: Valérie Parlier; Marjaana Tiainen; Photis Beris; P A Miescher; Sakari Knuutila; M Jotterand Bellomo
Trisomy 8 detection in granulomonocytic, erythrocytic and megakaryocytic lineages by chromosomal in situ suppression hybridization in a case of refractory anaemia with ringed sideroblasts complicating the course of paroxysmal nocturnal haemoglobinuria.
British journal of haematology 1992;81(2):296-304.
1992: Seppo Pyrhönen; Marjaana Tiainen; Jukka Rautonen; Lauri Tammilehto; A Laasonen; Karin Mattson; Sakari Knuutila
Comparison of DNA and karyotype ploidy in malignant mesothelioma.
Cancer genetics and cytogenetics 1992;60(1):8-13.
1992: Marjaana Tiainen; Juha Kere; Lauri Tammilehto; Karin Mattson; Sakari Knuutila
Abnormalities of chromosomes 7 and 22 in human malignant pleural mesothelioma: correlation between Southern blot and cytogenetic analyses.
Genes, chromosomes & cancer 1992;4(2):176-82.
1992: Marjaana Tiainen; S Popp; Valérie Parlier; P Emmerich; M J Bellomo; Tapani Ruutu; Thomas Cremer; Sakari Knuutila
Chromosomal in situ suppression hybridization of immunologically classified mitotic cells in hematologic malignancies.
Genes, chromosomes & cancer 1992;4(2):135-40.
1992: Sakari Knuutila; Marcelo L Larramendy
Sister chromatid differentiation and chromosomal in situ suppression hybridization: a combined methodology for analyzing cell proliferation and SCEs in individual chromosomes.
Cytogenetics and cell genetics 1992;61(2):99-102.
1992: Lauri Tammilehto; Timo Tuomi; Marjaana Tiainen; Jukka Rautonen; Sakari Knuutila; Seppo Pyrhönen; Karin Mattson
Malignant mesothelioma: clinical characteristics, asbestos mineralogy and chromosomal abnormalities of 41 patients.
European journal of cancer (Oxford, England : 1990) 1992;28A(8-9):1373-9.
1991: H Hirvonen; Veijo Hukkanen; Toivo T Salmi; Tomi Mäkelä; Tarja-Terttu Pelliniemi; Sakari Knuutila; Riitta Alitalo
Expression of L-myc and N-myc proto-oncogenes in human leukemias and leukemia cell lines.
Blood 1991;78(11):3012-20.
1991: A P Losada; Maija Wessman; Marjaana Tiainen; Anton H N Hopman; Huntington F Willard; Francesc Solé; Maria Rosa Caballín; S Woessner; Sakari Knuutila
Trisomy 12 in chronic lymphocytic leukemia: an interphase cytogenetic study.
Blood 1991;78(3):775-9.
1991: Marcelo L Larramendy; Sakari Knuutila
Increased frequency of micronuclei in B and T8 lymphocytes from smokers.
Mutation research 1991;259(2):189-95.
1991: Tapani Ruutu; P Peltomäki; L Volin; M Lindlöf; Sakari Knuutila
Karyotype and BCR studies after bone marrow transplantation for chronic myeloid leukaemia.
Bone marrow transplantation 1991;7 Suppl 2():20.
1990: Seppo Pakkala; Sakari Knuutila; P Helminen; Tapani Ruutu; UM Saarinen; Leena Peltonen
DNA-fingerprint changes compared to karyotypes in acute leukemia.
Leukemia 1990;4(12):866-70.
1990: T Lakkala; A Laasonen; Kaarle Franssila; Lasse Teerenhovi; Sakari Knuutila
Comparison of DNA and karyotype aneuploidy in malignant lymphomas.
American journal of clinical pathology 1990;94(5):600-5.
1990: P E Kovanen; Kaarle Franssila; Päivi Peltomäki; Sakari Knuutila
Effect of a low-molecular-weight B cell growth factor on the proliferation of normal and neoplastic lymphocytes in lymphomas.
Cancer genetics and cytogenetics 1990;48(1):109-18.
1990: Marcelo L Larramendy; Päivi Peltomäki; E Salonen; Sakari Knuutila
Chromosomal abnormality limited to T4 lymphocytes in a patient with T-cell chronic lymphocytic leukaemia.
European journal of haematology 1990;45(1):52-9.
1990: Marcelo L Larramendy; Sakari Knuutila
Immunophenotype and sister chromatid differentiation: a combined methodology for analyzing cell proliferation in unfractionated lymphocyte cultures.
Experimental cell research 1990;188(2):209-13.
1990: J Klefström; M Kaartinen; Päivi Peltomäki; Marja-Liisa Solin; Kaarle Franssila; Sakari Knuutila
[The use of polymerase chain reaction in the diagnosis of non-Hodgkin's lymphoma].
Duodecim; lääketieteellinen aikakauskirja 1990;106(23-24):1645-53.
1989: Marjaana Tiainen; Lauri Tammilehto; Jukka Rautonen; Timo Tuomi; Karin Mattson; Sakari Knuutila
Chromosomal abnormalities and their correlations with asbestos exposure and survival in patients with mesothelioma.
British journal of cancer 1989;60(4):618-26.
1989: C Lindholm; Kaarle Franssila; Lasse Teerenhovi; Erkki Elonen; Päivi Peltomäki; J Rapola; Tapani Ruutu; UM Saarinen; Sakari Knuutila
Characterization of neoplastic and reactive cells in T-cell lymphomas with cytogenetic, surface marker, and DNA methods.
British journal of haematology 1989;73(1):68-75.
1989: Sakari Knuutila; Lasse Teerenhovi
Immunophenotyping of aneuploid cells.
Cancer genetics and cytogenetics 1989;41(1):1-17.
1989: Maija Wessman; Tapani Ruutu; L Volin; Sakari Knuutila
In situ hybridization using a Y-specific probe--a sensitive method for distinguishing residual male recipient cells from female donor cells in bone marrow transplantation.
Bone marrow transplantation 1989;4(3):283-6.
1989: E Juvonen; S Partanen; Sakari Knuutila; Tapani Ruutu
Colony formation by megakaryocyte progenitors in myelodysplatic syndromes.
European journal of haematology 1989;42(4):389-95.
1988: Lasse Teerenhovi; C Lindholm; A Pakkala; Kaarle Franssila; H Stein; Sakari Knuutila
Unique display of a pathologic karyotype in Hodgkin's disease by Reed-Sternberg cells.
Cancer genetics and cytogenetics 1988;34(2):305-11.
1988: K Heinonen; J Rautonen; M A Siimes; Sakari Knuutila
Cytogenetic study of 105 children with acute lymphoblastic leukemia.
European journal of haematology 1988;41(3):237-42.
1988: Marjaana Tiainen; Lauri Tammilehto; Karin Mattson; Sakari Knuutila
Nonrandom chromosomal abnormalities in malignant pleural mesothelioma.
Cancer genetics and cytogenetics 1988;33(2):251-74.
1988: Päivi Peltomäki; N O Bianchi; Sakari Knuutila; Lasse Teerenhovi; Erkki Elonen; R Leskinen; Albert de La Chapelle
Immunoglobulin kappa and lambda light chain dual genotype rearrangement in a patient with kappa-secreting B-CLL.
European journal of cancer & clinical oncology 1988;24(7):1233-8.
1988: Kaarle Franssila; C Lindholm; Lasse Teerenhovi; Sakari Knuutila
A method combining morphological, immunocytochemical and chromosomal examinations of the same cell in the study of lymphoproliferative diseases.
European journal of haematology 1988;40(4):332-8.
1988: Juha Kere; Sakari Knuutila; Tapani Ruutu; R Leskinen; Albert de La Chapelle
Monocytic involvement by monosomy 7 preceded acute myelomonocytic leukemia in a patient with myelodysplastic syndrome.
Leukemia 1988;2(2):69-73.
1988: Liisa Volin; Tapani Ruutu; Sakari Knuutila; R Tenhunen
Heme arginate treatment for myelodysplastic syndromes.
Leukemia research 1988;12(5):423-31.
1988: P Pohjanpelto; Erkki Hölttä; A Maiche; Sakari Knuutila
Effect of difluoromethylornithine on chromosomes in living organisms and in tissue culture cells.
Hereditas 1988;108(1):85-91.
1987: Sakari Knuutila; P E Kovanen
Relative proportions of mitotic T and B cells in PHA-stimulated lymphocyte cultures.
Cancer genetics and cytogenetics 1987;29(1):151-4.
1987: L Keskiaho; Sakari Knuutila; Helena Pihko; A Nuutila; U Kaski; M Koivikko; Albert de La Chapelle
The inheritance of fragile sites: apparent absence of fra(2)(q13) in the parents of three unrelated probands.
Journal of medical genetics 1987;24(11):678-83.
1987: Kirsi Autio; Erkki Elonen; Lasse Teerenhovi; Sakari Knuutila
Cytogenetic and immunologic characterization of mitotic cells in chronic lymphocytic leukaemia.
European journal of haematology 1987;39(4):289-98.
1987: Lasse Teerenhovi; R Lintula; Tapani Ruutu; Sakari Knuutila
Correlation between bone marrow karyotype and the occurrence of erythroblast micronuclei and nuclear budding in patients with myelodysplastic syndromes.
European journal of haematology 1987;39(3):237-40.
1987: T Lakkala-Paranko; Kaarle Franssila; K Lappalainen; R Leskinen; Sakari Knuutila; Albert de La Chapelle; C D Bloomfield
Chromosome abnormalities in peripheral T-cell lymphoma.
British journal of haematology 1987;66(4):451-60.
1987: P Peltomäki; Sakari Knuutila; A Ritvanen; Ilkka Kaitila; A de la Chapelle
Pallister-Killian syndrome: cytogenetic and molecular studies.
Clinical genetics 1987;31(6):399-405.
1987: M Keinänen; Sakari Knuutila; C D Bloomfield; Erkki Elonen; Albert de La Chapelle
Bone marrow cytogenetics: the lineage of dividing cells changes during the first few hours in culture.
Leukemia 1987;1(1):32-7.
1986: E Juvonen; S Partanen; Sakari Knuutila; Tapani Ruutu
Megakaryocyte colony formation by bone marrow progenitors in myelodysplastic syndromes.
British journal of haematology 1986;63(2):331-4.
1986: M Keinänen; Sakari Knuutila; C D Bloomfield; Erkki Elonen; Albert de La Chapelle
The proportion of mitoses in different cell lineages changes during short-term culture of normal human bone marrow.
Blood 1986;67(5):1240-3.
1986: Sakari Knuutila; Erkki Elonen; Lasse Teerenhovi; L Rossi; R Leskinen; C D Bloomfield; Albert de La Chapelle
Trisomy 12 in B cells of patients with B-cell chronic lymphocytic leukemia.
The New England journal of medicine 1986;314(14):865-9.
1985: Kari Alitalo; K Saksela; R Winqvist; R Alitalo; Jorma Keski-Oja; M Laiho; M Ilvonen; Sakari Knuutila; Albert de La Chapelle
Acute myelogenous leukaemia with c-myc amplification and double minute chromosomes.
Lancet 1985;2(8463):1035-9.
1985: P Pohjanpelto; Erkki Hölttä; O A Jänne; Sakari Knuutila; K Alitalo
Amplification of ornithine decarboxylase gene in response to polyamine deprivation in Chinese hamster ovary cells.
The Journal of biological chemistry 1985;260(14):8532-7.
1984: Tapani Ruutu; S Partanen; R Lintula; Lasse Teerenhovi; Sakari Knuutila
Erythroid and granulocyte-macrophage colony formation in myelodysplastic syndromes.
Scandinavian journal of haematology 1984;32(4):395-402.
1980: U Gripenberg; K Hongell; Sakari Knuutila; M Kähkönen; J Leisti
A chromosome survey of 1062 mentally retarded patients. Evaluation of a long-term study at the Rinnekoti institution, Finland.
Hereditas 1980;92(2):223-8.