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Joshua Ko

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K K Auyeung; P C Law; P K Woo; Joshua K S Ko
Astragalus saponins modulate cell invasiveness and angiogenesis in human gastric adenocarcinoma cells.
Helen P S Wong; Judy W C Ho; Marcel Wing Leung Koo; Le Yu; William Ka-Kei Wu; Emily K Y Lam; Emily K K Tai; Joshua K S Ko; Vivian Shin; Kent-Man Chu; Chi-Hin Cho
Effects of adrenaline in human colon adenocarcinoma HT-29 cells.
Joshua K S Ko; Chi-Hin Cho
Adaptive cytoprotection and the brain-gut axis.

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All Publications

2012: K K Auyeung; P C Law; P K Woo; Joshua K S Ko
Astragalus saponins modulate cell invasiveness and angiogenesis in human gastric adenocarcinoma cells.
Journal of ethnopharmacology 2012;141(2):635-41.
2011: Helen P S Wong; Judy W C Ho; Marcel Wing Leung Koo; Le Yu; William Ka-Kei Wu; Emily K Y Lam; Emily K K Tai; Joshua K S Ko; Vivian Shin; Kent-Man Chu; Chi-Hin Cho
Effects of adrenaline in human colon adenocarcinoma HT-29 cells.
Life sciences 2011;88(25-26):1108-12.
2011: Joshua K S Ko; Chi-Hin Cho
Adaptive cytoprotection and the brain-gut axis.
Digestion 2011;83 Suppl 1():19-24.
2010: Joshua K S Ko; Catherine C Leung
Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats.
Journal of gastroenterology and hepatology 2010;25(12):1861-8.
2010: Kathy Ka-Wai Auyeung; Nga-Lai Mok; Ching-Man Wong; Chi-Hin Cho; Joshua K S Ko
Astragalus saponins modulate mTOR and ERK signaling to promote apoptosis through the extrinsic pathway in HT-29 colon cancer cells.
International journal of molecular medicine 2010;26(3):341-9.
2009: Kathy K W Auyeung; Chi-Hin Cho; Joshua K S Ko
A novel anticancer effect of Astragalus saponins: Transcriptional activation of NSAID-activated gene.
International journal of cancer. Journal international du cancer 2009;125(5):1082-91.
2009: Kathy Ka-wai Auyeung; Pui-ching Law; Joshua K S Ko
Astragalus saponins induce apoptosis via an ERK-independent NF-kappaB signaling pathway in the human hepatocellular HepG2 cell line.
International journal of molecular medicine 2009;23(2):189-96.
2008: Kathy Ka-Wai Au-Yeung; Po-Ling Liu; Cecilia Chan; Wing-Yee Wu; Susanna Sau-Tuen Lee; Joshua K S Ko
Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma.
Cancer investigation 2008;26(7):708-17.
2007: Mandy M Y Tin; Chi-Hin Cho; Kelvin Chan; Anthony E James; Joshua K S Ko
Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft.
Carcinogenesis 2007;28(6):1347-55.
2007: Joshua K S Ko; Wan C Leung; Wai K Ho; Pauline Chiu
Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene.
European journal of pharmacology 2007;559(1):1-13.
2005: Joshua K S Ko; Flora-Ying-Lee Lam; Andrew-Pok-Lap Cheung
Amelioration of experimental colitis by Astragalus membranaceus through anti-oxidation and inhibition of adhesion molecule synthesis.
World journal of gastroenterology : WJG 2005;11(37):5787-94.
2005: Joshua K S Ko; Chi-Hin Cho
The diverse actions of nicotine and different extracted fractions from tobacco smoke against hapten-induced colitis in rats.
Toxicological sciences : an official journal of the Society of Toxicology 2005;87(1):285-95.
2004: Joshua K S Ko; Chi-Hin Cho; Shiu Kum Lam
Adaptive cytoprotection through modulation of nitric oxide in ethanol-evoked gastritis.
World journal of gastroenterology : WJG 2004;10(17):2503-8.
2002: Ho H Luk; Joshua K S Ko; Hon S Fung; Chi-Hin Cho
Delineation of the protective action of zinc sulfate on ulcerative colitis in rats.
European journal of pharmacology 2002;443(1-3):197-204.
2001: X Guo; Edgar S L Liu; Joshua K S Ko; Benjamin Chun-Yu Wong; Y Ye; S Lam; C Cho
Protective role of cyclooxygenase inhibitors in the adverse action of passive cigarette smoking on the initiation of experimental colitis in rats.
European journal of pharmacology 2001;411(1-2):193-203.
2001: X Guo; Joshua K S Ko; Qi-Bing Mei; Chi-Hin Cho
Aggravating effect of cigarette smoke exposure on experimental colitis is associated with leukotriene B(4) and reactive oxygen metabolites.
Digestion 2001;63(3):180-7.
2001: Joshua K S Ko; N F Sham; X Guo; Chi-Hin Cho
Beneficial intervention of experimental colitis by passive cigarette smoking through the modulation of cytokines in rats.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2001;49(1):21-9.
1999: X Guo; Wei-Ping Wang; Joshua K S Ko; Chi-Hin Cho
Involvement of neutrophils and free radicals in the potentiating effects of passive cigarette smoking on inflammatory bowel disease in rats.
Gastroenterology 1999;117(4):884-92.
1999: Joshua K S Ko; Chi-Hin Cho
Co-regulation of mucosal nitric oxide and prostaglandin in gastric adaptive cytoprotection.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48(9):471-8.
1998: Joshua K S Ko; Chi-Hin Cho
Histological study of mechanisms of adaptive cytoprotection on ethanol-induced mucosal damage in rat stomachs.
Digestive diseases and sciences 1998;43(6):1248-57.
1998: Joshua K S Ko; J J Ma; JY Chow; L Ma; Chi-Hin Cho
The correlation of the weakening effect on gastric mucosal integrity by 5-HT with neutrophil activation.
Free radical biology & medicine 1998;24(6):1007-14.
1997: Joshua K S Ko; Chi Kong Ching; JY Chow; S T Zhang; Shiu Kum Lam; Chi-Hin Cho
The vascular and glandular organoprotective properties of metronidazole in the rodent stomach.
Alimentary pharmacology & therapeutics 1997;11(4):811-9.
1996: Joshua K S Ko; Chi-Hin Cho
The antilesion actions of anticholinergic agents on ethanol-induced injury in rat stomachs: the importance of gastric vascular integrity and tonicity.
Journal of autonomic pharmacology 1996;16(3):117-24.
1996: Joshua K S Ko; Chi-Hin Cho
Adaptive gastric mucosal cytoprotection in rats: different modes of action by three mild irritants.
Digestion 1996;57(1):54-9.
1995: Joshua K S Ko; Chi-Hin Cho; Shiu Kum Lam; C K Ching
The importance of gastric emptying and mucosal folds in the adaptive cytoprotection of mild irritants in rats.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44(12):518-22.
1995: Y S Chan; Joshua K S Ko; Chi-Hin Cho
Role of dorsal motor nucleus of vagus in gastric function and mucosal damage induced by ethanol in rats.
Digestive diseases and sciences 1995;40(11):2312-6.
1995: Joshua K S Ko; Chi-Hin Cho
The mechanistic pathway of gastric adaptive cytoprotection: a study on different components of the autonomic nervous system.
Journal of autonomic pharmacology 1995;15(3):205-14.
1995: Joshua K S Ko; Chi-Hin Cho
The role of non-protein sulfhydryl compounds in gastric adaptive cytoprotection against ethanol-induced mucosal damage in rats.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44(6):242-4.
1995: Joshua K S Ko; Chi-Hin Cho; Shiu Kum Lam; Marcel Wing Leung Koo; C K Ching
Contributions of physical and chemical properties of mild irritants to gastric cytoprotection in rats.
Life sciences 1995;57(1):PL13-8.
1995: Joshua K S Ko; Chi-Hin Cho
Endogenous mediators in adaptive cytoprotection against ethanol-induced gastric gland damage in rabbits.
Life sciences 1995;56(1):PL1-5.
1994: Chi-Hin Cho; Marcel Wing Leung Koo; Joshua K S Ko
Modulatory role of 5-HT3 receptors in gastric function and ethanol-induced mucosal damage in rat stomachs.
Pharmacology 1994;49(3):137-43.
1994: Joshua K S Ko; Chi-Hin Cho; C W Ogle
A correlative study on the mechanism of adaptive cytoprotection against ethanol-induced gastric lesion formation in rats.
Journal of gastroenterology and hepatology 1994;9(5):492-500.
1994: Joshua K S Ko; Chi-Hin Cho; C W Ogle
The vagus nerve and its non-cholinergic mechanism in the modulation of ethanol-induced gastric mucosal damage in rats.
The Journal of pharmacy and pharmacology 1994;46(1):29-33.
1994: Chi-Hin Cho; BW Chen; C S Ho; Joshua K S Ko; Shiu Kum Lam
Assessment of hemodynamic changes in rat stomachs by laser Doppler velocimetry and reflectance spectrophotometry. Effects of ethanol and prostaglandin E2 under ischemic and congestive conditions.
Digestion 1994;55(6):389-94.
1994: Chi-Hin Cho; Joshua K S Ko; X L Tang
The differential mechanisms of mild irritants on adaptive cytoprotection.
Journal of gastroenterology and hepatology 1994;9 Suppl 1():S24-8.