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Jun'ichi Kobayashi

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TOP 3
Rei Momose; Naonobu Tanaka; Jane Fromont; Jun'ichi Kobayashi
Hyrtimomines A-C, New Heteroaromatic Alkaloids from a Sponge Hyrtios sp.
Yohei Takahashi; Sunao Yamamoto; Takaaki KUBOTA; Jun'ichi Kobayashi
Inhibitory effects of metachromins L-Q and its related analogs against receptor tyrosine kinases EGFR and HER2.
Takaaki KUBOTA; Azusa Takahashi-Nakaguchi; Jane Fromont; Tohru Gonoi; Yuichiro Ishiguro; Jun'ichi Kobayashi
Manzamenones L-N, new dimeric fatty-acid derivatives from an Okinawan marine sponge Plakortis sp.

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2013: Rei Momose; Naonobu Tanaka; Jane Fromont; Jun'ichi Kobayashi
Hyrtimomines A-C, New Heteroaromatic Alkaloids from a Sponge Hyrtios sp.
Organic letters 2013;15(8):2010-3.
2013: Yohei Takahashi; Sunao Yamamoto; Takaaki KUBOTA; Jun'ichi Kobayashi
Inhibitory effects of metachromins L-Q and its related analogs against receptor tyrosine kinases EGFR and HER2.
Bioorganic & medicinal chemistry letters 2013;23(1):117-8.
2013: Takaaki KUBOTA; Azusa Takahashi-Nakaguchi; Jane Fromont; Tohru Gonoi; Yuichiro Ishiguro; Jun'ichi Kobayashi
Manzamenones L-N, new dimeric fatty-acid derivatives from an Okinawan marine sponge Plakortis sp.
Bioorganic & medicinal chemistry letters 2013;23(1):244-7.
2012: Naonobu Tanaka; Akihito Yamano; Jane Fromont; Haruaki Ishiyama; Takaaki KUBOTA; Motoo Shiro; Shohei Suto; Jun'ichi Kobayashi
Halichonadins K and L, new dimeric sesquiterpenoids from a sponge Halichondria sp.
Organic letters 2012;14(13):3498-501.
2012: Takaaki KUBOTA; Hiroya Mukai; Shinya Watase; Jane Fromont; Jun'ichi Kobayashi
Tyrokeradines C-F, new bromotyrosine alkaloids from the Verongid sponges.
Chemical & pharmaceutical bulletin 2012;60(12):1599-601.
2011: Naonobu Tanaka; Motoo Shiro; Shuhei Abe; Kimiko Hasegawa; Jun'ichi Kobayashi
Biyoulactones A-C, new pentacyclic meroterpenoids from Hypericum chinense.
Organic letters 2011;13(20):5488-91.
2011: Naonobu Tanaka; Tohru Gonoi; Takuji Mamemura; Azusa Shibazaki; Jun'ichi Kobayashi
Yojironins E-I, prenylated acylphloroglucinols from Hypericum yojiroanum.
Bioorganic & medicinal chemistry letters 2011;21(18):5393-7.
2011: Teppei Suzuki; Takaaki KUBOTA; Jun'ichi Kobayashi
Eudistomidins H-K, new β-carboline alkaloids from the Okinawan marine tunicate Eudistoma glaucus.
Bioorganic & medicinal chemistry letters 2011;21(14):4220-3.
2011: Yohei Takahashi; Jane Fromont; Tohru Gonoi; Takaaki KUBOTA; Azusa Shibazaki; Jun'ichi Kobayashi
Nakijinamines C-E, new heteroaromatic alkaloids from the sponge Suberites species.
Organic letters 2011;13(12):3016-9.
2011: Yohei Takahashi; Yoshiro Iinuma; Takaaki KUBOTA; Masashi Tsuda; Mitsuhiro Sekiguchi; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi
Hyrtioseragamines A and B, new alkaloids from the sponge Hyrtios species.
Organic letters 2011;13(4):628-31.
2011: Naonobu Tanaka; Shohei Suto; Jun'ichi Kobayashi
Veramadines A and B, New Steroidal Alkaloids from Veratrum maackii var. japonicum.
Chemical & pharmaceutical bulletin 2011;59(7):909-12.
2011: Ken'ichi Kura; Takaaki KUBOTA; Jane Fromont; Jun'ichi Kobayashi
Pyrinodemins E and F, new 3-alkylpyridine alkaloids from sponge Amphimedon sp.
Bioorganic & medicinal chemistry letters 2011;21(1):267-70.
2010: Naonobu Tanaka; Mio Otani; Yoshiki Kashiwada; Yoshihisa Takaishi; Azusa Shibazaki; Tohru Gonoi; Motoo Shiro; Jun'ichi Kobayashi
Petiolins J-M, prenylated acylphloroglucinols from Hypericum pseudopetiolatum var. kiusianum.
Bioorganic & medicinal chemistry letters 2010;20(15):4451-5.
2010: Yuji Kon; Takaaki KUBOTA; Azusa Shibazaki; Tohru Gonoi; Jun'ichi Kobayashi
Ceratinadins A-C, new bromotyrosine alkaloids from an Okinawan marine sponge Pseudoceratina sp.
Bioorganic & medicinal chemistry letters 2010;20(15):4569-72.
2010: Yohei Takahashi; Haruaki Ishiyama; Takaaki KUBOTA; Jun'ichi Kobayashi
Eudistomidin G, a new beta-carboline alkaloid from the Okinawan marine tunicate Eudistoma glaucus and structure revision of eudistomidin B.
Bioorganic & medicinal chemistry letters 2010;20(14):4100-3.
2010: Yohei Takahashi; Masahiro Ushio; Takaaki KUBOTA; Sunao Yamamoto; Jane Fromont; Jun'ichi Kobayashi
Nakijiquinones J--R, sesquiterpenoid quinones with an amine residue from okinawan marine sponges.
Journal of natural products 2010;73(3):467-71.
2009: Masahiro Hangyou; Haruaki Ishiyama; Yohei Takahashi; Jun'ichi Kobayashi
Total synthesis of amphidinolide Q.
Organic letters 2009;11(21):5046-9.
2009: Naonobu Tanaka; Takaaki KUBOTA; Yoshiki Kashiwada; Yoshihisa Takaishi; Jun'ichi Kobayashi
Petiolins F-I, benzophenone rhamnosides from Hypericum pseudopetiolatum var. kiusianum.
Chemical & pharmaceutical bulletin 2009;57(10):1171-3.
2009: Kan'ichiro Ishiuchi; Shihomi Kodama; Takaaki KUBOTA; Shigeki Hayashi; Toshiro Shibata; Jun'ichi Kobayashi
Lannotinidines H-J, new Lycopodium alkaloids from Lycopodium annotinum.
Chemical & pharmaceutical bulletin 2009;57(8):877-81.
2009: Jun'ichi Kobayashi; Takaaki KUBOTA
The Daphniphyllum alkaloids.
Natural product reports 2009;26(7):936-62.
2009: Haruaki Ishiyama; Hikaru Nakajima; Hiroyasu Nakata; Jun'ichi Kobayashi
Synthesis of hybrid analogues of caffeine and eudistomin D and its affinity for adenosine receptors.
Bioorganic & medicinal chemistry 2009;17(13):4280-4.
2009: Takaaki KUBOTA; Hiroko Yahata; Sunao Yamamoto; Shigeki Hayashi; Toshiro Shibata; Jun'ichi Kobayashi
Serratezomines D and E, new Lycopodium alkaloids from Lycopodium serratum var. serratum.
Bioorganic & medicinal chemistry letters 2009;19(13):3577-80.
2009: Takaaki KUBOTA; Teppei Suzuki; Kan'ichiro Ishiuchi; Taiga Kuhara; Jun'ichi Kobayashi
Daphnezomines T--V, alkaloids from Daphniphyllum humile.
Chemical & pharmaceutical bulletin 2009;57(5):504-7.
2009: Atsushi Araki; Takaaki KUBOTA; Kazuki Aoyama; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi
Nagelamides Q and R, novel dimeric bromopyrrole alkaloids from sponges Agelas sp.
Organic letters 2009;11(8):1785-8.
2009: Tetsuro Yasuda; Atsushi Araki; Takaaki KUBOTA; Junji Ito; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi
Bromopyrrole alkaloids from marine sponges of the genus Agelas.
Journal of natural products 2009;72(3):488-91.
2009: Yohei Takahashi; Takaaki KUBOTA; Jun'ichi Kobayashi
Nakijiquinones E and F, new dimeric sesquiterpenoid quinones from marine sponge.
Bioorganic & medicinal chemistry 2009;17(6):2185-8.
2009: Hiroya Mukai; Takaaki KUBOTA; Kazuki Aoyama; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi
Tyrokeradines A and B, new bromotyrosine alkaloids with an imidazolyl-quinolinone moiety from a verongid sponge.
Bioorganic & medicinal chemistry letters 2009;19(5):1337-9.
2009: Hiroko Yahata; Takaaki KUBOTA; Jun'ichi Kobayashi
Calyciphyllines N-P, alkaloids from Daphniphyllum calycinum.
Journal of natural products 2009;72(1):148-51.
2009: Yohei Takahashi; Takaaki KUBOTA; Jane Fromont; Jun'ichi Kobayashi
Zamamidines A and B, new manzamine alkaloids from the sponge Amphimedon species.
Organic letters 2009;11(1):21-4.
2008: Yusuke Hirasawa; Tomoyuki Tanaka; Jun'ichi Kobayashi; Nobuo Kawahara; Yukihiro Goda; Hiroshi Morita
Malycorins A--C, New lycopodium alkaloids from Lycopodium phlegmaria.
Chemical & pharmaceutical bulletin 2008;56(10):1473-6.
2008: Yohei Takahashi; Takaaki KUBOTA; Eri Fukushi; Jun Kawabata; Jun'ichi Kobayashi
Absolute stereochemistry of amphidinolide Q.
Organic letters 2008;10(17):3709-11.
2008: Yohei Takahashi; Takaaki KUBOTA; Junji Ito; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi
Nakijiquinones G-I, new sesquiterpenoid quinones from marine sponge.
Bioorganic & medicinal chemistry 2008;16(16):7561-4.
2008: Haruaki Ishiyama; Shingo Kozawa; Kazuki Aoyama; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi
Halichonadin F and the Cu(I) complex of halichonadin C from the sponge Halichondria sp.
Journal of natural products 2008;71(7):1301-3.
2008: Yusuke Hirasawa; Eri Kato; Jun'ichi Kobayashi; Nobuo Kawahara; Yukihiro Goda; Motoo Shiro; Hiroshi Morita
Lycoparins A-C, new alkaloids from Lycopodium casuarinoides inhibiting acetylcholinesterase.
Bioorganic & medicinal chemistry 2008;16(11):6167-71.
2008: Naonobu Tanaka; Takaaki KUBOTA; Haruaki Ishiyama; Atsushi Araki; Yoshiki Kashiwada; Yoshihisa Takaishi; Yuzuru Mikami; Jun'ichi Kobayashi
Petiolins A-C, phloroglucinol derivatives from Hypericum pseudopetiolatum var. kiusianum.
Bioorganic & medicinal chemistry 2008;16(10):5619-23.
2008: Haruaki Ishiyama; Taro Okubo; Tetsuro Yasuda; Yohei Takahashi; Kazuo Iguchi; Jun'ichi Kobayashi
Brianodins A-D, briarane-type diterpenoids from soft coral Pachyclavularia sp.
Journal of natural products 2008;71(4):633-6.
2008: Haruaki Ishiyama; Kengo Ohshita; Tetsuro Abe; Hiroyasu Nakata; Jun'ichi Kobayashi
Synthesis of eudistomin D analogues and its effects on adenosine receptors.
Bioorganic & medicinal chemistry 2008;16(7):3825-30.
2008: Shingo Kozawa; Haruaki Ishiyama; Jane Fromont; Jun'ichi Kobayashi
Halichonadin E, a dimeric sesquiterpenoid from the sponge Halichondria sp.
Journal of natural products 2008;71(3):445-7.
2008: Keiko Oguchi; Masashi Tsuda; Rie Iwamoto; Yumiko Okamoto; Jun'ichi Kobayashi; Eri Fukushi; Jun Kawabata; Tomoko Ozawa; Atsunori Masuda; Yoshiaki Kitaya; Kenji Omasa
Iriomoteolide-3a, a cytotoxic 15-membered macrolide from a marine dinoflagellate amphidinium species.
The Journal of organic chemistry 2008;73(4):1567-70.
2007: Koichiro Koyama; Yusuke Hirasawa; Jun'ichi Kobayashi; Hiroshi Morita
Cryptadines A and B, novel C27N3-type pentacyclic alkaloids from Lycopodium cryptomerinum.
Bioorganic & medicinal chemistry 2007;15(24):7803-8.
2007: Yohei Takahashi; Mika Yamada; Takaaki KUBOTA; Jane Fromont; Jun'ichi Kobayashi
Metachromins R--T, new sesquiterpenoids from marine sponge Spongia sp.
Chemical & pharmaceutical bulletin 2007;55(12):1731-3.
2007: Keiko Oguchi; Masashi Tsuda; Rie Iwamoto; Yumiko Okamoto; Taeko Endo; Jun'ichi Kobayashi; Tomoko Ozawa; Atsunori Masuda
Amphidinolides B6 and B7, cytotoxic macrolides from a symbiotic dinoflagellate Amphidinium species.
Journal of natural products 2007;70(10):1676-9.
2007: Kengo Ohshita; Haruaki Ishiyama; Yohei Takahashi; Junji Ito; Yuzuru Mikami; Jun'ichi Kobayashi
Synthesis of penaresidin derivatives and its biological activity.
Bioorganic & medicinal chemistry 2007;15(14):4910-6.
2007: Atsushi Araki; Masashi Tsuda; Takaaki KUBOTA; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi
Nagelamide J, a novel dimeric bromopyrrole alkaloid from a sponge Agelas species.
Organic letters 2007;9(12):2369-71.
2007: Yohei Takahashi; Takaaki KUBOTA; Jun'ichi Kobayashi
Amphidinolactone B, a new 26-membered macrolide from dinoflagellate Amphidinium sp.
The Journal of antibiotics 2007;60(6):376-9.
2007: Kengo Ohshita; Haruaki Ishiyama; Koshi Oyanagi; Hiroyasu Nakata; Jun'ichi Kobayashi
Synthesis of hybrid molecules of caffeine and eudistomin D and its effects on adenosine receptors.
Bioorganic & medicinal chemistry 2007;15(9):3235-40.
2007: Shizuka Saito; Takaaki KUBOTA; Eri Fukushi; Jun Kawabata; Huiping Zhang; Jun'ichi Kobayashi
Calyciphylline D, a novel alkaloid with an unprecedented fused-pentacyclic skeleton from Daphniphyllum calycinum.
Organic letters 2007;9(7):1207-9.
2007: Taeko Endo; Masashi Tsuda; Jane Fromont; Jun'ichi Kobayashi
Hyrtinadine A, a bis-indole alkaloid from a marine sponge.
Journal of natural products 2007;70(3):423-4.
2007: Jun'ichi Kobayashi; Takaaki KUBOTA
Bioactive macrolides and polyketides from marine dinoflagellates of the genus Amphidinium.
Journal of natural products 2007;70(3):451-60.
2007: Chee Yan Choo; Yusuke Hirasawa; Chiaki Karimata; Koichiro Koyama; Mitsuhiro Sekiguchi; Jun'ichi Kobayashi; Hiroshi Morita
Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase.
Bioorganic & medicinal chemistry 2007;15(4):1703-7.
2007: Kan'ichiro Ishiuchi; Takaaki KUBOTA; Yuzuru Mikami; Yutaro Obara; Norimichi Nakahata; Jun'ichi Kobayashi
Complanadines C and D, new dimeric alkaloids from Lycopodium complanatum.
Bioorganic & medicinal chemistry 2007;15(1):413-7.
2006: Yuuko Kariya; Takaaki KUBOTA; Jane Fromont; Jun'ichi Kobayashi
Pyrinadines B-G, new bis-pyridine alkaloids with an azoxy moiety from sponge Cribrochalina sp.
Bioorganic & medicinal chemistry 2006;14(24):8415-9.
2006: Toshinori Kagata; Shizuka Saito; Hideyuki Shigemori; Ayumi Ohsaki; Haruaki Ishiyama; Takaaki KUBOTA; Jun'ichi Kobayashi
Paratunamides A-D, oxindole alkaloids from Cinnamodendron axillare.
Journal of natural products 2006;69(10):1517-21.
2006: Masashi Tsuda; Tetsuro Yasuda; Eri Fukushi; Jun Kawabata; Mitsuhiro Sekiguchi; Jane Fromont; Jun'ichi Kobayashi
Agesamides A and B, bromopyrrole alkaloids from sponge Agelas species: application of DOSY for chemical screening of new metabolites.
Organic letters 2006;8(19):4235-8.
2006: Hiroshi Morita; Toru Iizuka; Chee Yan Choo; Kit-Lam Chan; Koichi Takeya; Jun'ichi Kobayashi
Vasorelaxant activity of cyclic peptide, cyclosquamosin B, from Annona squamosa.
Bioorganic & medicinal chemistry letters 2006;16(17):4609-11.
2006: Kan'ichiro Ishiuchi; Takaaki KUBOTA; Tomohiro Hoshino; Yutaro Obara; Norimichi Nakahata; Jun'ichi Kobayashi
Lycopladines B-D and lyconadin B, new alkaloids from Lycopodium complanatum.
Bioorganic & medicinal chemistry 2006;14(17):5995-6000.
2006: Takaaki KUBOTA; Tetsuya Endo; Yohei Takahashi; Masashi Tsuda; Jun'ichi Kobayashi
Amphidinin B, a new polyketide metabolite from marine dinoflagellate Amphidinium sp.
The Journal of antibiotics 2006;59(8):512-6.
2006: Takaaki KUBOTA; Yoshiro Iinuma; Jun'ichi Kobayashi
Cloning of polyketide synthase genes from amphidinolide-producing dinoflagellate Amphidinium sp.
Biological & pharmaceutical bulletin 2006;29(7):1314-8.
2006: Hiroshi Morita; Nozomi Ishioka; Hiroshi Takatsu; Toru Iizuka; Jun'ichi Kobayashi
Daphmanidins E and F, alkaloids from Daphniphyllum teijsmannii.
Journal of natural products 2006;69(3):418-20.
2006: Kohei Nozawa; Masashi Tsuda; Haruaki Ishiyama; Takuma Sasaki; Takashi Tsuruo; Jun'ichi Kobayashi
Absolute stereochemistry and antitumor activity of iejimalides.
Bioorganic & medicinal chemistry 2006;14(4):1063-7.
2006: Yusuke Hirasawa; Jun'ichi Kobayashi; Hiroshi Morita
Lycoperine A, A novel C27N3-type pentacyclic alkaloid from Lycopodium hamiltonii, inhibiting acetylcholinesterase.
Organic letters 2006;8(1):123-6.
2005: Hiroshi Morita; Yusuke Hirasawa; Jun'ichi Kobayashi
Lycopodatines A-C, C(16)N alkaloids from Lycopodium inundatum.
Journal of natural products 2005;68(12):1809-12.
2005: Takao Mugishima; Masashi Tsuda; Yuu Kasai; Haruaki Ishiyama; Eri Fukushi; Jun Kawabata; Masayuki Watanabe; Kenichi Akao; Jun'ichi Kobayashi
Absolute stereochemistry of citrinadins a and B from marine-derived fungus.
The Journal of organic chemistry 2005;70(23):9430-5.
2005: Mai Sasaki; Masashi Tsuda; Mitsuhiro Sekiguchi; Yuzuru Mikami; Jun'ichi Kobayashi
Perinadine A, a novel tetracyclic alkaloid from marine-derived fungus Penicillium citrinum.
Organic letters 2005;7(19):4261-4.
2005: Kazutaka Shimbo; Kohei Nozawa; Masashi Tsuda; Jun'ichi Kobayashi
Solution conformations of amphidinolide H.
Bioorganic & medicinal chemistry 2005;13(17):5066-71.
2005: Masashi Tsuda; Yohei Takahashi; Jane Fromont; Yuzuru Mikami; Jun'ichi Kobayashi
Dendridine A, a bis-indole alkaloid from a marine sponge Dictyodendrilla Species.
Journal of natural products 2005;68(8):1277-8.
2005: Junko Takashima; Kanki Komiyama; Haruaki Ishiyama; Jun'ichi Kobayashi; Ayumi Ohsaki
Brosimacutins J-M, four new flavonoids from Brosimum acutifolium and their cytotoxic activity.
Planta medica 2005;71(7):654-8.
2005: Yoshiro Iinuma; Shingo Kozawa; Haruaki Ishiyama; Masashi Tsuda; Eri Fukushi; Jun Kawabata; Jane Fromont; Jun'ichi Kobayashi
Gesashidine A, a beta-carboline alkaloid with an imidazole ring from a Thorectidae sponge.
Journal of natural products 2005;68(7):1109-10.
2005: Hiroshi Morita; Izumi Machida; Yusuke Hirasawa; Jun'ichi Kobayashi
Taxezopidines M and N, taxoids from the Japanese yew, Taxus cuspidata.
Journal of natural products 2005;68(6):935-7.
2005: Yuu Kasai; Kazusei Komatsu; Hideyuki Shigemori; Masashi Tsuda; Yuzuru Mikami; Jun'ichi Kobayashi
Cladionol A, a polyketide glycoside from marine-derived fungus Gliocladium species.
Journal of natural products 2005;68(5):777-9.
2005: Kazusei Komatsu; Masashi Tsuda; Yasushi Tanaka; Yuzuru Mikami; Jun'ichi Kobayashi
SAR studies of brasilicardin A for immunosuppressive and cytotoxic activities.
Bioorganic & medicinal chemistry 2005;13(5):1507-13.
2005: Hiroshi Morita; Koichiro Koyama; Yoshikazu Sugimoto; Jun'ichi Kobayashi
Antimitotic activity and reversal of breast cancer resistance protein-mediated drug resistance by stilbenoids from Bletilla striata.
Bioorganic & medicinal chemistry letters 2005;15(4):1051-4.
2005: Hiroshi Morita; Khalijah Awang; A Hamid A Hadi; Koichi Takeya; Hideji Itokawa; Jun'ichi Kobayashi
Conformational analysis of rhazinilam and three-dimensional quantitative structure-activity relationships of rhazinilam analogues.
Bioorganic & medicinal chemistry letters 2005;15(4):1045-50.
2005: Hiroshi Morita; Nozomi Ishioka; Hiroshi Takatsu; Takakazu Shinzato; Yutaro Obara; Norimichi Nakahata; Jun'ichi Kobayashi
Daphmanidins C and D, novel pentacyclic alkaloids from Daphniphyllum teijsmanii.
Organic letters 2005;7(3):459-62.
2005: Masashi Tsuda; Mai Sasaki; Takao Mugishima; Kazusei Komatsu; Teruo Sone; Michiko Tanaka; Yuzuru Mikami; Jun'ichi Kobayashi
Scalusamides A-C, new pyrrolidine alkaloids from the marine-derived fungus Penicillium citrinum.
Journal of natural products 2005;68(2):273-6.
2005: Haruaki Ishiyama; Masashi Tsuda; Tadashi Endo; Jun'ichi Kobayashi
Asymmetric synthesis of double bond isomers of the structure proposed for pyrinodemin A and indication of its structural revision.
Molecules (Basel, Switzerland) 2005;10(1):312-6.
2005: Jun'ichi Kobayashi; Hiroshi Morita
The Lycopodium alkaloids.
The Alkaloids. Chemistry and biology 2005;61():1-57.
2004: Kazusei Komatsu; Masashi Tsuda; Motoo Shiro; Yasushi Tanaka; Yuzuru Mikami; Jun'ichi Kobayashi
Brasilicardins B-D, new tricyclic terpenoids [correction of terpernoids] from actinomycete Nocardia brasiliensis.
Bioorganic & medicinal chemistry 2004;12(21):5545-51.
2004: Yusuke Hirasawa; Hiroshi Morita; Jun'ichi Kobayashi
Nankakurine A, a novel C16N2-type alkaloid from Lycopodium hamiltonii.
Organic letters 2004;6(19):3389-91.
2004: Masashi Tsuda; Yuu Kasai; Kazusei Komatsu; Teruo Sone; Michiko Tanaka; Yuzuru Mikami; Jun'ichi Kobayashi
Citrinadin A, a novel pentacyclic alkaloid from marine-derived fungus Penicillium citrinum.
Organic letters 2004;6(18):3087-9.
2004: Hiroshi Morita; Hayato Suzuki; Jun'ichi Kobayashi
Celogenamide A, a new cyclic peptide from the seeds of Celosia argentea.
Journal of natural products 2004;67(9):1628-30.
2004: Tadashi Endo; Masashi Tsuda; Tadashi Okada; Shinya Mitsuhashi; Hiroshi Shima; Kunimi Kikuchi; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi
Nagelamides A-H, new dimeric bromopyrrole alkaloids from marine sponge Agelas species.
Journal of natural products 2004;67(8):1262-7.
2004: Hiroshi Morita; Tomoka Dota; Jun'ichi Kobayashi
Antimitotic activity of glaupalol-related coumarins from Glaucidium palmatum.
Bioorganic & medicinal chemistry letters 2004;14(14):3665-8.
2004: Kazusei Komatsu; Masashi Tsuda; Yasushi Tanaka; Yuzuru Mikami; Jun'ichi Kobayashi
Absolute stereochemistry of immunosuppressive macrolide brasilinolide A and its new congener brasilinolide C.
The Journal of organic chemistry 2004;69(5):1535-41.
2004: Jun'ichi Kobayashi; Masashi Tsuda
Amphidinolides, bioactive macrolides from symbiotic marine dinoflagellates.
Natural product reports 2004;21(1):77-93.
2003: Masashi Tsuda; Naoko Izui; Kazutaka Shimbo; Masaaki Sato; Eri Fukushi; Jun Kawabata; Jun'ichi Kobayashi
Amphidinolide Y, a novel 17-membered macrolide from dinoflagellate Amphidinium sp.: plausible biogenetic precursor of amphidinolide X.
The Journal of organic chemistry 2003;68(23):9109-12.
2003: Yusuke Hirasawa; Hiroshi Morita; Motoo Shiro; Jun'ichi Kobayashi
Sieboldine A, a novel tetracyclic alkaloid from Lycopodium sieboldii, inhibiting acetylcholinesterase.
Organic letters 2003;5(21):3991-3.
2003: Hiroshi Morita; Jun'ichi Kobayashi
Calyciphyllines A and B, two novel hexacyclic alkaloids from Daphniphyllum calycinum.
Organic letters 2003;5(16):2895-8.
2003: Masashi Tsuda; Naoko Izui; Kazutaka Shimbo; Masaaki Sato; Eri Fukushi; Jun Kawabata; Kazuhito Katsumata; Takeo Horiguchi; Jun'ichi Kobayashi
Amphidinolide X, a novel 16-membered macrodiolide from dinoflagellate Amphidinium sp.
The Journal of organic chemistry 2003;68(13):5339-45.
2003: Hiroshi Morita; Yusuke Hirasawa; Jun'ichi Kobayashi
Himeradine A, a novel C27N3-type alkaloid from Lycopodium chinense.
The Journal of organic chemistry 2003;68(11):4563-6.
2003: Jun'ichi Kobayashi; Hiroshi Takatsu; Ya-Ching Shen; Hiroshi Morita
Daphniglaucins A and B, novel polycyclic quaternary alkaloids from Daphniphyllum glaucescens.
Organic letters 2003;5(10):1733-6.
2003: Masashi Tsuda; Yuki Toriyabe; Tetsuya Endo; Jun'ichi Kobayashi
Application of modified Mosher's method for primary alcohols with a methyl group at C2 position.
Chemical & pharmaceutical bulletin 2003;51(4):448-51.
2003: Masashi Tsuda; Takao Mugishima; Kazusei Komatsu; Teruo Sone; Michiko Tanaka; Yuzuru Mikami; Jun'ichi Kobayashi
Modiolides A and B, two new 10-membered macrolides from a marine-derived fungus.
Journal of natural products 2003;66(3):412-5.
2003: Masashi Tsuda; Kohei Nozawa; Kazutaka Shimbo; Jun'ichi Kobayashi
Rigidins B-D, new pyrrolopyrimidine alkaloids from a tunicate Cystodytes species.
Journal of natural products 2003;66(2):292-4.
2003: Jun'ichi Kobayashi; Hiroshi Morita
The Daphniphyllum alkaloids.
The Alkaloids. Chemistry and biology 2003;60():165-205.
2003: Hideyuki Shigemori; Toshinori Kagata; Haruaki Ishiyama; Frank Morah; Ayumi Ohsaki; Jun'ichi Kobayashi
Naucleamides A-E, new monoterpene indole alkaloids from Nauclea latifolia.
Chemical & pharmaceutical bulletin 2003;51(1):58-61.
2002: Masashi Tsuda; Tadashi Endo; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi
Luffariolides H and J, new sesterterpenes from a marine sponge Luffariella species.
Journal of natural products 2002;65(10):1507-8.
2002: Jun'ichi Kobayashi; Kazutaka Shimbo; Masaaki Sato; Masashi Tsuda
Amphidinolides H2-H5, G2, and G3, new cytotoxic 26- and 27-membered macrolides from dinoflagellate Amphidinium sp.
The Journal of organic chemistry 2002;67(19):6585-92.
2002: Jun'ichi Kobayashi; Satoshi Ueno; Hiroshi Morita
Daphmanidin A, a novel hexacyclic alkaloid from Daphniphyllum teijsmanii.
The Journal of organic chemistry 2002;67(18):6546-9.
2002: Jun'ichi Kobayashi; Mitsuhiro Sekiguchi; Sayaka Shimamoto; Hideyuki Shigemori; Haruaki Ishiyama; Ayumi Ohsaki
Subincanadines A-C, novel quaternary indole alkaloids from Aspidosperma subincanum.
The Journal of organic chemistry 2002;67(18):6449-55.
2002: Hiroshi Morita; Jun'ichi Kobayashi
A biomimetic transformation of serratinine into serratezomine A through a modified Polonovski reaction.
The Journal of organic chemistry 2002;67(15):5378-81.
2002: Masashi Tsuda; Naoko Izui; Masaaki Sato; Jun'ichi Kobayashi
Biosynthetic study of amphidinolide W.
Chemical & pharmaceutical bulletin 2002;50(7):976-7.
2002: Jun'ichi Kobayashi; Hideyuki Shigemori
Bioactive taxoids from the Japanese yew Taxus cuspidata.
Medicinal research reviews 2002;22(3):305-28.
2002: Jun'ichi Kobayashi; Miwa Yoshinaga; Naotoshi Yoshida; Motoo Shiro; Hiroshi Morita
Cephalocyclidin A, a novel pentacyclic alkaloid from Cephalotaxus harringtonia var. nana.
The Journal of organic chemistry 2002;67(7):2283-6.
2002: Hiroshi Morita; Naotoshi Yoshida; Jun'ichi Kobayashi
Daphnicyclidins J and K, unique polycyclic alkaloids from Daphniphyllum humile.
The Journal of organic chemistry 2002;67(7):2278-82.
2002: Takaaki KUBOTA; Masashi Tsuda; Jun'ichi Kobayashi
Absolute stereochemistry of amphidinolide E.
The Journal of organic chemistry 2002;67(5):1651-6.
2002: Mitsuhiro Sekiguchi; Hideyuki Shigemori; Ayumi Ohsaki; Jun'ichi Kobayashi
Renealtins A and B, new diarylheptanoids with a tetrahydrofuran ring from the seeds of Renealmia exaltata.
Journal of natural products 2002;65(3):375-6.
2002: Kazutaka Shimbo; Masashi Tsuda; Naoko Izui; Jun'ichi Kobayashi
Amphidinolide W, a new 12-membered macrolide from dinoflagellate Amphidinium sp.
The Journal of organic chemistry 2002;67(3):1020-3.
2002: Hideyuki Shigemori; Sayaka Shimamoto; Mitsuhiro Sekiguchi; Ayumi Ohsaki; Jun'ichi Kobayashi
Echinodolides A and B, new cembrane diterpenoids with an eight-membered lactone ring from the leaves of Echinodorus macrophyllus.
Journal of natural products 2002;65(1):82-4.
2001: Jun'ichi Kobayashi; Y Inaba; M Shiro; N Yoshida; Hiroshi Morita
Daphnicyclidins A-H, novel hexa- or pentacyclic alkaloids from two species of Daphniphyllum.
Journal of the American Chemical Society 2001;123(46):11402-8.
2001: Jun'ichi Kobayashi; H Suzuki; Kazutaka Shimbo; Koichi Takeya; Hiroshi Morita
Celogentins A-C, new antimitotic bicyclic peptides from the seeds of Celosia argentea.
The Journal of organic chemistry 2001;66(20):6626-33.
2001: Masashi Tsuda; Takaaki KUBOTA; Y Sakuma; Jun'ichi Kobayashi
Biosynthetic study of amphidinolide B.
Chemical & pharmaceutical bulletin 2001;49(10):1366-7.
2001: Kazusei Komatsu; Hideyuki Shigemori; Jun'ichi Kobayashi
Dictyonamides A and B, new peptides from marine-derived fungus.
The Journal of organic chemistry 2001;66(18):6189-92.
2001: Jun'ichi Kobayashi; Yusuke Hirasawa; Naotoshi Yoshida; Hiroshi Morita
Lyconadin A, a novel alkaloid from Lycopodium complanatum.
The Journal of organic chemistry 2001;66(17):5901-4.
2001: Mitsuhiro Sekiguchi; Hideyuki Shigemori; Ayumi Ohsaki; Jun'ichi Kobayashi
Pacovatinins A-C, new labdane diterpenoids from the seeds of Renealmia exaltata.
Journal of natural products 2001;64(8):1102-6.
2001: Masashi Tsuda; Y Sakuma; Jun'ichi Kobayashi
Suberedamines A and B, new bromotyrosine alkaloids from a sponge Suberea species.
Journal of natural products 2001;64(7):980-2.
2001: Takaaki KUBOTA; Masashi Tsuda; Jun'ichi Kobayashi
Absolute stereochemistry of amphidinolide C.
Organic letters 2001;3(9):1363-6.
2001: Jun'ichi Kobayashi; Takaaki KUBOTA; Tetsuya Endo; Masashi Tsuda
Amphidinolides T2, T3, and T4, new 19-membered macrolides from the dinoflagellate Amphidinium sp. and the biosynthesis of amphidinolide T1.
The Journal of organic chemistry 2001;66(1):134-42.
2000: Hiroshi Morita; Yoshihiro Sato; Kit-Lam Chan; Chee Yan Choo; Hideji Itokawa; Koichi Takeya; Jun'ichi Kobayashi
Samoquasine A, a benzoquinazoline alkaloid from the seeds of Annona squamosa.
Journal of natural products 2000;63(12):1707-8.
2000: Jun'ichi Kobayashi; Mitsuhiro Sekiguchi; Sayaka Shimamoto; Hideyuki Shigemori; Ayumi Ohsaki
Echinophyllins C-F, new nitrogen-containing clerodane diterpenoids from Echinodorus macrophyllus.
Journal of natural products 2000;63(11):1576-9.
2000: Takaaki KUBOTA; Masashi Tsuda; M Takahashi; M Ishibashi; S Oka; Jun'ichi Kobayashi
Colopsinols D and E, new polyhydroxyl linear carbon chain compounds from marine dinoflagellate Amphidinium sp.
Chemical & pharmaceutical bulletin 2000;48(10):1447-51.
2000: Hiroshi Morita; M Arisaka; Naotoshi Yoshida; Jun'ichi Kobayashi
Serratezomines A--C, new alkaloids from Lycopodium serratum var. serratum.
The Journal of organic chemistry 2000;65(19):6241-5.
2000: Jun'ichi Kobayashi; Kazutaka Shimbo; Masaaki Sato; Motoo Shiro; Masashi Tsuda
Absolute stereochemistry of amphidinolides G and H.
Organic letters 2000;2(18):2805-7.
2000: Hajime Kubo; Jun'ichi Kobayashi; Kimio Higashiyama; Junzo Kamei; Y Fujii; S Ohmiya
The hypoglycemic effect of (7R*,9aS*)-7-phenyl-octahydroquinolizin-2-one in mice.
Biological & pharmaceutical bulletin 2000;23(9):1114-7.
2000: K Hirano; Takaaki KUBOTA; Masashi Tsuda; Yuzuru Mikami; Jun'ichi Kobayashi
Pyrinodemins B-D, potent cytotoxic bis-pyridine alkaloids from marine sponge amphimedon sp.
Chemical & pharmaceutical bulletin 2000;48(7):974-7.
2000: Hiroshi Morita; Naotoshi Yoshida; Jun'ichi Kobayashi
Daphnezomines F and G: novel alkaloids with 1-azabicyclo[5.2. 2]undecane moiety from Daphniphyllum humile.
The Journal of organic chemistry 2000;65(11):3558-62.
2000: Jun'ichi Kobayashi; Hideyuki Shigemori; H Hosoyama; Z Chen; S Akiyama; M Naito; Takashi Tsuruo
Multidrug resistance reversal activity of taxoids from Taxus cuspidata in KB-C2 and 2780AD cells.
Japanese journal of cancer research : Gann 2000;91(6):638-42.
2000: Toshinori Kagata; Hideyuki Shigemori; Yuzuru Mikami; Jun'ichi Kobayashi
Coruscol A, a new metabolite from the marine-derived fungus penicillium species.
Journal of natural products 2000;63(6):886-7.
2000: Masashi Tsuda; Tetsuya Endo; Jun'ichi Kobayashi
Amphidinolide T, novel 19-membered macrolide from marine dinoflagellate Amphidinium sp.
The Journal of organic chemistry 2000;65(5):1349-52.
2000: Hiroshi Morita; Kazutaka Shimbo; Hideyuki Shigemori; Jun'ichi Kobayashi
Antimitotic activity of moroidin, a bicyclic peptide from the seeds of Celosia argentea.
Bioorganic & medicinal chemistry letters 2000;10(5):469-71.
2000: Kazusei Komatsu; Hideyuki Shigemori; Yuzuru Mikami; Jun'ichi Kobayashi
Sculezonones A and B, two metabolites possessing a phenalenone skeleton from a marine-derived fungus Penicillium species.
Journal of natural products 2000;63(3):408-9.
2000: Jun'ichi Kobayashi; Mitsuhiro Sekiguchi; Hideyuki Shigemori; Ayumi Ohsaki
Chapecoderins A-C, new labdane-derived diterpenoids from Echinodorus macrophyllus.
Journal of natural products 2000;63(3):375-7.
1999: H Hosoyama; Hideyuki Shigemori; A Tomida; Takashi Tsuruo; Jun'ichi Kobayashi
Modulation of multidrug resistance in tumor cells by taxinine derivatives.
Bioorganic & medicinal chemistry letters 1999;9(3):389-94.
1998: Jun'ichi Kobayashi; H Hosoyama; X X Wang; Hideyuki Shigemori; Y Sudo; Takashi Tsuruo
Modulation of multidrug resistance by taxuspine C and other taxoids from Japanese yew.
Bioorganic & medicinal chemistry letters 1998;8(12):1555-8.
1997: Jun'ichi Kobayashi; M Tsuda; A Nemoto; Y Tanaka; K Yazawa; Y Mikami
Brasilidine A, a new cytotoxic isonitrile-containing indole alkaloid from the actinomycete Nocardia brasiliensis.
Journal of natural products 1997;60(7):719-20.
1997: Jun'ichi Kobayashi
[Search for new MDR modifier possessing taxane skeleton].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(5):1135-42.
1995: Jun'ichi Kobayashi; H Hosoyama; Hideyuki Shigemori; Y Koiso; S Iwasaki
Taxuspine D, a new taxane diterpene from Taxus cuspidata with potent inhibitory activity against Ca(2+)-induced depolymerization of microtubules.
Experientia 1995;51(6):592-5.
1995: Jun'ichi Kobayashi; H Shinonaga; Hideyuki Shigemori
Xestobergsterol C, a new pentacyclic steroid from the Okinawan marine sponge Ircinia Sp. and absolute stereochemistry of xestobergsterol A.
Journal of natural products 1995;58(2):312-8.
1994: Jun'ichi Kobayashi; M Tsuda; N Kawasaki; T Sasaki; Y Mikami
6-Hydroxymanzamine A and 3,4-dihydromanzamine A, new alkaloids from the Okinawan marine sponge Amphimedon Sp.
Journal of natural products 1994;57(12):1737-40.
1994: H Shinonaga; Hideyuki Shigemori; Jun'ichi Kobayashi
Konbamidin, a new indole alkaloid from the Okinawan marine sponge Ircinia sp.
Journal of natural products 1994;57(11):1603-5.
1994: Jun'ichi Kobayashi; K Naitoh; K Ishida; Hideyuki Shigemori; M Ishibashi
Nepheliosyne A, new C47 acetylenic acid from the Okinawan marine sponge Xestospongia sp.
Journal of natural products 1994;57(9):1300-3.
1994: K Kondo; J Nishi; M Ishibashi; Jun'ichi Kobayashi
Two new tryptophan-derived alkaloids from the Okinawan marine sponge Aplysina sp.
Journal of natural products 1994;57(7):1008-11.
1993: Y Doi; Hideyuki Shigemori; M Ishibashi; F Mizobe; A Kawashima; S Nakaike; Jun'ichi Kobayashi
New sesterterpenes with nerve growth factor synthesis-stimulating activity from the Okinawan marine sponge Hyrtios sp.
Chemical & pharmaceutical bulletin 1993;41(12):2190-1.
1993: C M Zeng; M Ishibashi; Jun'ichi Kobayashi
Biemnasterol, a new cytotoxic sterol with the rare 22,25-diene side chain, isolated from the marine sponge Biemna sp.
Journal of natural products 1993;56(11):2016-8.
1993: Jun'ichi Kobayashi; C M Zeng; M Ishibashi; T Sasaki
Luffariolides F and G, new manoalide derivatives from the Okinawan marine sponge Luffariella sp.
Journal of natural products 1993;56(3):436-9.
1992: K Ishida; M Ishibashi; Hideyuki Shigemori; T Sasaki; Jun'ichi Kobayashi
Agelasine G, a new antileukemic alkaloid from the Okinawan marine sponge Agelas sp.
Chemical & pharmaceutical bulletin 1992;40(3):766-7.
1991: Jun'ichi Kobayashi; M Tsuda; A Tanabe; M Ishibashi; J F Cheng; S Yamamura; T Sasaki
Cystodytins D-I, new cytotoxic tetracyclic aromatic alkaloids from the Okinawan marine tunicate Cystodytes dellechiajei.
Journal of natural products 1991;54(6):1634-8.
1991: Jun'ichi Kobayashi; M Tsuda; M Ishibashi; Hideyuki Shigemori; T Yamasu; H Hirota; T Sasaki
Amphidinolide F, a new cytotoxic macrolide from the marine dinoflagellate Amphidinium sp.
The Journal of antibiotics 1991;44(11):1259-61.
1991: Jun'ichi Kobayashi; J F Cheng; H Nakamura; Y Ohizumi; Y Tomotake; T Matsuzaki; K J Grace; Robert S Jacobs; Y Kato; L S Brinen
Structure and stereochemistry of brianolide, a new antiinflammatory diterpenoid from the Okinawan gorgonian Briareum sp.
Experientia 1991;47(5):501-2.
1991: Jun'ichi Kobayashi; M Tsuda; Y Ohizumi
A potent actomyosin ATPase activator from the Okinawan marine sponge Agelas cf. nemoechinata.
Experientia 1991;47(3):301-4.