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Onno Bakker

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I Stoykov; Hermina C van Beeren; Antoon F M Moorman; Vincent M Christoffels; Wilmar M Wiersinga; Onno Bakker
Effect of amiodarone and dronedarone administration in rats on thyroid hormone-dependent gene expression in different cardiac components.
Richard Keijzer; Piet-Jan E Blommaart; Wil T Labruyère; Jacqueline L M Vermeulen; Behrouz Zandieh Doulabi; Onno Bakker; Dick Tibboel; Wouter H Lamers
Expression of thyroid hormone receptors A and B in developing rat tissues; evidence for extensive posttranscriptional regulation.
Daphne C Thijssen-Timmer; Robin P Peeters; Patrick F Wouters; Frank Weekers; Theo J Visser; Eric Fliers; Wilmar M Wiersinga; Onno Bakker; Greet Van Den Berghe
Thyroid hormone receptor isoform expression in livers of critically ill patients.

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All Publications

2007: I Stoykov; Hermina C van Beeren; Antoon F M Moorman; Vincent M Christoffels; Wilmar M Wiersinga; Onno Bakker
Effect of amiodarone and dronedarone administration in rats on thyroid hormone-dependent gene expression in different cardiac components.
European journal of endocrinology / European Federation of Endocrine Societies 2007;156(6):695-702.
2007: Richard Keijzer; Piet-Jan E Blommaart; Wil T Labruyère; Jacqueline L M Vermeulen; Behrouz Zandieh Doulabi; Onno Bakker; Dick Tibboel; Wouter H Lamers
Expression of thyroid hormone receptors A and B in developing rat tissues; evidence for extensive posttranscriptional regulation.
Journal of molecular endocrinology 2007;38(5):523-35.
2007: Daphne C Thijssen-Timmer; Robin P Peeters; Patrick F Wouters; Frank Weekers; Theo J Visser; Eric Fliers; Wilmar M Wiersinga; Onno Bakker; Greet Van Den Berghe
Thyroid hormone receptor isoform expression in livers of critically ill patients.
Thyroid : official journal of the American Thyroid Association 2007;17(2):105-12.
2006: Daphne C Thijssen-Timmer; M Platvoet-Ter Schiphorst; Joan Kwakkel; Roger Emter; Anastasia Kralli; Wilmar M Wiersinga; Onno Bakker
PGC-1alpha regulates the isoform mRNA ratio of the alternatively spliced thyroid hormone receptor alpha transcript.
Journal of molecular endocrinology 2006;37(2):251-7.
2006: I Stoykov; Behrouz Zandieh Doulabi; Antoon F M Moorman; Vincent M Christoffels; Wilmar M Wiersinga; Onno Bakker
Expression pattern and ontogenesis of thyroid hormone receptor isoforms in the mouse heart.
The Journal of endocrinology 2006;189(2):231-45.
2005: Anneke Alkemade; Chrétienne L Vuijst; Unga A Unmehopa; Onno Bakker; Björn Vennström; Wilmar M Wiersinga; Dick F Swaab; Eric Fliers
Thyroid hormone receptor expression in the human hypothalamus and anterior pituitary.
The Journal of clinical endocrinology and metabolism 2005;90(2):904-12.
2005: Leon Brokken; Onno Bakker; Wilmar M Wiersinga; Mark F Prummel
Functional thyrotropin receptor expression in the pituitary folliculo-stellate cell line TtT/GF.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2005;113(1):13-20.
2004: Leon Brokken; M Leendertse; Onno Bakker; Wilmar M Wiersinga; Mark F Prummel
Expression of adenohypophyseal-hormone receptors in a murine folliculo-stellate cell line.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(8):538-41.
2004: Behrouz Zandieh Doulabi; Marianne Platvoet-ter Schiphorst; Andries Kalsbeek; Wilmar M Wiersinga; Onno Bakker
Hyper and hypothyroidism change the expression and diurnal variation of thyroid hormone receptor isoforms in rat liver without major changes in their zonal distribution.
Molecular and cellular endocrinology 2004;219(1-2):69-75.
2004: Behrouz Zandieh Doulabi; Marianne Platvoet-ter Schiphorst; Andries Kalsbeek; Eric Fliers; Onno Bakker; Wilmar M Wiersinga
Diurnal variation in rat liver thyroid hormone receptor (TR)-alpha messenger ribonucleic acid (mRNA) is dependent on the biological clock in the suprachiasmatic nucleus, whereas diurnal variation of TR beta 1 mRNA is modified by food intake.
Endocrinology 2004;145(3):1284-9.
2003: Behrouz Zandieh Doulabi; E Dop; M Schneiders; M P-T Schiphorst; A Mansen; Björn Vennström; C D Dijkstra; Onno Bakker; Wilmar M Wiersinga
Zonal expression of the thyroid hormone receptor alpha isoforms in rodent liver.
The Journal of endocrinology 2003;179(3):379-85.
2003: D C Timmer; Onno Bakker; Wilmar M Wiersinga
Triiodothyronine affects the alternative splicing of thyroid hormone receptor alpha mRNA.
The Journal of endocrinology 2003;179(2):217-25.
2003: Iris M M J Wakelkamp; Onno Bakker; Lelio Baldeschi; Wilmar M Wiersinga; Mark F Prummel
TSH-R expression and cytokine profile in orbital tissue of active vs. inactive Graves' ophthalmopathy patients.
Clinical endocrinology 2003;58(3):280-7.
2003: Hermina C van Beeren; W M C Jong; Ellen Kaptein; Theo J Visser; Onno Bakker; Wilmar M Wiersinga
Dronerarone acts as a selective inhibitor of 3,5,3'-triiodothyronine binding to thyroid hormone receptor-alpha1: in vitro and in vivo evidence.
Endocrinology 2003;144(2):552-8.
2002: Frank W J S Wassen; Anja E Schiel; George G J M Kuiper; Ellen Kaptein; Onno Bakker; Theo J Visser; Warner S Simonides
Induction of thyroid hormone-degrading deiodinase in cardiac hypertrophy and failure.
Endocrinology 2002;143(7):2812-5.
2002: C H J Verhoelst; Kristien Vandenborne; T Severi; Onno Bakker; Behrouz Zandieh Doulabi; JL Leonard; Eduard R Kühn; Serge Van Der Geyten; Veerle M Darras
Specific detection of type III iodothyronine deiodinase protein in chicken cerebellar purkinje cells.
Endocrinology 2002;143(7):2700-7.
2002: Behrouz Zandieh Doulabi; Marianne Platvoet-ter Schiphorst; Hermina C van Beeren; Wil T Labruyere; Wouter H Lamers; Eric Fliers; Onno Bakker; Wilmar M Wiersinga
TR(beta)1 protein is preferentially expressed in the pericentral zone of rat liver and exhibits marked diurnal variation.
Endocrinology 2002;143(3):979-84.
2002: Jeroen Lips; Steven W de Jager; Peter de Haan; Onno Bakker; Ivo Vanicky; Michael J Jacobs; Cor Kalkman
Peri-ischemic aminoguanidine fails to ameliorate neurologic and histopathologic outcome after transient spinal cord ischemia.
Journal of neurosurgical anesthesiology 2002;14(1):35-42.
2001: Andries Kalsbeek; Eric Fliers; Johannes A Romijn; Susanne E La Fleur; Joke Wortel; Onno Bakker; E Endert; Ruud M Buijs
The suprachiasmatic nucleus generates the diurnal changes in plasma leptin levels.
Endocrinology 2001;142(6):2677-85.
2001: MJ Diekman; Behrouz Zandieh Doulabi; Marianne Platvoet-ter Schiphorst; Eric Fliers; Onno Bakker; Wilmar M Wiersinga
The biological relevance of thyroid hormone receptors in immortalized human umbilical vein endothelial cells.
The Journal of endocrinology 2001;168(3):427-33.
2000: Mark F Prummel; Leon Brokken; G Meduri; Micheline Misrahi; Onno Bakker; Wilmar M Wiersinga
Expression of the thyroid-stimulating hormone receptor in the folliculo-stellate cells of the human anterior pituitary.
The Journal of clinical endocrinology and metabolism 2000;85(11):4347-53.
2000: Hermina C van Beeren; Onno Bakker; Wilmar M Wiersinga
Desethylamiodarone interferes with the binding of co-activator GRIP-1 to the beta 1-thyroid hormone receptor.
FEBS letters 2000;481(3):213-6.
2000: Peter de Haan; Ivo Vanicky; Michael J Jacobs; Onno Bakker; Jeroen Lips; SA Meylaerts; Cor Kalkman
Effect of ischemic pretreatment on heat shock protein 72, neurologic outcome, and histopathologic outcome in a rabbit model of spinal cord ischemia.
The Journal of thoracic and cardiovascular surgery 2000;120(3):513-9.
2000: MJ Diekman; N Anghelescu; Erik Endert; Onno Bakker; Wilmar M Wiersinga
Changes in plasma low-density lipoprotein (LDL)- and high-density lipoprotein cholesterol in hypo- and hyperthyroid patients are related to changes in free thyroxine, not to polymorphisms in LDL receptor or cholesterol ester transfer protein genes.
The Journal of clinical endocrinology and metabolism 2000;85(5):1857-62.
2000: AJ Vriesema; Henry Beekhuizen; M Hamdi; Alexandre T Soufan; aart lammers; B Willekens; Onno Bakker; A G Welten; Marcel H A M Veltrop; Joke S van de Gevel; Jacob Dankert; Sebastian A J Zaat
Altered gene expression in Staphylococcus aureus upon interaction with human endothelial cells.
Infection and immunity 2000;68(4):1765-72.
2000: Martin N Gerding; J W C van der Meer; M Broenink; Onno Bakker; Wilmar M Wiersinga; Mark F Prummel
Association of thyrotrophin receptor antibodies with the clinical features of Graves' ophthalmopathy.
Clinical endocrinology 2000;52(3):267-71.
1999: Onno Bakker; Hermina C van Beeren; T Emrich; H Höltke; Wilmar M Wiersinga
Interaction between nuclear hormone receptors and coactivators analyzed using a nonradioactive "Pull-Down" assay.
Analytical biochemistry 1999;276(1):105-6.
1999: Hermina C van Beeren; Onno Bakker; V K Chatterjee; Wilmar M Wiersinga
Effect of mutations in the beta1-thyroid hormone receptor on the inhibition of T3 binding by desethylamiodarone.
FEBS letters 1999;450(1-2):35-8.
1998: F Hudig; Onno Bakker; Wilmar M Wiersinga
Amiodarone decreases gene expression of low-density lipoprotein receptor at both the mRNA and the protein level.
Metabolism: clinical and experimental 1998;47(9):1052-7.
1998: Onno Bakker; F Hudig; S Meijssen; Wilmar M Wiersinga
Effects of triiodothyronine and amiodarone on the promoter of the human LDL receptor gene.
Biochemical and biophysical research communications 1998;249(2):517-21.
1998: A M van der Wal; Onno Bakker; Wilmar M Wiersinga
The decrease of liver LDL receptor mRNA during fasting is related to the decrease in serum T3.
The international journal of biochemistry & cell biology 1998;30(2):209-15.
1998: Onno Bakker; H Razaki; J de Jong; C Ris-Stalpers; Wilmar M Wiersinga
Expression of the alpha 1, alpha 2, and beta 1 T3-receptor mRNAs in the fasted rat measured using competitive PCR.
Biochemical and biophysical research communications 1998;242(3):492-6.
1997: Mark F Prummel; Y Van Pareren; Onno Bakker; Wilmar M Wiersinga
Anti-heat shock protein (hsp)72 antibodies are present in patients with Graves' disease (GD) and in smoking control subjects.
Clinical and experimental immunology 1997;110(2):292-5.
1997: F Hudig; Onno Bakker; Wilmar M Wiersinga
Tri-iodothyronine prevents the amiodarone-induced decrease in the expression of the liver low-density lipoprotein receptor gene.
The Journal of endocrinology 1997;152(3):413-21.
1996: Hermina C van Beeren; Onno Bakker; Wilmar M Wiersinga
Structure-function relationship of the inhibition of the 3,5,3'-triiodothyronine binding to the alpha1- and beta1-thyroid hormone receptor by amiodarone analogs.
Endocrinology 1996;137(7):2807-14.
1995: A Boelen; M C Platvoet-ter Schiphorst; Onno Bakker; Wilmar M Wiersinga
The role of cytokines in the lipopolysaccharide-induced sick euthyroid syndrome in mice.
The Journal of endocrinology 1995;146(3):475-83.
1995: Hermina C van Beeren; Onno Bakker; Wilmar M Wiersinga
Desethylamiodarone is a competitive inhibitor of the binding of thyroid hormone to the thyroid hormone alpha 1-receptor protein.
Molecular and cellular endocrinology 1995;112(1):15-9.
1995: M T den Hartog; C C Sijmons; Onno Bakker; Carrie Ris Stalpers; Jan J M de Vijlder
Importance of the content and localization of tyrosine residues for thyroxine formation within the N-terminal part of human thyroglobulin.
European journal of endocrinology / European Federation of Endocrine Societies 1995;132(5):611-7.
1994: Onno Bakker; Hermina C van Beeren; Wilmar M Wiersinga
Desethylamiodarone is a noncompetitive inhibitor of the binding of thyroid hormone to the thyroid hormone beta 1-receptor protein.
Endocrinology 1994;134(4):1665-70.
1994: F Hudig; Onno Bakker; Wilmar M Wiersinga
Amiodarone-induced hypercholesterolemia is associated with a decrease in liver LDL receptor mRNA.
FEBS letters 1994;341(1):86-90.
1993: M T den Hartog; C C Sijmons; P M Kristel; Onno Bakker; Jan J M de Vijlder
Expression of a functional thyroglobulin fragment in a baculovirus system.
Journal of molecular endocrinology 1993;11(2):161-6.