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Cameron Koch

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Lilie L Lin; Ramesh Rengan; Antti Silvoniemi; Olof Solin; Jonathan M Sorger; Michael G Stabin; James B Stubbs; Sami Suilamo; Chaitanya Divgi; Olli Eskola; Sydney M Evans; Sarita Forsback; Tove J Grönroos; Stephen M Hahn; Alexander V Kachur; Cameron J Koch; Heikki Minn
Radiation dosimetry and biodistribution of the hypoxia tracer (18)F-EF5 in oncologic patients.
Sydney M Evans; Cameron J Koch
Re: Devic et al. (Int J Radiat Oncol Biol Phys 2010;78:1555-1562).
Cameron J Koch; Sydney M Evans
In regard to Brown et al. (Int J Radiat Oncol Biol Phys 2010;78:323-327).

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2012: Lilie L Lin; Ramesh Rengan; Antti Silvoniemi; Olof Solin; Jonathan M Sorger; Michael G Stabin; James B Stubbs; Sami Suilamo; Chaitanya Divgi; Olli Eskola; Sydney M Evans; Sarita Forsback; Tove J Grönroos; Stephen M Hahn; Alexander V Kachur; Cameron J Koch; Heikki Minn
Radiation dosimetry and biodistribution of the hypoxia tracer (18)F-EF5 in oncologic patients.
Cancer biotherapy & radiopharmaceuticals 2012;27(7):412-9.
2011: Sydney M Evans; Cameron J Koch
Re: Devic et al. (Int J Radiat Oncol Biol Phys 2010;78:1555-1562).
International journal of radiation oncology, biology, physics 2011;81(3):902; author reply 902-3.
2011: Cameron J Koch; Sydney M Evans
In regard to Brown et al. (Int J Radiat Oncol Biol Phys 2010;78:323-327).
International journal of radiation oncology, biology, physics 2011;80(5):1604-5; author reply 1605.
2010: Cameron J Koch; Joshua S Scheuermann; Chaitanya R Divgi; Kevin D Judy; Alexander V Kachur; Richard Freifelder; Janet S Reddin; Joel Karp; James B Stubbs; Stephen M Hahn; Jason Driesbaugh; Deborah Smith; Susan Prendergast; Sydney M Evans
Biodistribution and dosimetry of (18)F-EF5 in cancer patients with preliminary comparison of (18)F-EF5 uptake versus EF5 binding in human glioblastoma.
European journal of nuclear medicine and molecular imaging 2010;37(11):2048-59.
2010: Seung-Cheol Lee; harish poptani; Stephen Pickup; W Timothy Jenkins; Sungheon Kim; Cameron J Koch; Edward Delikatny; Jerry D Glickson
Early detection of radiation therapy response in non-Hodgkin's lymphoma xenografts by in vivo 1H magnetic resonance spectroscopy and imaging.
NMR in biomedicine 2010;23(6):624-32.
2010: Alexander V Kachur; William R Dolbier; Wei Xu; Cameron J Koch
Catalysis of fluorine addition to double bond: an improvement of method for synthesis of (18)F PET agents.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2010;68(2):293-6.
2010: Mary A Robinson; Stephen W Tuttle; Cynthia M Otto; Cameron J Koch
pO(2)-dependent NO production determines OPPC activity in macrophages.
Free radical biology & medicine 2010;48(2):189-95.
2010: Sydney M Evans; Kevin W Jenkins; H Isaac Chen; W Timothy Jenkins; Kevin D Judy; Wei-Ting Hwang; Robert A Lustig; Alexander R Judkins; M Sean Grady; Stephen M Hahn; Cameron J Koch
The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study.
Translational oncology 2010;3(3):160-9.
2009: George J Cerniglia; N Pore; Jeff H Tsai; Susan Schultz; Rosemarie Mick; Regine Choe; Xiaoman Xing; Turgut Durduran; Arjun G Yodh; Sydney M Evans; Cameron J Koch; Stephen M Hahn; Harry Quon; Chandra M Sehgal; William M F Lee; Amit Maity
Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy.
PloS one 2009;4(8):e6539.
2008: Sydney M Evans; Kevin W Jenkins; W Timothy Jenkins; Thomas Dilling; Kevin D Judy; Amy Schrlau; Alexander R Judkins; Stephen M Hahn; Cameron J Koch
Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors.
Radiation research 2008;170(6):677-90.
2008: Iraimoudi S Ayene; John E Biaglow; Alexander V Kachur; Thomas D Stamato; Cameron J Koch
Mutation in G6PD gene leads to loss of cellular control of protein glutathionylation: mechanism and implication.
Journal of cellular biochemistry 2008;103(1):123-35.
2007: Stephen W Tuttle; Amit Maity; Patricia R Oprysko; Alexander V Kachur; Iraimoudi S Ayene; John E Biaglow; Cameron J Koch
Detection of reactive oxygen species via endogenous oxidative pentose phosphate cycle activity in response to oxygen concentration: implications for the mechanism of HIF-1alpha stabilization under moderate hypoxia.
The Journal of biological chemistry 2007;282(51):36790-6.
2007: Sydney Evans; Kevin L Du; Ara A Chalian; Rosemarie Mick; Paul J Zhang; Stephen M Hahn; Harry Quon; Robert Lustig; Gregory S Weinstein; Cameron J Koch
Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome.
International journal of radiation oncology, biology, physics 2007;69(4):1024-31.
2007: Hsing-Wen Wang; Jarod C Finlay; Kijoon Lee; Timothy C Zhu; Mary E Putt; Eli Glatstein; Cameron J Koch; Sydney Evans; Stephen M Hahn; Theresa M Busch; Arjun G Yodh
Quantitative comparison of tissue oxygen and motexafin lutetium uptake by ex vivo and noninvasive in vivo techniques in patients with intraperitoneal carcinomatosis.
Journal of biomedical optics 2007;12(3):034023.
2007: Donald T T Yapp; Janet Woo; Aileen Kartono; Jonathan Sy; Thomas Oliver; Kirsten Skov; Cameron J Koch; Hans Adomat; Wieslawa H Dragowska; Ladan Fazli; Ladan Fadzli; Thomas J Ruth; Michael J Adam; David Green; Martin Gleave
Non-invasive evaluation of tumour hypoxia in the Shionogi tumour model for prostate cancer with 18F-EF5 and positron emission tomography.
BJU international 2007;99(5):1154-60.
2007: Iraimoudi S Ayene; Cameron J Koch; Robert E Krisch
DNA strand breakage by bivalent metal ions and ionizing radiation.
International journal of radiation biology 2007;83(3):195-210.
2006: Sydney Evans; Amy E Schrlau; Ara A Chalian; Paul Zhang; Cameron J Koch
Oxygen levels in normal and previously irradiated human skin as assessed by EF5 binding.
The Journal of investigative dermatology 2006;126(12):2596-606.
2006: N Pore; Anjali K Gupta; george cerniglia; Zibin Jiang; Eric J Bernhard; Sydney Evans; Cameron J Koch; Stephen M Hahn; Amit Maity
Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and increases tumor oxygenation: implications for radiotherapy.
Cancer research 2006;66(18):9252-9.
2006: John E Biaglow; Iraimoudi S Ayene; Stephen W Tuttle; Cameron J Koch; Jeremiah Donahue; John J Mieyal
Role of vicinal protein thiols in radiation and cytotoxic responses.
Radiation research 2006;165(3):307-17.
2006: Sydney Evans; Douglas L Fraker; Stephen M Hahn; Kristen Gleason; W Timothy Jenkins; Kevin Jenkins; Wei-Ting Hwang; Paul Zhang; Rosemarie Mick; Cameron J Koch
EF5 binding and clinical outcome in human soft tissue sarcomas.
International journal of radiation oncology, biology, physics 2006;64(3):922-7.
2005: Yuquan Shi; Caroline S Lee; Junmin Wu; Cameron J Koch; Stephen R Thom; Amit Maity; Eric J Bernhard
Effects of hyperbaric oxygen exposure on experimental head and neck tumor growth, oxygenation, and vasculature.
Head & neck 2005;27(5):362-9.
2005: Iraimoudi S Ayene; Lance P Ford; Cameron J Koch
Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation.
Molecular cancer therapeutics 2005;4(4):529-36.
2005: Yuquan Shi; Junmin Wu; Rosemarie Mick; george cerniglia; Elizabeth Cohen-Jonathan; Johng S Rhim; Cameron J Koch; Eric J Bernhard
Farnesyltransferase inhibitor effects on prostate tumor micro-environment and radiation survival.
The Prostate 2005;62(1):69-82.
2004: Sydney Evans; Kevin D Judy; Isolde Dunphy; W Timothy Jenkins; Wei-Ting Hwang; PETER NELSON; Robert Lustig; Kevin Jenkins; Deirdre P Magarelli; Stephen M Hahn; Ruth A Collins; M Sean Grady; Cameron J Koch
Hypoxia is important in the biology and aggression of human glial brain tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8177-84.
2004: Kirsten Skov; Hans Adomat; Mary Bowden; Wieslawa H Dragowska; Martin Gleave; Cameron J Koch; Janet Woo; Donald T T Yapp
Hypoxia in the androgen-dependent Shionogi model for prostate cancer at three stages.
Radiation research 2004;162(5):547-53.
2004: Geza Acs; Mei Chen; Xiaowei Xu; Peter Acs; Ajay Verma; Cameron J Koch
Autocrine erythropoietin signaling inhibits hypoxia-induced apoptosis in human breast carcinoma cells.
Cancer letters 2004;214(2):243-51.
2004: Theresa M Busch; Stephen M Hahn; E Paul Wileyto; Cameron J Koch; Douglas L Fraker; Paul Zhang; Mary E Putt; Kristen Gleason; Daniel B Shin; Michael J Emanuele; Kevin Jenkins; Eli Glatstein; Sydney Evans
Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4630-8.
2004: Yi Pan; Patricia R Oprysko; Andrew M Asham; Cameron J Koch; Marie Celeste Simon
p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment.
Oncogene 2004;23(29):4975-83.
2004: Sydney Evans; Kevin D Judy; Isolde Dunphy; W Timothy Jenkins; PETER NELSON; Ruth Collins; E Paul Wileyto; Kevin Jenkins; Stephen M Hahn; Craig W Stevens; Alexander R Judkins; Peter Phillips; Birgit Geoerger; Cameron J Koch
Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding.
Cancer research 2004;64(5):1886-92.
2003: Sydney Evans; Cameron J Koch
Prognostic significance of tumor oxygenation in humans.
Cancer letters 2003;195(1):1-16.
2003: John E Biaglow; Iraimoudi S Ayene; Cameron J Koch; Jeremiah Donahue; Thomas D Stamato; John J Mieyal; Stephen W Tuttle
Radiation response of cells during altered protein thiol redox.
Radiation research 2003;159(4):484-94.
2003: Lisa S Ziemer; Sydney Evans; Alexander V Kachur; A Lee Shuman; Christopher A Cardi; W Timothy Jenkins; Joel S Karp; Abass Alavi; William R Dolbier; Cameron J Koch
Noninvasive imaging of tumor hypoxia in rats using the 2-nitroimidazole 18F-EF5.
European journal of nuclear medicine and molecular imaging 2003;30(2):259-66.
2003: Cameron J Koch; Sydney Evans
Non-invasive PET and SPECT imaging of tissue hypoxia using isotopically labeled 2-nitroimidazoles.
Advances in experimental medicine and biology 2003;510():285-92.
2003: Cameron J Koch
Oxygen sensor design: analysis and correction of problems associated with zero current, stability and structure.
Advances in experimental medicine and biology 2003;510():151-6.
2003: Theresa M Busch; E Paul Wileyto; Sydney Evans; Cameron J Koch
Quantitative spatial analysis of hypoxia and vascular perfusion in tumor sections.
Advances in experimental medicine and biology 2003;510():37-43.
2002: Theresa M Busch; E Paul Wileyto; Michael J Emanuele; Fabio Del Piero; Laura Marconato; Eli Glatstein; Cameron J Koch
Photodynamic therapy creates fluence rate-dependent gradients in the intratumoral spatial distribution of oxygen.
Cancer research 2002;62(24):7273-9.
2002: Cameron J Koch; Patricia R Oprysko; A Lee Shuman; W Timothy Jenkins; Gordon Brandt; Sydney Evans
Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion.
Cancer research 2002;62(13):3626-9.
2002: L Nadal-Desbarats; harish poptani; Patricia R Oprysko; W Timothy Jenkins; Theresa M Busch; David S Nelson; Jerry D Glickson; Cameron J Koch; Sydney Evans
Effects of hyperglycemia on oxygenation, radiosensitivity and bioenergetic status of subcutaneous RIF-1 tumors.
International journal of oncology 2002;21(1):103-10.
2002: Iraimoudi S Ayene; Thomas D Stamato; Stanley K Mauldin; John E Biaglow; Stephen W Tuttle; Susan F Jenkins; Cameron J Koch
Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress.
The Journal of biological chemistry 2002;277(12):9929-35.
2002: Cameron J Koch
Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5.
Methods in enzymology 2002;352():3-31.
2001: Lisa S Ziemer; Cameron J Koch; Amit Maity; Deirdre P Magarelli; A M Horan; Sydney Evans
Hypoxia and VEGF mRNA expression in human tumors.
Neoplasia (New York, N.Y.) 2001;3(6):500-8.
2001: Sydney Evans; Stephen M Hahn; Deirdre P Magarelli; Cameron J Koch
Hypoxic heterogeneity in human tumors: EF5 binding, vasculature, necrosis, and proliferation.
American journal of clinical oncology 2001;24(5):467-72.
2001: Annamarie D Horan; Cameron J Koch
The K(m) for Radiosensitization of Human Tumor Cells by Oxygen is Much Greater than 3 mmHg and is Further Increased by Elevated Levels of Cysteine.
Radiation research 2001;156(4):388-98.
2001: Cameron J Koch; Stephen M Hahn; Kenneth Rockwell; J M Covey; W Gillies McKenna; Sydney Evans
Pharmacokinetics of EF5 [2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide] in human patients: implications for hypoxia measurements in vivo by 2-nitroimidazoles.
Cancer chemotherapy and pharmacology 2001;48(3):177-87.
2001: Amit Maity; W Sall; Cameron J Koch; Patricia R Oprysko; Sydney Evans
Low pO2 and beta-estradiol induce VEGF in MCF-7 and MCF-7-5C cells: relationship to in vivo hypoxia.
Breast cancer research and treatment 2001;67(1):51-60.
2001: Elizabeth Cohen-Jonathan; Sydney Evans; Cameron J Koch; Ruth J Muschel; W Gillies McKenna; Junmin Wu; Eric J Bernhard
The farnesyltransferase inhibitor L744,832 reduces hypoxia in tumors expressing activated H-ras.
Cancer research 2001;61(5):2289-93.
2001: Sydney Evans; Stephen M Hahn; Deirdre P Magarelli; Paul J Zhang; W Timothy Jenkins; Douglas L Fraker; R Alex Hsi; W Gillies McKenna; Cameron J Koch
Hypoxia in human intraperitoneal and extremity sarcomas.
International journal of radiation oncology, biology, physics 2001;49(2):587-96.
2001: William R Dolbier; A R Li; Cameron J Koch; Chyng-Yann Shiue; Alexander V Kachur
[18F]-EF5, a marker for PET detection of hypoxia: synthesis of precursor and a new fluorination procedure.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2001;54(1):73-80.
2000: Iraimoudi S Ayene; Cameron J Koch; Stephen W Tuttle; Thomas D Stamato; ML Perez; John E Biaglow
Oxidation of cellular thiols by hydroxyethyldisulphide inhibits DNA double-strand-break rejoining in G6PD deficient mammalian cells.
International journal of radiation biology 2000;76(11):1523-31.
2000: John E Biaglow; Iraimoudi S Ayene; Cameron J Koch; Jeremiah Donahue; Thomas D Stamato; Stephen W Tuttle
G6PD deficient cells and the bioreduction of disulfides: effects of DHEA, GSH depletion and phenylarsine oxide.
Biochemical and biophysical research communications 2000;273(3):846-52.
2000: Theresa M Busch; Stephen M Hahn; Sydney Evans; Cameron J Koch
Depletion of tumor oxygenation during photodynamic therapy: detection by the hypoxia marker EF3 [2-(2-nitroimidazol-1[H]-yl)-N-(3,3,3-trifluoropropyl)acetamide ].
Cancer research 2000;60(10):2636-42.
2000: Sydney Evans; S Hahn; D R Pook; W Timothy Jenkins; Ara A Chalian; Paul Zhang; C Stevens; R Weber; Gregory Weinstein; I Benjamin; Natasha Mirza; M Morgan; S Rubin; W Gillies McKenna; EM Lord; Cameron J Koch
Detection of hypoxia in human squamous cell carcinoma by EF5 binding.
Cancer research 2000;60(7):2018-24.
2000: Iraimoudi S Ayene; Eric J Bernhard; W Gillies McKenna; Ruth J Muschel; Robert E Krisch; Cameron J Koch
DNA as an important target in radiation-induced apoptosis of MYC and MYC plus RAS transfected rat embryo fibroblasts.
International journal of radiation biology 2000;76(3):343-54.
2000: W Timothy Jenkins; Sydney Evans; Cameron J Koch
Hypoxia and necrosis in rat 9L glioma and Morris 7777 hepatoma tumors: comparative measurements using EF5 binding and the Eppendorf needle electrode.
International journal of radiation oncology, biology, physics 2000;46(4):1005-17.
2000: J Lee; James P Moran; Bruce M Fenton; Cameron J Koch; john frelinger; P C Keng; Edith M Lord
Alteration of tumour response to radiation by interleukin-2 gene transfer.
British journal of cancer 2000;82(4):937-44.
2000: Sydney Evans; Alexander V Kachur; Chyng-Yann Shiue; Roland Hustinx; W Timothy Jenkins; G G Shive; Joel S Karp; Abass Alavi; EM Lord; William R Dolbier; Cameron J Koch
Noninvasive detection of tumor hypoxia using the 2-nitroimidazole [18F]EF1.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(2):327-36.
2000: David F Wilson; Sydney Evans; Charmaine Rozanov; Arijit Roy; Cameron J Koch; KM Laughlin; Sukhamay Lahiri
Intracellular PO2 of the carotid body.
Advances in experimental medicine and biology 2000;475():637-44.
1999: Alexander V Kachur; William R Dolbier; Sydney Evans; Chyng-Yann Shiue; Grace G Shiue; Kirsten Skov; I R Baird; B R James; A R Li; A Roche; Cameron J Koch
Synthesis of new hypoxia markers EF1 and [18F]-EF1.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1999;51(6):643-50.
1999: Michael S Gee; Cameron J Koch; Sydney Evans; W Timothy Jenkins; C Hank Pletcher; Jonni S Moore; H K Koblish; J Lee; EM Lord; Giorgio Trinchieri; William M F Lee
Hypoxia-mediated apoptosis from angiogenesis inhibition underlies tumor control by recombinant interleukin 12.
Cancer research 1999;59(19):4882-9.
1999: Annamarie D Horan; AR Giandomenico; Cameron J Koch
Effect of oxygen on radiation-induced DNA damage in isolated nuclei.
Radiation research 1999;152(2):144-53.
1999: Alexander V Kachur; Cameron J Koch; John E Biaglow
Mechanism of copper-catalyzed autoxidation of cysteine.
Free radical research 1999;31(1):23-34.
1999: Bruce M Fenton; Scott F Paoni; J Lee; Cameron J Koch; Edith M Lord
Quantification of tumour vasculature and hypoxia by immunohistochemical staining and HbO2 saturation measurements.
British journal of cancer 1999;79(3-4):464-71.
1999: M Bergeron; Sydney Evans; Frank R Sharp; Cameron J Koch; E M Lord; Donna M Ferriero
Detection of hypoxic cells with the 2-nitroimidazole, EF5, correlates with early redox changes in rat brain after perinatal hypoxia-ischemia.
Neuroscience 1999;89(4):1357-66.
1998: Stephen W Tuttle; A M Horan; Cameron J Koch; Kathryn D Held; Yefim Manevich; John E Biaglow
Radiation-sensitive tyrosine phosphorylation of cellular proteins: sensitive to changes in GSH content induced by pretreatment with N-acetyl-L-cysteine or L-buthionine-S,R-sulfoximine.
International journal of radiation oncology, biology, physics 1998;42(4):833-8.
1998: John E Biaglow; Cameron J Koch; Stephen W Tuttle; Yefim Manevich; Iraimoudi S Ayene; Eric J Bernhard; W Gillies McKenna; Alexander V Kachur
The measurement of bioreductive capacity of tumor cells using methylene blue.
International journal of radiation oncology, biology, physics 1998;42(4):769-73.
1998: A Schwentker; Sydney Evans; M Partington; B L Johnson; Cameron J Koch; Stephen R Thom
A model of wound healing in chronically radiation-damaged rat skin.
Cancer letters 1998;128(1):71-8.
1998: J Lee; Bruce M Fenton; Cameron J Koch; john frelinger; Edith M Lord
Interleukin 2 expression by tumor cells alters both the immune response and the tumor microenvironment.
Cancer research 1998;58(7):1478-85.
1998: Alexander V Kachur; Cameron J Koch; John E Biaglow
Mechanism of copper-catalyzed oxidation of glutathione.
Free radical research 1998;28(3):259-69.
1998: Bruce M Fenton; Scott F Paoni; Cameron J Koch; Edith M Lord
Effect of local irradiation on tumor oxygenation, perfused vessel density, and development of hypoxia.
Advances in experimental medicine and biology 1998;454():619-28.
1998: Cameron J Koch; J E Chasan; W Timothy Jenkins; C Y Chan; KM Laughlin; Sydney Evans
Co-localization of hypoxia and apoptosis in irradiated and untreated HCT116 human colon carcinoma xenografts.
Advances in experimental medicine and biology 1998;454():611-8.
1998: David F Wilson; KM Laughlin; Charmaine Rozanov; Anil Mokashi; Sergei A Vinogradov; Sukhamay Lahiri; Cameron J Koch; Sydney Evans
Tissue oxygen sensing and the carotid body.
Advances in experimental medicine and biology 1998;454():447-54.
1998: Craig W Stevens; george cerniglia; AR Giandomenico; Cameron J Koch
DNA damaging agents improve stable gene transfer efficiency in mammalian cells.
Radiation oncology investigations 1998;6(1):1-9.
1997: Sydney Evans; Cameron J Koch; KM Laughlin; W Timothy Jenkins; Thomas J Van Winkle; David F Wilson
Tamoxifen induces hypoxia in MCF-7 xenografts.
Cancer research 1997;57(22):5155-61.
1997: Annamarie D Horan; C Y Chan; C Hank Pletcher; Chandrakala Menon; Sydney Evans; Jonni S Moore; Cameron J Koch
Analysis of tumor thiol concentrations: comparison of flow cytometric with chemical and biochemical techniques.
Cytometry 1997;29(1):76-82.
1997: Irving M Shapiro; Kyle D Mansfield; Sydney Evans; EM Lord; Cameron J Koch
Chondrocytes in the endochondral growth cartilage are not hypoxic.
The American journal of physiology 1997;272(4 Pt 1):C1134-43.
1997: Alexander V Kachur; Kathryn D Held; Cameron J Koch; John E Biaglow
Mechanism of production of hydroxyl radicals in the copper-catalyzed oxidation of dithiothreitol.
Radiation research 1997;147(4):409-15.
1997: Leu-Wei Lo; Sergei A Vinogradov; Cameron J Koch; David F Wilson
A new, water soluble, phosphor for oxygen measurements in vivo.
Advances in experimental medicine and biology 1997;428():651-6.
1997: Sydney Evans; M Bergeron; Donna M Ferriero; Frank R Sharp; H Hermeking; Richard N Kitsis; David L Geenen; S Bialik; EM Lord; Cameron J Koch
Imaging hypoxia in diseased tissues.
Advances in experimental medicine and biology 1997;428():595-603.
1997: Sydney Evans; W Timothy Jenkins; M Shapiro; Cameron J Koch
Evaluation of the concept of "hypoxic fraction" as a descriptor of tumor oxygenation status.
Advances in experimental medicine and biology 1997;411():215-25.
1997: AR Giandomenico; G E Cerniglia; John E Biaglow; Craig W Stevens; Cameron J Koch
The importance of sodium pyruvate in assessing damage produced by hydrogen peroxide.
Free radical biology & medicine 1997;23(3):426-34.
1996: Iraimoudi S Ayene; Cameron J Koch; R E Krisch
Simulation of the cellular oxygen effect with an SV40 DNA model system using DNA strand breaks as an end point.
Radiation research 1996;146(5):501-9.
1996: Cameron J Koch; Sydney Evans
Cysteine concentrations in rodent tumors: unexpectedly high values may cause therapy resistance.
International journal of cancer. Journal international du cancer 1996;67(5):661-7.
1996: Ramesh Rajpurohit; Cameron J Koch; Z Tao; C M Teixeira; Irving M Shapiro
Adaptation of chondrocytes to low oxygen tension: relationship between hypoxia and cellular metabolism.
Journal of cellular physiology 1996;168(2):424-32.
1996: J Lee; Dietmar W Siemann; Cameron J Koch; E M Lord
Direct relationship between radiobiological hypoxia in tumors and monoclonal antibody detection of EF5 cellular adducts.
International journal of cancer. Journal international du cancer 1996;67(3):372-8.
1996: KM Laughlin; Sydney Evans; W Timothy Jenkins; M Tracy; C Y Chan; E M Lord; Cameron J Koch
Biodistribution of the nitroimidazole EF5 (2-[2-nitro-1H-imidazol-1-yl]-N-(2,2,3,3,3-pentafluoropropyl) acetamide) in mice bearing subcutaneous EMT6 tumors.
The Journal of pharmacology and experimental therapeutics 1996;277(2):1049-57.
1996: Leu-Wei Lo; Cameron J Koch; David F Wilson
Calibration of oxygen-dependent quenching of the phosphorescence of Pd-meso-tetra (4-carboxyphenyl) porphine: a phosphor with general application for measuring oxygen concentration in biological systems.
Analytical biochemistry 1996;236(1):153-60.
1996: Sydney Evans; W Timothy Jenkins; B Joiner; E M Lord; Cameron J Koch
2-Nitroimidazole (EF5) binding predicts radiation resistance in individual 9L s.c. tumors.
Cancer research 1996;56(2):405-11.
1996: M L Woods; Cameron J Koch; E M Lord
Detection of individual hypoxic cells in multicellular spheroids by flow cytometry using the 2-nitroimidazole, EF5, and monoclonal antibodies.
International journal of radiation oncology, biology, physics 1996;34(1):93-101.
1995: Iraimoudi S Ayene; Cameron J Koch; R E Krisch
Modification of radiation-induced strand breaks by glutathione: comparison of single- and double-strand breaks in SV40 DNA.
Radiation research 1995;144(1):1-8.
1995: Sydney Evans; B Joiner; W Timothy Jenkins; KM Laughlin; E M Lord; Cameron J Koch
Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide].
British journal of cancer 1995;72(4):875-82.
1995: Cameron J Koch; Sydney Evans; E M Lord
Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)a cet amide] : analysis of drug adducts by fluorescent antibodies vs bound radioactivity.
British journal of cancer 1995;72(4):869-74.
1995: Iraimoudi S Ayene; Cameron J Koch; R E Krisch
Role of scavenger-derived radicals in the induction of double-strand and single-strand breaks in irradiated DNA.
Radiation research 1995;142(2):133-43.
1995: Ruth J Muschel; Eric J Bernhard; Luis Garza; W Gillies McKenna; Cameron J Koch
Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling.
Cancer research 1995;55(5):995-8.
1994: Cameron J Koch; A R Giandomenico
The alkaline elution technique for measuring DNA single strand breaks: increased reliability and sensitivity.
Analytical biochemistry 1994;220(1):58-65.
1994: Stephen W Tuttle; L Hazard; Cameron J Koch; James B Mitchell; C Norman Coleman; John E Biaglow
Bioreductive metabolism of SR-4233 (WIN 59075) by whole cell suspensions under aerobic and hypoxic conditions: role of the pentose cycle and implications for the mechanism of cytotoxicity observed in air.
International journal of radiation oncology, biology, physics 1994;29(2):357-62.
1994: Cameron J Koch; Kirsten Skov
Enhanced radiation-sensitivity by preincubation with nitroimidazoles: effect of glutathione depletion.
International journal of radiation oncology, biology, physics 1994;29(2):345-9.
1994: Cameron J Koch; A R Giandomenico
Do low doses of radiation induce a response modulating induction or repair of DNA single-strand breaks?
Radiation research 1994;138(1 Suppl):S89-92.
1993: Cameron J Koch; A R Giandomenico; C W Iyengar
Bioreductive metabolism of AF-2[2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide] combined with 2-nitroimidazoles. Implications for use as hypoxic cell markers.
Biochemical pharmacology 1993;46(6):1029-36.
1993: Cameron J Koch
Unusual oxygen concentration dependence of toxicity of SR-4233, a hypoxic cell toxin.
Cancer research 1993;53(17):3992-7.
1992: Cameron J Koch; Kirsten Skov
Comparisons of cellular radiation response using absolute rather than relative parameters.
Radiation research 1992;132(1):40-9.
1991: Cameron J Koch; James Raleigh
Radiolytic reduction of protein and nonprotein disulfides in the presence of formate: a chain reaction.
Archives of biochemistry and biophysics 1991;287(1):75-84.
1989: Cameron J Koch; C C Stobbe; P Hettiaratchi
Combined radiation-protective and radiation-sensitizing agents. IV: Measurement of intracellular protector concentrations.
International journal of radiation oncology, biology, physics 1989;16(4):1025-7.
1987: D J Van Os-Corby; Cameron J Koch; J Donald Chapman
Is misonidazole binding to mouse tissues a measure of cellular pO2?
Biochemical pharmacology 1987;36(20):3487-94.
1986: Cameron J Koch; C C Stobbe; K A Baer
Combined radiation-protective and radiation-sensitizing agents. III: Radiosensitization by misonidazole as a function of concentrations of endogenous glutathione or exogenous thiols.
International journal of radiation oncology, biology, physics 1986;12(7):1151-5.
1984: Cameron J Koch; C C Stobbe; K A Baer
Metabolism induced binding of 14C-misonidazole to hypoxic cells: kinetic dependence on oxygen concentration and misonidazole concentration.
International journal of radiation oncology, biology, physics 1984;10(8):1327-31.
1984: Cameron J Koch; C C Stobbe; E A Bump
The effect on the Km for radiosensitization at 0 degree C of thiol depletion by diethylmaleate pretreatment: quantitative differences found using the radiation sensitizing agent misonidazole or oxygen.
Radiation research 1984;98(1):141-53.