FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Patrick Kochanek

Research Profile

Disorders

Living Beings

Procedures

Anatomy

Physiology

Cerebrovascular Circulation

Concepts & Ideas

Co-author Network

Publications

TOP 3
Michael J Bell; Patrick M Kochanek
Pediatric traumatic brain injury in 2012: the year with new guidelines and common data elements.
Brian Blasiole; Amin Cheikhi; Keri L Janesko-Feldman; Valerian Kagan; James Atkins; Hülya Bayr; Joseph B Long; Vincent A Vagni; Stephen R Wisniewski; Patrick M Kochanek
Effect of hyperoxia on resuscitation of experimental combined traumatic brain injury and hemorrhagic shock in mice.
Patrick M Kochanek; C Edward Dixon; Ericka L Fink; Alicia K Au; Hülya Bayır; Michael J Bell; Rachel Pardes Berger; Robert S B Clark
The potential for bio-mediators and biomarkers in pediatric traumatic brain injury and neurocritical care.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Patrick Kochanek (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Michael J Bell; Patrick M Kochanek
Pediatric traumatic brain injury in 2012: the year with new guidelines and common data elements.
Critical care clinics 2013;29(2):223-38.
2013: Brian Blasiole; Amin Cheikhi; Keri L Janesko-Feldman; Valerian Kagan; James Atkins; Hülya Bayr; Joseph B Long; Vincent A Vagni; Stephen R Wisniewski; Patrick M Kochanek
Effect of hyperoxia on resuscitation of experimental combined traumatic brain injury and hemorrhagic shock in mice.
Anesthesiology 2013;118(3):649-63.
2013: Patrick M Kochanek; C Edward Dixon; Ericka L Fink; Alicia K Au; Hülya Bayır; Michael J Bell; Rachel Pardes Berger; Robert S B Clark
The potential for bio-mediators and biomarkers in pediatric traumatic brain injury and neurocritical care.
Frontiers in neurology 2013;4():40.
2013: Travis C Jackson; J D Verrier; Patrick M Kochanek
Anthraquinone-2-sulfonic acid (AQ2S) is a novel neurotherapeutic agent.
Cell death & disease 2013;4():e451.
2013: Lesley M Foley; Chien Ho; Alia M Iqbal O'Meara; Larry W Jenkins; T Kevin Hitchens; John A Melick; Stephen R Wisniewski; Patrick M Kochanek
MRI assessment of cerebral blood flow after experimental traumatic brain injury combined with hemorrhagic shock in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013;33(1):129-36.
2012: Tomas Drabek; Patrick M Kochanek
Therapeutic Hypothermia on Its 10th Anniversary: Is it Time to Turn the Thermostat Down?
Circulation 2012;126(24):2803-5.
2012: Patrick M Kochanek; Hülya Bayır
Optimizing oxygenation and ventilation after cardiac arrest in "little adults".
Resuscitation 2012;83(12):1425-6.
2012: E Su; Elizabeth C Tyler-Kabara; Stephen R Wisniewski; H Bayir; P David Adelson; Michael J Bell; Robert S B Clark; Keri L Janesko-Feldman; Patrick M Kochanek; Rachel Pardes Berger
Increased CSF concentrations of myelin basic protein after TBI in infants and children: absence of significant effect of therapeutic hypothermia.
Neurocritical care 2012;17(3):401-7.
2012: Steven L Shein; Erik Su; Michael J Bell; Patrick M Kochanek; Jennifer Exo
Intracranial monitoring and continuous data collection.
Critical care medicine 2012;40(11):3115-6; author reply 3116.
2012: Jing Ji; Valerian E Kagan; Anthony E Kline; Patrick M Kochanek; Mioara D Manole; David O Okonkwo; Ava M Puccio; Alejandro K Samhan-Arias; Louis J Sparvero; Vladimir A Tyurin; Yulia Y Tyurina; Peter Wipf; Henry Alexander; Andrew A Amoscato; Jeffrey P Cheng; Robert S B Clark; Bruno Fink; Hülya Bayır
Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury.
Nature neuroscience 2012;15(10):1407-13.
2012: Edwin K Jackson; Keri Janesko-Feldman; Zaichuan Mi; Jonathan D Verrier; Dongmei Cheng; Patrick M Kochanek
Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney.
American journal of physiology. Renal physiology 2012;303(7):F1000-5.
2012: Steven L Shein; Elizabeth C Tyler-Kabara; Stephen R Wisniewski; Michael J Bell; Kenneth Feldman; Patrick M Kochanek; Kathi Makoroff; Philip V Scribano; Rachel Pardes Berger
Risk factors for mortality in children with abusive head trauma.
The Journal of pediatrics 2012;161(4):716-722.e1.
2012: Joseph N Hemerka; Keri L Janesko-Feldman; Larry W Jenkins; Hülya Bayır; Brian Blasiole; Robert S B Clark; C Edward Dixon; Jennifer L Exo; Robert H Garman; David K Shellington; Samuel A Tisherman; Vincent A Vagni; Stephen R Wisniewski; Xianren Wu; Mu Xu; Patrick M Kochanek
Severe brief pressure-controlled hemorrhagic shock after traumatic brain injury exacerbates functional deficits and long-term neuropathological damage in mice.
Journal of neurotrauma 2012;29(12):2192-208.
2012: Louis J Sparvero; Hülya Bayir; Andrew A Amoscato; C Edward Dixon; Patrick M Kochanek; Joseph B Long; Bruce R Pitt; Valerian E Kagan
Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations.
Chemistry and physics of lipids 2012;165(5):545-62.
2012: Jonathan D Verrier; Rashmi Bansal; Travis C Jackson; Patrick M Kochanek; David O Okonkwo; Ava M Puccio; Edwin K Jackson
The brain in vivo expresses the 2',3'-cAMP-adenosine pathway.
Journal of neurochemistry 2012;122(1):115-25.
2012: Rosanne Salonia; Patrick M Kochanek; Michael J Bell; Rachel Pardes Berger
The utility of near infrared spectroscopy in detecting intracranial hemorrhage in children.
Journal of neurotrauma 2012;29(6):1047-53.
2012: Michael Shoykhet; Daniel J Simons; Henry Alexander; Christina Hosler; Patrick M Kochanek; Robert S B Clark
Thalamocortical dysfunction and thalamic injury after asphyxial cardiac arrest in developing rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(14):4972-81.
2012: Philip E Empey; Patrick M Kochanek; John A Melick; Tricia M Miller; Ashley H Philbrick; Samuel M Poloyac
Mild hypothermia decreases fentanyl and midazolam steady-state clearance in a rat model of cardiac arrest.
Critical care medicine 2012;40(4):1221-8.
2012: Tomas Drabek; Brad End; Edwin K Jackson; Andreas Janata; Keri L Janesko-Feldman; Jason Stezoski; Samuel A Tisherman; Vincent A Vagni; Nico van Rooijen; Caleb D Wilson; Patrick M Kochanek
Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats.
Resuscitation 2012;83(4):517-26.
2012: Jing Ji; Valerian E Kagan; Patrick M Kochanek; David F Meaney; Donna B Stolz; Minke Tang; Yulia Y Tyurina; Robert S B Clark; Weihong Feng; Hülya Bayır
Mitochondrial injury after mechanical stretch of cortical neurons in vitro: biomarkers of apoptosis and selective peroxidation of anionic phospholipids.
Journal of neurotrauma 2012;29(5):776-88.
2012: Mioara D Manole; Henry Alexander; Hülya Bayır; Lesley M Foley; Robert Garman; T Kevin Hitchens; Chien Ho; Carleton J C Hsia; Patrick M Kochanek; Li Ma; Robert S B Clark
Polynitroxyl albumin and albumin therapy after pediatric asphyxial cardiac arrest: effects on cerebral blood flow and neurologic outcome.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(3):560-9.
2011: Patrick M Kochanek
Mass critical care for children: implications for adult critical care.
Critical care medicine 2011;39(12):2783.
2011: Jiangquan Zhou; Robert R Bies; Philip E Empey; Patrick M Kochanek; Samuel M Poloyac
Cardiac arrest and therapeutic hypothermia decrease isoform-specific cytochrome P450 drug metabolism.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(12):2209-18.
2011: Mioara D Manole; Patrick M Kochanek; Robert S Clark
"Lost in translation?" Noninvasive cerebral monitoring after cardiac arrest.
Critical care medicine 2011;39(10):2379-80.
2011: Natalia A Belikova; Amin Cheikhi; Ashley L Glumac; Valerian E Kagan; Valentyna Kapralova; Patrick M Kochanek; Yulia Y Tyurina; Vincent A Vagni; Hülya Bayir
A high-throughput screening assay of ascorbate in brain samples.
Journal of neuroscience methods 2011;201(1):185-90.
2011: Amy K Wagner; Krutika B Amin; Hülya Bayir; Robert S B Clark; C Edward Dixon; Patrick M Kochanek; Emily H McCullough; Christian Niyonkuru; H Ozawa; Brett A Postal; Anthony Fabio
CSF Bcl-2 and cytochrome C temporal profiles in outcome prediction for adults with severe TBI.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(9):1886-96.
2011: Patrick M Kochanek; John Povlishock; Frank C Tortella; Helen M Bramlett; W Dalton Dietrich; C Edward Dixon; Ronald L Hayes; Kevin K W Wang
A novel multicenter preclinical drug screening and biomarker consortium for experimental traumatic brain injury: operation brain trauma therapy.
The Journal of trauma 2011;71(1 Suppl):S15-24.
2011: Craig M Smith; Yaming Chen; Mara L Sullivan; Patrick M Kochanek; Robert S B Clark
Autophagy in acute brain injury: feast, famine, or folly?
Neurobiology of disease 2011;43(1):52-9.
2011: Robert H Garman; Edwin K Jackson; Larry W Jenkins; Valerian Kagan; Steven A Parks; David V Ritzel; Peter V Swauger; Robert C Switzer; Lawrence C Tong; Hülya Bayir; Richard A Bauman; Robert S B Clark; C Edward Dixon; Patrick M Kochanek
Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury.
Journal of neurotrauma 2011;28(6):947-59.
2011: David K Shellington; Lina Du; Xianren Wu; Jennifer Exo; Vincent A Vagni; Li Ma; Keri L Janesko-Feldman; Robert S B Clark; Hülya Bayir; C Edward Dixon; Larry W Jenkins; Carleton J C Hsia; Patrick M Kochanek
Polynitroxylated pegylated hemoglobin: a novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and hemorrhagic hypotension in mice.
Critical care medicine 2011;39(3):494-505.
2011: Karen H Walson; Minke Tang; Ashley Glumac; Henry Alexander; Mioara D Manole; Li Ma; Carleton J C Hsia; Robert S B Clark; Patrick M Kochanek; Valerian E Kagan; Hülya Bayr
Normoxic versus hyperoxic resuscitation in pediatric asphyxial cardiac arrest: effects on oxidative stress.
Critical care medicine 2011;39(2):335-43.
2011: Tomas Drabek; Patrick M Kochanek; Jason Stezoski; Xianren Wu; Hülya Bayir; Ryan C Morhard; S William Stezoski; Samuel A Tisherman
Intravenous hydrogen sulfide does not induce hypothermia or improve survival from hemorrhagic shock in pigs.
Shock (Augusta, Ga.) 2011;35(1):67-73.
2010: Louis J Sparvero; Andrew A Amoscato; Patrick M Kochanek; Bruce R Pitt; Valerian E Kagan; Hülya Bayir
Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury.
Journal of neurochemistry 2010;115(6):1322-36.
2010: Rosanne Salonia; Philip E Empey; Samuel M Poloyac; Stephen R Wisniewski; Megan Klamerus; H Ozawa; Amy K Wagner; Randall A Ruppel; Michael J Bell; Keri Feldman; P David Adelson; Robert S B Clark; Patrick M Kochanek
Endothelin-1 is increased in cerebrospinal fluid and associated with unfavorable outcomes in children after severe traumatic brain injury.
Journal of neurotrauma 2010;27(10):1819-25.
2010: Alicia K Au; Hülya Bayir; Patrick M Kochanek; Robert S B Clark
Evaluation of autophagy using mouse models of brain injury.
Biochimica et biophysica acta 2010;1802(10):918-23.
2010: Detcho Stoyanovsky; Alexandr Kapralov; Zhentai Huang; Akihiro Maeda; Anatoly Osipov; Carleton J C Hsia; Li Ma; Patrick M Kochanek; Hulya Bayr; Valerian E Kagan
Unusual peroxidase activity of polynitroxylated pegylated hemoglobin: Elimination of H(2)O(2) coupled with intramolecular oxidation of nitroxides.
Biochemical and biophysical research communications 2010;399(2):139-43.
2010: Amy K Wagner; Megan A Miller; Joelle Scanlon; Dianxu Ren; Patrick M Kochanek; Yvette P Conley
Adenosine A1 receptor gene variants associated with post-traumatic seizures after severe TBI.
Epilepsy research 2010;90(3):259-72.
2010: Erika E Tress; Patrick M Kochanek; Richard A Saladino; Mioara D Manole
Cardiac arrest in children.
Journal of emergencies, trauma, and shock 2010;3(3):267-72.
2010: Patrick M Kochanek; Hülya Bayir
Titrating oxygen during and after cardiopulmonary resuscitation.
JAMA : the journal of the American Medical Association 2010;303(21):2190-1.
2010: Ericka L Fink; Patrick M Kochanek; Robert S B Clark; Michael J Bell
How I cool children in neurocritical care.
Neurocritical care 2010;12(3):414-20.
2010: David Hostler; Jiangquan Zhou; Michael A Tortorici; Robert R Bies; Jon C Rittenberger; Philip E Empey; Patrick M Kochanek; Clifton W Callaway; Samuel M Poloyac
Mild hypothermia alters midazolam pharmacokinetics in normal healthy volunteers.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(5):781-8.
2010: M Lee Haselkorn; David K Shellington; Edwin K Jackson; Vincent A Vagni; Keri L Janesko-Feldman; Raghvendra K Dubey; Delbert G Gillespie; Dongmei Cheng; Michael J Bell; Larry W Jenkins; Gregg E Homanics; Jurgen Schnermann; Patrick M Kochanek
Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice.
Journal of neurotrauma 2010;27(5):901-10.
2010: Sirine A Baltagi; Michael Shoykhet; Kathryn Felmet; Patrick M Kochanek; Michael J Bell
Neurological sequelae of 2009 influenza A (H1N1) in children: a case series observed during a pandemic.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2010;11(2):179-84.
2010: Ajit A Sarnaik; Yvette P Conley; David O Okonkwo; Taura L Barr; Ericka L Fink; Csaba Szabó; Patrick M Kochanek; Robert S B Clark
Influence of PARP-1 polymorphisms in patients after traumatic brain injury.
Journal of neurotrauma 2010;27(3):465-71.
2010: Patrick M Kochanek; Michael J Bell; Hülya Bayır
Quo vadis 2010? - carpe diem: challenges and opportunities in pediatric traumatic brain injury.
Developmental neuroscience 2010;32(5-6):335-42.
2010: Erik Su; Michael J Bell; Stephen R Wisniewski; P David Adelson; Keri L Janesko-Feldman; Rosanne Salonia; Robert S B Clark; Patrick M Kochanek; Valerian E Kagan; Hülya Bayır
α-Synuclein levels are elevated in cerebrospinal fluid following traumatic brain injury in infants and children: the effect of therapeutic hypothermia.
Developmental neuroscience 2010;32(5-6):385-95.
2010: Amit Mehta; Patrick M Kochanek; Elizabeth Tyler-Kabara; P David Adelson; Stephen R Wisniewski; Rachel Pardes Berger; Maria D Sidoni; Rachelle L Bell; Robert S B Clark; Michael J Bell
Relationship of intracranial pressure and cerebral perfusion pressure with outcome in young children after severe traumatic brain injury.
Developmental neuroscience 2010;32(5-6):413-9.
2010: Rachel Pardes Berger; Michael C Bazaco; Amy K Wagner; Patrick M Kochanek; Anthony Fabio
Trajectory analysis of serum biomarker concentrations facilitates outcome prediction after pediatric traumatic and hypoxemic brain injury.
Developmental neuroscience 2010;32(5-6):396-405.
2010: Vladimir A Tyurin; Yulia Y Tyurina; Vladimir B Ritov; Andriy Lysytsya; Andrew A Amoscato; Patrick M Kochanek; Ronald Hamilton; Steven T DeKosky; Joel S Greenberger; Hülya Bayir; Valerian E Kagan
Oxidative lipidomics of apoptosis: quantitative assessment of phospholipid hydroperoxides in cells and tissues.
Methods in molecular biology (Clifton, N.J.) 2010;610():353-74.
2010: Ericka L Fink; Robert S B Clark; Patrick M Kochanek; Michael J Bell; R Scott Watson
A tertiary care center's experience with therapeutic hypothermia after pediatric cardiac arrest.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2010;11(1):66-74.
2010: Minke Tang; Henry Alexander; Robert S B Clark; Patrick M Kochanek; Valerian E Kagan; Hülya Bayir
Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrest.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(1):119-29.
2009: Mioara D Manole; Patrick M Kochanek; Ericka L Fink; Robert S B Clark
Postcardiac arrest syndrome: focus on the brain.
Current opinion in pediatrics 2009;21(6):745-50.
2009: Jennifer L Exo; David K Shellington; Hülya Bayir; Vincent A Vagni; Keri Janesco-Feldman; Lil Ma; Carleton J Hsia; Robert S B Clark; Larry W Jenkins; C Edward Dixon; Patrick M Kochanek
Resuscitation of traumatic brain injury and hemorrhagic shock with polynitroxylated albumin, hextend, hypertonic saline, and lactated Ringer's: Effects on acute hemodynamics, survival, and neuronal death in mice.
Journal of neurotrauma 2009;26(12):2403-8.
2009: Joan Sanchez de Toledo; P David Adelson; R Scott Watson; Barbara A Gaines; S Danielle Brown; Patrick M Kochanek; Stephen R Wisniewski; Ericka Fink; Hülya Bayir; Robert S B Clark; Michael J Bell
Relationship between increases in pancreatic enzymes and cerebral events in children after traumatic brain injury.
Neurocritical care 2009;11(3):322-9.
2009: Vladimir A Tyurin; Yulia Y Tyurina; Mi-Yeon Jung; Muhammad A Tungekar; Karla J Wasserloos; Hülya Bayir; Joel S Greenberger; Patrick M Kochanek; Anna A Shvedova; Bruce Pitt; Valerian E Kagan
Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(26):2863-72.
2009: Tomas Drabek; Samuel A Tisherman; Lauren Beuke; Jason Stezoski; Keri Janesko-Feldman; Manuella Lahoud-Rahme; Patrick M Kochanek
Deep hypothermia attenuates microglial proliferation independent of neuronal death after prolonged cardiac arrest in rats.
Anesthesia and analgesia 2009;109(3):914-23.
2009: Lesley M Foley; T Kevin Hitchens; Chien Ho; Keri L Janesko-Feldman; John A Melick; Hülya Bayir; Patrick M Kochanek
Magnetic resonance imaging assessment of macrophage accumulation in mouse brain after experimental traumatic brain injury.
Journal of neurotrauma 2009;26(9):1509-19.
2009: Ava M Puccio; Leslie A Hoffman; Hülya Bayir; Thomas G Zullo; Michael Fischer; Joseph M Darby; Sheila Alexander; C Edward Dixon; David O Okonkwo; Patrick M Kochanek
Effect of short periods of normobaric hyperoxia on local brain tissue oxygenation and cerebrospinal fluid oxidative stress markers in severe traumatic brain injury.
Journal of neurotrauma 2009;26(8):1241-9.
2009: Patrick M Kochanek; Robert C Tasker
Pediatric neurointensive care: 2008 update for the Rogers' Textbook of Pediatric Intensive Care.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2009;10(4):517-23.
2009: Valerian E Kagan; Hülya A Bayir; Natalia A Belikova; Olexandr Kapralov; Yulia Y Tyurina; Vladimir A Tyurin; Jianfei Jiang; Detcho Stoyanovsky; Peter Wipf; Patrick M Kochanek; Joel S Greenberger; Bruce Pitt; Anna A Shvedova; Grigory G Borisenko
Cytochrome c/cardiolipin relations in mitochondria: a kiss of death.
Free radical biology & medicine 2009;46(11):1439-53.
2009: Alia Marie Dennis; M Lee Haselkorn; Vincent A Vagni; Robert H Garman; Keri Janesko-Feldman; Hülya Bayir; Robert S B Clark; Larry W Jenkins; C Edward Dixon; Patrick M Kochanek
Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal death.
Journal of neurotrauma 2009;26(6):889-99.
2009: Patrick M Kochanek
Bakken Lecture: the brain, the heart, and therapeutic hypothermia.
Cleveland Clinic journal of medicine 2009;76 Suppl 2():S8-12.
2009: Manuella S Lahoud-Rahme; Jason Stezoski; Patrick M Kochanek; John Melick; Samuel A Tisherman; Tomas Drabek
Blood-brain barrier integrity in a rat model of emergency preservation and resuscitation.
Resuscitation 2009;80(4):484-8.
2009: Patrick M Kochanek; Tomas Drabek; Samuel A Tisherman
Therapeutic hypothermia: the Safar vision.
Journal of neurotrauma 2009;26(3):417-20.
2009: Hülya Bayir; P David Adelson; Stephen R Wisniewski; Paul Shore; YiChen Lai; Danielle Brown; Keri L Janesko-Feldman; Valerian E Kagan; Patrick M Kochanek
Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children.
Critical care medicine 2009;37(2):689-95.
2009: Michael A Tortorici; Ying Mu; Patrick M Kochanek; Wen Xie; Samuel M Poloyac
Moderate hypothermia prevents cardiac arrest-mediated suppression of drug metabolism and induction of interleukin-6 in rats.
Critical care medicine 2009;37(1):263-9.
2009: Mioara D Manole; Lesley M Foley; T Kevin Hitchens; Patrick M Kochanek; Robert W Hickey; Hülya Bayir; Henry Alexander; Chien Ho; Robert S B Clark
Magnetic resonance imaging assessment of regional cerebral blood flow after asphyxial cardiac arrest in immature rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(1):197-205.
2008: Muzamil Ahmad; Marie E Rose; Vincent Vagni; Raymond P Griffith; C Edward Dixon; Patrick M Kochanek; Robert W Hickey; Steven H Graham
Genetic disruption of cyclooxygenase-2 does not improve histological or behavioral outcome after traumatic brain injury in mice.
Journal of neuroscience research 2008;86(16):3605-12.
2008: Michael J Bell; Patrick M Kochanek
Traumatic brain injury in children: recent advances in management.
Indian journal of pediatrics 2008;75(11):1159-65.
2008: Fei Han; Tomas Drabek; Jason Stezoski; Keri Janesko-Feldman; S William Stezoski; Robert S B Clark; Hülya Bayir; Samuel A Tisherman; Patrick M Kochanek
Protein nitration and poly-ADP-ribosylation in brain after rapid exsanguination cardiac arrest in a rat model of emergency preservation and resuscitation.
Resuscitation 2008;79(2):301-10.
2008: Patrick M Kochanek; Michael J Bell; P David Adelson
Hypothermia therapy after traumatic brain injury in children.
The New England journal of medicine 2008;359(11):1179; author reply 1180.
2008: Ericka L Fink; Yichen Lai; Xiaopeng Zhang; Keri L Janesko-Feldman; P David Adelson; Csaba Szabó; Rachel Pardes Berger; Ajit A Sarnaik; Patrick M Kochanek; Robert S B Clark
Quantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(9):1523-9.
2008: Roya Tehranian; Marie E Rose; Vincent A Vagni; Alicia M Pickrell; Raymond P Griffith; Hao Liu; Robert S B Clark; C Edward Dixon; Patrick M Kochanek; Steven H Graham
Disruption of Bax protein prevents neuronal cell death but produces cognitive impairment in mice following traumatic brain injury.
Journal of neurotrauma 2008;25(7):755-67.
2008: Mioara D Manole; Robert W Hickey; Robert S B Clark; Patrick M Kochanek
Current and future therapies of pediatric cardiopulmonary arrest.
Indian journal of pediatrics 2008;75(6):609-14.
2008: Tomas Drabek; Fei Han; Robert H Garman; Jason Stezoski; Samuel A Tisherman; S William Stezoski; Ryan C Morhard; Patrick M Kochanek
Assessment of the delta opioid agonist DADLE in a rat model of lethal hemorrhage treated by emergency preservation and resuscitation.
Resuscitation 2008;77(2):220-8.
2008: Patrick M Kochanek; Rachel Pardes Berger; Hülya Bayir; Amy K Wagner; Larry W Jenkins; Robert S B Clark
Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making.
Current opinion in critical care 2008;14(2):135-41.
2008: Lesley M Foley; T Kevin Hitchens; John A Melick; Hülya Bayir; Chien Ho; Patrick M Kochanek
Effect of inducible nitric oxide synthase on cerebral blood flow after experimental traumatic brain injury in mice.
Journal of neurotrauma 2008;25(4):299-310.
2008: Tomas Drabek; Patrick M Kochanek
In quest of the optimal cooling device: isn't faster "too fast"?
Critical care medicine 2008;36(3):1018-20.
2008: Yichen Lai; Yaming Chen; simon simon watkins; Paula D Nathaniel; Fengli Guo; Patrick M Kochanek; Larry W Jenkins; Csaba Szabó; Robert S B Clark
Identification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury.
Journal of neurochemistry 2008;104(6):1700-11.
2008: Yichen Lai; Robert W Hickey; Yaming Chen; Hülya Bayir; Mara L Sullivan; Charleen T Chu; Patrick M Kochanek; C Edward Dixon; Larry W Jenkins; Steven H Graham; simon simon watkins; Robert S B Clark
Autophagy is increased after traumatic brain injury in mice and is partially inhibited by the antioxidant gamma-glutamylcysteinyl ethyl ester.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(3):540-50.
2008: Kathleen T Sachse; Edwin K Jackson; Stephen R Wisniewski; Delbert G Gillespie; Ava M Puccio; Robert S B Clark; C Edward Dixon; Patrick M Kochanek
Increases in cerebrospinal fluid caffeine concentration are associated with favorable outcome after severe traumatic brain injury in humans.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(2):395-401.
2008: Xianren Wu; Tomas Drabek; Samuel A Tisherman; Jeremy Henchir; S William Stezoski; Sherman Culver; Jason Stezoski; Edwin K Jackson; Robert H Garman; Patrick M Kochanek
Emergency preservation and resuscitation with profound hypothermia, oxygen, and glucose allows reliable neurological recovery after 3 h of cardiac arrest from rapid exsanguination in dogs.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(2):302-11.
2008: Vladimir A Tyurin; Yulia Y Tyurina; Patrick M Kochanek; Ronald Hamilton; Steven T DeKosky; Joel S Greenberger; Hülya Bayir; Valerian E Kagan
Oxidative lipidomics of programmed cell death.
Methods in enzymology 2008;442():375-93.
2007: Sandra D W Buttram; Stephen R Wisniewski; Edwin K Jackson; P David Adelson; Keri Feldman; Hülya Bayir; Rachel Pardes Berger; Robert S B Clark; Patrick M Kochanek
Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: effects of moderate hypothermia.
Journal of neurotrauma 2007;24(11):1707-17.
2007: Tomas Drabek; Jason Stezoski; Robert H Garman; Fei Han; Jeremy Henchir; Samuel A Tisherman; S William Stezoski; Patrick M Kochanek
Exsanguination cardiac arrest in rats treated by 60 min, but not 75 min, emergency preservation and delayed resuscitation is associated with intact outcome.
Resuscitation 2007;75(1):114-23.
2007: Michael A Tortorici; Patrick M Kochanek; Samuel M Poloyac
Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system.
Critical care medicine 2007;35(9):2196-204.
2007: Hülya Bayir; Vladimir A Tyurin; Yulia Y Tyurina; Rosa Viner; Vladimir B Ritov; Andrew A Amoscato; Qing Zhao; Xiaojing J Zhang; Keri L Janesko-Feldman; Henry Alexander; Liana V Basova; Robert S B Clark; Patrick M Kochanek; Valerian E Kagan
Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis.
Annals of neurology 2007;62(2):154-69.
2007: Tomas Drabek; Jesse A Fisk; C Edward Dixon; Robert H Garman; Jason Stezoski; Stephen R Wisnewski; Xianren Wu; Samuel A Tisherman; Patrick M Kochanek
Prolonged deep hypothermic circulatory arrest in rats can be achieved without cognitive deficits.
Life sciences 2007;81(7):543-52.
2007: Hülya Bayir; Valerian E Kagan; Robert S B Clark; Keri L Janesko-Feldman; Ruslan Rafikov; Zhentai Huang; Xiaojing Zhang; Vincent A Vagni; Timothy R Billiar; Patrick M Kochanek
Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury.
Journal of neurochemistry 2007;101(1):168-81.
2007: Tomas Drabek; Jason Stezoski; Robert H Garman; Xianren Wu; Samuel A Tisherman; S William Stezoski; Jesse A Fisk; Larry Jenkins; Patrick M Kochanek
Emergency preservation and delayed resuscitation allows normal recovery after exsanguination cardiac arrest in rats: a feasibility trial.
Critical care medicine 2007;35(2):532-7.
2007: Robert S B Clark; Paula D Nathaniel; Xiaopeng Zhang; C Edward Dixon; Sean Alber; simon simon watkins; John A Melick; Patrick M Kochanek; Steven H Graham
boc-Aspartyl(OMe)-fluoromethylketone attenuates mitochondrial release of cytochrome c and delays brain tissue loss after traumatic brain injury in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(2):316-26.
2007: Paul M Shore; Rachel P Berger; Sumeeta Varma; Keri L Janesko; Stephen R Wisniewski; Robert S B Clark; P David Adelson; Neal J Thomas; Yi-Chen Lai; Hülya Bayir; Patrick M Kochanek
Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury.
Journal of neurotrauma 2007;24(1):75-86.
2007: Wei-Min Gao; Mandeep S Chadha; Rachel Pardes Berger; Gilbert S Omenn; David L Allen; Michael Pisano; P David Adelson; Robert S B Clark; Larry W Jenkins; Patrick M Kochanek
A gel-based proteomic comparison of human cerebrospinal fluid between inflicted and non-inflicted pediatric traumatic brain injury.
Journal of neurotrauma 2007;24(1):43-53.
2006: Samuel M Poloyac; Yuqing Zhang; Robert R Bies; Patrick M Kochanek; Steven H Graham
Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(12):1551-61.
2006: Xiaopeng Zhang; Sean Alber; simon simon watkins; Patrick M Kochanek; Donald W Marion; Steven H Graham; Robert S B Clark
Proteolysis consistent with activation of caspase-7 after severe traumatic brain injury in humans.
Journal of neurotrauma 2006;23(11):1583-90.
2006: Rachel Pardes Berger; Patrick M Kochanek
Urinary S100B concentrations are increased after brain injury in children: A preliminary study.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2006;7(6):557-61.
2006: Roya Tehranian; Marie E Rose; Vincent A Vagni; R P Griffith; Shasha Wu; Sara Maits; Xiaopeng Zhang; Robert S B Clark; C Edward Dixon; Patrick M Kochanek; Ora Bernard; Steven H Graham
Transgenic mice that overexpress the anti-apoptotic Bcl-2 protein have improved histological outcome but unchanged behavioral outcome after traumatic brain injury.
Brain research 2006;1101(1):126-35.
2006: Paul M Shore; Linda L Hand; Lonnie Roy; Premal Trivedi; Patrick M Kochanek; P David Adelson
Reliability and validity of the Pediatric Intensity Level of Therapy (PILOT) scale: a measure of the use of intracranial pressure-directed therapies.
Critical care medicine 2006;34(7):1981-7.
2006: Xiaopeng Zhang; Yaming Chen; Milos D Ikonomovic; Paula D Nathaniel; Patrick M Kochanek; Donald W Marion; Steven T DeKosky; Larry W Jenkins; Robert S B Clark
Increased phosphorylation of protein kinase B and related substrates after traumatic brain injury in humans and rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(7):915-26.
2006: Ala Nozari; Peter Safar; S William Stezoski; Xianren Wu; Scott Kostelnik; Ann Radovsky; Samuel A Tisherman; Patrick M Kochanek
Critical time window for intra-arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation.
Circulation 2006;113(23):2690-6.
2006: Yulia Y Tyurina; Alexandr A Kapralov; Jianfei Jiang; Grigory G Borisenko; Alla I Potapovich; Andrey Sorokin; Patrick M Kochanek; Steven H Graham; Nina F Schor; Valerian E Kagan
Oxidation and cytotoxicity of 6-OHDA are mediated by reactive intermediates of COX-2 overexpressed in PC12 cells.
Brain research 2006;1093(1):71-82.
2006: Hülya Bayir; Bengt Fadeel; M J Palladino; Erika Witasp; Igor V Kurnikov; Yulia Y Tyurina; Vladimir A Tyurin; Andrew A Amoscato; Jianfei Jiang; Patrick M Kochanek; Steven T DeKosky; Joel S Greenberger; Anna A Shvedova; Valerian E Kagan
Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria.
Biochimica et biophysica acta 2006;1757(5-6):648-59.
2006: Xianren Wu; Tomas Drabek; Patrick M Kochanek; Jeremy Henchir; S William Stezoski; Jason Stezoski; Kristin Cochran; Robert H Garman; Samuel A Tisherman
Induction of profound hypothermia for emergency preservation and resuscitation allows intact survival after cardiac arrest resulting from prolonged lethal hemorrhage and trauma in dogs.
Circulation 2006;113(16):1974-82.
2006: Patrick M Kochanek; Vincent A Vagni; Keri L Janesko; Christopher B Washington; Patricia K Crumrine; Robert H Garman; Larry W Jenkins; Robert S B Clark; Gregg E Homanics; C Edward Dixon; Jurgen Schnermann; Edwin K Jackson
Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(4):565-75.
2006: Kimberly D Statler; Henry Alexander; Vincent A Vagni; Richard Holubkov; C Edward Dixon; Robert S B Clark; Larry Jenkins; Patrick M Kochanek
Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injury.
Brain research 2006;1076(1):216-24.
2006: Michael A Tortorici; Patrick M Kochanek; Robert R Bies; Samuel M Poloyac
Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model.
Critical care medicine 2006;34(3):785-91.
2006: Rachel Pardes Berger; Tina Dulani; P David Adelson; John M Leventhal; Rudolph Richichi; Patrick M Kochanek
Identification of inflicted traumatic brain injury in well-appearing infants using serum and cerebrospinal markers: a possible screening tool.
Pediatrics 2006;117(2):325-32.
2006: Wei-Min Gao; Mandeep S Chadha; Anthony E Kline; Robert S B Clark; Patrick M Kochanek; C Edward Dixon; Larry W Jenkins
Immunohistochemical analysis of histone H3 acetylation and methylation--evidence for altered epigenetic signaling following traumatic brain injury in immature rats.
Brain research 2006;1070(1):31-4.
2006: Hülya Bayir; Patrick M Kochanek; Valerian E Kagan
Oxidative stress in immature brain after traumatic brain injury.
Developmental neuroscience 2006;28(4-5):420-31.
2006: J'mir L Cousar; Yichen Lai; Christina D Marco; Hülya Bayir; P David Adelson; Keri L Janesko-Feldman; Patrick M Kochanek; Robert S B Clark
Heme oxygenase 1 in cerebrospinal fluid from infants and children after severe traumatic brain injury.
Developmental neuroscience 2006;28(4-5):342-7.
2006: Yichen Lai; Christopher Stange; Stephen R Wisniewski; P David Adelson; Keri L Janesko-Feldman; Danielle S Brown; Patrick M Kochanek; Robert S B Clark
Mitochondrial heat shock protein 60 is increased in cerebrospinal fluid following pediatric traumatic brain injury.
Developmental neuroscience 2006;28(4-5):336-41.
2006: Rachel Pardes Berger; P David Adelson; Rudolph Richichi; Patrick M Kochanek
Serum biomarkers after traumatic and hypoxemic brain injuries: insight into the biochemical response of the pediatric brain to inflicted brain injury.
Developmental neuroscience 2006;28(4-5):327-35.
2006: Patrick M Kochanek
Pediatric traumatic brain injury: quo vadis?
Developmental neuroscience 2006;28(4-5):244-55.
2006: Kimberly D Statler; Henry Alexander; Vincent A Vagni; C Edward Dixon; Robert S B Clark; Larry Jenkins; Patrick M Kochanek
Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats.
Journal of neurotrauma 2006;23(1):97-108.
2006: Patrick M Kochanek; Robert S B Clark; Kimberly D Statler; Larry W Jenkins
Physiological assessment and control in studies evaluating central nervous system injury: should size matter?
Anesthesia and analgesia 2006;102(1):72-4.
2005: Patrick M Kochanek; Kristy S Hendrich; Edwin K Jackson; Stephen R Wisniewski; John A Melick; Paul M Shore; Keri L Janesko; Lefteris C Zacharia; Chien Ho
Characterization of the effects of adenosine receptor agonists on cerebral blood flow in uninjured and traumatically injured rat brain using continuous arterial spin-labeled magnetic resonance imaging.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(12):1596-612.
2005: Patrick M Kochanek
Pediatric traumatic brain injury: beyond the guidelines.
Current treatment options in neurology 2005;7(6):441-50.
2005: Lesley M Foley; T Kevin Hitchens; Patrick M Kochanek; John A Melick; Edwin K Jackson; Chien Ho
Murine orthostatic response during prolonged vertical studies: effect on cerebral blood flow measured by arterial spin-labeled MRI.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;54(4):798-806.
2005: Xianren Wu; Patrick M Kochanek; Kristin Cochran; Ala Nozari; Jeremy Henchir; S William Stezoski; Robert Wagner; Stephen R Wisniewski; Samuel A Tisherman
Mild hypothermia improves survival after prolonged, traumatic hemorrhagic shock in pigs.
The Journal of trauma 2005;59(2):291-9; discussion 299-301.
2005: Rachel Pardes Berger; P David Adelson; Mary Clyde Pierce; Tina Dulani; Laura D Cassidy; Patrick M Kochanek
Serum neuron-specific enolase, S100B, and myelin basic protein concentrations after inflicted and noninflicted traumatic brain injury in children.
Journal of neurosurgery 2005;103(1 Suppl):61-8.
2005: Margaret A Satchell; Yichen Lai; Patrick M Kochanek; Stephen R Wisniewski; Ericka L Fink; Neal A Siedberg; Rachel Pardes Berger; Steven T DeKosky; P David Adelson; Robert S B Clark
Cytochrome c, a biomarker of apoptosis, is increased in cerebrospinal fluid from infants with inflicted brain injury from child abuse.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(7):919-27.
2005: Hülya Bayir; Valerian E Kagan; Grigory G Borisenko; Yulia Y Tyurina; Keri L Janesko; Vincent A Vagni; Timothy R Billiar; Deborah L Williams; Patrick M Kochanek
Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(6):673-84.
2005: Ericka L Fink; Christina D Marco; Holly A Donovan; Henry Alexander; C Edward Dixon; Larry W Jenkins; Christopher J Stange; Patrick M Kochanek; Robert S B Clark
Brief induced hypothermia improves outcome after asphyxial cardiopulmonary arrest in juvenile rats.
Developmental neuroscience 2005;27(2-4):191-9.
2005: Xiaopeng Zhang; Yaming Chen; Larry W Jenkins; Patrick M Kochanek; Robert S B Clark
Bench-to-bedside review: Apoptosis/programmed cell death triggered by traumatic brain injury.
Critical care (London, England) 2005;9(1):66-75.
2004: Ala Nozari; Peter Safar; Xianren Wu; William S Stezoski; Jeremy Henchir; Patrick M Kochanek; Miroslav Klain; Ann Radovsky; Samuel A Tisherman
Suspended animation can allow survival without brain damage after traumatic exsanguination cardiac arrest of 60 minutes in dogs.
The Journal of trauma 2004;57(6):1266-75.
2004: Ala Nozari; Peter Safar; S William Stezoski; Xianren Wu; Jeremy Henchir; Ann Radovsky; Kristin Hanson; Edwin Klein; Patrick M Kochanek; Samuel A Tisherman
Mild hypothermia during prolonged cardiopulmonary cerebral resuscitation increases conscious survival in dogs.
Critical care medicine 2004;32(10):2110-6.
2004: Lina Du; Hülya Bayir; Yichen Lai; Xiaopeng Zhang; Patrick M Kochanek; simon simon watkins; Steven H Graham; Robert S B Clark
Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway.
The Journal of biological chemistry 2004;279(37):38563-70.
2004: Rachel Pardes Berger; Melvyn P Heyes; Stephen R Wisniewski; P David Adelson; Neal Thomas; Patrick M Kochanek
Assessment of the macrophage marker quinolinic acid in cerebrospinal fluid after pediatric traumatic brain injury: insight into the timing and severity of injury in child abuse.
Journal of neurotrauma 2004;21(9):1123-30.
2004: Paul M Shore; Neal J Thomas; Robert S B Clark; P David Adelson; Stephen R Wisniewski; Keri L Janesko; Hülya Bayir; Edwin K Jackson; Patrick M Kochanek
Continuous versus intermittent cerebrospinal fluid drainage after severe traumatic brain injury in children: effect on biochemical markers.
Journal of neurotrauma 2004;21(9):1113-22.
2004: Steven T DeKosky; Eric Abrahamson; Kevin M Taffe; C Edward Dixon; Patrick M Kochanek; Milos D Ikonomovic
Effects of post-injury hypothermia and nerve growth factor infusion on antioxidant enzyme activity in the rat: implications for clinical therapies.
Journal of neurochemistry 2004;90(4):998-1004.
2004: Rachel Pardes Berger; Patrick M Kochanek; Mary Clyde Pierce
Biochemical markers of brain injury: could they be used as diagnostic adjuncts in cases of inflicted traumatic brain injury?
Child abuse & neglect 2004;28(7):739-54.
2004: Steven T DeKosky; Kevin M Taffe; Eric Abrahamson; C Edward Dixon; Patrick M Kochanek; Milos D Ikonomovic
Time course analysis of hippocampal nerve growth factor and antioxidant enzyme activity following lateral controlled cortical impact brain injury in the rat.
Journal of neurotrauma 2004;21(5):491-500.
2004: Yichen Lai; Patrick M Kochanek; P David Adelson; Keri L Janesko; Randall A Ruppel; Robert S B Clark
Induction of the stress response after inflicted and non-inflicted traumatic brain injury in infants and children.
Journal of neurotrauma 2004;21(3):229-37.
2004: Paul M Shore; Edwin K Jackson; Stephen R Wisniewski; Robert S B Clark; P David Adelson; Patrick M Kochanek
Vascular endothelial growth factor is increased in cerebrospinal fluid after traumatic brain injury in infants and children.
Neurosurgery 2004;54(3):605-11; discussion 611-2.
2004: Ake Grenvik; Patrick M Kochanek
The incredible career of Peter J. Safar, MD: the Michelangelo of acute medicine.
Critical care medicine 2004;32(2 Suppl):S3-7.
2004: Amy K Wagner; Hülya Bayir; Dianxu Ren; Ava M Puccio; Ross D Zafonte; Patrick M Kochanek
Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia.
Journal of neurotrauma 2004;21(2):125-36.
2004: Hülya Bayir; Donald W Marion; Ava M Puccio; Stephen R Wisniewski; Keri L Janesko; Robert S B Clark; Patrick M Kochanek
Marked gender effect on lipid peroxidation after severe traumatic brain injury in adult patients.
Journal of neurotrauma 2004;21(1):1-8.
2003: Kimberly D Statler; Keri L Janesko; John A Melick; Robert S B Clark; Larry W Jenkins; Patrick M Kochanek
Hyperglycolysis is exacerbated after traumatic brain injury with fentanyl vs. isoflurane anesthesia in rats.
Brain research 2003;994(1):37-43.
2003: Patrick M Kochanek; Ake Grenvik
A tribute to Peter J. Safar, MD.
Critical care medicine 2003;31(11):2571-3.
2003: C Edward Dixon; Xiecheng Ma; Anthony E Kline; Hong Qu Yan; Howard Ferimer; Patrick M Kochanek; Stephen R Wisniewski; Larry W Jenkins; Donald W Marion
Acute etomidate treatment reduces cognitive deficits and histopathology in rats with traumatic brain injury.
Critical care medicine 2003;31(8):2222-7.
2003: Sumeeta Varma; Keri L Janesko; Stephen R Wisniewski; Hülya Bayir; P David Adelson; Neal J Thomas; Patrick M Kochanek
F2-isoprostane and neuron-specific enolase in cerebrospinal fluid after severe traumatic brain injury in infants and children.
Journal of neurotrauma 2003;20(8):781-6.
2003: Hülya Bayir; Patrick M Kochanek; Robert S B Clark
Traumatic brain injury in infants and children: mechanisms of secondary damage and treatment in the intensive care unit.
Critical care clinics 2003;19(3):529-49.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael P Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 19. The role of anti-seizure prophylaxis following severe pediatric traumatic brain injury.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S72-5.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 18. Nutritional support.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S68-71.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig W Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 17. Critical pathway for the treatment of established intracranial hypertension in pediatric traumatic brain injury.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S65-7.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 16. The use of corticosteroids in the treatment of severe pediatric traumatic brain injury.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S60-4.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 15. Surgical treatment of pediatric intracranial hypertension.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S56-9.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 14. The role of temperature control following severe pediatric traumatic brain injury.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S53-5.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 13. The use of barbiturates in the control of intracranial hypertension in severe pediatric traumatic brain injury.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S49-52.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 12. Use of hyperventilation in the acute management of severe pediatric traumatic brain injury.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S45-8.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 11. Use of hyperosmolar therapy in the management of severe pediatric traumatic brain injury.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S40-4.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 10. The role of cerebrospinal fluid drainage in the treatment of severe pediatric traumatic brain injury.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S38-9.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 9. Use of sedation and neuromuscular blockade in the treatment of severe pediatric traumatic brain injury.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S34-7.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 8. Cerebral perfusion pressure.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S31-3.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 7. Intracranial pressure monitoring technology.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S28-30.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 6. Threshold for treatment of intracranial hypertension.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S25-7.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 5. Indications for intracranial pressure monitoring in pediatric patients with severe traumatic brain injury.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S19-24.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 4. Resuscitation of blood pressure and oxygenation and prehospital brain-specific therapies for the severe pediatric traumatic brain injury patient.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S12-8.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 2: Trauma systems, pediatric trauma centers, and the neurosurgeon.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S5-8.
2003: P David Adelson; Susan L Bratton; Nancy A Carney; Randall M Chesnut; Hugo E M du Coudray; Brahm Goldstein; Patrick M Kochanek; Helen C Miller; Michael D Partington; Nathan R Selden; Craig R Warden; David W Wright
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 1: Introduction.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3 Suppl):S2-4.
2003: Xiaopeng Zhang; Steven H Graham; Patrick M Kochanek; Donald W Marion; Paula D Nathaniel; simon simon watkins; Robert S B Clark
Caspase-8 expression and proteolysis in human brain after severe head injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(10):1367-9.
2003: Lina Du; Xiaopeng Zhang; Yong Y Han; Nancy A Burke; Patrick M Kochanek; simon simon watkins; Steven H Graham; Joseph A Carcillo; Csaba Szabó; Robert S B Clark
Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress.
The Journal of biological chemistry 2003;278(20):18426-33.
2003: Wilhelm Behringer; Peter Safar; Xianren Wu; Rainer Kentner; Ann Radovsky; Patrick M Kochanek; C Edward Dixon; Samuel A Tisherman
Survival without brain damage after clinical death of 60-120 mins in dogs using suspended animation by profound hypothermia.
Critical care medicine 2003;31(5):1523-31.
2003: Margaret A Satchell; Xiaopeng Zhang; Patrick M Kochanek; C Edward Dixon; Larry W Jenkins; John A Melick; Csaba Szabó; Robert S B Clark
A dual role for poly-ADP-ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14-3-3gamma.
Journal of neurochemistry 2003;85(3):697-708.
2003: Kimberly D Statler; Henry L Alexander; Vincent A Vagni; Edwin M Nemoto; Stevan P Tofovic; C Edward Dixon; Larry W Jenkins; Donald W Marion; Patrick M Kochanek
Moderate hypothermia may be detrimental after traumatic brain injury in fentanyl-anesthetized rats.
Critical care medicine 2003;31(4):1134-9.
2003: Robert W Hickey; Patrick M Kochanek; Howard Ferimer; Henry L Alexander; Robert H Garman; Steven H Graham
Induced hyperthermia exacerbates neurologic neuronal histologic damage after asphyxial cardiac arrest in rats.
Critical care medicine 2003;31(2):531-5.
2003: Neal A Seidberg; Robert S B Clark; Xiaopeng Zhang; Yichen Lai; Minzhi Chen; Steven H Graham; Patrick M Kochanek; simon simon watkins; Donald W Marion
Alterations in inducible 72-kDa heat shock protein and the chaperone cofactor BAG-1 in human brain after head injury.
Journal of neurochemistry 2003;84(3):514-21.
2003: Xianren Wu; Jason Stezoski; Peter Safar; Anthony Bauer; Andreas Tuerler; Nicholas Schwarz; Rainer Kentner; Wilhelm Behringer; Patrick M Kochanek; Samuel A Tisherman
Mild hypothermia during hemorrhagic shock in rats improves survival without significant effects on inflammatory responses.
Critical care medicine 2003;31(1):195-202.
2003: Hülya Bayir; Robert S B Clark; Patrick M Kochanek
Promising strategies to minimize secondary brain injury after head trauma.
Critical care medicine 2003;31(1 Suppl):S112-7.
2003: Hülya Bayir; Patrick M Kochanek; Shang-Xi Liu; Antonio Arroyo; Anatoly Osipov; Jianfei Jiang; Stephen R Wisniewski; P David Adelson; Steven H Graham; Valerian E Kagan
Increased S-nitrosothiols and S-nitrosoalbumin in cerebrospinal fluid after severe traumatic brain injury in infants and children: indirect association with intracranial pressure.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(1):51-61.
2002: John R Ciallella; Milos D Ikonomovic; William R Paljug; Yetta I Wilbur; C Edward Dixon; Patrick M Kochanek; Donald W Marion; Steven T DeKosky
Changes in expression of amyloid precursor protein and interleukin-1beta after experimental traumatic brain injury in rats.
Journal of neurotrauma 2002;19(12):1555-67.
2002: Donald W Marion; Ava M Puccio; Stephen R Wisniewski; Patrick M Kochanek; C Edward Dixon; Leann Bullian; Patricia Carlier
Effect of hyperventilation on extracellular concentrations of glutamate, lactate, pyruvate, and local cerebral blood flow in patients with severe traumatic brain injury.
Critical care medicine 2002;30(12):2619-25.
2002: Rachel Pardes Berger; Mary Clyde Pierce; Stephen R Wisniewski; P David Adelson; Patrick M Kochanek
Serum S100B concentrations are increased after closed head injury in children: a preliminary study.
Journal of neurotrauma 2002;19(11):1405-9.
2002: Manu R Varma; C Edward Dixon; Edwin K Jackson; Grant W Peters; John A Melick; Raymond P Griffith; Vincent A Vagni; Robert S B Clark; Larry W Jenkins; Patrick M Kochanek
Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology.
Brain research 2002;951(2):191-201.
2002: Xianren Wu; Jason Stezoski; Peter Safar; Wilhelm Behringer; Rainer Kentner; Patrick M Kochanek; Samuel A Tisherman
Systemic hypothermia, but not regional gut hypothermia, improves survival from prolonged hemorrhagic shock in rats.
The Journal of trauma 2002;53(4):654-62.
2002: Patrick M Kochanek; Kristy S Hendrich; C Edward Dixon; Joanne K Schiding; Donald S Williams; Chien Ho
Cerebral blood flow at one year after controlled cortical impact in rats: assessment by magnetic resonance imaging.
Journal of neurotrauma 2002;19(9):1029-37.
2002: Marie E Rose; Michele B Huerbin; John A Melick; Donald W Marion; Alan M Palmer; Joanne K Schiding; Patrick M Kochanek; Steven H Graham
Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury.
Brain research 2002;943(1):15-22.
2002: Patrick M Kochanek; Joseph E Parrillo
Publication of Cochrane Reviews in Critical Care Medicine and Pediatric Critical Care Medicine: guiding practice or duplicating the literature?
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2002;3(3):221-2.
2002: Xiaopeng Zhang; Jun Chen; Steven H Graham; Lina Du; Patrick M Kochanek; Romesh A Draviam; Fengli Guo; Paula D Nathaniel; Csaba Szabó; simon simon watkins; Robert S B Clark
Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite.
Journal of neurochemistry 2002;82(1):181-91.
2002: Larry W Jenkins; G W Peters; C Edward Dixon; Xiaopeng Zhang; R S B Clark; J C Skinner; Donald W Marion; P David Adelson; Patrick M Kochanek
Conventional and functional proteomics using large format two-dimensional gel electrophoresis 24 hours after controlled cortical impact in postnatal day 17 rats.
Journal of neurotrauma 2002;19(6):715-40.
2002: Anthony E Kline; Bryan D Bolinger; Patrick M Kochanek; Timothy M Carlos; Hong Qu Yan; Larry W Jenkins; Donald W Marion; C Edward Dixon
Acute systemic administration of interleukin-10 suppresses the beneficial effects of moderate hypothermia following traumatic brain injury in rats.
Brain research 2002;937(1-2):22-31.
2002: Marie E Rose; Michele B Huerbin; John A Melick; Donald W Marion; Alan M Palmer; Joanne K Schiding; Patrick M Kochanek; Steven H Graham
Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury.
Brain research 2002;935(1-2):40-6.
2002: Hülya Bayir; Valerian E Kagan; Yulia Y Tyurina; Vladimir A Tyurin; Randall A Ruppel; P David Adelson; Steven H Graham; Keri L Janesko; Robert S B Clark; Patrick M Kochanek
Assessment of antioxidant reserves and oxidative stress in cerebrospinal fluid after severe traumatic brain injury in infants and children.
Pediatric research 2002;51(5):571-8.
2002: Randall A Ruppel; Robert S B Clark; Hülya Bayir; Margaret A Satchell; Patrick M Kochanek
Critical mechanisms of secondary damage after inflicted head injury in infants and children.
Neurosurgery clinics of North America 2002;13(2):169-82, v.
2002: Rachel Pardes Berger; Mary Clyde Pierce; Stephen R Wisniewski; P David Adelson; Robert S B Clark; Randall A Ruppel; Patrick M Kochanek
Neuron-specific enolase and S100B in cerebrospinal fluid after severe traumatic brain injury in infants and children.
Pediatrics 2002;109(2):E31.
2002: Yong Y Han; Joseph A Carcillo; Randall A Ruppel; P David Adelson; Stephen R Wisniewski; Michael J Bell; Keri L Janesko; Donald W Marion; Patrick M Kochanek
Cerebrospinal fluid procalcitonin and severe traumatic brain injury in children.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2002;3(1):39-44.
2002: Wilhelm Behringer; Peter Safar; Rainer Kentner; Xianren Wu; Valerian E Kagan; Ann Radovsky; Robert S B Clark; Patrick M Kochanek; Murugan Subramanian; Vladimir A Tyurin; Yulia Y Tyurina; Samuel A Tisherman
Antioxidant Tempol enhances hypothermic cerebral preservation during prolonged cardiac arrest in dogs.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(1):105-17.
2001: Courtney L Robertson; Michael J Bell; Patrick M Kochanek; P David Adelson; Randall A Ruppel; Joseph A Carcillo; Stephen R Wisniewski; Zaichuan Mi; Keri L Janesko; Robert S B Clark; Donald W Marion; Steven H Graham; Edwin K Jackson
Increased adenosine in cerebrospinal fluid after severe traumatic brain injury in infants and children: association with severity of injury and excitotoxicity.
Critical care medicine 2001;29(12):2287-93.
2001: Xianren Wu; Stephan Prueckner; Florence M Rollwagen; Rainer Kentner; Jason Stezoski; Patrick M Kochanek; Wilhelm Behringer; William Pasculle; Peter Safar; Samuel A Tisherman
Gut damage during hemorrhagic shock: effects on survival of oral or enteral interleukin-6.
Shock (Augusta, Ga.) 2001;16(6):449-53.
2001: Kimberly D Statler; Larry W Jenkins; C Edward Dixon; Robert S B Clark; Donald W Marion; Patrick M Kochanek
The simple model versus the super model: translating experimental traumatic brain injury research to the bedside.
Journal of neurotrauma 2001;18(11):1195-206.
2001: P David Adelson; Larry W Jenkins; R L Hamilton; P Robichaud; M P Tran; Patrick M Kochanek
Histopathologic response of the immature rat to diffuse traumatic brain injury.
Journal of neurotrauma 2001;18(10):967-76.
2001: Courtney L Robertson; N Minamino; Randall A Ruppel; K Kangawa; Stephen R Wisniewski; T Tsuji; Keri L Janesko; H Ohta; P David Adelson; Donald W Marion; Patrick M Kochanek
Increased adrenomedullin in cerebrospinal fluid after traumatic brain injury in infants and children.
Journal of neurotrauma 2001;18(9):861-8.
2001: Xianren Wu; Rainer Kentner; Jason Stezoski; Patrick M Kochanek; Edwin K Jackson; Timothy M Carlos; Joseph A Carcillo; Wilhelm Behringer; Peter Safar; Samuel A Tisherman
Intraperitoneal, but not enteric, adenosine administration improves survival after volume-controlled hemorrhagic shock in rats.
Critical care medicine 2001;29(9):1767-73.
2001: Minzhi Chen; Patrick M Kochanek; simon simon watkins; KL Jin; Romesh A Draviam; Paula D Nathaniel; R Pinto; Donald W Marion; Steven H Graham
Detection of single- and double-strand DNA breaks after traumatic brain injury in rats: comparison of in situ labeling techniques using DNA polymerase I, the Klenow fragment of DNA polymerase I, and terminal deoxynucleotidyl transferase.
Journal of neurotrauma 2001;18(7):675-89.
2001: Kristy S Hendrich; Patrick M Kochanek; John A Melick; Joanne K Schiding; Kimberly D Statler; Donald S Williams; Donald W Marion; Chien Ho
Cerebral perfusion during anesthesia with fentanyl, isoflurane, or pentobarbital in normal rats studied by arterial spin-labeled MRI.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2001;46(1):202-6.
2001: Patrick M Kochanek; Robert S B Clark; Randall A Ruppel; C Edward Dixon
Cerebral resuscitation after traumatic brain injury and cardiopulmonary arrest in infants and children in the new millennium.
Pediatric clinics of North America 2001;48(3):661-81.
2001: Patrick M Kochanek; Kristy S Hendrich; Courtney L Robertson; Donald S Williams; John A Melick; Chien Ho; Donald W Marion; Edwin K Jackson
Assessment of the effect of 2-chloroadenosine in normal rat brain using spin-labeled MRI measurement of perfusion.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2001;45(5):924-9.
2001: Michael J Bell; Claudia S Robertson; Patrick M Kochanek; J Clay Goodman; Shankar Gopinath; Joseph A Carcillo; Robert S B Clark; Donald W Marion; Zaichuan Mi; Edwin K Jackson
Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury.
Critical care medicine 2001;29(2):399-404.
2001: Patrick M Kochanek; Keri L Janesko; Larry W Jenkins; Hong Qu Yan; Melina R Kibbe; P Robichaud; A C Wooditch; Robert S B Clark; C Edward Dixon; Donald W Marion; Timothy R Billiar
Adenovirus-mediated transfer and expression of beta-gal in injured hippocampus after traumatic brain injury in mice.
Journal of neurotrauma 2001;18(1):73-82.
2001: Randall A Ruppel; Patrick M Kochanek; P David Adelson; Marie E Rose; Stephen R Wisniewski; Michael J Bell; Robert S B Clark; Donald W Marion; Steven H Graham
Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuse.
The Journal of pediatrics 2001;138(1):18-25.
2000: Kimberly D Statler; Patrick M Kochanek; C Edward Dixon; Henry L Alexander; Warner David; Robert S B Clark; Stephen R Wisniewski; Steven H Graham; Larry W Jenkins; Donald W Marion; Peter Safar
Isoflurane improves long-term neurologic outcome versus fentanyl after traumatic brain injury in rats.
Journal of neurotrauma 2000;17(12):1179-89.
2000: Michael J Whalen; Timothy M Carlos; Stephen R Wisniewski; Robert S B Clark; J A Mellick; Donald W Marion; Patrick M Kochanek
Effect of neutropenia and granulocyte colony stimulating factor-induced neutrophilia on blood-brain barrier permeability and brain edema after traumatic brain injury in rats.
Critical care medicine 2000;28(11):3710-7.
2000: Vladimir A Tyurin; Yulia Y Tyurina; Grigory G Borisenko; Tatyana V Sokolova; Vladimir B Ritov; Peter J Quinn; M Rose; Patrick M Kochanek; Steven H Graham; Valerian E Kagan
Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates.
Journal of neurochemistry 2000;75(5):2178-89.
2000: Robert W Hickey; Howard Ferimer; Henry L Alexander; R H Garman; Clifton Callaway; S Hicks; Peter Safar; Steven H Graham; Patrick M Kochanek
Delayed, spontaneous hypothermia reduces neuronal damage after asphyxial cardiac arrest in rats.
Critical care medicine 2000;28(10):3511-6.
2000: P Safar; Patrick M Kochanek; N Bircher
Cardiopulmonary resuscitation by chest compression alone.
The New England journal of medicine 2000;343(11):816; author reply 816-7.
2000: Courtney L Robertson; Robert S B Clark; C Edward Dixon; Henry L Alexander; Steven H Graham; Stephen R Wisniewski; Donald W Marion; Peter Safar; Patrick M Kochanek
No long-term benefit from hypothermia after severe traumatic brain injury with secondary insult in rats.
Critical care medicine 2000;28(9):3218-23.
2000: Robert S B Clark; Patrick M Kochanek; P David Adelson; Michael J Bell; Joseph A Carcillo; M Chen; Stephen R Wisniewski; Keri L Janesko; Michael J Whalen; Steven H Graham
Increases in bcl-2 protein in cerebrospinal fluid and evidence for programmed cell death in infants and children after severe traumatic brain injury.
The Journal of pediatrics 2000;137(2):197-204.
2000: Michael J Whalen; Lesley A Doughty; Timothy M Carlos; Stephen R Wisniewski; Patrick M Kochanek; Joseph A Carcillo
Intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 are increased in the plasma of children with sepsis-induced multiple organ failure.
Critical care medicine 2000;28(7):2600-7.
2000: Robert W Hickey; Patrick M Kochanek; Howard Ferimer; Steven H Graham; Peter Safar
Hypothermia and hyperthermia in children after resuscitation from cardiac arrest.
Pediatrics 2000;106(1 Pt 1):118-22.
2000: Robert W Hickey; RL Zhu; Henry L Alexander; KL Jin; R Anne Stetler; Jun Chen; Patrick M Kochanek; Steven H Graham
10 kD mitochondrial matrix heat shock protein mRNA is induced following global brain ischemia in the rat.
Brain research. Molecular brain research 2000;79(1-2):169-73.
2000: Michael J Whalen; Timothy M Carlos; Patrick M Kochanek; Stephen R Wisniewski; Michael J Bell; Robert S B Clark; Steven T DeKosky; Donald W Marion; P David Adelson
Interleukin-8 is increased in cerebrospinal fluid of children with severe head injury.
Critical care medicine 2000;28(4):929-34.
2000: P David Adelson; C E Dixon; Patrick M Kochanek
Long-term dysfunction following diffuse traumatic brain injury in the immature rat.
Journal of neurotrauma 2000;17(4):273-82.
2000: RJ Woods; Stephan Prueckner; Peter Safar; A Takasu; Samuel A Tisherman; Edwin K Jackson; Ann Radovsky; Patrick M Kochanek; Wilhelm Behringer; S William Stezoski; R Hans
Adenosine by aortic flush fails to augment the brain preservation effect of mild hypothermia during exsanguination cardiac arrest in dogs - an exploratory study.
Resuscitation 2000;44(1):47-59.
2000: Michael J Whalen; Timothy M Carlos; C Edward Dixon; P Robichaud; Robert S B Clark; Donald W Marion; Patrick M Kochanek
Reduced brain edema after traumatic brain injury in mice deficient in P-selectin and intercellular adhesion molecule-1.
Journal of leukocyte biology 2000;67(2):160-8.
2000: Robert S B Clark; Patrick M Kochanek; simon simon watkins; Minzhi Chen; C Edward Dixon; N A Seidberg; John A Melick; JE Loeffert; Paula D Nathaniel; KL Jin; Steven H Graham
Caspase-3 mediated neuronal death after traumatic brain injury in rats.
Journal of neurochemistry 2000;74(2):740-53.
2000: Michael J Whalen; Robert S B Clark; C Edward Dixon; P Robichaud; Donald W Marion; Vincent A Vagni; S Graham; Laszlo Virag; G Hasko; R Stachlewitz; Csaba Szabó; Patrick M Kochanek
Traumatic brain injury in mice deficient in poly-ADP(ribose) polymerase: a preliminary report.
Acta neurochirurgica. Supplement 2000;76():61-4.
2000: Courtney L Robertson; N Minamino; Randall A Ruppel; K Kangawa; P David Adelson; T Tsuji; Stephen R Wisniewski; H Ohta; Keri L Janesko; Patrick M Kochanek
Increased adrenomedullin in cerebrospinal fluid after traumatic brain injury in children: a preliminary report.
Acta neurochirurgica. Supplement 2000;76():419-21.
2000: Courtney L Robertson; Kristy S Hendrich; Patrick M Kochanek; Edwin K Jackson; John A Melick; Steven H Graham; Donald W Marion; Donald S Williams; Chien Ho
Assessment of 2-chloroadenosine treatment after experimental traumatic brain injury in the rat using arterial spin-labeled MRI: a preliminary report.
Acta neurochirurgica. Supplement 2000;76():187-9.
1999: Kristy S Hendrich; Patrick M Kochanek; Donald S Williams; Joanne K Schiding; Donald W Marion; Chien Ho
Early perfusion after controlled cortical impact in rats: quantification by arterial spin-labeled MRI and the influence of spin-lattice relaxation time heterogeneity.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1999;42(4):673-81.
1999: EH Sinz; Patrick M Kochanek; C Edward Dixon; Robert S B Clark; Joseph A Carcillo; Joanne K Schiding; Minzhi Chen; Stephen R Wisniewski; Timothy M Carlos; D Williams; Steven T DeKosky; simon simon watkins; Donald W Marion; Timothy R Billiar
Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice.
The Journal of clinical investigation 1999;104(5):647-56.
1999: Michael J Whalen; Robert S B Clark; C Edward Dixon; P Robichaud; Donald W Marion; Vincent A Vagni; Steven H Graham; Laszlo Virag; G Hasko; R Stachlewitz; Csaba Szabó; Patrick M Kochanek
Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(8):835-42.
1999: Michael J Whalen; Timothy M Carlos; Patrick M Kochanek; Robert S B Clark; S Heineman; Joanne K Schiding; Darcy Franicola; F Memarzadeh; W Lo; Donald W Marion; Steven T DeKosky
Neutrophils do not mediate blood-brain barrier permeability early after controlled cortical impact in rats.
Journal of neurotrauma 1999;16(7):583-94.
1999: Michael J Whalen; Timothy M Carlos; Robert S B Clark; Patrick M Kochanek
An acute inflammatory response to the use of granulocyte colony-stimulating factor to prevent infections in patients with brain injury: what about the brain?
Critical care medicine 1999;27(5):1014-8.
1999: Robert S B Clark; Patrick M Kochanek; Minzhi Chen; simon simon watkins; D W Marion; Jun Chen; R L Hamilton; JE Loeffert; Steven H Graham
Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(8):813-21.
1999: Michael J Whalen; Timothy M Carlos; C Edward Dixon; Joanne K Schiding; Robert S B Clark; E Baum; Hong Qu Yan; Donald W Marion; Patrick M Kochanek
Effect of traumatic brain injury in mice deficient in intercellular adhesion molecule-1: assessment of histopathologic and functional outcome.
Journal of neurotrauma 1999;16(4):299-309.
1999: Michael J Bell; Patrick M Kochanek; Melvyn P Heyes; Stephen R Wisniewski; EH Sinz; Robert S B Clark; Andrew R Blight; Donald W Marion; P David Adelson
Quinolinic acid in the cerebrospinal fluid of children after traumatic brain injury.
Critical care medicine 1999;27(3):493-7.
1999: C Edward Dixon; Patrick M Kochanek; Hong Qu Yan; Joanne K Schiding; R G Griffith; E Baum; Donald W Marion; Steven T DeKosky
One-year study of spatial memory performance, brain morphology, and cholinergic markers after moderate controlled cortical impact in rats.
Journal of neurotrauma 1999;16(2):109-22.
1998: Michael J Whalen; Timothy M Carlos; Patrick M Kochanek; Stephen R Wisniewski; Michael J Bell; Joseph A Carcillo; Robert S B Clark; Steven T DeKosky; P David Adelson
Soluble adhesion molecules in CSF are increased in children with severe head injury.
Journal of neurotrauma 1998;15(10):777-87.
1998: Peter Safar; N Bircher; Ernesto Pretto; P Berkebile; Samuel A Tisherman; D Marion; Miroslav Klain; Patrick M Kochanek
Reappraisal of mouth-to-mouth ventilation during bystander-initiated CPR.
Circulation 1998;98(6):608-10.
1998: L Zou; Lynn A Burmeister; Scot D Styren; Patrick M Kochanek; Steven T DeKosky
Up-regulation of type 2 iodothyronine deiodinase mRNA in reactive astrocytes following traumatic brain injury in the rat.
Journal of neurochemistry 1998;71(2):887-90.
1998: EH Sinz; Patrick M Kochanek; Melvyn P Heyes; Stephen R Wisniewski; Michael J Bell; Robert S B Clark; Steven T DeKosky; Andrew R Blight; Donald W Marion
Quinolinic acid is increased in CSF and associated with mortality after traumatic brain injury in humans.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(6):610-5.
1998: Laurence M Katz; Clifton Callaway; Valerian E Kagan; Patrick M Kochanek
Electron spin resonance measure of brain antioxidant activity during ischemia/reperfusion.
Neuroreport 1998;9(7):1587-93.
1998: Minzhi Chen; Robert S B Clark; Patrick M Kochanek; Jun Chen; Joanne K Schiding; R Anne Stetler; Roger P. Simon; Steven H Graham
72-kDa heat shock protein and mRNA expression after controlled cortical impact injury with hypoxemia in rats.
Journal of neurotrauma 1998;15(3):171-81.
1998: Michael J Bell; Patrick M Kochanek; Joseph A Carcillo; Zaichuan Mi; Joanne K Schiding; Stephen R Wisniewski; Robert S B Clark; C Edward Dixon; Donald W Marion; E Jackson
Interstitial adenosine, inosine, and hypoxanthine are increased after experimental traumatic brain injury in the rat.
Journal of neurotrauma 1998;15(3):163-70.
1998: MICHAEL LEIGHTON FORBES; Robert S B Clark; C Edward Dixon; Steven H Graham; Donald W Marion; Steven T DeKosky; Joanne K Schiding; Patrick M Kochanek
Augmented neuronal death in CA3 hippocampus following hyperventilation early after controlled cortical impact.
Journal of neurosurgery 1998;88(3):549-56.
1998: James R Goss; Mark E O'Malley; L Zou; Scot D Styren; Patrick M Kochanek; Steven T DeKosky
Astrocytes are the major source of nerve growth factor upregulation following traumatic brain injury in the rat.
Experimental neurology 1998;149(2):301-9.
1998: Michael J Whalen; Timothy M Carlos; Patrick M Kochanek; S Heineman
Blood-brain barrier permeability, neutrophil accumulation and vascular adhesion molecule expression after controlled cortical impact in rats: a preliminary study.
Acta neurochirurgica. Supplement 1998;71():212-4.
1998: P David Adelson; Michael J Whalen; Patrick M Kochanek; P Robichaud; Timothy M Carlos
Blood brain barrier permeability and acute inflammation in two models of traumatic brain injury in the immature rat: a preliminary report.
Acta neurochirurgica. Supplement 1998;71():104-6.
1998: Peter Safar; N Bircher; Ernesto Pretto; P Berkebile; Samuel A Tisherman; D Marion; Miroslav Klain; Patrick M Kochanek
A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation.
Resuscitation 1998;36(1):75-6; author reply 76-8.
1998: P David Adelson; Patrick M Kochanek
Head injury in children.
Journal of child neurology 1998;13(1):2-15.
1997: Robert S B Clark; Joseph A Carcillo; Patrick M Kochanek; Walter Obrist; Edwin K Jackson; Zaichuan Mi; S R Wisneiwski; Michael J Bell; Donald W Marion
Cerebrospinal fluid adenosine concentration and uncoupling of cerebral blood flow and oxidative metabolism after severe head injury in humans.
Neurosurgery 1997;41(6):1284-92; discussion 1292-3.
1997: Robert S B Clark; Jun Chen; simon simon watkins; Patrick M Kochanek; Minzhi Chen; R Anne Stetler; JE Loeffert; Steven H Graham
Apoptosis-suppressor gene bcl-2 expression after traumatic brain injury in rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(23):9172-82.
1997: Michael J Whalen; Timothy M Carlos; Robert S B Clark; Donald W Marion; Steven T DeKosky; S Heineman; Joanne K Schiding; F Memarzadeh; Patrick M Kochanek
The effect of brain temperature on acute inflammation after traumatic brain injury in rats.
Journal of neurotrauma 1997;14(8):561-72.
1997: MICHAEL LEIGHTON FORBES; Kristy S Hendrich; Patrick M Kochanek; Donald S Williams; Joanne K Schiding; Stephen R Wisniewski; S F Kelsey; Steven T DeKosky; Steven H Graham; Donald W Marion; Chien Ho
Assessment of cerebral blood flow and CO2 reactivity after controlled cortical impact by perfusion magnetic resonance imaging using arterial spin-labeling in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(8):865-74.
1997: Michael J Bell; Patrick M Kochanek; Lesley A Doughty; Joseph A Carcillo; P David Adelson; Robert S B Clark; Stephen R Wisniewski; Michael J Whalen; Steven T DeKosky
Interleukin-6 and interleukin-10 in cerebrospinal fluid after severe traumatic brain injury in children.
Journal of neurotrauma 1997;14(7):451-7.
1997: James R Goss; Kevin M Taffe; Patrick M Kochanek; Steven T DeKosky
The antioxidant enzymes glutathione peroxidase and catalase increase following traumatic brain injury in the rat.
Experimental neurology 1997;146(1):291-4.
1997: P David Adelson; BL Clyde; Patrick M Kochanek; S R Wisniewski; D W Marion; H Yonas
Cerebrovascular response in infants and young children following severe traumatic brain injury: a preliminary report.
Pediatric neurosurgery 1997;26(4):200-7.
1997: Robert S B Clark; Patrick M Kochanek; C Edward Dixon; Minzhi Chen; Donald W Marion; S Heineman; Steven T DeKosky; Steven H Graham
Early neuropathologic effects of mild or moderate hypoxemia after controlled cortical impact injury in rats.
Journal of neurotrauma 1997;14(4):179-89.
1997: Timothy M Carlos; Robert S B Clark; D Franicola-Higgins; Joanne K Schiding; Patrick M Kochanek
Expression of endothelial adhesion molecules and recruitment of neutrophils after traumatic brain injury in rats.
Journal of leukocyte biology 1997;61(3):279-85.
1997: Donald W Marion; Louis E Penrod; Sheryl F Kelsey; Walter Obrist; Patrick M Kochanek; Alan M Palmer; Stephen R Wisniewski; Steven T DeKosky
Treatment of traumatic brain injury with moderate hypothermia.
The New England journal of medicine 1997;336(8):540-6.
1997: P David Adelson; C Edward Dixon; P Robichaud; Patrick M Kochanek
Motor and cognitive functional deficits following diffuse traumatic brain injury in the immature rat.
Journal of neurotrauma 1997;14(2):99-108.
1997: Michael J Whalen; Timothy M Carlos; Robert S B Clark; Donald W Marion; M S DeKosky; S Heineman; Joanne K Schiding; F Memarzadeh; C Edward Dixon; Patrick M Kochanek
The relationship between brain temperature and neutrophil accumulation after traumatic brain injury in rats.
Acta neurochirurgica. Supplement 1997;70():260-1.
1997: Patrick M Kochanek; Robert S B Clark; Walter Obrist; Joseph A Carcillo; Edwin K Jackson; Zaichuan Mi; Stephen R Wisniewski; Michael J Bell; Donald W Marion
The role of adenosine during the period of delayed cerebral swelling after severe traumatic brain injury in humans.
Acta neurochirurgica. Supplement 1997;70():109-11.
1997: Michael J Bell; Patrick M Kochanek; Lesley A Doughty; Joseph A Carcillo; P David Adelson; Robert S B Clark; Michael J Whalen; Steven T DeKosky
Comparison of the interleukin-6 and interleukin-10 response in children after severe traumatic brain injury or septic shock.
Acta neurochirurgica. Supplement 1997;70():96-7.
1997: MICHAEL LEIGHTON FORBES; Kristy S Hendrich; Joanne K Schiding; Donald S Williams; Chien Ho; Steven T DeKosky; Donald W Marion; Patrick M Kochanek
Perfusion MRI assessment of cerebral blood flow and CO2 reactivity after controlled cortical impact in rats.
Advances in experimental medicine and biology 1997;411():7-12.
1996: P David Adelson; P Robichaud; R L Hamilton; Patrick M Kochanek
A model of diffuse traumatic brain injury in the immature rat.
Journal of neurosurgery 1996;85(5):877-84.
1996: Robert S B Clark; Patrick M Kochanek; Walter Obrist; H R Wong; Timothy R Billiar; Stephen R Wisniewski; Donald W Marion
Cerebrospinal fluid and plasma nitrite and nitrate concentrations after head injury in humans.
Critical care medicine 1996;24(7):1243-51.
1996: Robert S B Clark; Timothy M Carlos; Joanne K Schiding; M Bree; L A Fireman; Steven T DeKosky; Patrick M Kochanek
Antibodies against Mac-1 attenuate neutrophil accumulation after traumatic brain injury in rats.
Journal of neurotrauma 1996;13(6):333-41.
1996: Robert S B Clark; Patrick M Kochanek; M A Schwarz; Joanne K Schiding; D S Turner; M Chen; Timothy M Carlos; simon simon watkins
Inducible nitric oxide synthase expression in cerebrovascular smooth muscle and neutrophils after traumatic brain injury in immature rats.
Pediatric research 1996;39(5):784-90.
1996: K V Biagas; P D Grundl; Patrick M Kochanek; Joanne K Schiding; Edwin M Nemoto
Posttraumatic hyperemia in immature, mature, and aged rats: autoradiographic determination of cerebral blood flow.
Journal of neurotrauma 1996;13(4):189-200.
1996: Robert S B Clark; Patrick M Kochanek; Donald W Marion; Joanne K Schiding; M White; Alan Palmer; Steven T DeKosky
Mild posttraumatic hypothermia reduces mortality after severe controlled cortical impact in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(2):253-61.
1996: R T Mansfield; Joanne K Schiding; R L Hamilton; Patrick M Kochanek
Effects of hypothermia on traumatic brain injury in immature rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(2):244-52.
1996: Uwe Ebmeyer; Laurence M Katz; Peter Safar; N Bircher; Samuel A Tisherman; Ernesto Pretto; Miroslav Klain; Patrick M Kochanek
Concluding comments and suggestions for young resuscitation researchers.
Critical care medicine 1996;24(2 Suppl):S95-9.
1996: Donald W Marion; Y Leonov; Myron D Ginsberg; Laurence M Katz; Patrick M Kochanek; A Lechleuthner; Edwin M Nemoto; Walter Obrist; Peter Safar; F Sterz; Samuel A Tisherman; R J White; F Xiao; Harvey Zar
Resuscitative hypothermia.
Critical care medicine 1996;24(2 Suppl):S81-9.
1996: S E Gisvold; F Sterz; N S Abramson; Gad Bar-Joseph; Uwe Ebmeyer; H Gervais; Myron D Ginsberg; Laurence M Katz; Patrick M Kochanek; K Kuboyama; B Miller; Walter Obrist; Risto Roine; Peter Safar; K M Sim; K Vandevelde; R J White; F Xiao
Cerebral resuscitation from cardiac arrest: treatment potentials.
Critical care medicine 1996;24(2 Suppl):S69-80.
1996: H L Rosomoff; Patrick M Kochanek; R Clark; Steven T DeKosky; Uwe Ebmeyer; Ake Grenvik; Donald W Marion; Walter Obrist; Alan Palmer; P Safer; R J White
Resuscitation from severe brain trauma.
Critical care medicine 1996;24(2 Suppl):S48-56.
1996: R Bellamy; Peter Safar; Samuel A Tisherman; R Basford; S P Bruttig; A Capone; Michael A Dubick; L Ernster; B G Hattler; P Hochachka; Miroslav Klain; Patrick M Kochanek; W A Kofke; JR Lancaster; Francis X McGowan; P R Oeltgen; J W Severinghaus; M J Taylor; Harvey Zar
Suspended animation for delayed resuscitation.
Critical care medicine 1996;24(2 Suppl):S24-47.
1996: Steven T DeKosky; Scot D Styren; Mark E O'Malley; James R Goss; Patrick M Kochanek; D Marion; Christopher H Evans; Paul D Robbins
Interleukin-1 receptor antagonist suppresses neurotrophin response in injured rat brain.
Annals of neurology 1996;39(1):123-7.
1995: Patrick M Kochanek; Donald W Marion; W Zhang; Joanne K Schiding; M White; Alan Palmer; Robert S B Clark; Mark E O'Malley; Scot D Styren; C Ho
Severe controlled cortical impact in rats: assessment of cerebral edema, blood flow, and contusion volume.
Journal of neurotrauma 1995;12(6):1015-25.
1995: S L Kaczorowski; Joanne K Schiding; C A Toth; Patrick M Kochanek
Effect of soluble complement receptor-1 on neutrophil accumulation after traumatic brain injury in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(5):860-4.
1995: James R Goss; Scot D Styren; P D Miller; Patrick M Kochanek; Alan Palmer; Donald W Marion; Steven T DeKosky
Hypothermia attenuates the normal increase in interleukin 1 beta RNA and nerve growth factor following traumatic brain injury in the rat.
Journal of neurotrauma 1995;12(2):159-67.
1994: Steven T DeKosky; James R Goss; P D Miller; Scot D Styren; Patrick M Kochanek; D Marion
Upregulation of nerve growth factor following cortical trauma.
Experimental neurology 1994;130(2):173-7.
1994: A Morton; H Dalton; Patrick M Kochanek; J Janosky; A Thompson
Extracorporeal membrane oxygenation for pediatric respiratory failure: five-year experience at the University of Pittsburgh.
Critical care medicine 1994;22(10):1659-67.
1994: Robert S B Clark; Joanne K Schiding; S L Kaczorowski; Donald W Marion; Patrick M Kochanek
Neutrophil accumulation after traumatic brain injury in rats: comparison of weight drop and controlled cortical impact models.
Journal of neurotrauma 1994;11(5):499-506.
1994: M W Uhl; K V Biagas; P D Grundl; MA Barmada; Joanne K Schiding; Edwin M Nemoto; Patrick M Kochanek
Effects of neutropenia on edema, histology, and cerebral blood flow after traumatic brain injury in rats.
Journal of neurotrauma 1994;11(3):303-15.
1994: P D Grundl; K V Biagas; Patrick M Kochanek; Joanne K Schiding; MA Barmada; Edwin M Nemoto
Early cerebrovascular response to head injury in immature and mature rats.
Journal of neurotrauma 1994;11(2):135-48.
1993: M W Uhl; Patrick M Kochanek; Joanne K Schiding; Edwin M Nemoto
Effect of phorbol myristate acetate on cerebral blood flow in normal and neutrophil-depleted rats.
Stroke; a journal of cerebral circulation 1993;24(12):1977-82.
1993: Patrick M Kochanek
Ischemic and traumatic brain injury: pathobiology and cellular mechanisms.
Critical care medicine 1993;21(9 Suppl):S333-5.
1993: J J Zimmerman; Patrick M Kochanek; W Meadow; M M Mariscalco
Molecular pathophysiology in critical care illness.
Critical care medicine 1993;21(9 Suppl):S400.
1992: Patrick M Kochanek; J M Hallenbeck
Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke.
Stroke; a journal of cerebral circulation 1992;23(9):1367-79.
1992: N C Singh; Patrick M Kochanek; Joanne K Schiding; J A Melick; Edwin M Nemoto
Uncoupled cerebral blood flow and metabolism after severe global ischemia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(5):802-8.
1992: K V Biagas; M W Uhl; Joanne K Schiding; Edwin M Nemoto; Patrick M Kochanek
Assessment of posttraumatic polymorphonuclear leukocyte accumulation in rat brain using tissue myeloperoxidase assay and vinblastine treatment.
Journal of neurotrauma 1992;9(4):363-71.
1992: M W Uhl; Patrick M Kochanek; Joanne K Schiding; J A Melick; Edwin M Nemoto
The regional cerebral blood flow response to cortical microelectrode insertion is neutrophil dependent.
Advances in experimental medicine and biology 1992;317():701-5.
1991: Patrick M Kochanek; R Schoettle; M Uhl; M J Magargee; E Nemoto
Platelet-activating factor antagonists do not attenuate delayed posttraumatic cerebral edema in rats.
Journal of neurotrauma 1991;8(1):19-25.
1990: Patrick M Kochanek; J A Melick; R J Schoettle; M J Magargee; R W Evans; Edwin M Nemoto
Endogenous platelet activating factor does not modulate blood flow and metabolism in normal rat brain.
Stroke; a journal of cerebral circulation 1990;21(3):459-62.
1990: R J Schoettle; Patrick M Kochanek; M J Magargee; M W Uhl; Edwin M Nemoto
Early polymorphonuclear leukocyte accumulation correlates with the development of posttraumatic cerebral edema in rats.
Journal of neurotrauma 1990;7(4):207-17.
1990: Patrick M Kochanek; J A Melick; R J Schoettle; M J Magargee; R W Evans; Edwin M Nemoto
Platelet activating factor antagonists do not alter normal cerebral blood flow or cerebral oxygen consumption.
Advances in experimental medicine and biology 1990;277():345-51.
1988: A Trento; A Thompson; Ralph D Siewers; Richard A Orr; Patrick M Kochanek; Bradley P Fuhrman; J Frattallone; L B Beerman; D R Fischer; Bartley P Griffith
Extracorporeal membrane oxygenation in children. New trends.
The Journal of thoracic and cardiovascular surgery 1988;96(4):542-7.
1988: Patrick M Kochanek
Novel pharmacologic approaches to brain resuscitation after cardiorespiratory arrest in the pediatric patient.
Critical care clinics 1988;4(4):661-77.
1988: Patrick M Kochanek; Edwin M Nemoto; J A Melick; R W Evans; D F Burke
Cerebrovascular and cerebrometabolic effects of intracarotid infused platelet-activating factor in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1988;8(4):546-51.
1988: J M Frattallone; Bradley P Fuhrman; Patrick M Kochanek; Richard A Orr; Ralph D Siewers; A E Thompson; A Trento
Management of pulmonary barotrauma by extracorporeal membrane oxygenation, apnea, and lung rest.
The Journal of pediatrics 1988;112(5):787-9.