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Gerd Kochendoerfer

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Physiology

Protein Folding

Phenomena

Circular Dichroism

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Publications

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Les P Miranda; Haiyan Shao; Jason Williams; Shiah-Yun Chen; Ting Kong; Rod Garcia; Yvonne Chinn; Nathalie Fraud; Bill O'Dwyer; Jay Ye; Jill Wilken; Donald E Low; E Neil Cagle; Maia Carnevali; Alexander Lee; Di Song; Ada Kung; James A Bradburne; Xavier Paliard; Gerd G Kochendoerfer
A chemical approach to the pharmaceutical optimization of an anti-HIV protein.
Gerd G Kochendoerfer
Site-specific polymer modification of therapeutic proteins.
Gerd G Kochendoerfer; Daniel Clayton; Christian Becker
Chemical synthesis approaches to the engineering of ion channels.

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All Publications

2007: Les P Miranda; Haiyan Shao; Jason Williams; Shiah-Yun Chen; Ting Kong; Rod Garcia; Yvonne Chinn; Nathalie Fraud; Bill O'Dwyer; Jay Ye; Jill Wilken; Donald E Low; E Neil Cagle; Maia Carnevali; Alexander Lee; Di Song; Ada Kung; James A Bradburne; Xavier Paliard; Gerd G Kochendoerfer
A chemical approach to the pharmaceutical optimization of an anti-HIV protein.
Journal of the American Chemical Society 2007;129(43):13153-9.
2005: Gerd G Kochendoerfer
Site-specific polymer modification of therapeutic proteins.
Current opinion in chemical biology 2005;9(6):555-60.
2005: Gerd G Kochendoerfer; Daniel Clayton; Christian Becker
Chemical synthesis approaches to the engineering of ion channels.
Protein and peptide letters 2005;12(8):737-41.
2005: Shiah-Yun Chen; Sonya Cressman; Feng Mao; Haiyan Shao; Donald W Low; Hal S Beilan; E Neil Cagle; Maia Carnevali; Vincent Gueriguian; Peter J Keogh; Heather Porter; Stephen M Stratton; M Con Wiedeke; Laura Savatski; John W Adamson; Carlos E Bozzini; Ada Kung; Stephen B H Kent; James A Bradburne; Gerd G Kochendoerfer
Synthetic erythropoietic proteins: tuning biological performance by site-specific polymer attachment.
Chemistry & biology 2005;12(3):371-83.
2005: Haiyan Shao; Milan M Crnogorac; Ting Kong; Shiah-Yun Chen; Jason M Williams; Janette M Tack; Vincent Gueriguian; E Neil Cagle; Maia Carnevali; David Tumelty; Xavier Paliard; Les P Miranda; James A Bradburne; Gerd G Kochendoerfer
Site-specific polymer attachment to a CCL-5 (RANTES) analogue by oxime exchange.
Journal of the American Chemical Society 2005;127(5):1350-1.
2004: Christian F W Becker; Pavel Strop; Randal B Bass; Kirk Hansen; Kaspar P Locher; Gang Ren; Mark Yeager; Douglas C Rees; Gerd G Kochendoerfer
Conversion of a mechanosensitive channel protein from a membrane-embedded to a water-soluble form by covalent modification with amphiphiles.
Journal of molecular biology 2004;343(3):747-58.
2004: Christian F W Becker; Daniel Clayton; George Shapovalov; Henry A Lester; Gerd G Kochendoerfer
On-resin assembly of a linkerless lanthanide(III)-based luminescence label and its application to the total synthesis of site-specifically labeled mechanosensitive channels.
Bioconjugate chemistry 2004;15(5):1118-24.
2004: Christie L Hunter; Gerd G Kochendoerfer
Native chemical ligation of hydrophobic [corrected] peptides in lipid bilayer systems.
Bioconjugate chemistry 2004;15(3):437-40.
2004: Christian F W Becker; Myrta Oblatt-Montal; Gerd G Kochendoerfer; Mauricio Montal
Chemical synthesis and single channel properties of tetrameric and pentameric TASPs (template-assembled synthetic proteins) derived from the transmembrane domain of HIV virus protein u (Vpu).
The Journal of biological chemistry 2004;279(17):17483-9.
2004: Daniel Clayton; George Shapovalov; Joshua A Maurer; Dennis A Dougherty; Henry A Lester; Gerd G Kochendoerfer
Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4764-9.
2004: Gerd G Kochendoerfer; David H Jones; Sangwon Lee; Myrta Oblatt-Montal; Stanley J Opella; Mauricio Montal
Functional characterization and NMR spectroscopy on full-length Vpu from HIV-1 prepared by total chemical synthesis.
Journal of the American Chemical Society 2004;126(8):2439-46.
2003: Gerd G Kochendoerfer; Shiah-Yun Chen; Feng Mao; Sonya Cressman; Stacey Traviglia; Haiyan Shao; Christie L Hunter; Donald W Low; E Neil Cagle; Maia Carnevali; Vincent Gueriguian; Peter J Keogh; Heather Porter; Stephen M Stratton; M Con Wiedeke; Jill Wilken; Jie Tang; Jay J Levy; Les P Miranda; Milan M Crnogorac; Suresh Kalbag; Paolo Botti; Janice Schindler-Horvat; Laura Savatski; John W Adamson; Ada Kung; Stephen B H Kent; James A Bradburne
Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein.
Science (New York, N.Y.) 2003;299(5608):884-7.
2002: Gerd G Kochendoerfer; Janette M Tack; Sonya Cressman
Total chemical synthesis of a 27 kDa TASP protein derived from the MscL ion channel of M. tuberculosis by ketoxime-forming ligation.
Bioconjugate chemistry 2002;13(3):474-80.
2001: Gerd G Kochendoerfer
Chemical protein synthesis methods in drug discovery.
Current opinion in drug discovery & development 2001;4(2):205-14.
1999: Gerd G Kochendoerfer; Stephen B H Kent
Chemical protein synthesis.
Current opinion in chemical biology 1999;3(6):665-71.
1999: Gerd G Kochendoerfer; D Salom; James D Lear; R Wilk-Orescan; Stephen B H Kent; W F DeGrado
Total chemical synthesis of the integral membrane protein influenza A virus M2: role of its C-terminal domain in tetramer assembly.
Biochemistry 1999;38(37):11905-13.