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Jens Kockskämper

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Anatomy

Chemicals & Drugs

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M Sacherer; Simon Sedej; M Sereinigg; P Stiegler; Dirk von Lewinski; P Wakuła; M Wallner; F R Heinzel; Burkert Pieske; M A Vos; G Antoons; Jens Kockskämper
JTV519 (K201) reduces sarcoplasmic reticulum Ca²⁺ leak and improves diastolic function in vitro in murine and human non-failing myocardium.
Senka Ljubojević; Stefanie Walther; Mojib Asgarzoei; Simon Sedej; Burkert Pieske; Jens Kockskämper
In situ calibration of nucleoplasmic versus cytoplasmic Ca²+ concentration in adult cardiomyocytes.
Paulina Wakula; Egbert Bisping; Jens Kockskämper; Heiner Post; Sabine Brauer; Marion Deuter; Ralph Oehlmann; Urban Besenfelder; F Anthony Lai; Gottfried Brem; Burkert Pieske
CMV promoter is inadequate for expression of mutant human RyR2 in transgenic rabbits.

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All Publications

2012: M Sacherer; Simon Sedej; M Sereinigg; P Stiegler; Dirk von Lewinski; P Wakuła; M Wallner; F R Heinzel; Burkert Pieske; M A Vos; G Antoons; Jens Kockskämper
JTV519 (K201) reduces sarcoplasmic reticulum Ca²⁺ leak and improves diastolic function in vitro in murine and human non-failing myocardium.
British journal of pharmacology 2012;167(3):493-504.
2011: Senka Ljubojević; Stefanie Walther; Mojib Asgarzoei; Simon Sedej; Burkert Pieske; Jens Kockskämper
In situ calibration of nucleoplasmic versus cytoplasmic Ca²+ concentration in adult cardiomyocytes.
Biophysical journal 2011;100(10):2356-66.
2011: Paulina Wakula; Egbert Bisping; Jens Kockskämper; Heiner Post; Sabine Brauer; Marion Deuter; Ralph Oehlmann; Urban Besenfelder; F Anthony Lai; Gottfried Brem; Burkert Pieske
CMV promoter is inadequate for expression of mutant human RyR2 in transgenic rabbits.
Journal of pharmacological and toxicological methods 2011;63(2):180-5.
2011: Nataliya Dybkova; Simon Sedej; Carlo Napolitano; Stefan Neef; Adam G Rokita; Mark Hünlich; Joan Heller Brown; Jens Kockskämper; Silvia G Priori; Burkert Pieske; Lars S Maier
Overexpression of CaMKIIδc in RyR2R4496C+/- knock-in mice leads to altered intracellular Ca2+ handling and increased mortality.
Journal of the American College of Cardiology 2011;57(4):469-79.
2011: Li-Zhen Yang; Jens Kockskämper; Shelina Khan; Jorge Suarez; Stefanie Walther; Bernhard Doleschal; Gregor Unterer; Mounir Khafaga; Heinrich Mächler; Frank R Heinzel; Wolfgang H Dillmann; Burkert Pieske; Joachim Spiess
cAMP- and Ca²(+) /calmodulin-dependent protein kinases mediate inotropic, lusitropic and arrhythmogenic effects of urocortin 2 in mouse ventricular myocytes.
British journal of pharmacology 2011;162(2):544-56.
2010: Simon Sedej; Frank R Heinzel; Stefanie Walther; Nataliya Dybkova; Paulina Wakula; Jan Groborz; Phillip Gronau; Lars S Maier; Marc A Vos; F Anthony Lai; Carlo Napolitano; Silvia G Priori; Jens Kockskämper; Burkert Pieske
Na+-dependent SR Ca2+ overload induces arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation.
Cardiovascular research 2010;87(1):50-9.
2010: Li-Zhen Yang; Philip Tovote; Martin Rayner; Jens Kockskämper; Burkert Pieske; Joachim Spiess
Corticotropin-releasing factor receptors and urocortins, links between the brain and the heart.
European journal of pharmacology 2010;632(1-3):1-6.
2009: Lennart Suckau; Henry Fechner; Elie Chemaly; Stefanie Krohn; Lahouaria Hadri; Jens Kockskämper; Dirk Westermann; Egbert Bisping; Hung Ly; Xiaomin Wang; Yoshiaki Kawase; Jiqiu Chen; Lifan Liang; Isaac Sipo; Roland Vetter; Stefan Weger; Jens Kurreck; Volker Erdmann; Carsten Tschope; Burkert Pieske; Djamel Lebeche; Heinz-Peter Schultheiss; Roger J Hajjar; Wolfgang Poller
Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy.
Circulation 2009;119(9):1241-52.
2009: Dirk von Lewinski; Jens Kockskämper; Danan Zhu; Heiner Post; Andreas Elgner; Burkert Pieske
Reduced stretch-induced force response in failing human myocardium caused by impaired Na(+)-contraction coupling.
Circulation. Heart failure 2009;2(1):47-55.
2008: Dirk von Lewinski; Jens Kockskämper; Sven-Ulrich Rübertus; Danan Zhu; Jan Schmitto; Friedrich A Schöndube; Gerd Hasenfuss; Burkert Pieske
Direct pro-arrhythmogenic effects of angiotensin II can be suppressed by AT1 receptor blockade in human atrial myocardium.
European journal of heart failure 2008;10(12):1172-6.
2008: Jens Kockskämper; Mounir Khafaga; Michael Grimm; Andreas Elgner; Stefanie Walther; Anke Kockskämper; Dirk von Lewinski; Heiner Post; Marius Grossmann; Hilmar Dörge; Philip A Gottlieb; Frederick Sachs; Thomas Eschenhagen; Friedrich A Schöndube; Burkert Pieske
Angiotensin II and myosin light-chain phosphorylation contribute to the stretch-induced slow force response in human atrial myocardium.
Cardiovascular research 2008;79(4):642-51.
2008: Jens Kockskämper; Aleksey V Zima; H Llewelyn Roderick; Burkert Pieske; Lothar A Blatter; Martin D Bootman
Emerging roles of inositol 1,4,5-trisphosphate signaling in cardiac myocytes.
Journal of molecular and cellular cardiology 2008;45(2):128-47.
2008: Jens Kockskämper; Dirk von Lewinski; Mounir Khafaga; Andreas Elgner; Michael Grimm; Thomas Eschenhagen; Philip A Gottlieb; Frederick Sachs; Burkert Pieske
The slow force response to stretch in atrial and ventricular myocardium from human heart: functional relevance and subcellular mechanisms.
Progress in biophysics and molecular biology 2008;97(2-3):250-67.
2008: Jens Kockskämper; Lea Seidlmayer; Stefanie Walther; Kristian Hellenkamp; Lars S Maier; Burkert Pieske
Endothelin-1 enhances nuclear Ca2+ transients in atrial myocytes through Ins(1,4,5)P3-dependent Ca2+ release from perinuclear Ca2+ stores.
Journal of cell science 2008;121(Pt 2):186-95.
2007: Dirk von Lewinski; Egbert Bisping; Andreas Elgner; Jens Kockskämper; Burkert Pieske
Mechanistic insight into the functional and toxic effects of Strophanthidin in the failing human myocardium.
European journal of heart failure 2007;9(11):1086-94.
2007: Wolfgang Schillinger; Nils Teucher; Samuel Sossalla; Sarah Kettlewell; Carola Werner; Dirk Raddatz; Andreas Elgner; Gero Tenderich; Burkert Pieske; Giuliano Ramadori; Friedrich A Schöndube; Harald Kögler; Jens Kockskämper; Lars S Maier; Harald Schwörer; Godfrey L Smith; Gerd Hasenfuss
Negative inotropy of the gastric proton pump inhibitor pantoprazole in myocardium from humans and rabbits: evaluation of mechanisms.
Circulation 2007;116(1):57-66.
2006: Aleksey V Zima; Jens Kockskämper; Lothar A Blatter
Cytosolic energy reserves determine the effect of glycolytic sugar phosphates on sarcoplasmic reticulum Ca2+ release in cat ventricular myocytes.
The Journal of physiology 2006;577(Pt 1):281-93.
2006: Jens Kockskämper; Burkert Pieske
Phosphorylation of the cardiac ryanodine receptor by Ca2+/calmodulin-dependent protein kinase II: the dominating twin of protein kinase A?
Circulation research 2006;99(4):333-5.
2006: Li-Zhen Yang; Jens Kockskämper; Frank R Heinzel; Michael Hauber; Stefanie Walther; Joachim Spiess; Burkert Pieske
Urocortin II enhances contractility in rabbit ventricular myocytes via CRF(2) receptor-mediated stimulation of protein kinase A.
Cardiovascular research 2006;69(2):402-11.
2005: Claus Luers; Florian Fialka; Andreas Elgner; Danan Zhu; Jens Kockskämper; Dirk von Lewinski; Burkert Pieske
Stretch-dependent modulation of [Na+]i, [Ca2+]i, and pHi in rabbit myocardium--a mechanism for the slow force response.
Cardiovascular research 2005;68(3):454-63.
2005: Jens Kockskämper; Aleksey V Zima; Lothar A Blatter
Modulation of sarcoplasmic reticulum Ca2+ release by glycolysis in cat atrial myocytes.
The Journal of physiology 2005;564(Pt 3):697-714.
2004: Sanda Despa; Jens Kockskämper; Lothar A Blatter; Donald M Bers
Na/K pump-induced [Na](i) gradients in rat ventricular myocytes measured with two-photon microscopy.
Biophysical journal 2004;87(2):1360-8.
2004: Jens Kockskämper; Gias Ahmmed; Aleksey V Zima; Katherine Sheehan; Helfried G Glitsch; Lothar A Blatter
Palytoxin disrupts cardiac excitation-contraction coupling through interactions with P-type ion pumps.
American journal of physiology. Cell physiology 2004;287(2):C527-38.
2003: Aleksey V Zima; Jens Kockskämper; Rafael Mejia-Alvarez; Lothar A Blatter
Pyruvate modulates cardiac sarcoplasmic reticulum Ca2+ release in rats via mitochondria-dependent and -independent mechanisms.
The Journal of physiology 2003;550(Pt 3):765-83.
2003: Lothar A Blatter; Jens Kockskämper; Katherine Sheehan; Aleksey V Zima; Jörg Hüser; Stephen L Lipsius
Local calcium gradients during excitation-contraction coupling and alternans in atrial myocytes.
The Journal of physiology 2003;546(Pt 1):19-31.
2002: Jens Kockskämper; Lothar A Blatter
Subcellular Ca2+ alternans represents a novel mechanism for the generation of arrhythmogenic Ca2+ waves in cat atrial myocytes.
The Journal of physiology 2002;545(Pt 1):65-79.
2002: Burkert Pieske; Jens Kockskämper
Alternans goes subcellular: a "disease" of the ryanodine receptor?
Circulation research 2002;91(7):553-5.
2002: Simone Erlenkamp; Helfried G Glitsch; Jens Kockskämper
Dual regulation of cardiac Na+-K+ pumps and CFTR Cl- channels by protein kinases A and C.
Pflügers Archiv : European journal of physiology 2002;444(1-2):251-62.
2001: Jens Kockskämper; Katherine Sheehan; Dan J Bare; Stephen L Lipsius; Gregory A Mignery; Lothar A Blatter
Activation and propagation of Ca(2+) release during excitation-contraction coupling in atrial myocytes.
Biophysical journal 2001;81(5):2590-605.
2001: Jens Kockskämper; K Sendhoff; Simone Erlenkamp; Frank Bordusa; V Cerovsky; Helfried G Glitsch
Differences in the protein-kinase-A-dependent regulation of CFTR Cl- channels and Na+-K+ pumps in guinea-pig ventricular myocytes.
Pflügers Archiv : European journal of physiology 2001;441(6):807-15.
2000: V Cerovský; Jens Kockskämper; Helfried G Glitsch; Frank Bordusa
Semisynthesis of Ht31(493--515): involvement of PKA-anchoring proteins in the regulation of the cAMP-dependent chloride current in heart cells.
Chembiochem : a European journal of chemical biology 2000;1(2):126-9.
1999: G Barmashenko; Jens Kockskämper; Helfried G Glitsch
Depolarization increases the apparent affinity of the Na+-K+ pump to cytoplasmic Na+ in isolated guinea-pig ventricular myocytes.
The Journal of physiology 1999;517 ( Pt 3)():691-8.
1998: M Traebert; I Trebess; Simone Erlenkamp; Jörg Hüser; Jens Kockskämper; Helfried G Glitsch; C Hartung; Peter Welzel
High affinity regulation of cardiac Cl- and Ca2+ conductances by (13R)-spiroforskolin.
Naunyn-Schmiedeberg's archives of pharmacology 1998;358(5):538-46.
1997: Jens Kockskämper; Helfried G Glitsch
Sodium pump of cultured guinea pig atrial myocytes.
Annals of the New York Academy of Sciences 1997;834():354-6.
1997: Jens Kockskämper; Günter Gisselmann; Helfried G Glitsch
Comparison of ouabain-sensitive and -insensitive Na/K pumps in HEK293 cells.
Biochimica et biophysica acta 1997;1325(2):197-208.