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Dirk Koczan

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Tomas Fiedler; Dirk Koczan; Bernd Kreikemeyer; Catur Riani; Kerstin Standar; Andreas Podbielski
Protective mechanisms of respiratory tract Streptococci against Streptococcus pyogenes biofilm formation and epithelial cell infection.
Dariusz Leszczynski; Dieter Stoll; David de Pomerai; Helmut Franke; Dirk Koczan; Juan Pablo Albar
Five years later: the current status of the use of proteomics and transcriptomics in EMF research.
Charlotte Angerstein; Michael Hecker; Dirk Koczan; Brigitte Katrin Paap; Madhan Thamilarasan; Hans-Jürgen Thiesen; Uwe Klaus Zettl
Integration of MicroRNA databases to study MicroRNAs associated with multiple sclerosis.

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2013: Tomas Fiedler; Dirk Koczan; Bernd Kreikemeyer; Catur Riani; Kerstin Standar; Andreas Podbielski
Protective mechanisms of respiratory tract Streptococci against Streptococcus pyogenes biofilm formation and epithelial cell infection.
Applied and environmental microbiology 2013;79(4):1265-76.
2012: Dariusz Leszczynski; Dieter Stoll; David de Pomerai; Helmut Franke; Dirk Koczan; Juan Pablo Albar
Five years later: the current status of the use of proteomics and transcriptomics in EMF research.
Proteomics 2012;12(15-16):2493-509.
2012: Charlotte Angerstein; Michael Hecker; Dirk Koczan; Brigitte Katrin Paap; Madhan Thamilarasan; Hans-Jürgen Thiesen; Uwe Klaus Zettl
Integration of MicroRNA databases to study MicroRNAs associated with multiple sclerosis.
Molecular neurobiology 2012;45(3):520-35.
2012: Ludwig G Strauss; Jochen Tuettenberg; Caixia Cheng; Dirk Koczan; Leyun Pan; Kirsten Schmieder; Marcel Seiz; Antonia Dimitrakopoulou-Strauss
Correlation of the Ga-68-bombesin analog Ga-68-BZH3 with receptors expression in gliomas as measured by quantitative dynamic positron emission tomography (dPET) and gene arrays.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2012;14(3):376-83.
2012: Alexander Hundeshagen; Ole Kandulski; Dirk Koczan; Brigitte Katrin Paap; Hans-Juergen Thiesen; Charlotte Angerstein; Christian Fatum; Christiane Hartmann; Michael Hecker; Uwe Klaus Zettl
Elevated type I interferon-like activity in a subset of multiple sclerosis patients: molecular basis and clinical relevance.
Journal of neuroinflammation 2012;9():140.
2012: Ludwig G Strauss; Antonia Dimitrakopoulou-Strauss; Dirk Koczan; Leyun Pan; Peter Hohenberger
Correlation of dynamic PET and gene array data in patients with gastrointestinal stromal tumors.
TheScientificWorldJournal 2012;2012():721313.
2012: Peter Kupfer; Dirk Pohlers; Reinhard Guthke; Rene Huber; Dirk Koczan; Raimund W Kinne
Batch correction of microarray data substantially improves the identification of genes differentially expressed in rheumatoid arthritis and osteoarthritis.
BMC medical genomics 2012;5():23.
2012: Juliane Günther; Dirk Koczan; Wolfram Petzl; Hans-Joachim Schuberth; Leopold Goetze; Holm Zerbe; Hans-Martin Seyfert
Lipopolysaccharide priming enhances expression of effectors of immune defence while decreasing expression of pro-inflammatory cytokines in mammary epithelia cells from cows.
BMC genomics 2012;13():17.
2012: Madhan Thamilarasan; Michael Hecker; Dirk Koczan; Brigitte Paap; Uwe K Zettl
MicroRNAs in multiple sclerosis and experimental autoimmune encephalomyelitis.
Autoimmunity reviews 2012;11(3):174-9.
2011: Orianne Mazemondet; Arndt Rolfs; Adelinde M Uhrmacher; Dieter G Weiss; Benjamin M Bader; Jana Frahm; Moritz J Frech; Rayk Hubner; Dirk Koczan; Jiankai Luo
Quantitative and kinetic profile of Wnt/β-catenin signaling components during human neural progenitor cell differentiation.
Cellular & molecular biology letters 2011;16(4):515-38.
2011: Jens Vanselow; Charlotte Rehfeldt; Dirk Koczan; Marzena Kucia; Martina Langhammer; Cornelia C Metges
Hepatic expression of the GH/JAK/STAT/IGF pathway, acute-phase response signalling and complement system are affected in mouse offspring by prenatal and early postnatal exposure to maternal high-protein diet.
European journal of nutrition 2011;50(8):611-23.
2011: Ludwig G. Strauss; Stefan Willis; Caixia Cheng; Uwe Haberkorn; Sven Klippel; Dirk Koczan; Leyun Pan; Antonia Dimitrakopoulou-Strauss
Impact of cell-proliferation-associated gene expression on 2-deoxy-2-[(18)f]fluoro-D-glucose (FDG) kinetics as measured by dynamic positron emission tomography (dPET) in colorectal tumors.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2011;13(6):1290-300.
2011: Christian Schwerk; Barbara Spellerberg; Carolin Stump; Tobias Tenenbaum; Sascha Zink; Rüdiger Adam; Julia Borkowski; Ludger Klein-Hitpass; Michael Klenk; Dirk Koczan; Natascha Quednau; Anubha Sagar; Nicole Schmidt; Henriette Schneider; Horst Schroten
In vitro transcriptome analysis of porcine choroid plexus epithelial cells in response to Streptococcus suis: release of pro-inflammatory cytokines and chemokines.
Microbes and infection / Institut Pasteur 2011;13(11):953-62.
2011: Ivonne Loeffler; Ulrike Hopfer; Dirk Koczan; Gunter Wolf
Type VIII collagen modulates TGF-β1-induced proliferation of mesangial cells.
Journal of the American Society of Nephrology : JASN 2011;22(4):649-63.
2010: J-Matthias Löhr; Ralf Faissner; Dirk Koczan; Peter Bewerunge; Claudio Bassi; Benedikt Brors; Roland Eils; Luca Frulloni; Anette Funk; Walter Halangk; Ralf Jesnowski; Lars Kaderali; Jörg Kleeff; Burkhard Krüger; Markus M Lerch; Ralf Lösel; Mauro Magnani; Michael Neumaier; Stephanie Nittka; Miklós Sahin-Tóth; Julian Sänger; Sonja Serafini; Martina Schnölzer; Hermann-Josef Thierse; Silke Wandschneider; GIUSEPPE ZAMBONI; Ralf Jesenofsky; Günter Klöppel
Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process.
The American journal of gastroenterology 2010;105(9):2060-71.
2010: Martin Skiba; Frithjof Glowinski; Dirk Koczan; Thomas C Mettenleiter; Axel Karger
Gene expression profiling of Pseudorabies virus (PrV) infected bovine cells by combination of transcript analysis and quantitative proteomic techniques.
Veterinary microbiology 2010;143(1):14-20.
2010: Julia Schultz; Dirk Koczan; Ulf Schmitz; Saleh M Ibrahim; Dominik Pilch; Jenny Landsberg; Manfred Kunz
Tumor-promoting role of signal transducer and activator of transcription (Stat)1 in late-stage melanoma growth.
Clinical & experimental metastasis 2010;27(3):133-40.
2010: Gisela Sparmann; Marie-Luise Kruse; Nicole Hofmeister-Mielke; Dirk Koczan; Robert Jaster; Stefan Liebe; Daniel Wolff; Jörg Emmrich
Bone marrow-derived pancreatic stellate cells in rats.
Cell research 2010;20(3):288-98.
2010: Pablo Serrano-Fernández; Steffen Möller; Robert Goertsches; H Fiedler; Dirk Koczan; Hans-Jürgen Thiesen; Uwe K Zettl
Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis.
Autoimmunity 2010;43(2):172-8.
2010: Robert H Goertsches; Michael Hecker; Dirk Koczan; Pablo Serrano-Fernandez; Steffen Moeller; Hans-Jürgen Thiesen; Uwe K Zettl
Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-beta-1b treatment in relapsing remitting MS.
Pharmacogenomics 2010;11(2):147-61.
2010: Vijay Alla; David Engelmann; Annett Niemetz; Jens Pahnke; Anke Schmidt; Manfred Kunz; Stephan Emmrich; Marc Steder; Dirk Koczan; Brigitte M Pützer
E2F1 in melanoma progression and metastasis.
Journal of the National Cancer Institute 2010;102(2):127-33.
2010: R F El-Kased; Cornelia Koy; Peter Lorenz; Susanne Drynda; Reinhard Guthke; Z Qian; Dirk Koczan; Y Li; Jörn Kekow; Hans-Jürgen Thiesen; Michael O Glocker
Mass spectrometric and peptide chip epitope analysis on the RA33 autoantigen with sera from rheumatoid arthritis patients.
European journal of mass spectrometry (Chichester, England) 2010;16(3):443-51.
2010: Peter Lorenz; Sabine Dietmann; Thomas Wilhelm; Dirk Koczan; Sandra Autran; Sophie Gad; Gaiping Wen; Guohui Ding; Yixue Li; Marie-Françoise Rousseau-Merck; Hans-Juergen Thiesen
The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues.
BMC genomics 2010;11():206.
2009: Ludwig G. Strauss; Johannes Hoffend; Dirk Koczan; Leyun Pan; Uwe Haberkorn; Antonia Dimitrakopoulou-Strauss
Early effects of FOLFOX treatment of colorectal tumour in an animal model: assessment of changes in gene expression and FDG kinetics.
European journal of nuclear medicine and molecular imaging 2009;36(8):1226-34.
2009: Dmitry Aminin; Conelia Koy; Pavel S Dmitrenok; Brigitte Müller-Hilke; Dirk Koczan; Brian Arbogast; Aleksandra A Silchenko; Vladimir I Kalinin; Sergey A Avilov; Valentin A Stonik; Peter D Collin; Hans-Juergen Thiesen; Max L Deinzer; Michael O Glocker
Immunomodulatory effects of holothurian triterpene glycosides on mammalian splenocytes determined by mass spectrometric proteome analysis.
Journal of proteomics 2009;72(5):886-906.
2009: Juliane Günther; Dirk Koczan; Wei Yang; Gerd Nürnberg; Dirk Repsilber; Hans-Joachim Schuberth; Zaneta Park; Nauman Maqbool; Adrian Molenaar; Hans-Martin Seyfert
Assessment of the immune capacity of mammary epithelial cells: comparison with mammary tissue after challenge with Escherichia coli.
Veterinary research 2009;40(4):31.
2009: D Engelmann; Dirk Koczan; P Ricken; U Rimpler; J Pahnke; Z Li; Brigitte M Pützer
Transcriptome analysis in mouse tumors induced by Ret-MEN2/FMTC mutations reveals subtype-specific role in survival and interference with immune surveillance.
Endocrine-related cancer 2009;16(1):211-24.
2009: Johannes Wollbold; René Huber; Dirk Pohlers; Dirk Koczan; Reinhard Guthke; Raimund W Kinne; Ulrike Gausmann
Adapted Boolean network models for extracellular matrix formation.
BMC systems biology 2009;3():77.
2009: Raphaël Riclet; Mariam Chendeb; Jean-Luc Vonesch; Dirk Koczan; Hans-Juergen Thiesen; Régine Losson; Florence Cammas
Disruption of the interaction between transcriptional intermediary factor 1{beta} and heterochromatin protein 1 leads to a switch from DNA hyper- to hypomethylation and H3K9 to H3K27 trimethylation on the MEST promoter correlating with gene reactivation.
Molecular biology of the cell 2009;20(1):296-305.
2008: Huu-Phuc Nguyen; Silke Metzger; Carsten Holzmann; Dirk Koczan; Hans-Jürgen Thiesen; Stephan von Hörsten; Olaf Riess; Michael Bonin
Age-dependent gene expression profile and protein expression in a transgenic rat model of Huntington's disease.
Proteomics. Clinical applications 2008;2(12):1638-50.
2008: Ludwig G. Strauss; Dirk Koczan; Sven Klippel; Leyun Pan; Caixia Cheng; Stefan Willis; Uwe Haberkorn; Antonia Dimitrakopoulou-Strauss
Impact of angiogenesis-related gene expression on the tracer kinetics of 18F-FDG in colorectal tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(8):1238-44.
2008: René Huber; Christian Hummert; Ulrike Gausmann; Dirk Pohlers; Dirk Koczan; Reinhard Guthke; Raimund W Kinne
Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane.
Arthritis research & therapy 2008;10(4):R98.
2008: Jens Vanselow; Gerd Nürnberg; Dirk Koczan; Martina Langhammer; Hans-Jürgen Thiesen; Norbert Reinsch
Expression profiling of a high-fertility mouse line by microarray analysis and qPCR.
BMC genomics 2008;9():307.
2008: Dirk Koczan; Susanne Drynda; Michael Hecker; Andreas Drynda; Reinhard Guthke; Jörn Kekow; Hans-Jürgen Thiesen
Molecular discrimination of responders and nonresponders to anti-TNF alpha therapy in rheumatoid arthritis by etanercept.
Arthritis research & therapy 2008;10(3):R50.
2008: Xinhua Yu; Dirk Koczan; Anna-Maija Sulonen; Denis A Akkad; Antje Kroner; Manuel Comabella; Gianna Costa; Daniela Corongiu; Robert Goertsches; Montserrat Camina-Tato; Hans-Jürgen Thiesen; Harald I Nyland; Sverre Mork; Xavier Montalban; Peter Rieckmann; Maria G Marrosu; Kjell-Morten Myhr; Joerg T Epplen; Janna Saarela; Saleh M Ibrahim
mtDNA nt13708A variant increases the risk of multiple sclerosis.
PloS one 2008;3(2):e1530.
2007: Ludwig G. Strauss; Leyun Pan; Dirk Koczan; Sven Klippel; Krzysztof Mikolajczyk; Cyrill Burger; Uwe Haberkorn; Klaus Schönleben; Hans-Jürgen Thiesen; Antonia Dimitrakopoulou-Strauss
Fusion of positron emission tomography (PET) and gene array data: a new approach for the correlative analysis of molecular biological and clinical data.
IEEE transactions on medical imaging 2007;26(6):804-12.
2007: Brit Fitzner; Peter Brock; Hana Nechutova; Anne Glass; Thomas Karopka; Dirk Koczan; Hans-Jürgen Thiesen; Gisela Sparmann; Jörg Emmrich; Stefan Liebe; Robert Jaster
Inhibitory effects of interferon-gamma on activation of rat pancreatic stellate cells are mediated by STAT1 and involve down-regulation of CTGF expression.
Cellular signalling 2007;19(4):782-90.
2007: Jochen Jaeger; Dirk Koczan; Hans-Jürgen Thiesen; Saleh M Ibrahim; Gerd Gross; Rainer Spang; Manfred Kunz
Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(3):806-15.
2007: Dirk Pohlers; Andreas Beyer; Dirk Koczan; Thomas Wilhelm; Hans-Jürgen Thiesen; Raimund W Kinne
Constitutive upregulation of the transforming growth factor-beta pathway in rheumatoid arthritis synovial fibroblasts.
Arthritis research & therapy 2007;9(3):R59.
2007: Soner Aksu; Dirk Koczan; Ulla Renne; Hans-Jürgen Thiesen; Gudrun A Brockmann
Differentially expressed genes in adipose tissues of high body weight-selected (obese) and unselected (lean) mouse lines.
Journal of applied genetics 2007;48(2):133-43.
2007: Xinhua Yu; Kristin Bauer; Dirk Koczan; Hans-Jürgen Thiesen; Saleh M Ibrahim
Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritis.
Arthritis research & therapy 2007;9(1):R3.
2007: Jeannette Henning; Dirk Koczan; Anne Glass; Thomas Karopka; Jens Pahnke; Arndt Rolfs; Reiner Benecke; Ulrike Gimsa
Deep brain stimulation in a rat model modulates TH, CaMKIIa and Homer1 gene expression.
The European journal of neuroscience 2007;25(1):239-50.
2006: Eilhard Mix; Saleh M Ibrahim; Jens Pahnke; Anne Glass; Ignacio Mazón-Peláez; Susanne Lemcke; Dirk Koczan; Ulrike Gimsa; Sven Bansemer; Thomas Scheel; Thomas Karopka; Tobias Böttcher; Jana Müller; Eike Dazert; Veronica Antipova; Raimund Hoffrogge; Andreas Wree; Marlies Zschiesche; Ulf Strauss; Günther Kundt; Rolf Warzok; Lothar Gierl; Arndt Rolfs
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor Atorvastatin mediated effects depend on the activation status of target cells in PLP-EAE.
Journal of autoimmunity 2006;27(4):251-65.
2006: Xinhua Yu; Kristin Bauer; Patrik Wernhoff; Dirk Koczan; Steffen Möller; Hans-Jürgen Thiesen; Saleh M Ibrahim
Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7042-9.
2006: Pierre Kunz; Johannes Hoffend; Annette Altmann; Antonia Dimitrakopoulou-Strauss; Dirk Koczan; Michael Eisenhut; Gabriel A Bonaterra; Thomas J Dengler; Walter Mier; Uwe Haberkorn; Ralf Kinscherf
Angiopoietin-2 overexpression in morris hepatoma results in increased tumor perfusion and induction of critical angiogenesis-promoting genes.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(9):1515-24.
2006: Kerstin Schmidt; Johannes Hoffend; Annette Altmann; Fabian Kiessling; Ludwig G. Strauss; Dirk Koczan; Walter Mier; Michael Eisenhut; Ralf Kinscherf; Uwe Haberkorn
Troponin I overexpression inhibits tumor growth, perfusion, and vascularization of morris hepatoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(9):1506-14.
2006: Dirk Koczan; Hans-Jürgen Thiesen
Survey of microarray technologies suitable to elucidate transcriptional networks as exemplified by studying KRAB zinc finger gene families.
Proteomics 2006;6(17):4704-15.
2006: Oliver Drognitz; Philip Michel; Dirk Koczan; Hannes Neeff; Yukio Mikami; Robert Obermaier; Hans-Jürgen Thiesen; Ulrich T Hopt; Marian Loebler
Characterization of ischemia/reperfusion-induced gene expression in experimental pancreas transplantation.
Transplantation 2006;81(10):1428-34.
2006: Sandra Mahr; Gerd R Burmester; Dietmar Hilke; Udo Göbel; Andreas Grützkau; Thomas Häupl; Matthias Hauschild; Dirk Koczan; Veit Krenn; Jasper Neidel; Carsten Perka; Andreas Radbruch; Hans-Jürgen Thiesen; Brigitte Müller
Cis- and trans-acting gene regulation is associated with osteoarthritis.
American journal of human genetics 2006;78(5):793-803.
2006: Andrea Jochheim-Richter; Urda Rüdrich; Dirk Koczan; Tina Hillemann; Simon Tewes; Marianne Petry; Andreas Kispert; Amar Deep Sharma; Farrah Attaran; Michael P Manns; Michael Ott
Gene expression analysis identifies novel genes participating in early murine liver development and adult liver regeneration.
Differentiation; research in biological diversity 2006;74(4):167-73.
2006: Kerstin Schmidt; Johannes Hoffend; Annette Altmann; Ludwig G. Strauss; Antonia Dimitrakopoulou-Strauss; Britta Engelhardt; Dirk Koczan; Jörg Peter; Thomas J Dengler; Walter Mier; Michael Eisenhut; Uwe Haberkorn; Ralf Kinscherf
Angiostatin overexpression in Morris hepatoma results in decreased tumor growth but increased perfusion and vascularization.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(3):543-51.
2006: Robert Goertsches; Pablo Serrano-Fernández; Steffen Möller; Dirk Koczan; Uwe K Zettl
Multiple sclerosis therapy monitoring based on gene expression.
Current pharmaceutical design 2006;12(29):3761-79.
2006: Martin Hoffmann; Dirk Pohlers; Dirk Koczan; Hans-Jürgen Thiesen; Stefan Wölfl; Raimund W Kinne
Robust computational reconstitution - a new method for the comparative analysis of gene expression in tissues and isolated cell fractions.
BMC bioinformatics 2006;7():369.
2005: Gisela Sparmann; Anne Glass; Peter Brock; Robert Jaster; Dirk Koczan; Hans-Jürgen Thiesen; Stefan Liebe; Jörg Emmrich
Inhibition of lymphocyte apoptosis by pancreatic stellate cells: impact of interleukin-15.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(5):G842-51.
2005: Harald H Hofstetter; Saleh M Ibrahim; Dirk Koczan; Niels Kruse; Andreas Weishaupt; Klaus V Toyka; Ralf Gold
Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis.
Cellular immunology 2005;237(2):123-30.
2005: Vassilis Aidinis; piero carninci; Maria Armaka; Walter Witke; Vaggelis Harokopos; Norman Pavelka; Dirk Koczan; Christos Argyropoulos; Maung-Maung Thwin; Steffen Möller; Kazunori Waki; Waki Kazunori; Ponnampalam Gopalakrishnakone; Paola Ricciardi-Castagnoli; Hans-Jürgen Thiesen; Yoshihide Hayashizaki; george kollias
Cytoskeletal rearrangements in synovial fibroblasts as a novel pathophysiological determinant of modeled rheumatoid arthritis.
PLoS genetics 2005;1(4):e48.
2005: Susanne Vogler; René Goedde; Bianca Miterski; Ralf Gold; Antje Kroner; Dirk Koczan; Uwe K Zettl; Peter Rieckmann; Jörg T Epplen; Saleh M Ibrahim
Association of a common polymorphism in the promoter of UCP2 with susceptibility to multiple sclerosis.
Journal of molecular medicine (Berlin, Germany) 2005;83(10):806-11.
2005: M Johannesson; L M Olsson; Anna-Karin B Lindqvist; S Möller; Dirk Koczan; L Wester-Rosenlöf; H-J Thiesen; S Ibrahim; Rikard Holmdahl
Gene expression profiling of arthritis using a QTL chip reveals a complex gene regulation of the Cia5 region in mice.
Genes and immunity 2005;6(7):575-83.
2005: Michael Klenk; Dirk Koczan; Reinhard Guthke; Masanobu Nakata; Hans-Jürgen Thiesen; Andreas Podbielski; Bernd Kreikemeyer
Global epithelial cell transcriptional responses reveal Streptococcus pyogenes Fas regulator activity association with bacterial aggressiveness.
Cellular microbiology 2005;7(9):1237-50.
2005: Robert Jaster; Philipp Lichte; Brit Fitzner; Peter Brock; Anne Glass; Thomas Karopka; Lothar Gierl; Dirk Koczan; Hans-Jürgen Thiesen; Gisela Sparmann; Jörg Emmrich; Stefan Liebe
Peroxisome proliferator-activated receptor gamma overexpression inhibits pro-fibrogenic activities of immortalised rat pancreatic stellate cells.
Journal of cellular and molecular medicine 2005;9(3):670-82.
2005: Dirk Koczan; Reinhard Guthke; Hans-Jürgen Thiesen; Saleh M Ibrahim; Günther Kundt; Helga Krentz; Gerd Gross; Manfred Kunz
Gene expression profiling of peripheral blood mononuclear leukocytes from psoriasis patients identifies new immune regulatory molecules.
European journal of dermatology : EJD 2005;15(4):251-7.
2005: Anne Glass; Jeannette Henning; Thomas Karopka; Thomas Scheel; Sven Bansemer; Dirk Koczan; Lothar Gierl; Arndt Rolfs; Ulrike Gimsa
Representation of individual gene expression in completely pooled mRNA samples.
Bioscience, biotechnology, and biochemistry 2005;69(6):1098-103.
2005: Pablo Serrano-Fernández; Saleh M Ibrahim; Dirk Koczan; Uwe K Zettl; Steffen Möller
In silico fine-mapping: narrowing disease-associated loci by intergenomics.
Bioinformatics (Oxford, England) 2005;21(8):1737-8.
2005: Robert Obermaier; P Michel; Ernst von Dobschuetz; Marian Löbler; HJ Thiessen; Dirk Koczan; Ulrich T Hopt; Stefan Benz
Protective effect of endotoxin preconditioning in pancreas: analysis with DNA chip arrays.
Transplantation proceedings 2005;37(3):1632-4.
2005: Kerstin Schmidt; Johannes Hoffend; Annette Altmann; Ludwig G. Strauss; Antonia Dimitrakopoulou-Strauss; Britta Engelhardt; Dirk Koczan; Jörg Peter; Silke Vorwald; Helmut Eskerski; Michael Eisenhut; Jürgen Metz; Ralf Kinscherf; Uwe Haberkorn
Transfer of the sFLT-1 gene in Morris hepatoma results in decreased growth and perfusion and induction of genes associated with stress response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(6):2132-40.
2005: Kristin Bauer; Annika Knipper; Dirk Koczan; Hans Jürgen Kreutzer; Horst Nizze; Eilhard Mix; Hans-Jürgen Thiesen; Rikard Holmdahl; Hoang Tu-Rapp; Saleh M Ibrahim
Perforin deficiency attenuates collagen-induced arthritis.
Arthritis research & therapy 2005;7(4):R877-84.
2005: Philip Gierer; Saleh Ibrahim; Thomas Mittlmeier; Dirk Koczan; Steffen Moeller; Jürgen Landes; Georg Gradl; Brigitte Vollmar
Gene expression profile and synovial microcirculation at early stages of collagen-induced arthritis.
Arthritis research & therapy 2005;7(4):R868-76.
2005: Steffen Möller; Eilhard Mix; Martin Blüggel; Pablo Serrano-Fernández; Dirk Koczan; Vasilis Kotsikoris; Manfred Kunz; Michael Watson; Jens Pahnke; Harald Illges; Michael Kreutzer; Stefan Mikkat; Hans-Jürgen Thiesen; Michael O Glocker; Uwe K Zettl; Saleh M Ibrahim
Collection of soluble variants of membrane proteins for transcriptomics and proteomics.
In silico biology 2005;5(3):295-311.
2004: Kristin Bauer; Xinhua Yu; Patrik Wernhoff; Dirk Koczan; Hans-Jürgen Thiesen; Saleh M Ibrahim
Identification of new quantitative trait loci in mice with collagen-induced arthritis.
Arthritis and rheumatism 2004;50(11):3721-8.
2004: Frank Pfeffer; Dirk Koczan; Ulrich Adam; Stefan Benz; Ernst von Dobschuetz; Friedrich Prall; Horst Nizze; Hans-Jürgen Thiesen; Ulrich T Hopt; Marian Löbler
Expression of connexin26 in islets of Langerhans is associated with impaired glucose tolerance in patients with pancreatic adenocarcinoma.
Pancreas 2004;29(4):284-90.
2004: M Kunz; Saleh M Ibrahim; Dirk Koczan; S Scheid; Hans-Jürgen Thiesen; G Gross
DNA microarray technology and its applications in dermatology.
Experimental dermatology 2004;13(10):593-606.
2004: Ludwig G. Strauss; Antonia Dimitrakopoulou-Strauss; Dirk Koczan; Ludger Bernd; Uwe Haberkorn; Volker Ewerbeck; Hans-Jürgen Thiesen
18F-FDG kinetics and gene expression in giant cell tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(9):1528-35.
2004: Jens Pahnke; Eilhard Mix; Rupert Knoblich; Jana Müller; Marlies Zschiesche; Beke Schubert; Dirk Koczan; Peter Bauer; Tobias Böttcher; Hans-Jürgen Thiesen; Ludmil Lazarov; Andreas Wree; Arndt Rolfs
Overexpression of glial cell line-derived neurotrophic factor induces genes regulating migration and differentiation of neuronal progenitor cells.
Experimental cell research 2004;297(2):484-94.
2004: Gisela Sparmann; Christine Hohenadl; Jens Tornøe; Robert Jaster; Brit Fitzner; Dirk Koczan; Hans-Jürgen Thiesen; Anne Glass; David Winder; Stefan Liebe; Jörg Emmrich
Generation and characterization of immortalized rat pancreatic stellate cells.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(1):G211-9.
2004: Eilhard Mix; Saleh Ibrahim; Jens Pahnke; Dirk Koczan; Christian Sina; Tobias Böttcher; Hans-Jürgen Thiesen; Arndt Rolfs
Gene-expression profiling of the early stages of MOG-induced EAE proves EAE-resistance as an active process.
Journal of neuroimmunology 2004;151(1-2):158-70.
2004: Oliver Stachs; A Bochert; T Gerber; Dirk Koczan; HJ Thiessen; Rudolf F Guthoff
[The extracellular matrix structure in keratoconus].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2004;101(4):384-9.
2004: Jürgen E Bader; Cornelia M Deckert; Norman Koglin; Franka Pluder; Karin Mörl; Dirk Koczan; Hans-Jürgen Thiesen; Annette G Beck-Sickinger
From transcription profile to expression: the signaling repertoire of the SK-N-MC neuroepithelioma cell-line.
Journal of receptor and signal transduction research 2004;24(4):257-82.
2004: Steffen Möller; Dirk Koczan; Pablo Serrano-Fernandez; Uwe K Zettl; Hans-Jürgen Thiesen; Saleh M Ibrahim
Selecting SNPs for association studies based on population frequencies: a novel interactive tool and its application to polygenic diseases.
In silico biology 2004;4(4):417-27.
2004: Katja Brocke-Heidrich; Antje K Kretzschmar; Gabriele Pfeifer; Christian Henze; Dennis Löffler; Dirk Koczan; Hans-Jürgen Thiesen; Renate Burger; Martin Gramatzki; Friedemann Horn
Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation.
Blood 2004;103(1):242-51.
2003: Manfred Kunz; Steffen Moeller; Dirk Koczan; Peter Lorenz; Roland H Wenger; Michael O Glocker; Hans-Jürgen Thiesen; Gerd Gross; Saleh M Ibrahim
Mechanisms of hypoxic gene regulation of angiogenesis factor Cyr61 in melanoma cells.
The Journal of biological chemistry 2003;278(46):45651-60.
2003: A Bochert; Jens Berlau; Dirk Koczan; B Seitz; HJ Thiessen; Rudolf Guthoff
[Gene expression in keratoconus. Initial results using DNA microarrays].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2003;100(7):545-9.
2003: Tobias Böttcher; Eilhard Mix; Dirk Koczan; Peter Bauer; Jens Pahnke; Sabine Peters; Sabine Weinelt; Rupert Knoblich; Ulf Strauss; Elena Cattaneo; Hans-Jürgen Thiesen; Arndt Rolfs
Gene expression profiling of ciliary neurotrophic factor-overexpressing rat striatal progenitor cells (ST14A) indicates improved stress response during the early stage of differentiation.
Journal of neuroscience research 2003;73(1):42-53.
2003: Peter Lorenz; Peter Ruschpler; Dirk Koczan; Peter Stiehl; Hans-Jürgen Thiesen
From transcriptome to proteome: differentially expressed proteins identified in synovial tissue of patients suffering from rheumatoid arthritis and osteoarthritis by an initial screen with a panel of 791 antibodies.
Proteomics 2003;3(6):991-1002.
2003: Jane Guy; Tom Hearn; Moira Crosier; Jonathan M Mudge; Luigi Viggiano; Dirk Koczan; Hans-Jurgen Thiesen; Jeffrey A Bailey; Julie E Horvath; Evan E Eichler; Mark E Earthrowl; Panos Deloukas; Lisa French; Jane Rogers; David Bentley; Michael S Jackson
Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p.
Genome research 2003;13(2):159-72.
2003: Lena Wester; Dirk Koczan; Jens Holmberg; Peter Olofsson; Hans-Jürgen Thiesen; Rikard Holmdahl; Saleh Ibrahim
Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats.
Arthritis research & therapy 2003;5(6):R361-72.
2003: Peter Ruschpler; Peter Lorenz; Wolfram Eichler; Dirk Koczan; Claudia Hänel; Roger Scholz; Christian Melzer; Hans-Jürgen Thiesen; Peter Stiehl
High CXCR3 expression in synovial mast cells associated with CXCL9 and CXCL10 expression in inflammatory synovial tissues of patients with rheumatoid arthritis.
Arthritis research & therapy 2003;5(5):R241-52.
2003: Vassilis Aidinis; David Plows; Sylva Haralambous; Maria Armaka; Petros Papadopoulos; Maria Zambia Kanaki; Dirk Koczan; Hans Juergen Thiesen; george kollias
Functional analysis of an arthritogenic synovial fibroblast.
Arthritis research & therapy 2003;5(3):R140-57.
2002: Stefan Benz; Marian Löbler; Robert Obermaier; Berith Kortmann; Frank Pfeffer; Dirk Koczan; Hans-Jürgen Thiesen; Ulrich T Hopt
New possible target genes in pancreatic ischemia/reperfusion-injury identified by microarray analysis.
Transplantation proceedings 2002;34(6):2369-71.
2002: Toralf Reimer; Dirk Koczan; B Gerber; D Richter; Hans-Jürgen Thiesen; Klaus Friese
Microarray analysis of differentially expressed genes in placental tissue of pre-eclampsia: up-regulation of obesity-related genes.
Molecular human reproduction 2002;8(7):674-80.
2002: Saleh M Ibrahim; Dirk Koczan; Hans-Jürgen Thiesen
Gene-expression profile of collagen-induced arthritis.
Journal of autoimmunity 2002;18(2):159-67.
2002: M Kunz; Dirk Koczan; Saleh M Ibrahim; R Gillitzer; G Gross; Hans-Jürgen Thiesen
Differential expression of thrombospondin 2 in primary and metastatic malignant melanoma.
Acta dermato-venereologica 2002;82(3):163-9.
2002: Toralf Reimer; Dirk Koczan; Heiner Müller; Klaus Friese; Hans-Jürgen Thiesen; Bernd Gerber
Tumour Fas ligand:Fas ratio greater than 1 is an independent marker of relative resistance to tamoxifen therapy in hormone receptor positive breast cancer.
Breast cancer research : BCR 2002;4(5):R9.
2001: Saleh M Ibrahim; Eilhard Mix; Tobias Böttcher; Dirk Koczan; Ralf Gold; Arndt Rolfs; Hans-Jürgen Thiesen
Gene expression profiling of the nervous system in murine experimental autoimmune encephalomyelitis.
Brain : a journal of neurology 2001;124(Pt 10):1927-38.
2001: Saleh M Ibrahim; Jörg Ringel; C Schmidt; Bruno Ringel; P Müller; Dirk Koczan; Hans-Jürgen Thiesen; Matthias Löhr
Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death.
Pancreas 2001;23(1):72-9.
2001: Peter Lorenz; Dirk Koczan; Hans-Jürgen Thiesen
Transcriptional repression mediated by the KRAB domain of the human C2H2 zinc finger protein Kox1/ZNF10 does not require histone deacetylation.
Biological chemistry 2001;382(4):637-44.
2000: Toralf Reimer; C Herrnring; Dirk Koczan; D Richter; Bernd Gerber; D Kabelitz; Klaus Friese; Hans-Jürgen Thiesen
FasL:Fas ratio--a prognostic factor in breast carcinomas.
Cancer research 2000;60(4):822-8.
2000: Toralf Reimer; Dirk Koczan; Heiner Müller; Klaus Friese; A Krause; Hans-Jürgen Thiesen; Bernd Gerber
Human chorionic gonadotrophin-beta transcripts correlate with progesterone receptor values in breast carcinomas.
Journal of molecular endocrinology 2000;24(1):33-41.
2000: Toralf Reimer; Dirk Koczan; Volker Briese; Klaus Friese; D Richter; Hans-Jürgen Thiesen; Udo Jeschke
Absolute quantification of human chorionic gonadotropin-beta mRNA with TaqMan detection. 4.
Molecular biotechnology 2000;14(1):47-57.
1999: Bruno Ringel; Saleh M Ibrahim; H Köhler; Jörg Ringel; Dirk Koczan; Stefan Liebe; Matthias Löhr; Hans-Jürgen Thiesen
Apoptotic molecules in pancreatic carcinoma cell lines.
Annals of the New York Academy of Sciences 1999;880():175-8.
1998: F L Lim; M Soulez; Dirk Koczan; Hans-Jürgen Thiesen; J C Knight
A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas.
Oncogene 1998;17(15):2013-8.
1997: Hans-Jürgen Thiesen; Dirk Koczan; Saleh M Ibrahim
The role of apoptosis in autoimmune disease with special reference to juvenile chronic arthritis.
Revue du rhumatisme (English ed.) 1997;64(10 Suppl):140S-143S.