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Tatsuhiko Kodama

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Toru Suzuki; Junko Tsuzuku; Takao Hamakubo; Akiyo Hayashi; Hiroko Iwanari; Tatsuhiko Kodama; Hisao Masai; Yasuhiro Mochizuki; Hideo Nishitani; Yasushi Shiomi; Tadashi Yamamoto
Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob.
Osamu Kusano-Arai; Yasuhiro Mochizuki; Hiromi Nakata; Hiroko Iwanari; Toshiyuki Kitoh; Tatsuhiko Kodama; Takao Hamakubo
Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies.
Yoshihiro Ohta; Yijun Ruan; Tetsuji Tokihiro; Takashi Tsuboi; Yoichiro Wada; Tatsuhiko Kodama; Akinobu Nishiyama; Sigeo Ihara
Path-preference cellular-automaton model for traffic flow through transit points and its application to the transcription process in human cells.

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2012: Toru Suzuki; Junko Tsuzuku; Takao Hamakubo; Akiyo Hayashi; Hiroko Iwanari; Tatsuhiko Kodama; Hisao Masai; Yasuhiro Mochizuki; Hideo Nishitani; Yasushi Shiomi; Tadashi Yamamoto
Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob.
The Journal of biological chemistry 2012;287(48):40256-65.
2012: Osamu Kusano-Arai; Yasuhiro Mochizuki; Hiromi Nakata; Hiroko Iwanari; Toshiyuki Kitoh; Tatsuhiko Kodama; Takao Hamakubo
Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies.
Hybridoma (2005) 2012;31(5):325-32.
2012: Yoshihiro Ohta; Yijun Ruan; Tetsuji Tokihiro; Takashi Tsuboi; Yoichiro Wada; Tatsuhiko Kodama; Akinobu Nishiyama; Sigeo Ihara
Path-preference cellular-automaton model for traffic flow through transit points and its application to the transcription process in human cells.
Physical review. E, Statistical, nonlinear, and soft matter physics 2012;86(2 Pt 1):021918.
2012: Shota Kudo; Tadashi Matsuura; Takamitsu Miyafusa; Yukio Sudou; Jose M M Caaveiro; Shuichiro Goda; Takao Hamakubo; Keisuke Ishii; Tatsuhiko Kodama; Kouhei Tsumoto
Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin.
Molecular bioSystems 2012;8(8):2050-3.
2012: Mikihito Hayashi; Tatsuhiko Kodama; Atsushi Kumanogoh; Tomoki Nakashima; Masahiko Taniguchi; Hiroshi Takayanagi
Osteoprotection by semaphorin 3A.
Nature 2012;485(7396):69-74.
2012: Koji Fujita; Toru Fukuda; Hiroshi Itoh; Makiko Iwasaki; Shigeaki Kato; Tatsuhiko Kodama; Chengshan Ma; Takeshi Miyamoto; Takako Negishi-Koga; Hiroki Ochi; Atsushi Okawa; Kenichi Shinomiya; Satoko Sunamura; Hiroshi Takayanagi; Kimitaka Takitani; Hiroshi Tamai; Hiroyuki Arai; Shu Takeda
Vitamin E decreases bone mass by stimulating osteoclast fusion.
Nature medicine 2012;18(4):589-94.
2012: Ikuo Hayashi; Hiroko Iwanari; S Chiba; Takao Hamakubo; Tatsuhiko Kodama; Tong Li; Y Miyake; Yuichi Morohashi; S Osawa; Mamiko Sakata-Yanagimoto; J Takagi; S Takatori; Taisuke Tomita; Yasuomi Urano; Philip C Wong; Takeshi Iwatsubo
Neutralization of the γ-secretase activity by monoclonal antibody against extracellular domain of nicastrin.
Oncogene 2012;31(6):787-98.
2011: Yoshihiro Ohta; Tatsuhiko Kodama; Sigeo Ihara
Cellular-automaton model of the cooperative dynamics of RNA polymerase II during transcription in human cells.
Physical review. E, Statistical, nonlinear, and soft matter physics 2011;84(4 Pt 1):041922.
2011: Hironori Waki; Toshimasa Yamauchi; Jing Yu; Hiroyuki Aburatani; Tomohisa Aoyama; Takanori Fujita; Lisa Hirose-Yotsuya; Masato Iwabu; Tatsuhiko Kodama; Masahiro Nakamura; Miki Okada-Iwabu; Juro Sakai; Wei Sun; Kazumi Take; Shuichi Tsutsumi; Kohjiro Ueki; Ken-ichi Wakabayashi; Takashi Kadowaki
Global mapping of cell type-specific open chromatin by FAIRE-seq reveals the regulatory role of the NFI family in adipocyte differentiation.
PLoS genetics 2011;7(10):e1002311.
2011: Tomoki Nakashima; Masatsugu Oh-hora; Josef M Penninger; Lynda F Bonewald; Jian Q Feng; Takanobu Fukunaga; Mikihito Hayashi; Tatsuhiko Kodama; Kosaku Kurata; Erwin F Wagner; Anton Wutz; Hiroshi Takayanagi
Evidence for osteocyte regulation of bone homeostasis through RANKL expression.
Nature medicine 2011;17(10):1231-4.
2011: Erik Idrus; Tatsuhiko Kodama; Tomoki Nakashima; Kazuo Okamoto; Nobuyuki Tanaka; Tadatsugu Taniguchi; Ling Wang; Mikihito Hayashi; Hiroshi Takayanagi
The role of the BH3-only protein Noxa in bone homeostasis.
Biochemical and biophysical research communications 2011;410(3):620-5.
2011: Yasuharu Kanki; Tatsuhiko Kodama; Takahide Kohro; Imari Mimura; Hiroyuki Aburatani; Takao Hamakubo; Sigeo Ihara; Hiroko Iwanari; Shuying Jiang; Makoto Naito; Yoshihiro Ohta; Jun-Ichi Suehiro; Shuichi Tsutsumi; Youichiro Wada; Takashi Minami
Epigenetically coordinated GATA2 binding is necessary for endothelium-specific endomucin expression.
The EMBO journal 2011;30(13):2582-95.
2011: Hiroko Iwanari; Tatsuhiko Kodama; Osamu Kusano-Arai; Yoshiko Nakada-Nakura; Toshiko Sakihama; Nobuchika Suzuki; Takao Hamakubo
A method of generating antibodies against exogenously administered self-antigen by manipulating CD4+CD25+ regulatory T cells.
Journal of immunological methods 2011;369(1-2):108-14.
2011: Hideto Tozawa; Yasuharu Kanki; Jun-ichi Suehiro; Shuichi Tsutsumi; Takahide Kohro; Youichiro Wada; Hiroyuki Aburatani; William C Aird; Tatsuhiko Kodama; Takashi Minami
Genome-wide approaches reveal functional interleukin-4-inducible STAT6 binding to the vascular cell adhesion molecule 1 promoter.
Molecular and cellular biology 2011;31(11):2196-209.
2011: Alexander S Savchenko; Akira Inoue; Riuko Ohashi; Shuying Jiang; Go Hasegawa; Toshiya Tanaka; Takao Hamakubo; Tatsuhiko Kodama; Yutaka Aoyagi; Tatsuo Ushiki; Makoto Naito
Long pentraxin 3 (PTX3) expression and release by neutrophils in vitro and in ulcerative colitis.
Pathology international 2011;61(5):290-7.
2011: Ryosuke Kunii; Shuying Jiang; Go Hasegawa; Takashi Yamamoto; Hajime Umezu; Takehiro Watanabe; Masanori Tsuchida; Takehisa Hashimoto; Takao Hamakubo; Tatsuhiko Kodama; Keisuke Sasai; Makoto Naito
The predominant expression of hepatocyte nuclear factor 4α (HNF4α) in thyroid transcription factor-1 (TTF-1)-negative pulmonary adenocarcinoma.
Histopathology 2011;58(3):467-76.
2011: Kenji Daigo; Takeshi Kawamura; Y Ohta; Riuko Ohashi; Satoshi Katayose; Toshiya Tanaka; Hiroyuki Aburatani; Makoto Naito; Tatsuhiko Kodama; Sigeo Ihara; Takao Hamakubo
Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.
The Journal of biological chemistry 2011;286(1):674-86.
2011: Takako Negishi-Koga; Masahiro Shinohara; Haruhiko Bito; Roland H Friedel; Tatsuhiko Kodama; Noriko Komatsu; Hiroshi Takayanagi
Suppression of bone formation by osteoclastic expression of semaphorin 4D.
Nature medicine 2011;17(11):1473-80.
2011: Imari Mimura; Tetsuhiro Tanaka; Youichiro Wada; Tatsuhiko Kodama; Masaomi Nangaku
Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: epigenetic regulation of the hypoxic response via hypoxia-inducible factor and histone modifying enzymes.
Journal of pharmacological sciences 2011;115(4):453-8.
2010: Yoko Ogawa Akazawa; Yoshiro Saito; Takao Hamakubo; Yoshinori Masuo; Yasukazu Yoshida; Keiko Nishio; Mototada Shichiri; Tomohiro Miyasaka; Hiroko Iwanari; Yasuhiro Mochizuki; Tatsuhiko Kodama; Noriko Noguchi; Etsuo Niki
Elevation of oxidized DJ-1 in the brain and erythrocytes of Parkinson disease model animals.
Neuroscience letters 2010;483(3):201-5.
2010: Motoaki Seki; Akira Watanabe; Satoshi Enomoto; Takeshi Kawamura; Hirotaka Ito; Tatsuhiko Kodama; Takao Hamakubo; Hiroyuki Aburatani
Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells.
FEBS letters 2010;584(13):2909-15.
2010: Hiroshi Kanamori; Kazuhito Yuhashi; Shin Ohnishi; Kazuhiko Koike; Tatsuhiko Kodama
RNA-dependent RNA polymerase of hepatitis C virus binds to its coding region RNA stem-loop structure, 5BSL3.2, and its negative strand.
The Journal of general virology 2010;91(Pt 5):1207-12.
2010: Jun-ichi Suehiro; Takao Hamakubo; Tatsuhiko Kodama; William C Aird; Takashi Minami
Vascular endothelial growth factor activation of endothelial cells is mediated by early growth response-3.
Blood 2010;115(12):2520-32.
2010: Mikihito Hayashi; Tomoki Nakashima; Tatsuhiko Kodama; Andrew P Makrigiannis; Noriko Toyama-Sorimachi; Hiroshi Takayanagi
Ly49Q, an ITIM-bearing NK receptor, positively regulates osteoclast differentiation.
Biochemical and biophysical research communications 2010;393(3):432-8.
2010: Keizo Nishikawa; Tomoki Nakashima; Mikihito Hayashi; Takanobu Fukunaga; Shigeaki Kato; Tatsuhiko Kodama; Satoru Takahashi; Kathryn Calame; Hiroshi Takayanagi
Blimp1-mediated repression of negative regulators is required for osteoclast differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(7):3117-22.
2010: M Inoue; Atsumi Iida; Shinya Satoh; Tatsuhiko Kodama; Sumiko Watanabe
COUP-TFI and -TFII nuclear receptors are expressed in amacrine cells and play roles in regulating the differentiation of retinal progenitor cells.
Experimental eye research 2010;90(1):49-56.
2009: Hideyuki Yanai; Tatsuma Ban; ZhiChao Wang; Myoung Kwon Choi; Takeshi Kawamura; Hideo Negishi; Makoto Nakasato; Yan Lu; Sho Hangai; Ryuji Koshiba; David Savitsky; Lorenza Ronfani; Shizuo Akira; Marco E Bianchi; Kenya Honda; Tomohiko Tamura; Tatsuhiko Kodama; Tadatsugu Taniguchi
HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.
Nature 2009;462(7269):99-103.
2009: Youichiro Wada; Yoshihiro Ohta; Meng Xu; Shuichi Tsutsumi; Takashi Minami; Kenji Inoue; Daisuke Komura; Jun'ichi Kitakami; Nobuhiko Oshida; Argyris Papantonis; Akashi Izumi; Mika Kobayashi; Hiroko Meguro; Yasuharu Kanki; Imari Mimura; Kazuki Yamamoto; Chikage Mataki; Takao Hamakubo; Katsuhiko Shirahige; Hiroyuki Aburatani; Hiroshi Kimura; Tatsuhiko Kodama; Peter R Cook; Sayoko Ihara
A wave of nascent transcription on activated human genes.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18357-61.
2009: Haihua Song; Jun-ichi Suehiro; Yasuharu Kanki; Yoshiko Kawai; Kenji Inoue; Hiroyuki Daida; Kiichiro Yano; Toshio Ohhashi; Peter Oettgen; William C Aird; Tatsuhiko Kodama; Takashi Minami
Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.
The Journal of biological chemistry 2009;284(42):29109-24.
2009: Ikuo Hayashi; Sho Takatori; Yasuomi Urano; Hiroko Iwanari; Noriko Isoo; Satoko Osawa; Maiko A Fukuda; Tatsuhiko Kodama; Takao Hamakubo; Tong Li; Philip C Wong; Taisuke Tomita; Takeshi Iwatsubo
Single chain variable fragment against nicastrin inhibits the gamma-secretase activity.
The Journal of biological chemistry 2009;284(41):27838-47.
2009: Shinya Satoh; Ke Tang; Atsumi Iida; M Inoue; Tatsuhiko Kodama; Sophia Y Tsai; Ming-Jer Tsai; Yasuhide Furuta; Sumiko Watanabe
The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(40):12401-11.
2009: Takeshi Inagaki; Makoto Tachibana; Kenta Magoori; Hiromi Kudo; Toshiya Tanaka; Masashi Okamura; Makoto Naito; Tatsuhiko Kodama; Yoichi Shinkai; Juro Sakai
Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice.
Genes to cells : devoted to molecular & cellular mechanisms 2009;14(8):991-1001.
2009: Takashi Minami; Kiichiro Yano; Mai Miura; Mika Kobayashi; Jun-ichi Suehiro; Patrick C Reid; Takao Hamakubo; Sandra Ryeom; William C Aird; Tatsuhiko Kodama
The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.
The Journal of clinical investigation 2009;119(8):2257-70.
2009: Kabuto Takano; Go Hasegawa; Shuying Jiang; Isao Kurosaki; Katsuyoshi Hatakeyama; Hiroko Iwanari; Toshiya Tanaka; Takao Hamakubo; Tatsuhiko Kodama; Makoto Naito
Immunohistochemical staining for P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha may complement mucin phenotype of differentiated-type early gastric carcinoma.
Pathology international 2009;59(7):462-70.
2009: Ken-ichi Wakabayashi; Masashi Okamura; Shuichi Tsutsumi; Naoko S Nishikawa; Toshiya Tanaka; Iori Sakakibara; Jun-ichi Kitakami; Sigeo Ihara; Yuichi Hashimoto; Takao Hamakubo; Tatsuhiko Kodama; Hiroyuki Aburatani; Juro Sakai
The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop.
Molecular and cellular biology 2009;29(13):3544-55.
2009: Daichi Maeda; Satoshi Ota; Yutaka Takazawa; Hiroyuki Aburatani; Shunsuke Nakagawa; Tetsu Yano; Yuji Taketani; Tatsuhiko Kodama; Masashi Fukayama
Glypican-3 expression in clear cell adenocarcinoma of the ovary.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009;22(6):824-32.
2009: Hiroshi Kanamori; Kazuhito Yuhashi; Yasutoshi Uchiyama; Tatsuhiko Kodama; Shin Ohnishi
In vitro selection of RNA aptamers that bind the RNA-dependent RNA polymerase of hepatitis C virus: a possible role of GC-rich RNA motifs in NS5B binding.
Virology 2009;388(1):91-102.
2009: Masashi Okamura; Hiromi Kudo; Ken-ichi Wakabayashi; Toshiya Tanaka; Aya Nonaka; Aoi Uchida; Shuichi Tsutsumi; Iori Sakakibara; Makoto Naito; Timothy F Osborne; Takao Hamakubo; Sadayoshi Ito; Hiroyuki Aburatani; Masashi Yanagisawa; Tatsuhiko Kodama; Juro Sakai
COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(14):5819-24.
2009: Tetsuo Ushiku; Hiroshi Uozaki; Aya Shinozaki; Satoshi Ota; Keisuke Matsuzaka; Sachiyo Nomura; Michio Kaminishi; Hiroyuki Aburatani; Tatsuhiko Kodama; Masashi Fukayama
Glypican 3-expressing gastric carcinoma: distinct subgroup unifying hepatoid, clear-cell, and alpha-fetoprotein-producing gastric carcinomas.
Cancer science 2009;100(4):626-32.
2009: Toshihiro Kazawa; Takashi Kawasaki; Azusa Sakamoto; Masaru Imamura; Riuko Ohashi; Shuying Jiang; Toshiya Tanaka; Hiroko Iwanari; Takao Hamakubo; Juro Sakai; Tatsuhiko Kodama; Makoto Naito
Expression of liver X receptor alpha and lipid metabolism in granulocyte-macrophage colony-stimulating factor-induced human monocyte-derived macrophage.
Pathology international 2009;59(3):152-60.
2009: Nobuchika Suzuki; Kouhei Tsumoto; Nicole Hajicek; Kenji Daigo; Reiko Tokita; Shiro Minami; Tatsuhiko Kodama; Takao Hamakubo; Tohru Kozasa
Activation of leukemia-associated RhoGEF by Galpha13 with significant conformational rearrangements in the interface.
The Journal of biological chemistry 2009;284(8):5000-9.
2009: Yuriko Minegishi; Hiroko Iwanari; Yasuhiro Mochizuki; Takako Horii; Tomoko Hoshino; Tatsuhiko Kodama; Takao Hamakubo; Noriko Gotoh
Prominent expression of FRS2beta protein in neural cells and its association with intracellular vesicles.
FEBS letters 2009;583(4):807-14.
2009: Shintaro Yanagimoto; Keita Tatsuno; Shu Okugawa; Takatoshi Kitazawa; Kunihisa Tsukada; Kazuhiko Koike; Tatsuhiko Kodama; Satoshi Kimura; Yoshikazu Shibasaki; Yasuo Ota
A single amino acid of toll-like receptor 4 that is pivotal for its signal transduction and subcellular localization.
The Journal of biological chemistry 2009;284(6):3513-20.
2009: Iori Sakakibara; Takahiro Fujino; Makoto Ishii; Toshiya Tanaka; Tatsuo Shimosawa; Shinji Miura; Wei Zhang; Yuka Tokutake; Joji Yamamoto; Mutsumi Awano; Satoshi Iwasaki; Toshiyuki Motoike; Masashi Okamura; Takeshi Inagaki; Kiyoshi Kita; Osamu Ezaki; Makoto Naito; Tomoyuki Kuwaki; Shigeru Chohnan; Tokuo T Yamamoto; Robert E Hammer; Tatsuhiko Kodama; Masashi Yanagisawa; Juro Sakai
Fasting-induced hypothermia and reduced energy production in mice lacking acetyl-CoA synthetase 2.
Cell metabolism 2009;9(2):191-202.
2009: So Takegoshi; Shuying Jiang; Riuko Ohashi; Alexander S Savchenko; Hiroko Iwanari; Toshiya Tanaka; Go Hasegawa; Takao Hamakubo; Tatsuhiko Kodama; Makoto Naito
Protein expression of nuclear receptors in human and murine tissues.
Pathology international 2009;59(2):61-72.
2008: Mika Sugai; Hajime Umezu; Takashi Yamamoto; Shuying Jiang; Hiroko Iwanari; Toshiya Tanaka; Takao Hamakubo; Tatsuhiko Kodama; Makoto Naito
Expression of hepatocyte nuclear factor 4 alpha in primary ovarian mucinous tumors.
Pathology international 2008;58(11):681-6.
2008: Yuichi Torisu; Akira Watanabe; Aya Nonaka; Yutaka Midorikawa; Makuuchi Masatoshi; Takahiro Shimamura; Haruhiko Sugimura; Atsushi Niida; Tetsu Akiyama; Hiroko Iwanari; Tatsuhiko Kodama; Mikio Zeniya; Hiroyuki Aburatani
Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF.
Cancer science 2008;99(6):1139-46.
2008: Hiroto Ohguchi; Toshiya Tanaka; Aoi Uchida; Kenta Magoori; Hiromi Kudo; Insook Kim; Kenji Daigo; Iori Sakakibara; Masashi Okamura; Hideo Harigae; Takeshi Sasaki; Timothy F Osborne; Frank J Gonzalez; Takao Hamakubo; Tatsuhiko Kodama; Juro Sakai
Hepatocyte nuclear factor 4alpha contributes to thyroid hormone homeostasis by cooperatively regulating the type 1 iodothyronine deiodinase gene with GATA4 and Kruppel-like transcription factor 9.
Molecular and cellular biology 2008;28(12):3917-31.
2008: Toshiko Sakihama; Kazuyuki Masuda; Takato Sato; Takefumi Doi; Tatsuhiko Kodama; Takao Hamakubo
Functional reconstitution of G-protein-coupled receptor-mediated adenylyl cyclase activation by a baculoviral co-display system.
Journal of biotechnology 2008;135(1):28-33.
2008: As Savchenko; M Imamura; Riuko Ohashi; Shuying Jiang; Takashi Kawasaki; Go Hasegawa; I Emura; Hiroko Iwanari; Mina Sagara; Toshiya Tanaka; Takao Hamakubo; Tatsuhiko Kodama; Makoto Naito
Expression of pentraxin 3 (PTX3) in human atherosclerotic lesions.
The Journal of pathology 2008;215(1):48-55.
2008: Masahiro Shinohara; Takako Koga; Kazuo Okamoto; Shinya Sakaguchi; Kimiko Arai; Hisataka Yasuda; Toshiyuki Takai; Tatsuhiko Kodama; Tomohiro Morio; Raif S Geha; Daisuke Kitamura; Tomohiro Kurosaki; Wilfried Ellmeier; Hiroshi Takayanagi
Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.
Cell 2008;132(5):794-806.
2007: Akira Sugiyama; Youichiro Wada; Akashi Izumi; Mika Kobayashi; Kohro Takahide; C Reid Patrick; Takao Hamakubo; Tatsuhiko Kodama
Transcriptional activation by hypoxia and low-density lipoprotein loading in cultured vascular smooth muscle cells.
Journal of atherosclerosis and thrombosis 2007;14(5):226-34.
2007: Teppei Morikawa; Akira Sugiyama; Haruki Kume; Satoshi Ota; Takeshi Kashima; Kyoichi Tomita; Tadaichi Kitamura; Tatsuhiko Kodama; Masashi Fukayama; Hiroyuki Aburatani
Identification of Toll-like receptor 3 as a potential therapeutic target in clear cell renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(19):5703-9.
2007: Masaru Imamura; Takashi Kawasaki; Alexander S Savchenko; Riuko Ohashi; Shuying Jiang; Kyoko Miyamoto; Yukio Ito; Hiroko Iwanari; Mina Sagara; Toshiya Tanaka; Takao Hamakubo; Tatsuhiko Kodama; Makoto Uchiyama; Makoto Naito
Lipopolysaccharide induced expression of pentraxin 3 in human neutrophils and monocyte-derived macrophages.
Cellular immunology 2007;248(2):86-94.
2007: Toshiya Tanaka; Juro Sakai; Tatsuhiko Kodama
[Bile acids and control of lipid metabolism].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 7():557-63.
2007: Akinori Takaoka; Zhichao Wang; Myoung Kwon Choi; Hideyuki Yanai; Hideo Negishi; Tatsuma Ban; Yan Lu; Makoto Miyagishi; Tatsuhiko Kodama; Kenya Honda; Yusuke Ohba; Tadatsugu Taniguchi
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.
Nature 2007;448(7152):501-5.
2007: Sae Ochi; Masahiro Shinohara; kojiro sato; Hans-Jürgen Gober; Takako Koga; Tatsuhiko Kodama; Toshiyuki Takai; Nobuyuki Miyasaka; Hiroshi Takayanagi
Pathological role of osteoclast costimulation in arthritis-induced bone loss.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(27):11394-9.
2007: Haruhisa Iguchi; Yasuyo Urashima; Yosuke Inagaki; Yukio Ikeda; Masashi Okamura; Toshiya Tanaka; Aoi Uchida; Tokuo T Yamamoto; Tatsuhiko Kodama; Juro Sakai
SOX6 suppresses cyclin D1 promoter activity by interacting with beta-catenin and histone deacetylase 1, and its down-regulation induces pancreatic beta-cell proliferation.
The Journal of biological chemistry 2007;282(26):19052-61.
2007: Koichi Sumi; Toshiya Tanaka; Aoi Uchida; Kenta Magoori; Yasuyo Urashima; Riuko Ohashi; Hiroto Ohguchi; Masashi Okamura; Hiromi Kudo; Kenji Daigo; Takashi Maejima; Noriaki Kojima; Iori Sakakibara; Shuying Jiang; Go Hasegawa; Insook Kim; Timothy F Osborne; Makoto Naito; Frank J Gonzalez; Takao Hamakubo; Tatsuhiko Kodama; Juro Sakai
Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8.
Molecular and cellular biology 2007;27(12):4248-60.
2007: Azusa Sakamoto; Takashi Kawasaki; Toshihiro Kazawa; Riuko Ohashi; Shuying Jiang; Takashi Maejima; Toshiya Tanaka; Hiroko Iwanari; Takao Hamakubo; Juro Sakai; Tatsuhiko Kodama; Makoto Naito
Expression of liver X receptor alpha in rat fetal tissues at different developmental stages.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007;55(6):641-9.
2007: Patrick C Reid; Yasuomi Urano; Tatsuhiko Kodama; Takao Hamakubo
Alzheimer's disease: cholesterol, membrane rafts, isoprenoids and statins.
Journal of cellular and molecular medicine 2007;11(3):383-92.
2007: Ryoichi Saitoh; Toshihiko Ohtomo; Yoshiki Yamada; Nobuo Kamada; Jun-ichi Nezu; Naoki Kimura; Shin-ichi Funahashi; Koh Furugaki; Takeshi Yoshino; Yosuke Kawase; Atsuhiko Kato; Otoya Ueda; Kou-ichi Jishage; Masami Suzuki; Ryouichi Fukuda; Masahiro Arai; Hiroko Iwanari; Kazuaki Takahashi; Toshiko Sakihama; Iwao Ohizumi; Tatsuhiko Kodama; Masayuki Tsuchiya; Takao Hamakubo
Viral envelope protein gp64 transgenic mouse facilitates the generation of monoclonal antibodies against exogenous membrane proteins displayed on baculovirus.
Journal of immunological methods 2007;322(1-2):104-17.
2007: Eiji Warabi; Wakako Takabe; Takashi Minami; Kenji Inoue; Ken Itoh; Masayuki Yamamoto; Tetsuro Ishii; Tatsuhiko Kodama; Noriko Noguchi
Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: role of reactive oxygen/nitrogen species.
Free radical biology & medicine 2007;42(2):260-9.
2007: Kenji Inoue; Akira Sugiyama; Patrick C Reid; Yukio Ito; Katsumi Miyauchi; Sei Mukai; Mina Sagara; Kyoko Miyamoto; Hirokazu Satoh; Isao Kohno; Takeshi Kurata; Hiroshi Ota; Alberto Mantovani; Takao Hamakubo; Hiroyuki Daida; Tatsuhiko Kodama
Establishment of a high sensitivity plasma assay for human pentraxin3 as a marker for unstable angina pectoris.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(1):161-7.
2006: Yingqiu Guo; Yongxin Chen; Hirotaka Ito; Akira Watanabe; Xijin Ge; Tatsuhiko Kodama; Hiroyuki Aburatani
Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma.
Gene 2006;384():51-61.
2006: kojiro sato; Ayako Suematsu; Tomoki Nakashima; Sayaka Takemoto-Kimura; Kazuhiro Aoki; Yasuyuki Morishita; Hiroshi Asahara; Keiichi Ohya; Akira Yamaguchi; Toshiyuki Takai; Tatsuhiko Kodama; Talal A Chatila; Haruhiko Bito; Hiroshi Takayanagi
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway.
Nature medicine 2006;12(12):1410-6.
2006: Kenji Inoue; Mika Kobayashi; Kiichiro Yano; Mai Miura; Akashi Izumi; Chikage Mataki; Takeshi Doi; Takao Hamakubo; Patrick C Reid; David A Hume; Minoru Yoshida; William C Aird; Tatsuhiko Kodama; Takashi Minami
Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(12):2652-9.
2006: kojiro sato; Ayako Suematsu; Kazuo Okamoto; Akira Yamaguchi; Yasuyuki Morishita; Yuho Kadono; Sakae Tanaka; Tatsuhiko Kodama; Shizuo Akira; Yoichiro Iwakura; Daniel J Cua; Hiroshi Takayanagi
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction.
The Journal of experimental medicine 2006;203(12):2673-82.
2006: Keiko Horiuchi; Michihisa Umetani; Takashi Minami; Hiroto Okayama; Shinji Takada; Masayuki Yamamoto; Hiroyuki Aburatani; Patrick C Reid; David E Housman; Takao Hamakubo; Tatsuhiko Kodama
Wilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(46):17278-83.
2006: Michiyo Hishinuma; K-I Ohashi; Naoko Yamauchi; Takeshi Kashima; Hiroshi Uozaki; Satoshi Ota; Tatsuhiko Kodama; Hiroyuki Aburatani; Masashi Fukayama
Hepatocellular oncofetal protein, glypican 3 is a sensitive marker for alpha-fetoprotein-producing gastric carcinoma.
Histopathology 2006;49(5):479-86.
2006: Naeko Shinozaki-Narikawa; Tatsuhiko Kodama; Yoshikazu Shibasaki
Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation.
Traffic (Copenhagen, Denmark) 2006;7(11):1539-50.
2006: Satoshi Ota; Michiyo Hishinuma; Naoko Yamauchi; Akiteru Goto; Teppei Morikawa; Tetsuya Fujimura; Tadaichi Kitamura; Tatsuhiko Kodama; Hiroyuki Aburatani; Masashi Fukayama
Oncofetal protein glypican-3 in testicular germ-cell tumor.
Virchows Archiv : an international journal of pathology 2006;449(3):308-14.
2006: Takashi Minami; Mai Miura; William C Aird; Tatsuhiko Kodama
Thrombin-induced autoinhibitory factor, Down syndrome critical region-1, attenuates NFAT-dependent vascular cell adhesion molecule-1 expression and inflammation in the endothelium.
The Journal of biological chemistry 2006;281(29):20503-20.
2006: Hirotaka Ito; Shin-ichi Funahashi; Naoko Yamauchi; Junji Shibahara; Yutaka Midorikawa; Shigeto Kawai; Yasuko Kinoshita; Akira Watanabe; Yoshitaka Hippo; Toshihiko Ohtomo; Hiroko Iwanari; Atsushi Nakajima; Makuuchi Masatoshi; Masashi Fukayama; Yuichi Hirata; Takao Hamakubo; Tatsuhiko Kodama; Masayuki Tsuchiya; Hiroyuki Aburatani
Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3257-64.
2006: Sadao Takahashi; Toshiya Tanaka; Tatsuhiko Kodama; Juro Sakai
Peroxisome proliferator-activated receptor delta (PPARdelta), a novel target site for drug discovery in metabolic syndrome.
Pharmacological research : the official journal of the Italian Pharmacological Society 2006;53(6):501-7.
2006: Nobuo Watanabe; Jaroslaw W Zmijewski; Wakako Takabe; Makiko Umezu-Goto; Claire Le Goffe; Azusa Sekine; Aimee Landar; Akira Watanabe; Junken Aoki; Hiroyuki Arai; Tatsuhiko Kodama; Michael P Murphy; Raman Kalyanaraman; Victor Darley-Usmar; Noriko Noguchi
Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells.
The American journal of pathology 2006;168(5):1737-48.
2006: Kenji Daigo; Sui Sugita; Yasuhiro Mochizuki; Hiroko Iwanari; Kanae Hiraishi; Kenjiro Miyano; Tatsuhiko Kodama; Takao Hamakubo
A simple hybridoma screening method for high-affinity monoclonal antibodies using the signal ratio obtained from time-resolved fluorescence assay.
Analytical biochemistry 2006;351(2):219-28.
2006: Toshiaki Tanaka; Shuying Jiang; H Hotta; K Takano; Hiroko Iwanari; Koichi Sumi; Kenji Daigo; Riuko Ohashi; M Sugai; C Ikegame; H Umezu; Y Hirayama; Yutaka Midorikawa; Yoshitaka Hippo; Akira Watanabe; Yasutoshi Uchiyama; Go Hasegawa; Pc Reid; Hiroyuki Aburatani; Takao Hamakubo; Juro Sakai; Makoto Naito; Tatsuhiko Kodama
Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer.
The Journal of pathology 2006;208(5):662-72.
2006: Ryoichi Saitoh; Toshihiko Ohtomo; Yukio Ito; Jun-ichi Nezu; Naoki Kimura; Shin-ichi Funahashi; Yoshinori Aso; Iwao Ohizumi; Tatsuhiko Kodama; Takao Hamakubo; Masayuki Tsuchiya
Recovery of functional peptide transporter PepT1 in budded baculovirus fraction.
Protein expression and purification 2006;46(1):130-5.
2006: Yongxin Chen; Yingqiu Guo; Xijin Ge; Hirotaka Itoh; Akira Watanabe; Takeshi Fujiwara; Tatsuhiko Kodama; Hiroyuki Aburatani
Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers.
Biochemical and biophysical research communications 2006;340(3):758-66.
2006: Wakako Takabe; Naeko Matsukawa; Tatsuhiko Kodama; Keiji Tanaka; Noriko Noguchi
Chemical structure-dependent gene expression of proteasome subunits via regulation of the antioxidant response element.
Free radical research 2006;40(1):21-30.
2005: Naoko Yamauchi; Akira Watanabe; Michiyo Hishinuma; Ken-Ichi Ohashi; Yutaka Midorikawa; Yasuyuki Morishita; Toshiro Niki; Junji Shibahara; Masaya Mori; Makuuchi Masatoshi; Yoshitaka Hippo; Tatsuhiko Kodama; Hiroko Iwanari; Hiroyuki Aburatani; Masashi Fukayama
The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(12):1591-8.
2005: Haruhisa Iguchi; Yukio Ikeda; Masashi Okamura; Toshiya Tanaka; Yasuyo Urashima; Hiroto Ohguchi; Shinobu Takayasu; Noriaki Kojima; Satoshi Iwasaki; Riuko Ohashi; Shuying Jiang; Go Hasegawa; Ryoichi X Ioka; Kenta Magoori; Koichi Sumi; Takashi Maejima; Aoi Uchida; Makoto Naito; Timothy F Osborne; Masashi Yanagisawa; Tokuo T Yamamoto; Tatsuhiko Kodama; Juro Sakai
SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice.
The Journal of biological chemistry 2005;280(45):37669-80.
2005: Yukio Ikeda; Haruhisa Iguchi; Masanori Nakata; Ryoichi X Ioka; Toshiya Tanaka; Satoshi Iwasaki; Kenta Magoori; Shinobu Takayasu; Tokuo T Yamamoto; Tatsuhiko Kodama; Toshihiko Yada; Takeshi Sakurai; Masashi Yanagisawa; Juro Sakai
Identification of N-arachidonylglycine, U18666A, and 4-androstene-3,17-dione as novel insulin Secretagogues.
Biochemical and biophysical research communications 2005;333(3):778-86.
2005: Takako Koga; Yuichi Matsui; Masataka Asagiri; Tatsuhiko Kodama; Benoit de Crombrugghe; Kazuhisa Nakashima; Hiroshi Takayanagi
NFAT and Osterix cooperatively regulate bone formation.
Nature medicine 2005;11(8):880-5.
2005: Chiyuki Akiyama; Naeko Shinozaki-Narikawa; Takatoshi Kitazawa; Takao Hamakubo; Tatsuhiko Kodama; Yoshikazu Shibasaki
Phosphatidylinositol-4-phosphate 5-kinase gamma is associated with cell-cell junction in A431 epithelial cells.
Cell biology international 2005;29(7):514-20.
2005: Takahiro Shimamura; Hirotaka Ito; Junji Shibahara; Akira Watanabe; Yoshitaka Hippo; Hirokazu Taniguchi; Yongxin Chen; Takeshi Kashima; Toshihiko Ohtomo; Fumihiko Tanioka; Hiroko Iwanari; Tatsuhiko Kodama; Teruhisa Kazui; Haruhiko Sugimura; Masashi Fukayama; Hiroyuki Aburatani
Overexpression of MUC13 is associated with intestinal-type gastric cancer.
Cancer science 2005;96(5):265-73.
2005: Yasuomi Urano; Ikuo Hayashi; Noriko Isoo; Patrick C Reid; Yoshikazu Shibasaki; Noriko Noguchi; Taisuke Tomita; Takeshi Iwatsubo; Takao Hamakubo; Tatsuhiko Kodama
Association of active gamma-secretase complex with lipid rafts.
Journal of lipid research 2005;46(5):904-12.
2005: Yuichi Matsui; Akio Saiura; Yasuhiko Sugawara; Tatsuhiko Kodama; Makuuchi Masatoshi
[Appliance of microarray technology to clinical organ transplantation].
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2005;28(2):73-8.
2005: Makoto Tachibana; Jun Ueda; Mikiko Fukuda; Naoki Takeda; Tsutomu Ohta; Hiroko Iwanari; Toshiko Sakihama; Tatsuhiko Kodama; Takao Hamakubo; Yoichi Shinkai
Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9.
Genes & development 2005;19(7):815-26.
2005: Shin-ichi Fukumoto; Naoko Yamauchi; Hisashi Moriguchi; Yoshitaka Hippo; Akira Watanabe; Junji Shibahara; Hirokazu Taniguchi; Shumpei Ishikawa; Hirotaka Ito; Shogo Yamamoto; Hiroko Iwanari; Mitsugu Hironaka; Yuichi Ishikawa; Toshiro Niki; Yasunori Sohara; Tatsuhiko Kodama; Masaharu Nishimura; Masashi Fukayama; Hirotoshi Dosaka-Akita; Hiroyuki Aburatani
Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(5):1776-85.
2005: Yuichiro Watanabe; Shuying Jiang; Wakako Takabe; Riuko Ohashi; Toshiya Tanaka; Yasutoshi Uchiyama; Keiko Katsumi; Hiroko Iwanari; Noriko Noguchi; Makoto Naito; Takao Hamakubo; Tatsuhiko Kodama
Expression of the LXRalpha protein in human atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(3):622-7.
2005: Mika Kobayashi; Kenji Inoue; Eiji Warabi; Takashi Minami; Tatsuhiko Kodama
A simple method of isolating mouse aortic endothelial cells.
Journal of atherosclerosis and thrombosis 2005;12(3):138-42.
2005: Shigeru Morikawa; Takeshi Murakami; Hiroyuki Yamazaki; Akashi Izumi; Yasushi Saito; Takao Hamakubo; Tatsuhiko Kodama
Analysis of the global RNA expression profiles of skeletal muscle cells treated with statins.
Journal of atherosclerosis and thrombosis 2005;12(3):121-31.
2004: Takashi Minami; Keiko Horiuchi; Mai Miura; Md Ruhul Abid; Wakako Takabe; Noriko Noguchi; Kohro Takahide; Xijin Ge; Hiroyuki Aburatani; Takao Hamakubo; Tatsuhiko Kodama; William C Aird
Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis.
The Journal of biological chemistry 2004;279(48):50537-54.
2004: Ikuo Hayashi; Yasuomi Urano; Ryouichi Fukuda; Noriko Isoo; Tatsuhiko Kodama; Takao Hamakubo; Taisuke Tomita; Takeshi Iwatsubo
Selective reconstitution and recovery of functional gamma-secretase complex on budded baculovirus particles.
The Journal of biological chemistry 2004;279(36):38040-6.
2004: Nanako Itoh; Yasukazu Yoshida; Mieko Hayakawa; Noriko Noguchi; Tatsuhiko Kodama; Osamu Cynshi; Etsuo Niki
Inhibition of plasma lipid peroxidation by anti-atherogenic antioxidant BO-653, 2,3-dihydro-5-hydroxy-4,6-di-tert-butyl-2,2-dipentylbenzofuran.
Biochemical pharmacology 2004;68(5):813-8.
2004: Eiji Warabi; Youichiro Wada; Hiroko Kajiwara; Mika Kobayashi; Nobuko Koshiba; Toshiaki Hisada; Masahiro Shibata; Joji Ando; Masatoshi Tsuchiya; Tatsuhiko Kodama; Noriko Noguchi
Effect on endothelial cell gene expression of shear stress, oxygen concentration, and low-density lipoprotein as studied by a novel flow cell culture system.
Free radical biology & medicine 2004;37(5):682-94.
2004: Wakako Takabe; Yoshikatsu Kanai; Arthit Chairoungdua; Noriyuki Shibata; Sono Toi; Makio Kobayashi; Tatsuhiko Kodama; Noriko Noguchi
Lysophosphatidylcholine enhances cytokine production of endothelial cells via induction of L-type amino acid transporter 1 and cell surface antigen 4F2.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(9):1640-5.
2004: Akira Sato; Shinya Kishida; Toshiya Tanaka; Akira Kikuchi; Tatsuhiko Kodama; Makoto Asashima; Ryuichi Nishinakamura
Sall1, a causative gene for Townes-Brocks syndrome, enhances the canonical Wnt signaling by localizing to heterochromatin.
Biochemical and biophysical research communications 2004;319(1):103-13.
2004: Takashi Minami; Takeshi Murakami; Keiko Horiuchi; Mai Miura; Tamio Noguchi; Jun-ichi Miyazaki; Takao Hamakubo; William C Aird; Tatsuhiko Kodama
Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling.
The Journal of biological chemistry 2004;279(20):20626-35.
2004: Joji Yamamoto; Yukio Ikeda; Haruhisa Iguchi; Takahiro Fujino; Toshiya Tanaka; Hiroshi Asaba; Satoshi Iwasaki; Ryoichi X Ioka; Izumi W Kaneko; Kenta Magoori; Sadao Takahashi; Toshiyuki Mori; Hiroshi Sakaue; Tatsuhiko Kodama; Masashi Yanagisawa; Tokuo T Yamamoto; Sadayoshi Ito; Juro Sakai
A Kruppel-like factor KLF15 contributes fasting-induced transcriptional activation of mitochondrial acetyl-CoA synthetase gene AceCS2.
The Journal of biological chemistry 2004;279(17):16954-62.
2004: Takako Koga; Masanori Inui; Kazuya Inoue; Sunhwa Kim; Ayako Suematsu; Eiji Kobayashi; Toshio Iwata; Hiroshi Ohnishi; Takashi Matozaki; Tatsuhiko Kodama; Tadatsugu Taniguchi; Hiroshi Takayanagi; Toshiyuki Takai
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis.
Nature 2004;428(6984):758-63.
2004: Yoshitaka Hippo; Kiyotaka Watanabe; Akira Watanabe; Yutaka Midorikawa; Shogo Yamamoto; Sayoko Ihara; Susumu Tokita; Hiroko Iwanari; Yukio Ito; Kiyotaka Nakano; Jun-ichi Nezu; Hiroyuki Tsunoda; Takeshi Yoshino; Iwao Ohizumi; Masayuki Tsuchiya; Shin Ohnishi; Makuuchi Masatoshi; Takao Hamakubo; Tatsuhiko Kodama; Hiroyuki Aburatani
Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma.
Cancer research 2004;64(7):2418-23.
2004: Makoto Urushibara; Hiroshi Takayanagi; Takako Koga; Sunhwa Kim; Miho Isobe; Yasuyuki Morishita; Takumi Nakagawa; Monika Löeffler; Tatsuhiko Kodama; Hisashi Kurosawa; Tadatsugu Taniguchi
The antirheumatic drug leflunomide inhibits osteoclastogenesis by interfering with receptor activator of NF-kappa B ligand-stimulated induction of nuclear factor of activated T cells c1.
Arthritis and rheumatism 2004;50(3):794-804.
2004: Nobutaka Kawahara; Yan Wang; Akitake Mukasa; Kazuhide Furuya; Tatsuya Shimizu; Takao Hamakubo; Hiroyuki Aburatani; Tatsuhiko Kodama; Takaaki Kirino
Genome-wide gene expression analysis for induced ischemic tolerance and delayed neuronal death following transient global ischemia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(2):212-23.
2004: Kohro Takahide; Toshiya Tanaka; Takeshi Murakami; Yoichiro Wada; Hiroyuki Aburatani; Takao Hamakubo; Tatsuhiko Kodama
A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage.
Journal of atherosclerosis and thrombosis 2004;11(2):88-97.
2004: Shigeru Morikawa; Wakako Takabe; Chikage Mataki; Yoichiro Wada; Akashi Izumi; Yasushi Saito; Takao Hamakubo; Tatsuhiko Kodama
Global analysis of RNA expression profile in human vascular cells treated with statins.
Journal of atherosclerosis and thrombosis 2004;11(2):62-72.
2004: Takashi Minami; Akira Sugiyama; Sheng-Qian Wu; Ruhul Abid; Tatsuhiko Kodama; William C Aird
Thrombin and phenotypic modulation of the endothelium.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(1):41-53.
2003: Toshiya Tanaka; Joji Yamamoto; Satoshi Iwasaki; Hiroshi Asaba; Hiroki Hamura; Yukio Ikeda; Mitsuhiro Watanabe; Kenta Magoori; Ryoichi X Ioka; Keisuke Tachibana; Yuichiro Watanabe; Yasutoshi Uchiyama; Koichi Sumi; Haruhisa Iguchi; Sadayoshi Ito; Takefumi Doi; Takao Hamakubo; Makoto Naito; Johan Auwerx; Masashi Yanagisawa; Tatsuhiko Kodama; Juro Sakai
Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15924-9.
2003: Akira Watanabe; Yoshitaka Hippo; Hirokazu Taniguchi; Hiroko Iwanari; Masakazu Yashiro; Kosei Hirakawa; Tatsuhiko Kodama; Hiroyuki Aburatani
An opposing view on WWOX protein function as a tumor suppressor.
Cancer research 2003;63(24):8629-33.
2003: Yuichi Matsui; Akio Saiura; Yasuhiko Sugawara; Masataka Sata; Katsutoshi Naruse; Hideo Yagita; Kohro Takahide; Chikage Mataki; Akashi Izumi; Takuhiro Yamaguchi; Takashi Minami; Toshiko Sakihama; Sayoko Ihara; Hiroyuki Aburatani; Takao Hamakubo; Tatsuhiko Kodama; Makuuchi Masatoshi
Identification of gene expression profile in tolerizing murine cardiac allograft by costimulatory blockade.
Physiological genomics 2003;15(3):199-208.
2003: Takashi Minami; Jan Albert Kuivenhoven; Valerie Evans; Tatsuhiko Kodama; Robert D Rosenberg; William C Aird
Ets motifs are necessary for endothelial cell-specific expression of a 723-bp Tie-2 promoter/enhancer in Hprt targeted transgenic mice.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(11):2041-7.
2003: Yuko Okimoto; Eiji Warabi; Youichiro Wada; Etsuo Niki; Tatsuhiko Kodama; Noriko Noguchi
A novel method of following oxidation of low-density lipoprotein using a sensitive fluorescent probe, diphenyl-1-pyrenylphosphine.
Free radical biology & medicine 2003;35(6):576-85.
2003: Yasuomi Urano; Mineko Yamaguchi; Ryouichi Fukuda; Kazuyuki Masuda; Kazuaki Takahashi; Yasutoshi Uchiyama; Hiroko Iwanari; Shu-Ying Jiang; Makoto Naito; Tatsuhiko Kodama; Takao Hamakubo
A novel method for viral display of ER membrane proteins on budded baculovirus.
Biochemical and biophysical research communications 2003;308(1):191-6.
2003: Kazuyuki Masuda; Hiroshi Itoh; Toshiko Sakihama; Chiyuki Akiyama; Kazuaki Takahashi; Ryouichi Fukuda; Takehiko Yokomizo; Takao Shimizu; Tatsuhiko Kodama; Takao Hamakubo
A combinatorial G protein-coupled receptor reconstitution system on budded baculovirus. Evidence for Galpha and Galphao coupling to a human leukotriene B4 receptor.
The Journal of biological chemistry 2003;278(27):24552-62.
2003: Kunio Tamura; Yoshiaki Kato; Akira Ishikawa; Yasuharu Kato; Motomu Himori; Mitsutaka Yoshida; Yoshiaki Takashima; Tsukasa Suzuki; Yoshiki Kawabe; Osamu Cynshi; Tatsuhiko Kodama; Etsuo Niki; Makoto Shimizu
Design and synthesis of 4,6-di-tert-butyl-2,3-dihydro-5-benzofuranols as a novel series of antiatherogenic antioxidants.
Journal of medicinal chemistry 2003;46(14):3083-93.
2003: Noriko Noguchi; Ryuhei Hanyu; Aya Nonaka; Yuko Okimoto; Tatsuhiko Kodama
Inhibition of THP-1 cell adhesion to endothelial cells by alpha-tocopherol and alpha-tocotrienol is dependent on intracellular concentration of the antioxidants.
Free radical biology & medicine 2003;34(12):1614-20.
2003: Yutaka Midorikawa; Shumpei Ishikawa; Hiroko Iwanari; Takeshi Imamura; Hirohiko Sakamoto; Kohei Miyazono; Tatsuhiko Kodama; Makuuchi Masatoshi; Hiroyuki Aburatani
Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling.
International journal of cancer. Journal international du cancer 2003;103(4):455-65.
2003: Norihiko Ohura; Kimiko Yamamoto; Shigeru Ichioka; Takaaki Sokabe; Hideki Nakatsuka; Atsushi Baba; Masahiro Shibata; Takashi Nakatsuka; Kiyonori Harii; Youichiro Wada; Kohro Takahide; Tatsuhiko Kodama; Joji Ando
Global analysis of shear stress-responsive genes in vascular endothelial cells.
Journal of atherosclerosis and thrombosis 2003;10(5):304-13.
2002: Hiroshi Takayanagi; Sunhwa Kim; Takako Koga; Hiroshi Nishina; Masashi Isshiki; Hiroki Yoshida; Akio Saiura; Miho Isobe; Taeko Yokochi; Jun-Ichiro Inoue; Erwin F Wagner; Tak W Mak; Tatsuhiko Kodama; Tadatsugu Taniguchi
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts.
Developmental cell 2002;3(6):889-901.
2002: Yasukazu Yoshida; Noriko Noguchi; Akira Watanabe; Yoshihide Iwaki; Makoto Yanagisawa; Tatsuhiko Kodama; Osamu Cynshi; Etsuo Niki
Antioxidant action of 2,2,4,6-tetra-substituted 2,3-dihydro-5-hydroxybenzofuran against lipid peroxidation: effects of substituents and side chain.
Free radical research 2002;36(11):1171-8.
2002: Akio Saiura; Yasuhiko Sugawara; Yasushi Harihara; Masataka Sata; Takao Hamakubo; Tatsuhiko Kodama; Makuuchi Masatoshi
Gene expression profile during acute rejection in rat-to-mouse concordant cardiac xenograft by means of DNA microarray.
Transplant international : official journal of the European Society for Organ Transplantation 2002;15(11):535-40.
2002: Youichiro Wada; Akira Sugiyama; Takashi Yamamoto; Makoto Naito; Noriko Noguchi; Shinji Yokoyama; Maki Tsujita; Yoshiki Kawabe; Mika Kobayashi; Akashi Izumi; Kohro Takahide; Toshiya Tanaka; Hirokazu Taniguchi; Hidenori Koyama; Ken-ichi Hirano; Shizuya Yamashita; Yuji Matsuzawa; Etsuo Niki; Takao Hamakubo; Tatsuhiko Kodama
Lipid accumulation in smooth muscle cells under LDL loading is independent of LDL receptor pathway and enhanced by hypoxic conditions.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(10):1712-9.
2002: Yutaka Midorikawa; Shuichi Tsutsumi; Hirokazu Taniguchi; Masami Ishii; Yuko Kobune; Tatsuhiko Kodama; Makuuchi Masatoshi; Hiroyuki Aburatani
Identification of genes associated with dedifferentiation of hepatocellular carcinoma with expression profiling analysis.
Japanese journal of cancer research : Gann 2002;93(6):636-43.
2002: Akio Saiura; Kohro Takahide; Takashi Yamamoto; Akashi Izumi; Yoichiro Wada; Hiroyuki Aburatani; Yasuhiko Sugawara; Takao Hamakubo; Tadatsugu Taniguchi; Makoto Naito; Tatsuhiko Kodama; Makuuchi Masatoshi
Detection of an up-regulation of a group of chemokine genes in murine cardiac allograft in the absence of interferon-gamma by means of DNA microarray.
Transplantation 2002;73(9):1480-6.
2002: Kenji Inoue; Osamu Cynshi; Yoshiki Kawabe; Minako Nakamura; Katsumi Miyauchi; Tohoru Kimura; Hiroyuki Daida; Takao Hamakubo; Hiroshi Yamaguchi; Tatsuhiko Kodama
Effect of BO-653 and probucol on c-MYC and PDGF-A messenger RNA of the iliac artery after balloon denudation in cholesterol-fed rabbits.
Atherosclerosis 2002;161(2):353-63.
2002: Kouetsu Ogasawara; Shigeaki Hida; Youmin Weng; Akio Saiura; kojiro sato; Hiroshi Takayanagi; Shinya Sakaguchi; Taeko Yokochi; Tatsuhiko Kodama; Makoto Naitoh; Julie A De Martino; Tadatsugu Taniguchi
Requirement of the IFN-alpha/beta-induced CXCR3 chemokine signalling for CD8+ T cell activation.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(3):309-20.
2002: Toshiya Tanaka; Tetsu Takeno; Yuichiro Watanabe; Yasutoshi Uchiyama; Takeshi Murakami; Hisahiko Yamashita; Akifumi Suzuki; Rie Aoi; Hiroko Iwanari; Shu-Ying Jiang; Makoto Naito; Keisuke Tachibana; Takefumi Doi; Andrew I Shulman; David J Mangelsdorf; Raphael Reiter; Johan Auwerx; Takao Hamakubo; Tatsuhiko Kodama
The generation of monoclonal antibodies against human peroxisome proliferator-activated receptors (PPARs).
Journal of atherosclerosis and thrombosis 2002;9(5):233-42.
2002: Hiromi Wada; Kiyoshi Hashimoto; Youichiro Wada; Mika Kobayashi; Akashi Izumi; Akira Sugiyama; Kohro Takahide; Takao Hamakubo; Tatsuhiko Kodama
Extensive oligonucleotide microarray transcriptome analysis of the rat cerebral artery and arachnoid tissue.
Journal of atherosclerosis and thrombosis 2002;9(5):224-32.
2002: Shigeru Morikawa; Wakako Takabe; Chikage Mataki; Toru Kanke; Takahiro Itoh; Youichiro Wada; Akashi Izumi; Yasushi Saito; Takao Hamakubo; Tatsuhiko Kodama
The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cells.
Journal of atherosclerosis and thrombosis 2002;9(4):178-83.
2002: Yoshitaka Hippo; Hirokazu Taniguchi; Shuichi Tsutsumi; Naoko Machida; Ja-Mun Chong; Masashi Fukayama; Tatsuhiko Kodama; Hiroyuki Aburatani
Global gene expression analysis of gastric cancer by oligonucleotide microarrays.
Cancer research 2002;62(1):233-40.
2001: S Kosaka; Sadao Takahashi; Katsuhiko Masamura; Hideo Kanehara; Juro Sakai; Gen Tohda; E Okada; Koji Oida; T Iwasaki; Hiroaki Hattori; Tatsuhiko Kodama; Tokuo T Yamamoto; Isamu Miyamori
Evidence of macrophage foam cell formation by very low-density lipoprotein receptor: interferon-gamma inhibition of very low-density lipoprotein receptor expression and foam cell formation in macrophages.
Circulation 2001;103(8):1142-7.
2001: Yoshitaka Hippo; Masakazu Yashiro; M Ishii; Hirokazu Taniguchi; Shuichi Tsutsumi; Kosei Hirakawa; Tatsuhiko Kodama; Hiroyuki Aburatani
Differential gene expression profiles of scirrhous gastric cancer cells with high metastatic potential to peritoneum or lymph nodes.
Cancer research 2001;61(3):889-95.
1999: Takafumi Ishida; R Takashima; Masashi Fukayama; C Hamada; Yoshitaka Hippo; T Fujii; S Moriyama; C Matsuba; Yutaka Nakahori; H Morita; Y Yazaki; Tatsuhiko Kodama; S Nishimura; Hiroyuki Aburatani
New DNA polymorphisms of human MMH/OGG1 gene: prevalence of one polymorphism among lung-adenocarcinoma patients in Japanese.
International journal of cancer. Journal international du cancer 1999;80(1):18-21.
1999: Takafumi Ishida; Yoshitaka Hippo; Yutaka Nakahori; Ikumi Matsushita; Tatsuhiko Kodama; S Nishimura; Hiroyuki Aburatani
Structure and chromosome location of human OGG1.
Cytogenetics and cell genetics 1999;85(3-4):232-6.
1997: Hiroyuki Aburatani; Yoshitaka Hippo; Takafumi Ishida; R Takashima; C Matsuba; Tatsuhiko Kodama; M Takao; A Yasui; Kaneyoshi Yamamoto; M Asano
Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue.
Cancer research 1997;57(11):2151-6.
1997: Yasuo Terauchi; K Iwamoto; H Tamemoto; Kajuro Komeda; Chiaki Ishii; Y Kanazawa; N Asanuma; T Aizawa; Yasuo Akanuma; Kazuki Yasuda; Tatsuhiko Kodama; Kazuyuki Tobe; Yoshio Yazaki; Takashi Kadowaki
Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease.
The Journal of clinical investigation 1997;99(5):861-6.
1988: Y Ohta; T Masuda; Hajime Tsujimoto; K Ishikawa; Tatsuhiko Kodama; S Morikawa; M Nakai; S Honjo; M Hayami
Isolation of simian immunodeficiency virus from African green monkeys and seroepidemiologic survey of the virus in various non-human primates.
International journal of cancer. Journal international du cancer 1988;41(1):115-22.
1987: T Miura; Hajime Tsujimoto; M Fukasawa; Tatsuhiko Kodama; M Shibuya; A Hasegawa; M Hayami
Structural abnormality and over-expression of the myc gene in feline leukemias.
International journal of cancer. Journal international du cancer 1987;40(4):564-9.