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Roger Koeppe
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39
Andersen, Olaf
30
Greathouse, Denise
20
Killian, Antoinette
11
Providence, Lyndon
9
van der Wel, Patrick
6
de Planque, Maurits
4
Millett, Francis
4
de Kruijff, Ben
4
Jude, AR
4
Shungu, Dikoma
3
Lundbaek, Jens
3
Tape, Sonya
3
Liskamp, Rob
3
Strandberg, Erik
3
Morein, Sven
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All Publications
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2008: Vostrikov Vitaly V; Grant Christopher V; Daily Anna E; Opella Stanley J; Koeppe Roger E
Comparison of "Polarization inversion with spin exchange at magic angle" and "geometric analysis of labeled alanines" methods for transmembrane helix alignment.
Journal of the American Chemical Society 2008;130(38):12584-5.
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2008: Sun Haiyan; Greathouse Denise V; Andersen Olaf S; Koeppe Roger E
The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels.
The Journal of biological chemistry 2008;283(32):22233-43.
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2008: Holt Andrea; de Almeida Rodrigo F M; Nyholm Thomas K M; Loura Luís M S; Daily Anna E; Staffhorst Rutger W H M; Rijkers Dirk T S; Koeppe Roger E; Prieto Manuel; Killian J Antoinette
Is there a preferential interaction between cholesterol and tryptophan residues in membrane proteins?
Biochemistry 2008;47(8):2638-49.
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2008: Daily Anna E; Greathouse Denise V; van der Wel Patrick C A; Koeppe Roger E
Helical distortion in tryptophan- and lysine-anchored membrane-spanning alpha-helices as a function of hydrophobic mismatch: a solid-state deuterium NMR investigation using the geometric analysis of labeled alanines method.
Biophysical journal 2008;94(2):480-91.
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2007: Ingolfsson Helgi I; Koeppe Roger E; Andersen Olaf S
Curcumin is a modulator of bilayer material properties.
Biochemistry 2007;46(36):10384-91.
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2007: Bruno Michael J; Koeppe Roger E; Andersen Olaf S
Docosahexaenoic acid alters bilayer elastic properties.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9638-43.
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2007: van der Wel Patrick C A; Reed Nicole D; Greathouse Denise V; Koeppe Roger E
Orientation and motion of tryptophan interfacial anchors in membrane-spanning peptides.
Biochemistry 2007;46(25):7514-24.
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2007: Lindholm-Sethson Britta; Geladi Paul; Koeppe Roger E; Jonsson Oskar; Nilsson David; Nelson Andrew
Multivariate data analysis for enhanced interpretation of electrochemical impedance spectra of gramicidin-ion interactions in phospholipid monolayers.
Langmuir : the ACS journal of surfaces and colloids 2007;23(9):5029-32.
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2007: Andersen Olaf S; Bruno Michael J; Sun Haiyan; Koeppe Roger E
Single-molecule methods for monitoring changes in bilayer elastic properties.
Methods in molecular biology (Clifton, N.J.) 2007;400():543-70.
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2007: Andersen Olaf S; Koeppe Roger E
Bilayer thickness and membrane protein function: an energetic perspective.
Annual review of biophysics and biomolecular structure 2007;36():107-30.
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2006: Siegel D P; Cherezov V; Greathouse D V; Koeppe R E; Killian J Antoinette; Caffrey M
Transmembrane peptides stabilize inverted cubic phases in a biphasic length-dependent manner: implications for protein-induced membrane fusion.
Biophysical journal 2006;90(1):200-11.
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2005: Pulay Peter; Scherer Erin M; van der Wel Patrick C A; Koeppe Roger E
Importance of tensor asymmetry for the analysis of 2H NMR spectra from deuterated aromatic rings.
Journal of the American Chemical Society 2005;127(49):17488-93.
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2005: Lundbaek J A; Birn P; Tape S E; Toombes G E S; Søgaard R; Koeppe Roger E; Gruner S M; Hansen A J; Andersen O S
Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity.
Molecular pharmacology 2005;68(3):680-9.
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2005: Andersen Olaf S; Koeppe Roger E; Roux Benoît
Gramicidin channels.
IEEE transactions on nanobioscience 2005;4(1):10-20.
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2004: Suchyna Thomas M; Tape Sonya E; Koeppe Roger E; Andersen Olaf S; Sachs Frederick; Gottlieb Philip A
Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers.
Nature 2004;430(6996):235-40.
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2004: Strandberg Erik; Ozdirekcan Suat; Rijkers Dirk T S; van der Wel Patrick C A; Koeppe Roger E; Liskamp Rob M J; Killian J Antoinette
Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR.
Biophysical journal 2004;86(6):3709-21.
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2004: Lundbaek Jens A; Birn Pia; Hansen Anker J; Søgaard Rikke; Nielsen Claus; Girshman Jeffrey; Bruno Michael J; Tape Sonya E; Egebjerg Jan; Greathouse Denise V; Mattice Gwendolyn L; Koeppe Roger E; Andersen Olaf S
Regulation of sodium channel function by bilayer elasticity: the importance of hydrophobic coupling. Effects of Micelle-forming amphiphiles and cholesterol.
The Journal of general physiology 2004;123(5):599-621.
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2003: Hwang Tzyh-Chang; Koeppe Roger E; Andersen Olaf S
Genistein can modulate channel function by a phosphorylation-independent mechanism: importance of hydrophobic mismatch and bilayer mechanics.
Biochemistry 2003;42(46):13646-58.
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2003: Koeppe Roger E; Sun Haiyan; van der Wel Patrick C A; Scherer Erin M; Pulay Peter; Greathouse Denise V
Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations.
Journal of the American Chemical Society 2003;125(40):12268-76.
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2003: de Planque Maurits R R; Bonev Boyan B; Demmers Jeroen A A; Greathouse Denise V; Koeppe Roger E; Separovic Frances; Watts Anthony; Killian J Antoinette
Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions.
Biochemistry 2003;42(18):5341-8.
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2003: Goforth Robyn L; Chi Aung K; Greathouse Denise V; Providence Lyndon L; Koeppe Roger E; Andersen Olaf S
Hydrophobic coupling of lipid bilayer energetics to channel function.
The Journal of general physiology 2003;121(5):477-93.
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2003: Weiss Thomas M; van der Wel Patrick C A; Killian J Antoinette; Koeppe Roger E; Huang Huey W
Hydrophobic mismatch between helices and lipid bilayers.
Biophysical journal 2003;84(1):379-85.
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2002: van der Wel Patrick C A; Strandberg Erik; Killian J Antoinette; Koeppe Roger E
Geometry and intrinsic tilt of a tryptophan-anchored transmembrane alpha-helix determined by (2)H NMR.
Biophysical journal 2002;83(3):1479-88.
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2001: Demmers J A; van Duijn E; Haverkamp J; Greathouse D V; Koeppe R E; Heck A J; Killian J A
Interfacial positioning and stability of transmembrane peptides in lipid bilayers studied by combining hydrogen/deuterium exchange and mass spectrometry.
The Journal of biological chemistry 2001;276(37):34501-8.
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2001: de Planque M R; Goormaghtigh E; Greathouse D V; Koeppe R E; Kruijtzer J A; Liskamp R M; de Kruijff B; Killian J A
Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation.
Biochemistry 2001;40(16):5000-10.
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2000: Demmers J A; Haverkamp J; Heck A J; Koeppe R E; Killian J A
Electrospray ionization mass spectrometry as a tool to analyze hydrogen/deuterium exchange kinetics of transmembrane peptides in lipid bilayers.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3189-94.
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2000: van der Wel P C; Pott T; Morein S; Greathouse D V; Koeppe R E; Killian J A
Tryptophan-anchored transmembrane peptides promote formation of nonlamellar phases in phosphatidylethanolamine model membranes in a mismatch-dependent manner.
Biochemistry 2000;39(11):3124-33.
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2000: Koeppe R E; Hatchett J; Jude A R; Providence L L; Andersen O S; Greathouse D V
Neighboring aliphatic/aromatic side chain interactions between residues 9 and 10 in gramicidin channels.
Biochemistry 2000;39(9):2235-42.
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1999: Jude A R; Greathouse D V; Leister M C; Koeppe R E
Steric interactions of valines 1, 5, and 7 in [valine 5, D-alanine 8] gramicidin A channels.
Biophysical journal 1999;77(4):1927-35.
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1999: de Planque M R; Kruijtzer J A; Liskamp R M; Marsh D; Greathouse D V; Koeppe R E; de Kruijff B; Killian J A
Different membrane anchoring positions of tryptophan and lysine in synthetic transmembrane alpha-helical peptides.
The Journal of biological chemistry 1999;274(30):20839-46.
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1999: Cross T A; Arseniev A; Cornell B A; Davis J H; Killian J A; Koeppe R E; Nicholson L K; Separovic F; Wallace B A
Gramicidin channel controversy--revisited.
Nature structural biology 1999;6(7):610-1; discussion 611-2.
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1999: Andersen O S; Apell H J; Bamberg E; Busath D D; Koeppe R E; Sigworth F J; Szabo G; Urry D W; Woolley A
Gramicidin channel controversy--the structure in a lipid environment.
Nature structural biology 1999;6(7):609; discussion 611-2.
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1999: Jude A R; Greathouse D V; Koeppe R E; Providence L L; Andersen O S
Modulation of gramicidin channel structure and function by the aliphatic "spacer" residues 10, 12, and 14 between the tryptophans.
Biochemistry 1999;38(3):1030-9.
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1999: Killian J A; Morein S; van der Wel P C; de Planque M R; Greathouse D V; Koeppe R E
Peptide influences on lipids.
Novartis Foundation symposium 1999;225():170-83; discussion 183-7.
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1999: Koeppe R E; Greathouse D V; Providence L L; Shobana S; Andersen O S
Design and characterization of gramicidin channels with side chain or backbone mutations.
Novartis Foundation symposium 1999;225():44-55; discussion 55-61.
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1999: Greathouse D V; Koeppe R E; Providence L L; Shobana S; Andersen O S
Design and characterization of gramicidin channels.
Methods in enzymology 1999;294():525-50.
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1999: Andersen O S; Nielsen C; Maer A M; Lundbaek J A; Goulian M; Koeppe R E
Ion channels as tools to monitor lipid bilayer-membrane protein interactions: gramicidin channels as molecular force transducers.
Methods in enzymology 1999;294():208-24.
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1998: de Planque M R; Greathouse D V; Koeppe R E; Schäfer H; Marsh D; Killian J A
Influence of lipid/peptide hydrophobic mismatch on the thickness of diacylphosphatidylcholine bilayers. A 2H NMR and ESR study using designed transmembrane alpha-helical peptides and gramicidin A.
Biochemistry 1998;37(26):9333-45.
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1997: Morein S; Strandberg E; Killian J A; Persson S; Arvidson G; Koeppe R E; Lindblom G
Influence of membrane-spanning alpha-helical peptides on the phase behavior of the dioleoylphosphatidylcholine/water system.
Biophysical journal 1997;73(6):3078-88.
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1997: Girshman J; Greathouse D V; Koeppe R E; Andersen O S
Gramicidin channels in phospholipid bilayers with unsaturated acyl chains.
Biophysical journal 1997;73(3):1310-9.
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1996: Andersen O S; Saberwal G; Greathouse D V; Koeppe R E
Gramicidin channels--a solvable membrane "protein" folding problem.
Indian journal of biochemistry & biophysics 1996;33(5):331-42.
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1996: Koeppe R E; Vogt T C; Greathouse D V; Killian J A; de Kruijff B
Conformation of the acylation site of palmitoylgramicidin in lipid bilayers of dimyristoylphosphatidylcholine.
Biochemistry 1996;35(11):3641-8.
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1996: Killian J A; Salemink I; de Planque M R; Lindblom G; Koeppe R E; Greathouse D V
Induction of nonbilayer structures in diacylphosphatidylcholine model membranes by transmembrane alpha-helical peptides: importance of hydrophobic mismatch and proposed role of tryptophans.
Biochemistry 1996;35(3):1037-45.
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1996: Koeppe R E; Anderson O S
Engineering the gramicidin channel.
Annual review of biophysics and biomolecular structure 1996;25():231-58.
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1995: Providence L L; Andersen O S; Greathouse D V; Koeppe R E; Bittman R
Gramicidin channel function does not depend on phospholipid chirality.
Biochemistry 1995;34(50):16404-11.
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1995: Koeppe R E; Killian J A; Vogt T C; de Kruijff B; Taylor M J; Mattice G L; Greathouse D V
Palmitoylation-induced conformational changes of specific side chains in the gramicidin transmembrane channel.
Biochemistry 1995;34(29):9299-306.
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1995: Mattice G L; Koeppe R E; Providence L L; Andersen O S
Stabilizing effect of D-alanine2 in gramicidin channels.
Biochemistry 1995;34(20):6827-37.
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1995: Oiki S; Koeppe R E; Andersen O S
Voltage-dependent gating of an asymmetric gramicidin channel.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):2121-5.
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1994: Oiki S; Koeppe R E; Andersen O S
Asymmetric gramicidin channels: heterodimeric channels with a single F6Val1 residue.
Biophysical journal 1994;66(6):1823-32.
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1994: Koeppe R E; Greathouse D V; Jude A; Saberwal G; Providence L L; Andersen O S
Helix sense of gramicidin channels as a "nonlocal" function of the primary sequence.
The Journal of biological chemistry 1994;269(17):12567-76.
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1994: Greathouse D V; Hinton J F; Kim K S; Koeppe R E
Gramicidin A/short-chain phospholipid dispersions: chain length dependence of gramicidin conformation and lipid organization.
Biochemistry 1994;33(14):4291-9.
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1994: Koeppe R E; Killian J A; Greathouse D V
Orientations of the tryptophan 9 and 11 side chains of the gramicidin channel based on deuterium nuclear magnetic resonance spectroscopy.
Biophysical journal 1994;66(1):14-24.
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1993: Durkin J T; Providence L L; Koeppe R E; Andersen O S
Energetics of heterodimer formation among gramicidin analogues with an NH2-terminal addition or deletion. Consequences of missing a residue at the join in the channel.
Journal of molecular biology 1993;231(4):1102-21.
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1992: Killian J A; Taylor M J; Koeppe R E
Orientation of the valine-1 side chain of the gramicidin transmembrane channel and implications for channel functioning. A 2H NMR study.
Biochemistry 1992;31(46):11283-90.
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1992: Williams L P; Narcessian E J; Andersen O S; Waller G R; Taylor M J; Lazenby J P; Hinton J F; Koeppe R E
Molecular and channel-forming characteristics of gramicidin K's: a family of naturally occurring acylated gramicidins.
Biochemistry 1992;31(32):7311-9.
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1992: Oiki S; Koeppe R E; Andersen O S
A dipolar amino acid substitution induces voltage-dependent transitions between two stable conductance states in gramicidin channels.
Biophysical journal 1992;62(1):28-30.
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1992: Becker M D; Koeppe R E; Andersen O S
Amino acid substitutions and ion channel function. Model-dependent conclusions.
Biophysical journal 1992;62(1):25-7.
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1992: Durkin J T; Providence L L; Koeppe R E; Andersen O S
Formation of non-beta 6.3-helical gramicidin channels between sequence-substituted gramicidin analogues.
Biophysical journal 1992;62(1):145-57; discussion 157-9.
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1992: Koeppe R E; Providence L L; Greathouse D V; Heitz F; Trudelle Y; Purdie N; Andersen O S
On the helix sense of gramicidin A single channels.
Proteins 1992;12(1):49-62.
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1992: Cifu A S; Koeppe R E; Andersen O S
On the supramolecular organization of gramicidin channels. The elementary conducting unit is a dimer.
Biophysical journal 1992;61(1):189-203.
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1991: Becker M D; Greathouse D V; Koeppe R E; Andersen O S
Amino acid sequence modulation of gramicidin channel function: effects of tryptophan-to-phenylalanine substitutions on the single-channel conductance and duration.
Biochemistry 1991;30(36):8830-9.
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1990: Sawyer D B; Williams L P; Whaley W L; Koeppe R E; Andersen O S
Gramicidins A, B, and C form structurally equivalent ion channels.
Biophysical journal 1990;58(5):1207-12.
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1990: O'Connell A M; Koeppe R E; Andersen O S
Kinetics of gramicidin channel formation in lipid bilayers: transmembrane monomer association.
Science (New York, N.Y.) 1990;250(4985):1256-9.
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1990: Sawyer D B; Koeppe R E; Andersen O S
Gramicidin single-channel properties show no solvent-history dependence.
Biophysical journal 1990;57(3):515-23.
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1990: Koeppe R E; Mazet J L; Andersen O S
Distinction between dipolar and inductive effects in modulating the conductance of gramicidin channels.
Biochemistry 1990;29(2):512-20.
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1990: Durkin J T; Koeppe R E; Andersen O S
Energetics of gramicidin hybrid channel formation as a test for structural equivalence. Side-chain substitutions in the native sequence.
Journal of molecular biology 1990;211(1):221-34.
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1989: Sawyer D B; Koeppe R E; Andersen O S
Induction of conductance heterogeneity in gramicidin channels.
Biochemistry 1989;28(16):6571-83.
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1988: Hinton J F; Fernandez J Q; Shungu D C; Whaley W L; Koeppe R E; Millett F S
TI-205 nuclear magnetic resonance determination of the thermodynamic parameters for the binding of monovalent cations to gramicidins A and C.
Biophysical journal 1988;54(3):527-33.
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1986: Shungu D C; Hinton J F; Koeppe R E; Millett F S
Investigation of the interaction between thallous ions and gramicidin A in dimyristoylphosphatidylcholine vesicles: a thallium-205 NMR equilibrium study.
Biochemistry 1986;25(20):6103-8.
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1986: Hinton J F; Whaley W L; Shungu D; Koeppe R E; Millett F S
Equilibrium binding constants for the group I metal cations with gramicidin-A determined by competition studies and T1+-205 nuclear magnetic resonance spectroscopy.
Biophysical journal 1986;50(3):539-44.
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1986: Hinton J F; Koeppe R E; Shungu D; Whaley W L; Paczkowski J A; Millett F S
Equilibrium binding constants for Tl+ with gramicidins A, B and C in a lysophosphatidylcholine environment determined by 205Tl nuclear magnetic resonance spectroscopy.
Biophysical journal 1986;49(2):571-7.
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1985: Koeppe R E; Paczkowski J A; Whaley W L
Gramicidin K, a new linear channel-forming gramicidin from Bacillus brevis.
Biochemistry 1985;24(12):2822-6.
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1984: Mazet J L; Andersen O S; Koeppe R E
Single-channel studies on linear gramicidins with altered amino acid sequences. A comparison of phenylalanine, tryptophane, and tyrosine substitutions at positions 1 and 11.
Biophysical journal 1984;45(1):263-76.
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