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Chong-Lek Koh

Research Profile

Geographic Areas

Malaysia

Physiology

Quorum Sensing

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Chemicals & Drugs

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Disorders

Genes & Molecular Sequences

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Publications

TOP 3
Chong-Lek Koh; Thiba Krishnan; Choon-Kook Sam; Li Ying Tan; Wai-Fong Yin; Yee Meng Chong; Kok-Gan Chan
Plant-derived natural products as sources of anti-quorum sensing compounds.
Kar-Wai Hong; Chong-Lek Koh; Choon-Kook Sam; Wai-Fong Yin; Kok-Gan Chan
Whole-genome sequence of N-acylhomoserine lactone-synthesizing and -degrading Acinetobacter sp. strain GG2.
Kar-Wai Hong; Chong-Lek Koh; Choon-Kook Sam; Wai-Fong Yin; Kok-Gan Chan
Complete genome sequence of Burkholderia sp. Strain GG4, a betaproteobacterium that reduces 3-oxo-N-acylhomoserine lactones and produces different N-acylhomoserine lactones.

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All Publications

2013: Chong-Lek Koh; Thiba Krishnan; Choon-Kook Sam; Li Ying Tan; Wai-Fong Yin; Yee Meng Chong; Kok-Gan Chan
Plant-derived natural products as sources of anti-quorum sensing compounds.
Sensors (Basel, Switzerland) 2013;13(5):6217-28.
2012: Kar-Wai Hong; Chong-Lek Koh; Choon-Kook Sam; Wai-Fong Yin; Kok-Gan Chan
Whole-genome sequence of N-acylhomoserine lactone-synthesizing and -degrading Acinetobacter sp. strain GG2.
Journal of bacteriology 2012;194(22):6318.
2012: Kar-Wai Hong; Chong-Lek Koh; Choon-Kook Sam; Wai-Fong Yin; Kok-Gan Chan
Complete genome sequence of Burkholderia sp. Strain GG4, a betaproteobacterium that reduces 3-oxo-N-acylhomoserine lactones and produces different N-acylhomoserine lactones.
Journal of bacteriology 2012;194(22):6317.
2012: Robert Sautter; Lisa Schneper; Tina Wassermann; Søren Molin; Dennis E Ohman; Damaris Ramos; Oana Ciofu; Caroline A Devries; Morten Hentzer; Arne Heydorn; Niels Høiby; Arsalan Kharazmi; Chong-Lek Koh; Kalai Mathee
A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production.
Gene 2012;498(2):242-53.
2012: Cheng-Siang Wong; Wai-Fong Yin; Yeun-Mun Choo; Chong-Lek Koh; Choon-Kook Sam; Kok-Gan Chan
Coexistence of quorum-quenching and quorum-sensing in tropical marine Pseudomonas aeruginosa strain MW3A.
World journal of microbiology & biotechnology 2012;28(2):453-61.
2012: Chien-Yi Chang; Chong-Lek Koh; Choon-Kook Sam; Wai Fong Yin; Xin-Yue Chan; Kok Gan Chan
Unusual long-chain N-acyl homoserine lactone production by and presence of quorum quenching activity in bacterial isolates from diseased tilapia fish.
PloS one 2012;7(8):e44034.
2012: Wai-Fong Yin; Xin-Yue Chan; Shenyang Chin; Chong-Lek Koh; Kathiravan Purmal; Choon-Kook Sam; Kok-Gan Chan
N-acyl homoserine lactone production by Klebsiella pneumoniae isolated from human tongue surface.
Sensors (Basel, Switzerland) 2012;12(3):3472-83.
2012: Teik-Min Chong; Yeun-Mun Choo; Chong-Lek Koh; Choon-Kook Sam; Wai-Fong Yin; Kok-Gan Chan
Characterization of quorum sensing and quorum quenching soil bacteria isolated from Malaysian tropical montane forest.
Sensors (Basel, Switzerland) 2012;12(4):4846-59.
2012: Kar-Wai Hong; Chong-Lek Koh; Choon-Kook Sam; Wai-Fong Yin; Kok-Gan Chan
Quorum quenching revisited--from signal decays to signalling confusion.
Sensors (Basel, Switzerland) 2012;12(4):4661-96.
2012: Wai-Fong Yin; Chong-Lek Koh; Choon-Kook Sam; Hun-Jiat Tung; Kok-Gan Chan
Quorum quenching Bacillus sonorensis isolated from soya sauce fermentation brine.
Sensors (Basel, Switzerland) 2012;12(4):4065-73.
2012: Cheng-Siang Wong; Wai-Fong Yin; Chong-Lek Koh; Choon-Kook Sam; Kok-Gan Chan
Characterization of wetland quorum quenching Pseudomonas aeruginosa strain 2SW8 and its 2-heptyl-3-hydroxy-4-quinolone production.
The new microbiologica 2012;35(1):43-51.
2011: Yee Meng Chong; A Hamid A Hadi; Chia Yong Ho; Chong-Lek Koh; Mohd Mustafa; Putri Narrima; Wai Fong Yin; David R Appleton; Khalijah Awang; Kok-Gan Chan
Malabaricone C from Myristica cinnamomea exhibits anti-quorum sensing activity.
Journal of natural products 2011;74(10):2261-4.
2011: Kok-Gan Chan; Steve Atkinson; Kalai Mathee; Choon-Kook Sam; Siri Ram Chhabra; Miguel Cámara; Chong-Lek Koh; Paul Williams
Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia.
BMC microbiology 2011;11():51.
2010: Abdullah Maha; Gin Gin Gan; Chong-Lek Koh
Phenotype and TCR-gamma gene rearrangements in a Malaysian cohort of T-cell leukaemia/lymphoma cases.
Hematology (Amsterdam, Netherlands) 2010;15(6):382-90.
2010: Kok-Gan Chan; Cheng-Siang Wong; Wai-Fong Yin; Choon-Kook Sam; Chong-Lek Koh
Rapid degradation of N-3-oxo-acylhomoserine lactones by a Bacillus cereus isolate from Malaysian rainforest soil.
Antonie van Leeuwenhoek 2010;98(3):299-305.
2009: Kok-Gan Chan; Wai-Fong Yin; Choon-Kook Sam; Chong-Lek Koh
A novel medium for the isolation of N-acylhomoserine lactone-degrading bacteria.
Journal of industrial microbiology & biotechnology 2009;36(2):247-51.
2005: Kok-Fai Kong; Suriya Ravi Jayawardena; Shalaka Dayaram Indulkar; Aimee Del Puerto; Chong-Lek Koh; Niels Høiby; Kalai Mathee
Pseudomonas aeruginosa AmpR is a global transcriptional factor that regulates expression of AmpC and PoxB beta-lactamases, proteases, quorum sensing, and other virulence factors.
Antimicrobial agents and chemotherapy 2005;49(11):4567-75.
2004: Yee Peng Chan; Chong-Lek Koh; Sai Kit Lam; Lin-Fa Wang
Mapping of domains responsible for nucleocapsid protein-phosphoprotein interaction of Henipaviruses.
The Journal of general virology 2004;85(Pt 6):1675-84.
2004: Pei-Chieng Cha; Ryo Yamada; Akihiro Sekine; Yusuke Nakamura; Chong-Lek Koh
Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations.
Journal of human genetics 2004;49(10):558-72.
2002: Kaw Bing Chua; Chong-Lek Koh; Poh Sim Hooi; Kong Fatt Wee; Jenn Hui Khong; Beng Hooi Chua; Yee Peng Chan; Mou Eng Lim; Sai Kit Lam
Isolation of Nipah virus from Malaysian Island flying-foxes.
Microbes and infection / Institut Pasteur 2002;4(2):145-51.
2001: Yee Peng Chan; Kaw Bing Chua; Chong-Lek Koh; Mou Eng Lim; Sai Kit Lam
Complete nucleotide sequences of Nipah virus isolates from Malaysia.
The Journal of general virology 2001;82(Pt 9):2151-5.
1998: Mun-Yik Fong; Chong-Lek Koh; Sai Kit Lam
Molecular epidemiology of Malaysian dengue 2 viruses isolated over twenty-five years (1968-1993).
Research in virology 1998;149(6):457-64.
1997: Chong-Lek Koh; Mou Eng Lim; H S Ng; Choon-Kook Sam
D1S80 (pMCT118) allele frequencies in a Malay population sample from Malaysia.
International journal of legal medicine 1997;110(1):39-40.
1994: Chong-Lek Koh; D G Benjamin
HLA-DQ alpha genotype and allele frequencies in Malays, Chinese, and Indians in the Malaysian population.
Human heredity 1994;44(3):150-5.
1994: Kwai-Lin Thong; Y M Cheong; Savithri D Puthucheary; Chong-Lek Koh; Tikki Pang
Epidemiologic analysis of sporadic Salmonella typhi isolates and those from outbreaks by pulsed-field gel electrophoresis.
Journal of clinical microbiology 1994;32(5):1135-41.
1993: A Verdugo-Rodriguez; L H Gam; Shamala Devi; Chong-Lek Koh; Savithri D Puthucheary; E Calva; Tikki Pang
Detection of antibodies against Salmonella typhi outer membrane protein (OMP) preparation in typhoid fever patients.
Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand 1993;11(1):45-52.
1993: W N Yusof; M Nagaratnam; Chong-Lek Koh; Savithri D Puthucheary; Tikki Pang
Release of prostaglandin E2 by human mononuclear cells exposed to heat-killed Salmonella typhi.
Microbiology and immunology 1993;37(8):667-70.
1992: Tikki Pang; M Altwegg; G Martinetti; Chong-Lek Koh; Savithri D Puthucheary
Genetic variation among Malaysian isolates of Salmonella typhi as detected by ribosomal RNA gene restriction patterns.
Microbiology and immunology 1992;36(5):539-43.
1991: Maude E Phipps; Tikki Pang; Chong-Lek Koh; Savithri D Puthucheary
Plasmid incidence rate and conjugative chloramphenicol and tetracycline resistance plasmids in Malaysian isolates of Salmonella typhi.
Microbiology and immunology 1991;35(2):157-61.
1990: S Samuel; Chong-Lek Koh; Tikki Pang; S K Lam
Nucleotide and encoded amino acid sequences of the membrane protein precursor and the membrane protein genes of three dengue-2 viruses isolated in Malaysia from patients with dengue haemorrhagic fever, dengue shock syndrome or dengue fever.
Nucleic acids research 1990;18(7):1905.
1990: S Samuel; Chong-Lek Koh; Tikki Pang; S K Lam
Nucleotide and encoded amino acid sequences of the capsid protein gene of three dengue-2 viruses isolated in Malaysia from patients with dengue haemorrhagic fever, dengue shock syndrome or dengue fever.
Nucleic acids research 1990;18(7):1904.
1990: M Y Fong; Chong-Lek Koh; S Samuel; Tikki Pang; S K Lam
Nucleotide sequences of the nonstructural protein NS1 gene of three dengue-2 viruses, M1, M2 and M3, isolated in Malaysia from patients with dengue haemorrhagic fever, dengue shock syndrome and dengue fever, respectively.
Nucleic acids research 1990;18(6):1642.
1989: S Samuel; Chong-Lek Koh; J Blok; Tikki Pang; S K Lam
Nucleotide sequence of the envelope protein gene of a Malaysian dengue-2 virus isolated from a patient with dengue shock syndrome.
Nucleic acids research 1989;17(21):8888.
1989: S Samuel; Chong-Lek Koh; J Blok; Tikki Pang; S K Lam
Nucleotide sequence of the envelope protein gene of a Malaysian dengue-2 virus isolated from a patient with dengue fever.
Nucleic acids research 1989;17(21):8887.
1989: S Samuel; Chong-Lek Koh; J Blok; Tikki Pang; S K Lam
Nucleotide sequence of the envelope protein gene of a Malaysian dengue-2 virus isolated from a patient with dengue haemorrhagic fever.
Nucleic acids research 1989;17(21):8875.
1983: Chong-Lek Koh; M E Lim; Y H Wong
Conjugal transfer of multiple antibiotic resistance from hospital isolates of Klebsiella to Escherichia coli.
The Southeast Asian journal of tropical medicine and public health 1983;14(3):336-40.