Isaac Kohane

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Oligonucleotide Array Sequence Analysis

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Davis Adam R; Kohane Isaac S
Expression differences by continent of origin point to the immortalization process.
Weber Griffin M; Murphy Shawn N; McMurry Andrew J; Macfadden Douglas; Nigrin Daniel J; Churchill Susanne; Kohane Isaac S
The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories.
Roach Kenneth L; King Kevin R; Uygun Korkut; Hand Steven C; Kohane Isaac S; Yarmush Martin L; Toner Mehmet
High-throughput single cell arrays as a novel tool in biopreservation.

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All Publications

2009: Davis Adam R; Kohane Isaac S
Expression differences by continent of origin point to the immortalization process.
Human molecular genetics 2009;18(20):3864-75.
2009: Weber Griffin M; Murphy Shawn N; McMurry Andrew J; Macfadden Douglas; Nigrin Daniel J; Churchill Susanne; Kohane Isaac S
The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories.
Journal of the American Medical Informatics Association : JAMIA 2009;16(5):624-30.
2009: Roach Kenneth L; King Kevin R; Uygun Korkut; Hand Steven C; Kohane Isaac S; Yarmush Martin L; Toner Mehmet
High-throughput single cell arrays as a novel tool in biopreservation.
Cryobiology 2009;58(3):315-21.
2009: Himes Blanca E; Dai Yi; Kohane Isaac S; Weiss Scott T; Ramoni Marco F
Prediction of chronic obstructive pulmonary disease (COPD) in asthma patients using electronic medical records.
Journal of the American Medical Informatics Association : JAMIA 2009;16(3):371-9.
2009: Tian Ze; An Ning; Zhou Bin; Xiao Peigen; Kohane Isaac S; Wu Erxi
Cytotoxic diarylheptanoid induces cell cycle arrest and apoptosis via increasing ATF3 and stabilizing p53 in SH-SY5Y cells.
Cancer chemotherapy and pharmacology 2009;63(6):1131-9.
2009: Eran Alal; Graham Kaitlin R; Vatalaro Kayla; McCarthy Jillian; Collins Christin; Peters Heather; Brewster Stephanie J; Hanson Ellen; Hundley Rachel; Rappaport Leonard; Holm Ingrid A; Kohane Isaac S; Kunkel Louis M
Comment on "Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients".
The Journal of clinical investigation 2009;119(4):679-80; author reply 680-1.
2009: Mandl Kenneth D; Kohane Isaac S
No small change for the health information economy.
The New England journal of medicine 2009;360(13):1278-81.
2009: Wall D P; Esteban F J; Deluca T F; Huyck M; Monaghan T; Velez de Mendizabal N; Goñí J; Kohane I S
Comparative analysis of neurological disorders focuses genome-wide search for autism genes.
Genomics 2009;93(2):120-9.
2009: Kohane I
Ten thousand views of bioinformatics: a bibliome perspective.
Yearbook of medical informatics 2009;():113-6.
2009: Reis Ben Y; Kohane Isaac S; Mandl Kenneth D
Longitudinal histories as predictors of future diagnoses of domestic abuse: modelling study.
BMJ (Clinical research ed.) 2009;339():b3677.
2009: Liu Hongye; Kohane Isaac S;
Tissue and process specific microRNA-mRNA co-expression in mammalian development and malignancy.
PloS one 2009;4(5):e5436.
2009: Tian Ze; Palmer Nathan; Schmid Patrick; Yao Hui; Galdzicki Michal; Berger Bonnie; Wu Erxi; Kohane Isaac S
A practical platform for blood biomarker study by using global gene expression profiling of peripheral whole blood.
PloS one 2009;4(4):e5157.
2008: Mandl Kenneth D; Kohane Isaac S
Tectonic shifts in the health information economy.
The New England journal of medicine 2008;358(16):1732-7.
2008: Tian Ze; Shen Jie; Moseman Annie P; Yang Quanli; Yang Junshan; Xiao Peigen; Wu Erxi; Kohane Isaac S
Dulxanthone A induces cell cycle arrest and apoptosis via up-regulation of p53 through mitochondrial pathway in HepG2 cells.
International journal of cancer. Journal international du cancer 2008;122(1):31-8.
2008: Wu Erxi; Palmer Nathan; Tian Ze; Moseman Annie P; Galdzicki Michal; Wang Xuetao; Berger Bonnie; Zhang Hongbing; Kohane Isaac S
Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells.
PloS one 2008;3(11):e3794.
2008: Himes Blanca E; Kohane Isaac S; Ramoni Marco F; Weiss Scott T
Characterization of patients who suffer asthma exacerbations using data extracted from electronic medical records.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2008;():308-12.
2008: Cassa Christopher A; Schmidt Brian; Kohane Isaac S; Mandl Kenneth D
My sister's keeper?: genomic research and the identifiability of siblings.
BMC medical genomics 2008;1():32.
2008: Naxerova Kamila; Bult Carol J; Peaston Anne; Fancher Karen; Knowles Barbara B; Kasif Simon; Kohane Isaac S
Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers.
Genome biology 2008;9(7):R108.
2008: Dinov Ivo D; Rubin Daniel; Lorensen William; Dugan Jonathan; Ma Jeff; Murphy Shawn; Kirschner Beth; Bug William; Sherman Michael; Floratos Aris; Kennedy David; Jagadish H V; Schmidt Jeanette; Athey Brian; Califano Andrea; Musen Mark; Altman Russ; Kikinis Ron; Kohane Isaac; Delp Scott; Parker D Stott; Toga Arthur W
iTools: a framework for classification, categorization and integration of computational biology resources.
PloS one 2008;3(5):e2265.
2007: Eisenberg Iris; Eran Alal; Nishino Ichizo; Moggio Maurizio; Lamperti Costanza; Amato Anthony A; Lidov Hart G; Kang Peter B; North Kathryn N; Mitrani-Rosenbaum Stella; Flanigan Kevin M; Neely Lori A; Whitney Duncan; Beggs Alan H; Kohane Isaac S; Kunkel Louis M
Distinctive patterns of microRNA expression in primary muscular disorders.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(43):17016-21.
2007: Ramlawi Basel; Otu Hasan; Rudolph James L; Mieno Shigetoshi; Kohane Isaac S; Can Handan; Libermann Towia A; Marcantonio Edward R; Bianchi Cesario; Sellke Frank W
Genomic expression pathways associated with brain injury after cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 2007;134(4):996-1005.
2007: Drake Thomas A; Braun Jonathan; Marchevsky Alberto; Kohane Isaac S; Fletcher Christopher; Chueh Henry; Beckwith Bruce; Berkowicz David; Kuo Frank; Zeng Qing T; Balis Ulysses; Holzbach Ana; McMurry Andrew; Gee Connie E; McDonald Clement J; Schadow Gunther; Davis Mary; Hattab Eyas M; Blevins Lonnie; Hook John; Becich Michael; Crowley Rebecca S; Taube Sheila E; Berman Jules;
A system for sharing routine surgical pathology specimens across institutions: the Shared Pathology Informatics Network.
Human pathology 2007;38(8):1212-25.
2007: McMurry Andrew J; Gilbert Clint A; Reis Ben Y; Chueh Henry C; Kohane Isaac S; Mandl Kenneth D
A self-scaling, distributed information architecture for public health, research, and clinical care.
Journal of the American Medical Informatics Association : JAMIA 2007;14(4):527-33.
2007: Reis Ben Y; Kohane Isaac S; Mandl Kenneth D
An epidemiological network model for disease outbreak detection.
PLoS medicine 2007;4(6):e210.
2007: Liu Manway; Liberzon Arthur; Kong Sek Won; Lai Weil R; Park Peter J; Kohane Isaac S; Kasif Simon
Network-based analysis of affected biological processes in type 2 diabetes models.
PLoS genetics 2007;3(6):e96.
2007: Turchin Alexander; Kolatkar Nikheel S; Pendergrass Merri L; Kohane Isaac S
Computational analysis of non-adherence and non-attendance using the text of narrative physician notes in the electronic medical record.
Medical informatics and the Internet in medicine 2007;32(2):93-102.
2007: Kohane Isaac S; Mandl Kenneth D; Taylor Patrick L; Holm Ingrid A; Nigrin Daniel J; Kunkel Louis M
Medicine. Reestablishing the researcher-patient compact.
Science (New York, N.Y.) 2007;316(5826):836-7.
2007: Inaoka Hidenori; Fukuoka Yutaka; Kohane Isaac S
Evidence of spatially bound gene regulation in Mus musculus: decreased gene expression proximal to microRNA genomic location.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5020-5.
2007: Murphy Shawn N; Mendis Michael; Hackett Kristel; Kuttan Rajesh; Pan Wensong; Phillips Lori C; Gainer Vivian; Berkowicz David; Glaser John P; Kohane Isaac; Chueh Henry C
Architecture of the open-source clinical research chart from Informatics for Integrating Biology and the Bedside.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2007;():548-52.
2007: Cohen Jennifer; Van Marter Linda J; Sun Yao; Allred Elizabeth; Leviton Alan; Kohane Isaac S
Perturbation of gene expression of the chromatin remodeling pathway in premature newborns at risk for bronchopulmonary dysplasia.
Genome biology 2007;8(10):R210.
2007: Brownstein John S; Sordo Margarita; Kohane Isaac S; Mandl Kenneth D
The tell-tale heart: population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction.
PloS one 2007;2(9):e840.
2007: Loscalzo Joseph; Kohane Isaac; Barabasi Albert-Laszlo
Human disease classification in the postgenomic era: a complex systems approach to human pathobiology.
Molecular systems biology 2007;3():124.
2007: Patel Ashokkumar A; Gupta Dilipkumar; Seligson David; Hattab Eyas M; Balis Ulysses J; Ulbright Thomas M; Kohane Isaac S; Berman Jules J; Gilbertson John R; Dry Sarah; Schirripa Osvaldo; Yu Hong; Becich Michael J; Parwani Anil V;
Availability and quality of paraffin blocks identified in pathology archives: a multi-institutional study by the Shared Pathology Informatics Network (SPIN).
BMC cancer 2007;7():37.
2007: Allocco Dominic J; Song Qing; Gibbons Gary H; Ramoni Marco F; Kohane Isaac S
Geography and genography: prediction of continental origin using randomly selected single nucleotide polymorphisms.
BMC genomics 2007;8():68.
2006: Chu Eric K; Cheng Jason; Foley John S; Mecham Brigham H; Owen Caroline A; Haley Kathleen J; Mariani Thomas J; Kohane Isaac S; Tschumperlin Daniel J; Drazen Jeffrey M
Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells.
American journal of respiratory cell and molecular biology 2006;35(6):628-38.
2006: Frank Natasha Y; Kho Alvin T; Schatton Tobias; Murphy George F; Molloy Michael J; Zhan Qian; Ramoni Marco F; Frank Markus H; Kohane Isaac S; Gussoni Emanuela
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin.
The Journal of cell biology 2006;175(1):99-110.
2006: Carter Scott L; Eklund Aron C; Kohane Isaac S; Harris Lyndsay N; Szallasi Zoltan
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.
Nature genetics 2006;38(9):1043-8.
2006: Gazda Hanna T; Kho Alvin T; Sanoudou Despina; Zaucha Jan M; Kohane Isaac S; Sieff Colin A; Beggs Alan H
Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia.
Stem cells (Dayton, Ohio) 2006;24(9):2034-44.
2006: Hung Kenneth E; Kho Alvin T; Sarracino David; Richard Larissa Georgeon; Krastins Bryan; Forrester Sara; Haab Brian B; Kohane Isaac S; Kucherlapati Raju
Mass spectrometry-based study of the plasma proteome in a mouse intestinal tumor model.
Journal of proteome research 2006;5(8):1866-78.
2006: Kohane Isaac S; Masys Daniel R; Altman Russ B
The incidentalome: a threat to genomic medicine.
JAMA : the journal of the American Medical Association 2006;296(2):212-5.
2006: Liu Hongye; Kho Alvin T; Kohane Isaac S; Sun Yao
Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development.
PLoS medicine 2006;3(7):e232.
2006: Turchin Alexander; Guo Christine Z; Adler Gail K; Ricchiuti Vincent; Kohane Isaac S; Williams Gordon H
Effect of acute aldosterone administration on gene expression profile in the heart.
Endocrinology 2006;147(7):3183-9.
2006: Sebastiani Paola; Mandl Kenneth D; Szolovits Peter; Kohane Isaac S; Ramoni Marco F
A Bayesian dynamic model for influenza surveillance.
Statistics in medicine 2006;25(11):1803-16; discussion 1817-25.
2006: Marinescu Voichita D; Kohane Isaac S; Kim Tae-Kyung; Harmin David A; Greenberg Michael E; Riva Alberto
START: an automated tool for serial analysis of chromatin occupancy data.
Bioinformatics (Oxford, England) 2006;22(8):999-1001.
2006: Butte Atul J; Kohane Isaac S
Creation and implications of a phenome-genome network.
Nature biotechnology 2006;24(1):55-62.
2006: Simons William W; Halamka John D; Kohane Isaac S; Nigrin Daniel; Finstein Nathan; Mandl Kenneth D
Integration of the personally controlled electronic medical record into regional inter-regional data exchanges: a national demonstration.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2006;():1099.
2006: Murphy Shawn N; Mendis Michael E; Berkowitz David A; Kohane Isaac; Chueh Henry C
Integration of clinical and genetic data in the i2b2 architecture.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2006;():1040.
2006: Hackett Kristel L; Kohane Isaac S; Chueh Henry C; Murphy Shawn N
Mapping tool for maintaining vocabulary relationships.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2006;():939.
2006: Brownstein John S; Cassa Christopher A; Kohane Isaac S; Mandl Kenneth D
An unsupervised classification method for inferring original case locations from low-resolution disease maps.
International journal of health geographics 2006;5():56.
2006: Adida Ben; Kohane Isaac S
GenePING: secure, scalable management of personal genomic data.
BMC genomics 2006;7():93.
2006: Kho Alvin T; Kang Peter B; Kohane Isaac S; Kunkel Louis M
Transcriptome-scale similarities between mouse and human skeletal muscles with normal and myopathic phenotypes.
BMC musculoskeletal disorders 2006;7():23.
2006: Inaoka Hidenori; Fukuoka Yutaka; Kohane Isaac S
Lower expression of genes near microRNA in C. elegans germline.
BMC bioinformatics 2006;7():112.
2005: Schachter Asher D; Ichimura Takaharu; Kohane Isaac S
Chromosomes 18 and X are quantitative trait loci for nephrotic-range proteinuria in rats.
Pediatric nephrology (Berlin, Germany) 2005;20(12):1717-23.
2005: Kohane Isaac S; Altman Russ B
Health-information altruists--a potentially critical resource.
The New England journal of medicine 2005;353(19):2074-7.
2005: Haslett Judith N; Kang Peter B; Han Mei; Kho Alvin T; Sanoudou Despina; Volinski Jay M; Beggs Alan H; Kohane Isaac S; Kunkel Louis M
The influence of muscle type and dystrophin deficiency on murine expression profiles.
Mammalian genome : official journal of the International Mammalian Genome Society 2005;16(10):739-48.
2005: Tian Lu; Greenberg Steven A; Kong Sek Won; Altschuler Josiah; Kohane Isaac S; Park Peter J
Discovering statistically significant pathways in expression profiling studies.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13544-9.
2005: Turchin Alexander; Kohane Isaac S; Pendergrass Merri L
Identification of patients with diabetes from the text of physician notes in the electronic medical record.
Diabetes care 2005;28(7):1794-5.
2005: Kong Sek Won; Hwang Kyu-Baek; Kim Richard D; Zhang Byoung-Tak; Greenberg Steven A; Kohane Isaac S; Park Peter J
CrossChip: a system supporting comparative analysis of different generations of Affymetrix arrays.
Bioinformatics (Oxford, England) 2005;21(9):2116-7.
2005: Sax Ulrich; Kohane Isaac; Mandl Kenneth D
Wireless technology infrastructures for authentication of patients: PKI that rings.
Journal of the American Medical Informatics Association : JAMIA 2005;12(3):263-8.
2005: Porter Stephen C; Kohane Isaac S; Goldmann Donald A
Parents as partners in obtaining the medication history.
Journal of the American Medical Informatics Association : JAMIA 2005;12(3):299-305.
2005: Marinescu Voichita D; Kohane Isaac S; Riva Alberto
The MAPPER database: a multi-genome catalog of putative transcription factor binding sites.
Nucleic acids research 2005;33(Database issue):D91-7.
2005: Simons William W; Mandl Kenneth D; Kohane Isaac S
The PING personally controlled electronic medical record system: technical architecture.
Journal of the American Medical Informatics Association : JAMIA 2005;12(1):47-54.
2005: Brownstein John S; Cassa Christopher A; Kohane Isaac S; Mandl Kenneth D
Reverse geocoding: concerns about patient confidentiality in the display of geospatial health data.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2005;():905.
2005: Turchin Alexander; Pendergrass Merri L; Kohane Isaac S
DITTO - a tool for identification of patient cohorts from the text of physician notes in the electronic medical record.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2005;():744-8.
2005: Lee Soohyun; Kohane Isaac; Kasif Simon
Genes involved in complex adaptive processes tend to have highly conserved upstream regions in mammalian genomes.
BMC genomics 2005;6():168.
2005: Wolfe Cecily J; Kohane Isaac S; Butte Atul J
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks.
BMC bioinformatics 2005;6():227.
2005: Carter Scott L; Eklund Aron C; Mecham Brigham H; Kohane Isaac S; Szallasi Zoltan
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in cancer-associated gene expression measurements.
BMC bioinformatics 2005;6():107.
2005: Marinescu Voichita D; Kohane Isaac S; Riva Alberto
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes.
BMC bioinformatics 2005;6():79.
2004: Adam Rosalyn M; Eaton Samuel H; Estrada Carlos; Nimgaonkar Ashish; Shih Shu-Ching; Smith Lois E H; Kohane Isaac S; Bägli Darius; Freeman Michael R
Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells.
Physiological genomics 2004;20(1):36-44.
2004: Porter Stephen C; Cai Zhaohui; Gribbons William; Goldmann Donald A; Kohane Isaac S
The asthma kiosk: a patient-centered technology for collaborative decision support in the emergency department.
Journal of the American Medical Informatics Association : JAMIA 2004;11(6):458-67.
2004: Voisine Pierre; Ruel Marc; Khan Tanveer A; Bianchi Cesario; Xu Shu-Hua; Kohane Isaac; Libermann Towia A; Otu Hasan; Saltiel Alan R; Sellke Frank W
Differences in gene expression profiles of diabetic and nondiabetic patients undergoing cardiopulmonary bypass and cardioplegic arrest.
Circulation 2004;110(11 Suppl 1):II280-6.
2004: Cai Zhaohui; Tsung Eric F; Marinescu Voichita D; Ramoni Marco F; Riva Alberto; Kohane Isaac S
Bayesian approach to discovering pathogenic SNPs in conserved protein domains.
Human mutation 2004;24(2):178-84.
2004: Mecham Brigham H; Wetmore Daniel Z; Szallasi Zoltan; Sadovsky Yoel; Kohane Isaac; Mariani Thomas J
Increased measurement accuracy for sequence-verified microarray probes.
Physiological genomics 2004;18(3):308-15.
2004: Lader Alan S; Ramoni Marco F; Zetter Bruce R; Kohane Isaac S; Kwiatkowski David J
Identification of a transcriptional profile associated with in vitro invasion in non-small cell lung cancer cell lines.
Cancer biology & therapy 2004;3(7):624-31.
2004: Friedman Charles P; Altman Russ B; Kohane Isaac S; McCormick Kathleen A; Miller Perry L; Ozbolt Judy G; Shortliffe Edward H; Stormo Gary D; Szczepaniak M Cleat; Tuck David; Williamson Jeffrey;
Training the next generation of informaticians: the impact of "BISTI" and bioinformatics--a report from the American College of Medical Informatics.
Journal of the American Medical Informatics Association : JAMIA 2004;11(3):167-72.
2004: Sanoudou Despina; Frieden Leslie A; Haslett Judith N; Kho Alvin T; Greenberg Steven A; Kohane Isaac S; Kunkel Louis M; Beggs Alan H
Molecular classification of nemaline myopathies: "nontyping" specimens exhibit unique patterns of gene expression.
Neurobiology of disease 2004;15(3):590-600.
2004: Kho Alvin T; Zhao Qing; Cai Zhaohui; Butte Atul J; Kim John Y H; Pomeroy Scott L; Rowitch David H; Kohane Isaac S
Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers.
Genes & development 2004;18(6):629-40.
2004: Riva Alberto; Kohane Isaac S
A SNP-centric database for the investigation of the human genome.
BMC bioinformatics 2004;5():33.
2004: Allocco Dominic J; Kohane Isaac S; Butte Atul J
Quantifying the relationship between co-expression, co-regulation and gene function.
BMC bioinformatics 2004;5():18.
2004: Nimgaonkar Ashish; Karnad Dilip R; Sudarshan S; Ohno-Machado Lucila; Kohane Isaac
Prediction of mortality in an Indian intensive care unit. Comparison between APACHE II and artificial neural networks.
Intensive care medicine 2004;30(2):248-53.
2004: Tomczak Kinga K; Marinescu Voichita D; Ramoni Marco F; Sanoudou Despina; Montanaro Federica; Han Mei; Kunkel Louis M; Kohane Isaac S; Beggs Alan H
Expression profiling and identification of novel genes involved in myogenic differentiation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(2):403-5.
2004: Fukuoka Yutaka; Inaoka Hidenori; Kohane Isaac S
Inter-species differences of co-expression of neighboring genes in eukaryotic genomes.
BMC genomics 2004;5(1):4.
2004: Alterovitz Gil; Aivado Manuel; Spentzos Dimitrios; Libermann Towia A; Ramoni Marco; Kohane Isaac S
Analysis and robot pipelined automation for SELDI-TOF mass spectrometry.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2004;4():3068-71.
2004: Namini Ahmad H; Berkowicz David A; Kohane Isaac S; Chueh Henry
A submission model for use in the indexing, searching, and retrieval of distributed pathology case and tissue specimens.
Studies in health technology and informatics 2004;107(Pt 2):1264-7.
2004: Mecham Brigham H; Klus Gregory T; Strovel Jeffrey; Augustus Meena; Byrne David; Bozso Peter; Wetmore Daniel Z; Mariani Thomas J; Kohane Isaac S; Szallasi Zoltan
Sequence-matched probes produce increased cross-platform consistency and more reproducible biological results in microarray-based gene expression measurements.
Nucleic acids research 2004;32(9):e74.
2003: Ruel Marc; Bianchi Cesario; Khan Tanveer A; Xu Shu; Liddicoat John R; Voisine Pierre; Araujo Eugenio; Lyon Helen; Kohane Isaac S; Libermann Towia A; Sellke Frank W
Gene expression profile after cardiopulmonary bypass and cardioplegic arrest.
The Journal of thoracic and cardiovascular surgery 2003;126(5):1521-30.
2003: Sebastiani Paola; Lazarus Ross; Weiss Scott T; Kunkel Louis M; Kohane Isaac S; Ramoni Marco F
Minimal haplotype tagging.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9900-5.
2003: Haslett Judith N; Sanoudou Despina; Kho Alvin T; Han Mei; Bennett Richard R; Kohane Isaac S; Beggs Alan H; Kunkel Louis M
Gene expression profiling of Duchenne muscular dystrophy skeletal muscle.
Neurogenetics 2003;4(4):163-71.
2003: Nimgaonkar Ashish; Sanoudou Despina; Butte Atul J; Haslett Judith N; Kunkel Louis M; Beggs Alan H; Kohane Isaac S
Reproducibility of gene expression across generations of Affymetrix microarrays.
BMC bioinformatics 2003;4():27.
2003: Lee Kyungjoon; Kohane Isaac S; Butte Atul J
PGAGENE: integrating quantitative gene-specific results from the NHLBI programs for genomic applications.
Bioinformatics (Oxford, England) 2003;19(6):778-9.
2003: Sanoudou Despina; Haslett Judith N; Kho Alvin T; Guo Shaoqiang; Gazda Hanna T; Greenberg Steven A; Lidov Hart G W; Kohane Isaac S; Kunkel Louis M; Beggs Alan H
Expression profiling reveals altered satellite cell numbers and glycolytic enzyme transcription in nemaline myopathy muscle.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4666-71.
2003: Porter Stephen C; Fleisher Gary R; Kohane Isaac S; Mandl Kenneth D
The value of parental report for diagnosis and management of dehydration in the emergency department.
Annals of emergency medicine 2003;41(2):196-205.
2003: Saluja Sunil K; Kohane Isaac
Localization and characterization of mouse-human alignments within the human genome. Does evolutionary conservation suggest functional importance?
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2003;():994.
2002: Riva A; Kohane I S
SNPper: retrieval and analysis of human SNPs.
Bioinformatics (Oxford, England) 2002;18(12):1681-5.
2002: Park Peter J; Butte Atul J; Kohane Isaac S
Comparing expression profiles of genes with similar promoter regions.
Bioinformatics (Oxford, England) 2002;18(12):1576-84.
2002: Turchin Alexander; Kohane Isaac S
Gene homology resources on the World Wide Web.
Physiological genomics 2002;11(3):165-77.
2002: Haslett Judith N; Sanoudou Despina; Kho Alvin T; Bennett Richard R; Greenberg Steven A; Kohane Isaac S; Beggs Alan H; Kunkel Louis M
Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):15000-5.
2002: Greenberg S A; Sanoudou D; Haslett J N; Kohane I S; Kunkel L M; Beggs A H; Amato A A
Molecular profiles of inflammatory myopathies.
Neurology 2002;59(8):1170-82.
2002: Ramoni Marco F; Sebastiani Paola; Kohane Isaac S
Cluster analysis of gene expression dynamics.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9121-6.
2002: Zhao Qing; Kho Alvin; Kenney Anna Marie; Yuk Di Dong-in; Kohane Isaac; Rowitch David H
Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5704-9.
2002: Kuo Winston Patrick; Jenssen Tor-Kristian; Butte Atul J; Ohno-Machado Lucila; Kohane Isaac S
Analysis of matched mRNA measurements from two different microarray technologies.
Bioinformatics (Oxford, England) 2002;18(3):405-12.
2002: Kohane Isaac S
The contributions of biomedical informatics to the fight against bioterrorism.
Journal of the American Medical Informatics Association : JAMIA 2002;9(2):116-9.
2002: Kim Ju Han; Kohane Isaac S; Ohno-Machado Lucila
Visualization and evaluation of clusters for exploratory analysis of gene expression data.
Journal of biomedical informatics 2002;35(1):25-36.
2002: Mandl Kenneth D; Feit Shlomit; Larson Cecilia; Kohane Isaac S
Newborn screening program practices in the United States: notification, research, and consent.
Pediatrics 2002;109(2):269-73.
2002: Schachter Asher D; Kohane Isaac S
An unsupervised self-optimizing gene clustering algorithm.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2002;():682-6.
2002: Riva Alberto; Kohane Isaac S
Accessing genomic data through XML-based remote procedure calls.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2002;():662-6.
2002: Cai Zhaohui; Kohane Isaac; Fleisher Gary R; Greenes David S
Computerized reminders to physicians in the emergency department: a web-based system to report late-arriving abnormal laboratory results.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2002;():91-5.
2002: Park Peter J; Tian Lu; Kohane Isaac S
Linking gene expression data with patient survival times using partial least squares.
Bioinformatics (Oxford, England) 2002;18 Suppl 1():S120-7.
2001: Butte A J; Bao L; Reis B Y; Watkins T W; Kohane I S
Comparing the similarity of time-series gene expression using signal processing metrics.
Journal of biomedical informatics 2001;34(6):396-405.
2001: Riva A; Mandl K D; Oh D H; Nigrin D J; Butte A; Szolovits P; Kohane I S
The personal internetworked notary and guardian.
International journal of medical informatics 2001;62(1):27-40.
2001: Mandl K D; Szolovits P; Kohane I S
Public standards and patients' control: how to keep electronic medical records accessible but private.
BMJ (Clinical research ed.) 2001;322(7281):283-7.
2001: Riva A; Kohane I S
A web-based tool to retrieve human genome polymorphisms from public databases.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2001;():558-62.
2001: Porter S C; Kohane I S
Optimal data entry by patients: effects of interface structure and design.
Studies in health technology and informatics 2001;84(Pt 1):141-5.
2000: Greenes D S; Fleisher G R; Kohane I
Potential impact of a computerized system to report late-arriving laboratory results in the emergency department.
Pediatric emergency care 2000;16(5):313-5.
2000: Butte A J; Tamayo P; Slonim D; Golub T R; Kohane I S
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12182-6.
2000: Gonzalez-Heydrich J; DeMaso D R; Irwin C; Steingard R J; Kohane I S; Beardslee W R
Implementation of an electronic medical record system in a pediatric psychopharmacology program.
International journal of medical informatics 2000;57(2-3):109-16.
2000: Mandl K D; Feit S; Peña B M; Kohane I S
Growth and determinants of access in patient e-mail and Internet use.
Archives of pediatrics & adolescent medicine 2000;154(5):508-11.
2000: Porter S C; Silvia M T; Fleisher G R; Kohane I S; Homer C J; Mandl K D
Parents as direct contributors to the medical record: validation of their electronic input.
Annals of emergency medicine 2000;35(4):346-52.
2000: Nigrin D J; Kohane I S
Temporal expressiveness in querying a time-stamp--based clinical database.
Journal of the American Medical Informatics Association : JAMIA 2000;7(2):152-63.
2000: Nigrin D J; Kohane I S
Glucoweb: a case study of secure, remote biomonitoring and communication.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2000;():610-4.
2000: Kohane I S; Altman R B
The new peer review.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2000;():433-7.
2000: Butte A J; Weinstein D A; Kohane I S
Enrolling patients into clinical trials faster using RealTime Recuiting.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2000;():111-5.
1999: Cao C; McIntosh N; Kohane I S; Wang K
Artifact detection in the PO2 and PCO2 time series monitoring data from preterm infants.
Journal of clinical monitoring and computing 1999;15(6):369-78.
1999: Gonzalez-Heydrich J; Steingard R J; Putnam F; Beardslee W; Kohane I S
Using 'off the shelf', computer programs to mine additional insights from published data: diurnal variation in potency of ACTH stimulation of cortisol secretion revealed.
Computer methods and programs in biomedicine 1999;58(3):227-38.
1999: Sun Y; van Wingerde F J; Kohane I S; Harary O; Mandl K D; Salem-Schatz S R; Homer C J
The challenges of automating a real-time clinical practice guideline.
Clinical performance and quality health care 1999;7(1):28-35.
1999: Nigrin D J; Kohane I S
Scaling a data retrieval and mining application to the enterprise-wide level.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1999;():901-5.
1999: Mandl K D; Kohane I S
Healthconnect: clinical grade patient-physician communication.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1999;():849-53.
1999: Butte A J; Kohane I S
Unsupervised knowledge discovery in medical databases using relevance networks.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1999;():711-5.
1999: Cao C; Kohane I S; McIntosh N
Artifact detection in cardiovascular time series monitoring data from preterm infants.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1999;():207-11.
1998: Mandl K D; Kohane I S; Brandt A M
Electronic patient-physician communication: problems and promise.
Annals of internal medicine 1998;129(6):495-500.
1998: Nigrin D J; Kohane I S
Data mining by clinicians.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1998;():957-61.
1998: van Wingerde F J; Sun Y; Harary O; Mandl K D; Salem-Schatz S; Homer C J; Kohane I S
Linking multiple heterogeneous data sources to practice guidelines.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1998;():391-5.
1998: Mandl K D; Katz S B; Kohane I S
Social equity and access to the World Wide Web and E-mail: implications for design and implementation of medical applications.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1998;():215-9.
1997: Rind D M; Kohane I S; Szolovits P; Safran C; Chueh H C; Barnett G O
Maintaining the confidentiality of medical records shared over the Internet and the World Wide Web.
Annals of internal medicine 1997;127(2):138-41.
1997: Wang K; van Wingerde F J; Bradshaw K; Szolovits P; Kohane I
A Java-based multi-institutional medical information retrieval system.
Proceedings : a conference of the American Medical Informatics Association / ... AMIA Annual Fall Symposium. AMIA Fall Symposium 1997;():538-42.
1996: Haimowitz I J; Kohane I S
Managing temporal worlds for medical trend diagnosis.
Artificial intelligence in medicine 1996;8(3):299-321.
1996: Kohane I S
Exploring the functions of World Wide Web-based electronic medical record systems.
M.D. computing : computers in medical practice 1996;13(4):339-46.
1996: Kohane I S; Greenspun P; Fackler J; Cimino C; Szolovits P
Building national electronic medical record systems via the World Wide Web.
Journal of the American Medical Informatics Association : JAMIA 1996;3(3):191-207.
1996: Wang K; Kohane I; Bradshaw K L; Fackler J
A real time patient monitoring system on the World Wide Web.
Proceedings : a conference of the American Medical Informatics Association / ... AMIA Annual Fall Symposium. AMIA Fall Symposium 1996;():729-32.
1996: van Wingerde F J; Schindler J; Kilbridge P; Szolovits P; Safran C; Rind D; Murphy S; Barnett G O; Kohane I S
Using HL7 and the World Wide Web for unifying patient data from remote databases.
Proceedings : a conference of the American Medical Informatics Association / ... AMIA Annual Fall Symposium. AMIA Fall Symposium 1996;():643-7.
1996: Kohane I S; van Wingerde F J; Fackler J C; Cimino C; Kilbridge P; Murphy S; Chueh H; Rind D; Safran C; Barnett O; Szolovits P
Sharing electronic medical records across multiple heterogeneous and competing institutions.
Proceedings : a conference of the American Medical Informatics Association / ... AMIA Annual Fall Symposium. AMIA Fall Symposium 1996;():608-12.
1995: Haimowitz I J; Le P P; Kohane I S
Clinical monitoring using regression-based trend templates.
Artificial intelligence in medicine 1995;7(6):473-96.
1995: Gordon C M; Rowitch D H; Mitchell M L; Kohane I S
Topical iodine and neonatal hypothyroidism.
Archives of pediatrics & adolescent medicine 1995;149(12):1336-9.
1995: Waisel D B; Fackler J C; Brunner J X; Kohane I
PEFIOS: an expert closed-loop oxygenation algorithm.
Medinfo. MEDINFO 1995;8 Pt 2():1132-6.
1995: Le P P; Kohane I S; Weeks J C
Using a pen-based computer to collect health-related quality of life and utilities information.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1995;():839-43.
1995: Hinds A; Greenspun P; Kohane I S
WHAM!: a forms constructor for medical record access via the World Wide Web.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1995;():116-20.
1994: Szolovits P; Kohane I
Against simple universal health-care identifiers.
Journal of the American Medical Informatics Association : JAMIA 1994;1(4):316-9.
1994: Emanuel R L; Robinson B G; Seely E W; Graves S W; Kohane I; Saltzman D; Barbieri R; Majzoub J A
Corticotrophin releasing hormone levels in human plasma and amniotic fluid during gestation.
Clinical endocrinology 1994;40(2):257-62.
1994: Fackler J; Kohane I
Monitor-driven data visualization: SmartDisplay.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1994;():939-43.
1994: Sun Y; Kohane I; Stark A R
Fuzzy logic assisted control of inspired oxygen in ventilated newborn infants.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1994;():757-61.
1994: Kohane I S
Getting the data in: three year experience with a pediatric electronic medical record system.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1994;():457-61.
1994: Gonzalez-Heydrich J; Steingard R J; Kohane I
A computer simulation of the hypothalamic-pituitary-adrenal axis.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1994;():1010.
1993: Kohane I S; Haimowitz I J
Hypothesis-driven data abstraction with trend templates.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1993;():444-8.
1991: Haimowitz I J; Kohane I S
Influences on the performance of hospital clinical event monitoring.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1991;():614-8.

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