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Isaac Kohane

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TOP 3
Christopher G Chute; Isaac S Kohane
Genomic medicine, health information technology, and patient care.
Isaac S Kohane
Automating the study of population variation of electrocardiographic features.
Wouter S Hoogenboom; Susanne E Churchill; Vivian S Gainer; Isaac S Kohane; Shawn N Murphy; Roy H Perlis; Martha E Shenton; Jordan W Smoller; Qing Zeng-Treitler; Dan V Iosifescu
Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: a pilot study.

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All Publications

2013: Christopher G Chute; Isaac S Kohane
Genomic medicine, health information technology, and patient care.
JAMA : the journal of the American Medical Association 2013;309(14):1467-8.
2013: Isaac S Kohane
Automating the study of population variation of electrocardiographic features.
Circulation 2013;127(13):1357-8.
2013: Wouter S Hoogenboom; Susanne E Churchill; Vivian S Gainer; Isaac S Kohane; Shawn N Murphy; Roy H Perlis; Martha E Shenton; Jordan W Smoller; Qing Zeng-Treitler; Dan V Iosifescu
Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: a pilot study.
Psychiatry research 2013;211(3):202-13.
2013: Russ B Altman; Ellen Wright Clayton; Isaac S Kohane; Bradley A Malin; Dan M Roden
Data re-identification: societal safeguards.
Science (New York, N.Y.) 2013;339(6123):1032-3.
2013: Andrew J McMurry; Shawn N Murphy; John Orechia; William W Simons; Philip Trevvett; Nich Wattanasin; Griffin Weber; Jonathan Bickel; Susanne Churchill; Clint Gilbert; Douglas MacFadden; Isaac S Kohane
SHRINE: enabling nationally scalable multi-site disease studies.
PloS one 2013;8(3):e55811.
2013: Victor M Castro; Susanne E Churchill; Caitlin C Clements; Jane L Erb; Maurizio Fava; Vivian S Gainer; Dan V Iosifescu; Isaac S Kohane; Shawn N Murphy; Jordan W Smoller; Jeffrey B Weilburg; Roy H Perlis
QT interval and antidepressant use: a cross sectional study of electronic health records.
BMJ (Clinical research ed.) 2013;346():f288.
2012: Isaac S Kohane; Jeffrey M Drazen; Edward W Campion
A glimpse of the next 100 years in medicine.
The New England journal of medicine 2012;367(26):2538-9.
2012: Patience J Gallagher; Dan V Iosifescu; Isaac S Kohane; Shawn N Murphy; Victor Castro; Susanne E Churchill; Maurizio Fava; Vivian S Gainer; Jordan W Smoller; Jeffrey B Weilburg; Roy H Perlis
Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study.
The American journal of psychiatry 2012;169(10):1065-72.
2012: Daniel R Masys; Paul A Fearn; Paul A Harris; Isaac S Kohane
Designing a public square for research computing.
Science translational medicine 2012;4(149):149fs32.
2012: Kenneth D Mandl; J Michael McCoy; Shawn N Murphy; Rachel L Ramoni; Ben Adida; Elmer Victor Bernstam; David A Kreda; Joshua C Mandel; Isaac S Kohane
The SMART Platform: early experience enabling substitutable applications for electronic health records.
Journal of the American Medical Informatics Association : JAMIA 2012;19(4):597-603.
2012: Kenneth D Mandl; Isaac S Kohane
Escaping the EHR trap--the future of health IT.
The New England journal of medicine 2012;366(24):2240-2.
2012: Kenneth D Mandl; Ramin Khorasani; Isaac S Kohane
Meaningful use of electronic health records.
Health affairs (Project Hope) 2012;31(6):1365; author reply 1366.
2012: Daniel R Masys; Dina N Paltoo; George J Papanicolaou; Neil F Abernethy; Nicholas R Anderson; Mark A Hoffman; Gail P Jarvik; Isaac S Kohane; HOWARD LEVY
Technical desiderata for the integration of genomic data into Electronic Health Records.
Journal of biomedical informatics 2012;45(3):419-22.
2012: Isaac S Kohane; Jay Shendure
What's a Genome Worth?
Science translational medicine 2012;4(133):133fs13.
2012: Patrick R Schmid; Isaac S Kohane; Nathan P Palmer; Bonnie Berger
Making sense out of massive data by going beyond differential expression.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(15):5594-9.
2012: Susan M Wolf; Laura M Beskow; Mildred K Cho; Michael F Christman; Brittney N Crock; Robert C Green; Ralph Hall; Judy Illes; Jeffrey P Kahn; Moira Keane; Bartha M Knoppers; Barbara A Koenig; Isaac S Kohane; Frances Lawrenz; Bonnie Leroy; Karen J Maschke; William McGeveran; Pilar Ossorio; Lisa S Parker; Gloria M Petersen; Henry S Richardson; Joan A Scott; Sharon F Terry; Brian Van Ness; Benjamin S Wilfond; Wendy A Wolf
Managing incidental findings and research results in genomic research involving biobanks and archived data sets.
Genetics in medicine : official journal of the American College of Medical Genetics 2012;14(4):361-84.
2012: Isaac S Kohane; Michael Hsing; Sek Won Kong
Taxonomizing, sizing, and overcoming the incidentalome.
Genetics in medicine : official journal of the American College of Medical Genetics 2012;14(4):399-404.
2012: Isaac S Kohane; Susanne E Churchill; Shawn N Murphy
A translational engine at the national scale: informatics for integrating biology and the bedside.
Journal of the American Medical Informatics Association : JAMIA 2012;19(2):181-5.
2012: E Helman; K Naxerova; Isaac S Kohane
DNA hypermethylation in lung cancer is targeted at differentiation-associated genes.
Oncogene 2012;31(9):1181-8.
2012: Isaac S Kohane; Vladimir I Valtchinov
Quantifying the white blood cell transcriptome as an accessible window to the multiorgan transcriptome.
Bioinformatics (Oxford, England) 2012;28(4):538-45.
2012: Isaac S Kohane
Interview with Isaac S. Kohane conducted by Sarah Miller.
Pharmacogenomics 2012;13(3):257-60.
2012: Isaac S Kohane
(Mis)treating the pharmacogenetic incidentalome.
Nature reviews. Drug discovery 2012;11(2):89-90.
2012: Sek Won Kong; Louis M Kunkel; In-Hee Lee; Kathryn R Lowe; Kimberly Madison; Jillian McCarthy; Andrea Mora; Leonard Rappaport; Adrianna Saada; Yuko Shimizu-Motohashi; Stephanie J Brewster; Malcolm G Campbell; Christin D Collins; Jessica Egan; Ally Eran; Michal Galdzicki; Ellen Hanson; Heather K Harris; Ingrid A Holm; Rachel Hundley; Isaac S Kohane
Characteristics and predictive value of blood transcriptome signature in males with autism spectrum disorders.
PloS one 2012;7(12):e49475.
2012: Isaac S Kohane; Louis Kunkel; Douglas MacFadden; Andrew McMurry; Shawn Murphy; Leonard Rappaport; Sarah Spence; Nich Wattanasin; Griffin Weber; Jonathan Bickel; Susanne Churchill
The co-morbidity burden of children and young adults with autism spectrum disorders.
PloS one 2012;7(4):e33224.
2012: Victor M Castro; Susanne E Churchill; Caitlin C Clements; Maurizio Fava; Vivian S Gainer; Patience J Gallagher; Dan V Iosifescu; Isaac S Kohane; Shawn N Murphy; Jordan W Smoller; Jeffrey B Weilburg; Roy H Perlis
Incident user cohort study of risk for gastrointestinal bleed and stroke in individuals with major depressive disorder treated with antidepressants.
BMJ open 2012;2(2):e000544.
2012: R H Perlis; Jeffrey B Weilburg; Q Zeng; Tianxi Cai; V M Castro; S E Churchill; Maurizio Fava; V S Gainer; P J Gallagher; Sergey Goryachev; D V Iosifescu; Isaac S Kohane; J Minnier; Shawn N Murphy; Jordan W Smoller
Using electronic medical records to enable large-scale studies in psychiatry: treatment resistant depression as a model.
Psychological medicine 2012;42(1):41-50.
2011: Elisa Fossale; James Gusella; Isaac S Kohane; Marcy E MacDonald; Ihn Sik Seong; Toshi Shioda; Vanessa C Wheeler; Kathryn R Coser; Jong-Min Lee
Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative.
Human molecular genetics 2011;20(21):4258-67.
2011: Fulvia Ferrazzi; Isaac S Kohane; Annie P Moseman; Riccardo Bellazzi; Felix B Engel; Erxi Wu; Marco F Ramoni
Inferring cell cycle feedback regulation from gene expression data.
Journal of biomedical informatics 2011;44(4):565-75.
2011: Jessie C Jacobsen; Isaac S Kohane; Kathryn R Coser; Gillian C Gregory; James Gusella; Marcy E MacDonald; Vidya Murthy; Ihn Sik Seong; Toshi Shioda; Morgan N Thompson; Juliana M Woda; Jong-Min Lee
HD CAG-correlated gene expression changes support a simple dominant gain of function.
Human molecular genetics 2011;20(14):2846-60.
2011: Nicholas Tatonetti; P S Tsau; P Yue; P S Tsao; V Castro; J C Denny; G H Fernald; Isaac S Kohane; G Krishnan; Shawn N Murphy; Dan Mark Roden; Russ B Altman
Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels.
Clinical pharmacology and therapeutics 2011;90(1):133-42.
2011: Isaac S Kohane; Peter Szolovits
Marco Ramoni: an appreciation of academic achievement.
Journal of the American Medical Informatics Association : JAMIA 2011;18(4):367-9.
2011: Isaac S Kohane
Using electronic health records to drive discovery in disease genomics.
Nature reviews. Genetics 2011;12(6):417-28.
2011: Asher D Schachter; Isaac S Kohane
Drug target-gene signatures that predict teratogenicity are enriched for developmentally related genes.
Reproductive toxicology (Elmsford, N.Y.) 2011;31(4):562-9.
2011: Blanca E Himes; Barbara J Klanderman; Isaac S Kohane; Scott T Weiss
Assessing the reproducibility of asthma genome-wide association studies in a general clinical population.
The Journal of allergy and clinical immunology 2011;127(4):1067-9.
2011: Mark Y Tong; Christopher A Cassa; Isaac S Kohane
Automated validation of genetic variants from large databases: ensuring that variant references refer to the same genomic locations.
Bioinformatics (Oxford, England) 2011;27(6):891-3.
2011: Isaac S Kohane; David M Margulies
Counterpoint: Do not opine before it's time.
Nature biotechnology 2011;29(3):218-9.
2011: J-Y Jung; Isaac S Kohane; Dennis P Wall
Identification of autoimmune gene signatures in autism.
Translational psychiatry 2011;1():e63.
2011: Ting Gong; Nicole Hartmann; Isaac S Kohane; Martin Letzkus; Staedtler Frank; Sandrine Bongiovanni; Volker Brinkmann; Joseph D Szustakowski
Optimal deconvolution of transcriptional profiling data using quadratic programming with application to complex clinical blood samples.
PloS one 2011;6(11):e27156.
2011: Isaac S Kohane
No small matter: qualitatively distinct challenges of pediatric genomic studies.
Genome medicine 2011;3(9):62.
2011: Ze Tian; Fengfei Wang; Peigen Xiao; Junshan Yang; Andrius Kazlauskas; Isaac S Kohane; Hetian Lei; Jie Shen; Erxi Wu
Cambogin is preferentially cytotoxic to cells expressing PDGFR.
PloS one 2011;6(6):e21370.
2011: Boian Alexandrov; Vlad I Valtchinov; Ludmil B Alexandrov; Vladimir Gelev; Yossi Dagon; Jonathan Bock; Isaac S Kohane; Kim Rasmussen; Alan R Bishop; Anny Usheva
DNA dynamics is likely to be a factor in the genomic nucleotide repeats expansions related to diseases.
PloS one 2011;6(5):e19800.
2010: Isaac S Kohane; Patrick L Taylor
Multidimensional results reporting to participants in genomic studies: getting it right.
Science translational medicine 2010;2(37):37cm19.
2010: Shawn N Murphy; Griffin Weber; Michael Mendis; Vivian Gainer; Henry C Chueh; Susanne Churchill; Isaac S Kohane
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2).
Journal of the American Medical Informatics Association : JAMIA 2010;17(2):124-30.
2010: John S Brownstein; Shawn N Murphy; Allison B Goldfine; Richard W Grant; Margarita Sordo; Vivian Gainer; Judith A Colecchi; Anil Dubey; David M Nathan; John Glaser; Isaac S Kohane
Rapid identification of myocardial infarction risk associated with diabetes medications using electronic medical records.
Diabetes care 2010;33(3):526-31.
2010: Ben Adida; Arjun Sanyal; Steve Zabak; Isaac S Kohane; Kenneth D Mandl
Indivo x: developing a fully substitutable personally controlled health record platform.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2010;2010():6-10.
2010: Kyungjoon Lee; John S Brownstein; Richard G Mills; Isaac S Kohane
Does collocation inform the impact of collaboration?
PloS one 2010;5(12):e14279.
2010: Alvin T Kho; Soumyaroop Bhattacharya; Kelan G Tantisira; Vincent J Carey; Roger Gaedigk; J Steven Leeder; Isaac S Kohane; Scott T Weiss; Thomas J Mariani
Transcriptomic analysis of human lung development.
American journal of respiratory and critical care medicine 2010;181(1):54-63.
2009: Peter J Park; Sek Won Kong; Toma Tebaldi; Weil R Lai; Simon Kasif; Isaac S Kohane
Integration of heterogeneous expression data sets extends the role of the retinol pathway in diabetes and insulin resistance.
Bioinformatics (Oxford, England) 2009;25(23):3121-7.
2009: Kenneth L Roach; Kevin R King; Basak E Uygun; Isaac S Kohane; Martin L Yarmush; Mehmet Toner
High throughput single cell bioinformatics.
Biotechnology progress 2009;25(6):1772-9.
2009: Adam Davis; Isaac S Kohane
Expression differences by continent of origin point to the immortalization process.
Human molecular genetics 2009;18(20):3864-75.
2009: Griffin M Weber; Shawn N Murphy; Andrew J McMurry; Douglas Macfadden; Daniel J Nigrin; Susanne Churchill; Isaac S Kohane
The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories.
Journal of the American Medical Informatics Association : JAMIA 2009;16(5):624-30.
2009: Kenneth L Roach; Kevin R King; Korkut Uygun; Steven C Hand; Isaac S Kohane; Martin L Yarmush; Mehmet Toner
High-throughput single cell arrays as a novel tool in biopreservation.
Cryobiology 2009;58(3):315-21.
2009: Blanca E Himes; Yi Dai; Isaac S Kohane; Scott Weiss; Marco F Ramoni
Prediction of chronic obstructive pulmonary disease (COPD) in asthma patients using electronic medical records.
Journal of the American Medical Informatics Association : JAMIA 2009;16(3):371-9.
2009: Ze Tian; Ning An; Bin Zhou; Peigen Xiao; Isaac S Kohane; Erxi Wu
Cytotoxic diarylheptanoid induces cell cycle arrest and apoptosis via increasing ATF3 and stabilizing p53 in SH-SY5Y cells.
Cancer chemotherapy and pharmacology 2009;63(6):1131-9.
2009: Alal Eran; Kaitlin R Graham; Kayla Vatalaro; Jillian McCarthy; Christin Collins; Heather Peters; Stephanie J Brewster; Ellen Hanson; Rachel Hundley; Leonard Rappaport; Ingrid A Holm; Isaac S Kohane; Louis Kunkel
Comment on "Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients".
The Journal of clinical investigation 2009;119(4):679-80; author reply 680-1.
2009: Kenneth D Mandl; Isaac S Kohane
No small change for the health information economy.
The New England journal of medicine 2009;360(13):1278-81.
2009: Dennis P Wall; F J Esteban; T F Deluca; M Huyck; T Monaghan; Nieves Velez de Mendizabal; J Goñí; Isaac S Kohane
Comparative analysis of neurological disorders focuses genome-wide search for autism genes.
Genomics 2009;93(2):120-9.
2009: Isaac S Kohane
Ten thousand views of bioinformatics: a bibliome perspective.
Yearbook of medical informatics 2009;():113-6.
2009: Ben Y Reis; Isaac S Kohane; Kenneth D Mandl
Longitudinal histories as predictors of future diagnoses of domestic abuse: modelling study.
BMJ (Clinical research ed.) 2009;339():b3677.
2009: Ze Tian; Nathan Palmer; Patrick Schmid; Hui Yao; Michal Galdzicki; Bonnie Berger; Erxi Wu; Isaac S Kohane
A practical platform for blood biomarker study by using global gene expression profiling of peripheral whole blood.
PloS one 2009;4(4):e5157.
2009: Isaac S Kohane
The twin questions of personalized medicine: who are you and whom do you most resemble?
Genome medicine 2009;1(1):4.
2008: Kenneth D Mandl; Isaac S Kohane
Tectonic shifts in the health information economy.
The New England journal of medicine 2008;358(16):1732-7.
2008: Erxi Wu; Nathan Palmer; Ze Tian; Annie P Moseman; Michal Galdzicki; Xuetao Wang; Bonnie Berger; Hongbing Zhang; Isaac S Kohane
Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells.
PloS one 2008;3(11):e3794.
2008: Blanca E Himes; Isaac S Kohane; Marco F Ramoni; Scott Weiss
Characterization of patients who suffer asthma exacerbations using data extracted from electronic medical records.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2008;():308-12.
2008: Christopher A Cassa; Brian Schmidt; Isaac S Kohane; Kenneth D Mandl
My sister's keeper?: genomic research and the identifiability of siblings.
BMC medical genomics 2008;1():32.
2008: Kamila Naxerova; Carol Bult; Anne Peaston; Karen Fancher; Barbara B Knowles; Simon Kasif; Isaac S Kohane
Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers.
Genome biology 2008;9(7):R108.
2008: Ivo D Dinov; Daniel Rubin; William Lorensen; Jonathan Dugan; Jeff Ma; Shawn Murphy; Beth Kirschner; William Bug; Michael Sherman; Aris Floratos; David Kennedy; H V Jagadish; Jeanette Schmidt; Brian D Athey; Andrea Califano; Mark Musen; Russ Altman; Ron Kikinis; Isaac S Kohane; Scott Delp; D Stott Parker; Arthur W Toga
iTools: a framework for classification, categorization and integration of computational biology resources.
PloS one 2008;3(5):e2265.
2008: Ze Tian; Jie Shen; Annie P Moseman; Quanli Yang; Junshan Yang; Peigen Xiao; Erxi Wu; Isaac S Kohane
Dulxanthone A induces cell cycle arrest and apoptosis via up-regulation of p53 through mitochondrial pathway in HepG2 cells.
International journal of cancer. Journal international du cancer 2008;122(1):31-8.
2007: Iris Eisenberg; Alal Eran; Ichizo Nishino; Maurizio Moggio; Costanza Lamperti; Anthony A Amato; Hart G W Lidov; Peter B Kang; Kathryn N North; Stella Mitrani-Rosenbaum; Kevin M Flanigan; Lori A Neely; Duncan Whitney; Alan H Beggs; Isaac S Kohane; Louis Kunkel
Distinctive patterns of microRNA expression in primary muscular disorders.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(43):17016-21.
2007: Basel Ramlawi; Hasan H Otu; James L Rudolph; Shigetoshi Mieno; Isaac S Kohane; Handan Can; Towia Libermann; Edward R Marcantonio; Cesario Bianchi; Frank W Sellke
Genomic expression pathways associated with brain injury after cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 2007;134(4):996-1005.
2007: Thomas A Drake; Jonathan Braun; Alberto M Marchevsky; Isaac S Kohane; Christopher Fletcher; Henry Chueh; Bruce A Beckwith; David A Berkowicz; Frank Kuo; Qing T Zeng; Ulysses J Balis; Ana Holzbach; Andrew McMurry; Connie E Gee; Clement McDonald; Gunther Schadow; Mary Davis; Eyas M Hattab; Lonnie Blevins; John Hook; Michael Becich; Rebecca S Crowley; Sheila E Taube; Jules Berman
A system for sharing routine surgical pathology specimens across institutions: the Shared Pathology Informatics Network.
Human pathology 2007;38(8):1212-25.
2007: Andrew J McMurry; Clint A Gilbert; Ben Y Reis; Henry C Chueh; Isaac S Kohane; Kenneth D Mandl
A self-scaling, distributed information architecture for public health, research, and clinical care.
Journal of the American Medical Informatics Association : JAMIA 2007;14(4):527-33.
2007: Ben Y Reis; Isaac S Kohane; Kenneth D Mandl
An epidemiological network model for disease outbreak detection.
PLoS medicine 2007;4(6):e210.
2007: Manway Liu; Arthur Liberzon; Sek Won Kong; Weil R Lai; Peter J Park; Isaac S Kohane; Simon Kasif
Network-based analysis of affected biological processes in type 2 diabetes models.
PLoS genetics 2007;3(6):e96.
2007: Alexander Turchin; Nikheel S Kolatkar; Merri L Pendergrass; Isaac S Kohane
Computational analysis of non-adherence and non-attendance using the text of narrative physician notes in the electronic medical record.
Medical informatics and the Internet in medicine 2007;32(2):93-102.
2007: Isaac S Kohane; Kenneth D Mandl; Patrick L Taylor; Ingrid A Holm; Daniel J Nigrin; Louis Kunkel
Medicine. Reestablishing the researcher-patient compact.
Science (New York, N.Y.) 2007;316(5826):836-7.
2007: Hidenori Inaoka; Yutaka Fukuoka; Isaac S Kohane
Evidence of spatially bound gene regulation in Mus musculus: decreased gene expression proximal to microRNA genomic location.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5020-5.
2007: Shawn N Murphy; Michael Mendis; Kristel Hackett; Rajesh Kuttan; Wensong Pan; Lori C Phillips; Vivian Gainer; David Berkowicz; John Glaser; Isaac S Kohane; Henry C Chueh
Architecture of the open-source clinical research chart from Informatics for Integrating Biology and the Bedside.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2007;():548-52.
2007: Jennifer Cohen; Linda J Van Marter; Yao Sun; Elizabeth N Allred; Alan Leviton; Isaac S Kohane
Perturbation of gene expression of the chromatin remodeling pathway in premature newborns at risk for bronchopulmonary dysplasia.
Genome biology 2007;8(10):R210.
2007: John S Brownstein; Margarita Sordo; Isaac S Kohane; Kenneth D Mandl
The tell-tale heart: population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction.
PloS one 2007;2(9):e840.
2007: Joseph Loscalzo; Isaac S Kohane; Albert-Laszlo Barabasi
Human disease classification in the postgenomic era: a complex systems approach to human pathobiology.
Molecular systems biology 2007;3():124.
2007: Ashokkumar Patel; Dilipkumar Gupta; David Seligson; Eyas M Hattab; Ulysses J Balis; Thomas M Ulbright; Isaac S Kohane; Jules J Berman; John R Gilbertson; Sarah Dry; Osvaldo Schirripa; Hong Yu; Michael Becich; Anil V Parwani
Availability and quality of paraffin blocks identified in pathology archives: a multi-institutional study by the Shared Pathology Informatics Network (SPIN).
BMC cancer 2007;7():37.
2007: Dominic J Allocco; QING SONG; Gary H Gibbons; Marco F Ramoni; Isaac S Kohane
Geography and genography: prediction of continental origin using randomly selected single nucleotide polymorphisms.
BMC genomics 2007;8():68.
2006: Eric K Chu; Jason Cheng; John S Foley; Brigham H Mecham; Caroline A Owen; Kathleen J Haley; Thomas J Mariani; Isaac S Kohane; Daniel J Tschumperlin; Jeffrey M Drazen
Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells.
American journal of respiratory cell and molecular biology 2006;35(6):628-38.
2006: Natasha Y Frank; Alvin T Kho; Tobias Schatton; George F Murphy; Michael J Molloy; Qian Zhan; Marco F Ramoni; Markus Frank; Isaac S Kohane; Emanuela Gussoni
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin.
The Journal of cell biology 2006;175(1):99-110.
2006: Scott L Carter; Aron C Eklund; Isaac S Kohane; Lyndsay N Harris; Zoltan Szallasi
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.
Nature genetics 2006;38(9):1043-8.
2006: Hanna T Gazda; Alvin T Kho; Despina Sanoudou; Jan M Zaucha; Isaac S Kohane; Colin A Sieff; Alan H Beggs
Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia.
Stem cells (Dayton, Ohio) 2006;24(9):2034-44.
2006: Kenneth E Hung; Alvin T Kho; David A Sarracino; Larissa Georgeon Richard; Bryan Krastins; Sara Forrester; Brian B Haab; Isaac S Kohane; Raju Kucherlapati
Mass spectrometry-based study of the plasma proteome in a mouse intestinal tumor model.
Journal of proteome research 2006;5(8):1866-78.
2006: Isaac S Kohane; Daniel R Masys; Russ B Altman
The incidentalome: a threat to genomic medicine.
JAMA : the journal of the American Medical Association 2006;296(2):212-5.
2006: Hongye Liu; Alvin T Kho; Isaac S Kohane; Yao Sun
Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development.
PLoS medicine 2006;3(7):e232.
2006: Alexander Turchin; Christine Z Guo; Gail K Adler; Vincent Ricchiuti; Isaac S Kohane; Gordon H Williams
Effect of acute aldosterone administration on gene expression profile in the heart.
Endocrinology 2006;147(7):3183-9.
2006: Paola Sebastiani; Kenneth D Mandl; Peter Szolovits; Isaac S Kohane; Marco F Ramoni
A Bayesian dynamic model for influenza surveillance.
Statistics in medicine 2006;25(11):1803-16; discussion 1817-25.
2006: Voichita D Marinescu; Isaac S Kohane; Tae Kyoung Kim; David A Harmin; Michael E Greenberg; Alberto Riva
START: an automated tool for serial analysis of chromatin occupancy data.
Bioinformatics (Oxford, England) 2006;22(8):999-1001.
2006: William W Simons; John Halamka; Isaac S Kohane; Daniel J Nigrin; Nathan Finstein; Kenneth D Mandl
Integration of the personally controlled electronic medical record into regional inter-regional data exchanges: a national demonstration.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2006;():1099.
2006: Shawn N Murphy; Michael E Mendis; David A Berkowitz; Isaac S Kohane; Henry C Chueh
Integration of clinical and genetic data in the i2b2 architecture.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2006;():1040.
2006: Kristel L Hackett; Isaac S Kohane; Henry C Chueh; Shawn N Murphy
Mapping tool for maintaining vocabulary relationships.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2006;():939.
2006: John S Brownstein; Christopher A Cassa; Isaac S Kohane; Kenneth D Mandl
An unsupervised classification method for inferring original case locations from low-resolution disease maps.
International journal of health geographics 2006;5():56.
2006: Ben Adida; Isaac S Kohane
GenePING: secure, scalable management of personal genomic data.
BMC genomics 2006;7():93.
2006: Alvin T Kho; Peter B Kang; Isaac S Kohane; Louis Kunkel
Transcriptome-scale similarities between mouse and human skeletal muscles with normal and myopathic phenotypes.
BMC musculoskeletal disorders 2006;7():23.
2006: Hidenori Inaoka; Yutaka Fukuoka; Isaac S Kohane
Lower expression of genes near microRNA in C. elegans germline.
BMC bioinformatics 2006;7():112.
2006: Atul Butte; Isaac S Kohane
Creation and implications of a phenome-genome network.
Nature biotechnology 2006;24(1):55-62.
2005: Asher D Schachter; Takaharu Ichimura; Isaac S Kohane
Chromosomes 18 and X are quantitative trait loci for nephrotic-range proteinuria in rats.
Pediatric nephrology (Berlin, Germany) 2005;20(12):1717-23.
2005: Isaac S Kohane; Russ B Altman
Health-information altruists--a potentially critical resource.
The New England journal of medicine 2005;353(19):2074-7.
2005: Judith N Haslett; Peter B Kang; Mei Han; Alvin T Kho; Despina Sanoudou; Jay Volinski; Alan H Beggs; Isaac S Kohane; Louis Kunkel
The influence of muscle type and dystrophin deficiency on murine expression profiles.
Mammalian genome : official journal of the International Mammalian Genome Society 2005;16(10):739-48.
2005: Lu Tian; Steven A Greenberg; Sek Won Kong; Josiah Altschuler; Isaac S Kohane; Peter J Park
Discovering statistically significant pathways in expression profiling studies.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13544-9.
2005: Alexander Turchin; Isaac S Kohane; Merri L Pendergrass
Identification of patients with diabetes from the text of physician notes in the electronic medical record.
Diabetes care 2005;28(7):1794-5.
2005: Sek Won Kong; Kyu-Baek Hwang; Richard D Kim; Byoung-Tak Zhang; Steven A Greenberg; Isaac S Kohane; Peter J Park
CrossChip: a system supporting comparative analysis of different generations of Affymetrix arrays.
Bioinformatics (Oxford, England) 2005;21(9):2116-7.
2005: Ulrich Sax; Isaac S Kohane; Kenneth D Mandl
Wireless technology infrastructures for authentication of patients: PKI that rings.
Journal of the American Medical Informatics Association : JAMIA 2005;12(3):263-8.
2005: Stephen C Porter; Isaac S Kohane; Donald A Goldmann
Parents as partners in obtaining the medication history.
Journal of the American Medical Informatics Association : JAMIA 2005;12(3):299-305.
2005: John S Brownstein; Christopher A Cassa; Isaac S Kohane; Kenneth D Mandl
Reverse geocoding: concerns about patient confidentiality in the display of geospatial health data.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2005;():905.
2005: Alexander Turchin; Merri L Pendergrass; Isaac S Kohane
DITTO - a tool for identification of patient cohorts from the text of physician notes in the electronic medical record.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2005;():744-8.
2005: Soohyun Lee; Isaac S Kohane; Simon Kasif
Genes involved in complex adaptive processes tend to have highly conserved upstream regions in mammalian genomes.
BMC genomics 2005;6():168.
2005: Cecily J Wolfe; Isaac S Kohane; Atul Butte
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks.
BMC bioinformatics 2005;6():227.
2005: Scott L Carter; Aron C Eklund; Brigham H Mecham; Isaac S Kohane; Zoltan Szallasi
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in cancer-associated gene expression measurements.
BMC bioinformatics 2005;6():107.
2005: Voichita D Marinescu; Isaac S Kohane; Alberto Riva
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes.
BMC bioinformatics 2005;6():79.
2005: Voichita D Marinescu; Isaac S Kohane; Alberto Riva
The MAPPER database: a multi-genome catalog of putative transcription factor binding sites.
Nucleic acids research 2005;33(Database issue):D91-7.
2005: William W Simons; Kenneth D Mandl; Isaac S Kohane
The PING personally controlled electronic medical record system: technical architecture.
Journal of the American Medical Informatics Association : JAMIA 2005;12(1):47-54.
2004: Rosalyn M Adam; Samuel H Eaton; Carlos R Estrada; Ashish Nimgaonkar; Shu-Ching Shih; Lois E H Smith; Isaac S Kohane; Darius J Bägli; Michael R Freeman
Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells.
Physiological genomics 2004;20(1):36-44.
2004: Stephen C Porter; Zhaohui Cai; William Gribbons; Donald A Goldmann; Isaac S Kohane
The asthma kiosk: a patient-centered technology for collaborative decision support in the emergency department.
Journal of the American Medical Informatics Association : JAMIA 2004;11(6):458-67.
2004: Pierre Voisine; Marc Ruel; Tanveer A Khan; Cesario Bianchi; Shu-Hua Xu; Isaac S Kohane; Towia Libermann; Hasan H Otu; Alan Saltiel; Frank W Sellke
Differences in gene expression profiles of diabetic and nondiabetic patients undergoing cardiopulmonary bypass and cardioplegic arrest.
Circulation 2004;110(11 Suppl 1):II280-6.
2004: Brigham H Mecham; Daniel Z Wetmore; Zoltan Szallasi; Yoel Sadovsky; Isaac S Kohane; Thomas J Mariani
Increased measurement accuracy for sequence-verified microarray probes.
Physiological genomics 2004;18(3):308-15.
2004: Zhaohui Cai; Eric F Tsung; Voichita D Marinescu; Marco F Ramoni; Alberto Riva; Isaac S Kohane
Bayesian approach to discovering pathogenic SNPs in conserved protein domains.
Human mutation 2004;24(2):178-84.
2004: Alan S Lader; Marco F Ramoni; Bruce R Zetter; Isaac S Kohane; David J Kwiatkowski
Identification of a transcriptional profile associated with in vitro invasion in non-small cell lung cancer cell lines.
Cancer biology & therapy 2004;3(7):624-31.
2004: Charles P Friedman; Russ B Altman; Isaac S Kohane; Kathleen A McCormick; Perry L Miller; Judy Ozbolt; Edward H Shortliffe; Gary stormo; M Cleat Szczepaniak; David Tuck; Jeffrey Williamson
Training the next generation of informaticians: the impact of "BISTI" and bioinformatics--a report from the American College of Medical Informatics.
Journal of the American Medical Informatics Association : JAMIA 2004;11(3):167-72.
2004: Despina Sanoudou; Leslie A Frieden; Judith N Haslett; Alvin T Kho; Steven A Greenberg; Isaac S Kohane; Louis Kunkel; Alan H Beggs
Molecular classification of nemaline myopathies: "nontyping" specimens exhibit unique patterns of gene expression.
Neurobiology of disease 2004;15(3):590-600.
2004: Alberto Riva; Isaac S Kohane
A SNP-centric database for the investigation of the human genome.
BMC bioinformatics 2004;5():33.
2004: Alvin T Kho; Qing Zhao; Zhaohui Cai; Atul Butte; John Y H Kim; Scott L Pomeroy; David H Rowitch; Isaac S Kohane
Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers.
Genes & development 2004;18(6):629-40.
2004: Dominic J Allocco; Isaac S Kohane; Atul Butte
Quantifying the relationship between co-expression, co-regulation and gene function.
BMC bioinformatics 2004;5():18.
2004: Ashish Nimgaonkar; Dilip R Karnad; S Sudarshan; Lucila Ohno-Machado; Isaac S Kohane
Prediction of mortality in an Indian intensive care unit. Comparison between APACHE II and artificial neural networks.
Intensive care medicine 2004;30(2):248-53.
2004: Kinga K Tomczak; Voichita D Marinescu; Marco F Ramoni; Despina Sanoudou; Federica Montanaro; Mei Han; Louis Kunkel; Isaac S Kohane; Alan H Beggs
Expression profiling and identification of novel genes involved in myogenic differentiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(2):403-5.
2004: Yutaka Fukuoka; Hidenori Inaoka; Isaac S Kohane
Inter-species differences of co-expression of neighboring genes in eukaryotic genomes.
BMC genomics 2004;5(1):4.
2004: Gil Alterovitz; Manuel Aivado; Dimitrios Spentzos; Towia Libermann; Marco F Ramoni; Isaac S Kohane
Analysis and robot pipelined automation for SELDI-TOF mass spectrometry.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2004;4():3068-71.
2004: Ahmad H Namini; David A Berkowicz; Isaac S Kohane; Henry C Chueh
A submission model for use in the indexing, searching, and retrieval of distributed pathology case and tissue specimens.
Studies in health technology and informatics 2004;107(Pt 2):1264-7.
2004: Brigham H Mecham; Gregory T Klus; Jeffrey Strovel; Meena Augustus; David Byrne; Peter Bozso; Daniel Z Wetmore; Thomas J Mariani; Isaac S Kohane; Zoltan Szallasi
Sequence-matched probes produce increased cross-platform consistency and more reproducible biological results in microarray-based gene expression measurements.
Nucleic acids research 2004;32(9):e74.
2003: Marc Ruel; Cesario Bianchi; Tanveer A Khan; Shu Xu; John R Liddicoat; Pierre Voisine; Eugenio G Araujo; Helen Lyon; Isaac S Kohane; Towia Libermann; Frank W Sellke
Gene expression profile after cardiopulmonary bypass and cardioplegic arrest.
The Journal of thoracic and cardiovascular surgery 2003;126(5):1521-30.
2003: Paola Sebastiani; Ross Lazarus; Scott Weiss; Louis Kunkel; Isaac S Kohane; Marco F Ramoni
Minimal haplotype tagging.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9900-5.
2003: Judith N Haslett; Despina Sanoudou; Alvin T Kho; Mei Han; Richard R Bennett; Isaac S Kohane; Alan H Beggs; Louis Kunkel
Gene expression profiling of Duchenne muscular dystrophy skeletal muscle.
Neurogenetics 2003;4(4):163-71.
2003: Ashish Nimgaonkar; Despina Sanoudou; Atul Butte; Judith N Haslett; Louis Kunkel; Alan H Beggs; Isaac S Kohane
Reproducibility of gene expression across generations of Affymetrix microarrays.
BMC bioinformatics 2003;4():27.
2003: Despina Sanoudou; Judith N Haslett; Alvin T Kho; Shaoqiang Guo; Hanna T Gazda; Steven A Greenberg; Hart G W Lidov; Isaac S Kohane; Louis Kunkel; Alan H Beggs
Expression profiling reveals altered satellite cell numbers and glycolytic enzyme transcription in nemaline myopathy muscle.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4666-71.
2003: Kyungjoon Lee; Isaac S Kohane; Atul Butte
PGAGENE: integrating quantitative gene-specific results from the NHLBI programs for genomic applications.
Bioinformatics (Oxford, England) 2003;19(6):778-9.
2003: Stephen C Porter; Gary R Fleisher; Isaac S Kohane; Kenneth D Mandl
The value of parental report for diagnosis and management of dehydration in the emergency department.
Annals of emergency medicine 2003;41(2):196-205.
2003: Sunil K Saluja; Isaac S Kohane
Localization and characterization of mouse-human alignments within the human genome. Does evolutionary conservation suggest functional importance?
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2003;():994.
2002: Alexander Turchin; Isaac S Kohane
Gene homology resources on the World Wide Web.
Physiological genomics 2002;11(3):165-77.
2002: Alberto Riva; Isaac S Kohane
SNPper: retrieval and analysis of human SNPs.
Bioinformatics (Oxford, England) 2002;18(12):1681-5.
2002: Peter J Park; Atul Butte; Isaac S Kohane
Comparing expression profiles of genes with similar promoter regions.
Bioinformatics (Oxford, England) 2002;18(12):1576-84.
2002: Judith N Haslett; Despina Sanoudou; Alvin T Kho; Richard R Bennett; Steven A Greenberg; Isaac S Kohane; Alan H Beggs; Louis Kunkel
Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):15000-5.
2002: Steven A Greenberg; Despina Sanoudou; Judith N Haslett; Isaac S Kohane; Louis Kunkel; Alan H Beggs; Anthony A Amato
Molecular profiles of inflammatory myopathies.
Neurology 2002;59(8):1170-82.
2002: Marco F Ramoni; Paola Sebastiani; Isaac S Kohane
Cluster analysis of gene expression dynamics.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9121-6.
2002: Qing Zhao; Alvin T Kho; Anna Marie Kenney; Dong-in Yuk Di; Isaac S Kohane; David H Rowitch
Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5704-9.
2002: Winston Kuo; Tor-Kristian Jenssen; Atul Butte; Lucila Ohno-Machado; Isaac S Kohane
Analysis of matched mRNA measurements from two different microarray technologies.
Bioinformatics (Oxford, England) 2002;18(3):405-12.
2002: Isaac S Kohane
The contributions of biomedical informatics to the fight against bioterrorism.
Journal of the American Medical Informatics Association : JAMIA 2002;9(2):116-9.
2002: Ju Han Kim; Isaac S Kohane; Lucila Ohno-Machado
Visualization and evaluation of clusters for exploratory analysis of gene expression data.
Journal of biomedical informatics 2002;35(1):25-36.
2002: Kenneth D Mandl; Shlomit Feit; Cecilia Larson; Isaac S Kohane
Newborn screening program practices in the United States: notification, research, and consent.
Pediatrics 2002;109(2):269-73.
2002: Asher D Schachter; Isaac S Kohane
An unsupervised self-optimizing gene clustering algorithm.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2002;():682-6.
2002: Alberto Riva; Isaac S Kohane
Accessing genomic data through XML-based remote procedure calls.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2002;():662-6.
2002: Zhaohui Cai; Isaac S Kohane; Gary R Fleisher; David S Greenes
Computerized reminders to physicians in the emergency department: a web-based system to report late-arriving abnormal laboratory results.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2002;():91-5.
2002: Peter J Park; Lu Tian; Isaac S Kohane
Linking gene expression data with patient survival times using partial least squares.
Bioinformatics (Oxford, England) 2002;18 Suppl 1():S120-7.
2001: Atul Butte; L Bao; B Y Reis; T W Watkins; Isaac S Kohane
Comparing the similarity of time-series gene expression using signal processing metrics.
Journal of biomedical informatics 2001;34(6):396-405.
2001: A Riva; Kenneth D Mandl; D H Oh; Daniel J Nigrin; Atul Butte; Peter Szolovits; Isaac S Kohane
The personal internetworked notary and guardian.
International journal of medical informatics 2001;62(1):27-40.
2001: Kenneth D Mandl; Peter Szolovits; Isaac S Kohane
Public standards and patients' control: how to keep electronic medical records accessible but private.
BMJ (Clinical research ed.) 2001;322(7281):283-7.
2001: Alberto Riva; Isaac S Kohane
A web-based tool to retrieve human genome polymorphisms from public databases.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2001;():558-62.
2001: Stephen C Porter; Isaac S Kohane
Optimal data entry by patients: effects of interface structure and design.
Studies in health technology and informatics 2001;84(Pt 1):141-5.
2000: Atul Butte; Pablo Tamayo; DK Slonim; Todd R Golub; Isaac S Kohane
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12182-6.
2000: David S Greenes; Gary R Fleisher; Isaac S Kohane
Potential impact of a computerized system to report late-arriving laboratory results in the emergency department.
Pediatric emergency care 2000;16(5):313-5.
2000: Joseph Gonzalez-Heydrich; David Ray DeMaso; C Irwin; Ronald J Steingard; Isaac S Kohane; William R Beardslee
Implementation of an electronic medical record system in a pediatric psychopharmacology program.
International journal of medical informatics 2000;57(2-3):109-16.
2000: Kenneth D Mandl; S Feit; Barbara M Garcia Peña; Isaac S Kohane
Growth and determinants of access in patient e-mail and Internet use.
Archives of pediatrics & adolescent medicine 2000;154(5):508-11.
2000: Stephen C Porter; M T Silvia; Gary R Fleisher; Isaac S Kohane; Charles J Homer; Kenneth D Mandl
Parents as direct contributors to the medical record: validation of their electronic input.
Annals of emergency medicine 2000;35(4):346-52.
2000: Daniel J Nigrin; Isaac S Kohane
Temporal expressiveness in querying a time-stamp--based clinical database.
Journal of the American Medical Informatics Association : JAMIA 2000;7(2):152-63.
2000: Daniel J Nigrin; Isaac S Kohane
Glucoweb: a case study of secure, remote biomonitoring and communication.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2000;():610-4.
2000: Isaac S Kohane; R B Altman
The new peer review.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2000;():433-7.
2000: Atul Butte; David A Weinstein; Isaac S Kohane
Enrolling patients into clinical trials faster using RealTime Recuiting.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 2000;():111-5.
1999: C Cao; N McIntosh; Isaac S Kohane; K Wang
Artifact detection in the PO2 and PCO2 time series monitoring data from preterm infants.
Journal of clinical monitoring and computing 1999;15(6):369-78.
1999: Joseph Gonzalez-Heydrich; Ronald J Steingard; F Putnam; William R Beardslee; Isaac S Kohane
Using 'off the shelf', computer programs to mine additional insights from published data: diurnal variation in potency of ACTH stimulation of cortisol secretion revealed.
Computer methods and programs in biomedicine 1999;58(3):227-38.
1999: Daniel J Nigrin; Isaac S Kohane
Scaling a data retrieval and mining application to the enterprise-wide level.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1999;():901-5.
1999: K D Mandl; Isaac S Kohane
Healthconnect: clinical grade patient-physician communication.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1999;():849-53.
1999: Atul Butte; Isaac S Kohane
Unsupervised knowledge discovery in medical databases using relevance networks.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1999;():711-5.
1999: C Cao; Isaac S Kohane; N McIntosh
Artifact detection in cardiovascular time series monitoring data from preterm infants.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1999;():207-11.
1999: Y Sun; FJ van Wingerde; Isaac S Kohane; OH Harary; Kenneth D Mandl; Susanne Salem-Schatz; Charles J Homer
The challenges of automating a real-time clinical practice guideline.
Clinical performance and quality health care 1999;7(1):28-35.
1998: K D Mandl; Isaac S Kohane; A M Brandt
Electronic patient-physician communication: problems and promise.
Annals of internal medicine 1998;129(6):495-500.
1998: Daniel J Nigrin; Isaac S Kohane
Data mining by clinicians.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1998;():957-61.
1998: FJ van Wingerde; Y Sun; OH Harary; Kenneth D Mandl; Susanne Salem-Schatz; Charles J Homer; Isaac S Kohane
Linking multiple heterogeneous data sources to practice guidelines.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1998;():391-5.
1998: Kenneth D Mandl; S B Katz; Isaac S Kohane
Social equity and access to the World Wide Web and E-mail: implications for design and implementation of medical applications.
Proceedings / AMIA ... Annual Symposium. AMIA Symposium 1998;():215-9.
1997: David M Rind; Isaac S Kohane; Peter Szolovits; Charles Safran; Henry C Chueh; G Octo Barnett
Maintaining the confidentiality of medical records shared over the Internet and the World Wide Web.
Annals of internal medicine 1997;127(2):138-41.
1997: K Wang; FJ van Wingerde; K Bradshaw; Peter Szolovits; Isaac S Kohane
A Java-based multi-institutional medical information retrieval system.
Proceedings : a conference of the American Medical Informatics Association / ... AMIA Annual Fall Symposium. AMIA Fall Symposium 1997;():538-42.
1996: I J Haimowitz; Isaac S Kohane
Managing temporal worlds for medical trend diagnosis.
Artificial intelligence in medicine 1996;8(3):299-321.
1996: Isaac S Kohane
Exploring the functions of World Wide Web-based electronic medical record systems.
M.D. computing : computers in medical practice 1996;13(4):339-46.
1996: Isaac S Kohane; P Greenspun; James C Fackler; Christopher Cimino; Peter Szolovits
Building national electronic medical record systems via the World Wide Web.
Journal of the American Medical Informatics Association : JAMIA 1996;3(3):191-207.
1996: K Wang; Isaac S Kohane; K L Bradshaw; James C Fackler
A real time patient monitoring system on the World Wide Web.
Proceedings : a conference of the American Medical Informatics Association / ... AMIA Annual Fall Symposium. AMIA Fall Symposium 1996;():729-32.
1996: F J van Wingerde; J Schindler; P Kilbridge; Peter Szolovits; Charles Safran; David M Rind; S Murphy; G Octo Barnett; Isaac S Kohane
Using HL7 and the World Wide Web for unifying patient data from remote databases.
Proceedings : a conference of the American Medical Informatics Association / ... AMIA Annual Fall Symposium. AMIA Fall Symposium 1996;():643-7.
1996: Isaac S Kohane; F J van Wingerde; James C Fackler; Christopher Cimino; P Kilbridge; S Murphy; Henry C Chueh; David M Rind; Charles Safran; O Barnett; Peter Szolovits
Sharing electronic medical records across multiple heterogeneous and competing institutions.
Proceedings : a conference of the American Medical Informatics Association / ... AMIA Annual Fall Symposium. AMIA Fall Symposium 1996;():608-12.
1995: I J Haimowitz; P P Le; Isaac S Kohane
Clinical monitoring using regression-based trend templates.
Artificial intelligence in medicine 1995;7(6):473-96.
1995: C M Gordon; D H Rowitch; M L Mitchell; Isaac S Kohane
Topical iodine and neonatal hypothyroidism.
Archives of pediatrics & adolescent medicine 1995;149(12):1336-9.
1995: D B Waisel; James C Fackler; Josef X Brunner; Isaac S Kohane
PEFIOS: an expert closed-loop oxygenation algorithm.
Medinfo. MEDINFO 1995;8 Pt 2():1132-6.
1995: P P Le; Isaac S Kohane; Jane C Weeks
Using a pen-based computer to collect health-related quality of life and utilities information.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1995;():839-43.
1995: A Hinds; P Greenspun; Isaac S Kohane
WHAM!: a forms constructor for medical record access via the World Wide Web.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1995;():116-20.
1994: Peter Szolovits; Isaac S Kohane
Against simple universal health-care identifiers.
Journal of the American Medical Informatics Association : JAMIA 1994;1(4):316-9.
1994: Rodica L Emanuel; B G Robinson; Ellen W Seely; Steven W Graves; Isaac S Kohane; D Saltzman; R Barbieri; Joseph A Majzoub
Corticotrophin releasing hormone levels in human plasma and amniotic fluid during gestation.
Clinical endocrinology 1994;40(2):257-62.
1994: James C Fackler; Isaac S Kohane
Monitor-driven data visualization: SmartDisplay.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1994;():939-43.
1994: Y Sun; Isaac S Kohane; A R Stark
Fuzzy logic assisted control of inspired oxygen in ventilated newborn infants.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1994;():757-61.
1994: Isaac S Kohane
Getting the data in: three year experience with a pediatric electronic medical record system.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1994;():457-61.
1994: Joseph Gonzalez-Heydrich; Ronald J Steingard; Isaac S Kohane
A computer simulation of the hypothalamic-pituitary-adrenal axis.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1994;():1010.
1993: Isaac S Kohane; I J Haimowitz
Hypothesis-driven data abstraction with trend templates.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1993;():444-8.
1991: I J Haimowitz; Isaac S Kohane
Influences on the performance of hospital clinical event monitoring.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1991;():614-8.